PUBLICATIONS OSLO FLOW CYTOMETRY CORE FACILITY 2018-2022

 

Publication list OUS FCCF 2018-2022

  1. Yin Y, Athanasiadis P, Karlsen L, Urban A, Murali I, Fernandes SM, Arribas AJ, Hilli AK, Taskén K, Bertoni F, Mato AR, Normant E, Brown JR, Tjønnfjord GE, Aittokallio T, Skånland SS. Functional testing of PI3K inhibitors stratifies responders to idelalisib and identifies treatment vulnerabilities in idelalisib-refractory/intolerant chronic lymphocytic leukemia. bioRxiv. 2022:2022.04.14.488428.
  2. Tunheim G, Ro GOI, Tran T, Kran AB, Andersen JT, Vaage EB, Kolderup A, Vaage JT, Lund-Johansen F, Hungnes O. Trends in seroprevalence of SARS-CoV-2 and infection fatality rate in the Norwegian population through the first year of the COVID-19 pandemic. Influenza Other Respir Viruses. 2022;16(2):204-12.
  3. Tunheim G, Ro GOI, Chopra A, Aase A, Kran AB, Vaage JT, Lund-Johansen F, Hungnes O. Prevalence of antibodies against SARS-CoV-2 in the Norwegian population, August 2021. Influenza Other Respir Viruses. 2022.
  4. Tran TT, Vaage EB, Mehta A, Chopra A, Kolderup A, Anthi A, König M, Nygaard G, Lind A, Müller F, Nissen-Meyer LS, Magnus P, Trogstad L, Mjaaland S, Søraas A, Midtvedt K, Åsberg A, Barratt-Due A, Medhus AW, Høivk ML, Lundin K, Karlsen RF, Dahle R, Danielsson K, Thomassen KS, Kro GB, Cox RJ, Zhou F, Langeland N, Aukrust P, Melum E, Åvitsland TL, Wiencke K, Holter JC, Munthe LA, Grødeland G, Andersen J-T, Vaage JT, Lund-Johansen F. Titers of antibodies the receptor-binding domain (RBD) of ancestral SARS-CoV-2 are predictive for levels of neutralizing antibodies to multiple variants. bioRxiv. 2022:2022.03.26.484261.
  5. Tesfaye DY, Bobic S, Lysen A, Huszthy PC, Gudjonsson A, Braathen R, Bogen B, Fossum E. Targeting Xcr1 on Dendritic Cells Rapidly Induce Th1-Associated Immune Responses That Contribute to Protection Against Influenza Infection. Front Immunol. 2022;13:752714.
  6. Tellez-Gabriel M, Tekpli X, Reine TM, Hegge B, Nielsen SR, Chen M, Moi L, Normann LS, Busund LR, Calin GA, Maelandsmo GM, Perander M, Theocharis AD, Kolset SO, Knutsen E. Serglycin Is Involved in TGF-beta Induced Epithelial-Mesenchymal Transition and Is Highly Expressed by Immune Cells in Breast Cancer Tissue. Front Oncol. 2022;12:868868.
  7. Søraas A, Grødeland G, Granerud BK, Ueland T, Lind A, Fevang B, Murphy S, Huse C, Nygaard AB, Steffensen AK, al-Baldawi H, Holberg-Petersen M, Andresen LL, Ågnes C, Ranheim T, Schanke Y, Istre M, Dahl JA, Chopra A, Dudman S, Kaarbø M, Andersen JT, Vaage EB, Tran TT, Vaage JT, Michelsen A, Müller F, Aukrust P, Halvorsen B, Børresdatter Dahl T, Holter JC, Lund-Johansen F. Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity. medRxiv; 2022.
  8. Syversen SW, Jyssum I, Tveter AT, Tran TT, Sexton J, Provan SA, Mjaaland S, Warren DJ, Kvien TK, Grodeland G, Nissen-Meyer LSH, Ricanek P, Chopra A, Andersson AM, Kro GB, Jahnsen J, Munthe LA, Haavardsholm EA, Vaage JT, Lund-Johansen F, Jorgensen KK, Goll GL. Immunogenicity and Safety of Standard and Third-Dose SARS-CoV-2 Vaccination in Patients Receiving Immunosuppressive Therapy. Arthritis Rheumatol. 2022;74(8):1321-32.
