Publications Pancreatic Cancer Research Group

Publications 2024

Amrutkar M, Guttorm SJT, Finstadsveen AV, Labori KJ, Eide L, Rootwelt H, Elgstøen KBP, Gladhaug IP, Verbeke CS (2024)
Global metabolomic profiling of tumor tissue and paired serum samples to identify biomarkers for response to neoadjuvant FOLFIRINOX treatment of human pancreatic cancer
Mol Oncol (in press)
DOI 10.1002/1878-0261.13759, PubMed 39545923

Anandavadivelan P, Cardinale D, Blomhoff R, Sunde B, Lassen K, Kleive D, Sturesson C, Gilg S, Raastad T, Mijwel S (2024)
Blood flow restriction Exercise in the perioperative setting to Prevent loss of muscle mass in patients with pancreatic, biliary tract, and liver cancer: study protocol for the PREV-Ex randomized controlled trial
Trials, 25 (1), 356
DOI 10.1186/s13063-024-08207-5, PubMed 38835083

Ansari D, Søreide K, Andersson B, Hansen CP, Seppänen H, Sparrelid E, Labori KJ, Kirkegård J, Kauhanen S, Månsson C, Nymo LS, Nortunen M, Björnsson B, Kivivuori A, Tingstedt B, Bratlie SO, Waardal K, Laukkarinen J, Halimi A, Lindberg H, Olin H, Andersson R, Nordic Pancreatic Cancer Network (2024)
Surveillance after surgery for pancreatic cancer: a global scoping review of guidelines and a nordic Survey of contemporary practice
Scand J Gastroenterol, 59 (9), 1097-1104
DOI 10.1080/00365521.2024.2378948, PubMed 38994854

Bruna CL, van Hilst J, Esposito A, Kleive D, Falconi M, Primrose JN, Korrel M, Bianchi D, Zerbi A, Kokkola A, Butturini G, Björnsson B, Morone M, Casadei R, Marudanayagam R, Besselink MG, Abu Hilal M, European Consortium on Minimally Invasive Pancreatic Surgery (E-MIPS) (2024)
The value of splenectomy during left-sided pancreatectomy for pancreatic ductal adenocarcinoma: predefined subanalysis in the DIPLOMA randomized trial
Br J Surg, 111 (9)
DOI 10.1093/bjs/znae236, PubMed 39287489

Coppola A, La Vaccara V, Farolfi T, Asbun HJ, Boggi U, Conlon K, Edwin B, Ferrone C, Jonas E, Kokudo N, Perez EM, Satoi S, Sparrelid E, Stauffer J, Zerbi A, Takemura N, Lai Q, Almerey T, Bernon M, Cammarata R, Djoumi Y, Gallagher T, Ghorbani P, Ginesini M, Hashimoto D et al. (2024)
Preoperative carbohydrate antigen 19.9 level predicts lymph node metastasis in resectable adenocarcinoma of the head of the pancreas: a further plea for biological resectability criteria
Int J Surg, 110 (10), 6092-6099
DOI 10.1097/JS9.0000000000000773, PubMed 37738016

Farnes I, Lund-Iversen M, Aabakken L, Verbeke C, Labori KJ (2024)
Molecular testing for personalized therapy is underutilized in patients with borderline resectable and locally advanced pancreatic cancer - real world data from the NORPACT-2 study
Scand J Gastroenterol, 59 (9), 1093-1096
DOI 10.1080/00365521.2024.2373115, PubMed 38957079

Kjeseth T, Hagen RE, Edwin B, Lai X, Røsok BI, Tholfsen T, Sahakyan MA, Kleive D (2024)
Impact of pancreas transection site on incidence of pancreatic fistula after distal pancreatectomy: a propensity score matched study
HPB (Oxford), 26 (9), 1164-1171
DOI 10.1016/j.hpb.2024.05.012, PubMed 38839509

Labori KJ, Bratlie SO, Andersson B, Angelsen JH, Biörserud C, Björnsson B, Bringeland EA, Elander N, Garresori H, Grønbech JE, Haux J, Hemmingsson O, Liljefors MG, Myklebust TÅ, Nymo LS, Peltola K, Pfeiffer P, Sallinen V, Sandström P, Sparrelid E, Stenvold H, Søreide K, Tingstedt B, Verbeke C, Öhlund D et al. (2024)
Neoadjuvant FOLFIRINOX versus upfront surgery for resectable pancreatic head cancer (NORPACT-1): a multicentre, randomised, phase 2 trial
Lancet Gastroenterol Hepatol, 9 (3), 205-217
DOI 10.1016/S2468-1253(23)00405-3, PubMed 38237621

Labori KJ, Bratlie SO, Dueland S, Lassen K (2024)
NORPACT-1: implications for future trials - Authors' reply
Lancet Gastroenterol Hepatol, 9 (5), 408-409
DOI 10.1016/S2468-1253(24)00079-7, PubMed 38604194

Perri G, Romandini E, Marchegiani G, Ghorbani P, Sahakyan M, Holmberg M, Cattelani A, Fretland Å, Montorsi R, Rodrigues ID, Kleive D, Bannone E, Edwin B, Gilg S, Labori K, Sparrelid E, Salvia R (2024)
Postoperative Hyperamylasemia (POH) is an Early Predictor of Pancreatic Fistula Occurrence and Severity after Distal Pancreatectomy: Results from a European Multicentric Study
Ann Surg (in press)
DOI 10.1097/SLA.0000000000006222, PubMed 38305035

Stoop TF, Oba A, Wu YHA, Beaty LE, Colborn KL, Janssen BV, Al-Musawi MH, Franco SR, Sugawara T, Franklin O, Jain A, Saiura A, Sauvanet A, Coppola A, Javed AA, Groot Koerkamp B, Miller BN, Mack CE, Hashimoto D, Caputo D, Kleive D, Sereni E, Belfiori G, Ichida H, van Dam JL et al. (2024)
Pathological Complete Response in Patients With Resected Pancreatic Adenocarcinoma After Preoperative Chemotherapy
JAMA Netw Open, 7 (6), e2417625
DOI 10.1001/jamanetworkopen.2024.17625, PubMed 38888920

van Bodegraven EA, van Ramshorst TME, Bratlie SO, Kokkola A, Sparrelid E, Björnsson B, Kleive D, Burgdorf SK, Dokmak S, Groot Koerkamp B, Cabús SS, Molenaar IQ, Boggi U, Busch OR, Petrič M, Roeyen G, Hackert T, Lips DJ, D'Hondt M, Coolsen MME, Ferrari G, Tingstedt B, Serrablo A, Gaujoux S, Ramera M et al. (2024)
Minimally invasive robot-assisted and laparoscopic distal pancreatectomy in a pan-European registry a retrospective cohort study
Int J Surg, 110 (6), 3554-3561
DOI 10.1097/JS9.0000000000001315, PubMed 38498397

van Ramshorst TME, van Hilst J, Boggi U, Dokmak S, Edwin B, Keck T, Khatkov I, Balduzzi A, Pulvirenti A, Ahmad J, Al Saati H, Alseidi A, Ausania F, Azagra JS, Balzano G, Björnsson B, Can FM, Cillo U, D'Hondt M, Efanov M, Erkan M, Espin Alvarez F, Esposito A, Ferrari G, Groot Koerkamp B et al. (2024)
Standardizing definitions and terminology of left-sided pancreatic resections through an international Delphi consensus
Br J Surg, 111 (4)
DOI 10.1093/bjs/znae039, PubMed 38686655

Waage A, Khan A, Labori KJ, Birkeland KI, Scholz H, Jensen TG, Tholfsen T, Line PD, Hagness M (2024)
Implementation of a nationwide program for total pancreatectomy and islet autotransplantation in chronic pancreatitis: A Scandinavian single-center observational study
Scand J Surg, 14574969241298985 (in press)
DOI 10.1177/14574969241298985, PubMed 39558154

Yadeta DA, Manyazewal T, Demessie DB, Kleive D (2024)
Incidence and predictors of postoperative complications in Sub-Saharan Africa: a systematic review and meta-analysis
Front Health Serv, 4, 1353788
DOI 10.3389/frhs.2024.1353788, PubMed 38784705

Yaqub S, Røsok B, Gladhaug IP, Labori KJ (2024)
Pancreatic duct occlusion with polychloroprene-based glue for the management of postoperative pancreatic fistula after pancreatoduodenectomy-an outdated approach?
Front Surg, 11, 1386708
DOI 10.3389/fsurg.2024.1386708, PubMed 38645504

Publications 2023

Amrutkar M, Berg K, Balto A, Skilbrei MG, Finstadsveen AV, Aasrum M, Gladhaug IP, Verbeke CS (2023)
Pancreatic stellate cell-induced gemcitabine resistance in pancreatic cancer is associated with LDHA- and MCT4-mediated enhanced glycolysis
Cancer Cell Int, 23 (1), 9
DOI 10.1186/s12935-023-02852-7, PubMed 36658582

Farnes I, Kleive D, Verbeke CS, Aabakken L, Issa-Epe A, Småstuen MC, Fosby BV, Dueland S, Line PD, Labori KJ (2023)
Resection rates and intention-to-treat outcomes in borderline and locally advanced pancreatic cancer: real-world data from a population-based, prospective cohort study (NORPACT-2)
BJS Open, 7 (6)
DOI 10.1093/bjsopen/zrad137, PubMed 38155512

Farnes I, Paulsen V, Verbeke CS, Tønnesen CJ, Aabakken L, Labori KJ (2023)
Performance and safety of diagnostic EUS FNA/FNB and therapeutic ERCP in patients with borderline resectable and locally advanced pancreatic cancer - results from a population-based, prospective cohort study
Scand J Gastroenterol, 59 (4), 496-502
DOI 10.1080/00365521.2023.2290456, PubMed 38126766

Khan A, Fosby B, Labori KJ, Lanari J, Dorenberg E, Line PD (2023)
Management of Coeliac and Hepatic Artery Aneurysms: An Experience of 84 Cases
Eur J Vasc Endovasc Surg, 66 (6), 814-820
DOI 10.1016/j.ejvs.2023.09.032, PubMed 37722651

Kjeseth T, Yaqub S, Edwin B, Kleive D, Sahakyan MA (2023)
Peri-firing compression in prevention of pancreatic fistula after distal pancreatectomy: A systematic review and a cohort study
Scand J Surg, 113 (2), 73-79
DOI 10.1177/14574969231211084, PubMed 37982224

Kleive D, Yaqub S, Søreide K (2023)
Is there a survival benefit of a robotic approach to pancreatoduodenectomy for pancreatic cancer?
Hepatobiliary Surg Nutr, 12 (1), 92-94
DOI 10.21037/hbsn-22-500, PubMed 36860241

Li Y, Amrutkar M, Finstadsveen AV, Dalen KT, Verbeke CS, Gladhaug IP (2023)
Fatty acids abrogate the growth-suppressive effects induced by inhibition of cholesterol flux in pancreatic cancer cells
Cancer Cell Int, 23 (1), 276
DOI 10.1186/s12935-023-03138-8, PubMed 37978383

Sahakyan MA, Kleive D, Dille-Amdam RG, Kjeseth T, Waardal K, Edwin B, Nymo LS, Lassen K (2023)
The Role of Preoperative Inflammatory Markers in Pancreatectomy: a Norwegian Nationwide Cohort Study
J Gastrointest Surg, 27 (8), 1650-1659
DOI 10.1007/s11605-023-05726-5, PubMed 37322265

van Dam JL, Verkolf EMM, Dekker EN, Bonsing BA, Bratlie SO, Brosens LAA, Busch OR, van Driel LMJW, van Eijck CHJ, Feshtali S, Ghorbani P, de Groot DJA, de Groot JWB, Haberkorn BCM, de Hingh IH, van der Holt B, Karsten TM, van der Kolk MB, Labori KJ, Liem MSL, Loosveld OJL, Molenaar IQ, Polée MB, van Santvoort HC, de Vos-Geelen J et al. (2023)
Perioperative or adjuvant mFOLFIRINOX for resectable pancreatic cancer (PREOPANC-3): study protocol for a multicenter randomized controlled trial
BMC Cancer, 23 (1), 728
DOI 10.1186/s12885-023-11141-5, PubMed 37550634

