Publications by Ludvig Magne Sollid

274 publications found

Publications 2019

  1. Christophersen A, Lund EG, Snir O, Solà E, Kanduri C, Dahal-Koirala S, Zühlke S, Molberg Ø, Utz PJ, Rohani-Pichavant M, Simard JF, Dekker CL, Lundin KEA, Sollid LM, Davis MM (2019)
    Distinct phenotype of CD4+ T cells driving celiac disease identified in multiple autoimmune conditions
    Nat Med (in press)
    DOI 10.1038/s41591-019-0403-9, PubMed 30911136
  2. Gidoni M, Snir O, Peres A, Polak P, Lindeman I, Mikocziova I, Sarna VK, Lundin KEA, Clouser C, Vigneault F, Collins AM, Sollid LM, Yaari G (2019)
    Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping
    Nat Commun, 10 (1), 628
    DOI 10.1038/s41467-019-08489-3, PubMed 30733445
  3. Hung SC, Hou T, Jiang W, Wang N, Qiao SW, Chow IT, Liu X, van der Burg SH, Koelle DM, Kwok WW, Sollid LM, Mellins ED (2019)
    Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense
    J Immunol, 202 (9), 2558-2569
    DOI 10.4049/jimmunol.1801454, PubMed 30926644

Publications 2018

  1. Dahal-Koirala S, Ciacchi L, Petersen J, Risnes LF, Neumann RS, Christophersen A, Lundin KEA, Reid HH, Qiao SW, Rossjohn J, Sollid LM (2018)
    Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes
    J Biol Chem, 294 (3), 941-952
    DOI 10.1074/jbc.RA118.005736, PubMed 30455354
  2. Gunnarsen KS, Høydahl LS, Neumann RS, Bjerregaard-Andersen K, Nilssen NR, Sollid LM, Sandlie I, Løset GÅ (2018)
    Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system
    PLoS One, 13 (4), e0195868
    DOI 10.1371/journal.pone.0195868, PubMed 29649333
  3. Høydahl LS, Richter L, Frick R, Snir O, Gunnarsen KS, Landsverk OJB, Iversen R, Jeliazkov JR, Gray JJ, Bergseng E, Foss S, Qiao SW, Lundin KEA, Jahnsen J, Jahnsen FL, Sandlie I, Sollid LM, Løset GÅ (2018)
    Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease
    Gastroenterology, 156 (5), 1428-1439.e10
    DOI 10.1053/j.gastro.2018.12.013, PubMed 30593798
  4. Lindeman I, Emerton G, Mamanova L, Snir O, Polanski K, Qiao SW, Sollid LM, Teichmann SA, Stubbington MJT (2018)
    BraCeR: B-cell-receptor reconstruction and clonality inference from single-cell RNA-seq
    Nat Methods, 15 (8), 563-565
    DOI 10.1038/s41592-018-0082-3, PubMed 30065371
  5. Risnes LF, Christophersen A, Dahal-Koirala S, Neumann RS, Sandve GK, Sarna VK, Lundin KE, Qiao SW, Sollid LM (2018)
    Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease
    J Clin Invest, 128 (6), 2642-2650
    DOI 10.1172/JCI98819, PubMed 29757191
  6. Shao W, Pedrioli PGA, Wolski W, Scurtescu C, Schmid E, Vizcaíno JA, Courcelles M, Schuster H, Kowalewski D, Marino F, Arlehamn CSL, Vaughan K, Peters B, Sette A, Ottenhoff THM, Meijgaarden KE, Nieuwenhuizen N, Kaufmann SHE, Schlapbach R, Castle JC, Nesvizhskii AI, Nielsen M, Deutsch EW, Campbell DS, Moritz RL et al. (2018)
    The SysteMHC Atlas project
    Nucleic Acids Res, 46 (D1), D1237-D1247
    DOI 10.1093/nar/gkx664, PubMed 28985418
  7. Tutturen AEV, Dørum S, Clancy T, Reims HM, Christophersen A, Lundin KEA, Sollid LM, de Souza GA, Stamnaes J (2018)
    Characterization of the Small Intestinal Lesion in Celiac Disease by Label-Free Quantitative Mass Spectrometry
    Am J Pathol, 188 (7), 1563-1579
    DOI 10.1016/j.ajpath.2018.03.017, PubMed 29684362

Publications 2017

  1. Goel G, King T, Daveson AJ, Andrews JM, Krishnarajah J, Krause R, Brown GJE, Fogel R, Barish CF, Epstein R, Kinney TP, Miner PB, Tye-Din JA, Girardin A, Taavela J, Popp A, Sidney J, Mäki M, Goldstein KE, Griffin PH, Wang S, Dzuris JL, Williams LJ, Sette A, Xavier RJ et al. (2017)
    Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies
    Lancet Gastroenterol Hepatol, 2 (7), 479-493
    DOI 10.1016/S2468-1253(17)30110-3, PubMed 28506538
  2. Gunnarsen KS, Høydahl LS, Risnes LF, Dahal-Koirala S, Neumann RS, Bergseng E, Frigstad T, Frick R, du Pré MF, Dalhus B, Lundin KE, Qiao SW, Sollid LM, Sandlie I, Løset GÅ (2017)
    A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions
    JCI Insight, 2 (17)
    DOI 10.1172/jci.insight.95193, PubMed 28878121
  3. Iversen R, Snir O, Stensland M, Kroll JE, Steinsbø Ø, Korponay-Szabó IR, Lundin KEA, de Souza GA, Sollid LM (2017)
    Strong Clonal Relatedness between Serum and Gut IgA despite Different Plasma Cell Origins
    Cell Rep, 20 (10), 2357-2367
    DOI 10.1016/j.celrep.2017.08.036, PubMed 28877470
  4. Jabri B, Sollid LM (2017)
    T Cells in Celiac Disease
    J Immunol, 198 (8), 3005-3014
    DOI 10.4049/jimmunol.1601693, PubMed 28373482
  5. Landsverk OJ, Snir O, Casado RB, Richter L, Mold JE, Réu P, Horneland R, Paulsen V, Yaqub S, Aandahl EM, Øyen OM, Thorarensen HS, Salehpour M, Possnert G, Frisén J, Sollid LM, Baekkevold ES, Jahnsen FL (2017)
    Antibody-secreting plasma cells persist for decades in human intestine
    J Exp Med, 214 (2), 309-317
    DOI 10.1084/jem.20161590, PubMed 28104812
  6. Nguyen TB, Jayaraman P, Bergseng E, Madhusudhan MS, Kim CY, Sollid LM (2017)
    Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides
    J Biol Chem, 292 (22), 9218-9228
    DOI 10.1074/jbc.M117.785139, PubMed 28364043
  7. Ráki M, Dahal-Koirala S, Yu H, Korponay-Szabó IR, Gyimesi J, Castillejo G, Jahnsen J, Qiao SW, Sollid LM (2017)
    Similar Responses of Intestinal T Cells From Untreated Children and Adults With Celiac Disease to Deamidated Gluten Epitopes
    Gastroenterology, 153 (3), 787-798.e4
    DOI 10.1053/j.gastro.2017.05.016, PubMed 28535873
  8. Roy B, Neumann RS, Snir O, Iversen R, Sandve GK, Lundin KEA, Sollid LM (2017)
    High-Throughput Single-Cell Analysis of B Cell Receptor Usage among Autoantigen-Specific Plasma Cells in Celiac Disease
    J Immunol, 199 (2), 782-791
    DOI 10.4049/jimmunol.1700169, PubMed 28600290
  9. Sarna VK, Lundin KEA, Mørkrid L, Qiao SW, Sollid LM, Christophersen A (2017)
    HLA-DQ-Gluten Tetramer Blood Test Accurately Identifies Patients With and Without Celiac Disease in Absence of Gluten Consumption
    Gastroenterology, 154 (4), 886-896.e6
    DOI 10.1053/j.gastro.2017.11.006, PubMed 29146521
  10. Sarna VK, Skodje GI, Reims HM, Risnes LF, Dahal-Koirala S, Sollid LM, Lundin KEA (2017)
    HLA-DQ:gluten tetramer test in blood gives better detection of coeliac patients than biopsy after 14-day gluten challenge
    Gut, 67 (9), 1606-1613
    DOI 10.1136/gutjnl-2017-314461, PubMed 28779027
  11. Snir O, Chen X, Gidoni M, du Pré MF, Zhao Y, Steinsbø Ø, Lundin KE, Yaari G, Sollid LM (2017)
    Stereotyped antibody responses target posttranslationally modified gluten in celiac disease
    JCI Insight, 2 (17)
    DOI 10.1172/jci.insight.93961, PubMed 28878138
  12. Sollid LM (2017)
    The roles of MHC class II genes and post-translational modification in celiac disease
    Immunogenetics, 69 (8-9), 605-616
    DOI 10.1007/s00251-017-0985-7, PubMed 28695286
  13. Sollid LM, Lycke N (2017)
    Per Brandtzaeg: patron of mucosal immunology
    Mucosal Immunol, 10 (1), 1-4
    DOI 10.1038/mi.2016.111, PubMed 28138161
  14. Viken MK, Flåm ST, Skrivarhaug T, Amundsen SS, Sollid LM, Drivvoll AK, Joner G, Dahl-Jørgensen K, Lie BA (2017)
    HLA class II alleles in Norwegian patients with coexisting type 1 diabetes and celiac disease
    HLA, 89 (5), 278-284
    DOI 10.1111/tan.12986, PubMed 28247576

Publications 2016

  1. Cardoso I, Østerlund EC, Stamnaes J, Iversen R, Andersen JT, Jørgensen TJ, Sollid LM (2016)
    Dissecting the interaction between transglutaminase 2 and fibronectin
    Amino Acids, 49 (3), 489-500
    DOI 10.1007/s00726-016-2296-y, PubMed 27394141
  2. Christophersen A, Risnes LF, Bergseng E, Lundin KE, Sollid LM, Qiao SW (2016)
    Healthy HLA-DQ2.5+ Subjects Lack Regulatory and Memory T Cells Specific for Immunodominant Gluten Epitopes of Celiac Disease
    J Immunol, 196 (6), 2819-26
    DOI 10.4049/jimmunol.1501152, PubMed 26895834
  3. Dahal-Koirala S, Risnes LF, Christophersen A, Sarna VK, Lundin KE, Sollid LM, Qiao SW (2016)
    TCR sequencing of single cells reactive to DQ2.5-glia-α2 and DQ2.5-glia-ω2 reveals clonal expansion and epitope-specific V-gene usage
    Mucosal Immunol, 9 (3), 587-96
    DOI 10.1038/mi.2015.147, PubMed 26838051
  4. Dørum S, Steinsbø Ø, Bergseng E, Arntzen MØ, de Souza GA, Sollid LM (2016)
    Gluten-specific antibodies of celiac disease gut plasma cells recognize long proteolytic fragments that typically harbor T-cell epitopes
    Sci Rep, 6, 25565
    DOI 10.1038/srep25565, PubMed 27146306
  5. Hnida K, Stamnaes J, du Pré MF, Mysling S, Jørgensen TJ, Sollid LM, Iversen R (2016)
    Epitope-dependent Functional Effects of Celiac Disease Autoantibodies on Transglutaminase 2
    J Biol Chem, 291 (49), 25542-25552
    DOI 10.1074/jbc.M116.738161, PubMed 27784785
  6. Høydahl LS, Nilssen NR, Gunnarsen KS, Pré MF, Iversen R, Roos N, Chen X, Michaelsen TE, Sollid LM, Sandlie I, Løset GÅ (2016)
    Multivalent pIX phage display selects for distinct and improved antibody properties
    Sci Rep, 6, 39066
    DOI 10.1038/srep39066, PubMed 27966617
  7. Spencer J, Sollid LM (2016)
    The human intestinal B-cell response
    Mucosal Immunol, 9 (5), 1113-24
    DOI 10.1038/mi.2016.59, PubMed 27461177
  8. Stamnaes J, Cardoso I, Iversen R, Sollid LM (2016)
    Transglutaminase 2 strongly binds to an extracellular matrix component other than fibronectin via its second C-terminal beta-barrel domain
    FEBS J, 283 (21), 3994-4010
    DOI 10.1111/febs.13907, PubMed 27685605

