Ludvig M. Sollid

  • Group leader; Dr. med.
  • +47 23 07 38 11
 

Publications 2024

Abadie V, Han AS, Jabri B, Sollid LM (2024)
New Insights on Genes, Gluten, and Immunopathogenesis of Celiac Disease
Gastroenterology, 167 (1), 4-22
DOI 10.1053/j.gastro.2024.03.042, PubMed 38670280

Cubero-Leon E, Madsen CB, Scherf KA, Colgrave ML, Nørgaard JV, Anthoni M, Rizou K, Walker MJ, Sollid LM (2024)
Barley based gluten free beer - A blessing or an uncontrollable risk?
Food Chem Toxicol, 193, 115019 (in press)
DOI 10.1016/j.fct.2024.115019, PubMed 39307344

Das S, Stamnaes J, Høydahl LS, Skagen C, Lundin KEA, Jahnsen J, Sollid LM, Iversen R (2024)
Selective activation of naïve B cells with unique epitope specificity shapes autoantibody formation in celiac disease
J Autoimmun, 146, 103241
DOI 10.1016/j.jaut.2024.103241, PubMed 38754235

Das S, Stamnaes J, Kemppainen E, Hervonen K, Lundin KEA, Parmar N, Jahnsen FL, Jahnsen J, Lindfors K, Salmi T, Iversen R, Sollid LM (2024)
Correction to: Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis
Adv Sci (Weinh), 11 (21), e2400894
DOI 10.1002/advs.202400894, PubMed 38477397

Drosu N, Bjornevik K, Cortese M, Levy M, Sollid LM (2024)
Coeliac disease as a model for understanding multiple sclerosis
Nat Rev Neurol (in press)
DOI 10.1038/s41582-024-01025-y, PubMed 39379493

du Pre MF, Iversen R, Sollid LM (2024)
Coeliac disease: the paradox of diagnosing a food hypersensitivity disorder with autoantibodies
Gut, 73 (5), 844-853
DOI 10.1136/gutjnl-2023-331595, PubMed 38378252

Iversen R, Sollid LM (2024)
Dissecting autoimmune encephalitis through the lens of intrathecal B cells
Proc Natl Acad Sci U S A, 121 (9), e2401337121
DOI 10.1073/pnas.2401337121, PubMed 38354256

Johansen A, Sandve GKF, Ibsen JH, Lundin KEA, Sollid LM, Stamnaes J (2024)
Biopsy Proteome Scoring to Determine Mucosal Remodeling in Celiac Disease
Gastroenterology, 167 (3), 493-504.e10
DOI 10.1053/j.gastro.2024.03.006, PubMed 38467384

Johansen A, Sandve GKF, Maxwell JR, Smithson G, Sollid LM, Stamnaes J (2024)
Biopsy Proteome Score Performs Well as an Effect Measure in a Gluten Challenge Trial of Celiac Disease
Clin Gastroenterol Hepatol (in press)
DOI 10.1016/j.cgh.2024.08.005, PubMed 39209203

Lindeman I, Høydahl LS, Christophersen A, Risnes LF, Jahnsen J, Lundin KEA, Sollid LM, Iversen R (2024)
Generation of circulating autoreactive pre-plasma cells fueled by naive B cells in celiac disease
Cell Rep, 43 (4), 114045
DOI 10.1016/j.celrep.2024.114045, PubMed 38578826

Lukina P, Andersen IL, Eggen PT, Mjønes PG, Rønne E, Bolstad N, Klaasen RA, Warren DJ, Iversen R, Hveem K, Bernklev T, Jelsness-Jørgensen LP, Pedersen L, Jonkers I, Lagergren P, Sollid LM, Lundin K, Ness-Jensen E (2024)
Coeliac disease in the Trøndelag Health Study (HUNT), Norway, a population-based cohort of coeliac disease patients
BMJ Open, 14 (1), e077131
DOI 10.1136/bmjopen-2023-077131, PubMed 38195172

Lukina P, Andersen IL, Klaasen RA, Warren DJ, Bolstad N, Mjønes P, Rønne E, Iversen R, Sollid LM, Lundin KEA, Ness-Jensen E (2024)
The Prevalence and Rate of Undiagnosed Celiac Disease in an Adult General Population, the Trøndelag Health Study, Norway
Clin Gastroenterol Hepatol (in press)
DOI 10.1016/j.cgh.2024.06.027, PubMed 38987013

Meling MT, Kleppa L, Besser HA, Khosla C, du Pré MF, Sollid LM (2024)
Enterocyte-Derived and Catalytically Active Transglutaminase 2 in the Gut Lumen of Mice: Implications for Celiac Disease
Gastroenterology, 167 (5), 1026-1028.e4
DOI 10.1053/j.gastro.2024.05.029, PubMed 38825048

Risnes LF, Reims HM, Doyle RM, Qiao SW, Sollid LM, Lundin KEA, Christophersen A (2024)
Gluten-Free Diet Induces Rapid Changes in Phenotype and Survival Properties of Gluten-Specific T Cells in Celiac Disease
Gastroenterology, 167 (2), 250-263
DOI 10.1053/j.gastro.2024.03.027, PubMed 38552723

Santos AJM, van Unen V, Lin Z, Chirieleison SM, Ha N, Batish A, Chan JE, Cedano J, Zhang ET, Mu Q, Guh-Siesel A, Tomaske M, Colburg D, Varma S, Choi SS, Christophersen A, Baghdasaryan A, Yost KE, Karlsson K, Ha A, Li J, Dai H, Sellers ZM, Chang HY, Dunn JCY et al. (2024)
A human autoimmune organoid model reveals IL-7 function in coeliac disease
Nature, 632 (8024), 401-410
DOI 10.1038/s41586-024-07716-2, PubMed 39048815

Sollid LM (2024)
Tolerance-inducing therapies in coeliac disease - mechanisms, progress and future directions
Nat Rev Gastroenterol Hepatol, 21 (5), 335-347
DOI 10.1038/s41575-024-00895-3, PubMed 38336920

Publications 2023

Amundsen SF, Stamnaes J, Lundin KEA, Sollid LM (2023)
Expression of transglutaminase 2 in human gut epithelial cells: Implications for coeliac disease
PLoS One, 18 (6), e0287662
DOI 10.1371/journal.pone.0287662, PubMed 37368893

Chlubnová M, Christophersen AO, Sandve GKF, Lundin KEA, Jahnsen J, Dahal-Koirala S, Sollid LM (2023)
Identification of gluten T cell epitopes driving celiac disease
Sci Adv, 9 (4), eade5800
DOI 10.1126/sciadv.ade5800, PubMed 36696493

Das S, Stamnaes J, Kemppainen E, Hervonen K, Lundin KEA, Parmar N, Jahnsen FL, Jahnsen J, Lindfors K, Salmi T, Iversen R, Sollid LM (2023)
Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis
Adv Sci (Weinh), 10 (25), e2300401
DOI 10.1002/advs.202300401, PubMed 37424036

Funsten MC, Yurkovetskiy LA, Kuznetsov A, Reiman D, Hansen CHF, Senter KI, Lee J, Ratiu J, Dahal-Koirala S, Antonopoulos DA, Dunny GM, Sollid LM, Serreze D, Khan AA, Chervonsky AV (2023)
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
Cell Host Microbe, 31 (2), 213-227.e9
DOI 10.1016/j.chom.2022.12.009, PubMed 36603588

Heggelund JE, Das S, Stamnaes J, Iversen R, Sollid LM (2023)
Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3
Nat Commun, 14 (1), 6216
DOI 10.1038/s41467-023-42004-z, PubMed 37798283

Okura Y, Ikawa-Teranishi Y, Mizoroki A, Takahashi N, Tsushima T, Irie M, Harfuddin Z, Miura-Okuda M, Ito S, Nakamura G, Takesue H, Ozono Y, Nishihara M, Yamada K, Gan SW, Hayasaka A, Ishii S, Wakabayashi T, Muraoka M, Nagaya N, Hino H, Nemoto T, Kuramochi T, Torizawa T, Shimada H et al. (2023)
Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease
Nat Commun, 14 (1), 8502
DOI 10.1038/s41467-023-44083-4, PubMed 38135691

Polak J, Wagnerberger JH, Torsetnes SB, Lindeman I, Høglund RAA, Vartdal F, Sollid LM, Lossius A (2023)
Single-cell transcriptomics combined with proteomics of intrathecal IgG reveal transcriptional heterogeneity of oligoclonal IgG-secreting cells in multiple sclerosis
Front Cell Neurosci, 17, 1189709
DOI 10.3389/fncel.2023.1189709, PubMed 37362001

Publications 2022

Amundsen SF, Stamnaes J, du Pré MF, Sollid LM (2022)
Transglutaminase 2 affinity and enzyme-substrate intermediate stability as determining factors for T-cell responses to gluten peptides in celiac disease
Eur J Immunol, 52 (9), 1474-1481
DOI 10.1002/eji.202249862, PubMed 35715890

Christophersen A, Dahal-Koirala S, Chlubnová M, Jahnsen J, Lundin KEA, Sollid LM (2022)
Phenotype-Based Isolation of Antigen-Specific CD4+ T Cells in Autoimmunity: A Study of Celiac Disease
Adv Sci (Weinh), 9 (10), e2104766
DOI 10.1002/advs.202104766, PubMed 35119226

Christophersen A, Zühlke S, Lund EG, Snir O, Dahal-Koirala S, Risnes LF, Jahnsen J, Lundin KEA, Sollid LM (2022)
Pathogenic T Cells in Celiac Disease Change Phenotype on Gluten Challenge: Implications for T-Cell-Directed Therapies
Adv Sci (Weinh), 9 (34), e2205912
DOI 10.1002/advs.202205912, PubMed 36482157

Ciacchi L, Farenc C, Dahal-Koirala S, Petersen J, Sollid LM, Reid HH, Rossjohn J (2022)
Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease
J Biol Chem, 298 (3), 101619
DOI 10.1016/j.jbc.2022.101619, PubMed 35065967

Dahal-Koirala S, Balaban G, Neumann RS, Scheffer L, Lundin KEA, Greiff V, Sollid LM, Qiao SW, Sandve GK (2022)
TCRpower: quantifying the detection power of T-cell receptor sequencing with a novel computational pipeline calibrated by spike-in sequences
Brief Bioinform, 23 (2)
DOI 10.1093/bib/bbab566, PubMed 35062022

Frick R, Høydahl LS, Hodnebrug I, Vik ES, Dalhus B, Sollid LM, Gray JJ, Sandlie I, Løset GÅ (2022)
Affinity maturation of TCR-like antibodies using phage display guided by structural modeling
Protein Eng Des Sel, 35
DOI 10.1093/protein/gzac005, PubMed 35871543

Iversen R, Sollid LM (2022)
The Immunobiology and Pathogenesis of Celiac Disease
Annu Rev Pathol, 18, 47-70
DOI 10.1146/annurev-pathmechdis-031521-032634, PubMed 36067801

Klaasen RA, Warren DJ, Iversen R, Bolstad N, Andersen IL, Mjønes P, Rønne E, Lundin KEA, Sollid LM, Ness-Jensen E (2022)
The development and validation of a high-capacity serological assay for celiac disease
Clin Biochem, 107, 13-18
DOI 10.1016/j.clinbiochem.2022.05.010, PubMed 35660483

Li J, Zaslavsky M, Su Y, Guo J, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Mallajosyula VVA, Bracey NA, Dhondalay GKR, Bhamidipati K, Pai J, Kipp LB, Dunn JE, Hauser SL, Oksenberg JR, Satpathy AT, Robinson WH et al. (2022)
KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19
Science, 376 (6590), eabi9591
DOI 10.1126/science.abi9591, PubMed 35258337

Lindeman I, Polak J, Qiao SW, Holmøy T, Høglund RA, Vartdal F, Berg-Hansen P, Sollid LM, Lossius A (2022)
Stereotyped B-cell responses are linked to IgG constant region polymorphisms in multiple sclerosis
Eur J Immunol, 52 (4), 550-565
DOI 10.1002/eji.202149576, PubMed 35094395

Lindstad CB, du Pré MF, Stamnaes J, Sollid LM (2022)
Injection of prototypic celiac anti-transglutaminase 2 antibodies in mice does not cause enteropathy
PLoS One, 17 (4), e0266543
DOI 10.1371/journal.pone.0266543, PubMed 35385534

Risnes LF, Chlubnová M, Magistrelli E, Kemppainen E, Hervonen K, Mansikka E, Lindfors K, Salmi T, Dahal-Koirala S, Sollid LM (2022)
Phenotypic Analysis of Disease-Relevant T Cells in Dermatitis Herpetiformis
J Invest Dermatol, 143 (1), 163-166.e2
DOI 10.1016/j.jid.2022.07.007, PubMed 35961617

Sollid LM (2022)
Epstein-Barr virus as a driver of multiple sclerosis
Sci Immunol, 7 (70), eabo7799
DOI 10.1126/sciimmunol.abo7799, PubMed 35363541

Sollid LM, Iversen R (2022)
Tango of B cells with T cells in the making of secretory antibodies to gut bacteria
Nat Rev Gastroenterol Hepatol, 20 (2), 120-128
DOI 10.1038/s41575-022-00674-y, PubMed 36056203

Zhou C, Østerbye T, Bach E, Dahal-Koirala S, Høydahl LS, Steinsbø Ø, Jahnsen J, Lundin KEA, Buus S, Sollid LM, Iversen R (2022)
Focused B cell response to recurring gluten motif with implications for epitope spreading in celiac disease
Cell Rep, 41 (4), 111541
DOI 10.1016/j.celrep.2022.111541, PubMed 36288703

Publications 2021

Bakker OB, Ramírez-Sánchez AD, Borek ZA, de Klein N, Li Y, Modderman R, Kooy-Winkelaar Y, Johannesen MK, Matarese F, Martens JHA, Kumar V, van Bergen J, Qiao SW, Lundin KEA, Sollid LM, Koning F, Wijmenga C, Withoff S, Jonkers IH (2021)
Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells
Sci Rep, 11 (1), 9252
DOI 10.1038/s41598-021-86612-5, PubMed 33927210

Christophersen A, Zühlke S, Lund EG, Snir O, Dahal-Koirala S, Risnes LF, Jahnsen J, Lundin KEA, Sollid LM (2021)
Pathogenic T Cells in Celiac Disease Change Phenotype on Gluten Challenge: Implications for T-Cell-Directed Therapies
Adv Sci (Weinh), 8 (21), e2102778
DOI 10.1002/advs.202102778, PubMed 34495570