Yaqub S, Tholfsen T, Waage A, Kleive D, Labori KJ (2023)
Pancreatoduodenectomy after Roux-en-Y gastric bypass surgery: Single-center experience and literature review
Scand J Surg, 112 (2), 98-104
DOI 10.1177/14574969231156350, PubMed 36803183

Publications 2022

Amrutkar M, Verbeke CS, Finstadsveen AV, Dorg L, Labori KJ, Gladhaug IP (2022)
Neoadjuvant chemotherapy is associated with an altered metabolic profile and increased cancer stemness in patients with pancreatic ductal adenocarcinoma
Mol Oncol, 17 (1), 59-81
DOI 10.1002/1878-0261.13344, PubMed 36400567

Ghotbi J, Sahakyan M, Søreide K, Fretland ÅA, Røsok B, Tholfsen T, Waage A, Edwin B, Labori KJ, Yaqub S, Kleive D (2022)
Minimally Invasive Pancreatoduodenectomy: Contemporary Practice, Evidence, and Knowledge Gaps
Oncol Ther, 10 (2), 301-315
DOI 10.1007/s40487-022-00203-6, PubMed 35829933

Giani A, van Ramshorst T, Mazzola M, Bassi C, Esposito A, de Pastena M, Edwin B, Sahakyan M, Kleive D, Jah A, van Laarhoven S, Boggi U, Kauffman EF, Casadei R, Ricci C, Dokmak S, Ftériche FS, White SA, Kamarajah SK, Butturini G, Frigerio I, Zerbi A, Capretti G, Pando E, Sutcliffe RP et al. (2022)
Benchmarking of minimally invasive distal pancreatectomy with splenectomy: European multicentre study
Br J Surg, 109 (11), 1124-1130
DOI 10.1093/bjs/znac204, PubMed 35834788

Krogvold L, Genoni A, Puggioni A, Campani D, Richardson SJ, Flaxman CS, Edwin B, Buanes T, Dahl-Jørgensen K, Toniolo A (2022)
Live enteroviruses, but not other viruses, detected in human pancreas at the onset of type 1 diabetes in the DiViD study
Diabetologia, 65 (12), 2108-2120
DOI 10.1007/s00125-022-05779-2, PubMed 35953727

Labori KJ (2022)
Short-Course or Total Neoadjuvant Chemotherapy in Resectable and Borderline Resectable Pancreatic Cancer - Current Status and Future Perspectives
Front Surg, 9, 839339
DOI 10.3389/fsurg.2022.839339, PubMed 35548190

Silwal-Pandit L, Stålberg SM, Henrik J. Johansson, Georgios Mermelekas, Lothe IMB, Skrede ML, Dalsgaard AM, Nebdal D, Helland, Lingjærde OC, Labori KJ, Skålhegg BS, Janne Lehtiö, Kure EH (2022)
Proteome Analysis of Pancreatic Tumors Implicates Extracellular Matrix in Patient Outcome
Cancer Res Commun, 2 (6), 434-446
DOI 10.1158/2767-9764.CRC-21-0100, PublikaID 411

Silwal-Pandit L, Stålberg SM, Johansson HJ, Mermelekas G, Lothe IMB, Skrede ML, Dalsgaard AM, Nebdal DJH, Helland Å, Lingjærde OC, Labori KJ, Skålhegg BS, Lehtiö J, Kure EH (2022)
Proteome Analysis of Pancreatic Tumors Implicates Extracellular Matrix in Patient Outcome
Cancer Res Commun, 2 (6), 434-446
DOI 10.1158/2767-9764.CRC-21-0100, PubMed 36923555

van Veldhuisen E, Klompmaker S, Janssen QP, Hilal MA, Alseidi A, Balduzzi A, Balzano G, Bassi C, Berrevoet F, Bonds M, Busch OR, Butturini G, Conlon KC, Frigerio IM, Fusai GK, Gagnière J, Griffin O, Hackert T, Halimi A, Keck T, Kleeff J, Klaiber U, Labori KJ, Lesurtel M, Malleo G et al. (2022)
Surgical and Oncological Outcomes After Preoperative FOLFIRINOX Chemotherapy in Resected Pancreatic Cancer: An International Multicenter Cohort Study
Ann Surg Oncol, 30 (3), 1463-1473
DOI 10.1245/s10434-022-12387-2, PubMed 36539580

Waage A, Vinge-Holmquist O, Labori KJ, Paulsen V, Aabakken L, Lenz H, Felix Magnus HC, Tholfsen T, Hauge T (2022)
Tailored surgery in chronic pancreatitis after implementation of a multidisciplinary team assessment; a prospective observational study
HPB (Oxford), 24 (12), 2157-2166
DOI 10.1016/j.hpb.2022.09.007, PubMed 36272955

Yaqub S, Jensenius M, Heieren OE, Drolsum A, Pettersen FO, Labori KJ (2022)
Echinococcosis in a non-endemic country - 20-years' surgical experience from a Norwegian tertiary referral Centre
Scand J Gastroenterol, 57 (8), 953-957
DOI 10.1080/00365521.2022.2046846, PubMed 35246008

Publications 2021

Amrutkar M, Gladhaug IP (2021)
Stellate Cells Aid Growth-Permissive Metabolic Reprogramming and Promote Gemcitabine Chemoresistance in Pancreatic Cancer
Cancers (Basel), 13 (4)
DOI 10.3390/cancers13040601, PubMed 33546284

Fosheim IK, Lappen KR, Heldal K, Mariathasan AB, Lundesgaard KK, Benterud BP, Pettersen FO, Labori KJ, Yaqub S (2021)
[A young woman who did not awake after extensive surgery]
Tidsskr Nor Laegeforen, 141
DOI 10.4045/tidsskr.21.0184, PubMed 34726048

Fosheim IK, Lappen KR, Heldal K, Mariathasan AB, Lundesgaard KK, Pettersen FO, Labori KJ, Yaqub S, Benterud BP (2021)
A young woman who did not wake up after extensive surgery
Tidsskr. Nor. Laegeforen., 141 (15), 1456-1461

Grut H, Line PD, Labori KJ, Schulz A, Dueland S (2021)
Survival after liver resection and liver transplantation for colorectal liver metastases: a comparative analysis stratified by metabolic tumor volume assessed by ¹⁸F-FDG PET/CT
HPB (Oxford), 24 (7), 1055-1062
DOI 10.1016/j.hpb.2021.11.015, PubMed 34924292

Hugenschmidt H, Labori KJ, Borgen E, Brunborg C, Schirmer CB, Seeberg LT, Naume B, Wiedswang G (2021)
Preoperative CTC-Detection by CellSearch^® Is Associated with Early Distant Metastasis and Impaired Survival in Resected Pancreatic Cancer
Cancers (Basel), 13 (3)
DOI 10.3390/cancers13030485, PubMed 33513877

Kleive D, Aas E, Angelsen JH, Bringeland EA, Nesbakken A, Nymo LS, Schultz JK, Søreide K, Yaqub S (2021)
Simultaneous Resection of Primary Colorectal Cancer and Synchronous Liver Metastases: Contemporary Practice, Evidence and Knowledge Gaps
Oncol Ther, 9 (1), 111-120
DOI 10.1007/s40487-021-00148-2, PubMed 33759076

Labori KJ, Tholfsen T, Yaqub S, Lassen K, Kleive D, Waage A (2021)
Gastro- or Duodenojejunostomy Leaks After Pancreatoduodenectomy: Single Center Experience and Narrative Literature Review
J Gastrointest Surg, 25 (12), 3130-3136
DOI 10.1007/s11605-021-05058-2, PubMed 34131862

Lindholm E, Bergmann GB, Haugaa H, Labori KJ, Yaqub S, Bjørnbeth BA, Line PD, Grindheim G, Kjøsen G, Pischke SE, Tønnessen TI (2021)
Early detection of anastomotic leakage after pancreatoduodenectomy with microdialysis catheters: an observational Study
HPB (Oxford), 24 (6), 901-909
DOI 10.1016/j.hpb.2021.10.020, PubMed 34836755

Oikarinen S, Krogvold L, Edwin B, Buanes T, Korsgren O, Laiho JE, Oikarinen M, Ludvigsson J, Skog O, Anagandula M, Frisk G, Hyöty H, Dahl-Jørgensen K (2021)
Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study
Diabetologia, 64 (11), 2491-2501
DOI 10.1007/s00125-021-05525-0, PubMed 34390364

Sahakyan MA, Labori KJ, Edwin B (2021)
ASO Author Reflections: Resection Margins in Distal Pancreatectomy for Ductal Adenocarcinoma-Does Surgery Tell the Whole Story?
Ann Surg Oncol, 29 (1), 376-377
DOI 10.1245/s10434-021-10515-y, PubMed 34304314

Sahakyan MA, Røsok BI, Tholfsen T, Kleive D, Waage A, Ignjatovic D, Buanes T, Labori KJ, Edwin B (2021)
Implementation and training with laparoscopic distal pancreatectomy: 23-year experience from a high-volume center
Surg Endosc, 36 (1), 468-479
DOI 10.1007/s00464-021-08306-3, PubMed 33534075

Sahakyan MA, Verbeke CS, Tholfsen T, Ignjatovic D, Kleive D, Buanes T, Lassen K, Rosok BI, Labori KJ, Edwin B (2021)
ASO Visual Abstract: Prognostic Impact of Resection Margin Status in Distal Pancreatectomy for Ductal Adenocarcinoma
Ann. Surg. Oncol., 28 (SUPPL 3 3), 570
DOI 10.1245/s10434-021-10531-y

Sahakyan MA, Verbeke CS, Tholfsen T, Ignjatovic D, Kleive D, Buanes T, Lassen K, Røsok BI, Labori KJ, Edwin B (2021)
Prognostic Impact of Resection Margin Status in Distal Pancreatectomy for Ductal Adenocarcinoma
Ann Surg Oncol, 29 (1), 366-375
DOI 10.1245/s10434-021-10464-6, PubMed 34296358

Sántha P, Lenggenhager D, Finstadsveen A, Dorg L, Tøndel K, Amrutkar M, Gladhaug IP, Verbeke C (2021)
Morphological Heterogeneity in Pancreatic Cancer Reflects Structural and Functional Divergence
Cancers (Basel), 13 (4)
DOI 10.3390/cancers13040895, PubMed 33672734

Publications 2020

Amrutkar M, Larsen EK, Aasrum M, Finstadsveen AV, Andresen PA, Verbeke CS, Gladhaug IP (2020)
Establishment and Characterization of Paired Primary Cultures of Human Pancreatic Cancer Cells and Stellate Cells Derived from the Same Tumor
Cells, 9 (1)
DOI 10.3390/cells9010227, PubMed 31963309

Amrutkar M, Vethe NT, Verbeke CS, Aasrum M, Finstadsveen AV, Sántha P, Gladhaug IP (2020)
Differential Gemcitabine Sensitivity in Primary Human Pancreatic Cancer Cells and Paired Stellate Cells Is Driven by Heterogenous Drug Uptake and Processing
Cancers (Basel), 12 (12)
DOI 10.3390/cancers12123628, PubMed 33287390

