Ola Gjesdal

  • Consultant Cardiologist, MD, PhD
  • +47 230 73913

Doctor and researcher Ola Gjesdal defended his thesis «Myocardial Infarct of Non-Doppler Echocardiographic Deformation Indices» in December 2009.  He compared new and older methods of ultrasound examination of cardiac function after a heart attack. Today's methods of examining cardiac performance are not sufficiently sensitive to minor changes in cardiac function. Therefore, in case of minor injuries, patients may sometimes notice that cardiac function is reduced before it is possible to detect with today's established ultrasound techniques. There is a strong correlation between the size of the heart attack and morbidity and death after undergoing heart attack. Better detection of injury after a heart attack could thus help improve the follow-up of this patient group.

Ola Gjesdal and colleagues have shown that with new ultrasound technology, we can accurately measure the contraction of the various sections of the heart and that the degree of contraction is closely linked to the spread and extent of the heart attack. The new techniques were compared to already established ones, and showed a better ability to detect impaired cardiac function. Contrast MRI of the heart was used as a standard for the extent of the myocardial infarction. This is the most sensitive method of detecting a heart attack, but it is too expensive and less accessible to be used routinely. The techniques used are accessible on the majority of modern ultrasound devices, and the method can therefore be used immediately by the country's heart specialists.


Publications 2023

Erikssen G, Liestøl K, Aboulhosn J, Wik G, Holmstrøm H, Døhlen G, Gjesdal O, Birkeland S, Hoel TN, Saatvedt KJ, Seem E, Thaulow E, Estensen ME, Lindberg HL (2023)
Preoperative versus postoperative survival in patients with univentricular heart: a nationwide, retrospective study of patients born in 1990-2015
BMJ Open, 13 (7), e069531
DOI 10.1136/bmjopen-2022-069531, PubMed 37491095

Publications 2022

Jensen AS, Jørgensen TH, Christersson C, Nagy E, Sinisalo J, Furenäs E, Gjesdal O, Eriksson P, Vejlstrup N, Johansson B, Hlebowicz J, Greve G, Dellborg M, Skulstad H, Kvidal P, Jokinen E, Sairanen H, Thilén U, Søndergaard L (2022)
Cause-Specific Mortality in Patients During Long-Term Follow-Up After Atrial Switch for Transposition of the Great Arteries
J Am Heart Assoc, 11 (14), e023921
DOI 10.1161/JAHA.121.023921, PubMed 35861834

Publications 2020

Storsten P, Aalen JM, Boe E, Remme EW, Gjesdal O, Larsen CK, Andersen ØS, Eriksen M, Kongsgaard E, Duchenne J, Voigt JU, Smiseth OA, Skulstad H (2020)
Mechanical Effects on Right Ventricular Function From Left Bundle Branch Block and Cardiac Resynchronization Therapy
JACC Cardiovasc Imaging, 13 (7), 1475-1484
DOI 10.1016/j.jcmg.2019.11.016, PubMed 31954643

Publications 2018

Erikssen G, Aboulhosn J, Lin J, Liestøl K, Estensen ME, Gjesdal O, Skulstad H, Døhlen G, Lindberg HL (2018)
Survival in patients with univentricular hearts: the impact of right versus left ventricular morphology
Open Heart, 5 (2), e000902
DOI 10.1136/openhrt-2018-000902, PubMed 30364544

van Mourik MJW, Zaar DVJ, Smulders MW, Heijman J, Lumens J, Dokter JE, Lima Passos V, Schalla S, Knackstedt C, Schummers G, Gjesdal O, Edvardsen T, Bekkers SCAM (2018)
Adding Speckle-Tracking Echocardiography to Visual Assessment of Systolic Wall Motion Abnormalities Improves the Detection of Myocardial Infarction
J Am Soc Echocardiogr, 32 (1), 65-73
DOI 10.1016/j.echo.2018.09.007, PubMed 30340888

Yoneyama K, Venkatesh BA, Wu CO, Mewton N, Gjesdal O, Kishi S, McClelland RL, Bluemke DA, Lima JAC (2018)
Diabetes mellitus and insulin resistance associate with left ventricular shape and torsion by cardiovascular magnetic resonance imaging in asymptomatic individuals from the multi-ethnic study of atherosclerosis
J Cardiovasc Magn Reson, 20 (1), 53
DOI 10.1186/s12968-018-0472-9, PubMed 30064457

