Otto A. Smiseth
- Professor Emeritus and former Head of Division of Cardiovascular and Pulmonary Diseases; MD, PhD
- +47 230 73271
Otto A. Smiseth, MD, PhD, FESC, FACC, FASE
Current position: Professor Emeritus and Senior Associate Editor, EHJ-Cardiovascular Imaging.
Otto A. Smiseth earned his MD from University of Oslo 1975 and a PhD in Medicine at Tromsø University 1983, as well as a Master of Health Administration in 1994. He was a Visiting Research fellow at University of California, San Francisco, USA in 1981, and a Visiting Postdoctoral Research fellow at University of Calgary, Alberta, Canada during 1982-84.
He is a specialist in internal medicine from 1989 and in cardiology from 1991, and has worked as a Resident at Ullevål, Aker Sykehus and Rikshospitalet. He has also been a consultant cardiologist at Aker Sykehus.
He became Professor II at the University of Oslo in 1995. From 2001 he has functioned as the Head of the Department of Cardiology, Rikshospitalet, and in 2005 he became the Head of the Heart and Lung Clinic, Rikshospitalet. From 2009 he has functioned as the Head of Division of Cardiovascular and Pulmonary Diseases.
Otto Smiseth has had a number of positions in both Norwegian and International Medicine, this includes among others Head of The Norwegian Research Council Clinical Research Grant Committee, Head of the Grant committee of the Norwegian Council on Cardiovascular Diseases, President of the Nordic Congress of Cardiology, Member of the Board of the European Society of Cardiology (ESC), Secretary and Treasurer of the Board of the ESC and currently Chairman of the Education Committee in the ESC. He is also a member of editorial boards for several international journals.
He has published approximately 160 scientific articles, mainly in leading internationals journals and has guided 15 fellows for the academic doctor degree. He also collaborates with several national and international research groups.
Publications 2024
Left atrial reservoir strain in prognosis of heart failure and time for getting terminology straight
Eur Heart J Cardiovasc Imaging, 25 (3), 325-327
DOI 10.1093/ehjci/jead311, PubMed 37966264
Echocardiographic Evaluation of Left Ventricular Filling Pressure in Patients With Pulmonary Hypertension
JACC Cardiovasc Imaging, 17 (5), 566-567
DOI 10.1016/j.jcmg.2023.12.004, PubMed 38340138
Left atrium as key player and essential biomarker in heart failure
J Cardiol (in press)
DOI 10.1016/j.jjcc.2024.07.006, PubMed 39084316
Evaluation of left ventricular filling pressure by echocardiography in patients with atrial fibrillation
Echo Res Pract, 11 (1), 14
DOI 10.1186/s44156-024-00048-x, PubMed 38825684
How to Conduct Clinical Research in Cardiovascular Imaging: A Primer for Clinical Cardiologists and Researchers. A Statement of the European Association of Cardiovascular Imaging (EACVI) of the ESC
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeae238, PubMed 39226295
Association between myocardial work indices and cardiovascular events according to hypertension in the general population
Eur Heart J Cardiovasc Imaging, 25 (3), 413-424
DOI 10.1093/ehjci/jead292, PubMed 37930752
Improving post-MI risk stratification with pressure-strain loops: Work in progress
Int J Cardiol, 402, 131866
DOI 10.1016/j.ijcard.2024.131866, PubMed 38382855
Mechanical dyssynchrony as a selection criterion for cardiac resynchronization therapy: Design of the AMEND-CRT trial
ESC Heart Fail (in press)
DOI 10.1002/ehf2.14932, PubMed 38984947
Non-invasive myocardial work in aortic stenosis: validation and improvement in left ventricular pressure estimation
Eur Heart J Cardiovasc Imaging, 25 (2), 201-212
DOI 10.1093/ehjci/jead227, PubMed 37672652
The assessment of left ventricular diastolic function: guidance and recommendations from the British Society of Echocardiography
Echo Res Pract, 11 (1), 16
DOI 10.1186/s44156-024-00051-2, PubMed 38825710
What Is the Current Best Drug Treatment for Hypertensive Heart Failure With Preserved Ejection Fraction? Review of the Totality of Evidence
Am J Hypertens, 37 (1), 1-14
DOI 10.1093/ajh/hpad073, PubMed 37551929
Left atrial volume as risk marker: Is minimum volume superior to maximum volume?
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeae136, PubMed 38781443
Focus issue on heart failure with preserved left ventricular ejection fraction
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeae211, PubMed 39150253
Estimating left atrial pressure in atrial fibrillation: An ongoing struggle
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeae195, PubMed 39074211
Myocardial Strain Imaging: Theory, Current Practice, and the Future
JACC Cardiovasc Imaging (in press)
DOI 10.1016/j.jcmg.2024.07.011, PubMed 39269417
Left ventricular diastolic dysfunction in non-myocardial disorders
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeae209, PubMed 39172598
Publications 2023
Echocardiographic Evaluation of Diastolic Function in Special Populations
Am J Cardiol, 202, 131-143
DOI 10.1016/j.amjcard.2023.05.032, PubMed 37429061
Mechanical Dyssynchrony Combined with Septal Scarring Reliably Identifies Responders to Cardiac Resynchronization Therapy
J Clin Med, 12 (18)
DOI 10.3390/jcm12186108, PubMed 37763048
Cardiac Magnetic Resonance Identifies Responders to Cardiac Resynchronization Therapy with an Assessment of Septal Scar and Left Ventricular Dyssynchrony
J Clin Med, 12 (22)
DOI 10.3390/jcm12227182, PubMed 38002795
Machine learning in diastolic dysfunction: Left atrial strain trace superior to single points for estimation of filling pressure†
Eur Heart J Cardiovasc Imaging, 25 (1), 27-28
DOI 10.1093/ehjci/jead257, PubMed 37818845
The current best drug treatment for hypertensive heart failure with preserved ejection fraction
Eur J Intern Med, 120, 3-10
DOI 10.1016/j.ejim.2023.10.008, PubMed 37865559
Mental Stress Reduces Left Ventricular Strain: Can It Lead to Misinterpretation of Cancer Therapy-Related Cardiac Dysfunction?
J Am Soc Echocardiogr, 37 (5), 564-566
DOI 10.1016/j.echo.2023.11.010, PubMed 37981246
Trouble with estimating filling pressure in acute heart failure: lessons from Takotsubo syndrome
Eur Heart J Cardiovasc Imaging, 24 (6), 708-709
DOI 10.1093/ehjci/jead082, PubMed 37185785
Phenotyping heart failure by echocardiography: imaging of ventricular function and haemodynamics at rest and exercise
Eur Heart J Cardiovasc Imaging, 24 (10), 1329-1342
DOI 10.1093/ehjci/jead196, PubMed 37542477
The challenge of understanding heart failure with supernormal left ventricular ejection fraction: time for building the patient's 'digital twin'
Eur Heart J Cardiovasc Imaging, 24 (3), 301-303
DOI 10.1093/ehjci/jeac268, PubMed 36637135
Personality traits and cardiovascular diseases: is it about 'don't worry, be happy', or is this a deeper underlying problem?