Berg JP, Gladhaug IP (2020)
[The thesis defence is part of the doctoral degree examination]
Tidsskr Nor Laegeforen, 140 (9)
DOI 10.4045/tidsskr.20.0328, PubMed 32549008

Berg JP, Gladhaug IP (2020)
The Thesis is part of the doctoral degree
Tidsskr. Nor. Laegeforen., 140 (9), 866-867

Engebretsen E, Gladhaug IP (2020)
Is there room for a nursing science community in a medical faculty?
Tidsskr Nor Laegeforen, 140 (9)
DOI 10.4045/tidsskr.20.0311, PubMed 32549028

Engebretsen E, Gladhaug IP (2020)
Is there room for a nursing science professional environment at a medical faculty?
Tidsskr. Nor. Laegeforen., 140 (9), 862-863

Grut H, Stern NM, Dueland S, Labori KJ, Dormagen JB, Schulz A (2020)
Preoperative 18F-FDG PET/computed tomography predicts survival following resection for colorectal liver metastases
Nucl Med Commun, 41 (9), 916-923
DOI 10.1097/MNM.0000000000001235, PubMed 32796480

Hugenschmidt H, Labori KJ, Brunborg C, Verbeke CS, Seeberg LT, Bendigtsen Schirmer C, Renolen A, Borgen E, Naume B, Wiedswang G (2020)
Cytokeratin-positive cells in the bone marrow from patients with pancreatic, periampullary malignancy and benign pancreatic disease show no prognostic information
BMC Cancer, 20 (1), 1107
DOI 10.1186/s12885-020-07510-z, PubMed 33198661

Hugenschmidt H, Labori KJ, Brunborg C, Verbeke CS, Seeberg LT, Schirmer CB, Renolen A, Borgen EF, Naume B, Wiedswang G (2020)
Circulating Tumor Cells are an Independent Predictor of Shorter Survival in Patients Undergoing Resection for Pancreatic and Periampullary Adenocarcinoma
Ann Surg, 271 (3), 549-558
DOI 10.1097/SLA.0000000000003035, PubMed 30216219

Khan A, Kleive D, Aandahl EM, Fosby B, Line PD, Dorenberg E, Guvåg S, Labori KJ (2020)
Portal vein stent placement after hepatobiliary and pancreatic surgery
Langenbecks Arch Surg, 405 (5), 657-664
DOI 10.1007/s00423-020-01917-9, PubMed 32621087

Labori KJ, Kleive D, Khan A, Farnes I, Fosby B, Line PD (2020)
Graft type for superior mesenteric and portal vein reconstruction in pancreatic surgery - A systematic review
HPB (Oxford), 23 (4), 483-494
DOI 10.1016/j.hpb.2020.11.008, PubMed 33288403

Latenstein AEJ, Scholten L, Al-Saffar HA, Björnsson B, Butturini G, Capretti G, Chatzizacharias NA, Dervenis C, Frigerio I, Gallagher TK, Gasteiger S, Halimi A, Labori KJ, Montagnini G, Muñoz-Bellvis L, Nappo G, Nikov A, Pando E, Pastena M, Peña-Moral JM, Radenkovic D, Roberts KJ, Salvia R, Sanchez-Bueno F, Scandavini C et al. (2020)
Clinical Outcomes After Total Pancreatectomy: A Prospective Multicenter Pan-European Snapshot Study
Ann Surg, 276 (5), e536-e543
DOI 10.1097/SLA.0000000000004551, PubMed 33177356

Nymo LS, Kleive D, Waardal K, Bringeland EA, Søreide JA, Labori KJ, Mortensen KE, Søreide K, Lassen K (2020)
Centralizing a national pancreatoduodenectomy service: striking the right balance
BJS Open, 4 (5), 904-913
DOI 10.1002/bjs5.50342, PubMed 32893988

Sahakyan MA, Tholfsen T, Kleive D, Waage A, Buanes T, Labori KJ, Røsok BI, Edwin B (2020)
Laparoscopic distal pancreatectomy in patients with poor physical status
HPB (Oxford), 23 (6), 877-881
DOI 10.1016/j.hpb.2020.10.004, PubMed 33092964

Sahakyan MA, Tholfsen T, Kleive D, Yaqub S, Kazaryan AM, Buanes T, Røsok BI, Labori KJ, Edwin B (2020)
Laparoscopic Distal Pancreatectomy Following Prior Upper Abdominal Surgery (Pancreatectomy and Prior Surgery)
J Gastrointest Surg, 25 (7), 1787-1794
DOI 10.1007/s11605-020-04858-2, PubMed 33170476

van Roessel S, van Veldhuisen E, Klompmaker S, Janssen QP, Abu Hilal M, Alseidi A, Balduzzi A, Balzano G, Bassi C, Berrevoet F, Bonds M, Busch OR, Butturini G, Del Chiaro M, Conlon KC, Falconi M, Frigerio I, Fusai GK, Gagnière J, Griffin O, Hackert T, Halimi A, Klaiber U, Labori KJ, Malleo G et al. (2020)
Evaluation of Adjuvant Chemotherapy in Patients With Resected Pancreatic Cancer After Neoadjuvant FOLFIRINOX Treatment
JAMA Oncol, 6 (11), 1733-1740
DOI 10.1001/jamaoncol.2020.3537, PubMed 32910170

Publications 2019

Amrutkar M, Aasrum M, Verbeke CS, Gladhaug IP (2019)
Secretion of fibronectin by human pancreatic stellate cells promotes chemoresistance to gemcitabine in pancreatic cancer cells
BMC Cancer, 19 (1), 596
DOI 10.1186/s12885-019-5803-1, PubMed 31208372

Berg JP, Gladhaug IP (2019)
[It is essential to fulfil the purpose of the trial lecture]
Tidsskr Nor Laegeforen, 139 (16)
DOI 10.4045/tidsskr.19.0646, PubMed 31686487

Berg JP, Gladhaug IP (2019)
It is important that the purpose of the trial lecture is fulfilled
Tidsskr. Nor. Laegeforen., 139 (16), 1534

Bowitz Lothe IM, Kleive D, Pomianowska E, Cvancarova M, Kure E, Dueland S, Gladhaug IP, Labori KJ (2019)
Clinical relevance of pancreatobiliary and intestinal subtypes of ampullary and duodenal adenocarcinoma: Pattern of recurrence, chemotherapy, and survival after pancreatoduodenectomy
Pancreatology, 19 (2), 316-324
DOI 10.1016/j.pan.2019.01.019, PubMed 30713128

Heiberg T, Baekelandt B, Kvien TK, Buanes T (2019)
Psychometric performance of the PAncreatic CAncer disease impact (PACADI) score
Pancreatology, 19 (7), 971-978
DOI 10.1016/j.pan.2019.09.001, PubMed 31530448

Kleive D, Labori KJ, Line PD, Gladhaug IP, Verbeke CS (2019)
Pancreatoduodenectomy with venous resection for ductal adenocarcinoma rarely achieves complete (R0) resection
HPB (Oxford), 22 (1), 50-57
DOI 10.1016/j.hpb.2019.05.005, PubMed 31186199

Kleive D, Sahakyan MA, Labori KJ, Lassen K (2019)
Nasogastric Tube on Demand is Rarely Necessary After Pancreatoduodenectomy Within an Enhanced Recovery Pathway
World J Surg, 43 (10), 2616-2622
DOI 10.1007/s00268-019-05045-4, PubMed 31161355

Lenggenhager D, Amrutkar M, Sántha P, Aasrum M, Löhr JM, Gladhaug IP, Verbeke CS (2019)
Commonly Used Pancreatic Stellate Cell Cultures Differ Phenotypically and in Their Interactions with Pancreatic Cancer Cells
Cells, 8 (1)
DOI 10.3390/cells8010023, PubMed 30621293

Sahakyan MA, Labori KJ, Primavesi F, Soreide K, Stattner S, Edwin B (2019)
Minimally invasive pancreatic surgerywhere are we going?
Eur. Surg., 51 (3), 98-104
DOI 10.1007/s10353-019-0576-y

Sandhu V, Labori KJ, Borgida A, Lungu I, Bartlett J, Hafezi-Bakhtiari S, Denroche RE, Jang GH, Pasternack D, Mbaabali F, Watson M, Wilson J, Kure EH, Gallinger S, Haibe-Kains B (2019)
Meta-Analysis of 1,200 Transcriptomic Profiles Identifies a Prognostic Model for Pancreatic Ductal Adenocarcinoma
JCO Clin Cancer Inform, 3, 1-16
DOI 10.1200/CCI.18.00102, PubMed 31070984

Soreide K, Primavesi F, Labori KJ, Watson MM, Stattner S (2019)
Molecular biology in pancreatic ductal adenocarcinoma: implications for future diagnostics and therapy
Eur. Surg., 51 (3), 126-134
DOI 10.1007/s10353-019-0575-z

Søreide K, Nymo LS, Kleive D, Olsen F, Lassen K (2019)
Variation in use of open and laparoscopic distal pancreatectomy and associated outcome metrics in a universal health care system
Pancreatology, 19 (6), 880-887
DOI 10.1016/j.pan.2019.07.047, PubMed 31395453

Thorsen T, Solheim JM, Labori KJ, Line PD, Aandahl EM (2019)
Liver transplantation as a lifesaving procedure for posthepatectomy liver failure and iatrogenic liver injuries
Langenbecks Arch Surg, 404 (3), 301-308
DOI 10.1007/s00423-019-01780-3, PubMed 30929063

Ånonsen K, Sahakyan MA, Kleive D, Waage A, Verbeke C, Hauge T, Buanes T, Edwin B, Labori KJ (2019)
Trends in management and outcome of cystic pancreatic lesions - analysis of 322 cases undergoing surgical resection
Scand J Gastroenterol, 54 (8), 1051-1057
DOI 10.1080/00365521.2019.1642379, PubMed 31322457

Publications 2018

Baekelandt BMG, Fagerland MW, Hjermstad MJ, Heiberg T, Labori KJ, Buanes TA (2018)
Survival, Complications and Patient Reported Outcomes after Pancreatic Surgery
HPB (Oxford), 21 (3), 275-282
DOI 10.1016/j.hpb.2018.07.023, PubMed 30120002

Brudvik KW, Røsok B, Naresh U, Yaqub S, Fretland ÅA, Labori KJ, Edwin B, Bjørnbeth BA (2018)
Survival after resection of colorectal liver metastases in octogenarians and sexagenarians compared to their respective age-matched national population
Hepatobiliary Surg Nutr, 7 (4), 234-241
DOI 10.21037/hbsn.2017.09.03, PubMed 30221151

Buanes T, Edwin B (2018)
Long term oncological outcome of laparoscopic techniques in pancreatic cancer
World J Gastrointest Endosc, 10 (12), 383-391
DOI 10.4253/wjge.v10.i12.383, PubMed 30631402

Kleive D, Sahakyan M, Søreide K, Brudvik KW, Line PD, Gladhaug IP, Labori KJ (2018)
Risk for hemorrhage after pancreatoduodenectomy with venous resection
Langenbecks Arch Surg, 403 (8), 949-957
DOI 10.1007/s00423-018-1721-y, PubMed 30397778

Kleive D, Sahakyan MA, Khan A, Fosby B, Line PD, Labori KJ (2018)
Incidence and management of arterial injuries during pancreatectomy
Langenbecks Arch Surg, 403 (3), 341-348
DOI 10.1007/s00423-018-1666-1, PubMed 29564544