Aalen J, Storsten P, Remme EW, Sirnes PA, Gjesdal O, Larsen CK, Kongsgaard E, Boe E, Skulstad H, Hisdal J, Smiseth OA (2018)
Afterload Hypersensitivity in Patients With Left Bundle Branch Block
JACC Cardiovasc Imaging, 12 (6), 967-977
DOI 10.1016/j.jcmg.2017.11.025, PubMed 29361486

Publications 2017

Moreira HT, Nwabuo CC, Armstrong AC, Kishi S, Gjesdal O, Reis JP, Schreiner PJ, Liu K, Lewis CE, Sidney S, Gidding SS, Lima JAC, Ambale-Venkatesh B (2017)
Reference Ranges and Regional Patterns of Left Ventricular Strain and Strain Rate Using Two-Dimensional Speckle-Tracking Echocardiography in a Healthy Middle-Aged Black and White Population: The CARDIA Study
J Am Soc Echocardiogr, 30 (7), 647-658.e2
DOI 10.1016/j.echo.2017.03.010, PubMed 28511859

Nestaas E, Shih JY, Smedsrud MK, Gjesdal O, Hopp E, Haugaa KH, Edvardsen T (2017)
Comparison of Electrocardiography Markers and Speckle Tracking Echocardiography for Assessment of Left Ventricular Myocardial Scar Burden in Patients With Previous Myocardial Infarction
Am J Cardiol, 119 (9), 1307-1312
DOI 10.1016/j.amjcard.2017.01.020, PubMed 28274572

Publications 2016

Gjesdal O, Yoneyama K, Mewton N, Wu C, Gomes AS, Hundley G, Prince M, Shea S, Liu K, Bluemke DA, Lima JA (2016)
Reduced long axis strain is associated with heart failure and cardiovascular events in the multi-ethnic study of Atherosclerosis
J Magn Reson Imaging, 44 (1), 178-85
DOI 10.1002/jmri.25135, PubMed 26731196

Ohyama Y, Ambale-Venkatesh B, Noda C, Chugh AR, Teixido-Tura G, Kim JY, Donekal S, Yoneyama K, Gjesdal O, Redheuil A, Liu CY, Nakamura T, Wu CO, Hundley WG, Bluemke DA, Lima JA (2016)
Association of Aortic Stiffness With Left Ventricular Remodeling and Reduced Left Ventricular Function Measured by Magnetic Resonance Imaging: The Multi-Ethnic Study of Atherosclerosis
Circ Cardiovasc Imaging, 9 (7)
DOI 10.1161/CIRCIMAGING.115.004426, PubMed 27353852

Publications 2015

Kishi S, Teixido-Tura G, Ning H, Venkatesh BA, Wu C, Almeida A, Choi EY, Gjesdal O, Jacobs DR, Schreiner PJ, Gidding SS, Liu K, Lima JA (2015)
Cumulative Blood Pressure in Early Adulthood and Cardiac Dysfunction in Middle Age: The CARDIA Study
J Am Coll Cardiol, 65 (25), 2679-87
DOI 10.1016/j.jacc.2015.04.042, PubMed 26112189

Remme EW, Niederer S, Gjesdal O, Russell K, Hyde ER, Smith N, Smiseth OA (2015)
Factors determining the magnitude of the pre-ejection leftward septal motion in left bundle branch block
Europace, 18 (12), 1905-1913
DOI 10.1093/europace/euv381, PubMed 26612883

Teixido-Tura G, Almeida AL, Choi EY, Gjesdal O, Jacobs DR, Dietz HC, Liu K, Sidney S, Lewis CE, Garcia-Dorado D, Evangelista A, Gidding S, Lima JA (2015)
Determinants of Aortic Root Dilatation and Reference Values Among Young Adults Over a 20-Year Period: Coronary Artery Risk Development in Young Adults Study
Hypertension, 66 (1), 23-9
DOI 10.1161/HYPERTENSIONAHA.115.05156, PubMed 25941347

