❭ Research by medical division ❭ Cancer Medicine ❭ Institute for Cancer Research ❭ Dept. of Cancer Genetics ❭ Translational studies on solid tumours [Helland] ❭ Clinical trials ❭ NIPU ❭

Malignant mesothelioma treated with immune checkpoint inhibitors 
with or without cancer vaccine (the NIPU-study)

– a phase II randomised clinical and translational trial

  • EudraCT number: 2019-002721-30 
  • Clinicaltrials.gov: NCT04300244
Background/study objectives
Study design
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Home Dept. of Cancer Genetics Translational studies on solid tumours [Helland]

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    • DART
    • NIPU
    • COM-IT-2
    • MATRIX-RARE
    • IMPRESS-Norway
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Recent publications

Rakaee M, Nassar AH, Tafavvoghi M, Jabar F, Bou Farhat E, Adib E, Andersen S, Busund LR, Pøhl M, Helland Å, Gusev A, Ricciuti B, Sholl LM, Donnem T, Kwiatkowski DJ (2026)
Ancestry-Associated Performance Variability of Open-Source AI Models for EGFR Prediction in Lung Cancer
JAMA Oncol (in press)
DOI 10.1001/jamaoncol.2025.6430, PubMed 41678173

Slørdahl KS, Puco K, Falk RS, Dyvik I, Brabrand S, Niehusmann P, Steinskog ESS, Blix ES, Flobak Å, Oppedal IA, Meltzer S, Torkildsen CF, Blakstad H, Lindemann K, Smeland S, Amundsen A, Taskén K, Helland Å, InPred Consortium (2026)
Clinical outcomes of genomically guided trametinib monotherapy across cancer types: results from the IMPRESS-Norway trial
Acta Oncol, 65, 90-96
DOI 10.2340/1651-226X.2026.45086, PubMed 41664938

Ystgaard MF, Myklebust TÅ, Smeby J, Larsen IK, Guren TK, Kure EH, Tveit KM, Glimelius B, Guren MG, Hamfjord J (2024)
Early-onset colorectal cancer incidence in Norway: a national registry-based study (1993-2022) analyzing subsite and morphology trends
ESMO Gastrointest Oncol, 7, 100065
DOI 10.1016/j.esmogo.2024.100065, PubMed 41646485

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