Llorente/Sandvig publish potential biomarkers for prostate cancer
Llorente (left) and Sandvig
Alicia Llorente and Kirsten Sandvig, Department of Biochemistry, Institute for Cancer Research and Centre for Cancer Biomedicine, have recently published in Molecular and Cellular Proteomics (impact factor 8.4) a proteomic analysis of microvesicles released from a human prostate cancer cell line. Most of the 266 proteins identified have previously been reported to be present in vesicles released from other cell types, but several proteins seem to be specific for prostate cancer cells. Since microvesicles can reach biological fluids, these proteins are thus potentially useful as new non invasive biomarkers for detection, diagnosis and/or prognosis of prostate cancer.
From major journals, first or last author from the Institute for Cancer Research
Høyvik AJK, Stenberg VY, Liukaityte R, Repetto-Llamazares A, Peng Q, Wangen-Riise R, Wiig E, Ma LW, Revheim ME, Juzeniene A(2025) Optimizing [212Pb]Pb-AB001 Radiopharmaceutical Therapy Schedules in PSMA-Positive Subcutaneous Prostate Cancer Xenografts J Nucl Med(in press) DOI 10.2967/jnumed.125.270444, PubMed 41043994
Pharo H, Vedeld HM, Wahlqvist R, Lind GE(2025) Re: Thomas Dreyer, Simone Brandt, Knud Fabrin, et al. Use of the Xpert Bladder Cancer Monitor Urinary Biomarker Test for Guiding Cystoscopy in High-grade Non-muscle-invasive Bladder Cancer: Results from the Randomized Controlled DaBlaCa-15 Trial. Eur Urol 2025;88:23-30 Eur Urol(in press) DOI 10.1016/j.eururo.2025.07.028, PubMed 40998632
Pfefferle A, Malmberg KJ(2025) Rewiring natural killer cells for next-generation cancer therapies Cancer Cell(in press) DOI 10.1016/j.ccell.2025.08.007, PubMed 40972573
Emaldi M, Rey-Iborra E, Alamillo-Maeso P, Pulido R, Nunes-Xavier CE(2026) Analysis of the Functional Impact of Glycosylation on Immune Checkpoint Proteins Methods Mol Biol, 2959, 55-72 DOI 10.1007/978-1-0716-4734-9_4, PubMed 41028258
Rey-Iborra E, Emaldi M, Madariaga M, Pulido R, Nunes-Xavier CE(2026) 3D Spheroids to Study the Impact of Immune Checkpoint Proteins in Solid Tumors Methods Mol Biol, 2959, 141-156 DOI 10.1007/978-1-0716-4734-9_10, PubMed 41028264
Laura Szekeres, Zobolas J(2025) PyDrugLogics: A Python Package for Predicting Drug Synergies Using Boolean Models Journal of Open Source Software, 10(114), 8038 DOI 10.21105/joss.08038, PublikaID 548