Dahal-Koirala S, Risnes LF, Neumann RS, Christophersen A, Lundin KEA, Sandve GK, Qiao SW, Sollid LM (2021)
Comprehensive Analysis of CDR3 Sequences in Gluten-Specific T-Cell Receptors Reveals a Dominant R-Motif and Several New Minor Motifs
Front Immunol, 12, 639672
DOI 10.3389/fimmu.2021.639672, PubMed 33927715

Dewan AE, Koentgen F, Johannesen MK, du Pre MF, Sollid LM (2021)
Generation of an HLA-DQ2.5 Knock-In Mouse
Immunohorizons, 5 (1), 25-32
DOI 10.4049/immunohorizons.2000107, PubMed 33461981

Eggesbø LM, Risnes LF, Neumann RS, Lundin KEA, Christophersen A, Sollid LM (2021)
Single-cell TCR repertoire analysis reveals highly polyclonal composition of human intraepithelial CD8+ αβ T lymphocytes in untreated celiac disease
Eur J Immunol, 51 (6), 1542-1545
DOI 10.1002/eji.202048974, PubMed 33559929

Frick R, Høydahl LS, Petersen J, du Pré MF, Kumari S, Berntsen G, Dewan AE, Jeliazkov JR, Gunnarsen KS, Frigstad T, Vik ES, Llerena C, Lundin KEA, Yaqub S, Jahnsen J, Gray JJ, Rossjohn J, Sollid LM, Sandlie I, Løset GÅ (2021)
A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation
Sci Immunol, 6 (62)
DOI 10.1126/sciimmunol.abg4925, PubMed 34417258

Li J, Zaslavsky M, Su Y, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Aditya Mallajosyula VV, Dhondalay GKR, Bhamidipati K, Pai J, Kipp LB, Dunn JE, Hauser SL, Oksenberg JR, Satpathy AT, Robinson WH, Steinmetz LM, Khosla C et al. (2021)
Human KIR + CD8 + T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19
bioRxiv
DOI 10.1101/2021.12.23.473930, PubMed 34981055

Lindeman I, Sollid LM (2021)
Single-cell approaches to dissect adaptive immune responses involved in autoimmunity: the case of celiac disease
Mucosal Immunol, 15 (1), 51-63
DOI 10.1038/s41385-021-00452-0, PubMed 34531547

Lindeman I, Zhou C, Eggesbø LM, Miao Z, Polak J, Lundin KEA, Jahnsen J, Qiao SW, Iversen R, Sollid LM (2021)
Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells
J Exp Med, 218 (2)
DOI 10.1084/jem.20200852, PubMed 33095260

Lindstad CB, Dewan AE, Stamnaes J, Sollid LM, du Pré MF (2021)
TG2-gluten complexes as antigens for gluten-specific and transglutaminase-2 specific B cells in celiac disease
PLoS One, 16 (11), e0259082
DOI 10.1371/journal.pone.0259082, PubMed 34731200

Mikocziova I, Greiff V, Sollid LM (2021)
Immunoglobulin germline gene variation and its impact on human disease
Genes Immun, 22 (4), 205-217
DOI 10.1038/s41435-021-00145-5, PubMed 34175903

Mikocziova I, Peres A, Gidoni M, Greiff V, Yaari G, Sollid LM (2021)
Germline polymorphisms and alternative splicing of human immunoglobulin light chain genes
iScience, 24 (10), 103192
DOI 10.1016/j.isci.2021.103192, PubMed 34693229

Pavlović M, Scheffer L, Motwani K, Kanduri C, Kompova R, Vazov N, Waagan K, Bernal FLM, Costa AA, Corrie B, Akbar R, Al Hajj GS, Balaban G, Brusko TM, Chernigovskaya M, Christley S, Cowell LG, Frank R, Grytten I, Gundersen S, Haff IH, Hovig E, Hsieh PH, Klambauer G, Kuijjer ML et al. (2021)
The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires
Nat Mach Intell, 3 (11), 936-944
DOI 10.1038/s42256-021-00413-z, PubMed 37396030

Qiao SW, Dahal-Koirala S, Eggesbø LM, Lundin KEA, Sollid LM (2021)
Frequency of Gluten-Reactive T Cells in Active Celiac Lesions Estimated by Direct Cell Cloning
Front Immunol, 12, 646163
DOI 10.3389/fimmu.2021.646163, PubMed 33796112

Risnes LF, Eggesbø LM, Christophersen A, Sollid LM (2021)
Response to: "Some considerations about γδ and CD8+ T-cell responses in blood after gluten challenge in treated celiac disease"
Mucosal Immunol, 14 (5), 1216-1217
DOI 10.1038/s41385-021-00422-6, PubMed 34108593

Risnes LF, Eggesbø LM, Zühlke S, Dahal-Koirala S, Neumann RS, Lundin KEA, Christophersen A, Sollid LM (2021)
Circulating CD103+ γδ and CD8+ T cells are clonally shared with tissue-resident intraepithelial lymphocytes in celiac disease
Mucosal Immunol, 14 (4), 842-851
DOI 10.1038/s41385-021-00385-8, PubMed 33654213

Shemesh O, Polak P, Lundin KEA, Sollid LM, Yaari G (2021)
Machine Learning Analysis of Naïve B-Cell Receptor Repertoires Stratifies Celiac Disease Patients and Controls
Front Immunol, 12, 627813
DOI 10.3389/fimmu.2021.627813, PubMed 33790900

Slabodkin A, Chernigovskaya M, Mikocziova I, Akbar R, Scheffer L, Pavlović M, Bashour H, Snapkov I, Mehta BB, Weber CR, Gutierrez-Marcos J, Sollid LM, Haff IH, Sandve GK, Robert PA, Greiff V (2021)
Individualized VDJ recombination predisposes the available Ig sequence space
Genome Res, 31 (12), 2209-2224
DOI 10.1101/gr.275373.121, PubMed 34815307

Sollid LM (2021)
Gut tissue-resident memory T cells in coeliac disease
Scand J Immunol, 95 (1), e13120
DOI 10.1111/sji.13120, PubMed 34796982

Sollid LM, Lundin KEA, Leivestad T, Spurkland A, Vartdal F (2021)
Erik Thorsby (1938-2021)
Immunogenetics, 73 (3), 203-205
DOI 10.1007/s00251-021-01218-5, PubMed 33956175

Sollid LM, Lundin KEA, Leivestad T, Spurkland A, Vartdal F (2021)
In memoriam: Erik Thorsby (1938-2021)
Scand. J. Immunol., 94 (1), e13055
DOI 10.1111/sji.13055

Stamnaes J, Stray D, Stensland M, Sarna VK, Nyman TA, Lundin KEA, Sollid LM (2021)
In Well-Treated Celiac Patients Low-Level Mucosal Inflammation Predicts Response to 14-day Gluten Challenge
Adv Sci (Weinh), 8 (4), 2003526
DOI 10.1002/advs.202003526, PubMed 33643806

van der Graaf A, Zorro MM, Claringbould A, Võsa U, Aguirre-Gamboa R, Li C, Mooiweer J, Ricaño-Ponce I, Borek Z, Koning F, Kooy-Winkelaar Y, Sollid LM, Qiao SW, Kumar V, Li Y, Franke L, Withoff S, Wijmenga C, Sanna S, Jonkers I, BIOS Consortium (2021)
Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease
Front Genet, 11, 562434
DOI 10.3389/fgene.2020.562434, PubMed 33569077

Wyrożemski Ł, Sollid LM, Qiao SW (2021)
C-type lectin-like CD161 is not a co-signalling receptor in gluten-reactive CD4 + T cells
Scand J Immunol, 93 (6), e13016
DOI 10.1111/sji.13016, PubMed 33368526

Publications 2020

du Pré MF, Blazevski J, Dewan AE, Stamnaes J, Kanduri C, Sandve GK, Johannesen MK, Lindstad CB, Hnida K, Fugger L, Melino G, Qiao SW, Sollid LM (2020)
B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2
J Exp Med, 217 (2)
DOI 10.1084/jem.20190860, PubMed 31727780

Iversen R, Amundsen SF, Kleppa L, du Pré MF, Stamnaes J, Sollid LM (2020)
Evidence That Pathogenic Transglutaminase 2 in Celiac Disease Derives From Enterocytes
Gastroenterology, 159 (2), 788-790
DOI 10.1053/j.gastro.2020.04.018, PubMed 32302613

Iversen R, Sollid LM (2020)
Autoimmunity provoked by foreign antigens
Science, 368 (6487), 132-133
DOI 10.1126/science.aay3037, PubMed 32273455

Lindstad CB, Qiao SW, Johannesen MK, Fugger L, Sollid LM, du Pré MF (2020)
Characterization of T-cell receptor transgenic mice recognizing immunodominant HLA-DQ2.5-restricted gluten epitopes
Eur J Immunol, 51 (4), 1002-1005
DOI 10.1002/eji.202048859, PubMed 33368209

Mikocziova I, Gidoni M, Lindeman I, Peres A, Snir O, Yaari G, Sollid LM (2020)
Polymorphisms in human immunoglobulin heavy chain variable genes and their upstream regions
Nucleic Acids Res, 48 (10), 5499-5510
DOI 10.1093/nar/gkaa310, PubMed 32365177

Sollid LM, Koning F (2020)
Lack of relationship of AT1001 to zonulin and prehaptoglobin-2: clinical implications
Gut, 70 (11), 2211-2212
DOI 10.1136/gutjnl-2020-323829, PubMed 33443022

Ting YT, Dahal-Koirala S, Kim HSK, Qiao SW, Neumann RS, Lundin KEA, Petersen J, Reid HH, Sollid LM, Rossjohn J (2020)
A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease
Proc Natl Acad Sci U S A, 117 (6), 3063-3073
DOI 10.1073/pnas.1914308117, PubMed 31974305

Publications 2019

Bartolomé-Casado R, Landsverk OJB, Chauhan SK, Richter L, Phung D, Greiff V, Risnes LF, Yao Y, Neumann RS, Yaqub S, Øyen O, Horneland R, Aandahl EM, Paulsen V, Sollid LM, Qiao SW, Baekkevold ES, Jahnsen FL (2019)
Resident memory CD8 T cells persist for years in human small intestine
J Exp Med, 216 (10), 2412-2426
DOI 10.1084/jem.20190414, PubMed 31337737

Christophersen A, Lund EG, Snir O, Solà E, Kanduri C, Dahal-Koirala S, Zühlke S, Molberg Ø, Utz PJ, Rohani-Pichavant M, Simard JF, Dekker CL, Lundin KEA, Sollid LM, Davis MM (2019)
Distinct phenotype of CD4+ T cells driving celiac disease identified in multiple autoimmune conditions
Nat Med, 25 (5), 734-737
DOI 10.1038/s41591-019-0403-9, PubMed 30911136

Christophersen A, Risnes LF, Dahal-Koirala S, Sollid LM (2019)
Therapeutic and Diagnostic Implications of T Cell Scarring in Celiac Disease and Beyond
Trends Mol Med, 25 (10), 836-852
DOI 10.1016/j.molmed.2019.05.009, PubMed 31331739

Dahal-Koirala S, Neumann RS, Jahnsen J, Lundin KEA, Sollid LM (2019)
On the immune response to barley in celiac disease: Biased and public T-cell receptor usage to a barley unique and immunodominant gluten epitope
Eur J Immunol, 50 (2), 256-269
DOI 10.1002/eji.201948253, PubMed 31628754

Eggesbø LM, Risnes LF, Neumann RS, Lundin KEA, Christophersen A, Sollid LM (2019)
Single-cell TCR sequencing of gut intraepithelial γδ T cells reveals a vast and diverse repertoire in celiac disease
Mucosal Immunol, 13 (2), 313-321
DOI 10.1038/s41385-019-0222-9, PubMed 31728027

Frick R, Gunnarsen KS, Dahal-Koirala S, Risnes LF, Sollid LM, Sandlie I, Høydahl LS, Løset GÅ (2019)
A TRAV26-1-encoded recognition motif focuses the biased T cell response in celiac disease
Eur J Immunol, 50 (1), 142-145
DOI 10.1002/eji.201948235, PubMed 31580480

Gidoni M, Snir O, Peres A, Polak P, Lindeman I, Mikocziova I, Sarna VK, Lundin KEA, Clouser C, Vigneault F, Collins AM, Sollid LM, Yaari G (2019)
Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping
Nat Commun, 10 (1), 628
DOI 10.1038/s41467-019-08489-3, PubMed 30733445

Goel G, Tye-Din JA, Qiao SW, Russell AK, Mayassi T, Ciszewski C, Sarna VK, Wang S, Goldstein KE, Dzuris JL, Williams LJ, Xavier RJ, Lundin KEA, Jabri B, Sollid LM, Anderson RP (2019)
Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease
Sci Adv, 5 (8), eaaw7756
DOI 10.1126/sciadv.aaw7756, PubMed 31457091

Hung SC, Hou T, Jiang W, Wang N, Qiao SW, Chow IT, Liu X, van der Burg SH, Koelle DM, Kwok WW, Sollid LM, Mellins ED (2019)
Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense
J Immunol, 202 (9), 2558-2569
DOI 10.4049/jimmunol.1801454, PubMed 30926644

Iversen R, Roy B, Stamnaes J, Høydahl LS, Hnida K, Neumann RS, Korponay-Szabó IR, Lundin KEA, Sollid LM (2019)
Efficient T cell-B cell collaboration guides autoantibody epitope bias and onset of celiac disease
Proc Natl Acad Sci U S A, 116 (30), 15134-15139
DOI 10.1073/pnas.1901561116, PubMed 31285344

Qiao SW, Sollid LM (2019)
Two novel HLA-DQ2.5-restricted gluten T cell epitopes in the DQ2.5-glia-γ4 epitope family
Immunogenetics, 71 (10), 665-667
DOI 10.1007/s00251-019-01138-5, PubMed 31673720

Snir O, Kanduri C, Lundin KEA, Sandve GK, Sollid LM (2019)
Transcriptional profiling of human intestinal plasma cells reveals effector functions beyond antibody production
United European Gastroenterol J, 7 (10), 1399-1407
DOI 10.1177/2050640619862461, PubMed 31839965

Sollid LM, Tye-Din JA, Qiao SW, Anderson RP, Gianfrani C, Koning F (2019)
Update 2020: nomenclature and listing of celiac disease-relevant gluten epitopes recognized by CD4+ T cells
Immunogenetics, 72 (1-2), 85-88
DOI 10.1007/s00251-019-01141-w, PubMed 31735991

Tye-Din JA, Skodje GI, Sarna VK, Dzuris JL, Russell AK, Goel G, Wang S, Goldstein KE, Williams LJ, Sollid LM, Lundin KE, Anderson RP (2019)
Cytokine release after gluten ingestion differentiates coeliac disease from self-reported gluten sensitivity
United European Gastroenterol J, 8 (1), 108-118
DOI 10.1177/2050640619874173, PubMed 32213060

