Publications by Benedicte A. Lie
197 publications found
Publications 2023
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HLA-DQ2 is associated with anti-drug antibody formation to infliximab in patients with immune-mediated inflammatory diseases
J Intern Med, 293 (5), 648-655
DOI 10.1111/joim.13616, PubMed 36843323 -
Multimodal human thymic profiling reveals trajectories and cellular milieu for T agonist selection
Front Immunol, 13, 1092028
DOI 10.3389/fimmu.2022.1092028, PubMed 36741401 -
Human thymic putative CD8αα precursors exhibit a biased TCR repertoire in single cell AIRR-seq
Sci Rep, 13 (1), 17714
DOI 10.1038/s41598-023-44693-4, PubMed 37853083 -
Small extracellular vesicles have distinct CD81 and CD9 tetraspanin expression profiles in plasma from rheumatoid arthritis patients
Clin Exp Med, 23 (6), 2867-2875
DOI 10.1007/s10238-023-01024-1, PubMed 36826611 -
Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes
Antibiotics (Basel), 12 (7)
DOI 10.3390/antibiotics12071217, PubMed 37508313 -
Increased muscle activity during sleep and more RBD symptoms in H1N1-(Pandemrix)-vaccinated narcolepsy type 1 patients compared with their non-narcoleptic siblings
Sleep, 46 (3)
DOI 10.1093/sleep/zsac316, PubMed 36562330
Publications 2022
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Genetic association study in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) identifies several potential risk loci
Brain Behav Immun, 102, 362-369
DOI 10.1016/j.bbi.2022.03.010, PubMed 35318112 -
Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1
PLoS Comput Biol, 18 (2), e1009059
DOI 10.1371/journal.pcbi.1009059, PubMed 35192601 -
The influence of HLA genotype on the development of metal hypersensitivity following joint replacement
Commun Med (Lond), 2, 73
DOI 10.1038/s43856-022-00137-0, PubMed 35761834 -
Erratum: Author Correction: The influence of HLA genotype on the development of metal hypersensitivity following joint replacement
Commun Med (Lond), 2, 91
DOI 10.1038/s43856-022-00158-9, PubMed 35856082 -
Identification of Novel Loci Shared by Juvenile Idiopathic Arthritis Subtypes Through Integrative Genetic Analysis
Arthritis Rheumatol, 74 (8), 1420-1429
DOI 10.1002/art.42129, PubMed 35347896 -
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Ann Rheum Dis, 81 (8), 1085-1095
DOI 10.1136/annrheumdis-2021-221754, PubMed 35470158 -
No replication of previously reported association with genetic variants in the T cell receptor alpha (TRA) locus for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
Transl Psychiatry, 12 (1), 277
DOI 10.1038/s41398-022-02046-1, PubMed 35821115 -
Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement
Sci Rep, 12 (1), 215
DOI 10.1038/s41598-021-04189-5, PubMed 34997115
Publications 2021
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T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
Nat Biotechnol, 40 (4), 488-498
DOI 10.1038/s41587-021-01089-x, PubMed 34873326 -
Next-Generation Sequencing Identifies Extended HLA Class I and II Haplotypes Associated With Early-Onset and Late-Onset Myasthenia Gravis in Italian, Norwegian, and Swedish Populations
Front Immunol, 12, 667336
DOI 10.3389/fimmu.2021.667336, PubMed 34163474 -
Polymorphisms in the TP53-MDM2-MDM4-axis in patients with rheumatoid arthritis
Gene, 793, 145747
DOI 10.1016/j.gene.2021.145747, PubMed 34077778 -
Methotrexate Treatment of Newly Diagnosed RA Patients Is Associated With DNA Methylation Differences at Genes Relevant for Disease Pathogenesis and Pharmacological Action
Front Immunol, 12, 713611
DOI 10.3389/fimmu.2021.713611, PubMed 34867944 -
Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests involvement of both HLA class I and class II loci
Brain Behav Immun, 98, 101-109
DOI 10.1016/j.bbi.2021.08.219, PubMed 34403736 -
MicroRNA Expression Differences in Blood-Derived CD19+ B Cells of Methotrexate Treated Rheumatoid Arthritis Patients
Front Immunol, 12, 663736
DOI 10.3389/fimmu.2021.663736, PubMed 33897713 -
The influence of HLA genotype on the severity of COVID-19 infection
HLA, 98 (1), 14-22
DOI 10.1111/tan.14284, PubMed 33896121 -
OBITUARY Erik Thorsby (1938-2021)
HLA, 98 (1), 3-4
DOI 10.1111/tan.14290 -
HLA-B*27 typing using a triplex real time PCR in routine laboratory
HLA, 98 (4), 366-369
DOI 10.1111/tan.14386, PubMed 34342381 -
Narcolepsy type 1 patients have lower levels of effector memory CD4+ T cells compared to their siblings when controlling for H1N1-(Pandemrix™)-vaccination and HLA DQB1∗06:02 status
Sleep Med, 85, 271-279
DOI 10.1016/j.sleep.2021.07.024, PubMed 34388506 -
High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y11 protein levels in narcolepsy type 1
