Publications 2024
Pancreatic duct occlusion with polychloroprene-based glue for the management of postoperative pancreatic fistula after pancreatoduodenectomy-an outdated approach?
Front Surg, 11, 1386708
DOI 10.3389/fsurg.2024.1386708, PubMed 38645504
Publications 2023
Pancreatic stellate cell-induced gemcitabine resistance in pancreatic cancer is associated with LDHA- and MCT4-mediated enhanced glycolysis
Cancer Cell Int, 23 (1), 9
DOI 10.1186/s12935-023-02852-7, PubMed 36658582
Fatty acids abrogate the growth-suppressive effects induced by inhibition of cholesterol flux in pancreatic cancer cells
Cancer Cell Int, 23 (1), 276
DOI 10.1186/s12935-023-03138-8, PubMed 37978383
Publications 2022
Neoadjuvant chemotherapy is associated with an altered metabolic profile and increased cancer stemness in patients with pancreatic ductal adenocarcinoma
Mol Oncol, 17 (1), 59-81
DOI 10.1002/1878-0261.13344, PubMed 36400567
Publications 2021
Stellate Cells Aid Growth-Permissive Metabolic Reprogramming and Promote Gemcitabine Chemoresistance in Pancreatic Cancer
Cancers (Basel), 13 (4)
DOI 10.3390/cancers13040601, PubMed 33546284
Morphological Heterogeneity in Pancreatic Cancer Reflects Structural and Functional Divergence
Cancers (Basel), 13 (4)
DOI 10.3390/cancers13040895, PubMed 33672734
Publications 2020
Establishment and Characterization of Paired Primary Cultures of Human Pancreatic Cancer Cells and Stellate Cells Derived from the Same Tumor
Cells, 9 (1)
DOI 10.3390/cells9010227, PubMed 31963309
Differential Gemcitabine Sensitivity in Primary Human Pancreatic Cancer Cells and Paired Stellate Cells Is Driven by Heterogenous Drug Uptake and Processing
Cancers (Basel), 12 (12)
DOI 10.3390/cancers12123628, PubMed 33287390
[The thesis defence is part of the doctoral degree examination]
Tidsskr Nor Laegeforen, 140 (9)
DOI 10.4045/tidsskr.20.0328, PubMed 32549008
The Thesis is part of the doctoral degree
Tidsskr. Nor. Laegeforen., 140 (9), 866-867
Is there room for a nursing science community in a medical faculty?
Tidsskr Nor Laegeforen, 140 (9)
DOI 10.4045/tidsskr.20.0311, PubMed 32549028
Is there room for a nursing science professional environment at a medical faculty?
Tidsskr. Nor. Laegeforen., 140 (9), 862-863
Publications 2019
Secretion of fibronectin by human pancreatic stellate cells promotes chemoresistance to gemcitabine in pancreatic cancer cells
BMC Cancer, 19 (1), 596
DOI 10.1186/s12885-019-5803-1, PubMed 31208372
[It is essential to fulfil the purpose of the trial lecture]
Tidsskr Nor Laegeforen, 139 (16)
DOI 10.4045/tidsskr.19.0646, PubMed 31686487
It is important that the purpose of the trial lecture is fulfilled
Tidsskr. Nor. Laegeforen., 139 (16), 1534
Clinical relevance of pancreatobiliary and intestinal subtypes of ampullary and duodenal adenocarcinoma: Pattern of recurrence, chemotherapy, and survival after pancreatoduodenectomy
Pancreatology, 19 (2), 316-324
DOI 10.1016/j.pan.2019.01.019, PubMed 30713128
Pancreatoduodenectomy with venous resection for ductal adenocarcinoma rarely achieves complete (R0) resection
HPB (Oxford), 22 (1), 50-57
DOI 10.1016/j.hpb.2019.05.005, PubMed 31186199
Commonly Used Pancreatic Stellate Cell Cultures Differ Phenotypically and in Their Interactions with Pancreatic Cancer Cells
Cells, 8 (1)
DOI 10.3390/cells8010023, PubMed 30621293
Publications 2018