Publications 2014

Armstrong AC, Jacobs DR, Gidding SS, Colangelo LA, Gjesdal O, Lewis CE, Bibbins-Domingo K, Sidney S, Schreiner PJ, Williams OD, Goff DC, Liu K, Lima JA (2014)
Framingham score and LV mass predict events in young adults: CARDIA study
Int J Cardiol, 172 (2), 350-5
DOI 10.1016/j.ijcard.2014.01.003, PubMed 24507735

Boe E, Russell K, Remme EW, Gjesdal O, Smiseth OA, Skulstad H (2014)
Cardiac responses to left ventricular pacing in hearts with normal electrical conduction: beneficial effect of improved filling is counteracted by dyssynchrony
Am J Physiol Heart Circ Physiol, 307 (3), H370-8
DOI 10.1152/ajpheart.00089.2014, PubMed 24906920

Habibi M, Chahal H, Opdahl A, Gjesdal O, Helle-Valle TM, Heckbert SR, McClelland R, Wu C, Shea S, Hundley G, Bluemke DA, Lima JA (2014)
Association of CMR-measured LA function with heart failure development: results from the MESA study
JACC Cardiovasc Imaging, 7 (6), 570-9
DOI 10.1016/j.jcmg.2014.01.016, PubMed 24813967

Publications 2013

Armstrong AC, Gjesdal O, Almeida A, Nacif M, Wu C, Bluemke DA, Brumback L, Lima JA (2013)
Left ventricular mass and hypertrophy by echocardiography and cardiac magnetic resonance: the multi-ethnic study of atherosclerosis
Echocardiography, 31 (1), 12-20
DOI 10.1111/echo.12303, PubMed 23930739

Gjesdal O, Almeida AL, Hopp E, Beitnes JO, Lunde K, Smith HJ, Lima JA, Edvardsen T (2013)
Long axis strain by MRI and echocardiography in a postmyocardial infarct population
J Magn Reson Imaging, 40 (5), 1247-51
DOI 10.1002/jmri.24485, PubMed 24214923

Hetland A, Haugaa KH, Olseng M, Gjesdal O, Ross S, Saberniak J, Jacobsen MB, Edvardsen T (2013)
Three-month treatment with adaptive servoventilation improves cardiac function and physical activity in patients with chronic heart failure and cheyne-stokes respiration: a prospective randomized controlled trial
Cardiology, 126 (2), 81-90
DOI 10.1159/000350826, PubMed 23941739

Russell K, Eriksen M, Aaberge L, Wilhelmsen N, Skulstad H, Gjesdal O, Edvardsen T, Smiseth OA (2013)
Assessment of wasted myocardial work: a novel method to quantify energy loss due to uncoordinated left ventricular contractions
Am J Physiol Heart Circ Physiol, 305 (7), H996-1003
DOI 10.1152/ajpheart.00191.2013, PubMed 23893165

Schwartz T, Sanner H, Gjesdal O, Flatø B, Sjaastad I (2013)
In juvenile dermatomyositis, cardiac systolic dysfunction is present after long-term follow-up and is predicted by sustained early skin activity
Ann Rheum Dis, 73 (10), 1805-10
DOI 10.1136/annrheumdis-2013-203279, PubMed 23881732

Publications 2012

Armstrong AC, Gidding S, Gjesdal O, Wu C, Bluemke DA, Lima JA (2012)
LV mass assessed by echocardiography and CMR, cardiovascular outcomes, and medical practice
JACC Cardiovasc Imaging, 5 (8), 837-48
DOI 10.1016/j.jcmg.2012.06.003, PubMed 22897998

Russell K, Eriksen M, Aaberge L, Wilhelmsen N, Skulstad H, Remme EW, Haugaa KH, Opdahl A, Fjeld JG, Gjesdal O, Edvardsen T, Smiseth OA (2012)
A novel clinical method for quantification of regional left ventricular pressure-strain loop area: a non-invasive index of myocardial work
Eur Heart J, 33 (6), 724-33
DOI 10.1093/eurheartj/ehs016, PubMed 22315346