Sleep, 44 (8)
DOI 10.1093/sleep/zsab062, PubMed 33710305
Publications 2020
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The effect of infliximab in patients with chronic low back pain and Modic changes (the BackToBasic study): study protocol of a randomized, double blind, placebo-controlled, multicenter trial
BMC Musculoskelet Disord, 21 (1), 698
DOI 10.1186/s12891-020-03720-5, PubMed 33087100 -
Rheumatoid Arthritis Patients, Both Newly Diagnosed and Methotrexate Treated, Show More DNA Methylation Differences in CD4+ Memory Than in CD4+ Naïve T Cells
Front Immunol, 11, 194
DOI 10.3389/fimmu.2020.00194, PubMed 32117312 -
An extension to: Systematic assessment of commercially available low-input miRNA library preparation kits
RNA Biol, 17 (9), 1284-1292
DOI 10.1080/15476286.2020.1761081, PubMed 32436772 -
Transcriptome profiling of human thymic CD4+ and CD8+ T cells compared to primary peripheral T cells
BMC Genomics, 21 (1), 350
DOI 10.1186/s12864-020-6755-1, PubMed 32393182 -
HLA and sleep parameter associations in post-H1N1 narcolepsy type 1 patients and first-degree relatives
Sleep, 43 (3)
DOI 10.1093/sleep/zsz239, PubMed 31606740 -
Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Sci Rep, 10 (1), 5267
DOI 10.1038/s41598-020-62157-x, PubMed 32210306 -
Intravenous Cyclophosphamide in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. An Open-Label Phase II Study
Front Med (Lausanne), 7, 162
DOI 10.3389/fmed.2020.00162, PubMed 32411717 -
Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing
Ann Rheum Dis, 80 (1), 109-117
DOI 10.1136/annrheumdis-2020-218636, PubMed 33037003 -
Maternal Microchimerism in Cord Blood and Risk of Celiac Disease in Childhood
J Pediatr Gastroenterol Nutr, 71 (3), 321-327
DOI 10.1097/MPG.0000000000002811, PubMed 32833392
Publications 2019
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Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial
BMJ, 367, l5654
DOI 10.1136/bmj.l5654, PubMed 31619437 -
Transcriptomes of antigen presenting cells in human thymus
PLoS One, 14 (7), e0218858
DOI 10.1371/journal.pone.0218858, PubMed 31261375 -
Systematic assessment of commercially available low-input miRNA library preparation kits
RNA Biol, 17 (1), 75-86
DOI 10.1080/15476286.2019.1667741, PubMed 31559901 -
HLA-DRB3*01:01 exhibits a dose-dependent impact on HPA-1a antibody levels in HPA-1a-immunized women
Blood Adv, 3 (7), 945-951
DOI 10.1182/bloodadvances.2019032227, PubMed 30923048 -
Maternal microchimerism in cord blood and risk of childhood-onset type 1 diabetes
Pediatr Diabetes, 20 (6), 728-735
DOI 10.1111/pedi.12875, PubMed 31173445 -
Maternal and Newborn Vitamin D-Binding Protein, Vitamin D Levels, Vitamin D Receptor Genotype, and Childhood Type 1 Diabetes
Diabetes Care, 42 (4), 553-559
DOI 10.2337/dc18-2176, PubMed 30692241 -
Accurate Adapter Information Is Crucial for Reproducibility and Reusability in Small RNA Seq Studies
Noncoding RNA, 5 (4)
DOI 10.3390/ncrna5040049, PubMed 31661777
Publications 2018
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Lack of Association among Peptidyl Arginine Deiminase Type 4 Autoantibodies, PADI4 Polymorphisms, and Clinical Characteristics in Rheumatoid Arthritis
J Rheumatol, 45 (9), 1211-1219
DOI 10.3899/jrheum.170769, PubMed 29858238 -
HLA -A, -C, -B, -DRB1, -DQB1 and -DPB1 allele and haplotype frequencies in 4514 healthy Norwegians
Hum Immunol, 79 (7), 527-529
DOI 10.1016/j.humimm.2018.04.012, PubMed 29684411 -
Prenatal iron exposure and childhood type 1 diabetes
Sci Rep, 8 (1), 9067
DOI 10.1038/s41598-018-27391-4, PubMed 29899542
Publications 2017
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HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry
HLA, 90 (4), 228-233
DOI 10.1111/tan.13076, PubMed 28695657 -
Maternal and neonatal vitamin D status, genotype and childhood celiac disease
PLoS One, 12 (7), e0179080
DOI 10.1371/journal.pone.0179080, PubMed 28686601 -
Juvenile myasthenia gravis in Norway: HLA-DRB1*04:04 is positively associated with prepubertal onset
PLoS One, 12 (10), e0186383
DOI 10.1371/journal.pone.0186383, PubMed 29036181 -
Fetal and Maternal Genetic Variants Influencing Neonatal Vitamin D Status
J Clin Endocrinol Metab, 102 (11), 4072-4079
DOI 10.1210/jc.2017-00827, PubMed 28938476 -
HLA class II alleles in Norwegian patients with coexisting type 1 diabetes and celiac disease
HLA, 89 (5), 278-284
DOI 10.1111/tan.12986, PubMed 28247576 -
Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases
JAMA Neurol, 74 (7), 780-792
DOI 10.1001/jamaneurol.2017.0469, PubMed 28586827
Publications 2016
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A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis
