Publications 2022

Amundsen SF, Stamnaes J, du Pré MF, Sollid LM (2022)
Transglutaminase 2 affinity and enzyme-substrate intermediate stability as determining factors for T-cell responses to gluten peptides in celiac disease
Eur J Immunol, 52 (9), 1474-1481
DOI 10.1002/eji.202249862, PubMed 35715890

Lindstad CB, du Pré MF, Stamnaes J, Sollid LM (2022)
Injection of prototypic celiac anti-transglutaminase 2 antibodies in mice does not cause enteropathy
PLoS One, 17 (4), e0266543
DOI 10.1371/journal.pone.0266543, PubMed 35385534

Publications 2021

Lindstad CB, Dewan AE, Stamnaes J, Sollid LM, du Pré MF (2021)
TG2-gluten complexes as antigens for gluten-specific and transglutaminase-2 specific B cells in celiac disease
PLoS One, 16 (11), e0259082
DOI 10.1371/journal.pone.0259082, PubMed 34731200

Stamnaes J (2021)
Insights from tissue "omics" analysis on intestinal remodeling in celiac disease
Proteomics, 21 (23-24), e2100057
DOI 10.1002/pmic.202100057, PubMed 34633755

Stamnaes J, Stray D, Stensland M, Sarna VK, Nyman TA, Lundin KEA, Sollid LM (2021)
In Well-Treated Celiac Patients Low-Level Mucosal Inflammation Predicts Response to 14-day Gluten Challenge
Adv Sci (Weinh), 8 (4), 2003526
DOI 10.1002/advs.202003526, PubMed 33643806

Publications 2020

du Pré MF, Blazevski J, Dewan AE, Stamnaes J, Kanduri C, Sandve GK, Johannesen MK, Lindstad CB, Hnida K, Fugger L, Melino G, Qiao SW, Sollid LM (2020)
B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2
J Exp Med, 217 (2)
DOI 10.1084/jem.20190860, PubMed 31727780

Iversen R, Amundsen SF, Kleppa L, du Pré MF, Stamnaes J, Sollid LM (2020)
Evidence That Pathogenic Transglutaminase 2 in Celiac Disease Derives From Enterocytes
Gastroenterology, 159 (2), 788-790
DOI 10.1053/j.gastro.2020.04.018, PubMed 32302613

Publications 2019

Iversen R, Roy B, Stamnaes J, Høydahl LS, Hnida K, Neumann RS, Korponay-Szabó IR, Lundin KEA, Sollid LM (2019)
Efficient T cell-B cell collaboration guides autoantibody epitope bias and onset of celiac disease
Proc Natl Acad Sci U S A, 116 (30), 15134-15139
DOI 10.1073/pnas.1901561116, PubMed 31285344

Publications 2018

Tutturen AEV, Dørum S, Clancy T, Reims HM, Christophersen A, Lundin KEA, Sollid LM, de Souza GA, Stamnaes J (2018)
Characterization of the Small Intestinal Lesion in Celiac Disease by Label-Free Quantitative Mass Spectrometry
Am J Pathol, 188 (7), 1563-1579
DOI 10.1016/j.ajpath.2018.03.017, PubMed 29684362

Publications 2016

Cardoso I, Østerlund EC, Stamnaes J, Iversen R, Andersen JT, Jørgensen TJ, Sollid LM (2016)
Dissecting the interaction between transglutaminase 2 and fibronectin
Amino Acids, 49 (3), 489-500
DOI 10.1007/s00726-016-2296-y, PubMed 27394141

Hnida K, Stamnaes J, du Pré MF, Mysling S, Jørgensen TJ, Sollid LM, Iversen R (2016)
Epitope-dependent Functional Effects of Celiac Disease Autoantibodies on Transglutaminase 2
J Biol Chem, 291 (49), 25542-25552
DOI 10.1074/jbc.M116.738161, PubMed 27784785

Stamnaes J, Cardoso I, Iversen R, Sollid LM (2016)
Transglutaminase 2 strongly binds to an extracellular matrix component other than fibronectin via its second C-terminal beta-barrel domain
FEBS J, 283 (21), 3994-4010
DOI 10.1111/febs.13907, PubMed 27685605

Publications 2015

Cardoso I, Stamnaes J, Andersen JT, Melino G, Iversen R, Sollid LM (2015)
Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies
FEBS J, 282 (11), 2063-75
DOI 10.1111/febs.13276, PubMed 25808416