Publications 2015

  1. Cardoso I, Stamnaes J, Andersen JT, Melino G, Iversen R, Sollid LM (2015)
    Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies
    FEBS J, 282 (11), 2063-75
    DOI 10.1111/febs.13276, PubMed 25808416
  2. Chen X, Hnida K, Graewert MA, Andersen JT, Iversen R, Tuukkanen A, Svergun D, Sollid LM (2015)
    Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease
    J Biol Chem, 290 (35), 21365-75
    DOI 10.1074/jbc.M115.669895, PubMed 26160175
  3. Di Niro R, Snir O, Kaukinen K, Yaari G, Lundin KE, Gupta NT, Kleinstein SH, Cols M, Cerutti A, Mäki M, Shlomchik MJ, Sollid LM (2015)
    Responsive population dynamics and wide seeding into the duodenal lamina propria of transglutaminase-2-specific plasma cells in celiac disease
    Mucosal Immunol, 9 (1), 254-64
    DOI 10.1038/mi.2015.57, PubMed 26153762
  4. du Pré MF, Sollid LM (2015)
    T-cell and B-cell immunity in celiac disease
    Best Pract Res Clin Gastroenterol, 29 (3), 413-23
    DOI 10.1016/j.bpg.2015.04.001, PubMed 26060106
  5. Iversen R, Fleur du Pré M, Di Niro R, Sollid LM (2015)
    Igs as Substrates for Transglutaminase 2: Implications for Autoantibody Production in Celiac Disease
    J Immunol, 195 (11), 5159-68
    DOI 10.4049/jimmunol.1501363, PubMed 26503953
  6. Lundin KE, Qiao SW, Snir O, Sollid LM (2015)
    Coeliac disease - from genetic and immunological studies to clinical applications
    Scand J Gastroenterol, 50 (6), 708-17
    DOI 10.3109/00365521.2015.1030766, PubMed 25846940
  7. Riaz T, Sollid LM, Olsen I, de Souza GA (2015)
    Quantitative Proteomics of Gut-Derived Th1 and Th1/Th17 Clones Reveal the Presence of CD28+ NKG2D- Th1 Cytotoxic CD4+ T cells
    Mol Cell Proteomics, 15 (3), 1007-16
    DOI 10.1074/mcp.M115.050138, PubMed 26637539
  8. Snir O, Mesin L, Gidoni M, Lundin KE, Yaari G, Sollid LM (2015)
    Analysis of celiac disease autoreactive gut plasma cells and their corresponding memory compartment in peripheral blood using high-throughput sequencing
    J Immunol, 194 (12), 5703-12
    DOI 10.4049/jimmunol.1402611, PubMed 25972486
  9. Sollid LM, Iversen R, Steinsbø Ø, Qiao SW, Bergseng E, Dørum S, du Pré MF, Stamnaes J, Christophersen A, Cardoso I, Hnida K, Chen X, Snir O, Lundin KE (2015)
    Small bowel, celiac disease and adaptive immunity
    Dig Dis, 33 (2), 115-21
    DOI 10.1159/000369512, PubMed 25925911
  10. Stamnaes J, Iversen R, du Pré MF, Chen X, Sollid LM (2015)
    Enhanced B-Cell Receptor Recognition of the Autoantigen Transglutaminase 2 by Efficient Catalytic Self-Multimerization
    PLoS One, 10 (8), e0134922
    DOI 10.1371/journal.pone.0134922, PubMed 26244572
  11. Stamnaes J, Sollid LM (2015)
    Celiac disease: Autoimmunity in response to food antigen
    Semin Immunol, 27 (5), 343-52
    DOI 10.1016/j.smim.2015.11.001, PubMed 26603490
  12. Steinsbø Ø, Dørum S, Lundin KE, Sollid LM (2015)
    Serologic assay for diagnosis of celiac disease based on a patient-derived monoclonal antigliadin antibody
    Gastroenterology, 149 (6), 1530-1540.e3
    DOI 10.1053/j.gastro.2015.07.008, PubMed 26208894

Publications 2014

  1. Amundsen SS, Viken MK, Sollid LM, Lie BA (2014)
    Coeliac disease-associated polymorphisms influence thymic gene expression
    Genes Immun, 15 (6), 355-60
    DOI 10.1038/gene.2014.26, PubMed 24871462
  2. Bergseng E, Dørum S, Arntzen MØ, Nielsen M, Nygård S, Buus S, de Souza GA, Sollid LM (2014)
    Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires
    Immunogenetics, 67 (2), 73-84
    DOI 10.1007/s00251-014-0819-9, PubMed 25502872
  3. Christophersen A, Ráki M, Bergseng E, Lundin KE, Jahnsen J, Sollid LM, Qiao SW (2014)
    Tetramer-visualized gluten-specific CD4+ T cells in blood as a potential diagnostic marker for coeliac disease without oral gluten challenge
    United European Gastroenterol J, 2 (4), 268-78
    DOI 10.1177/2050640614540154, PubMed 25083284
  4. Dørum S, Bodd M, Fallang LE, Bergseng E, Christophersen A, Johannesen MK, Qiao SW, Stamnaes J, de Souza GA, Sollid LM (2014)
    HLA-DQ molecules as affinity matrix for identification of gluten T cell epitopes
    J Immunol, 193 (9), 4497-506
    DOI 10.4049/jimmunol.1301466, PubMed 25261484
  5. Iversen R, Mysling S, Hnida K, Jørgensen TJ, Sollid LM (2014)
    Activity-regulating structural changes and autoantibody epitopes in transglutaminase 2 assessed by hydrogen/deuterium exchange
    Proc Natl Acad Sci U S A, 111 (48), 17146-51
    DOI 10.1073/pnas.1407457111, PubMed 25404341
  6. Jabri B, Chen X, Sollid LM (2014)
    How T cells taste gluten in celiac disease
    Nat Struct Mol Biol, 21 (5), 429-31
    DOI 10.1038/nsmb.2826, PubMed 24777059
  7. Lundin KE, Sollid LM (2014)
    Advances in coeliac disease
    Curr Opin Gastroenterol, 30 (2), 154-62
    DOI 10.1097/MOG.0000000000000041, PubMed 24457347
  8. Sollid LM, Pos W, Wucherpfennig KW (2014)
    Molecular mechanisms for contribution of MHC molecules to autoimmune diseases
    Curr Opin Immunol, 31, 24-30
    DOI 10.1016/j.coi.2014.08.005, PubMed 25216261
  9. Steinsbø Ø, Henry Dunand CJ, Huang M, Mesin L, Salgado-Ferrer M, Lundin KE, Jahnsen J, Wilson PC, Sollid LM (2014)
    Restricted VH/VL usage and limited mutations in gluten-specific IgA of coeliac disease lesion plasma cells
    Nat Commun, 5, 4041
    DOI 10.1038/ncomms5041, PubMed 24909383
  10. Toft-Hansen H, Rasmussen KS, Staal A, Roggen EL, Sollid LM, Lillevang ST, Barington T, Husby S (2014)
    Treatment of both native and deamidated gluten peptides with an endo-peptidase from Aspergillus niger prevents stimulation of gut-derived gluten-reactive T cells from either children or adults with celiac disease
    Clin Immunol, 153 (2), 323-31
    DOI 10.1016/j.clim.2014.05.009, PubMed 24905137

Publications 2013

  1. Bodd M, Ráki M, Bergseng E, Jahnsen J, Lundin KE, Sollid LM (2013)
    Direct cloning and tetramer staining to measure the frequency of intestinal gluten-reactive T cells in celiac disease
    Eur J Immunol, 43 (10), 2605-12
    DOI 10.1002/eji.201343382, PubMed 23775608
  2. Brottveit M, Beitnes AC, Tollefsen S, Bratlie JE, Jahnsen FL, Johansen FE, Sollid LM, Lundin KE (2013)
    Mucosal cytokine response after short-term gluten challenge in celiac disease and non-celiac gluten sensitivity
    Am J Gastroenterol, 108 (5), 842-50
    DOI 10.1038/ajg.2013.91, PubMed 23588237
  3. Iversen R, Di Niro R, Stamnaes J, Lundin KE, Wilson PC, Sollid LM (2013)
    Transglutaminase 2-specific autoantibodies in celiac disease target clustered, N-terminal epitopes not displayed on the surface of cells
    J Immunol, 190 (12), 5981-91
    DOI 10.4049/jimmunol.1300183, PubMed 23690478
  4. Olsen I, Lundin KE, Sollid LM (2013)
    Increased frequency of intestinal CD4+ T cells reactive with mycobacteria in patients with Crohn's disease
    Scand J Gastroenterol, 48 (11), 1278-85
    DOI 10.3109/00365521.2013.837952, PubMed 24131402
  5. Olsen I, Sollid LM (2013)
    Pitfalls in determining the cytokine profile of human T cells
    J Immunol Methods, 390 (1-2), 106-12
    DOI 10.1016/j.jim.2013.01.015, PubMed 23416458
  6. Qiao SW, Christophersen A, Lundin KE, Sollid LM (2013)
    Biased usage and preferred pairing of α- and β-chains of TCRs specific for an immunodominant gluten epitope in coeliac disease
    Int Immunol, 26 (1), 13-9
    DOI 10.1093/intimm/dxt037, PubMed 24038601
  7. Ráki M, Beitnes AC, Lundin KE, Jahnsen J, Jahnsen FL, Sollid LM (2013)
    Plasmacytoid dendritic cells are scarcely represented in the human gut mucosa and are not recruited to the celiac lesion
    Mucosal Immunol, 6 (5), 985-92
    DOI 10.1038/mi.2012.136, PubMed 23340820
  8. Sollid LM, Jabri B (2013)
    Triggers and drivers of autoimmunity: lessons from coeliac disease
    Nat Rev Immunol, 13 (4), 294-302
    DOI 10.1038/nri3407, PubMed 23493116
  9. Sollid LM, Villadangos JA (2013)
    Antigen processing
    Curr Opin Immunol, 25 (1), 71-3
    DOI 10.1016/j.coi.2012.12.002, PubMed 23287556