Am J Hum Genet, 100 (1), 64-74
DOI 10.1016/j.ajhg.2016.11.013, PubMed 28041642 -
Identification of a Natural Killer Cell Receptor Allele That Prolongs Survival of Cytomegalovirus-Positive Glioblastoma Patients
Cancer Res, 76 (18), 5326-36
DOI 10.1158/0008-5472.CAN-16-1162, PubMed 27406829 -
Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility
BMC Med Genet, 17, 24
DOI 10.1186/s12881-016-0285-3, PubMed 27005825 -
Genetic risk variants for autoimmune diseases that influence gene expression in thymus
Hum Mol Genet, 25 (14), 3117-3124
DOI 10.1093/hmg/ddw152, PubMed 27199374 -
Autoimmune risk variants in ERAP2 are associated with gene-expression levels in thymus
Genes Immun, 17 (7), 406-411
DOI 10.1038/gene.2016.39, PubMed 27829666 -
Migraine and frequent tension-type headache are not associated with multiple sclerosis in a Norwegian case-control study
Mult Scler J Exp Transl Clin, 2, 2055217316682976
DOI 10.1177/2055217316682976, PubMed 28607748 -
Antineutrophil antibodies define clinical and genetic subgroups in primary sclerosing cholangitis
Liver Int, 37 (3), 458-465
DOI 10.1111/liv.13238, PubMed 27558072 -
Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors
Mult Scler, 22 (14), 1783-1793
DOI 10.1177/1352458516635873, PubMed 26920376
Publications 2015
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Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
PLoS One, 10 (4), e0123057
DOI 10.1371/journal.pone.0123057, PubMed 25853426 -
Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms
PLoS One, 10 (5), e0128048
DOI 10.1371/journal.pone.0128048, PubMed 25978331 -
The association of PTPN22 rs2476601 with juvenile idiopathic arthritis is specific to females
Genes Immun, 16 (7), 495-8
DOI 10.1038/gene.2015.32, PubMed 26291515 -
Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1
Nat Commun, 6, 7146
DOI 10.1038/ncomms8146, PubMed 25994336 -
The Influence of the Autoimmunity-Associated Ancestral HLA Haplotype AH8.1 on the Human Gut Microbiota: A Cross-Sectional Study
PLoS One, 10 (7), e0133804
DOI 10.1371/journal.pone.0133804, PubMed 26207384 -
Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases
Nat Med, 21 (9), 1018-27
DOI 10.1038/nm.3933, PubMed 26301688 -
Genetic sharing and heritability of paediatric age of onset autoimmune diseases
Nat Commun, 6, 8442
DOI 10.1038/ncomms9442, PubMed 26450413 -
Catechol-O-methyltransferase (COMT) gene polymorphisms are associated with baseline disability but not long-term treatment outcome in patients with chronic low back pain
Eur Spine J, 24 (11), 2425-31
DOI 10.1007/s00586-015-3866-5, PubMed 25772090 -
ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients
Ann Rheum Dis, 74 (8), 1627-9
DOI 10.1136/annrheumdis-2015-207416, PubMed 25917849 -
Genome-Wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A and Identification of ZBTB10 and Three Distinct HLA Associations
Mol Med, 21 (1), 769-781
DOI 10.2119/molmed.2015.00232, PubMed 26562150
Publications 2014
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Coeliac disease-associated polymorphisms influence thymic gene expression
Genes Immun, 15 (6), 355-60
DOI 10.1038/gene.2014.26, PubMed 24871462 -
Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci
Mol Psychiatry, 20 (2), 207-14
DOI 10.1038/mp.2013.195, PubMed 24468824 -
VAV1 and BAFF, via NFκB pathway, are genetic risk factors for myasthenia gravis
Ann Clin Transl Neurol, 1 (5), 329-39
DOI 10.1002/acn3.51, PubMed 25356403 -
A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides
Ann Rheum Dis, 74 (3), e15
DOI 10.1136/annrheumdis-2013-204591, PubMed 24532677 -
Epistasis amongst PTPN2 and genes of the vitamin D pathway contributes to risk of juvenile idiopathic arthritis
J Steroid Biochem Mol Biol, 145, 113-20
DOI 10.1016/j.jsbmb.2014.10.012, PubMed 25460303 -
The HLA profiles of mixed connective tissue disease differ distinctly from the profiles of clinically related connective tissue diseases
Rheumatology (Oxford), 54 (3), 528-35
DOI 10.1093/rheumatology/keu310, PubMed 25187641 -
No association between multiple sclerosis and periodontitis after adjusting for smoking habits
Eur J Neurol, 22 (3), 588-90
DOI 10.1111/ene.12520, PubMed 25041906 -
Environmental exposures and the risk of multiple sclerosis investigated in a Norwegian case-control study
BMC Neurol, 14, 196
DOI 10.1186/s12883-014-0196-x, PubMed 25274070 -
Oligoclonal band phenotypes in MS differ in their HLA class II association, while specific KIR ligands at HLA class I show association to MS in general
J Neuroimmunol, 274 (1-2), 174-9
DOI 10.1016/j.jneuroim.2014.06.024, PubMed 25037176 -
Genome-wide ancestry patterns in Rapanui suggest pre-European admixture with Native Americans
