Immunogenetic studies of ME/CFS and autoimmune diseases with particular focus on HLA and KIR genes
Single cell profiling of immune cells in thymus to understand the establishment of self-tolerance and development of myasthenia gravis
Single immune cell phenotyping of blood and cerebrospinal fluid in ME/CFS and narcolepsy
Multiomic studies of immune cells with regards to disease activity and treatment response in rheumatoid arthritis and other autoimmune phenotypes
Exploring the phenotype of the immunological cells infiltrating the joint tissue and synovial fluid of the juvenile idiopathic arthritis patients by single cell technologies
Characterizing extracellular vesicles and their protein cargo in immunological diseases
Revealing biomarkers in blood for autoimmune diseases and treatment response
Hjorthaug HS, Heimli M, Flåm ST, Lie BA(2026) Multimodal single-cell profiling identifies nclTECs and links chromatin remodeling to TEC differentiation and self-antigen expression modes iScience, 29(8), 116916 DOI 10.1016/j.isci.2026.116916, PubMed 42569502
Rydland A, Yran ES, Nyman TA, Strand EB, Trøseid AS, Øvstebø R, Heinicke F, Lie BA, Viken MK(2026) Exploring differences in protein cargo of extracellular vesicles from ME/CFS patient plasma compared to healthy controls Biochem Biophys Rep, 47, 102679 DOI 10.1016/j.bbrep.2026.102679, PubMed 42375682
Ramadan DJ, Kichula KM, Tao S, Porfilio T, Lande A, Fluge Ø, Mella O, Strand EB, Saugstad OD, Norman PJ, Lie BA, Viken MK(2025) Killer cell immunoglobulin-like receptor (KIR) alleles suggested to be associated with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) Brain Behav Immun, 130, 106098 DOI 10.1016/j.bbi.2025.106098, PubMed 40897283