Eur Heart J Cardiovasc Imaging, 24 (11), 1468-1469
DOI 10.1093/ehjci/jead185, PubMed 37523776
Cardiovascular imaging in personalized medicine: focus issue on phenotyping heart failure
Eur Heart J Cardiovasc Imaging, 24 (10), 1281-1282
DOI 10.1093/ehjci/jead183, PubMed 37530463
Imaging in patients with cardiovascular implantable electronic devices: part 1-imaging before and during device implantation. A clinical consensus statement of the European Association of Cardiovascular Imaging (EACVI) and the European Heart Rhythm Association (EHRA) of the ESC
Eur Heart J Cardiovasc Imaging, 25 (1), e1-e32
DOI 10.1093/ehjci/jead272, PubMed 37861372
Imaging in patients with cardiovascular implantable electronic devices: part 2-imaging after device implantation. A clinical consensus statement of the European Association of Cardiovascular Imaging (EACVI) and the European Heart Rhythm Association (EHRA) of the ESC
Eur Heart J Cardiovasc Imaging, 25 (1), e33-e54
DOI 10.1093/ehjci/jead273, PubMed 37861420
Publications 2022
Left atrial strain imaging: ready for clinical implementation in heart failure with preserved ejection fraction
Eur Heart J Cardiovasc Imaging, 23 (9), 1169-1170
DOI 10.1093/ehjci/jeac059, PubMed 35383851
Visual Presence of Mechanical Dyssynchrony Combined With Septal Scarring Identifies Responders to Cardiac Resynchronization Therapy
JACC Cardiovasc Imaging, 15 (12), 2151-2153
DOI 10.1016/j.jcmg.2022.06.020, PubMed 36481085
Left atrial strain is a predictor of left ventricular systolic and diastolic reverse remodelling in CRT candidates
Eur Heart J Cardiovasc Imaging, 23 (10), 1373-1382
DOI 10.1093/ehjci/jeab163, PubMed 34432006
Derek G. Gibson-a unique scientist and cardiologist, 1936-2021
Eur Heart J Cardiovasc Imaging, 23 (5), 600
DOI 10.1093/ehjci/jeac024, PubMed 35137007
Increased deformation of the left ventricle during exercise test measured by global longitudinal strain can rule out significant coronary artery disease in patients with suspected unstable angina pectoris
Echocardiography, 39 (2), 233-239
DOI 10.1111/echo.15295, PubMed 35043455
Scar imaging in the dyssynchronous left ventricle: Accuracy of myocardial metabolism by positron emission tomography and function by echocardiographic strain
Int J Cardiol, 372, 122-129
DOI 10.1016/j.ijcard.2022.11.042, PubMed 36460211
Myocardial Work in Patients Hospitalized With COVID-19: Relation to Biomarkers, COVID-19 Severity, and All-Cause Mortality
J Am Heart Assoc, 11 (19), e026571
DOI 10.1161/JAHA.122.026571, PubMed 36129046
Normal Values for Myocardial Work Indices Derived From Pressure-Strain Loop Analyses: From the CCHS
Circ Cardiovasc Imaging, 15 (5), e013712
DOI 10.1161/CIRCIMAGING.121.013712, PubMed 35535593
How to assess left ventricular filling pressures by echocardiography in clinical practice
Eur Heart J Cardiovasc Imaging, 23 (9), 1127-1129
DOI 10.1093/ehjci/jeac123, PubMed 35762650
Order of tricuspid and mitral valve opening as an index of left ventricular filling pressure and prognosis
Eur Heart J Cardiovasc Imaging, 23 (5), 627-628
DOI 10.1093/ehjci/jeab239, PubMed 34791146
Left ventricular performance by work and wasted energy: is strain not sufficient?
Eur Heart J Cardiovasc Imaging, 23 (2), 198-199
DOI 10.1093/ehjci/jeab233, PubMed 34739071
The challenge of assessing left ventricular function after repair of aortic coarctation: Can we do better?
Rev Port Cardiol, 41 (4), 309-310
DOI 10.1016/j.repc.2021.12.005, PubMed 36062663
Multimodality imaging in patients with heart failure and preserved ejection fraction: an expert consensus document of the European Association of Cardiovascular Imaging
Eur Heart J Cardiovasc Imaging, 23 (2), e34-e61
DOI 10.1093/ehjci/jeab154, PubMed 34729586
Publications 2021
Left ventricular regional glucose metabolism in combination with septal scar extent identifies CRT responders
Eur J Nucl Med Mol Imaging, 48 (8), 2437-2446
DOI 10.1007/s00259-020-05161-7, PubMed 33416956
Echocardiographic view and feature selection for the estimation of the response to CRT
PLoS One, 16 (6), e0252857
DOI 10.1371/journal.pone.0252857, PubMed 34111154
Importance of Systematic Right Ventricular Assessment in Cardiac Resynchronization Therapy Candidates: A Machine Learning Approach
J Am Soc Echocardiogr, 34 (5), 494-502
DOI 10.1016/j.echo.2020.12.025, PubMed 33422667
Prognostic utility of the assessment of diastolic function in patients undergoing cardiac resynchronization therapy
Int J Cardiol, 331, 144-151
DOI 10.1016/j.ijcard.2021.01.046, PubMed 33535079
Left ventricular strain for predicting the response to cardiac resynchronization therapy: two methods for one question
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeaa422, PubMed 33517397
Determinants of left atrial reservoir and pump strain and use of atrial strain for evaluation of left ventricular filling pressure
Eur Heart J Cardiovasc Imaging, 23 (1), 61-70
DOI 10.1093/ehjci/jeaa415, PubMed 33496314
Corrigendum to: Determinants of left atrial reservoir and pump strain and use of atrial strain for evaluation of left ventricular filling pressure
Eur Heart J Cardiovasc Imaging, 23 (1), 136
DOI 10.1093/ehjci/jeab194, PubMed 34608485
Hypertension and heart failure with preserved ejection fraction: position paper by the European Society of Hypertension
J Hypertens, 39 (8), 1522-1545
DOI 10.1097/HJH.0000000000002910, PubMed 34102660
Why mechanical dyssynchrony remains relevant to cardiac resynchronization therapy. Letter regarding the article 'Optimized implementation of cardiac resynchronization therapy: a call for action for referral and optimization of care: a joint position statement from the Heart Failure Association (HFA), European Heart Rhythm Association (EHRA), and European Association of Cardiovascular Imaging (EACVI) of the European Society of Cardiology'
Eur J Heart Fail, 23 (5), 843-844
DOI 10.1002/ejhf.2150, PubMed 33704878
Lateral Wall Dysfunction Signals Onset of Progressive Heart Failure in Left Bundle Branch Block
JACC Cardiovasc Imaging, 14 (11), 2059-2069
DOI 10.1016/j.jcmg.2021.04.017, PubMed 34147454
Imaging of the left atrium: pathophysiology insights and clinical utility
Eur Heart J Cardiovasc Imaging, 23 (1), 2-13
DOI 10.1093/ehjci/jeab191, PubMed 34601594
How to measure left ventricular myocardial work by pressure-strain loops
Eur Heart J Cardiovasc Imaging, 22 (3), 259-261
DOI 10.1093/ehjci/jeaa301, PubMed 33257982
Focus on the left atrium in cardiac disease
Eur Heart J Cardiovasc Imaging, 23 (1), 1
DOI 10.1093/ehjci/jeab259, PubMed 34871359
Right ventricular work: a step forward for non-invasive assessment of right ventricular function
Eur Heart J Cardiovasc Imaging, 22 (2), 153-154
DOI 10.1093/ehjci/jeaa296, PubMed 33279985
Heart failure and systolic function: time to leave diagnostics based on ejection fraction?
Eur Heart J, 42 (7), 786-788
DOI 10.1093/eurheartj/ehaa979, PubMed 33454774
Strain identifies pseudo-normalized right ventricular function in tricuspid regurgitation
Eur Heart J Cardiovasc Imaging, 22 (8), 876-877
DOI 10.1093/ehjci/jeab089, PubMed 34148090
Publications 2020
Left bundle branch block increases left ventricular diastolic pressure during tachycardia due to incomplete relaxation
J Appl Physiol (1985), 128 (4), 729-738
DOI 10.1152/japplphysiol.01002.2018, PubMed 31999529
Acute redistribution of regional left ventricular work by cardiac resynchronization therapy determines long-term remodelling
Eur Heart J Cardiovasc Imaging, 21 (6), 619-628
DOI 10.1093/ehjci/jeaa003, PubMed 32031587
Prediction of response to cardiac resynchronization therapy using a multi-feature learning method
Int J Cardiovasc Imaging, 37 (3), 989-998
DOI 10.1007/s10554-020-02083-1, PubMed 33226549
Regional myocardial work by cardiac magnetic resonance and non-invasive left ventricular pressure: a feasibility study in left bundle branch block
Eur Heart J Cardiovasc Imaging, 21 (2), 143-153
DOI 10.1093/ehjci/jez231, PubMed 31599327
The left atrium: a mirror of ventricular systolic and diastolic function
Eur Heart J Cardiovasc Imaging, 21 (3), 270-272
DOI 10.1093/ehjci/jez305, PubMed 31840753
Finding the "Golden Moment" for TAVR: Look Below the Valve
JACC Cardiovasc Imaging, 13 (12), 2573-2575
DOI 10.1016/j.jcmg.2020.08.018, PubMed 33129727
Mechanical Effects on Right Ventricular Function From Left Bundle Branch Block and Cardiac Resynchronization Therapy
JACC Cardiovasc Imaging, 13 (7), 1475-1484
DOI 10.1016/j.jcmg.2019.11.016, PubMed 31954643
Imaging predictors of response to cardiac resynchronization therapy: left ventricular work asymmetry by echocardiography and septal viability by cardiac magnetic resonance
Eur Heart J, 41 (39), 3813-3823
DOI 10.1093/eurheartj/ehaa603, PubMed 32918449
Publications 2019
Myocardial work by echocardiography: a novel method ready for clinical testing
Eur Heart J Cardiovasc Imaging, 20 (1), 18-20
DOI 10.1093/ehjci/jey156, PubMed 30376059
Left ventricular end-systolic volume is a more sensitive marker of acute response to cardiac resynchronization therapy than contractility indices: insights from an experimental study
Europace, 21 (2), 347-355
DOI 10.1093/europace/euy221, PubMed 30418572
Myocardial constructive work and cardiac mortality in resynchronization therapy candidates
Am Heart J, 212, 53-63
DOI 10.1016/j.ahj.2019.02.008, PubMed 30951976
Diastolic Stress Test: Invasive and Noninvasive Testing
JACC Cardiovasc Imaging, 13 (1 Pt 2), 272-282
DOI 10.1016/j.jcmg.2019.01.037, PubMed 31202741
Global longitudinal strain is a more reproducible measure of left ventricular function than ejection fraction regardless of echocardiographic training
Cardiovasc Ultrasound, 17 (1), 18
DOI 10.1186/s12947-019-0168-9, PubMed 31477137
Medical Therapies for Heart Failure With Preserved Ejection Fraction
Hypertension, 75 (1), 23-32
DOI 10.1161/HYPERTENSIONAHA.119.14057, PubMed 31786973
Interobserver Variability in Applying American Society of Echocardiography/European Association of Cardiovascular Imaging 2016 Guidelines for Estimation of Left Ventricular Filling Pressure
Circ Cardiovasc Imaging, 12 (1), e008122
DOI 10.1161/CIRCIMAGING.118.008122, PubMed 30632389
The Authors Reply
JACC Cardiovasc Imaging, 12 (10), 2097-2098
DOI 10.1016/j.jcmg.2019.08.006, PubMed 31601383
Heart Failure with normal ejection fraction
Tidsskr. Nor. Laegeforen., 139 (6), 522-527
[Heart failure with preserved ejection fraction]
Tidsskr Nor Laegeforen, 139 (6)
DOI 10.4045/tidsskr.18.0523, PubMed 30917641
Myocardial Efficiency: A Fundamental Physiological Concept on the Verge of Clinical Impact
JACC Cardiovasc Imaging, 13 (7), 1564-1576
DOI 10.1016/j.jcmg.2019.08.030, PubMed 31864979
Mechanism of Abnormal Septal Motion in Left Bundle Branch Block: Role of Left Ventricular Wall Interactions and Myocardial Scar
JACC Cardiovasc Imaging, 12 (12), 2402-2413
DOI 10.1016/j.jcmg.2018.11.030, PubMed 30772230
Editorial commentary: Septal flash - what is behind the flashy name?