  9. Sudworth A, Segers FM, Yilmaz B, Guslund NC, Macpherson AJ, Dissen E, Qiao SW, Inngjerdingen M. Innate lymphoid cell characterization in the rat and their correlation to gut commensal microbes. Eur J Immunol. 2022;52(5):717-29.
  10. Solhaug MB, Schreurs O, Schenck K, Blix IJ, Baekkevold ES. Origin of langerin (CD207)-expressing antigen presenting cells in the normal oral mucosa and in oral lichen planus lesions. Eur J Oral Sci. 2022;130(1):e12835.
  11. Sohlberg E, Pfefferle A, Heggernes Ask E, Tschan-Plessl A, Jacobs B, Netskar H, Lorenz S, Kanaya M, Kosugi-Kanaya M, Meinke S, Mortberg A, Hoglund P, Sundin M, Carlsson G, Palmblad J, Malmberg KJ. Perturbed NK-cell homeostasis associated with disease severity in chronic neutropenia. Blood. 2022;139(5):704-16.
  12. Skogstad M, Aass HCD, Lunde LK, Skare O, Sirnes PA, Matre D. A Cease in Shift Work Reverses Arterial Stiffness but Increases Weight and Glycosylated Hemoglobin A 5-Month Follow-Up in Industry. J Cardiovasc Dev Dis. 2022;9(6).
  13. Skanland SS, Inngjerdingen M, Bendiksen H, York J, Spetalen S, Munthe LA, Tjonnfjord GE. Functional testing of relapsed chronic lymphocytic leukemia guides precision medicine and maps response and resistance mechanisms. An index case. Haematologica. 2022;107(8):1994-8.
  14. Shekhar S, Brar NK, Petersen FC. Suppressive effect of therapeutic antibiotic regimen on antipneumococcal Th1/Th17 responses in neonatal mice. Pediatr Res. 2022.
  15. Rye IH, Huse K, Josefsson SE, Kildal W, Danielsen HE, Schlichting E, Garred O, Riis ML, Osbreac, Lingjaerde OC, Myklebust JH, Russnes HG. Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression. Mol Oncol. 2022;16(1):88-103.
  16. Romaine A, Melleby AO, Alam J, Lobert VH, Lu N, Lockwood FE, Hasic A, Lunde IG, Sjaastad I, Stenmark H, Herum KM, Gullberg D, Christensen G. Integrin alpha11beta1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart. Am J Physiol Heart Circ Physiol. 2022;322(6):H1057-H71.
  17. Risnes LF, Chlubnova M, Magistrelli E, Kemppainen E, Hervonen K, Mansikka E, Lindfors K, Salmi T, Dahal-Koirala S, Sollid LM. Phenotypic Analysis of Disease-Relevant T Cells in Dermatitis Herpetiformis. J Invest Dermatol. 2022.
  18. Riise J, Meyer S, Blaas I, Chopra A, Tran TT, Delic-Sarac M, Hestdalen ML, Brodin E, Rustad EH, Dai KZ, Vaage JT, Nissen-Meyer LSH, Sund F, Wader KF, Bjornevik AT, Meyer PA, Nygaard GO, Konig M, Smeland S, Lund-Johansen F, Olweus J, Kolstad A. Rituximab-treated patients with lymphoma develop strong CD8 T-cell responses following COVID-19 vaccination. Br J Haematol. 2022;197(6):697-708.
  19. Quach HQ, Johnson C, Ekholt K, Islam R, Mollnes TE, Nilsson PH. Platelet-Depletion of Whole Blood Reveals That Platelets Potentiate the Release of IL-8 From Leukocytes Into Plasma in a Thrombin-Dependent Manner. Front Immunol. 2022;13:865386.