Curr Biol, 24 (21), 2518-25
DOI 10.1016/j.cub.2014.09.057, PubMed 25447991 -
Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different from large duct disease
Liver Int, 34 (10), 1488-95
DOI 10.1111/liv.12492, PubMed 24517468 -
Refinement of the MHC risk map in a scandinavian primary sclerosing cholangitis population
PLoS One, 9 (12), e114486
DOI 10.1371/journal.pone.0114486, PubMed 25521205 -
Increased coagulation activity and genetic polymorphisms in the F5, F10 and EPCR genes are associated with breast cancer: a case-control study
BMC Cancer, 14, 845
DOI 10.1186/1471-2407-14-845, PubMed 25407022
Publications 2013
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Effects of coffee consumption, smoking, and hormones on risk for primary sclerosing cholangitis
Clin Gastroenterol Hepatol, 12 (6), 1019-28
DOI 10.1016/j.cgh.2013.09.024, PubMed 24076415 -
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci
Nat Genet, 45 (7), 730-8
DOI 10.1038/ng.2667, PubMed 23749187 -
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
Nat Genet, 45 (11), 1353-60
DOI 10.1038/ng.2770, PubMed 24076602 -
Genetic risk scores and number of autoantibodies in patients with rheumatoid arthritis
Ann Rheum Dis, 74 (4), 762-8
DOI 10.1136/annrheumdis-2013-204173, PubMed 24336335 -
Associations between APOE genotypes and disease susceptibility, joint damage and lipid levels in patients with rheumatoid arthritis
PLoS One, 8 (4), e60970
DOI 10.1371/journal.pone.0060970, PubMed 23613766 -
Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles
PLoS One, 8 (3), e58352
DOI 10.1371/journal.pone.0058352, PubMed 23472185 -
HLA-C alleles confer risk for anti-citrullinated peptide antibody-positive rheumatoid arthritis independent of HLA-DRB1 alleles
Rheumatology (Oxford), 52 (11), 1973-82
DOI 10.1093/rheumatology/ket252, PubMed 23901134 -
Treatment outcome of chronic low back pain and radiographic lumbar disc degeneration are associated with inflammatory and matrix degrading gene variants: a prospective genetic association study
BMC Musculoskelet Disord, 14, 105
DOI 10.1186/1471-2474-14-105, PubMed 23522322 -
Identification of the PTPN22 functional variant R620W as susceptibility genetic factor for giant cell arteritis
Ann Rheum Dis, 72 (11), 1882-1886
DOI 10.1136/annrheumdis-2013-203641, PubMed 23946333 -
Association of CD247 polymorphisms with rheumatoid arthritis: a replication study and a meta-analysis
PLoS One, 8 (7), e68295
DOI 10.1371/journal.pone.0068295, PubMed 23861880 -
The autoimmune-predisposing variant of lymphoid tyrosine phosphatase favors T helper 1 responses
Hum Immunol, 74 (5), 574-85
DOI 10.1016/j.humimm.2012.12.017, PubMed 23333624
Publications 2012
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Novel genetic association of the VTCN1 region with rheumatoid arthritis
Ann Rheum Dis, 71 (4), 567-71
DOI 10.1136/annrheumdis-2011-200574, PubMed 22323440 -
CIITA gene variants are associated with rheumatoid arthritis in Scandinavian populations
Genes Immun, 13 (5), 431-6
DOI 10.1038/gene.2012.11, PubMed 22513452 -
An Egyptian family with H syndrome due to a novel mutation in SLC29A3 illustrating overlapping features with pigmented hypertrichotic dermatosis with insulin-dependent diabetes and Faisalabad histiocytosis
Pediatr Diabetes, 14 (6), 466-72
DOI 10.1111/j.1399-5448.2012.00925.x, PubMed 22989030 -
Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08
Ann Neurol, 72 (6), 927-35
DOI 10.1002/ana.23691, PubMed 23055271 -
Multiple sclerosis-associated single-nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in the thymus
Genes Immun, 14 (1), 62-6
DOI 10.1038/gene.2012.52, PubMed 23151489 -
Importance of human leukocyte antigen (HLA) class I and II alleles on the risk of multiple sclerosis
PLoS One, 7 (5), e36779
DOI 10.1371/journal.pone.0036779, PubMed 22586495 -
Late onset myasthenia gravis is associated with HLA DRB1*15:01 in the Norwegian population
PLoS One, 7 (5), e36603
DOI 10.1371/journal.pone.0036603, PubMed 22590574 -
Polymorphisms of the BDNF gene show neither association with multiple sclerosis susceptibility nor clinical course
J Neuroimmunol, 244 (1-2), 107-10
DOI 10.1016/j.jneuroim.2012.01.011, PubMed 22341604 -
Association analysis of the CCL3L1 copy number locus by paralogue ratio test in Norwegian rheumatoid arthritis patients and healthy controls
Genes Immun, 13 (7), 579-82
DOI 10.1038/gene.2012.30, PubMed 22785612 -
An Association Study of Interleukin 18 Receptor Genes (IL18R1 and IL18RAP) in Lumbar Disc Degeneration
Open Orthop J, 6, 164-71
DOI 10.2174/1874325001206010164, PubMed 22550553 -
