Project overview

Chen Y, He L, Ianevski A, Ayuda-Durán P, Potdar S, Saarela J, Miettinen JJ, Kytölä S, Miettinen S, Manninen M, Heckman CA, Enserink JM, Wennerberg K, Aittokallio T (2023)
Robust scoring of selective drug responses for patient-tailored therapy selection
Nat Protoc (in press)
DOI 10.1038/s41596-023-00903-x, PubMed 37996540

Athanasiadis P, Ravikumar B, Elliott RJR, Dawson JC, Carragher NO, Clemons PA, Johanssen T, Ebner D, Aittokallio T (2023)
Chemogenomic library design strategies for precision oncology, applied to phenotypic profiling of glioblastoma patient cells
iScience, 26 (7), 107209
DOI 10.1016/j.isci.2023.107209, PubMed 37485377

Denisova OV, Merisaari J, Huhtaniemi R, Qiao X, Yetukuri L, Jumppanen M, Kaur A, Pääkkönen M, von Schantz-Fant С, Ohlmeyer M, Wennerberg K, Kauko O, Koch R, Aittokallio T, Taipale M, Westermarck J (2023)
PP2A-based triple-strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells
Mol Oncol, 17 (9), 1803-1820
DOI 10.1002/1878-0261.13488, PubMed 37458534