Risk for hemorrhage after pancreatoduodenectomy with venous resection
Langenbecks Arch Surg, 403 (8), 949-957
DOI 10.1007/s00423-018-1721-y, PubMed 30397778
Publications 2017
Pancreatic Cancer Chemoresistance to Gemcitabine
Cancers (Basel), 9 (11)
DOI 10.3390/cancers9110157, PubMed 29144412
[Not Available]
Tidsskr Nor Laegeforen, 137 (14-15)
DOI 10.4045/tidsskr.17.0518, PubMed 28828823
Smoking, alcohol and family history of cancer as risk factors for small intestinal neuroendocrine tumors: a systematic review and meta-analysis
Scand J Gastroenterol, 52 (8), 797-802
DOI 10.1080/00365521.2017.1310290, PubMed 28394712
Portal vein reconstruction using primary anastomosis or venous interposition allograft in pancreatic surgery
J Vasc Surg Venous Lymphat Disord, 6 (1), 66-74
DOI 10.1016/j.jvsv.2017.09.003, PubMed 29128301
Trends in indications, complications and outcomes for venous resection during pancreatoduodenectomy
Br J Surg, 104 (11), 1558-1567
DOI 10.1002/bjs.10603, PubMed 28815556
Functional heterogeneity in tumor-derived human pancreatic stellate cells: Differential expression of HGF and implications for mitogenic signaling and migration in pancreatic cancer cells
Oncotarget, 8 (42), 71672-71684
DOI 10.18632/oncotarget.17800, PubMed 29069737
Publications 2016
Pathology and Surgical Treatment of High-Grade Pancreatic Neuroendocrine Carcinoma: an Evolving Landscape
Curr Oncol Rep, 18 (5), 28
DOI 10.1007/s11912-016-0518-9, PubMed 26984415
Transcriptomic Profiling of Tumor Aggressiveness in Sporadic Nonfunctioning Pancreatic Neuroendocrine Neoplasms
Pancreas, 45 (8), 1196-203
DOI 10.1097/MPA.0000000000000610, PubMed 26918873
Upregulation of INS-IGF2 read-through expression and identification of a novel INS-IGF2 splice variant in insulinomas
Oncol Rep, 36 (5), 2653-2662
DOI 10.3892/or.2016.5132, PubMed 27667266
Cold-stored cadaveric venous allograft for superior mesenteric/portal vein reconstruction during pancreatic surgery
HPB (Oxford), 18 (7), 615-22
DOI 10.1016/j.hpb.2016.05.010, PubMed 27346143
Profile of MMP and TIMP Expression in Human Pancreatic Stellate Cells: Regulation by IL-1α and TGFβ and Implications for Migration of Pancreatic Cancer Cells
Neoplasia, 18 (7), 447-56
DOI 10.1016/j.neo.2016.06.003, PubMed 27435927
The TGFβ-SMAD3 pathway inhibits IL-1α induced interactions between human pancreatic stellate cells and pancreatic carcinoma cells and restricts cancer cell migration
J Exp Clin Cancer Res, 35 (1), 122
DOI 10.1186/s13046-016-0400-5, PubMed 27473228
Dissection of Pancreatic Resection Specimens
Surg Pathol Clin, 9 (4), 523-538
DOI 10.1016/j.path.2016.05.001, PubMed 27926357
Publications 2015
Diabetes, smoking, alcohol use, and family history of cancer as risk factors for pancreatic neuroendocrine tumors: a systematic review and meta-analysis
Neuroendocrinology, 101 (2), 133-42
DOI 10.1159/000375164, PubMed 25613442
Surgical Treatment as a Principle for Patients with High-Grade Pancreatic Neuroendocrine Carcinoma: A Nordic Multicenter Comparative Study
Ann Surg Oncol, 23 (5), 1721-8
DOI 10.1245/s10434-015-5013-2, PubMed 26678407
Impact of early disease progression and surgical complications on adjuvant chemotherapy completion rates and survival in patients undergoing the surgery first approach for resectable pancreatic ductal adenocarcinoma - A population-based cohort study
