OUH - Research projects

Projects

CyTOheart: Cytohesins in the heart – regulation of natriuretic peptide signaling
Novel therapy for treatment-resistant hypertension
Mechanism of action of novel NPR-A activators for treatment of cardiovascular diseases
Effects of natriuretic peptides and phosphodiesterases on contractility
Natriuretic peptides and cardiac mitochondrial function

Recent publications

Andresen H, Pérez-Ternero C, Robinson J, Dickey DM, Hobbs AJ, Potter LR, Levy FO, Cataliotti A, Moltzau LR (2023)
Novel enhancers of guanylyl cyclase-A activity acting via allosteric modulation
Br J Pharmacol, 180 (24), 3254-3270
DOI 10.1111/bph.16203, PubMed 37522273

Calamera G, Moltzau LR, Levy FO, Andressen KW (2022)
Phosphodiesterases and Compartmentation of cAMP and cGMP Signaling in Regulation of Cardiac Contractility in Normal and Failing Hearts
Int J Mol Sci, 23 (4)
DOI 10.3390/ijms23042145, PubMed 35216259

Manfra O, Calamera G, Froese A, Arunthavarajah D, Surdo NC, Meier S, Melleby AO, Aasrum M, Aronsen JM, Nikolaev VO, Zaccolo M, Moltzau LR, Levy FO, Andressen KW (2022)
CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI: difference from BNP visualized by targeted cGMP biosensors
Cardiovasc Res, 118 (6), 1506-1519
DOI 10.1093/cvr/cvab167, PubMed 33970224

Get in touch

Lise Román Moltzau, Researcher, PhD
Department of Pharmacology
E-mail: l.r.moltzau@medisin.uio.no,
Tel: +47 22840217 / 98844234