A Norwegian research team led by Professor Johanne Olweus has developed a new and groundbreaking method that offers the possibility of treating several aggressive forms of cancer. In an article published in Nature Immunology they propose that TCR-T cells targeting CTNNB1-S37F can serve as a basis for solid cancer immunotherapy.
The results have attracted international attention, and the research was recently featured in a major article in Norway's largest newspaper VG, entitled "Norwegian cancer study: –⁠ This is definitely a breakthrough".

Announcement from UiO Growth House:
Spend a day with great science, innovation and networking opportunities at this meeting place for academia, hospitals, the institute sector, the public sector, start-ups and industry.​ The conference is a part of Oslo Innovation Week 2025. Topics: antimicrobial resistance, cancer, neuroscience, materials science, social innovation, and women's health.
Time and place: Oct. 22, 2025 8:00 AM – 5:00 PM, Oslo Science Park, Gaustadalléen 21, Oslo

Programme and registration (from UiO Growth House)

The PREDI-LYNCH consortium officially launched its six-year Horizon Europe project with an in-person kickoff meeting in Heidelberg on September 18, 2025. The partners were welcomed by Project Coordinator Mev Dominguez-Valentin from the Institute for Cancer Research.
The event brought together more than 50 researchers, clinicians, and partners from across Europe. Funded under the EU Mission on Cancer, PREDI-LYNCH unites leading institutions and experts to improve screening, diagnostics, and risk prediction for individuals with a hereditary predisposition to cancer.

The National Research Archive (NVA) has replaced Cristin and is now open for both previous Cristin users and new contributors at OUS. Whether you're registering for the first time or updating your publications, NVA offers improved functionality for managing research outputs, including support for green open access and project code reporting.

Click More to learn how to get started, request editing access, and upload files for archiving.

The article "Targeting the roots of myeloid malignancies with T cell receptors" has been published online in the prestigious journal Nature Reviews Cancer.
Senior author is Johanna Olweus, head of the Experimental Immunotherapy Group at the Department of Cancer Immunology at the Insitute for Cancer Research.

The work is a collaboration with Sten Eirik Jacobsens group at Karolinska Institutet.

Link to the article (view only version)

Project leader Maja Radulovic and group leader Harald Stenmark at Department of Molecular Cell Biology, Institute for Cancer Research, have recently published a review in Nature Reviews Molecular Cell Biology entitled “Lysosomal membrane homeostasis and its importance in physiology and disease”. The motivation for this review is that lysosomes play a central role in disease progression, including neurodegenerative diseases and cancer, but also offer opportunities for novel therapies.