Acta Oncol, 55 (3), 265-77
DOI 10.3109/0284186X.2015.1068445, PubMed 26213211
Information needs among patients and a surveillance strategy after surgery for pancreatic and periampullary cancer
HPB (Oxford), 17 (7), 659
DOI 10.1111/hpb.12411, PubMed 25776256
Increased Serum Levels of LIGHT/TNFSF14 in Nonalcoholic Fatty Liver Disease: Possible Role in Hepatic Inflammation
Clin Transl Gastroenterol, 6 (7), e95
DOI 10.1038/ctg.2015.23, PubMed 26133108
Publications 2014
Laparoscopic versus open pancreas resection for neuroendocrine tumours: need for evaluation of oncological outcomes
HPB (Oxford), 16 (9), 871
DOI 10.1111/hpb.12254, PubMed 25099232
Loss of 11p11 is a frequent and early event in sporadic nonfunctioning pancreatic neuroendocrine neoplasms
Oncol Rep, 32 (3), 906-12
DOI 10.3892/or.2014.3328, PubMed 25018013
Inhibitory effects of prostaglandin E2 on collagen synthesis and cell proliferation in human stellate cells from pancreatic head adenocarcinoma
BMC Cancer, 14, 413
DOI 10.1186/1471-2407-14-413, PubMed 24912820
COX-2 overexpression in resected pancreatic head adenocarcinomas correlates with favourable prognosis
BMC Cancer, 14, 458
DOI 10.1186/1471-2407-14-458, PubMed 24950702
The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers
Int J Cancer, 136 (4), 844-53
DOI 10.1002/ijc.29039, PubMed 24948044
Publications 2013
Liver transplantation for nonresectable liver metastases from colorectal cancer
Ann Surg, 257 (5), 800-6
DOI 10.1097/SLA.0b013e3182823957, PubMed 23360920
Pancreatic surgery with vascular reconstruction in patients with locally advanced pancreatic neuroendocrine tumors
J Gastrointest Surg, 17 (7), 1224-32
DOI 10.1007/s11605-013-2221-6, PubMed 23670519
Long-term outcome of laparoscopic surgery for pancreatic neuroendocrine tumors
World J Surg, 37 (3), 582-90
DOI 10.1007/s00268-012-1893-5, PubMed 23263686
Authors' reply: Resection margin involvement and tumour origin in pancreatic head cancer (Br J Surg 2012; 99: 1036-1049)
Br J Surg, 100 (2), 299
DOI 10.1002/bjs.9016, PubMed 23239483
Publications 2012
Surgical treatment of sporadic pancreatic neuroendocrine tumors: a state of the art review
ScientificWorldJournal, 2012, 357475
DOI 10.1100/2012/357475, PubMed 23304085
Concomitant Nonfunctional Pancreatic Neuroendocrine Tumor and Gastric GIST in a Patient Without Neurofibromatosis Type 1
J Gastrointest Cancer, 43 Suppl 1, S171-4
DOI 10.1007/s12029-011-9344-3, PubMed 22083533
Laparoscopic resection of exocrine carcinoma in central and distal pancreas results in a high rate of radical resections and long postoperative survival
Surgery, 151 (5), 717-23
DOI 10.1016/j.surg.2011.12.016, PubMed 22284762
Reclassification of tumour origin in resected periampullary adenocarcinomas reveals underestimation of distal bile duct cancer
Eur J Surg Oncol, 38 (11), 1043-50
DOI 10.1016/j.ejso.2012.07.113, PubMed 22883964
Prognostic relevance of number and ratio of metastatic lymph nodes in resected pancreatic, ampullary, and distal bile duct carcinomas
Ann Surg Oncol, 20 (1), 233-41
DOI 10.1245/s10434-012-2592-z, PubMed 22893118
Resection margin involvement and tumour origin in pancreatic head cancer
Br J Surg, 99 (8), 1036-49
DOI 10.1002/bjs.8734, PubMed 22517199
Intestinal-type and pancreatobiliary-type adenocarcinomas: how does ampullary carcinoma differ from other periampullary malignancies?