Klompmaker S, van Hilst J, Gerritsen SL, Adham M, Teresa Albiol Quer M, Bassi C, Berrevoet F, Boggi U, Busch OR, Cesaretti M, Dalla Valle R, Darnis B, De Pastena M, Del Chiaro M, Grützmann R, Diener MK, Dumitrascu T, Friess H, Ivanecz A, Karayiannakis A, Fusai GK, Labori KJ, Lombardo C, López-Ben S, Mabrut JY et al. (2018)
Outcomes After Distal Pancreatectomy with Celiac Axis Resection for Pancreatic Cancer: A Pan-European Retrospective Cohort Study
Ann Surg Oncol, 25 (5), 1440-1447
DOI 10.1245/s10434-018-6391-z, PubMed 29532342

Klompmaker S, van Hilst J, Gerritsen SL, Adham M, Teresa Albiol Quer M, Bassi C, Berrevoet F, Boggi U, Busch OR, Cesaretti M, Dalla Valle R, Darnis B, De Pastena M, Del Chiaro M, Grützmann R, Diener MK, Dumitrascu T, Friess H, Ivanecz A, Karayiannakis A, Fusai GK, Labori KJ, Lombardo C, López-Ben S, Mabrut JY et al. (2018)
Correction to: Outcomes After Distal Pancreatectomy with Celiac Axis Resection for Pancreatic Cancer: A Pan-European Retrospective Cohort Study
Ann Surg Oncol, 25 (Suppl 3), 988
DOI 10.1245/s10434-018-6442-5, PubMed 29560574

Nymo LS, Søreide K, Kleive D, Olsen F, Lassen K (2018)
The effect of centralization on short term outcomes of pancreatoduodenectomy in a universal health care system
HPB (Oxford), 21 (3), 319-327
DOI 10.1016/j.hpb.2018.08.011, PubMed 30297306

Sahakyan MA, Kleive D, Kazaryan AM, Aghayan DL, Ignjatovic D, Labori KJ, Røsok BI, Edwin B (2018)
Extended laparoscopic distal pancreatectomy for adenocarcinoma in the body and tail of the pancreas: a single-center experience
Langenbecks Arch Surg, 403 (8), 941-948
DOI 10.1007/s00423-018-1730-x, PubMed 30417281

Sahakyan MA, Røsok BI, Kleive D, Fretland ÅA, Kazaryan AM, Labori KJ, Edwin B (2018)
The European Experience in Laparoscopic Pancreatic Resections
J Am Coll Surg, 226 (1), 104
DOI 10.1016/j.jamcollsurg.2017.10.003, PubMed 29274644

Søreide K, Olsen F, Nymo LS, Kleive D, Lassen K (2018)
A nationwide cohort study of resection rates and short-term outcomes in open and laparoscopic distal pancreatectomy
HPB (Oxford), 21 (6), 669-678
DOI 10.1016/j.hpb.2018.10.006, PubMed 30391219

Publications 2017

Amrutkar M, Gladhaug IP (2017)
Pancreatic Cancer Chemoresistance to Gemcitabine
Cancers (Basel), 9 (11)
DOI 10.3390/cancers9110157, PubMed 29144412

Chellappa S, Hugenschmidt H, Hagness M, Subramani S, Melum E, Line PD, Labori KJ, Wiedswang G, Taskén K, Aandahl EM (2017)
CD8+ T Cells That Coexpress RORγt and T-bet Are Functionally Impaired and Expand in Patients with Distal Bile Duct Cancer
J Immunol, 198 (4), 1729-1739
DOI 10.4049/jimmunol.1600061, PubMed 28053236

Gladhaug IP, Skomedal T, Mørland J, Christoffersen T, Osnes JB (2017)
[Not Available]
Tidsskr Nor Laegeforen, 137 (14-15)
DOI 10.4045/tidsskr.17.0518, PubMed 28828823

Hauge T, Ånonsen KV, Buanes T (2017)
Management of Pancreatic Cysts (PC)- Based on Cumulative Knowledge
EC Gastroenterology and Digestive System, 02 (2017), s. 437-39
PublikaID 402

Haugvik SP, Basim Ibrahim I, Hedenström P, Valente R, Hayes AJ, Siuka D, Gladhaug IP, Capurso G (2017)
Smoking, alcohol and family history of cancer as risk factors for small intestinal neuroendocrine tumors: a systematic review and meta-analysis
Scand J Gastroenterol, 52 (8), 797-802
DOI 10.1080/00365521.2017.1310290, PubMed 28394712

Kleive D, Berstad AE, Sahakyan MA, Verbeke CS, Naper C, Haugvik SP, Gladhaug IP, Line PD, Labori KJ (2017)
Portal vein reconstruction using primary anastomosis or venous interposition allograft in pancreatic surgery
J Vasc Surg Venous Lymphat Disord, 6 (1), 66-74
DOI 10.1016/j.jvsv.2017.09.003, PubMed 29128301

Kleive D, Sahakyan MA, Berstad AE, Verbeke CS, Gladhaug IP, Edwin B, Fosby B, Line PD, Labori KJ (2017)
Trends in indications, complications and outcomes for venous resection during pancreatoduodenectomy
Br J Surg, 104 (11), 1558-1567
DOI 10.1002/bjs.10603, PubMed 28815556

Kuric E, Seiron P, Krogvold L, Edwin B, Buanes T, Hanssen KF, Skog O, Dahl-Jørgensen K, Korsgren O (2017)
Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes
Am J Pathol, 187 (3), 581-588
DOI 10.1016/j.ajpath.2016.11.002, PubMed 28212742

Labori KJ (2017)
Surgery
Tidsskr. Nor. Laegeforen., 137 (3), 219

Labori KJ, Brudvik KW (2017)
Follow-up After Surgery for Pancreatic Ductal Adenocarcinoma: Steps Toward an International Consensus
Pancreas, 46 (1), e2-e3
DOI 10.1097/MPA.0000000000000689, PubMed 27977631

Labori KJ, Guren MG, Brudvik KW, Røsok BI, Waage A, Nesbakken A, Larsen S, Dueland S, Edwin B, Bjørnbeth BA (2017)
Resection of synchronous liver metastases between radiotherapy and definitive surgery for locally advanced rectal cancer: short-term surgical outcomes, overall survival and recurrence-free survival
Colorectal Dis, 19 (8), 731-738
DOI 10.1111/codi.13622, PubMed 28181384

Labori KJ, Lassen K, Hoem D, Grønbech JE, Søreide JA, Mortensen K, Smaaland R, Sorbye H, Verbeke C, Dueland S (2017)
Neoadjuvant chemotherapy versus surgery first for resectable pancreatic cancer (Norwegian Pancreatic Cancer Trial - 1 (NorPACT-1)) - study protocol for a national multicentre randomized controlled trial
BMC Surg, 17 (1), 94
DOI 10.1186/s12893-017-0291-1, PubMed 28841916

Sahakyan MA, Edwin B, Kazaryan AM, Barkhatov L, Buanes T, Ignjatovic D, Labori KJ, Røsok BI (2017)
Perioperative outcomes and survival in elderly patients undergoing laparoscopic distal pancreatectomy
J Hepatobiliary Pancreat Sci, 24 (1), 42-48
DOI 10.1002/jhbp.409, PubMed 27794204

Sahakyan MA, Haugvik SP, Røsok BI, Kazaryan AM, Ignjatovic D, Buanes T, Labori KJ, Verbeke CS, Edwin B (2017)
Can standardized pathology examination increase the lymph node yield following laparoscopic distal pancreatectomy for ductal adenocarcinoma?
HPB (Oxford), 20 (2), 175-181
DOI 10.1016/j.hpb.2017.08.038, PubMed 28943397

Sahakyan MA, Kim SC, Kleive D, Kazaryan AM, Song KB, Ignjatovic D, Buanes T, Røsok BI, Labori KJ, Edwin B (2017)
Laparoscopic distal pancreatectomy for pancreatic ductal adenocarcinoma: Long-term oncologic outcomes after standard resection
Surgery, 162 (4), 802-811
DOI 10.1016/j.surg.2017.06.009, PubMed 28756944

Tjomsland V, Aasrum M, Christoffersen T, Gladhaug IP (2017)
Functional heterogeneity in tumor-derived human pancreatic stellate cells: Differential expression of HGF and implications for mitogenic signaling and migration in pancreatic cancer cells
Oncotarget, 8 (42), 71672-71684
DOI 10.18632/oncotarget.17800, PubMed 29069737

Vikum D, Nordøy I, Torp Andersen C, Fevang B, Line PD, Kolrud FK, Aukrust P, Buanes T (2017)
A Young, Immunocompetent Woman with Small Bowel and Hepatic Mucormycosis Successfully Treated with Aggressive Surgical Debridements and Antifungal Therapy
Case Rep Infect Dis, 2017, 4173246
DOI 10.1155/2017/4173246, PubMed 29435377

Ånonsen KV, Fagerland MW, Edwin B, Labori KJ, Kure EH, Hauge T, Buanes T (2017)
Cyst fluid CEA concentration discriminates between benign and premalignant/malignant pancreatic cystic lesions. A prospective cohort study. Short title: Diagnostic yield of pancreatic cyst fluid CEA analysis
EC Gastroenterology and Digestive System, 02, S. 426-436
PublikaID 401

Publications 2016

Haugvik SP, Kaemmerer D, Gaujoux S, Labori KJ, Verbeke CS, Gladhaug IP (2016)
Pathology and Surgical Treatment of High-Grade Pancreatic Neuroendocrine Carcinoma: an Evolving Landscape
Curr Oncol Rep, 18 (5), 28
DOI 10.1007/s11912-016-0518-9, PubMed 26984415

Haugvik SP, Vodák D, Haugom L, Hovig E, Gladhaug IP, Heim S, Micci F (2016)
Transcriptomic Profiling of Tumor Aggressiveness in Sporadic Nonfunctioning Pancreatic Neuroendocrine Neoplasms
Pancreas, 45 (8), 1196-203
DOI 10.1097/MPA.0000000000000610, PubMed 26918873

Johannessen LE, Panagopoulos I, Haugvik SP, Gladhaug IP, Heim S, Micci F (2016)
Upregulation of INS-IGF2 read-through expression and identification of a novel INS-IGF2 splice variant in insulinomas
Oncol Rep, 36 (5), 2653-2662
DOI 10.3892/or.2016.5132, PubMed 27667266

Kleive D, Berstad AE, Verbeke CS, Haugvik SP, Gladhaug IP, Line PD, Labori KJ (2016)
Cold-stored cadaveric venous allograft for superior mesenteric/portal vein reconstruction during pancreatic surgery
HPB (Oxford), 18 (7), 615-22
DOI 10.1016/j.hpb.2016.05.010, PubMed 27346143

Pozzi-Mucelli RM, Rinta-Kiikka I, Wünsche K, Laukkarinen J, Labori KJ, Ånonsen K, Verbeke C, Del Chiaro M, Kartalis N (2016)
Pancreatic MRI for the surveillance of cystic neoplasms: comparison of a short with a comprehensive imaging protocol
Eur Radiol, 27 (1), 41-50
DOI 10.1007/s00330-016-4377-4, PubMed 27246720

Sahakyan MA, Røsok BI, Kazaryan AM, Barkhatov L, Haugvik SP, Fretland ÅA, Ignjatovic D, Labori KJ, Edwin B (2016)
Role of laparoscopic enucleation in the treatment of pancreatic lesions: case series and case-matched analysis
Surg Endosc, 31 (5), 2310-2316
DOI 10.1007/s00464-016-5233-y, PubMed 27620912

Sahakyan MA, Røsok BI, Kazaryan AM, Barkhatov L, Lai X, Kleive D, Ignjatovic D, Labori KJ, Edwin B (2016)
Impact of obesity on surgical outcomes of laparoscopic distal pancreatectomy: A Norwegian single-center study
Surgery, 160 (5), 1271-1278
DOI 10.1016/j.surg.2016.05.046, PubMed 27498300