Genetic contribution of catechol-O-methyltransferase variants in treatment outcome of low back pain: a prospective genetic association study
BMC Musculoskelet Disord, 13, 76
DOI 10.1186/1471-2474-13-76, PubMed 22612913 -
Interaction analysis between HLA-DRB1 shared epitope alleles and MHC class II transactivator CIITA gene with regard to risk of rheumatoid arthritis
PLoS One, 7 (3), e32861
DOI 10.1371/journal.pone.0032861, PubMed 22461888 -
HLA-DRB1, -DQA1 and -DQB1 alleles and haplotypes in first-generation Pakistani immigrants in Norway
Scand J Immunol, 75 (4), 426-30
DOI 10.1111/j.1365-3083.2011.02669.x, PubMed 22171671 -
LYP inhibits T-cell activation when dissociated from CSK
Nat Chem Biol, 8 (5), 437-46
DOI 10.1038/nchembio.916, PubMed 22426112
Publications 2011
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No extreme genetic risk for type 1 diabetes among DR3/4-DQ8 siblings sharing both extended HLA haplotypes with their diabetic proband
Tissue Antigens, 77 (4), 338-40
DOI 10.1111/j.1399-0039.2011.01636.x, PubMed 21388358 -
Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy
PLoS Genet, 7 (7), e1002178
DOI 10.1371/journal.pgen.1002178, PubMed 21779181 -
[New gene map for multiple sclerosis]
Tidsskr Nor Laegeforen, 131 (21), 2126-30
DOI 10.4045/tidsskr.10.0823, PubMed 22048209 -
Electrostatic modifications of the human leukocyte antigen-DR P9 peptide-binding pocket and susceptibility to primary sclerosing cholangitis
Hepatology, 53 (6), 1967-76
DOI 10.1002/hep.24299, PubMed 21413052 -
FCRL3 -169C/C genotype is associated with anti-citrullinated protein antibody-positive rheumatoid arthritis and with radiographic progression
J Rheumatol, 38 (11), 2329-35
DOI 10.3899/jrheum.110489, PubMed 21885492 -
Evidence for PTPN22 R620W polymorphism as the sole common risk variant for rheumatoid arthritis in the 1p13.2 region
J Rheumatol, 38 (11), 2290-6
DOI 10.3899/jrheum.110361, PubMed 21965649 -
Interferon regulatory factor 5 gene polymorphism confers risk to several rheumatic diseases and correlates with expression of alternative thymic transcripts
Rheumatology (Oxford), 51 (4), 619-26
DOI 10.1093/rheumatology/ker364, PubMed 22179739 -
The PTPN22 R263Q polymorphism is a risk factor for rheumatoid arthritis in Caucasian case-control samples
Arthritis Rheum, 63 (2), 365-72
DOI 10.1002/art.30145, PubMed 21279993 -
Multiple loci in the HLA complex are associated with Addison's disease
J Clin Endocrinol Metab, 96 (10), E1703-8
DOI 10.1210/jc.2011-0645, PubMed 21816777 -
Proteasome immunosubunits protect against the development of CD8 T cell-mediated autoimmune diseases
J Immunol, 187 (5), 2302-9
DOI 10.4049/jimmunol.1101003, PubMed 21804012
Publications 2010
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A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort
Ann Rheum Dis, 70 (4), 638-41
DOI 10.1136/ard.2010.141838, PubMed 21187296 -
Primary sclerosing cholangitis in genetically diverse populations listed for liver transplantation: unique clinical and human leukocyte antigen associations
Liver Transpl, 16 (11), 1324-30
DOI 10.1002/lt.22161, PubMed 21031548 -
Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis
PLoS One, 5 (8), e12403
DOI 10.1371/journal.pone.0012403, PubMed 20811628 -
Two HLA class I genes independently associated with multiple sclerosis
J Neuroimmunol, 226 (1-2), 172-6
DOI 10.1016/j.jneuroim.2010.07.006, PubMed 20678810 -
Association to the Glypican-5 gene in multiple sclerosis
J Neuroimmunol, 226 (1-2), 194-7
DOI 10.1016/j.jneuroim.2010.07.003, PubMed 20692050 -
Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymus
Genes Immun, 12 (3), 191-8
DOI 10.1038/gene.2010.59, PubMed 21179112 -
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus
Nat Genet, 42 (5), 426-9
DOI 10.1038/ng.565, PubMed 20383147 -
Long-term muscular outcome and predisposing and prognostic factors in juvenile dermatomyositis: A case-control study
Arthritis Care Res (Hoboken), 62 (8), 1103-11
DOI 10.1002/acr.20203, PubMed 20506141 -
Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: a meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in four European populations
Arthritis Rheum, 62 (5), 1236-45
DOI 10.1002/art.27366, PubMed 20131291
Publications 2009
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Four novel coeliac disease regions replicated in an association study of a Swedish-Norwegian family cohort
Genes Immun, 11 (1), 79-86
DOI 10.1038/gene.2009.67, PubMed 19693089 -
Three microsatellites from the T1DGC MHC data set show highly significant association with type 1 diabetes, independent of the HLA-DRB1, -DQA1 and -DQB1 genes
Diabetes Obes Metab, 11 Suppl 1 (Suppl 1), 17-24
DOI 10.1111/j.1463-1326.2008.00999.x, PubMed 19143811 -