Ann Surg Oncol, 20 (2), 430-9
DOI 10.1245/s10434-012-2603-0, PubMed 22956064
Publications 2011
Fetuin A in nonalcoholic fatty liver disease: in vivo and in vitro studies
Eur J Endocrinol, 166 (3), 503-10
DOI 10.1530/EJE-11-0864, PubMed 22170794
Tumour growth is more dispersed in pancreatic head cancers than in rectal cancer: implications for resection margin assessment
Histopathology, 59 (6), 1111-21
DOI 10.1111/j.1365-2559.2011.04056.x, PubMed 22175891
Long-term follow-up of patients with resected pancreatic cancer following vaccination against mutant K-ras
Int J Cancer, 128 (5), 1120-8
DOI 10.1002/ijc.25449, PubMed 20473937
Survival estimates after pancreatoduodenectomy skewed by non-standardized histopathology reports
APMIS, 119 (10), 689-700
DOI 10.1111/j.1600-0463.2011.02783.x, PubMed 21917006
Publications 2010
Intracellular nicotinamide phosphoribosyltransferase protects against hepatocyte apoptosis and is down-regulated in nonalcoholic fatty liver disease
J Clin Endocrinol Metab, 95 (6), 3039-47
DOI 10.1210/jc.2009-2148, PubMed 20392873
Spindle proteins in resected pancreatic head adenocarcinomas: BubR1 is an independent prognostic factor in pancreatobiliary-type tumours
Histopathology, 56 (3), 345-55
DOI 10.1111/j.1365-2559.2010.03489.x, PubMed 20459534
Survival following resection of pancreatic endocrine tumors: importance of R-status and the WHO and TNM classification systems
Scand J Gastroenterol, 45 (7-8), 971-9
DOI 10.3109/00365521003782363, PubMed 20441530
Publications 2009
[Portal vein embolization before surgery for liver tumours]
Tidsskr Nor Laegeforen, 129 (1), 29-32
DOI 10.4045/tidsskr.2009.32875, PubMed 19119294
Are survival predictions reliable? Hospital volume versus standardisation of histopathologic reporting for accuracy of survival estimates after pancreatoduodenectomy for adenocarcinoma
Eur J Cancer, 45 (16), 2850-9
DOI 10.1016/j.ejca.2009.03.019, PubMed 19376696
Differentiation markers in pancreatic head adenocarcinomas: MUC1 and MUC4 expression indicates poor prognosis in pancreatobiliary differentiated tumours
Histopathology, 54 (3), 337-47
DOI 10.1111/j.1365-2559.2009.03227.x, PubMed 19236510
A complex role of activin A in non-alcoholic fatty liver disease
Am J Gastroenterol, 104 (9), 2196-205
DOI 10.1038/ajg.2009.318, PubMed 19532130
Publications 2008
[Radiofrequency ablation of colorectal liver metastases]
Tidsskr Nor Laegeforen, 128 (1), 57-60
PubMed 18183060
Nevroendokrin kreft: et informasjonshefte til pasienter og pårørende
Rikshospitalet, Oslo, 55 bl.
BIBSYS 091737575
Resectable adenocarcinomas in the pancreatic head: the retroperitoneal resection margin is an independent prognostic factor
BMC Cancer, 8, 5
DOI 10.1186/1471-2407-8-5, PubMed 18194510
Pancreatobiliary versus intestinal histologic type of differentiation is an independent prognostic factor in resected periampullary adenocarcinoma
BMC Cancer, 8, 170
DOI 10.1186/1471-2407-8-170, PubMed 18547417
Publications 2007
Local tumor progression after radiofrequency ablation of colorectal liver metastases: evaluation of ablative margin and three-dimensional volumetric analysis
J Vasc Interv Radiol, 18 (9), 1134-40
DOI 10.1016/j.jvir.2007.06.007, PubMed 17804776
Microbubbles in the pulmonary artery generated during experimental hepatic radiofrequency ablation is correlated with increased pulmonary arterial pressure
J Vasc Interv Radiol, 18 (3), 437-42
DOI 10.1016/j.jvir.2006.12.010, PubMed 17377191
Publications 2006