Trends Cardiovasc Med, 30 (2), 123-124
DOI 10.1016/j.tcm.2019.04.003, PubMed 31010721
Publications 2018
Evaluation of diastolic function by echocardiography: important progression, but issues to be resolved
Eur Heart J Cardiovasc Imaging, 19 (4), 387-388
DOI 10.1093/ehjci/jex319, PubMed 29236972
Role of myocardial constructive work in the identification of responders to CRT
Eur Heart J Cardiovasc Imaging, 19 (9), 1010-1018
DOI 10.1093/ehjci/jex191, PubMed 28954293
Mean Right Atrial Pressure for Estimation of Left Ventricular Filling Pressure in Patients with Normal Left Ventricular Ejection Fraction: Invasive and Noninvasive Validation
J Am Soc Echocardiogr, 31 (7), 799-806
DOI 10.1016/j.echo.2018.01.025, PubMed 29580694
Need for better diastolic stress test: twistin' time is here?
Eur Heart J Cardiovasc Imaging, 19 (1), 20-22
DOI 10.1093/ehjci/jex307, PubMed 29161382
Mechanism of harm from left bundle branch block
Trends Cardiovasc Med, 29 (6), 335-342
DOI 10.1016/j.tcm.2018.10.012, PubMed 30401603
Reply: Interaction Between Longitudinal, Circumferential, and Radial Deformations and Their Contributions to Ejection Fraction
J Am Coll Cardiol, 71 (2), 257-258
DOI 10.1016/j.jacc.2017.10.090, PubMed 29325649
Reply: Left Ventricular Twist: An Often Ignored But Crucial Determinant of Left Ventricular Function
J Am Coll Cardiol, 71 (5), 584-585
DOI 10.1016/j.jacc.2017.12.002, PubMed 29406870
Dysfunction of the systemic right ventricle after atrial switch: physiological implications of altered septal geometry and load
J Appl Physiol (1985), 125 (5), 1482-1489
DOI 10.1152/japplphysiol.00255.2018, PubMed 30188795
Afterload Hypersensitivity in Patients With Left Bundle Branch Block
JACC Cardiovasc Imaging, 12 (6), 967-977
DOI 10.1016/j.jcmg.2017.11.025, PubMed 29361486
Publications 2017
Estimating Left Ventricular Filling Pressure by Echocardiography
J Am Coll Cardiol, 69 (15), 1937-1948
DOI 10.1016/j.jacc.2017.01.058, PubMed 28408024
Reply: Issues With Estimating "Diastolic Function" and Left Ventricular Filling Pressure Using the New Guidelines
J Am Coll Cardiol, 70 (9), 1198-1199
DOI 10.1016/j.jacc.2017.05.073, PubMed 28838373
Intra-Aortic Balloon Pump Optimizes Myocardial Function During Cardiogenic Shock
JACC Cardiovasc Imaging, 11 (3), 512-514
DOI 10.1016/j.jcmg.2017.05.019, PubMed 28823741
Value of Myocardial Work Estimation in the Prediction of Response to Cardiac Resynchronization Therapy
J Am Soc Echocardiogr, 31 (2), 220-230
DOI 10.1016/j.echo.2017.10.009, PubMed 29246513
Mechanical dyssynchrony-resurrected as a flashing and rocking parameter to predict prognosis after cardiac resynchronization therapy
Eur Heart J Cardiovasc Imaging, 18 (10), 1118-1119
DOI 10.1093/ehjci/jex198, PubMed 28984891
Evaluation of left ventricular diastolic function: state of the art after 35 years with Doppler assessment
J Echocardiogr, 16 (2), 55-64
DOI 10.1007/s12574-017-0364-2, PubMed 29236226
Letter by Smiseth and Nagueh et al Regarding Article, "Role of Diastolic Stress Testing in the Evaluation for Heart Failure With Preserved Ejection Fraction: A Simultaneous Invasive-Echocardiographic Study"
Circulation, 136 (4), 428-429
DOI 10.1161/CIRCULATIONAHA.117.027881, PubMed 28739815
Geometry as a Confounder When Assessing Ventricular Systolic Function: Comparison Between Ejection Fraction and Strain
J Am Coll Cardiol, 70 (8), 942-954
DOI 10.1016/j.jacc.2017.06.046, PubMed 28818204
Publications 2016
The Authors Reply
JACC Cardiovasc Imaging, 9 (6), 758-9
DOI 10.1016/j.jcmg.2015.11.015, PubMed 26897672
Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging
Eur Heart J Cardiovasc Imaging, 17 (12), 1321-1360
DOI 10.1093/ehjci/jew082, PubMed 27422899
Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging
J Am Soc Echocardiogr, 29 (4), 277-314
DOI 10.1016/j.echo.2016.01.011, PubMed 27037982
Exhausted atrial reserve by tissue Doppler echocardiography: a risk marker in heart failure with reduced ejection fraction
Eur Heart J Cardiovasc Imaging, 17 (7), 732-4
DOI 10.1093/ehjci/jew090, PubMed 27145800
Wasted septal work in left ventricular dyssynchrony: a novel principle to predict response to cardiac resynchronization therapy
Eur Heart J Cardiovasc Imaging, 17 (6), 624-32
DOI 10.1093/ehjci/jew019, PubMed 26921169
Publications 2015
Non-invasive myocardial work index identifies acute coronary occlusion in patients with non-ST-segment elevation-acute coronary syndrome
Eur Heart J Cardiovasc Imaging, 16 (11), 1247-55
DOI 10.1093/ehjci/jev078, PubMed 25851329
Pathophysiological rationale and diagnostic targets for diastolic stress testing
Heart, 101 (17), 1355-60
DOI 10.1136/heartjnl-2014-307040, PubMed 26001845
Assessment of regional myocardial work in rats
Circ Cardiovasc Imaging, 8 (2), e002695
DOI 10.1161/CIRCIMAGING.114.002695, PubMed 25673647
Cardiac Imaging to Evaluate Left Ventricular Diastolic Function
JACC Cardiovasc Imaging, 8 (9), 1071-1093
DOI 10.1016/j.jcmg.2015.07.004, PubMed 26381769
Cardiac Mechanical Alterations and Genotype Specific Differences in Subjects With Long QT Syndrome
JACC Cardiovasc Imaging, 8 (5), 501-510
DOI 10.1016/j.jcmg.2014.12.023, PubMed 25890583
Strain, strain rate, torsion, and twist: echocardiographic evaluation
Curr Cardiol Rep, 17 (3), 568
DOI 10.1007/s11886-015-0568-x, PubMed 25676830
Factors determining the magnitude of the pre-ejection leftward septal motion in left bundle branch block
Europace, 18 (12), 1905-1913
DOI 10.1093/europace/euv381, PubMed 26612883
Strain echocardiographic assessment of left atrial function predicts recurrence of atrial fibrillation
Eur Heart J Cardiovasc Imaging, 17 (6), 660-7
DOI 10.1093/ehjci/jev185, PubMed 26219297
Pulmonary veins: an important side window into ventricular function
Eur Heart J Cardiovasc Imaging, 16 (11), 1189-90
DOI 10.1093/ehjci/jev149, PubMed 26104961
Myocardial strain imaging: how useful is it in clinical decision making?