Publications 2012

  1. Beitnes AC, Ráki M, Brottveit M, Lundin KE, Jahnsen FL, Sollid LM (2012)
    Rapid accumulation of CD14+CD11c+ dendritic cells in gut mucosa of celiac disease after in vivo gluten challenge
    PLoS One, 7 (3), e33556
    DOI 10.1371/journal.pone.0033556, PubMed 22438948
  2. Bodd M, Tollefsen S, Bergseng E, Lundin KE, Sollid LM (2012)
    Evidence that HLA-DQ9 confers risk to celiac disease by presence of DQ9-restricted gluten-specific T cells
    Hum Immunol, 73 (4), 376-81
    DOI 10.1016/j.humimm.2012.01.016, PubMed 22342873
  3. Dafik L, Albertelli M, Stamnaes J, Sollid LM, Khosla C (2012)
    Activation and inhibition of transglutaminase 2 in mice
    PLoS One, 7 (2), e30642
    DOI 10.1371/journal.pone.0030642, PubMed 22319575
  4. Di Niro R, Mesin L, Zheng NY, Stamnaes J, Morrissey M, Lee JH, Huang M, Iversen R, du Pré MF, Qiao SW, Lundin KE, Wilson PC, Sollid LM (2012)
    High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions
    Nat Med, 18 (3), 441-5
    DOI 10.1038/nm.2656, PubMed 22366952
  5. Mesin L, Sollid LM, Di Niro R (2012)
    The intestinal B-cell response in celiac disease
    Front Immunol, 3, 313
    DOI 10.3389/fimmu.2012.00313, PubMed 23060888
  6. Qiao SW, Iversen R, Ráki M, Sollid LM (2012)
    The adaptive immune response in celiac disease
    Semin Immunopathol, 34 (4), 523-40
    DOI 10.1007/s00281-012-0314-z, PubMed 22535446
  7. Sollid LM, Qiao SW, Anderson RP, Gianfrani C, Koning F (2012)
    Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules
    Immunogenetics, 64 (6), 455-60
    DOI 10.1007/s00251-012-0599-z, PubMed 22322673
  8. Tollefsen S, Hotta K, Chen X, Simonsen B, Swaminathan K, Mathews II, Sollid LM, Kim CY (2012)
    Structural and functional studies of trans-encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) protein molecule
    J Biol Chem, 287 (17), 13611-9
    DOI 10.1074/jbc.M111.320374, PubMed 22362761

Publications 2011

  1. Abadie V, Sollid LM, Barreiro LB, Jabri B (2011)
    Integration of genetic and immunological insights into a model of celiac disease pathogenesis
    Annu Rev Immunol, 29, 493-525
    DOI 10.1146/annurev-immunol-040210-092915, PubMed 21219178
  2. Beitnes AC, Ráki M, Lundin KE, Jahnsen J, Sollid LM, Jahnsen FL (2011)
    Density of CD163+ CD11c+ dendritic cells increases and CD103+ dendritic cells decreases in the coeliac lesion
    Scand J Immunol, 74 (2), 186-94
    DOI 10.1111/j.1365-3083.2011.02549.x, PubMed 21392045
  3. Bodd M, Kim CY, Lundin KE, Sollid LM (2011)
    T-cell response to gluten in patients with HLA-DQ2.2 reveals requirement of peptide-MHC stability in celiac disease
    Gastroenterology, 142 (3), 552-61
    DOI 10.1053/j.gastro.2011.11.021, PubMed 22108197
  4. Brottveit M, Ráki M, Bergseng E, Fallang LE, Simonsen B, Løvik A, Larsen S, Løberg EM, Jahnsen FL, Sollid LM, Lundin KE (2011)
    Assessing possible celiac disease by an HLA-DQ2-gliadin Tetramer Test
    Am J Gastroenterol, 106 (7), 1318-24
    DOI 10.1038/ajg.2011.23, PubMed 21364548
  5. Du Pré MF, Kozijn AE, van Berkel LA, ter Borg MN, Lindenbergh-Kortleve D, Jensen LT, Kooy-Winkelaar Y, Koning F, Boon L, Nieuwenhuis EE, Sollid LM, Fugger L, Samsom JN (2011)
    Tolerance to ingested deamidated gliadin in mice is maintained by splenic, type 1 regulatory T cells
    Gastroenterology, 141 (2), 610-20, 620.e1-2
    DOI 10.1053/j.gastro.2011.04.048, PubMed 21683079
  6. du Pré MF, van Berkel LA, Ráki M, van Leeuwen MA, de Ruiter LF, Broere F, Ter Borg MN, Lund FE, Escher JC, Lundin KE, Sollid LM, Kraal G, Nieuwenhuis EE, Samsom JN (2011)
    CD62L(neg)CD38⁺ expression on circulating CD4⁺ T cells identifies mucosally differentiated cells in protein fed mice and in human celiac disease patients and controls
    Am J Gastroenterol, 106 (6), 1147-59
    DOI 10.1038/ajg.2011.24, PubMed 21386831
  7. Halvorsen EH, Strønen E, Hammer HB, Goll GL, Sollid LM, Molberg O (2011)
    Interleukin-15 induces interleukin-17 production by synovial T cell lines from patients with rheumatoid arthritis
    Scand J Immunol, 73 (3), 243-9
    DOI 10.1111/j.1365-3083.2010.02498.x, PubMed 21204897
  8. Jin X, Stamnaes J, Klöck C, DiRaimondo TR, Sollid LM, Khosla C (2011)
    Activation of extracellular transglutaminase 2 by thioredoxin
    J Biol Chem, 286 (43), 37866-73
    DOI 10.1074/jbc.M111.287490, PubMed 21908620
  9. Jüse U, Arntzen M, Højrup P, Fleckenstein B, Sollid LM (2011)
    Assessing high affinity binding to HLA-DQ2.5 by a novel peptide library based approach
    Bioorg Med Chem, 19 (7), 2470-7
    DOI 10.1016/j.bmc.2011.01.057, PubMed 21382721
  10. Mesin L, Di Niro R, Thompson KM, Lundin KE, Sollid LM (2011)
    Long-lived plasma cells from human small intestine biopsies secrete immunoglobulins for many weeks in vitro
    J Immunol, 187 (6), 2867-74
    DOI 10.4049/jimmunol.1003181, PubMed 21841131
  11. Pollmann S, Stensland M, Halvorsen EH, Sollid LM, Kvien TK, Fleckenstein B, Molberg O (2011)
    Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate
    Rheumatol Int, 32 (5), 1271-6
    DOI 10.1007/s00296-010-1765-y, PubMed 21267570
  12. Qiao SW, Ráki M, Gunnarsen KS, Løset GÅ, Lundin KE, Sandlie I, Sollid LM (2011)
    Posttranslational modification of gluten shapes TCR usage in celiac disease
    J Immunol, 187 (6), 3064-71
    DOI 10.4049/jimmunol.1101526, PubMed 21849672
  13. Sollid LM, Jabri B (2011)
    Celiac disease and transglutaminase 2: a model for posttranslational modification of antigens and HLA association in the pathogenesis of autoimmune disorders
    Curr Opin Immunol, 23 (6), 732-8
    DOI 10.1016/j.coi.2011.08.006, PubMed 21917438
  14. Sollid LM, Khosla C (2011)
    Novel therapies for coeliac disease
    J Intern Med, 269 (6), 604-13
    DOI 10.1111/j.1365-2796.2011.02376.x, PubMed 21401739

Publications 2010

  1. Bodd M, Ráki M, Tollefsen S, Fallang LE, Bergseng E, Lundin KE, Sollid LM (2010)
    HLA-DQ2-restricted gluten-reactive T cells produce IL-21 but not IL-17 or IL-22
    Mucosal Immunol, 3 (6), 594-601
    DOI 10.1038/mi.2010.36, PubMed 20571486
  2. Di Niro R, Mesin L, Raki M, Zheng NY, Lund-Johansen F, Lundin KE, Charpilienne A, Poncet D, Wilson PC, Sollid LM (2010)
    Rapid generation of rotavirus-specific human monoclonal antibodies from small-intestinal mucosa
    J Immunol, 185 (9), 5377-83
    DOI 10.4049/jimmunol.1001587, PubMed 20935207
  3. Dørum S, Arntzen MØ, Qiao SW, Holm A, Koehler CJ, Thiede B, Sollid LM, Fleckenstein B (2010)
    The preferred substrates for transglutaminase 2 in a complex wheat gluten digest are Peptide fragments harboring celiac disease T-cell epitopes
    PLoS One, 5 (11), e14056
    DOI 10.1371/journal.pone.0014056, PubMed 21124911
  4. Gil-Humanes J, Pistón F, Tollefsen S, Sollid LM, Barro F (2010)
    Effective shutdown in the expression of celiac disease-related wheat gliadin T-cell epitopes by RNA interference
    Proc Natl Acad Sci U S A, 107 (39), 17023-8
    DOI 10.1073/pnas.1007773107, PubMed 20829492
  5. Jüse U, van de Wal Y, Koning F, Sollid LM, Fleckenstein B (2010)
    Design of new high-affinity peptide ligands for human leukocyte antigen-DQ2 using a positional scanning peptide library
    Hum Immunol, 71 (5), 475-81
    DOI 10.1016/j.humimm.2010.01.021, PubMed 20105447
  6. Stamnaes J, Dorum S, Fleckenstein B, Aeschlimann D, Sollid LM (2010)
    Gluten T cell epitope targeting by TG3 and TG6; implications for dermatitis herpetiformis and gluten ataxia
    Amino Acids, 39 (5), 1183-91
    DOI 10.1007/s00726-010-0554-y, PubMed 20300788
  7. Stamnaes J, Pinkas DM, Fleckenstein B, Khosla C, Sollid LM (2010)
    Redox regulation of transglutaminase 2 activity
    J Biol Chem, 285 (33), 25402-9
    DOI 10.1074/jbc.M109.097162, PubMed 20547769

Publications 2009

  1. Amundsen SS, Rundberg J, Adamovic S, Gudjónsdóttir AH, Ascher H, Ek J, Nilsson S, Lie BA, Naluai AT, Sollid LM (2009)
    Four novel coeliac disease regions replicated in an association study of a Swedish-Norwegian family cohort
    Genes Immun, 11 (1), 79-86
    DOI 10.1038/gene.2009.67, PubMed 19693089
  2. Bethune MT, Crespo-Bosque M, Bergseng E, Mazumdar K, Doyle L, Sestak K, Sollid LM, Khosla C (2009)
    Noninflammatory gluten peptide analogs as biomarkers for celiac sprue
    Chem Biol, 16 (8), 868-81
    DOI 10.1016/j.chembiol.2009.07.009, PubMed 19716477
  3. Dørum S, Qiao SW, Sollid LM, Fleckenstein B (2009)
    A quantitative analysis of transglutaminase 2-mediated deamidation of gluten peptides: implications for the T-cell response in celiac disease
    J Proteome Res, 8 (4), 1748-55
    DOI 10.1021/pr800960n, PubMed 19239248
  4. Fallang LE, Bergseng E, Hotta K, Berg-Larsen A, Kim CY, Sollid LM (2009)
    Differences in the risk of celiac disease associated with HLA-DQ2.5 or HLA-DQ2.2 are related to sustained gluten antigen presentation
    Nat Immunol, 10 (10), 1096-101
    DOI 10.1038/ni.1780, PubMed 19718029
  5. Jabri B, Sollid LM (2009)
    Tissue-mediated control of immunopathology in coeliac disease
    Nat Rev Immunol, 9 (12), 858-70
    DOI 10.1038/nri2670, PubMed 19935805
  6. Olsen I, Tollefsen S, Aagaard C, Reitan LJ, Bannantine JP, Andersen P, Sollid LM, Lundin KE (2009)
    Isolation of Mycobacterium avium subspecies paratuberculosis reactive CD4 T cells from intestinal biopsies of Crohn's disease patients
    PLoS One, 4 (5), e5641
    DOI 10.1371/journal.pone.0005641, PubMed 19479064
  7. Qiao SW, Sollid LM, Blumberg RS (2009)
    Antigen presentation in celiac disease
    Curr Opin Immunol, 21 (1), 111-7
    DOI 10.1016/j.coi.2009.03.004, PubMed 19342211
  8. Stenman SM, Venäläinen JI, Lindfors K, Auriola S, Mauriala T, Kaukovirta-Norja A, Jantunen A, Laurila K, Qiao SW, Sollid LM, Männisto PT, Kaukinen K, Mäki M (2009)
    Enzymatic detoxification of gluten by germinating wheat proteases: implications for new treatment of celiac disease
    Ann Med, 41 (5), 390-400
    DOI 10.1080/07853890902878138, PubMed 19353359
  9. Stensland ME, Pollmann S, Molberg Ø, Sollid LM, Fleckenstein B (2009)
    Primary sequence, together with other factors, influence peptide deimination by peptidylarginine deiminase-4
    Biol Chem, 390 (2), 99-107
    DOI 10.1515/BC.2009.019, PubMed 19040354