Increased activity of matrix metalloproteinase 2 and 9 after hepatic radiofrequency ablation
J Surg Res, 135 (2), 297-304
DOI 10.1016/j.jss.2006.05.010, PubMed 16934296
Experimental hepatic radiofrequency ablation using wet electrodes: electrode-to-vessel distance is a significant predictor for delayed portal vein thrombosis
Eur Radiol, 16 (9), 1990-9
DOI 10.1007/s00330-006-0177-6, PubMed 16541225
Hepatic radiofrequency ablation using perfusion electrodes in a pig model: effect of the Pringle manoeuvre
Eur J Surg Oncol, 32 (5), 527-32
DOI 10.1016/j.ejso.2006.02.021, PubMed 16595167
Publications 2005
Gastric perforation after percutaneous radiofrequency ablation of a colorectal liver metastasis in a patient with adhesions in the peritoneal cavity
AJR Am J Roentgenol, 184 (3 Suppl), S120-2
DOI 10.2214/ajr.184.3_supplement.0184s120, PubMed 15728002
Laparoscopic liver resection: experience of 53 procedures at a single center
J Hepatobiliary Pancreat Surg, 12 (4), 298-303
DOI 10.1007/s00534-005-0974-3, PubMed 16133696
Publications 2004
Laparoscopic resection of the pancreas: a feasibility study of the short-term outcome
Surg Endosc, 18 (3), 407-11
DOI 10.1007/s00464-003-9007-y, PubMed 14752628
Laparoscopicresection of the pancreas: a feasibility study of short-term outcome
In Surgical endoscopy, Springer International, Berlin, 18(2004)3, S. 407-11
BIBSYS 051908484
Experimental application of thermosensitive paramagnetic liposomes for monitoring magnetic resonance imaging guided thermal ablation
Magn Reson Med, 52 (6), 1302-9
DOI 10.1002/mrm.20289, PubMed 15562487
Cryoablation of colorectal liver metastases: minimally invasive tumour control
Scand J Gastroenterol, 39 (6), 571-8
DOI 10.1080/00365520410000510, PubMed 15223683
Erroneous diagnosis of pancreatic cancer after radiotherapy of testicular cancer
Eur J Surg Oncol, 30 (3), 352-5
DOI 10.1016/j.ejso.2003.09.006, PubMed 15028321
Publications 2003
Percutaneous cryoablation of colorectal liver metastases: potentiated by two consecutive freeze-thaw cycles
Cryobiology, 46 (1), 99-102
DOI 10.1016/s0011-2240(02)00163-3, PubMed 12623032
Intraoperative contrast-enhanced MR-imaging as predictor of tissue damage during cryoablation of porcine liver
Magn Reson Imaging, 21 (7), 733-40
DOI 10.1016/s0730-725x(03)00176-0, PubMed 14559337
Hepatic vascular inflow occlusion enhances tissue destruction during cryoablation of porcine liver
J Surg Res, 115 (2), 265-71
DOI 10.1016/j.jss.2003.07.009, PubMed 14697293
Publications 2002
A comparative study of the short-term outcome following open and laparoscopic liver resection of colorectal metastases
Surg Endosc, 16 (7), 1059-63
DOI 10.1007/s00464-001-9176-5, PubMed 12165823
[Laparoscopic resection of the liver]
Tidsskr Nor Laegeforen, 122 (29), 2768-71
PubMed 12523141
Publications 2001
Liver tumors and minimally invasive surgery: a feasibility study
J Laparoendosc Adv Surg Tech A, 11 (3), 133-9
DOI 10.1089/10926420152389260, PubMed 11441989
Intradermal ras peptide vaccination with granulocyte-macrophage colony-stimulating factor as adjuvant: Clinical and immunological responses in patients with pancreatic adenocarcinoma
Int J Cancer, 92 (3), 441-50
DOI 10.1002/ijc.1205, PubMed 11291084
[Liver resection--indications and results]
Tidsskr Nor Laegeforen, 121 (21), 2476-80
PubMed 11875922
Magnetic-resonance-guided percutaneous cryoablation of hepatic tumours
Eur J Surg, 167 (8), 610-7
DOI 10.1080/110241501753171227, PubMed 11716448
[Cryoablation--a treatment option for inoperable liver tumors?]