Sollid LM, Iversen R, Steinsbø Ø, Qiao SW, Bergseng E, Dørum S, du Pré MF, Stamnaes J, Christophersen A, Cardoso I, Hnida K, Chen X, Snir O, Lundin KEA (2015)
Small bowel, celiac disease and adaptive immunity
Dig Dis, 33 (2), 115-121
DOI 10.1159/000369512, PubMed 25925911

Stamnaes J, Iversen R, du Pré MF, Chen X, Sollid LM (2015)
Enhanced B-Cell Receptor Recognition of the Autoantigen Transglutaminase 2 by Efficient Catalytic Self-Multimerization
PLoS One, 10 (8), e0134922
DOI 10.1371/journal.pone.0134922, PubMed 26244572

Stamnaes J, Sollid LM (2015)
Celiac disease: Autoimmunity in response to food antigen
Semin Immunol, 27 (5), 343-52
DOI 10.1016/j.smim.2015.11.001, PubMed 26603490

Publications 2014

Dørum S, Bodd M, Fallang LE, Bergseng E, Christophersen A, Johannesen MK, Qiao SW, Stamnaes J, de Souza GA, Sollid LM (2014)
HLA-DQ molecules as affinity matrix for identification of gluten T cell epitopes
J Immunol, 193 (9), 4497-506
DOI 10.4049/jimmunol.1301466, PubMed 25261484

Publications 2013

Iversen R, Di Niro R, Stamnaes J, Lundin KE, Wilson PC, Sollid LM (2013)
Transglutaminase 2-specific autoantibodies in celiac disease target clustered, N-terminal epitopes not displayed on the surface of cells
J Immunol, 190 (12), 5981-91
DOI 10.4049/jimmunol.1300183, PubMed 23690478

Publications 2012

Dafik L, Albertelli M, Stamnaes J, Sollid LM, Khosla C (2012)
Activation and inhibition of transglutaminase 2 in mice
PLoS One, 7 (2), e30642
DOI 10.1371/journal.pone.0030642, PubMed 22319575

Di Niro R, Mesin L, Zheng NY, Stamnaes J, Morrissey M, Lee JH, Huang M, Iversen R, du Pré MF, Qiao SW, Lundin KE, Wilson PC, Sollid LM (2012)
High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions
Nat Med, 18 (3), 441-5
DOI 10.1038/nm.2656, PubMed 22366952

Publications 2011

Jin X, Stamnaes J, Klöck C, DiRaimondo TR, Sollid LM, Khosla C (2011)
Activation of extracellular transglutaminase 2 by thioredoxin
J Biol Chem, 286 (43), 37866-73
DOI 10.1074/jbc.M111.287490, PubMed 21908620

Publications 2010

Stamnaes J, Dorum S, Fleckenstein B, Aeschlimann D, Sollid LM (2010)
Gluten T cell epitope targeting by TG3 and TG6; implications for dermatitis herpetiformis and gluten ataxia
Amino Acids, 39 (5), 1183-91
DOI 10.1007/s00726-010-0554-y, PubMed 20300788

Stamnaes J, Pinkas DM, Fleckenstein B, Khosla C, Sollid LM (2010)
Redox regulation of transglutaminase 2 activity
J Biol Chem, 285 (33), 25402-9
DOI 10.1074/jbc.M109.097162, PubMed 20547769

Publications 2008

Stamnaes J, Fleckenstein B, Lund-Johansen F, Sollid LM (2008)
The monoclonal antibody 6B9 recognizes CD44 and not cell surface transglutaminase 2
Scand J Immunol, 68 (5), 534-42
DOI 10.1111/j.1365-3083.2008.02173.x, PubMed 18803608

Stamnaes J, Fleckenstein B, Sollid LM (2008)
The propensity for deamidation and transamidation of peptides by transglutaminase 2 is dependent on substrate affinity and reaction conditions
Biochim Biophys Acta, 1784 (11), 1804-11
DOI 10.1016/j.bbapap.2008.08.011, PubMed 18793760

Publications 2007

Ráki M, Schjetne KW, Stamnaes J, Molberg Ø, Jahnsen FL, Issekutz TB, Bogen B, Sollid LM (2007)
Surface expression of transglutaminase 2 by dendritic cells and its potential role for uptake and presentation of gluten peptides to T cells
Scand J Immunol, 65 (3), 213-20
DOI 10.1111/j.1365-3083.2006.01881.x, PubMed 17309775