Eur Heart J, 37 (15), 1196-207
DOI 10.1093/eurheartj/ehv529, PubMed 26508168
Publications 2014
Cardiac responses to left ventricular pacing in hearts with normal electrical conduction: beneficial effect of improved filling is counteracted by dyssynchrony
Am J Physiol Heart Circ Physiol, 307 (3), H370-8
DOI 10.1152/ajpheart.00089.2014, PubMed 24906920
European Association of Cardiovascular Imaging (EACVI) position paper: Multimodality imaging in pericardial disease
Eur Heart J Cardiovasc Imaging, 16 (1), 12-31
DOI 10.1093/ehjci/jeu128, PubMed 25248336
Early assessment of strain echocardiography can accurately exclude significant coronary artery stenosis in suspected non-ST-segment elevation acute coronary syndrome
J Am Soc Echocardiogr, 27 (5), 512-9
DOI 10.1016/j.echo.2014.01.019, PubMed 24612899
A systematic review of diastolic stress tests in heart failure with preserved ejection fraction, with proposals from the EU-FP7 MEDIA study group
Eur J Heart Fail, 16 (12), 1345-61
DOI 10.1002/ejhf.184, PubMed 25393338
Left ventricular global longitudinal strain is associated with exercise capacity in failing hearts with preserved and reduced ejection fraction
Eur Heart J Cardiovasc Imaging, 16 (2), 217-24
DOI 10.1093/ehjci/jeu277, PubMed 25552469
New strategies for heart failure with preserved ejection fraction: the importance of targeted therapies for heart failure phenotypes
Eur Heart J, 35 (40), 2797-815
DOI 10.1093/eurheartj/ehu204, PubMed 25104786
Publications 2013
Altered maternal left ventricular contractility and function during normal pregnancy
Ultrasound Obstet Gynecol, 41 (6), 659-66
DOI 10.1002/uog.12296, PubMed 23001841
Increased arterial stiffness in pre-eclamptic pregnancy at term and early and late postpartum: a combined echocardiographic and tonometric study
Am J Hypertens, 26 (4), 549-56
DOI 10.1093/ajh/hps067, PubMed 23467210
ESC core curriculum for the general cardiologist (2013)
Eur Heart J, 34 (30), 2381-411
DOI 10.1093/eurheartj/eht234, PubMed 23847131
Strain echocardiography improves risk prediction of ventricular arrhythmias after myocardial infarction
JACC Cardiovasc Imaging, 6 (8), 841-50
DOI 10.1016/j.jcmg.2013.03.005, PubMed 23850251
Assessment of wasted myocardial work: a novel method to quantify energy loss due to uncoordinated left ventricular contractions
Am J Physiol Heart Circ Physiol, 305 (7), H996-1003
DOI 10.1152/ajpheart.00191.2013, PubMed 23893165
Cardioprotection during chemotherapy: need for faster transfer of knowledge from cardiology to oncology and role for a cardio-oncologist
J Am Coll Cardiol, 61 (23), 2363-4
DOI 10.1016/j.jacc.2013.02.073, PubMed 23583243
Publications 2012
Systemic arterial response and ventriculo-arterial interaction during normal pregnancy
Am J Hypertens, 25 (6), 672-7
DOI 10.1038/ajh.2012.29, PubMed 22460202
Myocardial relaxation, restoring forces, and early-diastolic load are independent determinants of left ventricular untwisting rate
Circulation, 126 (12), 1441-51
DOI 10.1161/CIRCULATIONAHA.111.080861, PubMed 22865889
A novel clinical method for quantification of regional left ventricular pressure-strain loop area: a non-invasive index of myocardial work
Eur Heart J, 33 (6), 724-33
DOI 10.1093/eurheartj/ehs016, PubMed 22315346
Duration of myocardial early systolic lengthening predicts the presence of significant coronary artery disease
J Am Coll Cardiol, 60 (12), 1086-93
DOI 10.1016/j.jacc.2012.06.022, PubMed 22939559
Identification of viable myocardium in acute anterior infarction using duration of systolic lengthening by tissue Doppler strain: a preliminary study
J Am Soc Echocardiogr, 25 (7), 718-25
DOI 10.1016/j.echo.2012.04.016, PubMed 22622107
Cardiomyocyte-restricted inhibition of G protein-coupled receptor kinase-3 attenuates cardiac dysfunction after chronic pressure overload
Am J Physiol Heart Circ Physiol, 303 (1), H66-74
DOI 10.1152/ajpheart.00724.2011, PubMed 22542621
Publications 2011
Postsystolic shortening is a strong predictor of recovery of systolic function in patients with non-ST-elevation myocardial infarction
Eur J Echocardiogr, 12 (7), 483-9
DOI 10.1093/ejechocard/jer055, PubMed 21609975
Mechanisms of abnormal systolic motion of the interventricular septum during left bundle-branch block
Circ Cardiovasc Imaging, 4 (3), 264-73
DOI 10.1161/CIRCIMAGING.110.961417, PubMed 21393502
Mean strain throughout the heart cycle by longitudinal two-dimensional speckle-tracking echocardiography enables early prediction of infarct size
J Am Soc Echocardiogr, 24 (10), 1118-25
DOI 10.1016/j.echo.2011.06.002, PubMed 21764553
Current and evolving echocardiographic techniques for the quantitative evaluation of cardiac mechanics: ASE/EAE consensus statement on methodology and indications endorsed by the Japanese Society of Echocardiography
J Am Soc Echocardiogr, 24 (3), 277-313
DOI 10.1016/j.echo.2011.01.015, PubMed 21338865
Current and evolving echocardiographic techniques for the quantitative evaluation of cardiac mechanics: ASE/EAE consensus statement on methodology and indications endorsed by the Japanese Society of Echocardiography
Eur J Echocardiogr, 12 (3), 167-205
DOI 10.1093/ejechocard/jer021, PubMed 21385887
Doppler Classification of Diastolic Dysfunction Reply
J. Am. Soc. Echocardiogr., 24 (8), 932-933
DOI 10.1016/j.echo.2011.05.019
Echocardiographic evaluation of hemodynamics in patients with decompensated systolic heart failure
Circ Cardiovasc Imaging, 4 (3), 220-7
DOI 10.1161/CIRCIMAGING.111.963496, PubMed 21398512
Mechanics of left ventricular relaxation, early diastolic lengthening, and suction investigated in a mathematical model
Am J Physiol Heart Circ Physiol, 300 (5), H1678-87
DOI 10.1152/ajpheart.00165.2010, PubMed 21317306
Mechanism of prolonged electromechanical delay in late activated myocardium during left bundle branch block
Am J Physiol Heart Circ Physiol, 301 (6), H2334-43
DOI 10.1152/ajpheart.00644.2011, PubMed 21984549
Right ventricular mechanical dispersion is related to malignant arrhythmias: a study of patients with arrhythmogenic right ventricular cardiomyopathy and subclinical right ventricular dysfunction
Eur Heart J, 32 (9), 1089-96
DOI 10.1093/eurheartj/ehr069, PubMed 21406439
The advantage of global strain compared to left ventricular ejection fraction to predict outcome after acute myocardial infarction
Echocardiography, 28 (5), 556-63
DOI 10.1111/j.1540-8175.2011.01384.x, PubMed 21535118
The role of echocardiography in quantification of left ventricular dyssynchrony: state of the art and future directions
Eur Heart J Cardiovasc Imaging, 13 (1), 61-8
DOI 10.1093/ejechocard/jer243, PubMed 22094237
Publications 2010
Strain echocardiography and wall motion score index predicts final infarct size in patients with non-ST-segment-elevation myocardial infarction
Circ Cardiovasc Imaging, 3 (2), 187-94
DOI 10.1161/CIRCIMAGING.109.910521, PubMed 20075142