Sarvari SI, Gjesdal O, Gude E, Arora S, Andreassen AK, Gullestad L, Geiran O, Edvardsen T (2012)
Early postoperative left ventricular function by echocardiographic strain is a predictor of 1-year mortality in heart transplant recipients
J Am Soc Echocardiogr, 25 (9), 1007-14
DOI 10.1016/j.echo.2012.05.010, PubMed 22727199

Smedsrud MK, Sarvari S, Haugaa KH, Gjesdal O, Ørn S, Aaberge L, Smiseth OA, Edvardsen T (2012)
Duration of myocardial early systolic lengthening predicts the presence of significant coronary artery disease
J Am Coll Cardiol, 60 (12), 1086-93
DOI 10.1016/j.jacc.2012.06.022, PubMed 22939559

Yoneyama K, Gjesdal O, Choi EY, Wu CO, Hundley WG, Gomes AS, Liu CY, McClelland RL, Bluemke DA, Lima JA (2012)
Age, sex, and hypertension-related remodeling influences left ventricular torsion assessed by tagged cardiac magnetic resonance in asymptomatic individuals: the multi-ethnic study of atherosclerosis
Circulation, 126 (21), 2481-90
DOI 10.1161/CIRCULATIONAHA.112.093146, PubMed 23147172

Publications 2011

Gjesdal O, Bluemke DA, Lima JA (2011)
Cardiac remodeling at the population level--risk factors, screening, and outcomes
Nat Rev Cardiol, 8 (12), 673-85
DOI 10.1038/nrcardio.2011.154, PubMed 22027657

Gjesdal O, Remme EW, Opdahl A, Skulstad H, Russell K, Kongsgaard E, Edvardsen T, Smiseth OA (2011)
Mechanisms of abnormal systolic motion of the interventricular septum during left bundle-branch block
Circ Cardiovasc Imaging, 4 (3), 264-73
DOI 10.1161/CIRCIMAGING.110.961417, PubMed 21393502

Goebel B, Gjesdal O, Kottke D, Otto S, Jung C, Lauten A, Figulla HR, Edvardsen T, Poerner TC (2011)
Detection of irregular patterns of myocardial contraction in patients with hypertensive heart disease: a two-dimensional ultrasound speckle tracking study
J Hypertens, 29 (11), 2255-64
DOI 10.1097/HJH.0b013e32834bdd09, PubMed 21946697

Russell K, Smiseth OA, Gjesdal O, Qvigstad E, Norseng PA, Sjaastad I, Opdahl A, Skulstad H, Edvardsen T, Remme EW (2011)
Mechanism of prolonged electromechanical delay in late activated myocardium during left bundle branch block
Am J Physiol Heart Circ Physiol, 301 (6), H2334-43
DOI 10.1152/ajpheart.00644.2011, PubMed 21984549

Smedsrud MK, Pettersen E, Gjesdal O, Svennevig JL, Andersen K, Ihlen H, Edvardsen T (2011)
Detection of left ventricular dysfunction by global longitudinal systolic strain in patients with chronic aortic regurgitation
J Am Soc Echocardiogr, 24 (11), 1253-9
DOI 10.1016/j.echo.2011.08.003, PubMed 21908174

Tsai HR, Gjesdal O, Wethal T, Haugaa KH, Fosså A, Fosså SD, Edvardsen T (2011)
Left ventricular function assessed by two-dimensional speckle tracking echocardiography in long-term survivors of Hodgkin's lymphoma treated by mediastinal radiotherapy with or without anthracycline therapy
Am J Cardiol, 107 (3), 472-7
DOI 10.1016/j.amjcard.2010.09.048, PubMed 21257017

Publications 2010

Beitnes JO, Gjesdal O, Lunde K, Solheim S, Edvardsen T, Arnesen H, Forfang K, Aakhus S (2010)
Left ventricular systolic and diastolic function improve after acute myocardial infarction treated with acute percutaneous coronary intervention, but are not influenced by intracoronary injection of autologous mononuclear bone marrow cells: a 3 year serial echocardiographic sub-study of the randomized-controlled ASTAMI study
Eur J Echocardiogr, 12 (2), 98-106
DOI 10.1093/ejechocard/jeq116, PubMed 20851818