Publications 2008

  1. Adamovic S, Amundsen SS, Lie BA, Gudjónsdóttir AH, Ascher H, Ek J, van Heel DA, Nilsson S, Sollid LM, Torinsson Naluai A (2008)
    Association study of IL2/IL21 and FcgRIIa: significant association with the IL2/IL21 region in Scandinavian coeliac disease families
    Genes Immun, 9 (4), 364-7
    DOI 10.1038/gene.2008.27, PubMed 18418394
  2. Bergseng E, Sidney J, Sette A, Sollid LM (2008)
    Analysis of the binding of gluten T-cell epitopes to various human leukocyte antigen class II molecules
    Hum Immunol, 69 (2), 94-100
    DOI 10.1016/j.humimm.2008.01.002, PubMed 18361933
  3. Fallang LE, Roh S, Holm A, Bergseng E, Yoon T, Fleckenstein B, Bandyopadhyay A, Mellins ED, Sollid LM (2008)
    Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM
    J Immunol, 181 (8), 5451-5461
    DOI 10.4049/jimmunol.181.8.5451, PubMed 18832702
  4. Hovhannisyan Z, Weiss A, Martin A, Wiesner M, Tollefsen S, Yoshida K, Ciszewski C, Curran SA, Murray JA, David CS, Sollid LM, Koning F, Teyton L, Jabri B (2008)
    The role of HLA-DQ8 beta57 polymorphism in the anti-gluten T-cell response in coeliac disease
    Nature, 456 (7221), 534-8
    DOI 10.1038/nature07524, PubMed 19037317
  5. Jüse U, Fleckenstein B, Bergseng E, Sollid LM (2008)
    Soluble HLA-DQ2 expressed in S2 cells copurifies with a high affinity insect cell derived protein
    Immunogenetics, 61 (2), 81-9
    DOI 10.1007/s00251-008-0338-7, PubMed 18987854
  6. Qiao SW, Kobayashi K, Johansen FE, Sollid LM, Andersen JT, Milford E, Roopenian DC, Lencer WI, Blumberg RS (2008)
    Dependence of antibody-mediated presentation of antigen on FcRn
    Proc Natl Acad Sci U S A, 105 (27), 9337-42
    DOI 10.1073/pnas.0801717105, PubMed 18599440
  7. Sollid LM (2008)
    Hunting for celiac disease genes
    Gastroenterology, 134 (3), 869-71
    DOI 10.1053/j.gastro.2008.01.020, PubMed 18325395
  8. Sollid LM, Johansen FE (2008)
    Animal models of inflammatory bowel disease at the dawn of the new genetics era
    PLoS Med, 5 (9), e198
    DOI 10.1371/journal.pmed.0050198, PubMed 18828669
  9. Sollid LM, Lundin KE (2008)
    Diagnosis and treatment of celiac disease
    Mucosal Immunol, 2 (1), 3-7
    DOI 10.1038/mi.2008.74, PubMed 19079329
  10. Stamnaes J, Fleckenstein B, Lund-Johansen F, Sollid LM (2008)
    The monoclonal antibody 6B9 recognizes CD44 and not cell surface transglutaminase 2
    Scand J Immunol, 68 (5), 534-42
    DOI 10.1111/j.1365-3083.2008.02173.x, PubMed 18803608
  11. Stamnaes J, Fleckenstein B, Sollid LM (2008)
    The propensity for deamidation and transamidation of peptides by transglutaminase 2 is dependent on substrate affinity and reaction conditions
    Biochim Biophys Acta, 1784 (11), 1804-11
    DOI 10.1016/j.bbapap.2008.08.011, PubMed 18793760
  12. Tunheim G, Schjetne KW, Rasmussen IB, Sollid LM, Sandlie I, Bogen B (2008)
    Recombinant antibodies for delivery of antigen: a single loop between beta-strands in the constant region can accommodate long, complex and tandem T cell epitopes
    Int Immunol, 20 (3), 295-306
    DOI 10.1093/intimm/dxm141, PubMed 18252695

Publications 2007

  1. Adamovic S, Amundsen SS, Lie BA, Hellqvist A, Gudjónsdóttir AH, Ek J, Nilsson S, Wahlström J, Ascher H, Sollid LM, Naluai AT (2007)
    Fine mapping study in Scandinavian families suggests association between coeliac disease and haplotypes in chromosome region 5q32
    Tissue Antigens, 71 (1), 27-34
    DOI 10.1111/j.1399-0039.2007.00955.x, PubMed 17971050
  2. Amundsen SS, Adamovic S, Hellqvist A, Nilsson S, Gudjónsdóttir AH, Ascher H, Ek J, Larsson K, Wahlström J, Lie BA, Sollid LM, Naluai AT (2007)
    A comprehensive screen for SNP associations on chromosome region 5q31-33 in Swedish/Norwegian celiac disease families
    Eur J Hum Genet, 15 (9), 980-7
    DOI 10.1038/sj.ejhg.5201870, PubMed 17551518
  3. Ráki M, Fallang LE, Brottveit M, Bergseng E, Quarsten H, Lundin KE, Sollid LM (2007)
    Tetramer visualization of gut-homing gluten-specific T cells in the peripheral blood of celiac disease patients
    Proc Natl Acad Sci U S A, 104 (8), 2831-6
    DOI 10.1073/pnas.0608610104, PubMed 17307878
  4. Ráki M, Schjetne KW, Stamnaes J, Molberg Ø, Jahnsen FL, Issekutz TB, Bogen B, Sollid LM (2007)
    Surface expression of transglutaminase 2 by dendritic cells and its potential role for uptake and presentation of gluten peptides to T cells
    Scand J Immunol, 65 (3), 213-20
    DOI 10.1111/j.1365-3083.2006.01881.x, PubMed 17309775
  5. Xia J, Bergseng E, Fleckenstein B, Siegel M, Kim CY, Khosla C, Sollid LM (2007)
    Cyclic and dimeric gluten peptide analogues inhibiting DQ2-mediated antigen presentation in celiac disease
    Bioorg Med Chem, 15 (20), 6565-73
    DOI 10.1016/j.bmc.2007.07.001, PubMed 17681795

Publications 2006

  1. Amundsen SS, Monsuur AJ, Wapenaar MC, Lie BA, Ek J, Gudjónsdóttir AH, Ascher H, Wijmenga C, Sollid LM (2006)
    Association analysis of MYO9B gene polymorphisms with celiac disease in a Swedish/Norwegian cohort
    Hum Immunol, 67 (4-5), 341-5
    DOI 10.1016/j.humimm.2006.03.020, PubMed 16720215
  2. Amundsen SS, Vatn M, IBSEN study group, Wijmenga C, Sollid LM, Lie BA (2006)
    Association analysis of MYO9B gene polymorphisms and inflammatory bowel disease in a Norwegian cohort
    Tissue Antigens, 68 (3), 249-52
    DOI 10.1111/j.1399-0039.2006.00665.x, PubMed 16948647
  3. Bethune MT, Strop P, Tang Y, Sollid LM, Khosla C (2006)
    Heterologous expression, purification, refolding, and structural-functional characterization of EP-B2, a self-activating barley cysteine endoprotease
    Chem Biol, 13 (6), 637-47
    DOI 10.1016/j.chembiol.2006.04.008, PubMed 16793521
  4. Bjørnvold M, Amundsen SS, Stene LC, Joner G, Dahl-Jørgensen K, Njølstad PR, Ek J, Ascher H, Gudjònsdòttir AH, Lie BA, Skinningsrud B, Akselsen HE, Rønningen KS, Sollid LM, Undlien DE (2006)
    FOXP3 polymorphisms in type 1 diabetes and coeliac disease
    J Autoimmun, 27 (2), 140-4
    DOI 10.1016/j.jaut.2006.06.007, PubMed 16996248
  5. Holm A, Rise F, Sessler N, Sollid LM, Undheim K, Fleckenstein B (2006)
    Specific modification of peptide-bound citrulline residues
    Anal Biochem, 352 (1), 68-76
    DOI 10.1016/j.ab.2006.02.007, PubMed 16540076
  6. Jabri B, Sollid LM (2006)
    Mechanisms of disease: immunopathogenesis of celiac disease
    Nat Clin Pract Gastroenterol Hepatol, 3 (9), 516-25
    DOI 10.1038/ncpgasthep0582, PubMed 16951668
  7. Molberg Ø, Sollid LM (2006)
    A gut feeling for joint inflammation - using coeliac disease to understand rheumatoid arthritis
    Trends Immunol, 27 (4), 188-94
    DOI 10.1016/j.it.2006.02.006, PubMed 16530013
  8. Ráki M, Tollefsen S, Molberg Ø, Lundin KE, Sollid LM, Jahnsen FL (2006)
    A unique dendritic cell subset accumulates in the celiac lesion and efficiently activates gluten-reactive T cells
    Gastroenterology, 131 (2), 428-38
    DOI 10.1053/j.gastro.2006.06.002, PubMed 16890596
  9. Sollid LM, Vaage JT (2006)
    Cross-dressing T cells go wild
    Nat Med, 12 (6), 611-2
    DOI 10.1038/nm0606-611, PubMed 16761002
  10. Spurkland A, Sollid LM (2006)
    Mapping genes and pathways in autoimmune disease
    Trends Immunol, 27 (7), 336-42
    DOI 10.1016/j.it.2006.05.008, PubMed 16753344
  11. Tollefsen S, Arentz-Hansen H, Fleckenstein B, Molberg O, Ráki M, Kwok WW, Jung G, Lundin KE, Sollid LM (2006)
    HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease
    J Clin Invest, 116 (8), 2226-36
    DOI 10.1172/JCI27620, PubMed 16878175
  12. Xia J, Siegel M, Bergseng E, Sollid LM, Khosla C (2006)
    Inhibition of HLA-DQ2-mediated antigen presentation by analogues of a high affinity 33-residue peptide from alpha2-gliadin
    J Am Chem Soc, 128 (6), 1859-67
    DOI 10.1021/ja056423o, PubMed 16464085