Zühlke S, Risnes LF, Dahal-Koirala S, Christophersen A, Sollid LM, Lundin KE (2019)
CD38 expression on gluten-specific T cells is a robust marker of gluten re-exposure in coeliac disease
United European Gastroenterol J, 7 (10), 1337-1344
DOI 10.1177/2050640619874183, PubMed 31839959

Publications 2018

Dahal-Koirala S, Ciacchi L, Petersen J, Risnes LF, Neumann RS, Christophersen A, Lundin KEA, Reid HH, Qiao SW, Rossjohn J, Sollid LM (2018)
Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes
J Biol Chem, 294 (3), 941-952
DOI 10.1074/jbc.RA118.005736, PubMed 30455354

Gunnarsen KS, Høydahl LS, Neumann RS, Bjerregaard-Andersen K, Nilssen NR, Sollid LM, Sandlie I, Løset GÅ (2018)
Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system
PLoS One, 13 (4), e0195868
DOI 10.1371/journal.pone.0195868, PubMed 29649333

Høydahl LS, Richter L, Frick R, Snir O, Gunnarsen KS, Landsverk OJB, Iversen R, Jeliazkov JR, Gray JJ, Bergseng E, Foss S, Qiao SW, Lundin KEA, Jahnsen J, Jahnsen FL, Sandlie I, Sollid LM, Løset GÅ (2018)
Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease
Gastroenterology, 156 (5), 1428-1439.e10
DOI 10.1053/j.gastro.2018.12.013, PubMed 30593798

Lindeman I, Emerton G, Mamanova L, Snir O, Polanski K, Qiao SW, Sollid LM, Teichmann SA, Stubbington MJT (2018)
BraCeR: B-cell-receptor reconstruction and clonality inference from single-cell RNA-seq
Nat Methods, 15 (8), 563-565
DOI 10.1038/s41592-018-0082-3, PubMed 30065371

Risnes LF, Christophersen A, Dahal-Koirala S, Neumann RS, Sandve GK, Sarna VK, Lundin KE, Qiao SW, Sollid LM (2018)
Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease
J Clin Invest, 128 (6), 2642-2650
DOI 10.1172/JCI98819, PubMed 29757191

Shao W, Pedrioli PGA, Wolski W, Scurtescu C, Schmid E, Vizcaíno JA, Courcelles M, Schuster H, Kowalewski D, Marino F, Arlehamn CSL, Vaughan K, Peters B, Sette A, Ottenhoff THM, Meijgaarden KE, Nieuwenhuizen N, Kaufmann SHE, Schlapbach R, Castle JC, Nesvizhskii AI, Nielsen M, Deutsch EW, Campbell DS, Moritz RL et al. (2018)
The SysteMHC Atlas project
Nucleic Acids Res, 46 (D1), D1237-D1247
DOI 10.1093/nar/gkx664, PubMed 28985418

Tutturen AEV, Dørum S, Clancy T, Reims HM, Christophersen A, Lundin KEA, Sollid LM, de Souza GA, Stamnaes J (2018)
Characterization of the Small Intestinal Lesion in Celiac Disease by Label-Free Quantitative Mass Spectrometry
Am J Pathol, 188 (7), 1563-1579
DOI 10.1016/j.ajpath.2018.03.017, PubMed 29684362

Publications 2017

Goel G, King T, Daveson AJ, Andrews JM, Krishnarajah J, Krause R, Brown GJE, Fogel R, Barish CF, Epstein R, Kinney TP, Miner PB, Tye-Din JA, Girardin A, Taavela J, Popp A, Sidney J, Mäki M, Goldstein KE, Griffin PH, Wang S, Dzuris JL, Williams LJ, Sette A, Xavier RJ et al. (2017)
Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies
Lancet Gastroenterol Hepatol, 2 (7), 479-493
DOI 10.1016/S2468-1253(17)30110-3, PubMed 28506538

Gunnarsen KS, Høydahl LS, Risnes LF, Dahal-Koirala S, Neumann RS, Bergseng E, Frigstad T, Frick R, du Pré MF, Dalhus B, Lundin KE, Qiao SW, Sollid LM, Sandlie I, Løset GÅ (2017)
A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions
JCI Insight, 2 (17)
DOI 10.1172/jci.insight.95193, PubMed 28878121

Iversen R, Snir O, Stensland M, Kroll JE, Steinsbø Ø, Korponay-Szabó IR, Lundin KEA, de Souza GA, Sollid LM (2017)
Strong Clonal Relatedness between Serum and Gut IgA despite Different Plasma Cell Origins
Cell Rep, 20 (10), 2357-2367
DOI 10.1016/j.celrep.2017.08.036, PubMed 28877470

Jabri B, Sollid LM (2017)
T Cells in Celiac Disease
J Immunol, 198 (8), 3005-3014
DOI 10.4049/jimmunol.1601693, PubMed 28373482

Landsverk OJ, Snir O, Casado RB, Richter L, Mold JE, Réu P, Horneland R, Paulsen V, Yaqub S, Aandahl EM, Øyen OM, Thorarensen HS, Salehpour M, Possnert G, Frisén J, Sollid LM, Baekkevold ES, Jahnsen FL (2017)
Antibody-secreting plasma cells persist for decades in human intestine
J Exp Med, 214 (2), 309-317
DOI 10.1084/jem.20161590, PubMed 28104812

Nguyen TB, Jayaraman P, Bergseng E, Madhusudhan MS, Kim CY, Sollid LM (2017)
Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides
J Biol Chem, 292 (22), 9218-9228
DOI 10.1074/jbc.M117.785139, PubMed 28364043

Ráki M, Dahal-Koirala S, Yu H, Korponay-Szabó IR, Gyimesi J, Castillejo G, Jahnsen J, Qiao SW, Sollid LM (2017)
Similar Responses of Intestinal T Cells From Untreated Children and Adults With Celiac Disease to Deamidated Gluten Epitopes
Gastroenterology, 153 (3), 787-798.e4
DOI 10.1053/j.gastro.2017.05.016, PubMed 28535873

Roy B, Neumann RS, Snir O, Iversen R, Sandve GK, Lundin KEA, Sollid LM (2017)
High-Throughput Single-Cell Analysis of B Cell Receptor Usage among Autoantigen-Specific Plasma Cells in Celiac Disease
J Immunol, 199 (2), 782-791
DOI 10.4049/jimmunol.1700169, PubMed 28600290

Sarna VK, Lundin KEA, Mørkrid L, Qiao SW, Sollid LM, Christophersen A (2017)
HLA-DQ-Gluten Tetramer Blood Test Accurately Identifies Patients With and Without Celiac Disease in Absence of Gluten Consumption
Gastroenterology, 154 (4), 886-896.e6
DOI 10.1053/j.gastro.2017.11.006, PubMed 29146521

Sarna VK, Skodje GI, Reims HM, Risnes LF, Dahal-Koirala S, Sollid LM, Lundin KEA (2017)
HLA-DQ:gluten tetramer test in blood gives better detection of coeliac patients than biopsy after 14-day gluten challenge
Gut, 67 (9), 1606-1613
DOI 10.1136/gutjnl-2017-314461, PubMed 28779027

Snir O, Chen X, Gidoni M, du Pré MF, Zhao Y, Steinsbø Ø, Lundin KE, Yaari G, Sollid LM (2017)
Stereotyped antibody responses target posttranslationally modified gluten in celiac disease
JCI Insight, 2 (17)
DOI 10.1172/jci.insight.93961, PubMed 28878138

Sollid LM (2017)
The roles of MHC class II genes and post-translational modification in celiac disease
Immunogenetics, 69 (8-9), 605-616
DOI 10.1007/s00251-017-0985-7, PubMed 28695286

Sollid LM, Lycke N (2017)
Per Brandtzaeg: patron of mucosal immunology
Mucosal Immunol, 10 (1), 1-4
DOI 10.1038/mi.2016.111, PubMed 28138161

Viken MK, Flåm ST, Skrivarhaug T, Amundsen SS, Sollid LM, Drivvoll AK, Joner G, Dahl-Jørgensen K, Lie BA (2017)
HLA class II alleles in Norwegian patients with coexisting type 1 diabetes and celiac disease
HLA, 89 (5), 278-284
DOI 10.1111/tan.12986, PubMed 28247576

Publications 2016

Cardoso I, Østerlund EC, Stamnaes J, Iversen R, Andersen JT, Jørgensen TJ, Sollid LM (2016)
Dissecting the interaction between transglutaminase 2 and fibronectin
Amino Acids, 49 (3), 489-500
DOI 10.1007/s00726-016-2296-y, PubMed 27394141

Christophersen A, Risnes LF, Bergseng E, Lundin KE, Sollid LM, Qiao SW (2016)
Healthy HLA-DQ2.5+ Subjects Lack Regulatory and Memory T Cells Specific for Immunodominant Gluten Epitopes of Celiac Disease
J Immunol, 196 (6), 2819-26
DOI 10.4049/jimmunol.1501152, PubMed 26895834

Dahal-Koirala S, Risnes LF, Christophersen A, Sarna VK, Lundin KE, Sollid LM, Qiao SW (2016)
TCR sequencing of single cells reactive to DQ2.5-glia-α2 and DQ2.5-glia-ω2 reveals clonal expansion and epitope-specific V-gene usage
Mucosal Immunol, 9 (3), 587-96
DOI 10.1038/mi.2015.147, PubMed 26838051

Dørum S, Steinsbø Ø, Bergseng E, Arntzen MØ, de Souza GA, Sollid LM (2016)
Gluten-specific antibodies of celiac disease gut plasma cells recognize long proteolytic fragments that typically harbor T-cell epitopes
Sci Rep, 6, 25565
DOI 10.1038/srep25565, PubMed 27146306

Hnida K, Stamnaes J, du Pré MF, Mysling S, Jørgensen TJ, Sollid LM, Iversen R (2016)
Epitope-dependent Functional Effects of Celiac Disease Autoantibodies on Transglutaminase 2
J Biol Chem, 291 (49), 25542-25552
DOI 10.1074/jbc.M116.738161, PubMed 27784785

Høydahl LS, Nilssen NR, Gunnarsen KS, Pré MF, Iversen R, Roos N, Chen X, Michaelsen TE, Sollid LM, Sandlie I, Løset GÅ (2016)
Multivalent pIX phage display selects for distinct and improved antibody properties
Sci Rep, 6, 39066
DOI 10.1038/srep39066, PubMed 27966617

Spencer J, Sollid LM (2016)
The human intestinal B-cell response
Mucosal Immunol, 9 (5), 1113-24
DOI 10.1038/mi.2016.59, PubMed 27461177

Stamnaes J, Cardoso I, Iversen R, Sollid LM (2016)
Transglutaminase 2 strongly binds to an extracellular matrix component other than fibronectin via its second C-terminal beta-barrel domain
FEBS J, 283 (21), 3994-4010
DOI 10.1111/febs.13907, PubMed 27685605

Publications 2015

Cardoso I, Stamnaes J, Andersen JT, Melino G, Iversen R, Sollid LM (2015)
Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies
FEBS J, 282 (11), 2063-75
DOI 10.1111/febs.13276, PubMed 25808416

Chen X, Hnida K, Graewert MA, Andersen JT, Iversen R, Tuukkanen A, Svergun D, Sollid LM (2015)
Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease
J Biol Chem, 290 (35), 21365-75
DOI 10.1074/jbc.M115.669895, PubMed 26160175

Di Niro R, Snir O, Kaukinen K, Yaari G, Lundin KE, Gupta NT, Kleinstein SH, Cols M, Cerutti A, Mäki M, Shlomchik MJ, Sollid LM (2015)
Responsive population dynamics and wide seeding into the duodenal lamina propria of transglutaminase-2-specific plasma cells in celiac disease
Mucosal Immunol, 9 (1), 254-64
DOI 10.1038/mi.2015.57, PubMed 26153762

du Pré MF, Sollid LM (2015)
T-cell and B-cell immunity in celiac disease
Best Pract Res Clin Gastroenterol, 29 (3), 413-23
DOI 10.1016/j.bpg.2015.04.001, PubMed 26060106

Iversen R, Fleur du Pré M, Di Niro R, Sollid LM (2015)
Igs as Substrates for Transglutaminase 2: Implications for Autoantibody Production in Celiac Disease
J Immunol, 195 (11), 5159-68
DOI 10.4049/jimmunol.1501363, PubMed 26503953

Lundin KE, Qiao SW, Snir O, Sollid LM (2015)
Coeliac disease - from genetic and immunological studies to clinical applications
Scand J Gastroenterol, 50 (6), 708-17
DOI 10.3109/00365521.2015.1030766, PubMed 25846940

Riaz T, Sollid LM, Olsen I, de Souza GA (2015)
Quantitative Proteomics of Gut-Derived Th1 and Th1/Th17 Clones Reveal the Presence of CD28+ NKG2D- Th1 Cytotoxic CD4+ T cells
Mol Cell Proteomics, 15 (3), 1007-16
DOI 10.1074/mcp.M115.050138, PubMed 26637539

Snir O, Mesin L, Gidoni M, Lundin KE, Yaari G, Sollid LM (2015)
Analysis of celiac disease autoreactive gut plasma cells and their corresponding memory compartment in peripheral blood using high-throughput sequencing
J Immunol, 194 (12), 5703-12
DOI 10.4049/jimmunol.1402611, PubMed 25972486

Sollid LM, Iversen R, Steinsbø Ø, Qiao SW, Bergseng E, Dørum S, du Pré MF, Stamnaes J, Christophersen A, Cardoso I, Hnida K, Chen X, Snir O, Lundin KEA (2015)
Small bowel, celiac disease and adaptive immunity
Dig Dis, 33 (2), 115-121
DOI 10.1159/000369512, PubMed 25925911

Stamnaes J, Iversen R, du Pré MF, Chen X, Sollid LM (2015)
Enhanced B-Cell Receptor Recognition of the Autoantigen Transglutaminase 2 by Efficient Catalytic Self-Multimerization
PLoS One, 10 (8), e0134922
DOI 10.1371/journal.pone.0134922, PubMed 26244572

Stamnaes J, Sollid LM (2015)
Celiac disease: Autoimmunity in response to food antigen
Semin Immunol, 27 (5), 343-52
DOI 10.1016/j.smim.2015.11.001, PubMed 26603490

Steinsbø Ø, Dørum S, Lundin KE, Sollid LM (2015)
Serologic assay for diagnosis of celiac disease based on a patient-derived monoclonal antigliadin antibody
Gastroenterology, 149 (6), 1530-1540.e3
DOI 10.1053/j.gastro.2015.07.008, PubMed 26208894

