Publications 2024

Gregersen I, Kong XY, Kooijman S, Foyn H, Grannes H, Olsen MB, Lone AM, Yang K, Quiles-Jiménez A, Tran M, Øgaard J, Segers FM, Rashidi A, Sagen EL, Lauritzen KH, Pronk ACM, de Boer JF, Holven KB, Melum E, Aukrust P, Taskén K, Holm S, Rensen PCN, Dahl TB, Halvorsen B (2024)
T cells with increased responsiveness cause obesity in mice without diet intervention
iScience, 27 (4), 109471
DOI 10.1016/j.isci.2024.109471, PubMed 38551005

Publications 2023

Myklebust LM, Baumann M, Støve SI, Foyn H, Arnesen T, Haug BE (2023)
Optimized bisubstrate inhibitors for the actin N-terminal acetyltransferase NAA80
Front Chem, 11, 1202501
DOI 10.3389/fchem.2023.1202501, PubMed 37408560

Publications 2019

Ochaya S, Franzén O, Buhwa DA, Foyn H, Butler CE, Stove SI, Tyler KM, Arnesen T, Matovu E, Åslund L, Andersson B (2019)
Characterization of Evolutionarily Conserved Trypanosoma cruzi NatC and NatA-N-Terminal Acetyltransferase Complexes
J Parasitol Res, 2019, 6594212
DOI 10.1155/2019/6594212, PubMed 30956813

Sukonina V, Ma H, Zhang W, Bartesaghi S, Subhash S, Heglind M, Foyn H, Betz MJ, Nilsson D, Lidell ME, Naumann J, Haufs-Brusberg S, Palmgren H, Mondal T, Beg M, Jedrychowski MP, Taskén K, Pfeifer A, Peng XR, Kanduri C, Enerbäck S (2019)
FOXK1 and FOXK2 regulate aerobic glycolysis
Nature, 566 (7743), 279-283
DOI 10.1038/s41586-019-0900-5, PubMed 30700909

Publications 2018

Drazic A, Aksnes H, Marie M, Boczkowska M, Varland S, Timmerman E, Foyn H, Glomnes N, Rebowski G, Impens F, Gevaert K, Dominguez R, Arnesen T (2018)
NAA80 is actin's N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility
Proc Natl Acad Sci U S A, 115 (17), 4399-4404
DOI 10.1073/pnas.1718336115, PubMed 29581253

Goris M, Magin RS, Foyn H, Myklebust LM, Varland S, Ree R, Drazic A, Bhambra P, Støve SI, Baumann M, Haug BE, Marmorstein R, Arnesen T (2018)
Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80
Proc Natl Acad Sci U S A, 115 (17), 4405-4410
DOI 10.1073/pnas.1719251115, PubMed 29581307

Publications 2017

Foyn H, Thompson PR, Arnesen T (2017)
DTNB-Based Quantification of In Vitro Enzymatic N-Terminal Acetyltransferase Activity
Methods Mol Biol, 1574, 9-15
DOI 10.1007/978-1-4939-6850-3_2, PubMed 28315240

Publications 2016

Ribeiro AL, Silva RD, Foyn H, Tiago MN, Rathore OS, Arnesen T, Martinho RG (2016)
Naa50/San-dependent N-terminal acetylation of Scc1 is potentially important for sister chromatid cohesion
Sci Rep, 6, 39118
DOI 10.1038/srep39118, PubMed 27996020

Støve SI, Magin RS, Foyn H, Haug BE, Marmorstein R, Arnesen T (2016)
Crystal Structure of the Golgi-Associated Human Nα-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation
Structure, 24 (7), 1044-56
DOI 10.1016/j.str.2016.04.020, PubMed 27320834

Publications 2015

Ree R, Myklebust LM, Thiel P, Foyn H, Fladmark KE, Arnesen T (2015)
The N-terminal acetyltransferase Naa10 is essential for zebrafish development
Biosci Rep, 35 (5)
DOI 10.1042/BSR20150168, PubMed 26251455

Publications 2013

Foyn H, Jones JE, Lewallen D, Narawane R, Varhaug JE, Thompson PR, Arnesen T (2013)
Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors
ACS Chem Biol, 8 (6), 1121-7
DOI 10.1021/cb400136s, PubMed 23557624

Liszczak G, Goldberg JM, Foyn H, Petersson EJ, Arnesen T, Marmorstein R (2013)
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
Nat Struct Mol Biol, 20 (9), 1098-105
DOI 10.1038/nsmb.2636, PubMed 23912279

Publications 2012

Foyn H, Van Damme P, Støve SI, Glomnes N, Evjenth R, Gevaert K, Arnesen T (2012)
Protein N-terminal acetyltransferases act as N-terminal propionyltransferases in vitro and in vivo
Mol Cell Proteomics, 12 (1), 42-54
DOI 10.1074/mcp.M112.019299, PubMed 23043182

Publications 2011

Van Damme P, Evjenth R, Foyn H, Demeyer K, De Bock PJ, Lillehaug JR, Vandekerckhove J, Arnesen T, Gevaert K (2011)
Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase
Mol Cell Proteomics, 10 (5), M110.004580
DOI 10.1074/mcp.M110.004580, PubMed 21383206