Sahakyan MA, Yaqub S, Kazaryan AM, Villanger O, Berstad AE, Labori KJ, Edwin B, Røsok BI (2016)
Laparoscopic Completion Pancreatectomy for Local Recurrence in the Pancreatic Remnant after Pancreaticoduodenectomy: Case Reports and Review of the Literature
J Gastrointest Cancer, 47 (4), 509-513
DOI 10.1007/s12029-015-9796-y, PubMed 26732389

Sandhu V, Wedge DC, Bowitz Lothe IM, Labori KJ, Dentro SC, Buanes T, Skrede ML, Dalsgaard AM, Munthe E, Myklebost O, Lingjærde OC, Børresen-Dale AL, Ikdahl T, Van Loo P, Nord S, Kure EH (2016)
The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma
Cancer Res, 76 (17), 5092-102
DOI 10.1158/0008-5472.CAN-16-0658, PubMed 27488532

Søreide K, Labori KJ (2016)
Risk factors and preventive strategies for post-operative pancreatic fistula after pancreatic surgery: a comprehensive review
Scand J Gastroenterol, 51 (10), 1147-54
DOI 10.3109/00365521.2016.1169317, PubMed 27216233

Tjomsland V, Pomianowska E, Aasrum M, Sandnes D, Verbeke CS, Gladhaug IP (2016)
Profile of MMP and TIMP Expression in Human Pancreatic Stellate Cells: Regulation by IL-1α and TGFβ and Implications for Migration of Pancreatic Cancer Cells
Neoplasia, 18 (7), 447-56
DOI 10.1016/j.neo.2016.06.003, PubMed 27435927

Tjomsland V, Sandnes D, Pomianowska E, Cizmovic ST, Aasrum M, Brusevold IJ, Christoffersen T, Gladhaug IP (2016)
The TGFβ-SMAD3 pathway inhibits IL-1α induced interactions between human pancreatic stellate cells and pancreatic carcinoma cells and restricts cancer cell migration
J Exp Clin Cancer Res, 35 (1), 122
DOI 10.1186/s13046-016-0400-5, PubMed 27473228

Verbeke CS, Gladhaug IP (2016)
Dissection of Pancreatic Resection Specimens
Surg Pathol Clin, 9 (4), 523-538
DOI 10.1016/j.path.2016.05.001, PubMed 27926357

Publications 2015

Anonsen KV, Buanes T, Rosok BI, Hauge T, Edwin B (2015)
Outcome of Laparoscopic Surgery in Patients with Cystic Lesions in the Distal Pancreas
J. Pancreas, 16 (3), 266-270

Baekelandt BM, Hjermstad MJ, Nordby T, Fagerland MW, Kure EH, Heiberg T, Buanes T, Labori KJ (2015)
Preoperative cognitive function predicts survival in patients with resectable pancreatic ductal adenocarcinoma
HPB (Oxford), 18 (3), 247-54
DOI 10.1016/j.hpb.2015.09.004, PubMed 27017164

Chellappa S, Hugenschmidt H, Hagness M, Line PD, Labori KJ, Wiedswang G, Taskén K, Aandahl EM (2015)
Regulatory T cells that co-express RORγt and FOXP3 are pro-inflammatory and immunosuppressive and expand in human pancreatic cancer
Oncoimmunology, 5 (4), e1102828
DOI 10.1080/2162402X.2015.1102828, PubMed 27141387

Costa-Silva B, Aiello NM, Ocean AJ, Singh S, Zhang H, Thakur BK, Becker A, Hoshino A, Mark MT, Molina H, Xiang J, Zhang T, Theilen TM, García-Santos G, Williams C, Ararso Y, Huang Y, Rodrigues G, Shen TL, Labori KJ, Lothe IM, Kure EH, Hernandez J, Doussot A, Ebbesen SH et al. (2015)
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
Nat Cell Biol, 17 (6), 816-26
DOI 10.1038/ncb3169, PubMed 25985394

Hamfjord J, Saldova R, Stöckmann H, Sandhu V, Bowitz Lothe IM, Buanes T, Lingjærde OC, Labori KJ, Rudd PM, Kure EH (2015)
Serum N-Glycome Characterization in Patients with Resectable Periampullary Adenocarcinoma
J Proteome Res, 14 (12), 5144-56
DOI 10.1021/acs.jproteome.5b00395, PubMed 26515733

Haugvik SP, Hedenström P, Korsæth E, Valente R, Hayes A, Siuka D, Maisonneuve P, Gladhaug IP, Lindkvist B, Capurso G (2015)
Diabetes, smoking, alcohol use, and family history of cancer as risk factors for pancreatic neuroendocrine tumors: a systematic review and meta-analysis
Neuroendocrinology, 101 (2), 133-42
DOI 10.1159/000375164, PubMed 25613442

Haugvik SP, Janson ET, Österlund P, Langer SW, Falk RS, Labori KJ, Vestermark LW, Grønbæk H, Gladhaug IP, Sorbye H (2015)
Surgical Treatment as a Principle for Patients with High-Grade Pancreatic Neuroendocrine Carcinoma: A Nordic Multicenter Comparative Study
Ann Surg Oncol, 23 (5), 1721-8
DOI 10.1245/s10434-015-5013-2, PubMed 26678407

Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, King T, Bojmar L, Davies AE, Ararso Y, Zhang T, Zhang H, Hernandez J, Weiss JM, Dumont-Cole VD, Kramer K et al. (2015)
Tumour exosome integrins determine organotropic metastasis
Nature, 527 (7578), 329-35
DOI 10.1038/nature15756, PubMed 26524530

Krogvold L, Skog O, Sundström G, Edwin B, Buanes T, Hanssen KF, Ludvigsson J, Grabherr M, Korsgren O, Dahl-Jørgensen K (2015)
Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study
Diabetes, 64 (7), 2506-12
DOI 10.2337/db14-1911, PubMed 25677915

Krogvold L, Wiberg A, Edwin B, Buanes T, Jahnsen FL, Hanssen KF, Larsson E, Korsgren O, Skog O, Dahl-Jørgensen K (2015)
Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes
Diabetologia, 59 (3), 492-501
DOI 10.1007/s00125-015-3820-4, PubMed 26602422

Labori KJ, Haugvik SP, Line PD (2015)
Letter to the editor: Multidisciplinary management of pancreatic neuroendocrine tumors--the importance of an aggressive surgical approach
Scand J Gastroenterol, 51 (3), 383-4
DOI 10.3109/00365521.2015.1094125, PubMed 26458136

Labori KJ, Katz MH, Tzeng CW, Bjørnbeth BA, Cvancarova M, Edwin B, Kure EH, Eide TJ, Dueland S, Buanes T, Gladhaug IP (2015)
Impact of early disease progression and surgical complications on adjuvant chemotherapy completion rates and survival in patients undergoing the surgery first approach for resectable pancreatic ductal adenocarcinoma - A population-based cohort study
Acta Oncol, 55 (3), 265-77
DOI 10.3109/0284186X.2015.1068445, PubMed 26213211

Labori KJ, Schulz A, Drolsum A, Guren MG, Kløw NE, Bjørnbeth BA (2015)
Radiofrequency ablation of unresectable colorectal liver metastases: trends in management and outcome during a decade at a single center
Acta Radiol Open, 4 (7), 2058460115580877
DOI 10.1177/2058460115580877, PubMed 26346740

Labori KJ, Verbeke CS, Gladhaug IP (2015)
Information needs among patients and a surveillance strategy after surgery for pancreatic and periampullary cancer
HPB (Oxford), 17 (7), 659
DOI 10.1111/hpb.12411, PubMed 25776256

Otterdal K, Haukeland JW, Yndestad A, Dahl TB, Holm S, Segers FM, Gladhaug IP, Konopski Z, Damås JK, Halvorsen B, Aukrust P (2015)
Increased Serum Levels of LIGHT/TNFSF14 in Nonalcoholic Fatty Liver Disease: Possible Role in Hepatic Inflammation
Clin Transl Gastroenterol, 6 (7), e95
DOI 10.1038/ctg.2015.23, PubMed 26133108

Sahakyan MA, Kazaryan AM, Rawashdeh M, Fuks D, Shmavonyan M, Haugvik SP, Labori KJ, Buanes T, Røsok BI, Ignjatovic D, Abu Hilal M, Gayet B, Kim SC, Edwin B (2015)
Laparoscopic distal pancreatectomy for pancreatic ductal adenocarcinoma: results of a multicenter cohort study on 196 patients
Surg Endosc, 30 (8), 3409-18
DOI 10.1007/s00464-015-4623-x, PubMed 26514135

Sandhu V, Bowitz Lothe IM, Labori KJ, Skrede ML, Hamfjord J, Dalsgaard AM, Buanes T, Dube G, Kale MM, Sawant S, Kulkarni-Kale U, Børresen-Dale AL, Lingjærde OC, Kure EH (2015)
Differential expression of miRNAs in pancreatobiliary type of periampullary adenocarcinoma and its associated stroma
Mol Oncol, 10 (2), 303-16
DOI 10.1016/j.molonc.2015.10.011, PubMed 26590090

Schulz A, Godt JC, Dormagen JB, Holtedahl JE, Bogsrud TV, Labori KJ, Kløw NE, Bach-Gansmo T (2015)
Respiratory gated PET/CT of the liver: A novel method and its impact on the detection of colorectal liver metastases
Eur J Radiol, 84 (8), 1424-1431
DOI 10.1016/j.ejrad.2015.05.011, PubMed 26044293

Schulz A, Viktil E, Godt JC, Johansen CK, Dormagen JB, Holtedahl JE, Labori KJ, Bach-Gansmo T, Kløw NE (2015)
Diagnostic performance of CT, MRI and PET/CT in patients with suspected colorectal liver metastases: the superiority of MRI
Acta Radiol, 57 (9), 1040-8
DOI 10.1177/0284185115617349, PubMed 26622057

Skog O, Korsgren S, Wiberg A, Danielsson A, Edwin B, Buanes T, Krogvold L, Korsgren O, Dahl-Jørgensen K (2015)
Expression of human leukocyte antigen class I in endocrine and exocrine pancreatic tissue at onset of type 1 diabetes
Am J Pathol, 185 (1), 129-38
DOI 10.1016/j.ajpath.2014.09.004, PubMed 25524212

Publications 2014

Haugvik SP, Gaujoux S, Røsok B, Gladhaug IP, Dousset B, Edwin B (2014)
Laparoscopic versus open pancreas resection for neuroendocrine tumours: need for evaluation of oncological outcomes
HPB (Oxford), 16 (9), 871
DOI 10.1111/hpb.12254, PubMed 25099232

Haugvik SP, Gorunova L, Haugom L, Eibak AM, Gladhaug IP, Heim S, Micci F (2014)
Loss of 11p11 is a frequent and early event in sporadic nonfunctioning pancreatic neuroendocrine neoplasms
Oncol Rep, 32 (3), 906-12
DOI 10.3892/or.2014.3328, PubMed 25018013

Krogvold L, Edwin B, Buanes T, Frisk G, Skog O, Anagandula M, Korsgren O, Undlien D, Eike MC, Richardson SJ, Leete P, Morgan NG, Oikarinen S, Oikarinen M, Laiho JE, Hyöty H, Ludvigsson J, Hanssen KF, Dahl-Jørgensen K (2014)
Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes
Diabetes, 64 (5), 1682-7
DOI 10.2337/db14-1370, PubMed 25422108

Krogvold L, Edwin B, Buanes T, Ludvigsson J, Korsgren O, Hyöty H, Frisk G, Hanssen KF, Dahl-Jørgensen K (2014)
Pancreatic biopsy by minimal tail resection in live adult patients at the onset of type 1 diabetes: experiences from the DiViD study
Diabetologia, 57 (4), 841-3
DOI 10.1007/s00125-013-3155-y, PubMed 24429579