Publications 2014

Amundsen SS, Viken MK, Sollid LM, Lie BA (2014)
Coeliac disease-associated polymorphisms influence thymic gene expression
Genes Immun, 15 (6), 355-60
DOI 10.1038/gene.2014.26, PubMed 24871462

Bergseng E, Dørum S, Arntzen MØ, Nielsen M, Nygård S, Buus S, de Souza GA, Sollid LM (2014)
Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires
Immunogenetics, 67 (2), 73-84
DOI 10.1007/s00251-014-0819-9, PubMed 25502872

Christophersen A, Ráki M, Bergseng E, Lundin KE, Jahnsen J, Sollid LM, Qiao SW (2014)
Tetramer-visualized gluten-specific CD4+ T cells in blood as a potential diagnostic marker for coeliac disease without oral gluten challenge
United European Gastroenterol J, 2 (4), 268-78
DOI 10.1177/2050640614540154, PubMed 25083284

Dørum S, Bodd M, Fallang LE, Bergseng E, Christophersen A, Johannesen MK, Qiao SW, Stamnaes J, de Souza GA, Sollid LM (2014)
HLA-DQ molecules as affinity matrix for identification of gluten T cell epitopes
J Immunol, 193 (9), 4497-506
DOI 10.4049/jimmunol.1301466, PubMed 25261484

Iversen R, Mysling S, Hnida K, Jørgensen TJ, Sollid LM (2014)
Activity-regulating structural changes and autoantibody epitopes in transglutaminase 2 assessed by hydrogen/deuterium exchange
Proc Natl Acad Sci U S A, 111 (48), 17146-51
DOI 10.1073/pnas.1407457111, PubMed 25404341

Jabri B, Chen X, Sollid LM (2014)
How T cells taste gluten in celiac disease
Nat Struct Mol Biol, 21 (5), 429-31
DOI 10.1038/nsmb.2826, PubMed 24777059

Lundin KE, Sollid LM (2014)
Advances in coeliac disease
Curr Opin Gastroenterol, 30 (2), 154-62
DOI 10.1097/MOG.0000000000000041, PubMed 24457347

Sollid LM, Pos W, Wucherpfennig KW (2014)
Molecular mechanisms for contribution of MHC molecules to autoimmune diseases
Curr Opin Immunol, 31, 24-30
DOI 10.1016/j.coi.2014.08.005, PubMed 25216261

Steinsbø Ø, Henry Dunand CJ, Huang M, Mesin L, Salgado-Ferrer M, Lundin KE, Jahnsen J, Wilson PC, Sollid LM (2014)
Restricted VH/VL usage and limited mutations in gluten-specific IgA of coeliac disease lesion plasma cells
Nat Commun, 5, 4041
DOI 10.1038/ncomms5041, PubMed 24909383

Toft-Hansen H, Rasmussen KS, Staal A, Roggen EL, Sollid LM, Lillevang ST, Barington T, Husby S (2014)
Treatment of both native and deamidated gluten peptides with an endo-peptidase from Aspergillus niger prevents stimulation of gut-derived gluten-reactive T cells from either children or adults with celiac disease
Clin Immunol, 153 (2), 323-31
DOI 10.1016/j.clim.2014.05.009, PubMed 24905137

Publications 2013

Bodd M, Ráki M, Bergseng E, Jahnsen J, Lundin KE, Sollid LM (2013)
Direct cloning and tetramer staining to measure the frequency of intestinal gluten-reactive T cells in celiac disease
Eur J Immunol, 43 (10), 2605-12
DOI 10.1002/eji.201343382, PubMed 23775608

Brottveit M, Beitnes AC, Tollefsen S, Bratlie JE, Jahnsen FL, Johansen FE, Sollid LM, Lundin KE (2013)
Mucosal cytokine response after short-term gluten challenge in celiac disease and non-celiac gluten sensitivity
Am J Gastroenterol, 108 (5), 842-50
DOI 10.1038/ajg.2013.91, PubMed 23588237

Iversen R, Di Niro R, Stamnaes J, Lundin KE, Wilson PC, Sollid LM (2013)
Transglutaminase 2-specific autoantibodies in celiac disease target clustered, N-terminal epitopes not displayed on the surface of cells
J Immunol, 190 (12), 5981-91
DOI 10.4049/jimmunol.1300183, PubMed 23690478

Olsen I, Lundin KE, Sollid LM (2013)
Increased frequency of intestinal CD4+ T cells reactive with mycobacteria in patients with Crohn's disease
Scand J Gastroenterol, 48 (11), 1278-85
DOI 10.3109/00365521.2013.837952, PubMed 24131402

Olsen I, Sollid LM (2013)
Pitfalls in determining the cytokine profile of human T cells
J Immunol Methods, 390 (1-2), 106-12
DOI 10.1016/j.jim.2013.01.015, PubMed 23416458

Qiao SW, Christophersen A, Lundin KE, Sollid LM (2013)
Biased usage and preferred pairing of α- and β-chains of TCRs specific for an immunodominant gluten epitope in coeliac disease
Int Immunol, 26 (1), 13-9
DOI 10.1093/intimm/dxt037, PubMed 24038601

Ráki M, Beitnes AC, Lundin KE, Jahnsen J, Jahnsen FL, Sollid LM (2013)
Plasmacytoid dendritic cells are scarcely represented in the human gut mucosa and are not recruited to the celiac lesion
Mucosal Immunol, 6 (5), 985-92
DOI 10.1038/mi.2012.136, PubMed 23340820

Sollid LM, Jabri B (2013)
Triggers and drivers of autoimmunity: lessons from coeliac disease
Nat Rev Immunol, 13 (4), 294-302
DOI 10.1038/nri3407, PubMed 23493116

Sollid LM, Villadangos JA (2013)
Antigen processing
Curr Opin Immunol, 25 (1), 71-3
DOI 10.1016/j.coi.2012.12.002, PubMed 23287556

Publications 2012

Beitnes AC, Ráki M, Brottveit M, Lundin KE, Jahnsen FL, Sollid LM (2012)
Rapid accumulation of CD14+CD11c+ dendritic cells in gut mucosa of celiac disease after in vivo gluten challenge
PLoS One, 7 (3), e33556
DOI 10.1371/journal.pone.0033556, PubMed 22438948

Bodd M, Tollefsen S, Bergseng E, Lundin KE, Sollid LM (2012)
Evidence that HLA-DQ9 confers risk to celiac disease by presence of DQ9-restricted gluten-specific T cells
Hum Immunol, 73 (4), 376-81
DOI 10.1016/j.humimm.2012.01.016, PubMed 22342873

Dafik L, Albertelli M, Stamnaes J, Sollid LM, Khosla C (2012)
Activation and inhibition of transglutaminase 2 in mice
PLoS One, 7 (2), e30642
DOI 10.1371/journal.pone.0030642, PubMed 22319575

Di Niro R, Mesin L, Zheng NY, Stamnaes J, Morrissey M, Lee JH, Huang M, Iversen R, du Pré MF, Qiao SW, Lundin KE, Wilson PC, Sollid LM (2012)
High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions
Nat Med, 18 (3), 441-5
DOI 10.1038/nm.2656, PubMed 22366952

Mesin L, Sollid LM, Di Niro R (2012)
The intestinal B-cell response in celiac disease
Front Immunol, 3, 313
DOI 10.3389/fimmu.2012.00313, PubMed 23060888

Qiao SW, Iversen R, Ráki M, Sollid LM (2012)
The adaptive immune response in celiac disease
Semin Immunopathol, 34 (4), 523-40
DOI 10.1007/s00281-012-0314-z, PubMed 22535446

Sollid LM, Qiao SW, Anderson RP, Gianfrani C, Koning F (2012)
Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules
Immunogenetics, 64 (6), 455-60
DOI 10.1007/s00251-012-0599-z, PubMed 22322673

Tollefsen S, Hotta K, Chen X, Simonsen B, Swaminathan K, Mathews II, Sollid LM, Kim CY (2012)
Structural and functional studies of trans-encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) protein molecule
J Biol Chem, 287 (17), 13611-9
DOI 10.1074/jbc.M111.320374, PubMed 22362761

Publications 2011

Abadie V, Sollid LM, Barreiro LB, Jabri B (2011)
Integration of genetic and immunological insights into a model of celiac disease pathogenesis
Annu Rev Immunol, 29, 493-525
DOI 10.1146/annurev-immunol-040210-092915, PubMed 21219178

Beitnes AC, Ráki M, Lundin KE, Jahnsen J, Sollid LM, Jahnsen FL (2011)
Density of CD163+ CD11c+ dendritic cells increases and CD103+ dendritic cells decreases in the coeliac lesion
Scand J Immunol, 74 (2), 186-94
DOI 10.1111/j.1365-3083.2011.02549.x, PubMed 21392045

Bodd M, Kim CY, Lundin KE, Sollid LM (2011)
T-cell response to gluten in patients with HLA-DQ2.2 reveals requirement of peptide-MHC stability in celiac disease
Gastroenterology, 142 (3), 552-61
DOI 10.1053/j.gastro.2011.11.021, PubMed 22108197

Brottveit M, Ráki M, Bergseng E, Fallang LE, Simonsen B, Løvik A, Larsen S, Løberg EM, Jahnsen FL, Sollid LM, Lundin KE (2011)
Assessing possible celiac disease by an HLA-DQ2-gliadin Tetramer Test
Am J Gastroenterol, 106 (7), 1318-24
DOI 10.1038/ajg.2011.23, PubMed 21364548

Du Pré MF, Kozijn AE, van Berkel LA, ter Borg MN, Lindenbergh-Kortleve D, Jensen LT, Kooy-Winkelaar Y, Koning F, Boon L, Nieuwenhuis EE, Sollid LM, Fugger L, Samsom JN (2011)
Tolerance to ingested deamidated gliadin in mice is maintained by splenic, type 1 regulatory T cells
Gastroenterology, 141 (2), 610-20, 620.e1-2
DOI 10.1053/j.gastro.2011.04.048, PubMed 21683079

du Pré MF, van Berkel LA, Ráki M, van Leeuwen MA, de Ruiter LF, Broere F, Ter Borg MN, Lund FE, Escher JC, Lundin KE, Sollid LM, Kraal G, Nieuwenhuis EE, Samsom JN (2011)
CD62L(neg)CD38⁺ expression on circulating CD4⁺ T cells identifies mucosally differentiated cells in protein fed mice and in human celiac disease patients and controls
Am J Gastroenterol, 106 (6), 1147-59
DOI 10.1038/ajg.2011.24, PubMed 21386831

Halvorsen EH, Strønen E, Hammer HB, Goll GL, Sollid LM, Molberg O (2011)
Interleukin-15 induces interleukin-17 production by synovial T cell lines from patients with rheumatoid arthritis
Scand J Immunol, 73 (3), 243-9
DOI 10.1111/j.1365-3083.2010.02498.x, PubMed 21204897

Jin X, Stamnaes J, Klöck C, DiRaimondo TR, Sollid LM, Khosla C (2011)
Activation of extracellular transglutaminase 2 by thioredoxin
J Biol Chem, 286 (43), 37866-73
DOI 10.1074/jbc.M111.287490, PubMed 21908620

Jüse U, Arntzen M, Højrup P, Fleckenstein B, Sollid LM (2011)
Assessing high affinity binding to HLA-DQ2.5 by a novel peptide library based approach
Bioorg Med Chem, 19 (7), 2470-7
DOI 10.1016/j.bmc.2011.01.057, PubMed 21382721

Mesin L, Di Niro R, Thompson KM, Lundin KE, Sollid LM (2011)
Long-lived plasma cells from human small intestine biopsies secrete immunoglobulins for many weeks in vitro
J Immunol, 187 (6), 2867-74
DOI 10.4049/jimmunol.1003181, PubMed 21841131

Pollmann S, Stensland M, Halvorsen EH, Sollid LM, Kvien TK, Fleckenstein B, Molberg O (2011)
Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate
Rheumatol Int, 32 (5), 1271-6
DOI 10.1007/s00296-010-1765-y, PubMed 21267570

Qiao SW, Ráki M, Gunnarsen KS, Løset GÅ, Lundin KE, Sandlie I, Sollid LM (2011)
Posttranslational modification of gluten shapes TCR usage in celiac disease
J Immunol, 187 (6), 3064-71
DOI 10.4049/jimmunol.1101526, PubMed 21849672

Sollid LM, Jabri B (2011)
Celiac disease and transglutaminase 2: a model for posttranslational modification of antigens and HLA association in the pathogenesis of autoimmune disorders
Curr Opin Immunol, 23 (6), 732-8
DOI 10.1016/j.coi.2011.08.006, PubMed 21917438

Sollid LM, Khosla C (2011)
Novel therapies for coeliac disease
J Intern Med, 269 (6), 604-13
DOI 10.1111/j.1365-2796.2011.02376.x, PubMed 21401739

Publications 2010

Bodd M, Ráki M, Tollefsen S, Fallang LE, Bergseng E, Lundin KE, Sollid LM (2010)
HLA-DQ2-restricted gluten-reactive T cells produce IL-21 but not IL-17 or IL-22
Mucosal Immunol, 3 (6), 594-601
DOI 10.1038/mi.2010.36, PubMed 20571486

Di Niro R, Mesin L, Raki M, Zheng NY, Lund-Johansen F, Lundin KE, Charpilienne A, Poncet D, Wilson PC, Sollid LM (2010)
Rapid generation of rotavirus-specific human monoclonal antibodies from small-intestinal mucosa
J Immunol, 185 (9), 5377-83
DOI 10.4049/jimmunol.1001587, PubMed 20935207

Dørum S, Arntzen MØ, Qiao SW, Holm A, Koehler CJ, Thiede B, Sollid LM, Fleckenstein B (2010)
The preferred substrates for transglutaminase 2 in a complex wheat gluten digest are Peptide fragments harboring celiac disease T-cell epitopes
PLoS One, 5 (11), e14056
DOI 10.1371/journal.pone.0014056, PubMed 21124911

Gil-Humanes J, Pistón F, Tollefsen S, Sollid LM, Barro F (2010)
Effective shutdown in the expression of celiac disease-related wheat gliadin T-cell epitopes by RNA interference
Proc Natl Acad Sci U S A, 107 (39), 17023-8
DOI 10.1073/pnas.1007773107, PubMed 20829492

Jüse U, van de Wal Y, Koning F, Sollid LM, Fleckenstein B (2010)
Design of new high-affinity peptide ligands for human leukocyte antigen-DQ2 using a positional scanning peptide library
Hum Immunol, 71 (5), 475-81
DOI 10.1016/j.humimm.2010.01.021, PubMed 20105447

Stamnaes J, Dorum S, Fleckenstein B, Aeschlimann D, Sollid LM (2010)
Gluten T cell epitope targeting by TG3 and TG6; implications for dermatitis herpetiformis and gluten ataxia
Amino Acids, 39 (5), 1183-91
DOI 10.1007/s00726-010-0554-y, PubMed 20300788

