
Christian Kranjec
- Researcher; PhD
Publications 2025
An antibiotic-free antimicrobial combination of bacteriocins and a peptidoglycan hydrolase: in vitro and in vivo assessment of its efficacy
Appl Environ Microbiol, 91 (7), e0243324
DOI 10.1128/aem.02433-24, PubMed 40552825
Publications 2024
A bacteriocin-based coating strategy to prevent vancomycin-resistant Enterococcus faecium biofilm formation on materials of interest for indwelling medical devices
Biofilm, 8, 100211
DOI 10.1016/j.bioflm.2024.100211, PubMed 39071174
Publications 2022
Bacteriocins Revitalize Non-Effective Penicillin G to Overcome Methicillin-Resistant Staphylococcus pseudintermedius
Antibiotics (Basel), 11 (12)
DOI 10.3390/antibiotics11121691, PubMed 36551348
Publications 2021
A bacteriocin-based treatment option for Staphylococcus haemolyticus biofilms
Sci Rep, 11 (1), 13909
DOI 10.1038/s41598-021-93158-z, PubMed 34230527
Staphylococcal Biofilms: Challenges and Novel Therapeutic Perspectives
Antibiotics (Basel), 10 (2)
DOI 10.3390/antibiotics10020131, PubMed 33573022
A Strong Synergy Between the Thiopeptide Bacteriocin Micrococcin P1 and Rifampicin Against MRSA in a Murine Skin Infection Model
Front Immunol, 12, 676534
DOI 10.3389/fimmu.2021.676534, PubMed 34276663
Publications 2020
A bacteriocin-based antimicrobial formulation to effectively disrupt the cell viability of methicillin-resistant Staphylococcus aureus (MRSA) biofilms
NPJ Biofilms Microbiomes, 6 (1), 58
DOI 10.1038/s41522-020-00166-4, PubMed 33268776
Successful Development of Bacteriocins into Therapeutic Formulation for Treatment of MRSA Skin Infection in a Murine Model
Antimicrob Agents Chemother, 64 (12)
DOI 10.1128/AAC.00829-20, PubMed 32958719
Publications 2019
Roles for E1-independent replication and E6-mediated p53 degradation during low-risk and high-risk human papillomavirus genome maintenance
PLoS Pathog, 15 (5), e1007755
DOI 10.1371/journal.ppat.1007755, PubMed 31083694
Publications 2017
Modulation of basal cell fate during productive and transforming HPV-16 infection is mediated by progressive E6-driven depletion of Notch
J Pathol, 242 (4), 448-462
DOI 10.1002/path.4917, PubMed 28497579
p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells
Nucleic Acids Res, 45 (19), 11056-11069
DOI 10.1093/nar/gkx721, PubMed 28977491
Publications 2016
Interaction of the Human Papillomavirus E6 Oncoprotein with Sorting Nexin 27 Modulates Endocytic Cargo Transport Pathways
PLoS Pathog, 12 (9), e1005854
DOI 10.1371/journal.ppat.1005854, PubMed 27649450
Human papillomavirus infection and induction of neoplasia: a matter of fitness
Curr Opin Virol, 20, 129-136
DOI 10.1016/j.coviro.2016.08.011, PubMed 27600900
The high-risk HPV E6 target scribble (hScrib) is required for HPV E6 expression in cervical tumour-derived cell lines
Papillomavirus Res, 2, 70-77
DOI 10.1016/j.pvr.2016.04.001, PubMed 29074188
Publications 2015
Human papillomavirus molecular biology and disease association
Rev Med Virol, 25 Suppl 1 (Suppl Suppl 1), 2-23
DOI 10.1002/rmv.1822, PubMed 25752814
HPV-16 impairs the subcellular distribution and levels of expression of protein phosphatase 1γ in cervical malignancy
BMC Cancer, 15, 230
DOI 10.1186/s12885-015-1141-0, PubMed 25886518
Publications 2014
Restoration of MAGI-1 expression in human papillomavirus-positive tumor cells induces cell growth arrest and apoptosis
J Virol, 88 (13), 7155-69
DOI 10.1128/JVI.03247-13, PubMed 24696483
Publications 2013
A novel interaction between hScrib and PP1γ downregulates ERK signaling and suppresses oncogene-induced cell transformation
PLoS One, 8 (1), e53752
DOI 10.1371/journal.pone.0053752, PubMed 23359326
Publications 2012
Human papillomaviruses and the specificity of PDZ domain targeting
FEBS J, 279 (19), 3530-3537
DOI 10.1111/j.1742-4658.2012.08709.x, PubMed 22805590
Publications 2011
Stabilization of HPV16 E6 protein by PDZ proteins, and potential implications for genome maintenance
Virology, 414 (2), 137-45
DOI 10.1016/j.virol.2011.03.017, PubMed 21489588
PDZ domains: the building blocks regulating tumorigenesis
Biochem J, 439 (2), 195-205
DOI 10.1042/BJ20110903, PubMed 21954943
Analysis of the PDZ binding specificities of Influenza A virus NS1 proteins
Virol J, 8, 25
DOI 10.1186/1743-422X-8-25, PubMed 21247458
Publications 2010
A systematic analysis of human papillomavirus (HPV) E6 PDZ substrates identifies MAGI-1 as a major target of HPV type 16 (HPV-16) and HPV-18 whose loss accompanies disruption of tight junctions
J Virol, 85 (4), 1757-64
DOI 10.1128/JVI.01756-10, PubMed 21123374
The mechanism and implications of hScrib regulation of ERK
Small GTPases, 1 (2), 108-112
DOI 10.4161/sgtp.1.2.13649, PubMed 21686263