Publications 2005

  1. Bergseng E, Xia J, Kim CY, Khosla C, Sollid LM (2005)
    Main chain hydrogen bond interactions in the binding of proline-rich gluten peptides to the celiac disease-associated HLA-DQ2 molecule
    J Biol Chem, 280 (23), 21791-6
    DOI 10.1074/jbc.M501558200, PubMed 15826953
  2. Fleckenstein B, Qiao SW, Larsen MR, Roepstorff P, Sollid LM, Jung G (2005)
    Molecular characterization of covalent transglutaminase (TG2)-gliadin peptide complexes involved in coeliac disease
    Peptides 2004, Proceedings: BRIDGES BETWEEN DISCIPLINES, 73-74
  3. Khosla C, Gray GM, Sollid LM (2005)
    Putative efficacy and dosage of prolyl endopeptidase for digesting and detoxifying gliadin peptides
    Gastroenterology, 129 (4), 1362-3; author reply 1363
    DOI 10.1053/j.gastro.2005.08.044, PubMed 16230098
  4. Koning F, Schuppan D, Cerf-Bensussan N, Sollid LM (2005)
    Pathomechanisms in celiac disease
    Best Pract Res Clin Gastroenterol, 19 (3), 373-87
    DOI 10.1016/j.bpg.2005.02.003, PubMed 15925843
  5. Molberg O, Uhlen AK, Jensen T, Flaete NS, Fleckenstein B, Arentz-Hansen H, Raki M, Lundin KE, Sollid LM (2005)
    Mapping of gluten T-cell epitopes in the bread wheat ancestors: implications for celiac disease
    Gastroenterology, 128 (2), 393-401
    DOI 10.1053/j.gastro.2004.11.003, PubMed 15685550
  6. Qiao SW, Bergseng E, Molberg O, Jung G, Fleckenstein B, Sollid LM (2005)
    Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: importance of proline spacing and glutamine deamidation
    J Immunol, 175 (1), 254-61
    DOI 10.4049/jimmunol.175.1.254, PubMed 15972656
  7. Qiao SW, Piper J, Haraldsen G, Oynebråten I, Fleckenstein B, Molberg O, Khosla C, Sollid LM (2005)
    Tissue transglutaminase-mediated formation and cleavage of histamine-gliadin complexes: biological effects and implications for celiac disease
    J Immunol, 174 (3), 1657-63
    DOI 10.4049/jimmunol.174.3.1657, PubMed 15661929
  8. Ráki M, Molberg O, Tollefsen S, Lundin KE, Sollid LM (2005)
    The effects of atorvastatin on gluten-induced intestinal T cell responses in coeliac disease
    Clin Exp Immunol, 142 (2), 333-40
    DOI 10.1111/j.1365-2249.2005.02915.x, PubMed 16232221
  9. Shan L, Qiao SW, Arentz-Hansen H, Molberg Ø, Gray GM, Sollid LM, Khosla C (2005)
    Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprue
    J Proteome Res, 4 (5), 1732-41
    DOI 10.1021/pr050173t, PubMed 16212427
  10. Sollid LM (2005)
    Celiac disease as a model of gastrointestinal inflammation
    J Pediatr Gastroenterol Nutr, 40 Suppl 1, S41-2
    PubMed 15805849
  11. Sollid LM, Jabri B (2005)
    Is celiac disease an autoimmune disorder?
    Curr Opin Immunol, 17 (6), 595-600
    DOI 10.1016/j.coi.2005.09.015, PubMed 16214317
  12. Sollid LM, Khosla C (2005)
    Future therapeutic options for celiac disease
    Nat Clin Pract Gastroenterol Hepatol, 2 (3), 140-7
    DOI 10.1038/ncpgasthep0111, PubMed 16265155
  13. Sollid LM, Lie BA (2005)
    Celiac disease genetics: current concepts and practical applications
    Clin Gastroenterol Hepatol, 3 (9), 843-51
    DOI 10.1053/S1542-3565(05)00532-X, PubMed 16234020
  14. Viken MK, Amundsen SS, Kvien TK, Boberg KM, Gilboe IM, Lilleby V, Sollid LM, Førre OT, Thorsby E, Smerdel A, Lie BA (2005)
    Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases
    Genes Immun, 6 (3), 271-3
    DOI 10.1038/sj.gene.6364178, PubMed 15759012
  15. Xia J, Sollid LM, Khosla C (2005)
    Equilibrium and kinetic analysis of the unusual binding behavior of a highly immunogenic gluten peptide to HLA-DQ2
    Biochemistry, 44 (11), 4442-9
    DOI 10.1021/bi047747c, PubMed 15766274

Publications 2004

  1. Amundsen SS, Naluai AT, Ascher H, Ek J, Gudjónsdóttir AH, Wahlström J, Lie BA, Sollid LM (2004)
    Genetic analysis of the CD28/CTLA4/ICOS (CELIAC3) region in coeliac disease
    Tissue Antigens, 64 (5), 593-9
    DOI 10.1111/j.1399-0039.2004.00312.x, PubMed 15496203
  2. Arentz-Hansen H, Fleckenstein B, Molberg Ø, Scott H, Koning F, Jung G, Roepstorff P, Lundin KE, Sollid LM (2004)
    The molecular basis for oat intolerance in patients with celiac disease
    PLoS Med, 1 (1), e1
    DOI 10.1371/journal.pmed.0010001, PubMed 15526039
  3. Fleckenstein B, Qiao SW, Larsen MR, Jung G, Roepstorff P, Sollid LM (2004)
    Molecular characterization of covalent complexes between tissue transglutaminase and gliadin peptides
    J Biol Chem, 279 (17), 17607-16
    DOI 10.1074/jbc.M310198200, PubMed 14747475
  4. Holopainen P, Naluai AT, Moodie S, Percopo S, Coto I, Clot F, Ascher H, Sollid L, Ciclitira P, Greco L, Clerget-Darpoux F, Partanen J, Members of the European Genetics Cluster on Coeliac Disease (2004)
    Candidate gene region 2q33 in European families with coeliac disease
    Tissue Antigens, 63 (3), 212-22
    DOI 10.1111/j.1399-0039.2004.00189.x, PubMed 14989710
  5. Kim CY, Quarsten H, Bergseng E, Khosla C, Sollid LM (2004)
    Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease
    Proc Natl Acad Sci U S A, 101 (12), 4175-9
    DOI 10.1073/pnas.0306885101, PubMed 15020763
  6. Margaritte-Jeannin P, Babron MC, Bourgey M, Louka AS, Clot F, Percopo S, Coto I, Hugot JP, Ascher H, Sollid LM, Greco L, Clerget-Darpoux F (2004)
    HLA-DQ relative risks for coeliac disease in European populations: a study of the European Genetics Cluster on Coeliac Disease
    Tissue Antigens, 63 (6), 562-7
    DOI 10.1111/j.0001-2815.2004.00237.x, PubMed 15140032
  7. Marti T, Molberg O, Li Q, Gray GM, Khosla C, Sollid LM (2004)
    Prolyl endopeptidase-mediated destruction of T cell epitopes in whole gluten: chemical and immunological characterization
    J Pharmacol Exp Ther, 312 (1), 19-26
    DOI 10.1124/jpet.104.073312, PubMed 15358813
  8. Qiao SW, Bergseng E, Molberg Ø, Xia J, Fleckenstein B, Khosla C, Sollid LM (2004)
    Antigen presentation to celiac lesion-derived T cells of a 33-mer gliadin peptide naturally formed by gastrointestinal digestion
    J Immunol, 173 (3), 1757-62
    DOI 10.4049/jimmunol.173.3.1757, PubMed 15265905
  9. Shan L, Marti T, Sollid LM, Gray GM, Khosla C (2004)
    Comparative biochemical analysis of three bacterial prolyl endopeptidases: implications for coeliac sprue
    Biochem J, 383 (Pt 2), 311-8
    DOI 10.1042/BJ20040907, PubMed 15245330
  10. Sollid LM (2004)
    Intraepithelial lymphocytes in celiac disease: license to kill revealed
    Immunity, 21 (3), 303-4
    DOI 10.1016/j.immuni.2004.08.002, PubMed 15357941
  11. Sollid LM, Gray GM (2004)
    A role for bacteria in celiac disease?
    Am J Gastroenterol, 99 (5), 905-6
    DOI 10.1111/j.1572-0241.2004.04158.x, PubMed 15128358

Publications 2003

  1. Babron MC, Nilsson S, Adamovic S, Naluai AT, Wahlström J, Ascher H, Ciclitira PJ, Sollid LM, Partanen J, Greco L, Clerget-Darpoux F, European Genetics Cluster on Coeliac Disease (2003)
    Meta and pooled analysis of European coeliac disease data
    Eur J Hum Genet, 11 (11), 828-34
    DOI 10.1038/sj.ejhg.5201051, PubMed 14571266
  2. Karell K, Louka AS, Moodie SJ, Ascher H, Clot F, Greco L, Ciclitira PJ, Sollid LM, Partanen J, European Genetics Cluster on Celiac Disease (2003)
    HLA types in celiac disease patients not carrying the DQA1*05-DQB1*02 (DQ2) heterodimer: results from the European Genetics Cluster on Celiac Disease
    Hum Immunol, 64 (4), 469-77
    DOI 10.1016/S0198-8859(03)00027-2, PubMed 12651074
  3. Louka AS, Lie BA, Talseth B, Ascher H, Ek J, Gudjónsdóttir AH, Sollid LM (2003)
    Coeliac disease patients carry conserved HLA-DR3-DQ2 haplotypes revealed by association of TNF alleles
    Immunogenetics, 55 (5), 339-43
    DOI 10.1007/s00251-003-0586-5, PubMed 12845502
  4. Louka AS, Moodie SJ, Karell K, Bolognesi E, Ascher H, Greco L, Momigliano-Richiardi P, Partanen J, Ciclitira PJ, Sollid LM, European Genetics Cluster on Celiac Disease (2003)
    A collaborative European search for non-DQA1*05-DQB1*02 celiac disease loci on HLA-DR3 haplotypes: analysis of transmission from homozygous parents
    Hum Immunol, 64 (3), 350-8
    DOI 10.1016/S0198-8859(02)00822-4, PubMed 12590980
  5. Louka AS, Sollid LM (2003)
    HLA in coeliac disease: unravelling the complex genetics of a complex disorder
    Tissue Antigens, 61 (2), 105-17
    DOI 10.1034/j.1399-0039.2003.00017.x, PubMed 12694579
  6. Lundin KE, Farstad IN, Sollid LM (2003)
    [Coeliac disease--new clinical findings and diagnostic tools]
    Tidsskr Nor Laegeforen, 123 (22), 3226-9
    PubMed 14714016
  7. Lundin KE, Sollid LM (2003)
    Gliadin peptide specific intestinal T cells in coeliac disease
    Gut, 52 (2), 162
    DOI 10.1136/gut.52.2.162, PubMed 12524389
  8. Molberg Ø, Solheim Flaete N, Jensen T, Lundin KE, Arentz-Hansen H, Anderson OD, Kjersti Uhlen A, Sollid LM (2003)
    Intestinal T-cell responses to high-molecular-weight glutenins in celiac disease
    Gastroenterology, 125 (2), 337-44
    DOI 10.1016/S0016-5085(03)00890-4, PubMed 12891534
  9. Sollid LM, Lundin KE (2003)
    [Disease mechanisms in coeliac disease]
    Tidsskr Nor Laegeforen, 123 (22), 3230-3
    PubMed 14714017