Pomianowska E, Bjørnbeth BA, Rojahn AE, Labori KJ, Yaqub S (2014)
[Liver cyst from the East]
Tidsskr Nor Laegeforen, 134 (7), 716
DOI 10.4045/tidsskr.13.1480, PubMed 24721860

Pomianowska E, Sandnes D, Grzyb K, Schjølberg AR, Aasrum M, Tveteraas IH, Tjomsland V, Christoffersen T, Gladhaug IP (2014)
Inhibitory effects of prostaglandin E2 on collagen synthesis and cell proliferation in human stellate cells from pancreatic head adenocarcinoma
BMC Cancer, 14, 413
DOI 10.1186/1471-2407-14-413, PubMed 24912820

Pomianowska E, Schjølberg AR, Clausen OP, Gladhaug IP (2014)
COX-2 overexpression in resected pancreatic head adenocarcinomas correlates with favourable prognosis
BMC Cancer, 14, 458
DOI 10.1186/1471-2407-14-458, PubMed 24950702

Sandhu V, Bowitz Lothe IM, Labori KJ, Lingjærde OC, Buanes T, Dalsgaard AM, Skrede ML, Hamfjord J, Haaland T, Eide TJ, Børresen-Dale AL, Ikdahl T, Kure EH (2014)
Molecular signatures of mRNAs and miRNAs as prognostic biomarkers in pancreatobiliary and intestinal types of periampullary adenocarcinomas
Mol Oncol, 9 (4), 758-71
DOI 10.1016/j.molonc.2014.12.002, PubMed 25579086

Vedeld HM, Andresen K, Eilertsen IA, Nesbakken A, Seruca R, Gladhaug IP, Thiis-Evensen E, Rognum TO, Boberg KM, Lind GE (2014)
The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers
Int J Cancer, 136 (4), 844-53
DOI 10.1002/ijc.29039, PubMed 24948044

Yaqub S, Mala T, Mathisen O, Edwin B, Fosby B, Berntzen DT, Abildgaard A, Labori KJ (2014)
Management of Injury to the Common Bile Duct in a Patient with Roux-en-Y Gastric Bypass
Case Rep Surg, 2014, 938532
DOI 10.1155/2014/938532, PubMed 25161795

Publications 2013

Brudvik KW, Bains SJ, Seeberg LT, Labori KJ, Waage A, Taskén K, Aandahl EM, Bjørnbeth BA (2013)
Aggressive treatment of patients with metastatic colorectal cancer increases survival: a scandinavian single-center experience
HPB Surg, 2013, 727095
DOI 10.1155/2013/727095, PubMed 23840074

Hagness M, Foss A, Line PD, Scholz T, Jørgensen PF, Fosby B, Boberg KM, Mathisen O, Gladhaug IP, Egge TS, Solberg S, Hausken J, Dueland S (2013)
Liver transplantation for nonresectable liver metastases from colorectal cancer
Ann Surg, 257 (5), 800-6
DOI 10.1097/SLA.0b013e3182823957, PubMed 23360920

Haugvik SP, Labori KJ, Waage A, Line PD, Mathisen Ø, Gladhaug IP (2013)
Pancreatic surgery with vascular reconstruction in patients with locally advanced pancreatic neuroendocrine tumors
J Gastrointest Surg, 17 (7), 1224-32
DOI 10.1007/s11605-013-2221-6, PubMed 23670519

Haugvik SP, Marangos IP, Røsok BI, Pomianowska E, Gladhaug IP, Mathisen O, Edwin B (2013)
Long-term outcome of laparoscopic surgery for pancreatic neuroendocrine tumors
World J Surg, 37 (3), 582-90
DOI 10.1007/s00268-012-1893-5, PubMed 23263686

Heiberg T, Nordby T, Kvien TK, Buanes T (2013)
Development and preliminary validation of the pancreatic cancer disease impact score
Support Care Cancer, 21 (6), 1677-84
DOI 10.1007/s00520-012-1713-3, PubMed 23314652

Nordby T, Hugenschmidt H, Fagerland MW, Ikdahl T, Buanes T, Labori KJ (2013)
Follow-up after curative surgery for pancreatic ductal adenocarcinoma: asymptomatic recurrence is associated with improved survival
Eur J Surg Oncol, 39 (6), 559-66
DOI 10.1016/j.ejso.2013.02.020, PubMed 23498362

Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
Pancreatology, 13 (2), 180-5
DOI 10.1016/j.pan.2013.01.003, PubMed 23561977

Nordby T, Ikdahl T, Lothe IM, Ånonsen K, Hauge T, Edwin B, Line PD, Labori KJ, Buanes T (2013)
Opportunities of improvement in the management of pancreatic and periampullary tumors
Scand J Gastroenterol, 48 (5), 617-25
DOI 10.3109/00365521.2013.781218, PubMed 23597153

Søndergaard EB, Pedersen JH, Kleive D (2013)
Infected bronchogenic cyst causing dysphagia and retrosternal pain
Clin Respir J, 7 (2), e13-4
DOI 10.1111/j.1752-699X.2012.00296.x, PubMed 22583776

Verbeke CS, Gladhaug IP (2013)
Authors' reply: Resection margin involvement and tumour origin in pancreatic head cancer (Br J Surg 2012; 99: 1036-1049)
Br J Surg, 100 (2), 299
DOI 10.1002/bjs.9016, PubMed 23239483

Publications 2012

Buanes T (2012)
The prognosis for pancreatic cancer patients--better than feared
Tidsskr Nor Laegeforen, 132 (1), 7
DOI 10.4045/tidsskr.11.1242, PubMed 22240836

Haugvik SP, Labori KJ, Edwin B, Mathisen Ø, Gladhaug IP (2012)
Surgical treatment of sporadic pancreatic neuroendocrine tumors: a state of the art review
ScientificWorldJournal, 2012, 357475
DOI 10.1100/2012/357475, PubMed 23304085

Haugvik SP, Røsok BI, Edwin B, Gladhaug IP, Mathisen Ø (2012)
Concomitant Nonfunctional Pancreatic Neuroendocrine Tumor and Gastric GIST in a Patient Without Neurofibromatosis Type 1
J Gastrointest Cancer, 43 Suppl 1, S171-4
DOI 10.1007/s12029-011-9344-3, PubMed 22083533

Marangos IP, Buanes T, Røsok BI, Kazaryan AM, Rosseland AR, Grzyb K, Villanger O, Mathisen Ø, Gladhaug IP, Edwin B (2012)
Laparoscopic resection of exocrine carcinoma in central and distal pancreas results in a high rate of radical resections and long postoperative survival
Surgery, 151 (5), 717-23
DOI 10.1016/j.surg.2011.12.016, PubMed 22284762

Monrad-Hansen PW, Buanes T, Young VS, Langebrekke A, Qvigstad E (2012)
Endometriosis of the pancreas
J Minim Invasive Gynecol, 19 (4), 521-3
DOI 10.1016/j.jmig.2012.03.011, PubMed 22748958

Pomianowska E, Grzyb K, Westgaard A, Clausen OP, Gladhaug IP (2012)
Reclassification of tumour origin in resected periampullary adenocarcinomas reveals underestimation of distal bile duct cancer
Eur J Surg Oncol, 38 (11), 1043-50
DOI 10.1016/j.ejso.2012.07.113, PubMed 22883964

Pomianowska E, Westgaard A, Mathisen Ø, Clausen OP, Gladhaug IP (2012)
Prognostic relevance of number and ratio of metastatic lymph nodes in resected pancreatic, ampullary, and distal bile duct carcinomas
Ann Surg Oncol, 20 (1), 233-41
DOI 10.1245/s10434-012-2592-z, PubMed 22893118

Schulz A, Dormagen JB, Drolsum A, Bjørnbeth BA, Labori KJ, Kløw NE (2012)
Impact of contrast-enhanced intraoperative ultrasound on operation strategy in case of colorectal liver metastasis
Acta Radiol, 53 (10), 1081-7
DOI 10.1258/ar.2012.120049, PubMed 23081954

Søndergaard EB, Kleive D, Siemsen M (2012)
[Infected bronchogenic cysts may cause recurrence of bronchial infection]
Ugeskr Laeger, 174 (19), 1312-3
PubMed 22564690

Verbeke CS, Gladhaug IP (2012)
Resection margin involvement and tumour origin in pancreatic head cancer
Br J Surg, 99 (8), 1036-49
DOI 10.1002/bjs.8734, PubMed 22517199

Westgaard A, Pomianowska E, Clausen OP, Gladhaug IP (2012)
Intestinal-type and pancreatobiliary-type adenocarcinomas: how does ampullary carcinoma differ from other periampullary malignancies?
Ann Surg Oncol, 20 (2), 430-9
DOI 10.1245/s10434-012-2603-0, PubMed 22956064

Publications 2011

Haugen F, Labori KJ, Noreng HJ, Buanes T, Iversen PO, Drevon CA (2011)
Altered expression of genes in adipose tissues associated with reduced fat mass in patients with pancreatic cancer
Arch Physiol Biochem, 117 (2), 78-87
DOI 10.3109/13813455.2011.560609, PubMed 21457003

Haukeland JW, Dahl TB, Yndestad A, Gladhaug IP, Løberg EM, Haaland T, Konopski Z, Wium C, Aasheim ET, Johansen OE, Aukrust P, Halvorsen B, Birkeland KI (2011)
Fetuin A in nonalcoholic fatty liver disease: in vivo and in vitro studies
Eur J Endocrinol, 166 (3), 503-10
DOI 10.1530/EJE-11-0864, PubMed 22170794

Verbeke CS, Knapp J, Gladhaug IP (2011)
Tumour growth is more dispersed in pancreatic head cancers than in rectal cancer: implications for resection margin assessment
Histopathology, 59 (6), 1111-21
DOI 10.1111/j.1365-2559.2011.04056.x, PubMed 22175891

Wedén S, Klemp M, Gladhaug IP, Møller M, Eriksen JA, Gaudernack G, Buanes T (2011)
Long-term follow-up of patients with resected pancreatic cancer following vaccination against mutant K-ras
Int J Cancer, 128 (5), 1120-8
DOI 10.1002/ijc.25449, PubMed 20473937

Westgaard A, Clausen OP, Gladhaug IP (2011)
Survival estimates after pancreatoduodenectomy skewed by non-standardized histopathology reports
APMIS, 119 (10), 689-700
DOI 10.1111/j.1600-0463.2011.02783.x, PubMed 21917006

Publications 2010

Dahl TB, Haukeland JW, Yndestad A, Ranheim T, Gladhaug IP, Damås JK, Haaland T, Løberg EM, Arntsen B, Birkeland K, Bjøro K, Ulven SM, Konopski Z, Nebb HI, Aukrust P, Halvorsen B (2010)
Intracellular nicotinamide phosphoribosyltransferase protects against hepatocyte apoptosis and is down-regulated in nonalcoholic fatty liver disease
J Clin Endocrinol Metab, 95 (6), 3039-47
DOI 10.1210/jc.2009-2148, PubMed 20392873

Gladhaug IP, Westgaard A, Schjølberg AR, Burum-Auensen E, Pomianowska E, Clausen OP (2010)
Spindle proteins in resected pancreatic head adenocarcinomas: BubR1 is an independent prognostic factor in pancreatobiliary-type tumours
Histopathology, 56 (3), 345-55
DOI 10.1111/j.1365-2559.2010.03489.x, PubMed 20459534

Labori KJ (2010)
[Spontaneous hemoperitoneum]
Tidsskr Nor Laegeforen, 130 (21), 2129
DOI 10.4045/tidsskr.10.0967, PubMed 21052115