Strain echocardiography predicts acute coronary occlusion in patients with non-ST-segment elevation acute coronary syndrome
Eur J Echocardiogr, 11 (6), 501-8
DOI 10.1093/ejechocard/jeq008, PubMed 20185525
Acute coronary occlusion in non-ST-elevation acute coronary syndrome: outcome and early identification by strain echocardiography
Heart, 96 (19), 1550-6
DOI 10.1136/hrt.2009.188391, PubMed 20643662
Changes of myocardial function in patients with non-ST-elevation acute coronary syndrome awaiting coronary angiography
Am J Cardiol, 105 (9), 1212-8
DOI 10.1016/j.amjcard.2009.12.036, PubMed 20403468
Transmural differences in myocardial contraction in long-QT syndrome: mechanical consequences of ion channel dysfunction
Circulation, 122 (14), 1355-63
DOI 10.1161/CIRCULATIONAHA.110.960377, PubMed 20855658
Mechanical dispersion assessed by myocardial strain in patients after myocardial infarction for risk prediction of ventricular arrhythmia
JACC Cardiovasc Imaging, 3 (3), 247-56
DOI 10.1016/j.jcmg.2009.11.012, PubMed 20223421
Comments on point: Counterpoint: Left ventricular volume during diastasis is/is not the physiological in vivo equilibrium volume and is/is not related to diastolic suction
J Appl Physiol (1985), 109 (2), 612
DOI 10.1152/japplphysiol.00558.2010, PubMed 21312417
Evaluation of left ventricular dyssynchrony by onset of active myocardial force generation: a novel method that differentiates between electrical and mechanical etiologies
Circ Cardiovasc Imaging, 3 (4), 405-14
DOI 10.1161/CIRCIMAGING.109.905539, PubMed 20494943
Spotlight: Otto Smiseth, MD, PhD, FESC, FACC
Circulation, 122 (4), F22-F23
Team 2010: Integrated Cardiovascular Function, Oslo University Hospital, Oslo, Norway
Circulation, 122 (4), F24
Publications 2009
Abnormal left ventricular relaxation in patients with long QT syndrome: reply
Eur. Heart J., 30 (22), 2814-2815
DOI 10.1093/eurheartj/ehp445
Clinical assessment of left ventricular rotation and strain: a novel approach for quantification of function in infarcted myocardium and its border zones
Am J Physiol Heart Circ Physiol, 297 (1), H257-67
DOI 10.1152/ajpheart.01116.2008, PubMed 19395547
A novel echocardiographic marker of end systole in the ischemic left ventricle: "tug of war" sign
Am J Physiol Heart Circ Physiol, 296 (3), H645-54
DOI 10.1152/ajpheart.00313.2008, PubMed 19122168
Recommendations for the evaluation of left ventricular diastolic function by echocardiography
Eur J Echocardiogr, 10 (2), 165-93
DOI 10.1093/ejechocard/jep007, PubMed 19270053
Recommendations for the evaluation of left ventricular diastolic function by echocardiography
J Am Soc Echocardiogr, 22 (2), 107-33
DOI 10.1016/j.echo.2008.11.023, PubMed 19187853
Determinants of left ventricular early-diastolic lengthening velocity: independent contributions from left ventricular relaxation, restoring forces, and lengthening load
Circulation, 119 (19), 2578-86
DOI 10.1161/CIRCULATIONAHA.108.791681, PubMed 19414640
Ventricular function in patients with transposition of the great arteries operated with arterial switch
Am J Cardiol, 104 (4), 583-9
DOI 10.1016/j.amjcard.2009.04.029, PubMed 19660616
Response to Letter Regarding Article, "Mechanisms of Preejection and Postejection Velocity Spikes in Left Ventricular Myocardium: Interaction Between Wall Deformation and Valve Events"
Circulation, 119 (6), E205
DOI 10.1161/CIRCULATIONAHA.108.823716
Comparison of left ventricular ejection fraction and left ventricular global strain as determinants of infarct size in patients with acute myocardial infarction
J Am Soc Echocardiogr, 22 (11), 1232-8
DOI 10.1016/j.echo.2009.07.027, PubMed 19815383
Pacing in heart failure patients with narrow QRS: is there more to gain than resynchronization?
Circulation, 120 (17), 1651-3
DOI 10.1161/CIRCULATIONAHA.109.900381, PubMed 19822804
Publications 2008
Left ventricular mechanical dispersion by tissue Doppler imaging: a novel approach for identifying high-risk individuals with long QT syndrome
Eur Heart J, 30 (3), 330-7
DOI 10.1093/eurheartj/ehn466, PubMed 18940888
Apical rotation by speckle tracking echocardiography: a simplified bedside index of left ventricular twist
J Am Soc Echocardiogr, 21 (10), 1121-8
DOI 10.1016/j.echo.2008.06.012, PubMed 18760568
Mechanisms of preejection and postejection velocity spikes in left ventricular myocardium: interaction between wall deformation and valve events
Circulation, 118 (4), 373-80
DOI 10.1161/CIRCULATIONAHA.107.748491, PubMed 18606917
Publications 2007
Eksperimentell kardiovaskulær forskning
In Det Norske hjerte: norsk hjertemedisins historie, Universitetsforl., Oslo, S. 283-292
BIBSYS 070830584
How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology: reply
Eur. Heart J., 28 (21), 2686-2687
DOI 10.1093/eurheartj/ehm380
How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology
Eur Heart J, 28 (20), 2539-50
DOI 10.1093/eurheartj/ehm037, PubMed 17428822
Contraction pattern of the systemic right ventricle shift from longitudinal to circumferential shortening and absent global ventricular torsion
J Am Coll Cardiol, 49 (25), 2450-6
DOI 10.1016/j.jacc.2007.02.062, PubMed 17599609
Left ventricular function in patients with transposition of the great arteries operated with atrial switch
Pediatr Cardiol, 29 (3), 597-603
DOI 10.1007/s00246-007-9156-1, PubMed 18040733
Characteristic strain pattern of moderately ischemic myocardium investigated in a finite element simulation model
LECT NOTES COMPUT SC, 4466, 330-+
Cardiac-restricted expression of the carboxyl-terminal fragment of GRK3 Uncovers Distinct Functions of GRK3 in regulation of cardiac contractility and growth: GRK3 controls cardiac alpha1-adrenergic receptor responsiveness
J Biol Chem, 283 (16), 10601-10
DOI 10.1074/jbc.M708912200, PubMed 18165681
Publications 2006
Noninvasive myocardial strain measurement by speckle tracking echocardiography: validation against sonomicrometry and tagged magnetic resonance imaging
J Am Coll Cardiol, 47 (4), 789-93
DOI 10.1016/j.jacc.2005.10.040, PubMed 16487846
Hjertetransplantasjon i Norge: festskrift til Svein Simonsen på hans 70-års dag
Hjertemedisinsk avd., Rikshospitalet, [Oslo], 125 s.
BIBSYS 060292989
Systolic dysfunction in heart failure with normal ejection fraction: speckle-tracking echocardiography
Prog Cardiovasc Dis, 49 (3), 207-14
DOI 10.1016/j.pcad.2006.08.008, PubMed 17084180
Grading of myocardial dysfunction by tissue Doppler echocardiography: a comparison between velocity, displacement, and strain imaging in acute ischemia
J Am Coll Cardiol, 47 (8), 1672-82
DOI 10.1016/j.jacc.2006.01.051, PubMed 16631008
Infections in surgical intensive care medicine and 30 years of research on organ failure and organ protection: written in tribute to prof. Ansgar O. Aasen on the occasion of his 60th birthday in 2005
Institute for Surgical Research, Rikshospitalet, Oslo, 224 s.
