
Zhi Zhao
- Researcher; PhD
Interested in developing statistical methodologies for precision medicine, particularly personalized cancer therapies, to better understand the mechanisms of cancer progression and treatment response. Experienced with Bayesian hierarchical models and penalized likelihood approaches for identifying multi-omics biomarkers predictive of treatment response in cancer. Background in statistics, biostatistics, and statistical machine learning.
Publications 2026
A multi-center study on the consistency of drug sensitivity testing in patients with acute myeloid leukemia
NPJ Precis Oncol (in press)
DOI 10.1038/s41698-026-01480-4, PubMed 42135420
Publications 2025
Improved analysis of in vivo drug combination experiments with a comprehensive statistical framework and web-tool
Nat Commun, 16 (1), 10151
DOI 10.1038/s41467-025-65218-9, PubMed 41258298
Publications 2024
Integrative pan-cancer analysis reveals a common architecture of dysregulated transcriptional networks characterized by loss of enhancer methylation
PLoS Comput Biol, 20 (11), e1012565
DOI 10.1371/journal.pcbi.1012565, PubMed 39556603
Serum cytokines as a biomarker for immune checkpoint inhibitor toxicity in patients with pleural mesothelioma
Front Immunol, 15, 1480183
DOI 10.3389/fimmu.2024.1480183, PubMed 39687621
Bulk RNA sequencing for analysis of post COVID-19 condition in adolescents and young adults
J Transl Med, 22 (1), 312
DOI 10.1186/s12967-024-05117-7, PubMed 38532465
Tutorial on survival modeling with applications to omics data
Bioinformatics, 40 (3)
DOI 10.1093/bioinformatics/btae132, PubMed 38445722
Publications 2023
Bile acid metabolites in early pregnancy and risk of gestational diabetes mellitus: Results from a prospective cohort study
Diabetes Obes Metab, 25 (8), 2255-2267
DOI 10.1111/dom.15104, PubMed 37161712
Publications 2022
Tissue-specific identification of multi-omics features for pan-cancer drug response prediction
iScience, 25 (8), 104767
DOI 10.1016/j.isci.2022.104767, PubMed 35992090
EnrichIntersect: an R package for custom set enrichment analysis and interactive visualization of intersecting sets
Bioinform Adv, 2 (1), vbac073
DOI 10.1093/bioadv/vbac073, PubMed 36699400
Publications 2021
BayesSUR: An R Package for High-Dimensional Multivariate Bayesian Variable and Covariance Selection in Linear Regression
J. Stat. Softw., 100 (11), 1-32
DOI 10.18637/jss.v100.i11
Publications 2020
Automatic epileptic seizure classification in multichannel EEG time series with linear discriminant analysis
Technol Health Care, 28 (1), 23-33
DOI 10.3233/THC-181548, PubMed 31282443
Learning Cancer Drug Sensitivities in Large-Scale Screens from Multi-omics Data with Local Low-Rank Structure
Lecture Notes in Computer Science (LNCS), 12313, 67-79
DOI 10.1007/978-3-030-63061-4_7, PublikaID 380
Structured penalized regression for drug sensitivity prediction
J. R. Stat. Soc. Ser. C-Appl. Stat., 69 (3), 525-545
DOI 10.1111/rssc.12400
Publications 2017
Nomogram prediction for the survival of the patients with small cell lung cancer
J. Thorac. Dis., 9, 507
DOI 10.21037/jtd.2017.03.121, PublikaID 382
Time series analysis
In Handbook of Medical Statistics (Fang J, ed.), World Scientific Publishing, 269-299
DOI 10.1142/9789813148963_0009, PublikaID 381, ISBN 978-9813148956
Publications 2016
A novel three-dimensional smile analysis based on dynamic evaluation of facial curve contour
Sci. Rep., 6, 22103
DOI 10.1038/srep22103, PublikaID 383