  20. Pataskar A, Champagne J, Nagel R, Kenski J, Laos M, Michaux J, Pak HS, Bleijerveld OB, Mordente K, Navarro JM, Blommaert N, Nielsen MM, Lovecchio D, Stone E, Georgiou G, de Gooijer MC, van Tellingen O, Altelaar M, Joosten RP, Perrakis A, Olweus J, Bassani-Sternberg M, Peeper DS, Agami R. Tryptophan depletion results in tryptophan-to-phenylalanine substitutants. Nature. 2022;603(7902):721-7.
  21. Palacios D, Momayyezi P, Huhn O, Ask EH, Dunst J, Malmberg KJ, Hammer Q. An optimized platform for efficient siRNA delivery into human NK cells. Eur J Immunol. 2022;52(7):1190-3.
  22. Nyakas M, Fleten KG, Haugen MH, Engedal N, Sveen C, Farstad IN, Florenes VA, Prasmickaite L, Maelandsmo GM, Seip K. AXL inhibition improves BRAF-targeted treatment in melanoma. Sci Rep. 2022;12(1):5076.
  23. Nilsen A, Hillestad T, Skingen VE, Aarnes EK, Fjeldbo CS, Hompland T, Evensen TS, Stokke T, Kristensen GB, Grallert B, Lyng H. miR-200a/b/-429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer. Mol Oncol. 2022;16(6):1402-19.
  24. Midtvedt K, Vaage JT, Heldal K, Munthe LA, Lund-Johansen F, Asberg A. Fourth dose of the SARS-CoV-2 vaccine in kidney transplant recipients with previously impaired humoral antibody response. Am J Transplant. 2022.
  25. Meyer-Myklestad MH, Medhus AW, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Stiksrud B, Troseid M, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Reikvam DH. Human Immunodeficiency Virus-Infected Immunological Nonresponders Have Colon-Restricted Gut Mucosal Immune Dysfunction. J Infect Dis. 2022;225(4):661-74.
  26. Melvold K, Giliberto M, Karlsen L, Ayuda-Duran P, Hanes R, Holien T, Enserink J, Brown JR, Tjonnfjord GE, Tasken K, Skanland SS. Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies. Mol Oncol. 2022;16(5):1153-70.
  27. Medeiros PMC, Schjalm C, Christiansen D, Sokolova M, Pischke SE, Wurzner R, Mollnes TE, Barratt-Due A. Vitamin C, Hydrocortisone, and the Combination Thereof Significantly Inhibited Two of Nine Inflammatory Markers Induced by Escherichia Coli But Not by Staphylococcus Aureus - When Incubated in Human Whole Blood. Shock. 2022;57(1):72-80.
  28. Lysen A, Gudjonsson A, Tesfaye DY, Bobic S, Bern M, Bogen B, Fossum E. Intranasal delivery of a cDC1 targeted influenza vaccine with poly(I:C) enhances T cell responses and protects against influenza infection. Scand J Immunol. 2022;95(3):e13128.
  29. Lindstad CB, du Pre MF, Stamnaes J, Sollid LM. Injection of prototypic celiac anti-transglutaminase 2 antibodies in mice does not cause enteropathy. PLoS One. 2022;17(4):e0266543.
  30. Lindeman I, Polak J, Qiao SW, Holmoy T, Hoglund RA, Vartdal F, Berg-Hansen P, Sollid LM, Lossius A. Stereotyped B-cell responses are linked to IgG constant region polymorphisms in multiple sclerosis. Eur J Immunol. 2022;52(4):550-65.
  31. Lee Y, Riskedal E, Kalleberg KT, Istre M, Lind A, Lund-Johansen F, Reiakvam O, Soraas AVL, Harris JR, Dahl JA, Hadley CL, Jugessur A. EWAS of post-COVID-19 patients shows methylation differences in the immune-response associated gene, IFI44L, three months after COVID-19 infection. Sci Rep. 2022;12(1):11478.
  32. Landsend ECS, Olafsson J, Lai X, Aass HCD, Utheim TP. Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels. J Ophthalmol. 2022;2022:5103231.
  33. Konig M, Torgauten HM, Tran TT, Holmoy T, Vaage JT, Lund-Johansen F, Nygaard GO. Immunogenicity and Safety of a Third SARS-CoV-2 Vaccine Dose in Patients With Multiple Sclerosis and Weak Immune Response After COVID-19 Vaccination. JAMA Neurol. 2022;79(3):307-9.