BIBSYS 07051058x
Publications 2005
New noninvasive method for assessment of left ventricular rotation: speckle tracking echocardiography
Circulation, 112 (20), 3149-56
DOI 10.1161/CIRCULATIONAHA.104.531558, PubMed 16286606
Deceleration time of systolic pulmonary venous flow: a new clinical marker of left atrial pressure and compliance
J Appl Physiol (1985), 100 (2), 685-9
DOI 10.1152/japplphysiol.00705.2005, PubMed 16239613
Myocardial acceleration during isovolumic contraction: relationship to contractility
Circulation, 111 (11), 1362-9
DOI 10.1161/01.CIR.0000158432.86860.A6, PubMed 15753217
Myocardial strain analysis in acute coronary occlusion: a tool to assess myocardial viability and reperfusion
Circulation, 112 (25), 3901-10
DOI 10.1161/CIRCULATIONAHA.105.533372, PubMed 16365210
Executive summary of the guidelines on the diagnosis and treatment of acute heart failure: the Task Force on Acute Heart Failure of the European Society of Cardiology
Eur Heart J, 26 (4), 384-416
DOI 10.1093/eurheartj/ehi044, PubMed 15681577
Regional left ventricular electric and mechanical activation and relaxation
J Am Coll Cardiol, 47 (1), 173-4
DOI 10.1016/j.jacc.2005.10.039, PubMed 16386682
The task force for the diagnosis and treatment of chronic heart failure of the european society of cardiology: Guidelines for the diagnosis and treatment of chronic heart failure: Reply
Eur. Heart J., 26 (22), 2473-2474
DOI 10.1093/eurheartj/ehi551
[Diagnosis and treatment of chronic heart disease. Guidelines of the European Society of Cardiology. Revision 2005]
Kardiol Pol, 63 (5), 509-43; discussion 544-8
PubMed 16362857
[Guidelines for the Diagnosis and Treatment of Chronic Heart Failure: executive summary (update 2005)]
Rev Esp Cardiol, 58 (9), 1062-92
DOI 10.1157/13078554, PubMed 16185619
Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology
Eur Heart J, 26 (11), 1115-40
DOI 10.1093/eurheartj/ehi204, PubMed 15901669
Regional myocardial work by strain Doppler echocardiography and LV pressure: a new method for quantifying myocardial function
Am J Physiol Heart Circ Physiol, 288 (5), H2375-80
DOI 10.1152/ajpheart.00946.2004, PubMed 15637114
Publications 2004
Guidelines on management (diagnosis and treatment) of syncope-update 2004. Executive Summary
Eur Heart J, 25 (22), 2054-72
DOI 10.1016/j.ehj.2004.09.004, PubMed 15541843
Guidelines on diagnosis and treatment of pulmonary arterial hypertension. The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of Cardiology
Eur Heart J, 25 (24), 2243-78
DOI 10.1016/j.ehj.2004.09.014, PubMed 15589643
Guidelines on prevention, diagnosis and treatment of infective endocarditis executive summary; the task force on infective endocarditis of the European society of cardiology
Eur Heart J, 25 (3), 267-76
DOI 10.1016/j.ehj.2003.11.008, PubMed 14972429
[Expert Consensus document on angiotensin converting enzyme inhibitors in cardiovascular disease]
Rev Esp Cardiol, 57 (12), 1213-32
DOI 10.1157/13069868, PubMed 15617645
Expert consensus document on the use of antiplatelet agents. The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European society of cardiology
Eur Heart J, 25 (2), 166-81
DOI 10.1016/j.ehj.2003.10.013, PubMed 14720534
An ultrasound-based method for determining pulse wave velocity in superficial arteries
J Biomech, 37 (10), 1615-22
DOI 10.1016/j.jbiomech.2003.12.031, PubMed 15336937
Development of an in vivo method for determining material properties of passive myocardium
Model. Identif. Control, 25 (4), 237-252
DOI 10.4173/mic.2004.4.3
Development of an in vivo method for determining material properties of passive myocardium
J Biomech, 37 (5), 669-78
DOI 10.1016/j.jbiomech.2003.09.023, PubMed 15046996
News from the European Society of Cardiology congress in Vienna, August 30 to September 3, 2003
J Am Coll Cardiol, 43 (4), 691-7
DOI 10.1016/j.jacc.2003.11.025, PubMed 14975484
Tissue Doppler imaging for the diagnosis of coronary artery disease
Curr Opin Cardiol, 19 (5), 421-9
DOI 10.1097/01.hco.0000135672.79534.e9, PubMed 15316447
Mechanisms of elevated plasma endothelin-1 in CHF: congestion increases pulmonary synthesis and secretion of endothelin-1
Cardiovasc Res, 63 (1), 41-50
DOI 10.1016/j.cardiores.2004.03.016, PubMed 15194460
Publications 2003
ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias--executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Supraventricular Arrhythmias)
Circulation, 108 (15), 1871-909
DOI 10.1161/01.CIR.0000091380.04100.84, PubMed 14557344
ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias--executive summary. a report of the American college of cardiology/American heart association task force on practice guidelines and the European society of cardiology committee for practice guidelines (writing committee to develop guidelines for the management of patients with supraventricular arrhythmias) developed in collaboration with NASPE-Heart Rhythm Society
J Am Coll Cardiol, 42 (8), 1493-531
DOI 10.1016/j.jacc.2003.08.013, PubMed 14563598
Management of grown up congenital heart disease
Eur Heart J, 24 (11), 1035-84
DOI 10.1016/s0195-668x(03)00131-3, PubMed 12868424
Strain rate imaging: why do we need it?
J Am Coll Cardiol, 42 (9), 1584-6
DOI 10.1016/j.jacc.2003.08.005, PubMed 14607442
Postsystolic shortening of ischemic myocardium: a mechanism of abnormal intraventricular filling
Am J Physiol Heart Circ Physiol, 284 (6), H2343-50
DOI 10.1152/ajpheart.00320.2002, PubMed 12574003
Publications 2002
Quantitative assessment of intrinsic regional myocardial deformation by Doppler strain rate echocardiography in humans: validation against three-dimensional tagged magnetic resonance imaging
Circulation, 106 (1), 50-6
DOI 10.1161/01.cir.0000019907.77526.75, PubMed 12093769
Quantification of left ventricular systolic function by tissue Doppler echocardiography: added value of measuring pre- and postejection velocities in ischemic myocardium
Circulation, 105 (17), 2071-7
DOI 10.1161/01.cir.0000014614.63980.ba, PubMed 11980687
Effects of acute volume loading and hemorrhage on intestinal vascular capacitance: a mechanism whereby capacitance modulates cardiac output
Can J Cardiol, 18 (5), 515-22
PubMed 12032578
Postsystolic shortening in ischemic myocardium: active contraction or passive recoil?
Circulation, 106 (6), 718-24
DOI 10.1161/01.cir.0000024102.55150.b6, PubMed 12163433
Mechanisms of diastolic intraventricular regional pressure differences and flow in the inflow and outflow tracts
J Am Coll Cardiol, 40 (5), 983-90
DOI 10.1016/s0735-1097(02)02046-6, PubMed 12225727
Quantification of left ventricular diastolic pressure-volume relations during routine cardiac catheterization by two-dimensional digital echo quantification and left ventricular micromanometer
J Am Soc Echocardiogr, 15 (3), 225-32
DOI 10.1067/mje.2002.118174, PubMed 11875385
Publications 2001
High frame rate Doppler echocardiography in the rat: an evaluation of the method
Eur J Echocardiogr, 2 (2), 78-87
DOI 10.1053/euje.2000.0050, PubMed 11911099
Assessment of ventricular diastolic function
Can J Cardiol, 17 (11), 1167-76
PubMed 11726985
[PET--already a useful clinical tool]
Tidsskr Nor Laegeforen, 121 (9), 1156
PubMed 11354902
Publications 2000
Acute regional myocardial ischemia identified by 2-dimensional multiregion tissue Doppler imaging technique
J Am Soc Echocardiogr, 13 (11), 986-94
DOI 10.1067/mje.2000.108466, PubMed 11093100
Methods for assessing hepatic distending pressure and changes in hepatic capacitance in pigs
Am J Physiol Heart Circ Physiol, 279 (4), H1796-803
DOI 10.1152/ajpheart.2000.279.4.H1796, PubMed 11009466
Regulation of ET: pulmonary release of ET contributes to increased plasma ET levels and vasoconstriction in CHF
Am J Physiol Heart Circ Physiol, 278 (4), H1299-310
DOI 10.1152/ajpheart.2000.278.4.H1299, PubMed 10749728
Positronemisjonstomografi (PET) - diagnostisk og klinisk nytteverdi: metodevurdering basert på internasjonal og egen litteraturgransking
In SMM-rapport, Senteret, Oslo, nr 8/2000, 47 s.
BIBSYS 010081003, ISBN 82-14-02180-4
Atrioventricular filling dynamics, diastolic function and dysfunction
Heart Fail Rev, 5 (4), 291-9
DOI 10.1023/a:1026531511226, PubMed 11498642
Myocardial strain by Doppler echocardiography. Validation of a new method to quantify regional myocardial function
Circulation, 102 (10), 1158-64
DOI 10.1161/01.cir.102.10.1158, PubMed 10973846
Publications 1999
Mechanism of pulmonary venous pressure and flow waves
Heart Vessels, 14 (2), 67-71
DOI 10.1007/BF02481745, PubMed 10651182
Diastolic flow pattern in the normal left ventricle
J Am Soc Echocardiogr, 12 (6), 500-7
DOI 10.1016/s0894-7317(99)70087-8, PubMed 10359922
The pulmonary venous systolic flow pulse--its origin and relationship to left atrial pressure
J Am Coll Cardiol, 34 (3), 802-9
DOI 10.1016/s0735-1097(99)00300-9, PubMed 10483963
Mechanisms of retarded apical filling in acute ischemic left ventricular failure
Circulation, 99 (15), 2048-54
DOI 10.1161/01.cir.99.15.2048, PubMed 10209011
Publications 1998
ET-receptor antagonism, myocardial gene expression, and ventricular remodeling during CHF in rats
Am J Physiol, 275 (3), H868-77
DOI 10.1152/ajpheart.1998.275.3.H868, PubMed 9724291
Hepatic oxygen metabolism in porcine endotoxemia: the effect of nitric oxide synthase inhibition
Am J Physiol, 275 (6), G1377-85
DOI 10.1152/ajpgi.1998.275.6.G1377, PubMed 9843775
Mechanics of intraventricular filling: study of LV early diastolic pressure gradients and flow velocities
Am J Physiol, 275 (3), H1062-9
DOI 10.1152/ajpheart.1998.275.3.H1062, PubMed 9724314
Early diastolic intraventricular filling pattern in acute myocardial infarction by color M-mode Doppler echocardiography
J Am Soc Echocardiogr, 11 (2), 119-25
DOI 10.1016/s0894-7317(98)70069-0, PubMed 9517550
Publications 1997
Regulation of hepatic vascular volume: contributions from active and passive mechanisms during catecholamine and sodium nitroprusside infusion
Circulation, 96 (12), 4415-23
DOI 10.1161/01.cir.96.12.4415, PubMed 9416912
Transient, isopeptide-specific induction of myocardial endothelin-1 mRNA in congestive heart failure in rats
Am J Physiol, 273 (4), H1727-36
DOI 10.1152/ajpheart.1997.273.4.H1727, PubMed 9362237
Increased cardiac expression of endothelin-1 mRNA in ischemic heart failure in rats
Cardiovasc Res, 33 (3), 601-10
DOI 10.1016/s0008-6363(96)00266-0, PubMed 9093530
Publications 1996
[Cardiology education in Norway--does it keep up with the needs?]
