Publications by Lise Román Moltzau

23 publications found

  1. Andresen H, Pérez-Ternero C, Robinson J, Dickey DM, Hobbs AJ, Potter LR, Levy FO, Cataliotti A, Moltzau LR (2023)
    Novel enhancers of guanylyl cyclase-A activity acting via allosteric modulation
    Br J Pharmacol, 180 (24), 3254-3270
    DOI 10.1111/bph.16203, PubMed 37522273
  2. Calamera G, Moltzau LR, Levy FO, Andressen KW (2022)
    Phosphodiesterases and Compartmentation of cAMP and cGMP Signaling in Regulation of Cardiac Contractility in Normal and Failing Hearts
    Int J Mol Sci, 23 (4)
    DOI 10.3390/ijms23042145, PubMed 35216259
  3. Manfra O, Calamera G, Froese A, Arunthavarajah D, Surdo NC, Meier S, Melleby AO, Aasrum M, Aronsen JM, Nikolaev VO, Zaccolo M, Moltzau LR, Levy FO, Andressen KW (2022)
    CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI: difference from BNP visualized by targeted cGMP biosensors
    Cardiovasc Res, 118 (6), 1506-1519
    DOI 10.1093/cvr/cvab167, PubMed 33970224
  4. Calamera G, Li D, Ulsund AH, Kim JJ, Neely OC, Moltzau LR, Bjørnerem M, Paterson D, Kim C, Levy FO, Andressen KW (2019)
    FRET-based cyclic GMP biosensors measure low cGMP concentrations in cardiomyocytes and neurons
    Commun Biol, 2, 394
    DOI 10.1038/s42003-019-0641-x, PubMed 31701023
  5. Cosson MV, Hiis HG, Moltzau LR, Levy FO, Krobert KA (2019)
    Knockout of adenylyl cyclase isoform 5 or 6 differentially modifies the β1-adrenoceptor-mediated inotropic response
    J Mol Cell Cardiol, 131, 132-145
    DOI 10.1016/j.yjmcc.2019.04.017, PubMed 31009605
  6. Todd Milne G, on behalf of the Ironwood team, Sandner P, Lincoln KA, Harrison PC, Chen H, Wang H, Clifford H, Qian HS, Wong D, Sarko C, Fryer R, Richman J, Reinhart GA, Boustany CM, Pullen SS, Andresen H, Moltzau LR, Cataliotti A, Levy FO, Lukowski R, Frankenreiter S, Friebe A, Calamaras T, Baumgartner R et al. (2017)
    Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017
    BMC Pharmacol Toxicol, 18 (Suppl 1), 64
    DOI 10.1186/s40360-017-0170-5, PubMed 29035170
  7. Meier S, Andressen KW, Aronsen JM, Sjaastad I, Hougen K, Skomedal T, Osnes JB, Qvigstad E, Levy FO, Moltzau LR (2017)
    PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts
    Eur J Pharmacol, 812, 174-183
    DOI 10.1016/j.ejphar.2017.07.014, PubMed 28697992
  8. Eikemo H, Moltzau LR, Nguyen CHT, Levy FO, Skomedal T, Osnes JB (2016)
    CaMKII and at least two unidentified kinases phosphorylate regulatory light chain in non-contracting cardiomyocytes
    Biochem Biophys Res Commun, 477 (1), 14-19
    DOI 10.1016/j.bbrc.2016.05.138, PubMed 27237977
  9. Eikemo H, Moltzau LR, Hussain RI, Nguyen CH, Qvigstad E, Levy FO, Skomedal T, Osnes JB (2016)
    CaMKII in addition to MLCK contributes to phosphorylation of regulatory light chain in cardiomyocytes
    Biochem Biophys Res Commun, 471 (1), 219-25
    DOI 10.1016/j.bbrc.2016.01.132, PubMed 26809094
  10. Brudeli B, Navaratnarajah M, Andressen KW, Manfra O, Moltzau LR, Nilsen NO, Levy FO, Klaveness J (2014)
    Discovery and pharmacological profile of new hydrophilic 5-HT(4) receptor antagonists
    Bioorg Med Chem Lett, 24 (18), 4598-4602
    DOI 10.1016/j.bmcl.2014.06.083, PubMed 25149506
  11. Moltzau LR, Aronsen JM, Meier S, Skogestad J, Ørstavik Ø, Lothe GB, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2014)
    Different compartmentation of responses to brain natriuretic peptide and C-type natriuretic peptide in failing rat ventricle
    J Pharmacol Exp Ther, 350 (3), 681-90
    DOI 10.1124/jpet.114.214882, PubMed 25022512
  12. Moltzau LR, Meier S, Aronsen JM, Afzal F, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2014)
