Project overview

Adnan Awad S, Dufva O, Ianevski A, Ghimire B, Koski J, Maliniemi P, Thomson D, Schreiber A, Heckman CA, Koskenvesa P, Korhonen M, Porkka K, Branford S, Aittokallio T, Kankainen M, Mustjoki S (2020)
RUNX1 mutations in blast-phase chronic myeloid leukemia associate with distinct phenotypes, transcriptional profiles, and drug responses
Leukemia (in press)
DOI 10.1038/s41375-020-01011-5, PubMed 32782381

Malani D, Yadav B, Kumar A, Potdar S, Kontro M, Kankainen M, Javarappa KK, Porkka K, Wolf M, Aittokallio T, Wennerberg K, Heckman CA, Murumägi A, Kallioniemi O (2020)
KIT pathway upregulation predicts dasatinib efficacy in acute myeloid leukemia
Leukemia
DOI 10.1038/s41375-020-0978-7, PubMed 32678289

Ianevski A, Giri AK, Gautam P, Kononov A, Potdar S, Saarela J, Wennerberg K, Aittokallio T (2019)
Prediction of drug combination effects with a minimal set of experiments
Nat Mach Intell, 1 (12), 568-577
DOI 10.1038/s42256-019-0122-4, PubMed 32368721