Tidsskr Nor Laegeforen, 116 (8), 976-80
PubMed 8650661
The NO donor sodium nitroprusside reverses the negative effects on hepatic arterial flow induced by endotoxin and the NO synthase inhibitor L-NAME
Eur Surg Res, 28 (5), 323-32
DOI 10.1159/000129473, PubMed 8880121
Hypertensive left ventricular hypertrophy: pathophysiology, assessment and treatment
Blood Press, 5 (1), 5-15
DOI 10.3109/08037059609062101, PubMed 8777473
Nitric oxide synthase inhibition reduces venous return in porcine endotoxemia
Am J Physiol, 271 (4 Pt 2), H1325-32
DOI 10.1152/ajpheart.1996.271.4.H1325, PubMed 8897924
[Can heart failure be diagnosed by hormone tests?]
Tidsskr Nor Laegeforen, 116 (13), 1560-1
PubMed 8685864
[Physicians' view on drug therapy for hypertension. A questionnaire in the county of Hordaland]
Tidsskr Nor Laegeforen, 116 (13), 1588-90
PubMed 8685872
A potential clinical method for calculating transmural left ventricular filling pressure during positive end-expiratory pressure ventilation: an intraoperative study in humans
J Am Coll Cardiol, 27 (1), 155-60
DOI 10.1016/0735-1097(95)00420-3, PubMed 8522690
Publications 1995
Measurement of intestinal vascular capacitance in dogs: an application of blood pool scintigraphy
J Appl Physiol (1985), 78 (1), 232-8
DOI 10.1152/jappl.1995.78.1.232, PubMed 7713818
Intraventricular early diastolic velocity profile during acute myocardial ischemia: a color M-mode Doppler echocardiographic study
J Am Soc Echocardiogr, 8 (3), 270-9
DOI 10.1016/s0894-7317(05)80037-9, PubMed 7640020
Splanchnic venous pressure-volume relation during experimental acute ischemic heart failure. Differential effects of hydralazine, enalaprilat, and nitroglycerin
Circulation, 91 (4), 1205-12
DOI 10.1161/01.cir.91.4.1205, PubMed 7850960
Publications 1994
Effect of enalaprilat on splanchnic vascular capacitance during acute ischemic heart failure in dogs
Am J Physiol, 266 (6 Pt 2), H2182-9
DOI 10.1152/ajpheart.1994.266.6.H2182, PubMed 8023980
Effect of carotid sinus baroreceptor reflex on hepatic and splenic vascular capacitance in vagotomized dogs
Am J Physiol, 266 (4 Pt 2), H1528-33
DOI 10.1152/ajpheart.1994.266.4.H1528, PubMed 8184930
Juxtacardiac pleural pressure during positive end-expiratory pressure ventilation: an intraoperative study in patients with open pericardium
J Am Coll Cardiol, 23 (3), 753-8
DOI 10.1016/0735-1097(94)90764-1, PubMed 8113561
Repeatability of colour M-mode Doppler measurements of left ventricular filling
Int J Cardiol, 43 (1), 79-85
DOI 10.1016/0167-5273(94)90094-9, PubMed 8175223
Influence of heart rate and left atrial pressure on pulmonary venous flow pattern in dogs
Am J Physiol, 266 (6 Pt 2), H2296-302
DOI 10.1152/ajpheart.1994.266.6.H2296, PubMed 8023990
Intracavitary filling pattern in the failing left ventricle assessed by color M-mode Doppler echocardiography
J Am Coll Cardiol, 24 (3), 663-70
DOI 10.1016/0735-1097(94)90012-4, PubMed 8077536
Visual assessment of intra ventricular flow from colour M-mode Doppler images
Int J Card Imaging, 10 (4), 279-87
DOI 10.1007/BF01137719, PubMed 7722349
Selective positive end-expiratory pressure and right ventricular function in dogs
Acta Anaesthesiol Scand, 38 (2), 175-9
DOI 10.1111/j.1399-6576.1994.tb03862.x, PubMed 8171954
Publications 1993
[Lipid-lowering medication--indications and possible hazards. Report from a hearing]
Tidsskr Nor Laegeforen, 113 (23), 2930-2
PubMed 8236199
[The requirement to use the cheapest synonymous preparation--does it work as intended?]
Tidsskr Nor Laegeforen, 113 (29), 3582-5
PubMed 8273099
Effect of nifedipine on splanchnic and pulmonary vascular capacitance
Clin Physiol, 13 (3), 247-55
DOI 10.1111/j.1475-097x.1993.tb00324.x, PubMed 8519160
Changes in pulmonary vein flow pattern during volume loading
Cardiovasc Res, 27 (3), 411-5
DOI 10.1093/cvr/27.3.411, PubMed 8490940
Intraventricular early diastolic filling during acute myocardial ischemia, assessment by multigated color m-mode Doppler echocardiography
Circulation, 88 (6), 2705-13
DOI 10.1161/01.cir.88.6.2705, PubMed 8252682
Publications 1992
Patency of the internal mammary artery used as sequential graft
Scand J Thorac Cardiovasc Surg, 26 (1), 57-9
DOI 10.3109/14017439209099053, PubMed 1529298
Effect of the pericardium on atrial systolic function
J Appl Physiol (1985), 73 (4), 1360-5
DOI 10.1152/jappl.1992.73.4.1360, PubMed 1447080
Nitroprusside and regional vascular capacitance in patients with severe congestive heart failure
Circulation, 85 (3), 997-1002
DOI 10.1161/01.cir.85.3.997, PubMed 1537136
Haemodynamic effects of selective positive end-expiratory pressure after unilateral pulmonary hydrochloric acid-aspiration in dogs
Intensive Care Med, 18 (6), 356-61
DOI 10.1007/BF01694364, PubMed 1469162
Selective positive end-expiratory pressure and intracardiac dimensions in dogs
J Appl Physiol (1985), 73 (5), 2016-20
DOI 10.1152/jappl.1992.73.5.2016, PubMed 1474080
Publications 1991
The relationship between atrial pressure, atrial dimensions and atrial natriuretic factor during pacing tachycardia in dogs
Acta Anaesthesiol Scand, 35 (8), 731-5
DOI 10.1111/j.1399-6576.1991.tb03380.x, PubMed 1837197
Rate-induced increase in plasma atrial natriuretic factor can occur independently of changes in atrial wall stretch
Am J Physiol, 260 (6 Pt 2), H1953-8
DOI 10.1152/ajpheart.1991.260.6.H1953, PubMed 1829336
Endocrine responses to positive end-expiratory pressure ventilation in patients who have recently undergone heart surgery
Acta Anaesthesiol Scand, 35 (3), 242-6
DOI 10.1111/j.1399-6576.1991.tb03281.x, PubMed 2038932
The effect of positive end-expiratory pressure ventilation on atrial filling
Acta Anaesthesiol Scand, 35 (5), 448-52
DOI 10.1111/j.1399-6576.1991.tb03326.x, PubMed 1887748
Blood volume changes in liver and spleen during cardiogenic shock in dogs
Am J Physiol, 261 (6 Pt 2), H1763-8
DOI 10.1152/ajpheart.1991.261.6.H1763, PubMed 1750533
Splanchnic vascular capacitance and positive end-expiratory pressure in dogs
J Appl Physiol (1985), 70 (2), 818-24
DOI 10.1152/jappl.1991.70.2.818, PubMed 2022573
Left and right ventricular diastolic function during acute pericardial tamponade
Clin Physiol, 11 (1), 61-71
DOI 10.1111/j.1475-097x.1991.tb00654.x, PubMed 2019079
The effect of nitroglycerin on pulmonary vascular capacitance in dogs
Am Heart J, 121 (5), 1454-9
DOI 10.1016/0002-8703(91)90152-8, PubMed 1902053
Publications 1990
[Drug therapy of acute coronary syndrome. Summary of a hearing arranged by the Norwegian Cardiologic Society and the Institute of pharmacotherapy]
Tidsskr Nor Laegeforen, 110 (21), 2788-90
PubMed 1977207
The dependence of the time constant of left ventricular isovolumic relaxation (tau) on pericardial pressure
Circulation, 81 (3), 1071-80
DOI 10.1161/01.cir.81.3.1071, PubMed 2306816
A randomized study of SMS 201-995 versus bromocriptine treatment in acromegaly: clinical and biochemical effects
J Clin Endocrinol Metab, 70 (5), 1254-61
DOI 10.1210/jcem-70-5-1254, PubMed 2186055
Effect of intracoronary contrast medium on left ventricular diastolic pressure-volume relationships
Am Heart J, 119 (1), 59-63
