- B cells and the auto-antibody response of coeliac disease.
- How certain variants of HLA molecules predispose to disease development.
- Characterisation of how T cells recognise gluten protein, the dietary antigen precipitating coeliac disease.
- How transglutaminase (TG) 2 mediated post-translational protein modification increases antigenicity.
Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense
J Immunol, 202 (9), 2558-2569
Distinct phenotype of CD4+ T cells driving celiac disease identified in multiple autoimmune conditions
Nat Med (in press)
Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping
Nat Commun, 10 (1), 628