Publications 2002

  1. Arentz-Hansen H, McAdam SN, Molberg Ø, Fleckenstein B, Lundin KE, Jørgensen TJ, Jung G, Roepstorff P, Sollid LM (2002)
    Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues
    Gastroenterology, 123 (3), 803-9
    DOI 10.1053/gast.2002.35381, PubMed 12198706
  2. Fleckenstein B, Molberg Ø, Qiao SW, Schmid DG, von der Mülbe F, Elgstøen K, Jung G, Sollid LM (2002)
    Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the transamidation versus deamidation process
    J Biol Chem, 277 (37), 34109-16
    DOI 10.1074/jbc.M204521200, PubMed 12093810
  3. Louka AS, Nilsson S, Olsson M, Talseth B, Lie BA, Ek J, Gudjónsdóttir AH, Ascher H, Sollid LM (2002)
    HLA in coeliac disease families: a novel test of risk modification by the 'other' haplotype when at least one DQA1*05-DQB1*02 haplotype is carried
    Tissue Antigens, 60 (2), 147-54
    DOI 10.1034/j.1399-0039.2002.600205.x, PubMed 12392509
  4. Louka AS, Stensby EK, Ek J, Gudjónsdóttir AH, Ascher H, Sollid LM (2002)
    Coeliac disease candidate genes: no association with functional polymorphisms in matrix metalloproteinase 1 and 3 gene promoters
    Scand J Gastroenterol, 37 (8), 931-5
    DOI 10.1080/003655202760230892, PubMed 12229968
  5. Louka AS, Torinsson Naluai A, D'Alfonso S, Ascher H, Coto I, Ek J, Giordano M, Gudjónsdóttir AH, Mellai M, Momigliano-Richiardi P, Percopo S, Samuelsson L, Wahlström J, Greco L, Sollid LM (2002)
    The IL12B gene does not confer susceptibility to coeliac disease
    Tissue Antigens, 59 (1), 70-2
    DOI 10.1034/j.1399-0039.2002.590117.x, PubMed 11972887
  6. Lunde E, Lauvrak V, Rasmussen IB, Schjetne KW, Thompson KM, Michaelsen TE, Brekke OH, Sollid LM, Bogen B, Sandlie I (2002)
    Troybodies and pepbodies
    Biochem Soc Trans, 30 (4), 500-6
    DOI 10.1042/, PubMed 12196123
  7. Schjetne KW, Thompson KM, Aarvak T, Fleckenstein B, Sollid LM, Bogen B (2002)
    A mouse C kappa-specific T cell clone indicates that DC-SIGN is an efficient target for antibody-mediated delivery of T cell epitopes for MHC class II presentation
    Int Immunol, 14 (12), 1423-30
    DOI 10.1093/intimm/dxf110, PubMed 12456590
  8. Shan L, Molberg Ø, Parrot I, Hausch F, Filiz F, Gray GM, Sollid LM, Khosla C (2002)
    Structural basis for gluten intolerance in celiac sprue
    Science, 297 (5590), 2275-9
    DOI 10.1126/science.1074129, PubMed 12351792
  9. Sollid LM (2002)
    Coeliac disease: dissecting a complex inflammatory disorder
    Nat Rev Immunol, 2 (9), 647-55
    DOI 10.1038/nri885, PubMed 12209133
  10. Sollid LM (2002)
    Breast milk against coeliac disease
    Gut, 51 (6), 767-8
    DOI 10.1136/gut.51.6.767, PubMed 12427772

Publications 2001

  1. McAdam SN, Fleckenstein B, Rasmussen IB, Schmid DG, Sandlie I, Bogen B, Viner NJ, Sollid LM (2001)
    T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation
    J Exp Med, 193 (11), 1239-46
    DOI 10.1084/jem.193.11.1239, PubMed 11390431
  2. Molberg O, McAdam S, Lundin KE, Kristiansen C, Arentz-Hansen H, Kett K, Sollid LM (2001)
    T cells from celiac disease lesions recognize gliadin epitopes deamidated in situ by endogenous tissue transglutaminase
    Eur J Immunol, 31 (5), 1317-23
    DOI 10.1002/1521-4141(200105)31:5<1317::AID-IMMU1317>3.0.CO;2-I, PubMed 11465088
  3. Naluai AT, Nilsson S, Gudjónsdóttir AH, Louka AS, Ascher H, Ek J, Hallberg B, Samuelsson L, Kristiansson B, Martinsson T, Nerman O, Sollid LM, Wahlström J (2001)
    Genome-wide linkage analysis of Scandinavian affected sib-pairs supports presence of susceptibility loci for celiac disease on chromosomes 5 and 11
    Eur J Hum Genet, 9 (12), 938-44
    DOI 10.1038/sj.ejhg.5200752, PubMed 11840196
  4. Quarsten H, McAdam SN, Jensen T, Arentz-Hansen H, Molberg Ø, Lundin KE, Sollid LM (2001)
    Staining of celiac disease-relevant T cells by peptide-DQ2 multimers
    J Immunol, 167 (9), 4861-8
    DOI 10.4049/jimmunol.167.9.4861, PubMed 11673490
  5. Sollid LM, Lundin KE (2001)
    Coeliac disease. An inappropriate immune response
    Lancet, 358 Suppl, S13
    PubMed 11784562
  6. Sollid LM, McAdam SN, Molberg O, Quarsten H, Arentz-Hansen H, Louka AS, Lundin KE (2001)
    Genes and environment in celiac disease
    Acta Odontol Scand, 59 (3), 183-6
    DOI 10.1080/000163501750266792, PubMed 11501889

Publications 2000

  1. Arentz-Hansen EH, McAdam SN, Molberg O, Kristiansen C, Sollid LM (2000)
    Production of a panel of recombinant gliadins for the characterisation of T cell reactivity in coeliac disease
    Gut, 46 (1), 46-51
    DOI 10.1136/gut.46.1.46, PubMed 10601054
  2. Arentz-Hansen H, Körner R, Molberg O, Quarsten H, Vader W, Kooy YM, Lundin KE, Koning F, Roepstorff P, Sollid LM, McAdam SN (2000)
    The intestinal T cell response to alpha-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase
    J Exp Med, 191 (4), 603-12
    DOI 10.1084/jem.191.4.603, PubMed 10684852
  3. McAdam SN, Sollid LM (2000)
    Getting to grips with gluten
    Gut, 47 (6), 743-5
    DOI 10.1136/gut.47.6.743, PubMed 11076867
  4. Molberg O, McAdam SN, Lundin KE, Sollid LM (2000)
    Studies of gliadin-specific T-cells in celiac disease
    Methods Mol Med, 41, 105-24
    DOI 10.1385/1-59259-082-9:105, PubMed 21374436
  5. Molberg O, McAdam SN, Sollid LM (2000)
    Role of tissue transglutaminase in celiac disease
    J Pediatr Gastroenterol Nutr, 30 (3), 232-40
    DOI 10.1097/00005176-200003000-00005, PubMed 10749404
  6. Naluai AT, Nilsson S, Samuelsson L, Gudjónsdóttir AH, Ascher H, Ek J, Hallberg B, Kristiansson B, Martinsson T, Nerman O, Sollid LM, Wahlström J (2000)
    The CTLA4/CD28 gene region on chromosome 2q33 confers susceptibility to celiac disease in a way possibly distinct from that of type 1 diabetes and other chronic inflammatory disorders
    Tissue Antigens, 56 (4), 350-5
    PubMed 11098935
  7. Sollid LM (2000)
    Molecular basis of celiac disease
    Annu Rev Immunol, 18, 53-81
    DOI 10.1146/annurev.immunol.18.1.53, PubMed 10837052

Publications 1999

  1. Lie BA, Sollid LM, Ascher H, Ek J, Akselsen HE, Rønningen KS, Thorsby E, Undlien DE (1999)
    A gene telomeric of the HLA class I region is involved in predisposition to both type 1 diabetes and coeliac disease
    Tissue Antigens, 54 (2), 162-8
    DOI 10.1034/j.1399-0039.1999.540207.x, PubMed 10488743
  2. Quarsten H, Molberg O, Fugger L, McAdam SN, Sollid LM (1999)
    HLA binding and T cell recognition of a tissue transglutaminase-modified gliadin epitope
    Eur J Immunol, 29 (8), 2506-14
    DOI 10.1002/(SICI)1521-4141(199908)29:08<2506::AID-IMMU2506>3.0.CO;2-9, PubMed 10458765

Publications 1998

  1. Haraldsen G, Sollid LM, Bakke O, Farstad IN, Kvale D, Molberg, Norstein J, Stang E, Brandtzaeg P (1998)
    Major histocompatibility complex class II-dependent antigen presentation by human intestinal endothelial cells
    Gastroenterology, 114 (4), 649-56
    DOI 10.1016/S0016-5085(98)70578-5, PubMed 9516385
  2. Molberg O, Lundin KE, Nilsen EM, Scott H, Kett K, Brandtzaeg P, Thorsby E, Sollid LM (1998)
    HLA restriction patterns of gliadin- and astrovirus-specific CD4+ T cells isolated in parallel from the small intestine of celiac disease patients
    Tissue Antigens, 52 (5), 407-15
    DOI 10.1111/j.1399-0039.1998.tb03066.x, PubMed 9864029
  3. Molberg O, Mcadam SN, Körner R, Quarsten H, Kristiansen C, Madsen L, Fugger L, Scott H, Norén O, Roepstorff P, Lundin KE, Sjöström H, Sollid LM (1998)
    Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease
    Nat Med, 4 (6), 713-7
    DOI 10.1038/nm0698-713, PubMed 9623982
  4. Molberg O, Nilsen EM, Sollid LM, Scott H, Brandtzaeg P, Thorsby E, Lundin KE (1998)
    CD4+ T cells with specific reactivity against astrovirus isolated from normal human small intestine
    Gastroenterology, 114 (1), 115-22
    DOI 10.1016/S0016-5085(98)70639-0, PubMed 9428225
  5. Nilsen EM, Jahnsen FL, Lundin KE, Johansen FE, Fausa O, Sollid LM, Jahnsen J, Scott H, Brandtzaeg P (1998)
    Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease
    Gastroenterology, 115 (3), 551-63
    DOI 10.1016/S0016-5085(98)70134-9, PubMed 9721152
  6. Quarsten H, Paulsen G, Johansen BH, Thorpe CJ, Holm A, Buus S, Sollid LM (1998)
    The P9 pocket of HLA-DQ2 (non-Aspbeta57) has no particular preference for negatively charged anchor residues found in other type 1 diabetes-predisposing non-Aspbeta57 MHC class II molecules
    Int Immunol, 10 (8), 1229-36
    DOI 10.1093/intimm/10.8.1229, PubMed 9723710
  7. Sjöström H, Lundin KE, Molberg O, Körner R, McAdam SN, Anthonsen D, Quarsten H, Norén O, Roepstorff P, Thorsby E, Sollid LM (1998)
    Identification of a gliadin T-cell epitope in coeliac disease: general importance of gliadin deamidation for intestinal T-cell recognition
    Scand J Immunol, 48 (2), 111-5
    PubMed 9716100
  8. Sollid LM (1998)
    Genetics of the immune response to gluten in coeliac disease
    Dig Dis, 16 (6), 345-7
    DOI 10.1159/000016889, PubMed 10207220
  9. Sollid LM, Scott H (1998)
    New tool to predict celiac disease on its way to the clinics
    Gastroenterology, 115 (6), 1584-6
    DOI 10.1016/S0016-5085(98)70040-X, PubMed 9834289
  10. Straumfors A, Johansen BH, Vartdal F, Sollid LM, Thorsby E, Buus S (1998)
    A peptide-binding assay for the disease-associated HLA-DQ8 molecule
    Scand J Immunol, 47 (6), 561-7
    PubMed 9652824
  11. van de Wal Y, Kooy YM, van Veelen PA, Peña SA, Mearin LM, Molberg O, Lundin KE, Sollid LM, Mutis T, Benckhuijsen WE, Drijfhout JW, Koning F (1998)
    Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin
    Proc Natl Acad Sci U S A, 95 (17), 10050-4
    DOI 10.1073/pnas.95.17.10050, PubMed 9707598

