Karolina Ryeng Skagen

  • Senior consultant; MD, PhD
 

Publications 2024

Enriquez BAB, Halling HK, Lund CG, Tennøe B, Brunborg C, Skjelland ME, Aamodt AH, Skagen K (2024)
Exploring the Impact of Age and Pre-Stroke Modified Rankin Scale in Elderly Thrombectomy: A 15-Year Single-Center Experience
Cerebrovasc Dis Extra, 14 (1), 125-133
DOI 10.1159/000540992, PubMed 39191213

Zamani M, Skagen K, Lindberg B, Bjerkeli V, Aukrust P, Halvorsen B, Skjelland M (2024)
Relationship between fibroblast growth factor in plasma and carotid plaque neovascularization: a pilot study
Front Immunol, 15, 1385377
DOI 10.3389/fimmu.2024.1385377, PubMed 38711510

Publications 2023

Stø K, Skagen KR, Valeur J, Yang K, Bjerkeli V, Aukrust P, Skjelland M, Halvorsen B (2023)
Increased plasma levels of non-sugar sweeteners in patients with symptomatic carotid atherosclerosis
Scand Cardiovasc J, 57 (1), 2205068
DOI 10.1080/14017431.2023.2205068, PubMed 37102258

Publications 2022

Enriquez BA, Tennøe B, Nome T, Gjertsen Ø, Nedregaard B, Sletteberg R, Skattør T, Sökjer M, Johansen H, Skagen KR, Skjelland M, Aamodt AH, Lund CG (2022)
[Mechanical thrombectomy in acute ischaemic stroke]
Tidsskr Nor Laegeforen, 142 (7)
DOI 10.4045/tidsskr.21.0577, PubMed 35510464

Schultz NH, Søraas AVL, Sørvoll IH, Akkök ÇA, Vetlesen A, Bhamra JS, Ahlen MT, Holme PA, Aamodt AH, Skagen K, Skattør TH, Skjelland M, Wiedmann MK (2022)
Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: A cohort study
J Stroke Cerebrovasc Dis, 32 (1), 106860
DOI 10.1016/j.jstrokecerebrovasdis.2022.106860, PubMed 36403363

Stø K, Valeur J, Ueland T, Malmstrøm GH, Bjerkeli V, Trøseid M, Hov JR, Holm K, Vestad B, Halvorsen B, Skjelland M, Skagen KR (2022)
Fecal level of butyric acid, a microbiome-derived metabolite, is increased in patients with severe carotid atherosclerosis
Sci Rep, 12 (1), 22378
DOI 10.1038/s41598-022-26759-x, PubMed 36572703

Publications 2021

Holm S, Kared H, Michelsen AE, Kong XY, Dahl TB, Schultz NH, Nyman TA, Fladeby C, Seljeflot I, Ueland T, Stensland M, Mjaaland S, Goll GL, Nissen-Meyer LS, Aukrust P, Skagen K, Gregersen I, Skjelland M, Holme PA, Munthe LA, Halvorsen B (2021)
Immune complexes, innate immunity, and NETosis in ChAdOx1 vaccine-induced thrombocytopenia
Eur Heart J, 42 (39), 4064-4072
DOI 10.1093/eurheartj/ehab506, PubMed 34405870

Niyonzima N, Rahman J, Kunz N, West EE, Freiwald T, Desai JV, Merle NS, Gidon A, Sporsheim B, Lionakis MS, Evensen K, Lindberg B, Skagen K, Skjelland M, Singh P, Haug M, Ruseva MM, Kolev M, Bibby J, Marshall O, O'Brien B, Deeks N, Afzali B, Clark RJ, Woodruff TM et al. (2021)
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation
Sci Immunol, 6 (66), eabf2489
DOI 10.1126/sciimmunol.abf2489, PubMed 34932384

Wiedmann M, Skattør T, Stray-Pedersen A, Romundstad L, Antal EA, Marthinsen PB, Sørvoll IH, Leiknes Ernstsen S, Lund CG, Holme PA, Johansen TO, Brunborg C, Aamodt AH, Schultz NH, Skagen K, Skjelland M (2021)
Vaccine Induced Immune Thrombotic Thrombocytopenia Causing a Severe Form of Cerebral Venous Thrombosis With High Fatality Rate: A Case Series
Front Neurol, 12, 721146
DOI 10.3389/fneur.2021.721146, PubMed 34393988

