Institute Seminar Wednesday, June 2nd, 12 o’clock, on Zoom: Helene Knævelsrud, Department of Molecular Cell Biology
Title of her talk:
When should you stop eating yourself? Termination of autophagy from fruit flies to cancer cells
Place: on Zoom
When should you stop eating yourself? Termination of autophagy from fruit flies to cancer cells
Abstract:
Cells in a living organism need to be able to readily respond to changes in nutritional status. Upon starvation, certain tissues respond by activating autophagy to provide energy and building blocks necessary to sustain essential cellular functions. Importantly, these cells must also turn off autophagy when nutrient supplies are replenished, or as an adaptation to prolonged starvation, because unrestricted autophagy is harmful to the fitness of the organism. Surprisingly little is known about how autophagy is terminated. Therefore, our team is focused on understanding the mechanisms and regulation of this process. We study termination of autophagy in vivo in fruit flies, and findings there have also brought us to further investigations in kidney cancer.
Links:
Helene Knævelsrud's project group:
Mapping and disrupting cancer circuits
Helene Knævelsrud's publications
Institute seminar overview spring season 2021
On behalf of the organizing commitee 2021:
Anette Weyergang
Tord Hompland
Helga B. Landsverk
Department of Radiation Biology