Tidsskr Nor Laegeforen, 121 (21), 2510-5
PubMed 11875929
Magnetic resonance imaging-estimated three-dimensional temperature distribution in liver cryolesions: a study of cryolesion characteristics assumed necessary for tumor ablation
Cryobiology, 43 (3), 268-75
DOI 10.1006/cryo.2001.2351, PubMed 11888220
Validation of estimated 3D temperature maps during hepatic cryo surgery
Magn Reson Imaging, 19 (5), 715-21
DOI 10.1016/s0730-725x(01)00389-7, PubMed 11672630
Publications 2000
p53 accumulation confers prognostic information in resectable adenocarcinomas with ductal but not with intestinal differentiation in the pancreatic head
Int J Oncol, 17 (5), 921-6
DOI 10.3892/ijo.17.5.921, PubMed 11029493
Publications 1998
Immunoglobulin prolongs survival of pig kidneys perfused ex vivo with human blood
Scand J Immunol, 47 (6), 568-74
DOI 10.1046/j.1365-3083.1998.00341.x, PubMed 9652825
Publications 1992
Regulation of surface expression of high-affinity receptors for epidermal growth factor (EGF) in hepatocytes by hormones, differentiating agents, and phorbol ester
Dig Dis Sci, 37 (2), 233-9
DOI 10.1007/BF01308177, PubMed 1735341
Publications 1990
Epidermal growth factor receptors in hepatocytes
Department of Pharmacology, Faculty of Medicine, University of Oslo, Oslo, 1 b. (flere pag.)
BIBSYS 900839783, ISBN 82-91012-00-8
Amiloride inhibits constitutive internalization and increases the surface number of epidermal growth factor receptors in intact rat hepatocytes
J Cell Physiol, 143 (1), 188-95
DOI 10.1002/jcp.1041430126, PubMed 2318906
Dual effects of glucagon and cyclic AMP on DNA synthesis in cultured rat hepatocytes: stimulatory regulation in early G1 and inhibition shortly before the S phase entry
J Cell Physiol, 144 (3), 523-30
DOI 10.1002/jcp.1041440321, PubMed 2167904
Publications 1989
n-butyrate and dexamethasone synergistically modulate the surface expression of epidermal growth factor receptors in cultured rat hepatocytes
FEBS Lett, 243 (1), 21-4
DOI 10.1016/0014-5793(89)81209-8, PubMed 2646145
Regulation of hepatocyte epidermal growth factor receptors by n-butyrate and dimethyl sulfoxide: sensitivity to modulation by the tumor promoter TPA
Anticancer Res, 9 (6), 1587-92
PubMed 2627113
DNA synthesis in cultured adult rat hepatocytes: effect of serum and calcium
Liver, 9 (1), 20-6
DOI 10.1111/j.1600-0676.1989.tb00373.x, PubMed 2646505
Studies of glucocorticoid enhancement of the capacity of hepatocytes to accumulate cyclic AMP
Pharmacol Toxicol, 65 (3), 175-80
DOI 10.1111/j.1600-0773.1989.tb01151.x, PubMed 2478993
Publications 1988
Rapid constitutive internalization and externalization of epidermal growth factor receptors in isolated rat hepatocytes. Monensin inhibits receptor externalization and reduces the capacity for continued endocytosis of epidermal growth factor
J Biol Chem, 263 (25), 12199-203
PubMed 3261725
Effects of butyrate on epidermal growth factor receptor binding, morphology, and DNA synthesis in cultured rat hepatocytes
Cancer Res, 48 (22), 6560-4
PubMed 3263190
Pertussis toxin abolishes the inhibitory effects of prostaglandins E1, E2, I2 and F2 alpha on hormone-induced cAMP accumulation in cultured hepatocytes
Eur J Biochem, 172 (2), 293-7
DOI 10.1111/j.1432-1033.1988.tb13886.x, PubMed 2832160
Publications 1987
The regulation of cyclic AMP levels in cultured MH1C1 rat hepatoma cells and in solid tumours derived from MH1C1 cell inoculates
Anticancer Res, 7 (2), 155-60
PubMed 3035996
Kinetics of epidermal growth factor binding and processing in isolated intact rat hepatocytes. Dynamic externalization of receptors during ligand internalization
Eur J Biochem, 164 (2), 267-75
DOI 10.1111/j.1432-1033.1987.tb11054.x, PubMed 3494603
Publications 1986
Elevated level of beta-adrenergic receptors in hepatocytes from regenerating rat liver. Time study of [125I]iodocyanopindolol binding following partial hepatectomy and its relationship to catecholamine-sensitive adenylate cyclase
Exp Cell Res, 165 (1), 117-26
DOI 10.1016/0014-4827(86)90537-9, PubMed 3011477