  34. Khodeer S, Klungland A, Dahl JA. ALKBH5 regulates somatic cell reprogramming in a phase-specific manner. J Cell Sci. 2022;135(11).
  35. Kasine T, Dyrhol-Riise AM, Barratt-Due A, Kildal AB, Olsen IC, Nezvalova-Henriksen K, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Berg A, Johannessen A, Heggelund L, Dahl TB, Halvorsen B, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR, Olsen RB, Tholin B, Ystrom CM, Skei NV, Hannula R, Dalgard O, Finbraten AK, Tonby K, Aballi S, Muller F, Mohn KG, Troseid M, Aukrust P, Ueland T, Group NO-SS. Neutrophil count predicts clinical outcome in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial. J Intern Med. 2022;291(2):241-3.
  36. Kared H, Wolf AS, Alirezaylavasani A, Ravussin A, Solum G, Tran TT, Lund-Johansen F, Vaage JT, Nissen-Meyer LS, Nygaard UC, Hungnes O, Robertson AH, Naess LM, Trogstad L, Magnus P, Munthe LA, Mjaaland S. Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults. Nat Commun. 2022;13(1):4165.
  37. Jyssum I, Kared H, Tran TT, Tveter AT, Provan SA, Sexton J, Jorgensen KK, Jahnsen J, Kro GB, Warren DJ, Vaage EB, Kvien TK, Nissen-Meyer LH, Anderson AM, Grodeland G, Haavardsholm EA, Vaage JT, Mjaaland S, Syversen SW, Lund-Johansen F, Munthe LA, Goll GL. Humoral and cellular immune responses to two and three doses of SARS-CoV-2 vaccines in rituximab-treated patients with rheumatoid arthritis: a prospective, cohort study. Lancet Rheumatol. 2022;4(3):e177-e87.
  38. Johnson C, Quach HQ, Lau C, Ekholt K, Espevik T, Woodruff TM, Pischke SE, Mollnes TE, Nilsson PH. Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood. J Immunol. 2022;208(12):2771-8.
  39. Jin Y, Lorvik KB, Jin Y, Beck C, Sike A, Persiconi I, Kvaloy E, Saatcioglu F, Dunn C, Kyte JA. Development of STEAP1 targeting chimeric antigen receptor for adoptive cell therapy against cancer. Mol Ther Oncolytics. 2022;26:189-206.
  40. Imbery JF, Heinzelbecker J, Jebsen JK, McGowan M, Myklebust C, Bottini N, Stanford SM, Skanland SS, Tveita A, Tjonnfjord GE, Munthe LA, Szodoray P, Nakken B. T-helper cell regulation of CD45 phosphatase activity by galectin-1 and CD43 governs chronic lymphocytic leukaemia proliferation. Br J Haematol. 2022;198(3):556-73.
  41. Hinke DM, Andersen TK, Gopalakrishnan RP, Skullerud LM, Werninghaus IC, Grodeland G, Fossum E, Braathen R, Bogen B. Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses. Cell Rep. 2022;39(9):110901.
  42. Giliberto M, Thimiri Govinda Raj DB, Cremaschi A, Skanland SS, Gade A, Tjonnfjord GE, Schjesvold F, Munthe LA, Tasken K. Ex vivo drug sensitivity screening in multiple myeloma identifies drug combinations that act synergistically. Mol Oncol. 2022;16(6):1241-58.
  43. Frick R, Hoydahl LS, Hodnebrug I, Vik ES, Dalhus B, Sollid LM, Gray JJ, Sandlie I, Loset GA. Affinity maturation of TCR-like antibodies using phage display guided by structural modeling. Protein Eng Des Sel. 2022;35.
  44. Foss S, Jonsson A, Bottermann M, Watkinson R, Lode HE, McAdam MB, Michaelsen TE, Sandlie I, James LC, Andersen JT. Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge. Sci Immunol. 2022;7(70):eabj1640.
  45. Fane A, Myhre MR, Inderberg EM, Walchli S. In vivo experimental mouse model to test CD19CAR T cells generated with different methods. Methods Cell Biol. 2022;167:149-61.