DOI 10.1016/s0002-8703(05)80082-1, PubMed 2296875
Assessment of left ventricular relaxation by Doppler echocardiography. Comparison of isovolumic relaxation time and transmitral flow velocities with time constant of isovolumic relaxation
Circulation, 81 (1), 260-6
DOI 10.1161/01.cir.81.1.260, PubMed 2297830
Left ventricular filling at elevated diastolic pressures: relationship between transmitral Doppler flow velocities and atrial contribution
Am Heart J, 119 (3 Pt 1), 620-6
DOI 10.1016/s0002-8703(05)80285-6, PubMed 2309604
Assessment of the splanchnic vascular capacity and capacitance using quantitative equilibrium blood-pool scintigraphy
J Nucl Med, 31 (2), 154-9
PubMed 2156027
A comparison of changes in esophageal pressure and regional juxtacardiac pressures
J Appl Physiol (1985), 69 (3), 1053-7
DOI 10.1152/jappl.1990.69.3.1053, PubMed 2246152
Selective positive end-expiratory pressure and cardiac function in dogs
Intensive Care Med, 16 (5), 298-302
DOI 10.1007/BF01706353, PubMed 2212253
Publications 1989
Inosine causing insulin release and increased myocardial uptake of carbohydrates relative to free fatty acids in dogs
Clin Physiol, 9 (1), 27-38
DOI 10.1111/j.1475-097x.1989.tb00953.x, PubMed 2650958
[Treatment of unstable angina pectoris]
Tidsskr Nor Laegeforen, 109 (12), 1268-70
PubMed 2525285
Publications 1988
Plasma concentrations of atrial natriuretic factor in acute left ventricular failure in the dog
Res Exp Med (Berl), 188 (6), 443-50
DOI 10.1007/BF01852002, PubMed 2976974
Unstable angina pectoris. Experience with an acute revascularization program
Acta Med Scand, 224 (1), 19-23
PubMed 2970766
Increased pulmonary vascular capacitance with beta-adrenergic receptor stimulation: an experimental study of the effect of isoproterenol on the pulmonary vascular volume-pressure relationship
Can J Physiol Pharmacol, 66 (2), 85-9
DOI 10.1139/y88-016, PubMed 2897236
Publications 1987
Quantification of effect of pericardium on LV diastolic PV relation in dogs
Am J Physiol, 252 (5 Pt 2), H963-8
DOI 10.1152/ajpheart.1987.252.5.H963, PubMed 2437808
Left ventricular external constraint: relationship between pericardial, pleural and esophageal pressures during positive end-expiratory pressure and volume loading in dogs
Ann Biomed Eng, 15 (3-4), 331-46
DOI 10.1007/BF02584288, PubMed 3310760
Modulation of vascular capacitance by angiotensin and nitroprusside: a mechanism of changes in pericardial pressure
Circulation, 76 (4), 875-83
DOI 10.1161/01.cir.76.4.875, PubMed 3652426
Nonuniformity of pericardial surface pressure in dogs
Circulation, 75 (6), 1229-36
DOI 10.1161/01.cir.75.6.1229, PubMed 3568329
Publications 1986
A mechanism for the nitroglycerin-induced downward shift of the left ventricular diastolic pressure-diameter relation
Am J Cardiol, 57 (8), 673-7
DOI 10.1016/0002-9149(86)90857-x, PubMed 3082176
Reversible and irreversible changes in the dog heart during acute left ventricular failure due to experimental multifocal ischaemia
Acta Pathol Microbiol Immunol Scand A, 94 (3), 177-86
DOI 10.1111/j.1699-0463.1986.tb02983.x, PubMed 3728016
Assessment of pericardial constraint: the relation between right ventricular filling pressure and pericardial pressure measured after pericardiocentesis
J Am Coll Cardiol, 7 (2), 307-14
DOI 10.1016/s0735-1097(86)80496-x, PubMed 3944349
Increased left atrial myocardial blood flow during acute ischemic left ventricular failure
Am Heart J, 111 (4), 798-9
DOI 10.1016/0002-8703(86)90123-7, PubMed 3953407
The relationship between pericardial pressure and right atrial pressure: an intraoperative study
Circulation, 73 (3), 428-32
DOI 10.1161/01.cir.73.3.428, PubMed 3948353
Publications 1985
Effects of secretin infusion on myocardial performance and metabolism in the dog
J Cardiovasc Pharmacol, 7 (6), 1183-7
DOI 10.1097/00005344-198511000-00027, PubMed 2418308
Assessment of pericardial constraint in dogs
Circulation, 71 (1), 158-64
DOI 10.1161/01.cir.71.1.158, PubMed 3964718
The pericardial hypothesis: a mechanism of acute shifts of the left ventricular diastolic pressure-volume relation
Clin Physiol, 5 (5), 403-15
DOI 10.1111/j.1475-097x.1985.tb00771.x, PubMed 3931960
Haemodynamic and metabolic consequences of elevated plasma free fatty acids during acute ischaemic left ventricular failure in dogs
Scand J Clin Lab Invest, 45 (6), 515-20
DOI 10.3109/00365518509155252, PubMed 4070953
Publications 1984
Ventricular diastolic pressure-volume shifts during acute ischemic left ventricular failure in dogs
J Am Coll Cardiol, 3 (4), 966-77
DOI 10.1016/s0735-1097(84)80355-1, PubMed 6707361
Pericardial pressure assessed by right atrial pressure: a basis for calculation of left ventricular transmural pressure
Am Heart J, 108 (3 Pt 1), 603-5
DOI 10.1016/0002-8703(84)90430-7, PubMed 6433685
Mechanism of action of nitrates. Role of changes in venous capacitance and in the left ventricular diastolic pressure-volume relation
Am J Med, 76 (6A), 14-21
DOI 10.1016/0002-9343(84)91038-6, PubMed 6430073
Publications 1983
Apparent depression of right ventricular function after selective reduction of left ventricular inotropy: an interpretation of experimental data utilising a computer-based circulatory model
Med Biol Eng Comput, 21 (5), 548-56
DOI 10.1007/BF02442379, PubMed 6633004
Effects of the beta-adrenergic receptor agonist pirbuterol on cardiac performance during acute ischaemic left ventricular failure in dogs
Eur J Pharmacol, 87 (4), 379-86
DOI 10.1016/0014-2999(83)90076-6, PubMed 6133759
Inosine infusion in dogs with acute ischaemic left ventricular failure: favourable effects on myocardial performance and metabolism
Cardiovasc Res, 17 (4), 192-9
DOI 10.1093/cvr/17.4.192, PubMed 6347379
Acute ischemic left ventricular failure: an experimental study in dogs
Tromsø, 1 b. (flere pag.)
BIBSYS 833064088
Progression of myocardial damage following coronary microembolization in dogs
Acta Pathol Microbiol Immunol Scand A, 91 (2), 115-24
DOI 10.1111/j.1699-0463.1983.tb02735.x, PubMed 6846015
Regional blood flow during acute heart failure in dogs. Role of adipose tissue perfusion in regulating plasma-free fatty acids
Scand J Clin Lab Invest, 43 (4), 285-92
PubMed 6635532
Publications 1982
Vasodilator and inotropic effects of the antiarrhythmic drug melperone
J Cardiovasc Pharmacol, 4 (4), 645-51
DOI 10.1097/00005344-198207000-00017, PubMed 6181340
A reproducible and stable model of acute ischaemic left ventricular failure in dogs
Clin Physiol, 2 (3), 225-39
DOI 10.1111/j.1475-097x.1982.tb00027.x, PubMed 6889941
Effect of hyaluronidase on substrate exchange and blood flow in the ischaemic myocardium of the dog
Clin Physiol, 2 (1), 39-50
DOI 10.1111/j.1475-097x.1982.tb00005.x, PubMed 7201907
Publications 1981
Haemodynamic and metabolic effects of the antiarrhythmic drug melperone during acute left ventricular failure in dogs
Cardiovasc Res, 15 (12), 724-30
DOI 10.1093/cvr/15.12.724, PubMed 7326689
Acute effects of the coronary vasodilator carbocromen on myocardial oxygen consumption, substrate uptake and mechanical performance in intact dogs
Arzneimittelforschung, 31 (7), 1088-91
PubMed 7196756