Stamnaes J, Pinkas DM, Fleckenstein B, Khosla C, Sollid LM (2010)
Redox regulation of transglutaminase 2 activity
J Biol Chem, 285 (33), 25402-9
DOI 10.1074/jbc.M109.097162, PubMed 20547769

Publications 2009

Amundsen SS, Rundberg J, Adamovic S, Gudjónsdóttir AH, Ascher H, Ek J, Nilsson S, Lie BA, Naluai AT, Sollid LM (2009)
Four novel coeliac disease regions replicated in an association study of a Swedish-Norwegian family cohort
Genes Immun, 11 (1), 79-86
DOI 10.1038/gene.2009.67, PubMed 19693089

Bethune MT, Crespo-Bosque M, Bergseng E, Mazumdar K, Doyle L, Sestak K, Sollid LM, Khosla C (2009)
Noninflammatory gluten peptide analogs as biomarkers for celiac sprue
Chem Biol, 16 (8), 868-81
DOI 10.1016/j.chembiol.2009.07.009, PubMed 19716477

Dørum S, Qiao SW, Sollid LM, Fleckenstein B (2009)
A quantitative analysis of transglutaminase 2-mediated deamidation of gluten peptides: implications for the T-cell response in celiac disease
J Proteome Res, 8 (4), 1748-55
DOI 10.1021/pr800960n, PubMed 19239248

Fallang LE, Bergseng E, Hotta K, Berg-Larsen A, Kim CY, Sollid LM (2009)
Differences in the risk of celiac disease associated with HLA-DQ2.5 or HLA-DQ2.2 are related to sustained gluten antigen presentation
Nat Immunol, 10 (10), 1096-101
DOI 10.1038/ni.1780, PubMed 19718029

Jabri B, Sollid LM (2009)
Tissue-mediated control of immunopathology in coeliac disease
Nat Rev Immunol, 9 (12), 858-70
DOI 10.1038/nri2670, PubMed 19935805

Olsen I, Tollefsen S, Aagaard C, Reitan LJ, Bannantine JP, Andersen P, Sollid LM, Lundin KE (2009)
Isolation of Mycobacterium avium subspecies paratuberculosis reactive CD4 T cells from intestinal biopsies of Crohn's disease patients
PLoS One, 4 (5), e5641
DOI 10.1371/journal.pone.0005641, PubMed 19479064

Qiao SW, Sollid LM, Blumberg RS (2009)
Antigen presentation in celiac disease
Curr Opin Immunol, 21 (1), 111-7
DOI 10.1016/j.coi.2009.03.004, PubMed 19342211

Stenman SM, Venäläinen JI, Lindfors K, Auriola S, Mauriala T, Kaukovirta-Norja A, Jantunen A, Laurila K, Qiao SW, Sollid LM, Männisto PT, Kaukinen K, Mäki M (2009)
Enzymatic detoxification of gluten by germinating wheat proteases: implications for new treatment of celiac disease
Ann Med, 41 (5), 390-400
DOI 10.1080/07853890902878138, PubMed 19353359

Stensland ME, Pollmann S, Molberg Ø, Sollid LM, Fleckenstein B (2009)
Primary sequence, together with other factors, influence peptide deimination by peptidylarginine deiminase-4
Biol Chem, 390 (2), 99-107
DOI 10.1515/BC.2009.019, PubMed 19040354

Publications 2008

Adamovic S, Amundsen SS, Lie BA, Gudjónsdóttir AH, Ascher H, Ek J, van Heel DA, Nilsson S, Sollid LM, Torinsson Naluai A (2008)
Association study of IL2/IL21 and FcgRIIa: significant association with the IL2/IL21 region in Scandinavian coeliac disease families
Genes Immun, 9 (4), 364-7
DOI 10.1038/gene.2008.27, PubMed 18418394

Bergseng E, Sidney J, Sette A, Sollid LM (2008)
Analysis of the binding of gluten T-cell epitopes to various human leukocyte antigen class II molecules
Hum Immunol, 69 (2), 94-100
DOI 10.1016/j.humimm.2008.01.002, PubMed 18361933

Fallang LE, Roh S, Holm A, Bergseng E, Yoon T, Fleckenstein B, Bandyopadhyay A, Mellins ED, Sollid LM (2008)
Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM
J Immunol, 181 (8), 5451-5461
DOI 10.4049/jimmunol.181.8.5451, PubMed 18832702

Hovhannisyan Z, Weiss A, Martin A, Wiesner M, Tollefsen S, Yoshida K, Ciszewski C, Curran SA, Murray JA, David CS, Sollid LM, Koning F, Teyton L, Jabri B (2008)
The role of HLA-DQ8 beta57 polymorphism in the anti-gluten T-cell response in coeliac disease
Nature, 456 (7221), 534-8
DOI 10.1038/nature07524, PubMed 19037317

Jüse U, Fleckenstein B, Bergseng E, Sollid LM (2008)
Soluble HLA-DQ2 expressed in S2 cells copurifies with a high affinity insect cell derived protein
Immunogenetics, 61 (2), 81-9
DOI 10.1007/s00251-008-0338-7, PubMed 18987854

Qiao SW, Kobayashi K, Johansen FE, Sollid LM, Andersen JT, Milford E, Roopenian DC, Lencer WI, Blumberg RS (2008)
Dependence of antibody-mediated presentation of antigen on FcRn
Proc Natl Acad Sci U S A, 105 (27), 9337-42
DOI 10.1073/pnas.0801717105, PubMed 18599440

Sollid LM (2008)
Hunting for celiac disease genes
Gastroenterology, 134 (3), 869-71
DOI 10.1053/j.gastro.2008.01.020, PubMed 18325395

Sollid LM, Johansen FE (2008)
Animal models of inflammatory bowel disease at the dawn of the new genetics era
PLoS Med, 5 (9), e198
DOI 10.1371/journal.pmed.0050198, PubMed 18828669

Sollid LM, Lundin KE (2008)
Diagnosis and treatment of celiac disease
Mucosal Immunol, 2 (1), 3-7
DOI 10.1038/mi.2008.74, PubMed 19079329

Stamnaes J, Fleckenstein B, Lund-Johansen F, Sollid LM (2008)
The monoclonal antibody 6B9 recognizes CD44 and not cell surface transglutaminase 2
Scand J Immunol, 68 (5), 534-42
DOI 10.1111/j.1365-3083.2008.02173.x, PubMed 18803608

Stamnaes J, Fleckenstein B, Sollid LM (2008)
The propensity for deamidation and transamidation of peptides by transglutaminase 2 is dependent on substrate affinity and reaction conditions
Biochim Biophys Acta, 1784 (11), 1804-11
DOI 10.1016/j.bbapap.2008.08.011, PubMed 18793760

Tunheim G, Schjetne KW, Rasmussen IB, Sollid LM, Sandlie I, Bogen B (2008)
Recombinant antibodies for delivery of antigen: a single loop between beta-strands in the constant region can accommodate long, complex and tandem T cell epitopes
Int Immunol, 20 (3), 295-306
DOI 10.1093/intimm/dxm141, PubMed 18252695

Publications 2007

Adamovic S, Amundsen SS, Lie BA, Hellqvist A, Gudjónsdóttir AH, Ek J, Nilsson S, Wahlström J, Ascher H, Sollid LM, Naluai AT (2007)
Fine mapping study in Scandinavian families suggests association between coeliac disease and haplotypes in chromosome region 5q32
Tissue Antigens, 71 (1), 27-34
DOI 10.1111/j.1399-0039.2007.00955.x, PubMed 17971050

Amundsen SS, Adamovic S, Hellqvist A, Nilsson S, Gudjónsdóttir AH, Ascher H, Ek J, Larsson K, Wahlström J, Lie BA, Sollid LM, Naluai AT (2007)
A comprehensive screen for SNP associations on chromosome region 5q31-33 in Swedish/Norwegian celiac disease families
Eur J Hum Genet, 15 (9), 980-7
DOI 10.1038/sj.ejhg.5201870, PubMed 17551518

Ráki M, Fallang LE, Brottveit M, Bergseng E, Quarsten H, Lundin KE, Sollid LM (2007)
Tetramer visualization of gut-homing gluten-specific T cells in the peripheral blood of celiac disease patients
Proc Natl Acad Sci U S A, 104 (8), 2831-6
DOI 10.1073/pnas.0608610104, PubMed 17307878

Ráki M, Schjetne KW, Stamnaes J, Molberg Ø, Jahnsen FL, Issekutz TB, Bogen B, Sollid LM (2007)
Surface expression of transglutaminase 2 by dendritic cells and its potential role for uptake and presentation of gluten peptides to T cells
Scand J Immunol, 65 (3), 213-20
DOI 10.1111/j.1365-3083.2006.01881.x, PubMed 17309775

Xia J, Bergseng E, Fleckenstein B, Siegel M, Kim CY, Khosla C, Sollid LM (2007)
Cyclic and dimeric gluten peptide analogues inhibiting DQ2-mediated antigen presentation in celiac disease
Bioorg Med Chem, 15 (20), 6565-73
DOI 10.1016/j.bmc.2007.07.001, PubMed 17681795

Publications 2006

Amundsen SS, Monsuur AJ, Wapenaar MC, Lie BA, Ek J, Gudjónsdóttir AH, Ascher H, Wijmenga C, Sollid LM (2006)
Association analysis of MYO9B gene polymorphisms with celiac disease in a Swedish/Norwegian cohort
Hum Immunol, 67 (4-5), 341-5
DOI 10.1016/j.humimm.2006.03.020, PubMed 16720215

Amundsen SS, Vatn M, IBSEN study group, Wijmenga C, Sollid LM, Lie BA (2006)
Association analysis of MYO9B gene polymorphisms and inflammatory bowel disease in a Norwegian cohort
Tissue Antigens, 68 (3), 249-52
DOI 10.1111/j.1399-0039.2006.00665.x, PubMed 16948647

Bethune MT, Strop P, Tang Y, Sollid LM, Khosla C (2006)
Heterologous expression, purification, refolding, and structural-functional characterization of EP-B2, a self-activating barley cysteine endoprotease
Chem Biol, 13 (6), 637-47
DOI 10.1016/j.chembiol.2006.04.008, PubMed 16793521

Bjørnvold M, Amundsen SS, Stene LC, Joner G, Dahl-Jørgensen K, Njølstad PR, Ek J, Ascher H, Gudjònsdòttir AH, Lie BA, Skinningsrud B, Akselsen HE, Rønningen KS, Sollid LM, Undlien DE (2006)
FOXP3 polymorphisms in type 1 diabetes and coeliac disease
J Autoimmun, 27 (2), 140-4
DOI 10.1016/j.jaut.2006.06.007, PubMed 16996248

Holm A, Rise F, Sessler N, Sollid LM, Undheim K, Fleckenstein B (2006)
Specific modification of peptide-bound citrulline residues
Anal Biochem, 352 (1), 68-76
DOI 10.1016/j.ab.2006.02.007, PubMed 16540076

Jabri B, Sollid LM (2006)
Mechanisms of disease: immunopathogenesis of celiac disease
Nat Clin Pract Gastroenterol Hepatol, 3 (9), 516-25
DOI 10.1038/ncpgasthep0582, PubMed 16951668

Molberg Ø, Sollid LM (2006)
A gut feeling for joint inflammation - using coeliac disease to understand rheumatoid arthritis
Trends Immunol, 27 (4), 188-94
DOI 10.1016/j.it.2006.02.006, PubMed 16530013

Ráki M, Tollefsen S, Molberg Ø, Lundin KE, Sollid LM, Jahnsen FL (2006)
A unique dendritic cell subset accumulates in the celiac lesion and efficiently activates gluten-reactive T cells
Gastroenterology, 131 (2), 428-38
DOI 10.1053/j.gastro.2006.06.002, PubMed 16890596

Sollid LM, Vaage JT (2006)
Cross-dressing T cells go wild
Nat Med, 12 (6), 611-2
DOI 10.1038/nm0606-611, PubMed 16761002

Spurkland A, Sollid LM (2006)
Mapping genes and pathways in autoimmune disease
Trends Immunol, 27 (7), 336-42
DOI 10.1016/j.it.2006.05.008, PubMed 16753344

Tollefsen S, Arentz-Hansen H, Fleckenstein B, Molberg O, Ráki M, Kwok WW, Jung G, Lundin KE, Sollid LM (2006)
HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease
J Clin Invest, 116 (8), 2226-36
DOI 10.1172/JCI27620, PubMed 16878175

Xia J, Siegel M, Bergseng E, Sollid LM, Khosla C (2006)
Inhibition of HLA-DQ2-mediated antigen presentation by analogues of a high affinity 33-residue peptide from alpha2-gliadin
J Am Chem Soc, 128 (6), 1859-67
DOI 10.1021/ja056423o, PubMed 16464085

Publications 2005

Bergseng E, Xia J, Kim CY, Khosla C, Sollid LM (2005)
Main chain hydrogen bond interactions in the binding of proline-rich gluten peptides to the celiac disease-associated HLA-DQ2 molecule
J Biol Chem, 280 (23), 21791-6
DOI 10.1074/jbc.M501558200, PubMed 15826953

Fleckenstein B, Qiao SW, Larsen MR, Roepstorff P, Sollid LM, Jung G (2005)
Molecular characterization of covalent transglutaminase (TG2)-gliadin peptide complexes involved in coeliac disease
Peptides 2004, Proceedings: BRIDGES BETWEEN DISCIPLINES, 73-74

Khosla C, Gray GM, Sollid LM (2005)
Putative efficacy and dosage of prolyl endopeptidase for digesting and detoxifying gliadin peptides
Gastroenterology, 129 (4), 1362-3; author reply 1363
DOI 10.1053/j.gastro.2005.08.044, PubMed 16230098

Koning F, Schuppan D, Cerf-Bensussan N, Sollid LM (2005)
Pathomechanisms in celiac disease
Best Pract Res Clin Gastroenterol, 19 (3), 373-87
DOI 10.1016/j.bpg.2005.02.003, PubMed 15925843

Molberg O, Uhlen AK, Jensen T, Flaete NS, Fleckenstein B, Arentz-Hansen H, Raki M, Lundin KE, Sollid LM (2005)
Mapping of gluten T-cell epitopes in the bread wheat ancestors: implications for celiac disease
Gastroenterology, 128 (2), 393-401
DOI 10.1053/j.gastro.2004.11.003, PubMed 15685550

Qiao SW, Bergseng E, Molberg O, Jung G, Fleckenstein B, Sollid LM (2005)
Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: importance of proline spacing and glutamine deamidation
J Immunol, 175 (1), 254-61
DOI 10.4049/jimmunol.175.1.254, PubMed 15972656

