Epigenetic regulation in breast cancer (emQTL)

Identification of epigenetically regulated pathways in cancer is possible using the expression methylation quantitative trait loci (emQTL) approach published in Fleischer, Tekpli et al. 2017. Using an improved version of this method, we have now identified epigenetic dysregulation associated with increased activity of the cell cycle, showing that epigenetic dysregulation in triple negative breast cancer may provide a growth advantage in these tumors. 



Jørgen Ankill, Thomas Fleischer 

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