    Differential regulation of C-type natriuretic peptide-induced cGMP and functional responses by PDE2 and PDE3 in failing myocardium
    Naunyn Schmiedebergs Arch Pharmacol, 387 (5), 407-17
    DOI 10.1007/s00210-013-0953-1, PubMed 24424715
  13. Brudeli B, Andressen KW, Moltzau LR, Nilsen NO, Levy FO, Klaveness J (2013)
    Acidic biphenyl derivatives: synthesis and biological activity of a new series of potent 5-HT(4) receptor antagonists
    Bioorg Med Chem, 21 (22), 7134-45
    DOI 10.1016/j.bmc.2013.09.004, PubMed 24113240
  14. Moltzau LR, Aronsen JM, Meier S, Nguyen CH, Hougen K, Ørstavik Ø, Sjaastad I, Christensen G, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2013)
    SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium
    Br J Pharmacol, 170 (2), 366-79
    DOI 10.1111/bph.12282, PubMed 23808942
  15. Brudeli B, Moltzau LR, Nguyen CH, Andressen KW, Nilsen NO, Levy FO, Klaveness J (2013)
    Synthesis and pharmacological properties of a new hydrophilic and orally bioavailable 5-HT4 antagonist
    Eur J Med Chem, 64, 629-37
    DOI 10.1016/j.ejmech.2013.03.060, PubMed 23711770
  16. Brattelid T, Qvigstad E, Moltzau LR, Bekkevold SV, Sandnes DL, Birkeland JA, Skomedal T, Osnes JB, Sjaastad I, Levy FO (2012)
    The cardiac ventricular 5-HT4 receptor is functional in late foetal development and is reactivated in heart failure
    PLoS One, 7 (9), e45489
    DOI 10.1371/journal.pone.0045489, PubMed 23029047
  17. Afzal F, Qvigstad E, Aronsen JM, Moltzau LR, Sjaastad I, Skomedal T, Osnes JB, Levy FO (2011)
    Agents increasing cyclic GMP amplify 5-HT4-elicited positive inotropic response in failing rat cardiac ventricle
    Naunyn Schmiedebergs Arch Pharmacol, 384 (6), 543-53
    DOI 10.1007/s00210-011-0670-6, PubMed 21901315
  18. Berrade L, Aisa B, Ramirez MJ, Galiano S, Guccione S, Moltzau LR, Levy FO, Nicoletti F, Battaglia G, Molinaro G, Aldana I, Monge A, Perez-Silanes S (2011)
    Novel benzo[b]thiophene derivatives as new potential antidepressants with rapid onset of action
    J Med Chem, 54 (8), 3086-90
    DOI 10.1021/jm2000773, PubMed 21469694
  19. Afzal F, Aronsen JM, Moltzau LR, Sjaastad I, Levy FO, Skomedal T, Osnes JB, Qvigstad E (2011)
    Differential regulation of β2 -adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle
    Br J Pharmacol, 162 (1), 54-71
    DOI 10.1111/j.1476-5381.2010.00890.x, PubMed 21133887
  20. Brudeli B, Moltzau LR, Andressen KW, Krobert KA, Klaveness J, Levy FO (2010)
    Synthesis and pharmacological properties of novel hydrophilic 5-HT4 receptor antagonists
    Bioorg Med Chem, 18 (24), 8600-13
    DOI 10.1016/j.bmc.2010.10.011, PubMed 21075638
  21. Qvigstad E, Moltzau LR, Aronsen JM, Nguyen CH, Hougen K, Sjaastad I, Levy FO, Skomedal T, Osnes JB (2009)
    Natriuretic peptides increase beta1-adrenoceptor signalling in failing hearts through phosphodiesterase 3 inhibition
    Cardiovasc Res, 85 (4), 763-72
    DOI 10.1093/cvr/cvp364, PubMed 19900965
  22. Kloster MM, Hafte TT, Moltzau LR, Naderi EH, Dahle MK, Skålhegg BS, Gaudernack G, Levy FO, Naderi S, Blomhoff HK (2008)
    EBV infection renders B cells resistant to growth inhibition via adenylyl cyclase
    Cell Signal, 20 (6), 1169-78
    DOI 10.1016/j.cellsig.2008.02.007, PubMed 18406106
  23. Ahamed M, Vermeulen K, Schnekenburger M, Moltzau LR, Levy FO, Marton J, Froeyen M, Olberg DE, Diederich M, Bormans G (2017)
    Synthesis, Enzyme Assays and Molecular Docking Studies of Fluorinated Bioisosteres of Santacruzamate A as Potential HDAC Tracers
    Lett. Drug Des. Discov., 14 (7), 787-797
    DOI 10.2174/1570180813666161101152943

 
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