Qiao SW, Piper J, Haraldsen G, Oynebråten I, Fleckenstein B, Molberg O, Khosla C, Sollid LM (2005)
Tissue transglutaminase-mediated formation and cleavage of histamine-gliadin complexes: biological effects and implications for celiac disease
J Immunol, 174 (3), 1657-63
DOI 10.4049/jimmunol.174.3.1657, PubMed 15661929

Ráki M, Molberg O, Tollefsen S, Lundin KE, Sollid LM (2005)
The effects of atorvastatin on gluten-induced intestinal T cell responses in coeliac disease
Clin Exp Immunol, 142 (2), 333-40
DOI 10.1111/j.1365-2249.2005.02915.x, PubMed 16232221

Shan L, Qiao SW, Arentz-Hansen H, Molberg Ø, Gray GM, Sollid LM, Khosla C (2005)
Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprue
J Proteome Res, 4 (5), 1732-41
DOI 10.1021/pr050173t, PubMed 16212427

Sollid LM (2005)
Celiac disease as a model of gastrointestinal inflammation
J Pediatr Gastroenterol Nutr, 40 Suppl 1, S41-2
DOI 10.1097/00005176-200504001-00025, PubMed 15805849

Sollid LM, Jabri B (2005)
Is celiac disease an autoimmune disorder?
Curr Opin Immunol, 17 (6), 595-600
DOI 10.1016/j.coi.2005.09.015, PubMed 16214317

Sollid LM, Khosla C (2005)
Future therapeutic options for celiac disease
Nat Clin Pract Gastroenterol Hepatol, 2 (3), 140-7
DOI 10.1038/ncpgasthep0111, PubMed 16265155

Sollid LM, Lie BA (2005)
Celiac disease genetics: current concepts and practical applications
Clin Gastroenterol Hepatol, 3 (9), 843-51
DOI 10.1016/s1542-3565(05)00532-x, PubMed 16234020

Viken MK, Amundsen SS, Kvien TK, Boberg KM, Gilboe IM, Lilleby V, Sollid LM, Førre OT, Thorsby E, Smerdel A, Lie BA (2005)
Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases
Genes Immun, 6 (3), 271-3
DOI 10.1038/sj.gene.6364178, PubMed 15759012

Xia J, Sollid LM, Khosla C (2005)
Equilibrium and kinetic analysis of the unusual binding behavior of a highly immunogenic gluten peptide to HLA-DQ2
Biochemistry, 44 (11), 4442-9
DOI 10.1021/bi047747c, PubMed 15766274

Publications 2004

Amundsen SS, Naluai AT, Ascher H, Ek J, Gudjónsdóttir AH, Wahlström J, Lie BA, Sollid LM (2004)
Genetic analysis of the CD28/CTLA4/ICOS (CELIAC3) region in coeliac disease
Tissue Antigens, 64 (5), 593-9
DOI 10.1111/j.1399-0039.2004.00312.x, PubMed 15496203

Arentz-Hansen H, Fleckenstein B, Molberg Ø, Scott H, Koning F, Jung G, Roepstorff P, Lundin KE, Sollid LM (2004)
The molecular basis for oat intolerance in patients with celiac disease
PLoS Med, 1 (1), e1
DOI 10.1371/journal.pmed.0010001, PubMed 15526039

Fleckenstein B, Qiao SW, Larsen MR, Jung G, Roepstorff P, Sollid LM (2004)
Molecular characterization of covalent complexes between tissue transglutaminase and gliadin peptides
J Biol Chem, 279 (17), 17607-16
DOI 10.1074/jbc.M310198200, PubMed 14747475

Holopainen P, Naluai AT, Moodie S, Percopo S, Coto I, Clot F, Ascher H, Sollid L, Ciclitira P, Greco L, Clerget-Darpoux F, Partanen J, Members of the European Genetics Cluster on Coeliac Disease (2004)
Candidate gene region 2q33 in European families with coeliac disease
Tissue Antigens, 63 (3), 212-22
DOI 10.1111/j.1399-0039.2004.00189.x, PubMed 14989710

Kim CY, Quarsten H, Bergseng E, Khosla C, Sollid LM (2004)
Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease
Proc Natl Acad Sci U S A, 101 (12), 4175-9
DOI 10.1073/pnas.0306885101, PubMed 15020763

Margaritte-Jeannin P, Babron MC, Bourgey M, Louka AS, Clot F, Percopo S, Coto I, Hugot JP, Ascher H, Sollid LM, Greco L, Clerget-Darpoux F (2004)
HLA-DQ relative risks for coeliac disease in European populations: a study of the European Genetics Cluster on Coeliac Disease
Tissue Antigens, 63 (6), 562-7
DOI 10.1111/j.0001-2815.2004.00237.x, PubMed 15140032

Marti T, Molberg O, Li Q, Gray GM, Khosla C, Sollid LM (2004)
Prolyl endopeptidase-mediated destruction of T cell epitopes in whole gluten: chemical and immunological characterization
J Pharmacol Exp Ther, 312 (1), 19-26
DOI 10.1124/jpet.104.073312, PubMed 15358813

Qiao SW, Bergseng E, Molberg Ø, Xia J, Fleckenstein B, Khosla C, Sollid LM (2004)
Antigen presentation to celiac lesion-derived T cells of a 33-mer gliadin peptide naturally formed by gastrointestinal digestion
J Immunol, 173 (3), 1757-62
DOI 10.4049/jimmunol.173.3.1757, PubMed 15265905

Shan L, Marti T, Sollid LM, Gray GM, Khosla C (2004)
Comparative biochemical analysis of three bacterial prolyl endopeptidases: implications for coeliac sprue
Biochem J, 383 (Pt 2), 311-8
DOI 10.1042/BJ20040907, PubMed 15245330

Sollid LM (2004)
Intraepithelial lymphocytes in celiac disease: license to kill revealed
Immunity, 21 (3), 303-4
DOI 10.1016/j.immuni.2004.08.002, PubMed 15357941

Sollid LM, Gray GM (2004)
A role for bacteria in celiac disease?
Am J Gastroenterol, 99 (5), 905-6
DOI 10.1111/j.1572-0241.2004.04158.x, PubMed 15128358

Publications 2003

Babron MC, Nilsson S, Adamovic S, Naluai AT, Wahlström J, Ascher H, Ciclitira PJ, Sollid LM, Partanen J, Greco L, Clerget-Darpoux F, European Genetics Cluster on Coeliac Disease (2003)
Meta and pooled analysis of European coeliac disease data
Eur J Hum Genet, 11 (11), 828-34
DOI 10.1038/sj.ejhg.5201051, PubMed 14571266

Karell K, Louka AS, Moodie SJ, Ascher H, Clot F, Greco L, Ciclitira PJ, Sollid LM, Partanen J, European Genetics Cluster on Celiac Disease (2003)
HLA types in celiac disease patients not carrying the DQA1*05-DQB1*02 (DQ2) heterodimer: results from the European Genetics Cluster on Celiac Disease
Hum Immunol, 64 (4), 469-77
DOI 10.1016/s0198-8859(03)00027-2, PubMed 12651074

Louka AS, Lie BA, Talseth B, Ascher H, Ek J, Gudjónsdóttir AH, Sollid LM (2003)
Coeliac disease patients carry conserved HLA-DR3-DQ2 haplotypes revealed by association of TNF alleles
Immunogenetics, 55 (5), 339-43
DOI 10.1007/s00251-003-0586-5, PubMed 12845502

Louka AS, Moodie SJ, Karell K, Bolognesi E, Ascher H, Greco L, Momigliano-Richiardi P, Partanen J, Ciclitira PJ, Sollid LM, European Genetics Cluster on Celiac Disease (2003)
A collaborative European search for non-DQA1*05-DQB1*02 celiac disease loci on HLA-DR3 haplotypes: analysis of transmission from homozygous parents
Hum Immunol, 64 (3), 350-8
DOI 10.1016/s0198-8859(02)00822-4, PubMed 12590980

Louka AS, Sollid LM (2003)
HLA in coeliac disease: unravelling the complex genetics of a complex disorder
Tissue Antigens, 61 (2), 105-17
DOI 10.1034/j.1399-0039.2003.00017.x, PubMed 12694579

Lundin KE, Farstad IN, Sollid LM (2003)
[Coeliac disease--new clinical findings and diagnostic tools]
Tidsskr Nor Laegeforen, 123 (22), 3226-9
PubMed 14714016

Lundin KE, Sollid LM (2003)
Gliadin peptide specific intestinal T cells in coeliac disease
Gut, 52 (2), 162
DOI 10.1136/gut.52.2.162, PubMed 12524389

Molberg Ø, Solheim Flaete N, Jensen T, Lundin KE, Arentz-Hansen H, Anderson OD, Kjersti Uhlen A, Sollid LM (2003)
Intestinal T-cell responses to high-molecular-weight glutenins in celiac disease
Gastroenterology, 125 (2), 337-44
DOI 10.1016/s0016-5085(03)00890-4, PubMed 12891534

Sollid LM, Lundin KE (2003)
[Disease mechanisms in coeliac disease]
Tidsskr Nor Laegeforen, 123 (22), 3230-3
PubMed 14714017

Publications 2002

Arentz-Hansen H, McAdam SN, Molberg Ø, Fleckenstein B, Lundin KE, Jørgensen TJ, Jung G, Roepstorff P, Sollid LM (2002)
Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues
Gastroenterology, 123 (3), 803-9
DOI 10.1053/gast.2002.35381, PubMed 12198706

Fleckenstein B, Molberg Ø, Qiao SW, Schmid DG, von der Mülbe F, Elgstøen K, Jung G, Sollid LM (2002)
Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the transamidation versus deamidation process
J Biol Chem, 277 (37), 34109-16
DOI 10.1074/jbc.M204521200, PubMed 12093810

Louka AS, Nilsson S, Olsson M, Talseth B, Lie BA, Ek J, Gudjónsdóttir AH, Ascher H, Sollid LM (2002)
HLA in coeliac disease families: a novel test of risk modification by the 'other' haplotype when at least one DQA1*05-DQB1*02 haplotype is carried
Tissue Antigens, 60 (2), 147-54
DOI 10.1034/j.1399-0039.2002.600205.x, PubMed 12392509

Louka AS, Stensby EK, Ek J, Gudjónsdóttir AH, Ascher H, Sollid LM (2002)
Coeliac disease candidate genes: no association with functional polymorphisms in matrix metalloproteinase 1 and 3 gene promoters
Scand J Gastroenterol, 37 (8), 931-5
DOI 10.1080/003655202760230892, PubMed 12229968

Louka AS, Torinsson Naluai A, D'Alfonso S, Ascher H, Coto I, Ek J, Giordano M, Gudjónsdóttir AH, Mellai M, Momigliano-Richiardi P, Percopo S, Samuelsson L, Wahlström J, Greco L, Sollid LM (2002)
The IL12B gene does not confer susceptibility to coeliac disease
Tissue Antigens, 59 (1), 70-2
DOI 10.1034/j.1399-0039.2002.590117.x, PubMed 11972887

Lunde E, Lauvrak V, Rasmussen IB, Schjetne KW, Thompson KM, Michaelsen TE, Brekke OH, Sollid LM, Bogen B, Sandlie I (2002)
Troybodies and pepbodies
Biochem Soc Trans, 30 (4), 500-6
DOI 10.1042/bst0300500, PubMed 12196123

Schjetne KW, Thompson KM, Aarvak T, Fleckenstein B, Sollid LM, Bogen B (2002)
A mouse C kappa-specific T cell clone indicates that DC-SIGN is an efficient target for antibody-mediated delivery of T cell epitopes for MHC class II presentation
Int Immunol, 14 (12), 1423-30
DOI 10.1093/intimm/dxf110, PubMed 12456590

Shan L, Molberg Ø, Parrot I, Hausch F, Filiz F, Gray GM, Sollid LM, Khosla C (2002)
Structural basis for gluten intolerance in celiac sprue
Science, 297 (5590), 2275-9
DOI 10.1126/science.1074129, PubMed 12351792

Sollid LM (2002)
Coeliac disease: dissecting a complex inflammatory disorder
Nat Rev Immunol, 2 (9), 647-55
DOI 10.1038/nri885, PubMed 12209133

Sollid LM (2002)
Breast milk against coeliac disease
Gut, 51 (6), 767-8
DOI 10.1136/gut.51.6.767, PubMed 12427772

Publications 2001

McAdam SN, Fleckenstein B, Rasmussen IB, Schmid DG, Sandlie I, Bogen B, Viner NJ, Sollid LM (2001)
T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation
J Exp Med, 193 (11), 1239-46
DOI 10.1084/jem.193.11.1239, PubMed 11390431

Molberg O, McAdam S, Lundin KE, Kristiansen C, Arentz-Hansen H, Kett K, Sollid LM (2001)
T cells from celiac disease lesions recognize gliadin epitopes deamidated in situ by endogenous tissue transglutaminase
Eur J Immunol, 31 (5), 1317-23
DOI 10.1002/1521-4141(200105)31:5<1317::AID-IMMU1317>3.0.CO;2-I, PubMed 11465088

Naluai AT, Nilsson S, Gudjónsdóttir AH, Louka AS, Ascher H, Ek J, Hallberg B, Samuelsson L, Kristiansson B, Martinsson T, Nerman O, Sollid LM, Wahlström J (2001)
Genome-wide linkage analysis of Scandinavian affected sib-pairs supports presence of susceptibility loci for celiac disease on chromosomes 5 and 11
Eur J Hum Genet, 9 (12), 938-44
DOI 10.1038/sj.ejhg.5200752, PubMed 11840196

Quarsten H, McAdam SN, Jensen T, Arentz-Hansen H, Molberg Ø, Lundin KE, Sollid LM (2001)
Staining of celiac disease-relevant T cells by peptide-DQ2 multimers
J Immunol, 167 (9), 4861-8
DOI 10.4049/jimmunol.167.9.4861, PubMed 11673490

Sollid LM, Lundin KE (2001)
Coeliac disease. An inappropriate immune response
Lancet, 358 Suppl, S13
DOI 10.1016/s0140-6736(01)07026-x, PubMed 11784562

Sollid LM, McAdam SN, Molberg O, Quarsten H, Arentz-Hansen H, Louka AS, Lundin KE (2001)
Genes and environment in celiac disease
Acta Odontol Scand, 59 (3), 183-6
DOI 10.1080/000163501750266792, PubMed 11501889

Publications 2000

Arentz-Hansen EH, McAdam SN, Molberg O, Kristiansen C, Sollid LM (2000)
Production of a panel of recombinant gliadins for the characterisation of T cell reactivity in coeliac disease
Gut, 46 (1), 46-51
DOI 10.1136/gut.46.1.46, PubMed 10601054