  46. Domanska D, Majid U, Karlsen VT, Merok MA, Beitnes AR, Yaqub S, Baekkevold ES, Jahnsen FL. Single-cell transcriptomic analysis of human colonic macrophages reveals niche-specific subsets. J Exp Med. 2022;219(3).
  47. Brunvoll SH, Nygaard AB, Ellingjord-Dale M, Holland P, Istre MS, Kalleberg KT, Søraas CL, Holven KB, Ulven SM, Hjartåker A, Haider T, Lund-Johansen F, Dahl JA, Meyer HE, Søraas A. Prevention of covid-19 and other acute respiratory infections with cod liver oil supplementation, a low dose vitamin D supplement: quadruple blinded, randomised placebo controlled trial. 2022;378:e071245.
  48. Bousquet PA, Meltzer S, Fuglestad AJ, Luders T, Esbensen Y, Juul HV, Johansen C, Lyckander LG, Bjornetro T, Inderberg EM, Kersten C, Redalen KR, Ree AH. The mitochondrial DNA constitution shaping T-cell immunity in patients with rectal cancer at high risk of metastatic progression. Clin Transl Oncol. 2022;24(6):1157-67.
  49. Bern M, Anthi A, Benjakul S, Kolderup A, Vaage E, Lode H, Vaysburd M, Nilsen J, Nyquist-Andersen M, Sakya S, Gjølberg T, Foss S, Moe M, Low B, Wiles M, Vaage J, Grodeland G, Sandlie I, James L, Lund-Johansen F, Andersen JT. A needle-free subunit vaccine platform inducing mucosal and systemic antibody immunity. Research Square; 2022.
  50. Bay LTE, Syljuasen RG, Landsverk HB. A novel, rapid and sensitive flow cytometry method reveals degradation of promoter proximal paused RNAPII in the presence and absence of UV. Nucleic Acids Res. 2022;50(15):e89.
  51. Bajor M, Graczyk-Jarzynka A, Marhelava K, Burdzinska A, Muchowicz A, Goral A, Zhylko A, Soroczynska K, Retecki K, Krawczyk M, Klopotowska M, Pilch Z, Paczek L, Malmberg KJ, Walchli S, Winiarska M, Zagozdzon R. PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells. J Immunother Cancer. 2022;10(1).
  52. Atlasy N, Bujko A, Baekkevold ES, Brazda P, Janssen-Megens E, Lundin KEA, Jahnsen J, Jahnsen FL, Stunnenberg HG. Single cell transcriptomic analysis of the immune cell compartment in the human small intestine and in Celiac disease. Nat Commun. 2022;13(1):4920.
  53. Anda EE, Braaten T, Borch KB, Nost TH, Chen SLF, Lukic M, Lund E, Forland F, Leon DA, Winje BA, Kran AB, Kalager M, Johansen FL, Sandanger TM. Seroprevalence of antibodies against SARS-CoV-2 in the adult population during the pre-vaccination period, Norway, winter 2020/21. Euro Surveill. 2022;27(13).
  54. Amundsen SF, Stamnaes J, du Pre MF, Sollid LM. Transglutaminase 2 affinity and enzyme-substrate intermediate stability as determining factors for T-cell responses to gluten peptides in celiac disease. Eur J Immunol. 2022;52(9):1474-81.
  55. Ali M, Giannakopoulou E, Li Y, Lehander M, Virding Culleton S, Yang W, Knetter C, Odabasi MC, Bollineni RC, Yang X, Foldvari Z, Boschen ML, Taraldsrud E, Stronen E, Toebes M, Hillen A, Mazzi S, de Ru AH, Janssen GMC, Kolstad A, Tjonnfjord GE, Lie BA, Griffioen M, Lehmann S, Osnes LT, Buechner J, Garcia KC, Schumacher TN, van Veelen PA, Leisegang M, Jacobsen SEW, Woll P, Olweus J. T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes. Nat Biotechnol. 2022;40(4):488-98.
  56. Aksnes M, Aass HCD, Tiiman A, Terenius L, Bogdanovic N, Vukojevic V, Knapskog AB. Serum Amyloidogenic Nanoplaques and Cytokines in Alzheimer's Disease: Pilot Study in a Small Naturalistic Memory Clinic Cohort. J Alzheimers Dis. 2022;86(3):1459-70.