Russell K, Opdahl A, Remme EW, Gjesdal O, Skulstad H, Kongsgaard E, Edvardsen T, Smiseth OA (2010)
Evaluation of left ventricular dyssynchrony by onset of active myocardial force generation: a novel method that differentiates between electrical and mechanical etiologies
Circ Cardiovasc Imaging, 3 (4), 405-14
DOI 10.1161/CIRCIMAGING.109.905539, PubMed 20494943

Publications 2009

Gjesdal O (2009)
Assessment of myocardial infarct by non-doppler echocardiographic deformation indices
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 841, 70, [8] s.
BIBSYS 09405505x, ISBN 978-82-8072-346-8

Gjesdal O (2009)
Assessment of myocardial infarct by non-doppler echocardiographic deformation indices
In Hjerteforum, Supplement, Norsk cardiologisk selskap, Oslo, 22(2009)3, 1 b. (flere pag.)
BIBSYS 10005675x

Gjesdal O, Gude E, Arora S, Leivestad T, Andreassen AK, Gullestad L, Aaberge L, Brunvand H, Edvardsen T, Geiran OR, Simonsen S (2009)
Intra-aortic balloon counterpulsation as a bridge to heart transplantation does not impair long-term survival
Eur J Heart Fail, 11 (7), 709-14
DOI 10.1093/eurjhf/hfp078, PubMed 19515719

Gjesdal O, Vartdal T, Hopp E, Lunde K, Brunvand H, Smith HJ, Edvardsen T (2009)
Left ventricle longitudinal deformation assessment by mitral annulus displacement or global longitudinal strain in chronic ischemic heart disease: are they interchangeable?
J Am Soc Echocardiogr, 22 (7), 823-30
DOI 10.1016/j.echo.2009.04.023, PubMed 19505792

Publications 2008

Gjesdal O, Helle-Valle T, Hopp E, Lunde K, Vartdal T, Aakhus S, Smith HJ, Ihlen H, Edvardsen T (2008)
Noninvasive separation of large, medium, and small myocardial infarcts in survivors of reperfused ST-elevation myocardial infarction: a comprehensive tissue Doppler and speckle-tracking echocardiography study
Circ Cardiovasc Imaging, 1 (3), 189-96, 2 p following 196
DOI 10.1161/CIRCIMAGING.108.784900, PubMed 19808542

Publications 2007

Gjesdal O, Hopp E, Vartdal T, Lunde K, Helle-Valle T, Aakhus S, Smith HJ, Ihlen H, Edvardsen T (2007)
Global longitudinal strain measured by two-dimensional speckle tracking echocardiography is closely related to myocardial infarct size in chronic ischaemic heart disease
Clin Sci (Lond), 113 (6), 287-96
DOI 10.1042/CS20070066, PubMed 17501720

Publications 2003

Gudmundsson A, Gjesdal O, Brenner SL, Fjeldskaar I (2003)
Effects of linking up of discontinuities on fracture growth and groundwater transport
Hydrogeol. J., 11 (1), 84-99
DOI 10.1007/s10040-002-0238-0

Publications 1996

Bjørås M, Gjesdal O, Erickson JD, Torp R, Levy LM, Ottersen OP, Degree M, Storm-Mathisen J, Seeberg E, Danbolt NC (1996)
Cloning and expression of a neuronal rat brain glutamate transporter
Brain Res Mol Brain Res, 36 (1), 163-8
DOI 10.1016/0169-328x(95)00279-2, PubMed 9011753

Trotti D, Rossi D, Gjesdal O, Levy LM, Racagni G, Danbolt NC, Volterra A (1996)
Peroxynitrite inhibits glutamate transporter subtypes
J Biol Chem, 271 (11), 5976-9
DOI 10.1074/jbc.271.11.5976, PubMed 8626378

Publications 1995

Trotti D, Volterra A, Lehre KP, Rossi D, Gjesdal O, Racagni G, Danbolt NC (1995)
Arachidonic acid inhibits a purified and reconstituted glutamate transporter directly from the water phase and not via the phospholipid membrane
J Biol Chem, 270 (17), 9890-5
DOI 10.1074/jbc.270.17.9890, PubMed 7730372

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