John M. Aalen
- PhD fellow, MD
John Aalen graduated as MD from University of Oslo in 2012. Since then he has been working at Vestfold Hospital Trust (Sentralsykehuset i Vestfold), first as a part of his internship and the last year as resident in internal medicine. He joined our research group in April 2014.
His PhD work "Contractile Reserve in Dyssynchrony (CRID): A novel principle to identify candidates for cardiac resynchronization therapy" focuses on identifying candidates for cardiac resynchronization therapy and the effect of increased afterload on the left ventricle during left bundle branch block.
Aalen has presented several abstracts at international and national conferences and has also won several prizes for his work, including the Young Investigator Award for Basic Science at EuroEcho-Imaging Congress in Lisboa in 2017.
Left bundle branch block increases left ventricular diastolic pressure during tachycardia due to incomplete relaxation
J Appl Physiol (1985), 128 (4), 729-738
Acute redistribution of regional left ventricular work by cardiac resynchronization therapy determines long-term remodelling
Eur Heart J Cardiovasc Imaging, 21 (6), 619-628
Regional myocardial work by cardiac magnetic resonance and non-invasive left ventricular pressure: a feasibility study in left bundle branch block
Eur Heart J Cardiovasc Imaging, 21 (2), 143-153
Mechanical Effects on Right Ventricular Function From Left Bundle Branch Block and Cardiac Resynchronization Therapy
JACC Cardiovasc Imaging, 13 (7), 1475-1484
Imaging predictors of response to cardiac resynchronization therapy: left ventricular work asymmetry by echocardiography and septal viability by cardiac magnetic resonance
Eur Heart J (in press)
Left ventricular end-systolic volume is a more sensitive marker of acute response to cardiac resynchronization therapy than contractility indices: insights from an experimental study
Europace, 21 (2), 347-355
Detection of Regional Mechanical Activation of the Left Ventricular Myocardium Using High Frame Rate Ultrasound Imaging
IEEE Trans Med Imaging, 38 (11), 2665-2675
Comparison of two methods for mechanical activation detection using high frame rate ultrasound imaging
IEEE INT ULTRA SYM, 1410-1413
Limitations of hazard ratios in clinical trials
Eur Heart J, 40 (17), 1378-1383
Myocardial Efficiency: A Fundamental Physiological Concept on the Verge of Clinical Impact
JACC Cardiovasc Imaging, 13 (7), 1564-1576
Mechanism of Abnormal Septal Motion in Left Bundle Branch Block: Role of Left Ventricular Wall Interactions and Myocardial Scar
JACC Cardiovasc Imaging, 12 (12), 2402-2413
Editorial commentary: Septal flash - what is behind the flashy name?
Trends Cardiovasc Med, 30 (2), 123-124
Mechanism of harm from left bundle branch block
Trends Cardiovasc Med, 29 (6), 335-342
Afterload Hypersensitivity in Patients With Left Bundle Branch Block
JACC Cardiovasc Imaging, 12 (6), 967-977