Norwegian Sami differs significantly from other Norwegians according to their HLA profile
Tissue Antigens, 75 (3), 207-17
DOI 10.1111/j.1399-0039.2009.01425.x, PubMed 20047643 -
Genome-wide association analysis in primary sclerosing cholangitis
Gastroenterology, 138 (3), 1102-11
DOI 10.1053/j.gastro.2009.11.046, PubMed 19944697 -
Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis
Ann Neurol, 65 (6), 658-66
DOI 10.1002/ana.21695, PubMed 19630074 -
A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis
Eur J Hum Genet, 18 (4), 502-4
DOI 10.1038/ejhg.2009.195, PubMed 19888296 -
Association analysis of the interleukin 17A gene in Caucasian rheumatoid arthritis patients from Norway and New Zealand
Rheumatology (Oxford), 48 (4), 367-70
DOI 10.1093/rheumatology/ken512, PubMed 19208686 -
HLA-DRB1 and month of birth in multiple sclerosis
Neurology, 73 (24), 2107-11
DOI 10.1212/WNL.0b013e3181c679f3, PubMed 20018638 -
A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis
Ann Rheum Dis, 69 (8), 1471-4
DOI 10.1136/ard.2009.114934, PubMed 19734133 -
Prediction of radiographic progression in rheumatoid arthritis and the role of antibodies against mutated citrullinated vimentin: results from a 10-year prospective study
Ann Rheum Dis, 69 (2), 345-51
DOI 10.1136/ard.2009.113092, PubMed 19648126 -
Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex
Genes Immun, 10 (4), 323-33
DOI 10.1038/gene.2009.13, PubMed 19295542
Publications 2008
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Association study of IL2/IL21 and FcgRIIa: significant association with the IL2/IL21 region in Scandinavian coeliac disease families
Genes Immun, 9 (4), 364-7
DOI 10.1038/gene.2008.27, PubMed 18418394 -
Conditional analyses on the T1DGC MHC dataset: novel associations with type 1 diabetes around HLA-G and confirmation of HLA-B
Genes Immun, 10 (1), 56-67
DOI 10.1038/gene.2008.74, PubMed 18830248 -
Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families
Genes Immun, 10 (2), 141-50
DOI 10.1038/gene.2008.88, PubMed 18987644 -
The SH2D2A gene and susceptibility to multiple sclerosis
J Neuroimmunol, 197 (2), 152-8
DOI 10.1016/j.jneuroim.2008.04.037, PubMed 18554728 -
A coding polymorphism in NALP1 confers risk for autoimmune Addison's disease and type 1 diabetes
Genes Immun, 10 (2), 120-4
DOI 10.1038/gene.2008.85, PubMed 18946481 -
Cholangiocarcinoma in primary sclerosing cholangitis is associated with NKG2D polymorphisms
Hepatology, 47 (1), 90-6
DOI 10.1002/hep.21964, PubMed 18023027
Publications 2007
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Fine mapping study in Scandinavian families suggests association between coeliac disease and haplotypes in chromosome region 5q32
Tissue Antigens, 71 (1), 27-34
DOI 10.1111/j.1399-0039.2007.00955.x, PubMed 17971050 -
A comprehensive screen for SNP associations on chromosome region 5q31-33 in Swedish/Norwegian celiac disease families
Eur J Hum Genet, 15 (9), 980-7
DOI 10.1038/sj.ejhg.5201870, PubMed 17551518 -
The FCRL3 -169T>C polymorphism is associated with rheumatoid arthritis and shows suggestive evidence of involvement with juvenile idiopathic arthritis in a Scandinavian panel of autoimmune diseases
Ann Rheum Dis, 67 (9), 1287-91
DOI 10.1136/ard.2007.077826, PubMed 18065500 -
Low frequency of the disease-associated DRB1*15-DQB1*06 haplotype may contribute to the low prevalence of multiple sclerosis in Sami
Tissue Antigens, 69 (4), 299-304
DOI 10.1111/j.1399-0039.2007.00803.x, PubMed 17389012 -
Particular genetic variants of ligands for natural killer cell receptors may contribute to the HLA associated risk of primary sclerosing cholangitis
J Hepatol, 46 (5), 899-906
DOI 10.1016/j.jhep.2007.01.032, PubMed 17383044 -
Different HLA class II associations in ulcerative colitis patients with and without primary sclerosing cholangitis
Genes Immun, 8 (3), 275-8
DOI 10.1038/sj.gene.6364377, PubMed 17301827 -
Molecular genetic studies of natives on Easter Island: evidence of an early European and Amerindian contribution to the Polynesian gene pool
Tissue Antigens, 69 (1), 10-8
DOI 10.1111/j.1399-0039.2006.00717.x, PubMed 17212703 -
Association analysis in type 1 diabetes of the PRSS16 gene encoding a thymus-specific serine protease
Hum Immunol, 68 (7), 592-8
DOI 10.1016/j.humimm.2007.03.009, PubMed 17584581 -
Associations between the PTPN22 1858C->T polymorphism and radiographic joint destruction in patients with rheumatoid arthritis: results from a 10-year longitudinal study
Ann Rheum Dis, 66 (12), 1604-9
DOI 10.1136/ard.2006.067892, PubMed 17472988 -
Lack of association between the chemokine receptor 5 polymorphism CCR5delta32 in rheumatoid arthritis and juvenile idiopathic arthritis
