Department of Molecular Oncology
|Ragnhild A. Lothe||Rolf I. Skotheim||Guro E. Lind|
A Norwegian Centre of Excellence funded by the Research Council of Norway.
Norwegian Cancer Genomics Consortium
K.G.Jebsen Colorectal Cancer Research Centre scientists participated with data from patients admitted to OUH in a multicenter study of >7000 stage II and III CRC recently reported in Annals of Oncology (Dienstmann et al).
Incorporation of MSI, BRAFV600E and KRAS mutation status to overall survival models with TNM staging improves the ability to precisely prognosticate in stage II and III CC patients, but only modestly increases prediction accuracy in multivariable models that include clinicopathological features, particularly in chemotherapy-treated patients.
The Norwegian Cancer Society calls attention to collaborative study on relevance of genetic heterogeneity
The Norwegian Cancer Society has recently presented a research project on their home page where researchers from Oslo and Bergen have performed genetic analyses on cancer cells that have spread from the gut to the liver. The results show that the degree of genetic heterogenenity between the tumors in the gut and in the liver respectively may reveal important prognostic information. The study led by Ragnhild A. Lothe from the Department of Moleceular Oncology at OUS and Per Eystein Lønning from Haukeland University Hospital.
Department of Molecular Oncology, Institute for Cancer Research
Oslo University Hospital HE - Norwegian Radium Hospital
Mail address: P. O. Box 4953 Nydalen, NO-0424 Oslo, Norway
Street address: Norwegian Radium Hospital, Montebello
Phone: +47 2278 1728, Switchboard: +47 2293 4000, Fax: +47 2278 1745
Aug 25, 2016
Aug 11, 2016
Aug 3, 2016
Dept of Molecular Oncology
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study
Lancet Gastroenterol Hepatol, 1 (3), 207-216
Bilateral ovarian carcinomas differ in the expression of metastasis-related genes
Oncol Lett, 13 (1), 184-190