Immunogenetic studies of ME/CFS and autoimmune diseases with particular focus on HLA and KIR genes
Single cell profiling of immune cells in thymus to understand the establishment of self-tolerance and development of myasthenia gravis
Single immune cell phenotyping of blood and cerebrospinal fluid in ME/CFS and narcolepsy
Multiomic studies of immune cells with regards to disease activity and treatment response in rheumatoid arthritis and other autoimmune phenotypes
Exploring the phenotype of the immunological cells infiltrating the joint tissue and synovial fluid of the juvenile idiopathic arthritis patients by single cell technologies
Characterizing extracellular vesicles and their protein cargo in immunological diseases
Revealing biomarkers in blood for autoimmune diseases and treatment response
Functional genomic studies of chronic low back pain patients with modic changes and response to antibiotic treatment
Heimli M, Tennebø Flåm S, Sagsveen Hjorthaug H, Bjørnstad PM, Chernigovskaya M, Le QK, Tekpli X, Greiff V, Lie BA(2023) Human thymic putative CD8αα precursors exhibit a biased TCR repertoire in single cell AIRR-seq Sci Rep, 13(1), 17714 DOI 10.1038/s41598-023-44693-4, PubMed 37853083
Vigeland MD, Flåm ST, Vigeland MD, Espeland A, Zucknick M, Wigemyr M, Bråten LCH, Gjefsen E, Zwart JA, Storheim K, Pedersen LM, Selmer K, Lie BA, Gervin K, The Aim Study Group(2023) Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes Antibiotics (Basel), 12(7) DOI 10.3390/antibiotics12071217, PubMed 37508313
Brun MK, Bjørlykke KH, Viken MK, Stenvik GE, Klaasen RA, Gehin JE, Warren DJ, Sexton J, Sandanger Ø, Kvien TK, Mørk C, Haavardsholm EA, Jahnsen J, Goll GL, Lie BA, Bolstad N, Jørgensen KK, Syversen SW(2023) HLA-DQ2 is associated with anti-drug antibody formation to infliximab in patients with immune-mediated inflammatory diseases J Intern Med, 293(5), 648-655 DOI 10.1111/joim.13616, PubMed 36843323