❭ Research by medical division ❭ Cancer Medicine ❭ Institute for Cancer Research ❭ Dept. of Cancer Genetics ❭ Computational Systems Medicine [Aittokallio] ❭ Projects ❭
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Project overview

Identification and characterization of drug resistant cell lineages with DNA barcoding
Multi-omics prediction of treatment outcomes for precision oncology applications
PANCAIM - pancreatic cancer AI for genomics and personalized medicine
Decision support systems for real-time patient monitoring and treatment optimization
 
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Home Dept. of Cancer Genetics Computational Systems Medicine [Aittokallio]

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Recent publications

Ravindran V, Wagoner J, Athanasiadis P, Den Hartigh AB, Sidorova JM, Ianevski A, Fink SL, Frigessi A, White J, Polyak SJ, Aittokallio T (2022)
Discovery of host-directed modulators of virus infection by probing the SARS-CoV-2-host protein-protein interaction network
Brief Bioinform, 23 (6)
DOI 10.1093/bib/bbac456, PubMed 36305426

Wang T, Pulkkinen OI, Aittokallio T (2022)
Target-specific compound selectivity for multi-target drug discovery and repurposing
Front Pharmacol, 13, 1003480
DOI 10.3389/fphar.2022.1003480, PubMed 36225560

Wagoner J, Herring S, Hsiang TY, Ianevski A, Biering SB, Xu S, Hoffmann M, Pöhlmann S, Gale M, Aittokallio T, Schiffer JT, White JM, Polyak SJ (2022)
Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2
Microbiol Spectr, 10 (5), e0333122
DOI 10.1128/spectrum.03331-22, PubMed 36190406

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