❭ Research by medical division ❭ Cancer Medicine ❭ Institute for Cancer Research ❭ Dept. of Cancer Genetics ❭ Translational studies on solid tumours [Helland] ❭ Clinical trials ❭ COM-IT-2

COM-IT-2 Immunotherapy combined with extensive radiotherapy for the treatment of stage IV non-small cell lung cancer

– a phase II randomised clinical and translational trial

  • EudraCT number: 2021-003266
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Home Dept. of Cancer Genetics Translational studies on solid tumours [Helland]

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Recent publications

Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Mark MT, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, King T, Bojmar L, Davies AE, Ararso Y, Zhang T, Zhang H, Hernandez J, Weiss JM, Dumont-Cole VD, Kramer K et al. (2026)
Editorial Expression of Concern: Tumour exosome integrins determine organotropic metastasis
Nature (in press)
DOI 10.1038/s41586-026-10977-8, PubMed 42557336

Horndalsveen H, Haakensen VD, Madebo T, Grønberg BH, Halvorsen TO, Bjaanæs MM, Danielsen BK, Børve M, Kokkvoll S, Boda TSD, Öjlert ÅK, Helland Å (2026)
ctDNA-Based MRD Detection in Stage III NSCLC Treated With Chemoradiotherapy and Durvalumab
J Thorac Oncol, 103992 (in press)
DOI 10.1016/j.jtho.2026.103992, PubMed 42336205

Thunold S, Hernes E, Gyland Mikalsen LT, Farooqi S, Öjlert ÅK, Francis RJ, Nowak AK, Szejniuk WM, Nielsen SS, Cedres S, Perdigo MS, Sørensen JB, Meltzer C, Helland Å, Malinen E, Haakensen VD (2026)
Dual-time-point [18F]FDG-PET/CT as a prognostic biomarker in patients with pleural mesothelioma undergoing immunotherapy
EJNMMI Res (in press)
DOI 10.1186/s13550-026-01469-x, PubMed 42322509

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