Pomianowska E, Gladhaug IP, Grzyb K, Røsok BI, Edwin B, Bergestuen DS, Mathisen O (2010)
Survival following resection of pancreatic endocrine tumors: importance of R-status and the WHO and TNM classification systems
Scand J Gastroenterol, 45 (7-8), 971-9
DOI 10.3109/00365521003782363, PubMed 20441530

Publications 2009

Labori KJ, Lyberg T, Raeder MG (2009)
Effects of bilirubin ditaurate overload on canalicular membrane function and ultrastructure of the pig liver
Injury, 40 (8), 868-72
DOI 10.1016/j.injury.2008.11.017, PubMed 19376516

Labori KJ, Trondsen E, Buanes T, Hauge T (2009)
Endoscopic sealing of pancreatic fistulas: four case reports and review of the literature
Scand J Gastroenterol, 44 (12), 1491-6
DOI 10.3109/00365520903362610, PubMed 19883276

Mathisen Ø, Dorenberg E, Edwin B, Gladhaug I, Hafsahl G, Røkke O (2009)
[Portal vein embolization before surgery for liver tumours]
Tidsskr Nor Laegeforen, 129 (1), 29-32
DOI 10.4045/tidsskr.2009.32875, PubMed 19119294

Nakken KE, Nygard S, Haaland TK, Berge KE, Ødegaard A, Labori KJ, Raeder MG (2009)
Gene expression profiles reflect sclerosing cholangitis activity in abcb4 (-/-) mice
Scand J Gastroenterol, 44 (2), 211-8
DOI 10.1080/00365520802400867, PubMed 18785065

Westgaard A, Larønningen S, Mellem C, Eide TJ, Clausen OP, Møller B, Gladhaug IP (2009)
Are survival predictions reliable? Hospital volume versus standardisation of histopathologic reporting for accuracy of survival estimates after pancreatoduodenectomy for adenocarcinoma
Eur J Cancer, 45 (16), 2850-9
DOI 10.1016/j.ejca.2009.03.019, PubMed 19376696

Westgaard A, Schjølberg AR, Cvancarova M, Eide TJ, Clausen OP, Gladhaug IP (2009)
Differentiation markers in pancreatic head adenocarcinomas: MUC1 and MUC4 expression indicates poor prognosis in pancreatobiliary differentiated tumours
Histopathology, 54 (3), 337-47
DOI 10.1111/j.1365-2559.2009.03227.x, PubMed 19236510

Yndestad A, Haukeland JW, Dahl TB, Bjøro K, Gladhaug IP, Berge C, Damås JK, Haaland T, Løberg EM, Linnestad P, Birkeland K, Konopski Z, Halvorsen B, Berge RK, Aukrust P (2009)
A complex role of activin A in non-alcoholic fatty liver disease
Am J Gastroenterol, 104 (9), 2196-205
DOI 10.1038/ajg.2009.318, PubMed 19532130

Publications 2008

Frich L, Brabrand K, Aaløkken TM, Edwin B, Gladhaug IP (2008)
[Radiofrequency ablation of colorectal liver metastases]
Tidsskr Nor Laegeforen, 128 (1), 57-60
PubMed 18183060

Nakken KE, Labori KJ, Rødningen OK, Nakken S, Berge KE, Eiklid K, Raeder MG (2008)
ABCB4 sequence variations in young adults with cholesterol gallstone disease
Liver Int, 29 (5), 743-7
DOI 10.1111/j.1478-3231.2008.01914.x, PubMed 19018976

Westgaard A, Tafjord S, Farstad IN, Cvancarova M, Eide TJ, Mathisen O, Clausen OP, Gladhaug IP (2008)
Resectable adenocarcinomas in the pancreatic head: the retroperitoneal resection margin is an independent prognostic factor
BMC Cancer, 8, 5
DOI 10.1186/1471-2407-8-5, PubMed 18194510

Westgaard A, Tafjord S, Farstad IN, Cvancarova M, Eide TJ, Mathisen O, Clausen OP, Gladhaug IP (2008)
Pancreatobiliary versus intestinal histologic type of differentiation is an independent prognostic factor in resected periampullary adenocarcinoma
BMC Cancer, 8, 170
DOI 10.1186/1471-2407-8-170, PubMed 18547417

Publications 2007

Frich L, Hagen G, Brabrand K, Edwin B, Mathisen O, Aaløkken TM, Gladhaug IP (2007)
Local tumor progression after radiofrequency ablation of colorectal liver metastases: evaluation of ablative margin and three-dimensional volumetric analysis
J Vasc Interv Radiol, 18 (9), 1134-40
DOI 10.1016/j.jvir.2007.06.007, PubMed 17804776

Frich L, Halvorsen PS, Skulstad H, Damås JK, Gladhaug IP (2007)
Microbubbles in the pulmonary artery generated during experimental hepatic radiofrequency ablation is correlated with increased pulmonary arterial pressure
J Vasc Interv Radiol, 18 (3), 437-42
DOI 10.1016/j.jvir.2006.12.010, PubMed 17377191

Gaarder C, Naess PA, Eken T, Skaga NO, Pillgram-Larsen J, Klow NE, Buanes T (2007)
Liver injuries--improved results with a formal protocol including angiography
Injury, 38 (9), 1075-83
DOI 10.1016/j.injury.2007.02.001, PubMed 17706220

Nakken KE, Nygård S, Haaland T, Berge KE, Arnkvaern K, Ødegaard A, Labori KJ, Raeder MG (2007)
Multiple inflammatory-, tissue remodelling- and fibrosis genes are differentially transcribed in the livers of Abcb4 (-/ - ) mice harbouring chronic cholangitis
Scand J Gastroenterol, 42 (10), 1245-55
DOI 10.1080/00365520701320521, PubMed 17852852

Publications 2006

Frich L, Bjørnland K, Pettersen S, Clausen OP, Gladhaug IP (2006)
Increased activity of matrix metalloproteinase 2 and 9 after hepatic radiofrequency ablation
J Surg Res, 135 (2), 297-304
DOI 10.1016/j.jss.2006.05.010, PubMed 16934296

Frich L, Hol PK, Roy S, Mala T, Edwin B, Clausen OP, Gladhaug IP (2006)
Experimental hepatic radiofrequency ablation using wet electrodes: electrode-to-vessel distance is a significant predictor for delayed portal vein thrombosis
Eur Radiol, 16 (9), 1990-9
DOI 10.1007/s00330-006-0177-6, PubMed 16541225

Frich L, Mala T, Gladhaug IP (2006)
Hepatic radiofrequency ablation using perfusion electrodes in a pig model: effect of the Pringle manoeuvre
Eur J Surg Oncol, 32 (5), 527-32
DOI 10.1016/j.ejso.2006.02.021, PubMed 16595167

Gaarder C, Dormagen JB, Eken T, Skaga NO, Klow NE, Pillgram-Larsen J, Buanes T, Naess PA (2006)
Nonoperative management of splenic injuries: improved results with angioembolization
J Trauma, 61 (1), 192-8
DOI 10.1097/01.ta.0000223466.62589.d9, PubMed 16832270

Labori KJ, Hjermstad MJ, Wester T, Buanes T, Loge JH (2006)
Symptom profiles and palliative care in advanced pancreatic cancer: a prospective study
Support Care Cancer, 14 (11), 1126-33
DOI 10.1007/s00520-006-0067-0, PubMed 16601947

Publications 2005

Frich L, Edwin B, Brabrand K, Rosseland AR, Mala T, Mathisen O, Gladhaug I (2005)
Gastric perforation after percutaneous radiofrequency ablation of a colorectal liver metastasis in a patient with adhesions in the peritoneal cavity
AJR Am J Roentgenol, 184 (3 Suppl), S120-2
DOI 10.2214/ajr.184.3_supplement.0184s120, PubMed 15728002

Gaarder C, Naess PA, Buanes T, Pillgram-Larsen J (2005)
Advanced surgical trauma care training with a live porcine model
Injury, 36 (6), 718-24
DOI 10.1016/j.injury.2004.12.024, PubMed 15910823

Gaarder C, Skaga NO, Eken T, Pillgram-Larsen J, Buanes T, Naess PA (2005)
The impact of patient volume on surgical trauma training in a Scandinavian trauma centre
Injury, 36 (11), 1288-92
DOI 10.1016/j.injury.2005.06.034, PubMed 16122752

Mala T, Edwin B, Rosseland AR, Gladhaug I, Fosse E, Mathisen O (2005)
Laparoscopic liver resection: experience of 53 procedures at a single center
J Hepatobiliary Pancreat Surg, 12 (4), 298-303
DOI 10.1007/s00534-005-0974-3, PubMed 16133696

Roussa E, Bertram J, Berge KE, Labori KJ, Thévenod F, Raeder MG (2005)
Differential regulation of vacuolar H+ -ATPase and Na+/H+ exchanger 3 in rat cholangiocytes after bile duct ligation
Histochem Cell Biol, 125 (4), 419-28
DOI 10.1007/s00418-005-0082-0, PubMed 16267653

Publications 2004

Edwin B, Mala T, Mathisen Ø, Gladhaug I, Buanes T, Lunde OC, Søreide O, Bergan A, Fosse E (2004)
Laparoscopic resection of the pancreas: a feasibility study of the short-term outcome
Surg Endosc, 18 (3), 407-11
DOI 10.1007/s00464-003-9007-y, PubMed 14752628

Frich L, Bjørnerud A, Fossheim S, Tillung T, Gladhaug I (2004)
Experimental application of thermosensitive paramagnetic liposomes for monitoring magnetic resonance imaging guided thermal ablation
Magn Reson Med, 52 (6), 1302-9
DOI 10.1002/mrm.20289, PubMed 15562487

Gaarder C, Naess PA, Schwab CW, Bjørnbeth BA, Buanes T, Pillgram-Larsen J (2004)
[Vacuum pack technique--a good method for temporal abdominal closure]
Tidsskr Nor Laegeforen, 124 (21), 2760-2
PubMed 15534669

Hellund JC, Labori KJ, Bjørnbeth BA, Gjesdal KI, Geitung JT (2004)
MRI of slow flow in artificial duct in swine
Eur Radiol, 14 (9), 1692-7
DOI 10.1007/s00330-003-2212-1, PubMed 14767600

Labori KJ, Raeder MG (2004)
Diagnostic approach to the patient with jaundice following trauma
Scand J Surg, 93 (3), 176-83
DOI 10.1177/145749690409300302, PubMed 15544071

Mala T, Edwin B, Mathisen Ø, Tillung T, Fosse E, Bergan A, SØreide O, Gladhaug I (2004)
Cryoablation of colorectal liver metastases: minimally invasive tumour control
Scand J Gastroenterol, 39 (6), 571-8
DOI 10.1080/00365520410000510, PubMed 15223683

Stensvold E, Aass N, Gladhaug I, Stenwig AE, Claussen OP, Fosså SD (2004)
Erroneous diagnosis of pancreatic cancer after radiotherapy of testicular cancer
Eur J Surg Oncol, 30 (3), 352-5
DOI 10.1016/j.ejso.2003.09.006, PubMed 15028321

Publications 2003

Labori KJ, Bjørnbeth BA, Raeder MG (2003)
Aetiology and prognostic implication of severe jaundice in surgical trauma patients
Scand J Gastroenterol, 38 (1), 102-8
DOI 10.1080/00365520310000519, PubMed 12608472

Labori KJ, Gaarder C, Naess PA (2003)
[Traumatic abdominal wall hernia in children]
Tidsskr Nor Laegeforen, 123 (6), 804-5
PubMed 12693121

Mala T, Edwin B, Tillung T, Kristian Hol P, Søreide O, Gladhaug I (2003)
Percutaneous cryoablation of colorectal liver metastases: potentiated by two consecutive freeze-thaw cycles
Cryobiology, 46 (1), 99-102
DOI 10.1016/s0011-2240(02)00163-3, PubMed 12623032