BMC Med Genet, 8, 33
DOI 10.1186/1471-2350-8-33, PubMed 17565662 -
The impact of HLA-A and -DRB1 on age at onset, disease course and severity in Scandinavian multiple sclerosis patients
Eur J Neurol, 14 (8), 835-40
DOI 10.1111/j.1468-1331.2007.01825.x, PubMed 17662002 -
The PTPN22 promoter polymorphism -1123G>C association cannot be distinguished from the 1858C>T association in a Norwegian rheumatoid arthritis material
Tissue Antigens, 70 (3), 190-7
DOI 10.1111/j.1399-0039.2007.00871.x, PubMed 17661906 -
Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis
Hum Immunol, 68 (9), 748-55
DOI 10.1016/j.humimm.2007.05.009, PubMed 17869649 -
Primary sclerosing cholangitis is associated with extended HLA-DR3 and HLA-DR6 haplotypes
Tissue Antigens, 69 (2), 161-9
DOI 10.1111/j.1399-0039.2006.00738.x, PubMed 17257319
Publications 2006
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Association analysis of MYO9B gene polymorphisms with celiac disease in a Swedish/Norwegian cohort
Hum Immunol, 67 (4-5), 341-5
DOI 10.1016/j.humimm.2006.03.020, PubMed 16720215 -
Association analysis of MYO9B gene polymorphisms and inflammatory bowel disease in a Norwegian cohort
Tissue Antigens, 68 (3), 249-52
DOI 10.1111/j.1399-0039.2006.00665.x, PubMed 16948647 -
FOXP3 polymorphisms in type 1 diabetes and coeliac disease
J Autoimmun, 27 (2), 140-4
DOI 10.1016/j.jaut.2006.06.007, PubMed 16996248 -
Linkage disequilibrium and haplotype blocks in the MHC vary in an HLA haplotype specific manner assessed mainly by DRB1*03 and DRB1*04 haplotypes
Genes Immun, 7 (2), 130-40
DOI 10.1038/sj.gene.6364272, PubMed 16395395 -
Analysis of MAdCAM-1 and ICAM-1 polymorphisms in 365 Scandinavian patients with primary sclerosing cholangitis
J Hepatol, 45 (5), 704-10
DOI 10.1016/j.jhep.2006.03.012, PubMed 16750586 -
Genetic polymorphisms associated with inflammatory bowel disease do not confer risk for primary sclerosing cholangitis
Am J Gastroenterol, 102 (1), 115-21
DOI 10.1111/j.1572-0241.2006.00928.x, PubMed 17100974 -
Polymorphisms in the steroid and xenobiotic receptor gene influence survival in primary sclerosing cholangitis
Gastroenterology, 131 (3), 781-7
DOI 10.1053/j.gastro.2006.05.057, PubMed 16952547 -
The 32-base pair deletion of the chemokine receptor 5 gene (CCR5-Delta32) is not associated with primary sclerosing cholangitis in 363 Scandinavian patients
Tissue Antigens, 68 (1), 78-81
DOI 10.1111/j.1399-0039.2006.00604.x, PubMed 16774544
Publications 2005
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CTLA4 polymorphisms are associated with vitiligo, in patients with concomitant autoimmune diseases
Pigment Cell Res, 18 (1), 55-8
DOI 10.1111/j.1600-0749.2004.00196.x, PubMed 15649153 -
Several genes in the extended human MHC contribute to predisposition to autoimmune diseases
Curr Opin Immunol, 17 (5), 526-31
DOI 10.1016/j.coi.2005.07.001, PubMed 16054351 -
Lack of association with the CD28/CTLA4/ICOS gene region among Norwegian multiple sclerosis patients
J Neuroimmunol, 166 (1-2), 197-201
DOI 10.1016/j.jneuroim.2005.06.002, PubMed 16005527 -
Systemic lupus erythematosus and the extended major histocompatibility complex--evidence for several predisposing loci
Rheumatology (Oxford), 44 (11), 1368-73
DOI 10.1093/rheumatology/kei015, PubMed 16174649 -
Celiac disease genetics: current concepts and practical applications
Clin Gastroenterol Hepatol, 3 (9), 843-51
DOI 10.1016/s1542-3565(05)00532-x, PubMed 16234020 -
HLA associated genetic predisposition to autoimmune diseases: Genes involved and possible mechanisms
Transpl Immunol, 14 (3-4), 175-82
DOI 10.1016/j.trim.2005.03.021, PubMed 15982560 -
Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases
Genes Immun, 6 (3), 271-3
DOI 10.1038/sj.gene.6364178, PubMed 15759012
Publications 2004
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Genetic analysis of the CD28/CTLA4/ICOS (CELIAC3) region in coeliac disease
Tissue Antigens, 64 (5), 593-9
DOI 10.1111/j.1399-0039.2004.00312.x, PubMed 15496203 -
Polymorphisms in the cytotoxic T lymphocyte antigen-4 gene region confer susceptibility to Addison's disease
J Clin Endocrinol Metab, 89 (7), 3474-6
DOI 10.1210/jc.2003-031854, PubMed 15240634 -
Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis
Tissue Antigens, 63 (3), 237-47
DOI 10.1111/j.0001-2815.2004.00173.x, PubMed 14989713 -
Genotype effects and epistasis in type 1 diabetes and HLA-DQ trans dimer associations with disease
Genes Immun, 5 (5), 381-8
DOI 10.1038/sj.gene.6364106, PubMed 15164102 -
CTLA-4 polymorphisms in allergy and asthma and the TH1/ TH2 paradigm
J Allergy Clin Immunol, 114 (2), 280-7