  57. Aarsund M, Segers FM, Wu Y, Inngjerdingen M. Comparison of characteristics and tumor targeting properties of extracellular vesicles derived from primary NK cells or NK-cell lines stimulated with IL-15 or IL-12/15/18. Cancer Immunol Immunother. 2022;71(9):2227-38.
  58. Yao Y, Wyrozzemski L, Lundin KEA, Sandve GK, Qiao SW. Differential expression profile of gluten-specific T cells identified by single-cell RNA-seq. PLoS One. 2021;16(10):e0258029.
  59. Wyrozemski L, Sollid LM, Qiao SW. C-type lectin-like CD161 is not a co-signalling receptor in gluten-reactive CD4 + T cells. Scand J Immunol. 2021;93(6):e13016.
  60. Wong JJW, Selbo PK. Light-controlled elimination of PD-L1+ cells. J Photochem Photobiol B. 2021;225:112355.
  61. Vikan AK, Kostas M, Haugsten EM, Selbo PK, Wesche J. Efficacy and Selectivity of FGF2-Saporin Cytosolically Delivered by PCI in Cells Overexpressing FGFR1. Cells. 2021;10(6).
  62. Vestad B, Nyman TA, Hove-Skovsgaard M, Stensland M, Hoel H, Troseid AS, Aspelin T, Aass HCD, Puhka M, Hov JR, Nielsen SD, Ovstebo R, Troseid M. Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk. Sci Rep. 2021;11(1):21936.
  63. Valsalakumari R, Yadava SK, Szwed M, Pandya AD, Maelandsmo GM, Torgersen ML, Iversen TG, Skotland T, Sandvig K, Giri J. Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells. Int J Pharm. 2021;597:120217.
  64. Tschan-Plessl A, Kalberer CP, Wieboldt R, Stern M, Siegler U, Wodnar-Filipowicz A, Gerull S, Halter J, Heim D, Tichelli A, Tsakiris DA, Malmberg KJ, Passweg JR, Bottos A. Cellular immunotherapy with multiple infusions of in vitro-expanded haploidentical natural killer cells after autologous transplantation for patients with plasma cell myeloma. Cytotherapy. 2021;23(4):329-38.
  65. Tan KW, Nahse V, Campsteijn C, Brech A, Schink KO, Stenmark H. JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes. J Cell Sci. 2021;134(14).
  66. Tadele DS, Robertson J, Crispin R, Herrera MC, Chlubnova M, Piechaczyk L, Ayuda-Duran P, Singh SK, Gedde-Dahl T, Floisand Y, Skavland J, Wesche J, Gjertsen BT, Enserink JM. A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation. J Biol Chem. 2021;296:100179.
  67. Szodoray P, Andersen TK, Heinzelbecker J, Imbery JF, Huszthy PC, Stanford SM, Bogen B, Landsverk OB, Bottini N, Tveita A, Munthe LA, Nakken B. Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity. Cell Rep. 2021;36(6):109525.
  68. Szabo K, Jambor I, Szanto A, Horvath IF, Tarr T, Nakken B, Szodoray P, Papp G. The Imbalance of Circulating Follicular T Helper Cell Subsets in Primary Sjogren's Syndrome Associates With Serological Alterations and Abnormal B-Cell Distribution. Front Immunol. 2021;12:639975.
  69. Sikkeland LIB, Qiao SW, Ueland T, Myrdal O, Wyrozemski L, Aukrust P, Jahnsen FL, Sjaheim T, Kongerud J, Molberg O, Lund MB, Baekkevold ES. Lung CD4+ T-cells in patients with lung fibrosis produce pro-fibrotic interleukin-13 together with interferon-gamma. Eur Respir J. 2021;57(3).
  70. Shemesh O, Polak P, Lundin KEA, Sollid LM, Yaari G. Machine Learning Analysis of Naive B-Cell Receptor Repertoires Stratifies Celiac Disease Patients and Controls. Front Immunol. 2021;12:627813.