Arentz-Hansen H, Körner R, Molberg O, Quarsten H, Vader W, Kooy YM, Lundin KE, Koning F, Roepstorff P, Sollid LM, McAdam SN (2000)
The intestinal T cell response to alpha-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase
J Exp Med, 191 (4), 603-12
DOI 10.1084/jem.191.4.603, PubMed 10684852

McAdam SN, Sollid LM (2000)
Getting to grips with gluten
Gut, 47 (6), 743-5
DOI 10.1136/gut.47.6.743, PubMed 11076867

Molberg O, McAdam SN, Lundin KE, Sollid LM (2000)
Studies of gliadin-specific T-cells in celiac disease
Methods Mol Med, 41, 105-24
DOI 10.1385/1-59259-082-9:105, PubMed 21374436

Molberg O, McAdam SN, Sollid LM (2000)
Role of tissue transglutaminase in celiac disease
J Pediatr Gastroenterol Nutr, 30 (3), 232-40
DOI 10.1097/00005176-200003000-00005, PubMed 10749404

Naluai AT, Nilsson S, Samuelsson L, Gudjónsdóttir AH, Ascher H, Ek J, Hallberg B, Kristiansson B, Martinsson T, Nerman O, Sollid LM, Wahlström J (2000)
The CTLA4/CD28 gene region on chromosome 2q33 confers susceptibility to celiac disease in a way possibly distinct from that of type 1 diabetes and other chronic inflammatory disorders
Tissue Antigens, 56 (4), 350-5
DOI 10.1034/j.1399-0039.2000.560407.x, PubMed 11098935

Sollid LM (2000)
Molecular basis of celiac disease
Annu Rev Immunol, 18, 53-81
DOI 10.1146/annurev.immunol.18.1.53, PubMed 10837052

Publications 1999

Lie BA, Sollid LM, Ascher H, Ek J, Akselsen HE, Rønningen KS, Thorsby E, Undlien DE (1999)
A gene telomeric of the HLA class I region is involved in predisposition to both type 1 diabetes and coeliac disease
Tissue Antigens, 54 (2), 162-8
DOI 10.1034/j.1399-0039.1999.540207.x, PubMed 10488743

Quarsten H, Molberg O, Fugger L, McAdam SN, Sollid LM (1999)
HLA binding and T cell recognition of a tissue transglutaminase-modified gliadin epitope
Eur J Immunol, 29 (8), 2506-14
DOI 10.1002/(SICI)1521-4141(199908)29:08<2506::AID-IMMU2506>3.0.CO;2-9, PubMed 10458765

Publications 1998

Haraldsen G, Sollid LM, Bakke O, Farstad IN, Kvale D, Molberg, Norstein J, Stang E, Brandtzaeg P (1998)
Major histocompatibility complex class II-dependent antigen presentation by human intestinal endothelial cells
Gastroenterology, 114 (4), 649-56
DOI 10.1016/s0016-5085(98)70578-5, PubMed 9516385

Molberg O, Lundin KE, Nilsen EM, Scott H, Kett K, Brandtzaeg P, Thorsby E, Sollid LM (1998)
HLA restriction patterns of gliadin- and astrovirus-specific CD4+ T cells isolated in parallel from the small intestine of celiac disease patients
Tissue Antigens, 52 (5), 407-15
DOI 10.1111/j.1399-0039.1998.tb03066.x, PubMed 9864029

Molberg O, Mcadam SN, Körner R, Quarsten H, Kristiansen C, Madsen L, Fugger L, Scott H, Norén O, Roepstorff P, Lundin KE, Sjöström H, Sollid LM (1998)
Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease
Nat Med, 4 (6), 713-7
DOI 10.1038/nm0698-713, PubMed 9623982

Molberg O, Nilsen EM, Sollid LM, Scott H, Brandtzaeg P, Thorsby E, Lundin KE (1998)
CD4+ T cells with specific reactivity against astrovirus isolated from normal human small intestine
Gastroenterology, 114 (1), 115-22
DOI 10.1016/s0016-5085(98)70639-0, PubMed 9428225

Nilsen EM, Jahnsen FL, Lundin KE, Johansen FE, Fausa O, Sollid LM, Jahnsen J, Scott H, Brandtzaeg P (1998)
Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease
Gastroenterology, 115 (3), 551-63
DOI 10.1016/s0016-5085(98)70134-9, PubMed 9721152

Quarsten H, Paulsen G, Johansen BH, Thorpe CJ, Holm A, Buus S, Sollid LM (1998)
The P9 pocket of HLA-DQ2 (non-Aspbeta57) has no particular preference for negatively charged anchor residues found in other type 1 diabetes-predisposing non-Aspbeta57 MHC class II molecules
Int Immunol, 10 (8), 1229-36
DOI 10.1093/intimm/10.8.1229, PubMed 9723710

Sjöström H, Lundin KE, Molberg O, Körner R, McAdam SN, Anthonsen D, Quarsten H, Norén O, Roepstorff P, Thorsby E, Sollid LM (1998)
Identification of a gliadin T-cell epitope in coeliac disease: general importance of gliadin deamidation for intestinal T-cell recognition
Scand J Immunol, 48 (2), 111-5
DOI 10.1046/j.1365-3083.1998.00397.x, PubMed 9716100

Sollid LM (1998)
Genetics of the immune response to gluten in coeliac disease
Dig Dis, 16 (6), 345-7
DOI 10.1159/000016889, PubMed 10207220

Sollid LM, Scott H (1998)
New tool to predict celiac disease on its way to the clinics
Gastroenterology, 115 (6), 1584-6
DOI 10.1016/s0016-5085(98)70040-x, PubMed 9834289

Straumfors A, Johansen BH, Vartdal F, Sollid LM, Thorsby E, Buus S (1998)
A peptide-binding assay for the disease-associated HLA-DQ8 molecule
Scand J Immunol, 47 (6), 561-7
DOI 10.1046/j.1365-3083.1998.00342.x, PubMed 9652824

van de Wal Y, Kooy YM, van Veelen PA, Peña SA, Mearin LM, Molberg O, Lundin KE, Sollid LM, Mutis T, Benckhuijsen WE, Drijfhout JW, Koning F (1998)
Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin
Proc Natl Acad Sci U S A, 95 (17), 10050-4
DOI 10.1073/pnas.95.17.10050, PubMed 9707598

Publications 1997

Lundin KE, Sollid LM, Anthonsen D, Norén O, Molberg O, Thorsby E, Sjöström H (1997)
Heterogeneous reactivity patterns of HLA-DQ-restricted, small intestinal T-cell clones from patients with celiac disease
Gastroenterology, 112 (3), 752-9
DOI 10.1053/gast.1997.v112.pm9041236, PubMed 9041236

Molberg O, Kett K, Scott H, Thorsby E, Sollid LM, Lundin KE (1997)
Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls
Scand J Immunol, 46 (1), 103-8
PubMed 9246215

Molberg O, Kett K, Scott H, Thorsby E, Sollid LM, Lundin KE (1997)
Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls
Scand J Immunol, 46 (3), 103-9
DOI 10.1046/j.1365-3083.1997.d01-93.x, PubMed 9315123

Scott H, Nilsen E, Sollid LM, Lundin KE, Rugtveit J, Molberg O, Thorsby E, Brandtzaeg P (1997)
Immunopathology of gluten-sensitive enteropathy
Springer Semin Immunopathol, 18 (4), 535-53
DOI 10.1007/BF00824057, PubMed 9144869

Sollid LM, Molberg O, McAdam S, Lundin KE (1997)
Autoantibodies in coeliac disease: tissue transglutaminase--guilt by association?
Gut, 41 (6), 851-2
DOI 10.1136/gut.41.6.851, PubMed 9462222

Spurkland A, Ingvarsson G, Falk ES, Knutsen I, Sollid LM, Thorsby E (1997)
Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA-DQ (alpha 1*0501, beta 1*02) or the HLA-DQ (alpha 1*03, beta 1*0302) heterodimers
Tissue Antigens, 49 (1), 29-34
DOI 10.1111/j.1399-0039.1997.tb02706.x, PubMed 9027962

Publications 1996

Johansen BH, Gjertsen HA, Vartdal F, Buus S, Thorsby E, Lundin KE, Sollid LM (1996)
Binding of peptides from the N-terminal region of alpha-gliadin to the celiac disease-associated HLA-DQ2 molecule assessed in biochemical and T cell assays
Clin Immunol Immunopathol, 79 (3), 288-93
DOI 10.1006/clin.1996.0081, PubMed 8635288

Johansen BH, Jensen T, Thorpe CJ, Vartdal F, Thorsby E, Sollid LM (1996)
Both alpha and beta chain polymorphisms determine the specificity of the disease-associated HLA-DQ2 molecules, with beta chain residues being most influential
Immunogenetics, 45 (2), 142-50
DOI 10.1007/s002510050182, PubMed 8952964

Johansen BH, Vartdal F, Eriksen JA, Thorsby E, Sollid LM (1996)
Identification of a putative motif for binding of peptides to HLA-DQ2
Int Immunol, 8 (2), 177-82
DOI 10.1093/intimm/8.2.177, PubMed 8671602

Ploski R, Ascher H, Sollid LM (1996)
HLA genotypes and the increased incidence of coeliac disease in Sweden
Scand J Gastroenterol, 31 (11), 1092-7
DOI 10.3109/00365529609036892, PubMed 8938902

Vartdal F, Johansen BH, Friede T, Thorpe CJ, Stevanović S, Eriksen JE, Sletten K, Thorsby E, Rammensee HG, Sollid LM (1996)
The peptide binding motif of the disease associated HLA-DQ (alpha 1* 0501, beta 1* 0201) molecule
Eur J Immunol, 26 (11), 2764-72
DOI 10.1002/eji.1830261132, PubMed 8921967

Publications 1995

Jensen K, Sollid LM, Scott H, Paulsen G, Kett K, Thorsby E, Lundin KE (1995)
Gliadin-specific T cell responses in peripheral blood of healthy individuals involve T cells restricted by the coeliac disease associated DQ2 heterodimer
Scand J Immunol, 42 (1), 166-70
DOI 10.1111/j.1365-3083.1995.tb03640.x, PubMed 7543212

Mignot E, Kimura A, Abbal M, Thorsby E, Lin X, Voros A, Macaubas C, Bouissou F, Sollid LM, Cambon-Thomsen A (1995)
DQCAR microsatellite polymorphisms in three selected HLA class II-associated diseases
Tissue Antigens, 46 (4), 299-304
DOI 10.1111/j.1399-0039.1995.tb02496.x, PubMed 8560448

Nilsen EM, Lundin KE, Krajci P, Scott H, Sollid LM, Brandtzaeg P (1995)
Gluten specific, HLA-DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or Th0 profile dominated by interferon gamma
Gut, 37 (6), 766-76
DOI 10.1136/gut.37.6.766, PubMed 8537046

Paulsen G, Lundin KE, Gjertsen HA, Hansen T, Sollid LM, Thorsby E (1995)
HLA-DQ2-restricted T-cell recognition of gluten-derived peptides in celiac disease. Influence of amino acid substitutions in the membrane distal domain of DQ beta 1*0201
Hum Immunol, 42 (2), 145-53
DOI 10.1016/0198-8859(94)00086-6, PubMed 7744618

Przemioslo RT, Lundin KE, Sollid LM, Nelufer J, Ciclitira PJ (1995)
Histological changes in small bowel mucosa induced by gliadin sensitive T lymphocytes can be blocked by anti-interferon gamma antibody
Gut, 36 (6), 874-9
DOI 10.1136/gut.36.6.874, PubMed 7615276

Viken HD, Paulsen G, Drover S, Marshall WH, Sollid LM, Gaudernack G, Thorsby E (1995)
Influence on antibody recognition of amino acid substitutions in the cleft of HLA-DQ2 molecules. Suggestive evidence of peptide-dependent epitopes
Hum Immunol, 44 (2), 63-9
DOI 10.1016/0198-8859(95)00047-8, PubMed 8847230

Viken HD, Paulsen G, Sollid LM, Lundin KE, Tjønnfjord GE, Thorsby E, Gaudernack G (1995)
Characterization of an HLA-DQ2-specific monoclonal antibody. Influence of amino acid substitutions in DQ beta 1*0202
Hum Immunol, 42 (4), 319-27
DOI 10.1016/0198-8859(94)00110-c, PubMed 7558917

Publications 1994

Gjertsen HA, Lundin KE, Sollid LM, Eriksen JA, Thorsby E (1994)
T cells recognize a peptide derived from alpha-gliadin presented by the celiac disease-associated HLA-DQ (alpha 1*0501, beta 1*0201) heterodimer
Hum Immunol, 39 (4), 243-52
DOI 10.1016/0198-8859(94)90267-4, PubMed 7520895

Gjertsen HA, Sollid LM, Ek J, Thorsby E, Lundin KE (1994)
T cells from the peripheral blood of coeliac disease patients recognize gluten antigens when presented by HLA-DR, -DQ, or -DP molecules
Scand J Immunol, 39 (6), 567-74
DOI 10.1111/j.1365-3083.1994.tb03414.x, PubMed 8009173

Johansen BH, Buus S, Vartdal F, Viken H, Eriksen JA, Thorsby E, Sollid LM (1994)
Binding of peptides to HLA-DQ molecules: peptide binding properties of the disease-associated HLA-DQ(alpha 1*0501, beta 1*0201) molecule
Int Immunol, 6 (3), 453-61
DOI 10.1093/intimm/6.3.453, PubMed 8186196

Johansen BH, Gedde-Dahl T, Sollid LM, Vartdal F, Thorsby E, Gaudernack G (1994)
Binding of ras oncogene peptides to purified HLA-DQ (alpha 1*0102, beta 1*0602) and -DR (alpha, beta 1*0101) molecules
Scand J Immunol, 40 (4), 468
DOI 10.1111/j.1365-3083.1994.tb03491.x, PubMed 7939420

Johansen BH, Gedde-Dahl T, Sollid LM, Vartdal F, Thorsby E, Gaudernack G (1994)
Binding of ras oncogene peptides to purified HLA-DQ(alpha 1*0102,beta 1*0602) and -DR(alpha,beta 1*0101) molecules
Scand J Immunol, 39 (6), 607-12
DOI 10.1111/j.1365-3083.1994.tb03420.x, PubMed 8009176

Lundin KE, Gjertsen HA, Scott H, Sollid LM, Thorsby E (1994)
Function of DQ2 and DQ8 as HLA susceptibility molecules in celiac disease
Hum Immunol, 41 (1), 24-7
DOI 10.1016/0198-8859(94)90079-5, PubMed 7836060