Publications 1997

  1. Lundin KE, Sollid LM, Anthonsen D, Norén O, Molberg O, Thorsby E, Sjöström H (1997)
    Heterogeneous reactivity patterns of HLA-DQ-restricted, small intestinal T-cell clones from patients with celiac disease
    Gastroenterology, 112 (3), 752-9
    DOI 10.1053/gast.1997.v112.pm9041236, PubMed 9041236
  2. Molberg O, Kett K, Scott H, Thorsby E, Sollid LM, Lundin KE (1997)
    Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls
    Scand J Immunol, 46 (1), 103-8
    DOI 10.1046/j.1365-3083.1997.d01-93.x, PubMed 9246215
  3. Molberg O, Kett K, Scott H, Thorsby E, Sollid LM, Lundin KE (1997)
    Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls
    Scand J Immunol, 46 (3), 103-9
    DOI 10.1046/j.1365-3083.1997.d01-93.x, PubMed 9315123
  4. Scott H, Nilsen E, Sollid LM, Lundin KE, Rugtveit J, Molberg O, Thorsby E, Brandtzaeg P (1997)
    Immunopathology of gluten-sensitive enteropathy
    Springer Semin Immunopathol, 18 (4), 535-53
    DOI 10.1007/BF00824057, PubMed 9144869
  5. Sollid LM, Molberg O, McAdam S, Lundin KE (1997)
    Autoantibodies in coeliac disease: tissue transglutaminase--guilt by association?
    Gut, 41 (6), 851-2
    DOI 10.1136/gut.41.6.851, PubMed 9462222
  6. Spurkland A, Ingvarsson G, Falk ES, Knutsen I, Sollid LM, Thorsby E (1997)
    Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA-DQ (alpha 1*0501, beta 1*02) or the HLA-DQ (alpha 1*03, beta 1*0302) heterodimers
    Tissue Antigens, 49 (1), 29-34
    DOI 10.1111/j.1399-0039.1997.tb02706.x, PubMed 9027962

Publications 1996

  1. Johansen BH, Gjertsen HA, Vartdal F, Buus S, Thorsby E, Lundin KE, Sollid LM (1996)
    Binding of peptides from the N-terminal region of alpha-gliadin to the celiac disease-associated HLA-DQ2 molecule assessed in biochemical and T cell assays
    Clin Immunol Immunopathol, 79 (3), 288-93
    DOI 10.1006/clin.1996.0081, PubMed 8635288
  2. Johansen BH, Jensen T, Thorpe CJ, Vartdal F, Thorsby E, Sollid LM (1996)
    Both alpha and beta chain polymorphisms determine the specificity of the disease-associated HLA-DQ2 molecules, with beta chain residues being most influential
    Immunogenetics, 45 (2), 142-50
    DOI 10.1007/s002510050182, PubMed 8952964
  3. Johansen BH, Vartdal F, Eriksen JA, Thorsby E, Sollid LM (1996)
    Identification of a putative motif for binding of peptides to HLA-DQ2
    Int Immunol, 8 (2), 177-82
    DOI 10.1093/intimm/8.2.177, PubMed 8671602
  4. Ploski R, Ascher H, Sollid LM (1996)
    HLA genotypes and the increased incidence of coeliac disease in Sweden
    Scand J Gastroenterol, 31 (11), 1092-7
    DOI 10.3109/00365529609036892, PubMed 8938902
  5. Vartdal F, Johansen BH, Friede T, Thorpe CJ, Stevanović S, Eriksen JE, Sletten K, Thorsby E, Rammensee HG, Sollid LM (1996)
    The peptide binding motif of the disease associated HLA-DQ (alpha 1* 0501, beta 1* 0201) molecule
    Eur J Immunol, 26 (11), 2764-72
    DOI 10.1002/eji.1830261132, PubMed 8921967

Publications 1995

  1. Jensen K, Sollid LM, Scott H, Paulsen G, Kett K, Thorsby E, Lundin KE (1995)
    Gliadin-specific T cell responses in peripheral blood of healthy individuals involve T cells restricted by the coeliac disease associated DQ2 heterodimer
    Scand J Immunol, 42 (1), 166-70
    DOI 10.1111/j.1365-3083.1995.tb03640.x, PubMed 7543212
  2. Mignot E, Kimura A, Abbal M, Thorsby E, Lin X, Voros A, Macaubas C, Bouissou F, Sollid LM, Cambon-Thomsen A (1995)
    DQCAR microsatellite polymorphisms in three selected HLA class II-associated diseases
    Tissue Antigens, 46 (4), 299-304
    DOI 10.1111/j.1399-0039.1995.tb02496.x, PubMed 8560448
  3. Nilsen EM, Lundin KE, Krajci P, Scott H, Sollid LM, Brandtzaeg P (1995)
    Gluten specific, HLA-DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or Th0 profile dominated by interferon gamma
    Gut, 37 (6), 766-76
    DOI 10.1136/gut.37.6.766, PubMed 8537046
  4. Paulsen G, Lundin KE, Gjertsen HA, Hansen T, Sollid LM, Thorsby E (1995)
    HLA-DQ2-restricted T-cell recognition of gluten-derived peptides in celiac disease. Influence of amino acid substitutions in the membrane distal domain of DQ beta 1*0201
    Hum Immunol, 42 (2), 145-53
    DOI 10.1016/0198-8859(94)00086-6, PubMed 7744618
  5. Przemioslo RT, Lundin KE, Sollid LM, Nelufer J, Ciclitira PJ (1995)
    Histological changes in small bowel mucosa induced by gliadin sensitive T lymphocytes can be blocked by anti-interferon gamma antibody
    Gut, 36 (6), 874-9
    DOI 10.1136/gut.36.6.874, PubMed 7615276
  6. Viken HD, Paulsen G, Drover S, Marshall WH, Sollid LM, Gaudernack G, Thorsby E (1995)
    Influence on antibody recognition of amino acid substitutions in the cleft of HLA-DQ2 molecules. Suggestive evidence of peptide-dependent epitopes
    Hum Immunol, 44 (2), 63-9
    DOI 10.1016/0198-8859(95)00047-8, PubMed 8847230
  7. Viken HD, Paulsen G, Sollid LM, Lundin KE, Tjønnfjord GE, Thorsby E, Gaudernack G (1995)
    Characterization of an HLA-DQ2-specific monoclonal antibody. Influence of amino acid substitutions in DQ beta 1*0202
    Hum Immunol, 42 (4), 319-27
    DOI 10.1016/0198-8859(94)00110-C, PubMed 7558917

Publications 1994

  1. Gjertsen HA, Lundin KE, Sollid LM, Eriksen JA, Thorsby E (1994)
    T cells recognize a peptide derived from alpha-gliadin presented by the celiac disease-associated HLA-DQ (alpha 1*0501, beta 1*0201) heterodimer
    Hum Immunol, 39 (4), 243-52
    DOI 10.1016/0198-8859(94)90267-4, PubMed 7520895
  2. Gjertsen HA, Sollid LM, Ek J, Thorsby E, Lundin KE (1994)
    T cells from the peripheral blood of coeliac disease patients recognize gluten antigens when presented by HLA-DR, -DQ, or -DP molecules
    Scand J Immunol, 39 (6), 567-74
    DOI 10.1111/j.1365-3083.1994.tb03414.x, PubMed 8009173
  3. Johansen BH, Buus S, Vartdal F, Viken H, Eriksen JA, Thorsby E, Sollid LM (1994)
    Binding of peptides to HLA-DQ molecules: peptide binding properties of the disease-associated HLA-DQ(alpha 1*0501, beta 1*0201) molecule
    Int Immunol, 6 (3), 453-61
    DOI 10.1093/intimm/6.3.453, PubMed 8186196
  4. Johansen BH, Gedde-Dahl T, Sollid LM, Vartdal F, Thorsby E, Gaudernack G (1994)
    Binding of ras oncogene peptides to purified HLA-DQ(alpha 1*0102,beta 1*0602) and -DR(alpha,beta 1*0101) molecules
    Scand J Immunol, 39 (6), 607-12
    DOI 10.1111/j.1365-3083.1994.tb03420.x, PubMed 8009176
  5. Johansen BH, Gedde-Dahl T, Sollid LM, Vartdal F, Thorsby E, Gaudernack G (1994)
    Binding of ras oncogene peptides to purified HLA-DQ (alpha 1*0102, beta 1*0602) and -DR (alpha, beta 1*0101) molecules
    Scand J Immunol, 40 (4), 468
    PubMed 7939420
  6. Lundin KE, Gjertsen HA, Scott H, Sollid LM, Thorsby E (1994)
    Function of DQ2 and DQ8 as HLA susceptibility molecules in celiac disease
    Hum Immunol, 41 (1), 24-7
    DOI 10.1016/0198-8859(94)90079-5, PubMed 7836060
  7. Lundin KE, Scott H, Fausa O, Thorsby E, Sollid LM (1994)
    T cells from the small intestinal mucosa of a DR4, DQ7/DR4, DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8
    Hum Immunol, 41 (4), 285-91
    DOI 10.1016/0198-8859(94)90047-7, PubMed 7883596

Publications 1993

  1. Lundin KE, Scott H, Hansen T, Paulsen G, Halstensen TS, Fausa O, Thorsby E, Sollid LM (1993)
    Gliadin-specific, HLA-DQ(alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients
    J Exp Med, 178 (1), 187-96
    DOI 10.1084/jem.178.1.187, PubMed 8315377
  2. Ploski R, Ek J, Thorsby E, Sollid LM (1993)
    On the HLA-DQ(alpha 1*0501, beta 1*0201)-associated susceptibility in celiac disease: a possible gene dosage effect of DQB1*0201
    Tissue Antigens, 41 (4), 173-7
    DOI 10.1111/j.1399-0039.1993.tb01998.x, PubMed 8362409
  3. Sollid LM, Thorsby E (1993)
    HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis
    Gastroenterology, 105 (3), 910-22
    DOI 10.1016/0016-5085(93)90912-V, PubMed 8359659

Publications 1992

  1. Spurkland A, Sollid LM, Polanco I, Vartdal F, Thorsby E (1992)
    HLA-DR and -DQ genotypes of celiac disease patients serologically typed to be non-DR3 or non-DR5/7
    Hum Immunol, 35 (3), 188-92
    PubMed 1293082
  2. Thrane PS, Sollid LM, Haanes HR, Brandtzaeg P (1992)
    Clustering of IgA-producing immunocytes related to HLA-DR-positive ducts in normal and inflamed salivary glands
    Scand J Immunol, 35 (1), 43-51
    DOI 10.1111/j.1365-3083.1992.tb02832.x, PubMed 1734495

Publications 1991

  1. Brandtzaeg P, Bengtsson U, Halstensen TS, Hvatum M, Kett K, Rognum TO, Scott H, Sollid LM (1991)
    Mucosal immunology and food antigens
    Bibl Nutr Dieta (48), 30-54
    PubMed 1930122
  2. Ronningen KS, Spurkland A, Iwe T, Sollid LM, Vartdal F, Thorsby E (1991)
    Novel HLA-DR2 and -DR3 haplotypes among Norwegian Caucasians
    Tissue Antigens, 37 (4), 165-7
    PubMed 1926125

