Department of Molecular Oncology

 
 

Department head: Ragnhild A. Lothe, Professor
Department administrative consultants: Mona Hagen and Linda Uv Mjøen
Lab manager: Guro E. Lind

Research groups:

GeneticsGenome BiologyEpigenetics

Ragnhild A. LotheRolf I. SkotheimGuro E. Lind

Project group:

Cell signalling

 

Edward Leithe


Affiliations

Centre for Cancer Biomedicine  

Centre for Cancer Biomedicine

A Norwegian Centre of Excellence funded by the Research Council of Norway.

    
  

The K.G. Jebsen Colorectal Cancer Research Centre.

    

  

 

Norwegian Cancer Genomics Consortium

 


Latest News

 
 

Dr. Jarle Bruun's research profiled in the 2016 National report from the Health Regional Authorities

 

The report highlights clinically relevant research and projects ongoing in the KG Jebsen Colorectal cancer research centre was selected from the Health Region South East. Specifically, Dr Jarle Bruun's paper identifying the gene Regulator of chromosome condensation 2 (RCC2) as functionally important in colorectal cancer, and furthermore that changes of RCC2 at the DNA and protein level can identify clinically distinct subgroups of patients with inferior survival. This is the first paper that reports clinical relevance of RCC2 in cancer. Bruun has already contributed to two ongoing innovation projects from the Lothe group at the Department of Molecular Oncology, Institute for Cancer Research.

Forskning og innovasjon til pasientens beste - Nasjonal rapport fra spesialisthelsetjenesten 2016


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Three master's students graduated from the Department of Molecular Oncology

 

    

    

From left to right:

MSc Marthe Norreen Thorsen
The title of thesis:  "Functional evaluation of polo like kinase 1 (PLK1), a potential drug target, in malignant peripheral nerve sheath tumor cells"
Supervisors: Matthias Kolberg, Edward Leithe, and Ragnhild A. Lothe

MSc Mariella Evelyn Güere
The title of thesis:  "Identification of DNA methylation biomarkers for gastrointestinal cancer - Ubiquitin C-terminal hydrolase L1 (UCHL1)"
Supervisors: Hege Marie Vedeld and Guro E. Lind

MSc Kristina Totland Carm
The title of thesis:  "Investigation of DNA and RNA changes in multifocal prostate cancer - Identification of novel alterations and molecular subtyping of individual tumors"
Supervisors: Marte Løvf, Rolf Skotheim, and Ragnhild A. Lothe


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Contact information

Department of Molecular Oncology, Institute for Cancer Research
Oslo University Hospital HE - Norwegian Radium Hospital
Mail address: P. O. Box 4953 Nydalen, NO-0424 Oslo, Norway
Street address: Norwegian Radium Hospital, Montebello
Phone: +47 2278 1728, Switchboard: +47 2293 4000, Fax: +47 2278 1745
E-mail: ragnhild.a.lothe@rr-research.no