Lundin KE, Scott H, Fausa O, Thorsby E, Sollid LM (1994)
T cells from the small intestinal mucosa of a DR4, DQ7/DR4, DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8
Hum Immunol, 41 (4), 285-91
DOI 10.1016/0198-8859(94)90047-7, PubMed 7883596

Publications 1993

Lundin KE, Scott H, Hansen T, Paulsen G, Halstensen TS, Fausa O, Thorsby E, Sollid LM (1993)
Gliadin-specific, HLA-DQ(alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients
J Exp Med, 178 (1), 187-96
DOI 10.1084/jem.178.1.187, PubMed 8315377

Ploski R, Ek J, Thorsby E, Sollid LM (1993)
On the HLA-DQ(alpha 1*0501, beta 1*0201)-associated susceptibility in celiac disease: a possible gene dosage effect of DQB1*0201
Tissue Antigens, 41 (4), 173-7
DOI 10.1111/j.1399-0039.1993.tb01998.x, PubMed 8362409

Sollid LM, Thorsby E (1993)
HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis
Gastroenterology, 105 (3), 910-22
DOI 10.1016/0016-5085(93)90912-v, PubMed 8359659

Publications 1992

Spurkland A, Sollid LM, Polanco I, Vartdal F, Thorsby E (1992)
HLA-DR and -DQ genotypes of celiac disease patients serologically typed to be non-DR3 or non-DR5/7
Hum Immunol, 35 (3), 188-92
DOI 10.1016/0198-8859(92)90104-u, PubMed 1293082

Thrane PS, Sollid LM, Haanes HR, Brandtzaeg P (1992)
Clustering of IgA-producing immunocytes related to HLA-DR-positive ducts in normal and inflamed salivary glands
Scand J Immunol, 35 (1), 43-51
DOI 10.1111/j.1365-3083.1992.tb02832.x, PubMed 1734495

Publications 1991

Brandtzaeg P, Bengtsson U, Halstensen TS, Hvatum M, Kett K, Rognum TO, Scott H, Sollid LM (1991)
Mucosal immunology and food antigens
Bibl Nutr Dieta (48), 30-54
DOI 10.1159/000420035, PubMed 1930122

Ronningen KS, Spurkland A, Iwe T, Sollid LM, Vartdal F, Thorsby E (1991)
Novel HLA-DR2 and -DR3 haplotypes among Norwegian Caucasians
Tissue Antigens, 37 (4), 165-7
DOI 10.1111/j.1399-0039.1991.tb01866.x, PubMed 1926125

Sollid LM (1991)
Coeliac disease: a study of immunogenetics and immunopathogenesis
Institute of Transplantation Immunology and Laboratory forImmunohistochemistry and Immunopathology (LIIPAT), Instituteof Pathology, University of Oslo, Rikshospitalet, Oslo, 1 b. (flere pag.)
BIBSYS 920113192, ISBN 82-7633-015-0

Publications 1990

Lundin KE, Sollid LM, Bosnes V, Gaudernack G, Thorsby E (1990)
T-cell recognition of HLA class II molecules induced by gamma-interferon on a colonic adenocarcinoma cell line (HT29)
Scand J Immunol, 31 (4), 469-75
DOI 10.1111/j.1365-3083.1990.tb02794.x, PubMed 2110380

Lundin KE, Sollid LM, Qvigstad E, Markussen G, Gjertsen HA, Ek J, Thorsby E (1990)
T lymphocyte recognition of a celiac disease-associated cis- or trans-encoded HLA-DQ alpha/beta-heterodimer
J Immunol, 145 (1), 136-9
PubMed 1972714

Sollid LM, Thorsby E (1990)
The primary association of celiac disease to a given HLA-DQ alpha/beta heterodimer explains the divergent HLA-DR associations observed in various Caucasian populations
Tissue Antigens, 36 (3), 136-7
DOI 10.1111/j.1399-0039.1990.tb01816.x, PubMed 2278049

Spurkland A, Sollid LM, Rønningen KS, Bosnes V, Ek J, Vartdal F, Thorsby E (1990)
Susceptibility to develop celiac disease is primarily associated with HLA-DQ alleles
Hum Immunol, 29 (3), 157-65
DOI 10.1016/0198-8859(90)90111-2, PubMed 1980918

Thrane PS, Roop DR, Sollid LM, Huitfeldt HS, Brandtzaeg P (1990)
Two-colour immunofluorescence marker study of pleomorphic adenomas
Histochemistry, 93 (5), 459-68
DOI 10.1007/BF00266401, PubMed 2158957

Thrane PS, Sollid LM, Brandtzaeg P (1990)
Abundant dendritic cells express HLA-DR in pleomorphic adenomas
Virchows Arch B Cell Pathol Incl Mol Pathol, 59 (4), 195-203
DOI 10.1007/BF02899405, PubMed 1980169

Publications 1989

Brandtzaeg P, Bosnes V, Halstensen TS, Scott H, Sollid LM, Valnes KN (1989)
T lymphocytes in human gut epithelium preferentially express the alpha/beta antigen receptor and are often CD45/UCHL1-positive
Scand J Immunol, 30 (1), 123-8
DOI 10.1111/j.1365-3083.1989.tb01196.x, PubMed 2526965

Brandtzaeg P, Halstensen TS, Kett K, Krajci P, Kvale D, Rognum TO, Scott H, Sollid LM (1989)
Immunobiology and immunopathology of human gut mucosa: humoral immunity and intraepithelial lymphocytes
Gastroenterology, 97 (6), 1562-84
DOI 10.1016/0016-5085(89)90406-x, PubMed 2684725

Lundin KE, Ovigstad E, Sollid LM, Gjertsen HA, Gaudernack G, Thorsby E (1989)
Positive selection of Tac- (CD25) positive cells following T-cell activation. Use of immunomagnetic separation and implications for T-cell cloning
J Immunogenet, 16 (2), 185-91
DOI 10.1111/j.1744-313x.1989.tb00461.x, PubMed 2687389

Lundin KE, Qvigstad E, Sollid LM, Thorsby E (1989)
Alloreactive T cells recognizing determinants dependent on the DQ beta chain of DQw2
Tissue Antigens, 34 (5), 312-6
DOI 10.1111/j.1399-0039.1989.tb01748.x, PubMed 2483467

Sollid LM, Markussen G, Ek J, Gjerde H, Vartdal F, Thorsby E (1989)
Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer
J Exp Med, 169 (1), 345-50
DOI 10.1084/jem.169.1.345, PubMed 2909659

Thorsby E, Lundin KE, Rønningen KS, Sollid LM, Vartdal F (1989)
Molecular basis and functional importance of some disease-associated HLA polymorphisms
Tissue Antigens, 34 (1), 39-49
DOI 10.1111/j.1399-0039.1989.tb01716.x, PubMed 2683208

Vartdal F, Rønningen KS, Sollid LM, Thorsby E (1989)
[Gene technology in immunologic research, diagnosis and treatment]
Tidsskr Nor Laegeforen, 109 (30), 3111-4
PubMed 2683198

Vartdal F, Sollid LM, Vandvik B, Markussen G, Thorsby E (1989)
Patients with multiple sclerosis carry DQB1 genes which encode shared polymorphic amino acid sequences
Hum Immunol, 25 (2), 103-10
DOI 10.1016/0198-8859(89)90074-8, PubMed 2737928

Publications 1988

Brandtzaeg P, Kvale D, Sollid LM, Thrane PS (1988)
The poly-Ig receptor--functional aspects of secretory component expression
Adv Exp Med Biol, 237, 9-20
DOI 10.1007/978-1-4684-5535-9_2, PubMed 3151046

Brandtzaeg P, Sollid LM, Bjerke K, Kett K, Kvale D, Rognum TO, Scott H, Thrane PS (1988)
Interactions of lymphoid cells with the epithelial environment
Monogr Allergy, 24, 51-9
PubMed 3163099

Brandtzaeg P, Sollid LM, Thrane PS, Kvale D, Bjerke K, Scott H, Kett K, Rognum TO (1988)
Lymphoepithelial interactions in the mucosal immune system
Gut, 29 (8), 1116-30
DOI 10.1136/gut.29.8.1116, PubMed 3044933

Kvale D, Bartek J, Sollid LM, Brandtzaeg P (1988)
Rapid selection of cultured cells with increased expression of a membrane marker (secretory component)
Int J Cancer, 42 (4), 638-41
DOI 10.1002/ijc.2910420428, PubMed 2459074

Kvale D, Løvhaug D, Sollid LM, Brandtzaeg P (1988)
Tumor necrosis factor-alpha up-regulates expression of secretory component, the epithelial receptor for polymeric Ig
J Immunol, 140 (9), 3086-9
PubMed 3361127

Lundin KE, Gaudernack G, Qvigstad E, Sollid LM, Thorsby E (1988)
T lymphocyte clones recognizing an HLA-DQw3.2-associated epitope involving residue 57 on the DQ beta chain
Hum Immunol, 22 (4), 235-46
DOI 10.1016/0198-8859(88)90003-1, PubMed 2459088

Markussen G, Rønningen KS, Paulsen G, Gaudernack G, Sollid LM, Thorsby E (1988)
HLA-DQw3.1 and DQw3.2 associated exon polymorphisms detected by oligonucleotide probes
Tissue Antigens, 31 (4), 204-10
DOI 10.1111/j.1399-0039.1988.tb02082.x, PubMed 3406934

Scott H, Sollid LM, Brandtzaeg P (1988)
Expression of MHC class II determinants by jejunal epithelium in coeliac disease
J Pediatr Gastroenterol Nutr, 7 (1), 145-6
DOI 10.1097/00005176-198801000-00027, PubMed 3335977

Scott H, Sollid LM, Brandtzaeg P, Thorsby E (1988)
Jejunal epithelium of patients with coeliac disease shows enhanced expression of MHC class II subregion products
Adv Exp Med Biol, 237, 689-93
DOI 10.1007/978-1-4684-5535-9_103, PubMed 3075870

Sollid LM, Brandtzaeg P, Kvale D, Gaudernack G, Scott H, Thorsby E (1988)
T cell-epithelium interactions in relation to gut immunity
Monogr Allergy, 24, 60-5
PubMed 3129651

Sollid LM, Thrane PS, Brandtzaeg P (1988)
[Cancer and immune defense]
Tidsskr Nor Laegeforen, 108 (15), 1205-9
PubMed 3291190

Publications 1987

Brandtzaeg P, Bjerke K, Kett K, Kvale D, Rognum TO, Scott H, Sollid LM, Valnes K (1987)
Production and secretion of immunoglobulins in the gastrointestinal tract
Ann Allergy, 59 (5 Pt 2), 21-39
PubMed 3318585

Kolberg J, Wedege E, Sollid L (1987)
Immunoblotting detection of lectins in gluten and white rice flour
Biochem Biophys Res Commun, 142 (3), 717-23
DOI 10.1016/0006-291x(87)91473-2, PubMed 3827897

Paulsen G, Markussen G, Sollid L, Thorsby E (1987)
Determination of the HLA-DR profile of an HLA class II negative carcinoma cell line by restriction fragment length polymorphism (RFLP) analysis
Tissue Antigens, 29 (4), 186-94
DOI 10.1111/j.1399-0039.1987.tb01575.x, PubMed 2887045

Scott H, Sollid LM, Fausa O, Brandtzaeg P, Thorsby E (1987)
Expression of major histocompatibility complex class II subregion products by jejunal epithelium in patients with coeliac disease
Scand J Immunol, 26 (5), 563-71
DOI 10.1111/j.1365-3083.1987.tb02290.x, PubMed 3500504

Sollid L, Paulsen G, Gaudernack G, Thorsby E (1987)
HLA class II profile of a human carcinoma cell line: detection on genomic level and after exposure to gamma-interferon
Transplant Proc, 19 (1 Pt 1), 215
PubMed 3152692

Sollid LM, Gaudernack G, Markussen G, Kvale D, Brandtzaeg P, Thorsby E (1987)
Induction of various HLA class II molecules in a human colonic adenocarcinoma cell line
Scand J Immunol, 25 (2), 175-80
DOI 10.1111/j.1365-3083.1987.tb01061.x, PubMed 2434988

Sollid LM, Kvale D, Brandtzaeg P, Markussen G, Thorsby E (1987)
Interferon-gamma enhances expression of secretory component, the epithelial receptor for polymeric immunoglobulins
J Immunol, 138 (12), 4303-6
PubMed 3108385

Sollid LM, Kvale D, Brandtzaeg P, Markussen G, Thorsby E (1987)
Synthesis of cytoplasmic and functional membrane SC induced by gamma-interferon
Adv Exp Med Biol, 216B, 1109-16
PubMed 3122531

Thrane PS, Sollid LM, Huitfeldt H, Brandtzaeg P (1987)
Pleomorphic adenomas contain a keratin-negative population of HLA-DR-positive dendritic cells
Adv Exp Med Biol, 216A, 437-44
DOI 10.1007/978-1-4684-5344-7_51, PubMed 2446470

Publications 1986

Bruserud O, Sollid L, Gaudernack G, Thorsby E (1986)
The role of the CD8-positive subset of T cells in proliferative responses to soluble antigens. II. CD8-positive cells are not responsible for DR-associated differences in responsiveness to mumps and Coxsackie B4
Scand J Immunol, 23 (4), 469-73
PubMed 3010444

Bruserud O, Sollid L, Jørgensen PF (1986)
The proliferative T-lymphocyte response to streptokinase
J Clin Lab Immunol, 20 (2), 69-74
PubMed 2942694

Sollid L, Bruserud O, Gaudernack G, Thorsby E (1986)
The role of the CD8-positive subset of T cells in proliferative responses to soluble antigens. I. Studies of healthy subjects, type 1 diabetics, and coeliac disease patients
Scand J Immunol, 23 (4), 461-7
DOI 10.1111/j.1365-3083.1986.tb03077.x, PubMed 3010443

Sollid LM, Kolberg J, Scott H, Ek J, Fausa O, Brandtzaeg P (1986)
Antibodies to wheat germ agglutinin in coeliac disease
Clin Exp Immunol, 63 (1), 95-100
PubMed 3754186

Sollid LM, Scott H, Kolberg J, Brandtzaeg P (1986)
Serum antibodies to wheat germ agglutinin and gluten in patients with dermatitis herpetiformis
Arch Dermatol Res, 278 (6), 433-6
DOI 10.1007/BF00455158, PubMed 3789802

Publications 1985

Kolberg J, Sollid L (1985)
Lectin activity of gluten identified as wheat germ agglutinin
Biochem Biophys Res Commun, 130 (2), 867-72
DOI 10.1016/0006-291x(85)90496-6, PubMed 3839672

SOLLID L, SCOTT H, THORSBY E (1985)
SUPPRESSOR-CELL ACTIVITY IN CELIAC-DISEASE
Lancet, 1 (8422), 229

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