Publications 1990

  1. Lundin KE, Sollid LM, Bosnes V, Gaudernack G, Thorsby E (1990)
    T-cell recognition of HLA class II molecules induced by gamma-interferon on a colonic adenocarcinoma cell line (HT29)
    Scand J Immunol, 31 (4), 469-75
    DOI 10.1111/j.1365-3083.1990.tb02794.x, PubMed 2110380
  2. Lundin KE, Sollid LM, Qvigstad E, Markussen G, Gjertsen HA, Ek J, Thorsby E (1990)
    T lymphocyte recognition of a celiac disease-associated cis- or trans-encoded HLA-DQ alpha/beta-heterodimer
    J Immunol, 145 (1), 136-9
    PubMed 1972714
  3. Sollid LM, Thorsby E (1990)
    The primary association of celiac disease to a given HLA-DQ alpha/beta heterodimer explains the divergent HLA-DR associations observed in various Caucasian populations
    Tissue Antigens, 36 (3), 136-7
    DOI 10.1111/j.1399-0039.1990.tb01816.x, PubMed 2278049
  4. Spurkland A, Sollid LM, Rønningen KS, Bosnes V, Ek J, Vartdal F, Thorsby E (1990)
    Susceptibility to develop celiac disease is primarily associated with HLA-DQ alleles
    Hum Immunol, 29 (3), 157-65
    DOI 10.1016/0198-8859(90)90111-2, PubMed 1980918
  5. Thrane PS, Roop DR, Sollid LM, Huitfeldt HS, Brandtzaeg P (1990)
    Two-colour immunofluorescence marker study of pleomorphic adenomas
    Histochemistry, 93 (5), 459-68
    PubMed 2158957
  6. Thrane PS, Sollid LM, Brandtzaeg P (1990)
    Abundant dendritic cells express HLA-DR in pleomorphic adenomas
    Virchows Arch B Cell Pathol Incl Mol Pathol, 59 (4), 195-203
    DOI 10.1007/BF02899405, PubMed 1980169

Publications 1989

  1. Brandtzaeg P, Bosnes V, Halstensen TS, Scott H, Sollid LM, Valnes KN (1989)
    T lymphocytes in human gut epithelium preferentially express the alpha/beta antigen receptor and are often CD45/UCHL1-positive
    Scand J Immunol, 30 (1), 123-8
    PubMed 2526965
  2. Brandtzaeg P, Halstensen TS, Kett K, Krajci P, Kvale D, Rognum TO, Scott H, Sollid LM (1989)
    Immunobiology and immunopathology of human gut mucosa: humoral immunity and intraepithelial lymphocytes
    Gastroenterology, 97 (6), 1562-84
    DOI 10.1016/0016-5085(89)90406-X, PubMed 2684725
  3. Lundin KE, Ovigstad E, Sollid LM, Gjertsen HA, Gaudernack G, Thorsby E (1989)
    Positive selection of Tac- (CD25) positive cells following T-cell activation. Use of immunomagnetic separation and implications for T-cell cloning
    J Immunogenet, 16 (2), 185-91
    PubMed 2687389
  4. Lundin KE, Qvigstad E, Sollid LM, Thorsby E (1989)
    Alloreactive T cells recognizing determinants dependent on the DQ beta chain of DQw2
    Tissue Antigens, 34 (5), 312-6
    DOI 10.1111/j.1399-0039.1989.tb01748.x, PubMed 2483467
  5. Sollid LM, Markussen G, Ek J, Gjerde H, Vartdal F, Thorsby E (1989)
    Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer
    J Exp Med, 169 (1), 345-50
    DOI 10.1084/jem.169.1.345, PubMed 2909659
  6. Thorsby E, Lundin KE, Rønningen KS, Sollid LM, Vartdal F (1989)
    Molecular basis and functional importance of some disease-associated HLA polymorphisms
    Tissue Antigens, 34 (1), 39-49
    DOI 10.1111/j.1399-0039.1989.tb01716.x, PubMed 2683208
  7. Vartdal F, Rønningen KS, Sollid LM, Thorsby E (1989)
    [Gene technology in immunologic research, diagnosis and treatment]
    Tidsskr Nor Laegeforen, 109 (30), 3111-4
    PubMed 2683198
  8. Vartdal F, Sollid LM, Vandvik B, Markussen G, Thorsby E (1989)
    Patients with multiple sclerosis carry DQB1 genes which encode shared polymorphic amino acid sequences
    Hum Immunol, 25 (2), 103-10
    DOI 10.1016/0198-8859(89)90074-8, PubMed 2737928

Publications 1988

  1. Brandtzaeg P, Kvale D, Sollid LM, Thrane PS (1988)
    The poly-Ig receptor--functional aspects of secretory component expression
    Adv Exp Med Biol, 237, 9-20
    PubMed 3151046
  2. Brandtzaeg P, Sollid LM, Bjerke K, Kett K, Kvale D, Rognum TO, Scott H, Thrane PS (1988)
    Interactions of lymphoid cells with the epithelial environment
    Monogr Allergy, 24, 51-9
    PubMed 3163099
  3. Brandtzaeg P, Sollid LM, Thrane PS, Kvale D, Bjerke K, Scott H, Kett K, Rognum TO (1988)
    Lymphoepithelial interactions in the mucosal immune system
    Gut, 29 (8), 1116-30
    DOI 10.1136/gut.29.8.1116, PubMed 3044933
  4. Kvale D, Bartek J, Sollid LM, Brandtzaeg P (1988)
    Rapid selection of cultured cells with increased expression of a membrane marker (secretory component)
    Int J Cancer, 42 (4), 638-41
    DOI 10.1002/ijc.2910420428, PubMed 2459074
  5. Kvale D, Løvhaug D, Sollid LM, Brandtzaeg P (1988)
    Tumor necrosis factor-alpha up-regulates expression of secretory component, the epithelial receptor for polymeric Ig
    J Immunol, 140 (9), 3086-9
    PubMed 3361127
  6. Lundin KE, Gaudernack G, Qvigstad E, Sollid LM, Thorsby E (1988)
    T lymphocyte clones recognizing an HLA-DQw3.2-associated epitope involving residue 57 on the DQ beta chain
    Hum Immunol, 22 (4), 235-46
    PubMed 2459088
  7. Markussen G, Rønningen KS, Paulsen G, Gaudernack G, Sollid LM, Thorsby E (1988)
    HLA-DQw3.1 and DQw3.2 associated exon polymorphisms detected by oligonucleotide probes
    Tissue Antigens, 31 (4), 204-10
    DOI 10.1111/j.1399-0039.1988.tb02082.x, PubMed 3406934
  8. Scott H, Sollid LM, Brandtzaeg P (1988)
    Expression of MHC class II determinants by jejunal epithelium in coeliac disease
    J Pediatr Gastroenterol Nutr, 7 (1), 145-6
    DOI 10.1097/00005176-198801000-00027, PubMed 3335977
  9. Scott H, Sollid LM, Brandtzaeg P, Thorsby E (1988)
    Jejunal epithelium of patients with coeliac disease shows enhanced expression of MHC class II subregion products
    Adv Exp Med Biol, 237, 689-93
    PubMed 3075870
  10. Sollid LM, Brandtzaeg P, Kvale D, Gaudernack G, Scott H, Thorsby E (1988)
    T cell-epithelium interactions in relation to gut immunity
    Monogr Allergy, 24, 60-5
    PubMed 3129651
  11. Sollid LM, Thrane PS, Brandtzaeg P (1988)
    [Cancer and immune defense]
    Tidsskr Nor Laegeforen, 108 (15), 1205-9
    PubMed 3291190

Publications 1987

  1. Brandtzaeg P, Bjerke K, Kett K, Kvale D, Rognum TO, Scott H, Sollid LM, Valnes K (1987)
    Production and secretion of immunoglobulins in the gastrointestinal tract
    Ann Allergy, 59 (5 Pt 2), 21-39
    PubMed 3318585
  2. Kolberg J, Wedege E, Sollid L (1987)
    Immunoblotting detection of lectins in gluten and white rice flour
    Biochem Biophys Res Commun, 142 (3), 717-23
    DOI 10.1016/0006-291X(87)91473-2, PubMed 3827897
  3. Paulsen G, Markussen G, Sollid L, Thorsby E (1987)
    Determination of the HLA-DR profile of an HLA class II negative carcinoma cell line by restriction fragment length polymorphism (RFLP) analysis
    Tissue Antigens, 29 (4), 186-94
    PubMed 2887045
  4. Scott H, Sollid LM, Fausa O, Brandtzaeg P, Thorsby E (1987)
    Expression of major histocompatibility complex class II subregion products by jejunal epithelium in patients with coeliac disease
    Scand J Immunol, 26 (5), 563-71
    DOI 10.1111/j.1365-3083.1987.tb02290.x, PubMed 3500504
  5. Sollid L, Paulsen G, Gaudernack G, Thorsby E (1987)
    HLA class II profile of a human carcinoma cell line: detection on genomic level and after exposure to gamma-interferon
    Transplant Proc, 19 (1 Pt 1), 215
    PubMed 3152692
  6. Sollid LM, Gaudernack G, Markussen G, Kvale D, Brandtzaeg P, Thorsby E (1987)
    Induction of various HLA class II molecules in a human colonic adenocarcinoma cell line
    Scand J Immunol, 25 (2), 175-80
    DOI 10.1111/j.1365-3083.1987.tb01061.x, PubMed 2434988
  7. Sollid LM, Kvale D, Brandtzaeg P, Markussen G, Thorsby E (1987)
    Synthesis of cytoplasmic and functional membrane SC induced by gamma-interferon
    Adv Exp Med Biol, 216B, 1109-16
    PubMed 3122531
  8. Sollid LM, Kvale D, Brandtzaeg P, Markussen G, Thorsby E (1987)
    Interferon-gamma enhances expression of secretory component, the epithelial receptor for polymeric immunoglobulins
    J Immunol, 138 (12), 4303-6
    PubMed 3108385
  9. Thrane PS, Sollid LM, Huitfeldt H, Brandtzaeg P (1987)
    Pleomorphic adenomas contain a keratin-negative population of HLA-DR-positive dendritic cells
    Adv Exp Med Biol, 216A, 437-44
    PubMed 2446470

Publications 1986

  1. Bruserud O, Sollid L, Gaudernack G, Thorsby E (1986)
    The role of the CD8-positive subset of T cells in proliferative responses to soluble antigens. II. CD8-positive cells are not responsible for DR-associated differences in responsiveness to mumps and Coxsackie B4
    Scand J Immunol, 23 (4), 469-73
    PubMed 3010444
  2. Bruserud O, Sollid L, Jørgensen PF (1986)
    The proliferative T-lymphocyte response to streptokinase
    J Clin Lab Immunol, 20 (2), 69-74
    PubMed 2942694
  3. Sollid L, Bruserud O, Gaudernack G, Thorsby E (1986)
    The role of the CD8-positive subset of T cells in proliferative responses to soluble antigens. I. Studies of healthy subjects, type 1 diabetics, and coeliac disease patients
    Scand J Immunol, 23 (4), 461-7
    PubMed 3010443
  4. Sollid LM, Kolberg J, Scott H, Ek J, Fausa O, Brandtzaeg P (1986)
    Antibodies to wheat germ agglutinin in coeliac disease
    Clin Exp Immunol, 63 (1), 95-100
    PubMed 3754186
  5. Sollid LM, Scott H, Kolberg J, Brandtzaeg P (1986)
    Serum antibodies to wheat germ agglutinin and gluten in patients with dermatitis herpetiformis
    Arch Dermatol Res, 278 (6), 433-6
    DOI 10.1007/BF00455158, PubMed 3789802

Publications 1985

  1. Kolberg J, Sollid L (1985)
    Lectin activity of gluten identified as wheat germ agglutinin
    Biochem Biophys Res Commun, 130 (2), 867-72
    DOI 10.1016/0006-291X(85)90496-6, PubMed 3839672
  2. SOLLID L, SCOTT H, THORSBY E (1985)
    SUPPRESSOR-CELL ACTIVITY IN CELIAC-DISEASE
    Lancet, 1 (8422), 229
 
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