  71. Schultz NH, Sorvoll IH, Michelsen AE, Munthe LA, Lund-Johansen F, Ahlen MT, Wiedmann M, Aamodt AH, Skattor TH, Tjonnfjord GE, Holme PA. Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination. N Engl J Med. 2021;384(22):2124-30.
  72. Schink KO, Tan KW, Spangenberg H, Martorana D, Sneeggen M, Stevenin V, Enninga J, Campsteijn C, Raiborg C, Stenmark H. The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes. Nat Commun. 2021;12(1):6577.
  73. Rodland GE, Hauge S, Hasvold G, Bay LTE, Raabe TTH, Joel M, Syljuasen RG. Differential Effects of Combined ATR/WEE1 Inhibition in Cancer Cells. Cancers (Basel). 2021;13(15).
  74. Risnes LF, Eggesbo LM, Zuhlke S, Dahal-Koirala S, Neumann RS, Lundin KEA, Christophersen A, Sollid LM. Circulating CD103(+) gammadelta and CD8(+) T cells are clonally shared with tissue-resident intraepithelial lymphocytes in celiac disease. Mucosal Immunol. 2021;14(4):842-51.
  75. Qiao SW, Dahal-Koirala S, Eggesbo LM, Lundin KEA, Sollid LM. Frequency of Gluten-Reactive T Cells in Active Celiac Lesions Estimated by Direct Cell Cloning. Front Immunol. 2021;12:646163.
  76. Oksvold MP, Berglund UW, Gad H, Bai B, Stokke T, Rein ID, Pham T, Sanjiv K, Oy GF, Norum JH, Smeland EB, Myklebust JH, Helleday T, Vatsveen TK. Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma. Sci Rep. 2021;11(1):6317.
  77. Midtvedt K, Tran T, Parker K, Marti HP, Stenehjem AE, Goransson LG, Morkve Soldal K, Madsen C, Smedbraten J, Vaage EB, Lund-Johansen F, Asberg A. Low Immunization Rate in Kidney Transplant Recipients Also After Dose 2 of the BNT162b2 Vaccine: Continue to Keep Your Guard up! Transplantation. 2021;105(8):e80-e1.
  78. Meyer S, Blaas I, Bollineni RC, Delic-Sarac M, Tran TT, Knetter C, Dai K-Z, Støve Madssen T, Vaage JT, Gustavsen A, Yang W, Nissen-Meyer LSH, Douvlataniotis K, Laos M, Nielsen MM, Thiede B, Søraas A, Lund-Johansen F, Rustad EH, Olweus J. Public T-cell epitopes shared among SARS-CoV-2 variants are presented on prevalent HLA class I alleles. bioRxiv. 2021:2021.10.13.463911.
  79. Mensali N, Dillard P, Fayzullin A, Koksal H, Gaudernack G, Kvalheim G, Inderberg EM, Walchli S. "Built-in" PD-1 blocker to rescue NK-92 activity from PD-L1-mediated tumor escape mechanisms. FASEB J. 2021;35(9):e21750.
  80. Mandrup OA, Ong SC, Lykkemark S, Dinesen A, Rudnik-Jansen I, Dagnaes-Hansen NF, Andersen JT, Alvarez-Vallina L, Howard KA. Programmable half-life and anti-tumour effects of bispecific T-cell engager-albumin fusions with tuned FcRn affinity. Commun Biol. 2021;4(1):310.
  81. Lorvik KB, Meyer-Myklestad MH, Kushekar K, Handeland C, Medhus AW, Lund-Iversen M, Stiksrud B, Kvale D, Dyrhol-Riise AM, Tasken K, Reikvam DH. Enhanced Gut-Homing Dynamics and Pronounced Exhaustion of Mucosal and Blood CD4(+) T Cells in HIV-Infected Immunological Non-Responders. Front Immunol. 2021;12:744155.
  82. Lindstad CB, Qiao SW, Johannesen MK, Fugger L, Sollid LM, du Pre MF. Characterization of T-cell receptor transgenic mice recognizing immunodominant HLA-DQ2.5-restricted gluten epitopes. Eur J Immunol. 2021;51(4):1002-5.
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