Mala T, Frich L, Aurdal L, Clausen OP, Edwin B, Soreide O, Gladhaug I (2003)
Intraoperative contrast-enhanced MR-imaging as predictor of tissue damage during cryoablation of porcine liver
Magn Reson Imaging, 21 (7), 733-40
DOI 10.1016/s0730-725x(03)00176-0, PubMed 14559337

Mala T, Frich L, Aurdal L, Clausen OP, Edwin B, Søreide O, Gladhaug IP (2003)
Hepatic vascular inflow occlusion enhances tissue destruction during cryoablation of porcine liver
J Surg Res, 115 (2), 265-71
DOI 10.1016/j.jss.2003.07.009, PubMed 14697293

Publications 2002

Hellund JC, Geitung JT, Meo AM, Angelsen JH, Munkvik M, Trondsen E, Buanes T (2002)
[Secretin stimulated magnetic resonance cholangiopancreatography in diseases of the biliary and pancreatic ducts]
Tidsskr Nor Laegeforen, 122 (7), 691-4
PubMed 11998731

Labori KJ, Arnkvaern K, Bjørnbeth BA, Press CM, Raeder MG (2002)
Cholestatic effect of large bilirubin loads and cholestasis protection conferred by cholic acid co-infusion: a molecular and ultrastructural study
Scand J Gastroenterol, 37 (5), 585-96
DOI 10.1080/00365520252903152, PubMed 12059062

Labori KJ, Carlsen E (2002)
Treatment of bleeding peristomal varices
Eur J Surg, 168 (11), 654-6
DOI 10.1080/11024150201680017, PubMed 12699107

Mala T, Edwin B, Gladhaug I, Fosse E, Søreide O, Bergan A, Mathisen O (2002)
A comparative study of the short-term outcome following open and laparoscopic liver resection of colorectal metastases
Surg Endosc, 16 (7), 1059-63
DOI 10.1007/s00464-001-9176-5, PubMed 12165823

Mala T, Edwin B, Gladhaug I, Søreide O, Fosse E, Mathisen Ø, Bergan A (2002)
[Laparoscopic resection of the liver]
Tidsskr Nor Laegeforen, 122 (29), 2768-71
PubMed 12523141

Trondsen E, Johannessen HO, Buanes T, Raeder J (2002)
[Outpatient laparoscopic fundoplication for gastroesophageal reflux disease]
Tidsskr Nor Laegeforen, 122 (28), 2692-5
PubMed 12523086

Trondsen E, Johannessen HO, Schou CF, Buanes T (2002)
[Laparoscopic fundoplication for gastroesophageal reflux disease]
Tidsskr Nor Laegeforen, 122 (27), 2598-601
PubMed 12523186

Trondsen E, Naess PA, Erichsen A, Buanes T (2002)
[Laparoscopic treatment of splenic cysts]
Tidsskr Nor Laegeforen, 122 (9), 906-7
PubMed 12082833

Aanestad M, Røtnes JS, Edwin B, Buanes T (2002)
From operating theatre to operating studio--visualizing surgery in the age of telemedicine
J Telemed Telecare, 8 (1), 56-60; discussion 61-2
DOI 10.1258/1357633021937370, PubMed 11809087

Publications 2001

Edwin B, Mala T, Gladhaug I, Fosse E, Mathisen Y, Bergan A, Søreide O (2001)
Liver tumors and minimally invasive surgery: a feasibility study
J Laparoendosc Adv Surg Tech A, 11 (3), 133-9
DOI 10.1089/10926420152389260, PubMed 11441989

Gjertsen MK, Buanes T, Rosseland AR, Bakka A, Gladhaug I, Søreide O, Eriksen JA, Møller M, Baksaas I, Lothe RA, Saeterdal I, Gaudernack G (2001)
Intradermal ras peptide vaccination with granulocyte-macrophage colony-stimulating factor as adjuvant: Clinical and immunological responses in patients with pancreatic adenocarcinoma
Int J Cancer, 92 (3), 441-50
DOI 10.1002/ijc.1205, PubMed 11291084

Mala T, Bergan A, Edwin B, Gladhaug I, Mathisen Ø (2001)
[Liver resection--indications and results]
Tidsskr Nor Laegeforen, 121 (21), 2476-80
PubMed 11875922

Mala T, Edwin B, Samset E, Gladhaug I, Hol PK, Fosse E, Mathisen O, Bergan A, Søreide O (2001)
Magnetic-resonance-guided percutaneous cryoablation of hepatic tumours
Eur J Surg, 167 (8), 610-7
DOI 10.1080/110241501753171227, PubMed 11716448

Mala T, Frich L, Edwin B, Samset E, Hol PK, Fosse E, Mathisen Ø, Bergan A, Søreide O, Gladhaug I (2001)
[Cryoablation--a treatment option for inoperable liver tumors?]
Tidsskr Nor Laegeforen, 121 (21), 2510-5
PubMed 11875929

Mala T, Samset E, Aurdal L, Gladhaug I, Edwin B, Søreide O (2001)
Magnetic resonance imaging-estimated three-dimensional temperature distribution in liver cryolesions: a study of cryolesion characteristics assumed necessary for tumor ablation
Cryobiology, 43 (3), 268-75
DOI 10.1006/cryo.2001.2351, PubMed 11888220

Samset E, Mala T, Edwin B, Gladhaug I, Søreide O, Fosse E (2001)
Validation of estimated 3D temperature maps during hepatic cryo surgery
Magn Reson Imaging, 19 (5), 715-21
DOI 10.1016/s0730-725x(01)00389-7, PubMed 11672630

Publications 2000

Bergan A, Gladhaug IP, Schjolberg A, Bergan AB, Clausen OP (2000)
p53 accumulation confers prognostic information in resectable adenocarcinomas with ductal but not with intestinal differentiation in the pancreatic head
Int J Oncol, 17 (5), 921-6
DOI 10.3892/ijo.17.5.921, PubMed 11029493

Labori KJ, Bjørnbeth BA, Hvattum E, Lyberg T, Raeder MG (2000)
Intravenous bilirubin, dibromosulfophthalein, and bromosulfophthalein infusions uncouple biliary phospholipid and cholesterol secretion from bile acid secretion by inhibiting hepatic phosphoglycoprotein-3 activity in pigs
Scand J Gastroenterol, 35 (8), 873-82
DOI 10.1080/003655200750023264, PubMed 10994628

Publications 1999

Bjørnbeth BA, Labori KJ, Hvattum E, Lyberg T, Christensen T, Woldseth B, Raeder MG (1999)
Effect of intravenous bilirubin infusion on biliary phospholipid secretion, hepatic P-glycoprotein expression, and biliary cytotoxicity in pigs
Scand J Gastroenterol, 34 (10), 1042-9
DOI 10.1080/003655299750025165, PubMed 10563676

Publications 1998

Fiane AE, Videm V, Mellbye OJ, Foerster A, Geiran OR, Gladhaug IP, Svennevig JL, Mollnes TE (1998)
Immunoglobulin prolongs survival of pig kidneys perfused ex vivo with human blood
Scand J Immunol, 47 (6), 568-74
DOI 10.1046/j.1365-3083.1998.00341.x, PubMed 9652825

Publications 1992

Gladhaug IP, Refsnes M, Christoffersen T (1992)
Regulation of surface expression of high-affinity receptors for epidermal growth factor (EGF) in hepatocytes by hormones, differentiating agents, and phorbol ester
Dig Dis Sci, 37 (2), 233-9
DOI 10.1007/BF01308177, PubMed 1735341

Publications 1990

Gladhaug IP, Christoffersen T (1990)
Amiloride inhibits constitutive internalization and increases the surface number of epidermal growth factor receptors in intact rat hepatocytes
J Cell Physiol, 143 (1), 188-95
DOI 10.1002/jcp.1041430126, PubMed 2318906

Thoresen GH, Sand TE, Refsnes M, Dajani OF, Guren TK, Gladhaug IP, Killi A, Christoffersen T (1990)
Dual effects of glucagon and cyclic AMP on DNA synthesis in cultured rat hepatocytes: stimulatory regulation in early G1 and inhibition shortly before the S phase entry
J Cell Physiol, 144 (3), 523-30
DOI 10.1002/jcp.1041440321, PubMed 2167904

Publications 1989

Gladhaug IP, Christoffersen T (1989)
n-butyrate and dexamethasone synergistically modulate the surface expression of epidermal growth factor receptors in cultured rat hepatocytes
FEBS Lett, 243 (1), 21-4
DOI 10.1016/0014-5793(89)81209-8, PubMed 2646145

Gladhaug IP, Refsnes M, Christoffersen T (1989)
Regulation of hepatocyte epidermal growth factor receptors by n-butyrate and dimethyl sulfoxide: sensitivity to modulation by the tumor promoter TPA
Anticancer Res, 9 (6), 1587-92
PubMed 2627113

Sand TE, Gladhaug IP, Refsnes M, Christoffersen T (1989)
DNA synthesis in cultured adult rat hepatocytes: effect of serum and calcium
Liver, 9 (1), 20-6
DOI 10.1111/j.1600-0676.1989.tb00373.x, PubMed 2646505

Thoresen GH, Gjone IH, Gladhaug IP, Refsnes M, Ostby E, Christoffersen T (1989)
Studies of glucocorticoid enhancement of the capacity of hepatocytes to accumulate cyclic AMP
Pharmacol Toxicol, 65 (3), 175-80
DOI 10.1111/j.1600-0773.1989.tb01151.x, PubMed 2478993

Publications 1988

Gladhaug IP, Christoffersen T (1988)
Rapid constitutive internalization and externalization of epidermal growth factor receptors in isolated rat hepatocytes. Monensin inhibits receptor externalization and reduces the capacity for continued endocytosis of epidermal growth factor
J Biol Chem, 263 (25), 12199-203
PubMed 3261725

Gladhaug IP, Refsnes M, Sand TE, Christoffersen T (1988)
Effects of butyrate on epidermal growth factor receptor binding, morphology, and DNA synthesis in cultured rat hepatocytes
Cancer Res, 48 (22), 6560-4
PubMed 3263190

Melien O, Winsnes R, Refsnes M, Gladhaug IP, Christoffersen T (1988)
Pertussis toxin abolishes the inhibitory effects of prostaglandins E1, E2, I2 and F2 alpha on hormone-induced cAMP accumulation in cultured hepatocytes
Eur J Biochem, 172 (2), 293-7
DOI 10.1111/j.1432-1033.1988.tb13886.x, PubMed 2832160

Publications 1987

Brønstad GO, Gladhaug IP, Haffner F, Rugstad HE, Christoffersen T (1987)
The regulation of cyclic AMP levels in cultured MH1C1 rat hepatoma cells and in solid tumours derived from MH1C1 cell inoculates
Anticancer Res, 7 (2), 155-60
PubMed 3035996

Gladhaug IP, Christoffersen T (1987)
Kinetics of epidermal growth factor binding and processing in isolated intact rat hepatocytes. Dynamic externalization of receptors during ligand internalization
Eur J Biochem, 164 (2), 267-75
DOI 10.1111/j.1432-1033.1987.tb11054.x, PubMed 3494603

Publications 1986

Sandnes D, Sand TE, Sager G, Brønstad GO, Refsnes MR, Gladhaug IP, Jacobsen S, Christoffersen T (1986)
Elevated level of beta-adrenergic receptors in hepatocytes from regenerating rat liver. Time study of [125I]iodocyanopindolol binding following partial hepatectomy and its relationship to catecholamine-sensitive adenylate cyclase
Exp Cell Res, 165 (1), 117-26
DOI 10.1016/0014-4827(86)90537-9, PubMed 3011477