DOI 10.1016/j.jaci.2004.03.050, PubMed 15316504
Publications 2003
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Discussion of the role of hemochromatosis susceptibility gene mutation in protecting against iron deficiency in celiac disease
Gastroenterology, 124 (5), 1562-3; author reply 1564
DOI 10.1016/s0016-5085(03)00354-8, PubMed 12744238 -
Physical separation of HLA-A alleles by denaturing high-performance liquid chromatography
Tissue Antigens, 61 (6), 443-50
DOI 10.1034/j.1399-0039.2003.00058.x, PubMed 12823768 -
No evidence of type 1 diabetes susceptibility genes in the region centromeric of the HLA complex
Hum Immunol, 64 (10), 951-9
DOI 10.1016/s0198-8859(03)00172-1, PubMed 14522092 -
HLA associations in type 1 diabetes: DPB1 alleles may act as markers of other HLA-complex susceptibility genes
Tissue Antigens, 61 (5), 344-51
DOI 10.1034/j.1399-0039.2003.00055.x, PubMed 12753653 -
Evidence of at least two type 1 diabetes susceptibility genes in the HLA complex distinct from HLA-DQB1, -DQA1 and -DRB1
Genes Immun, 4 (1), 46-53
DOI 10.1038/sj.gene.6363917, PubMed 12595901 -
Coeliac disease patients carry conserved HLA-DR3-DQ2 haplotypes revealed by association of TNF alleles
Immunogenetics, 55 (5), 339-43
DOI 10.1007/s00251-003-0586-5, PubMed 12845502 -
An additional susceptibility gene for juvenile idiopathic arthritis in the HLA class I region on several DR-DQ haplotypes
Tissue Antigens, 61 (1), 80-4
DOI 10.1034/j.1399-0039.2003.610107.x, PubMed 12622778 -
Haplotype structure, LD blocks, and uneven recombination within the LRP5 gene
Genome Res, 13 (5), 845-55
DOI 10.1101/gr.563703, PubMed 12727905
Publications 2002
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Polymorphisms in the gene encoding thymus-specific serine protease in the extended HLA complex: a potential candidate gene for autoimmune and HLA-associated diseases
Genes Immun, 3 (5), 306-12
DOI 10.1038/sj.gene.6363858, PubMed 12140752 -
HLA in coeliac disease families: a novel test of risk modification by the 'other' haplotype when at least one DQA1*05-DQB1*02 haplotype is carried
Tissue Antigens, 60 (2), 147-54
DOI 10.1034/j.1399-0039.2002.600205.x, PubMed 12392509 -
A gene in the telomeric HLA complex distinct from HLA-A is involved in predisposition to juvenile idiopathic arthritis
Arthritis Rheum, 46 (6), 1614-9
DOI 10.1002/art.10337, PubMed 12115193
Publications 2001
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The polymorphism in the 3' untranslated region of IL12B has a negligible effect on the susceptibility to develop type 1 diabetes in Norway
Immunogenetics, 53 (7), 603-5
DOI 10.1007/s002510100370, PubMed 11685474 -
HLA complex genes in type 1 diabetes and other autoimmune diseases. Which genes are involved?
Trends Genet, 17 (2), 93-100
DOI 10.1016/s0168-9525(00)02180-6, PubMed 11173119
Publications 2000
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Application and interpretation of transmission/disequilibrium tests: transmission of HLA-DQ haplotypes to unaffected siblings in 526 families with type 1 diabetes
Am J Hum Genet, 66 (2), 740-3
DOI 10.1086/302780, PubMed 10677335 -
DR- and DQ-associated protection from type 1A diabetes: comparison of DRB1*1401 and DQA1*0102-DQB1*0602*
J Clin Endocrinol Metab, 85 (10), 3793-7
DOI 10.1210/jcem.85.10.6920, PubMed 11061540
Publications 1999
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A gene telomeric of the HLA class I region is involved in predisposition to both type 1 diabetes and coeliac disease
Tissue Antigens, 54 (2), 162-8
DOI 10.1034/j.1399-0039.1999.540207.x, PubMed 10488743 -
The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene
Am J Hum Genet, 64 (3), 793-800
DOI 10.1086/302283, PubMed 10053014 -
HLA associations in type 1 diabetes among patients not carrying high-risk DR3-DQ2 or DR4-DQ8 haplotypes
Tissue Antigens, 54 (6), 543-51
DOI 10.1034/j.1399-0039.1999.540602.x, PubMed 10674967
Publications 1997
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HLA associations in insulin-dependent diabetes mellitus: no independent association to particular DP genes
Hum Immunol, 55 (2), 170-5
DOI 10.1016/s0198-8859(97)00095-5, PubMed 9361969
Publications 1996
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Detection of psoriasis-associated antigen pso p27 in sarcoidosis bronchoalveolar lavage fluid using monoclonal antibodies
Clin Immunol Immunopathol, 81 (1), 82-7
DOI 10.1006/clin.1996.0161, PubMed 8808646
Publications 1995
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The psoriasis-associated antigen, pso p27, is expressed by tryptase-positive cells in psoriatic lesions
Arch Dermatol Res, 287 (5), 503-5
DOI 10.1007/BF00373437, PubMed 7625863