Aamodt AH, Tauboll E, Eichele T, Romundstad L, Sorteberg A, Wallace S, Fromm A, Raastad MF, Sand T, Skagen K, Eltoft A, Kefaloykos C, Frisvold SK, Nilsen KB, Carlsson M, Brathen G, Bakke I, Horn MA, Wiedmann M, Tennoe B, Totland JA, Ronning OM, Kurz M, Storstein A (2021)
Brain monitoring in hospitals needs to be strengthened
Tidsskr. Nor. Laegeforen., 141 (15), 1431-1433

Aamodt AH, Taubøll E, Eichele T, Romundstad L, Sorteberg A, Wallace S, Fromm A, Raastad MF, Sand T, Skagen K, Eltoft A, Kefaloykos C, Frisvold SK, Nilsen KB, Carlsson M, Bråthen G, Bakke I, Horn MA, Wiedmann M, Tennøe B, Totland JA, Rønning OM, Kurz M, Storstein A (2021)
Brain monitoring in hospitals needs to be strengthened
Tidsskr Nor Laegeforen, 141
DOI 10.4045/tidsskr.21.0412, PubMed 34726044

Publications 2020

Quiles-Jiménez A, Gregersen I, Mittelstedt Leal de Sousa M, Abbas A, Kong XY, Alseth I, Holm S, Dahl TB, Skagen K, Skjelland M, Aukrust P, Bjørås M, Halvorsen B (2020)
N6-methyladenosine in RNA of atherosclerotic plaques: An epitranscriptomic signature of human carotid atherosclerosis
Biochem Biophys Res Commun, 533 (4), 631-637
DOI 10.1016/j.bbrc.2020.09.057, PubMed 33004177

Skagen K, Aamodt AH, Enriquez B, Skjelland M (2020)
[Too little knowledge about blood pressure in cases of ischaemic stroke]
Tidsskr Nor Laegeforen, 140 (9)
DOI 10.4045/tidsskr.20.0323, PubMed 32549003

Skagen K, Aamodt AH, Enriquez B, Skjelland M (2020)
Too little knowledge of blood pressure in ischemic stroke
Tidsskr. Nor. Laegeforen., 140 (9), 870-871

Tancin Lambert A, Kong XY, Ratajczak-Tretel B, Atar D, Russell D, Skjelland M, Bjerkeli V, Skagen K, Coq M, Schordan E, Firat H, Halvorsen B, Aamodt AH (2020)
Biomarkers Associated with Atrial Fibrillation in Patients with Ischemic Stroke: A Pilot Study from the NOR-FIB Study
Cerebrovasc Dis Extra, 10 (1), 11-20
DOI 10.1159/000504529, PubMed 32028277

Publications 2019

Jusufovic M, Skagen K, Krohg-Sørensen K, Skjelland M (2019)
Current Medical and Surgical Stroke Prevention Therapies for Patients with Carotid Artery Stenosis
Curr Neurovasc Res, 16 (1), 96-103
DOI 10.2174/1567202616666190131162811, PubMed 30706783

Lunde NN, Gregersen I, Ueland T, Shetelig C, Holm S, Kong XY, Michelsen AE, Otterdal K, Yndestad A, Broch K, Gullestad L, Nyman TA, Bendz B, Eritsland J, Hoffmann P, Skagen K, Gonçalves I, Nilsson J, Grenegård M, Poreba M, Drag M, Seljeflot I, Sporsheim B, Espevik T, Skjelland M et al. (2019)
Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
Atherosclerosis, 296, 74-82
DOI 10.1016/j.atherosclerosis.2019.12.008, PubMed 31870625

Skagen K, Hetlevik SO, Zamani M, Lilleby V, Skjelland M (2019)
Preclinical Carotid Atherosclerosis in Patients With Juvenile-Onset Mixed Connective Tissue Disease
J Stroke Cerebrovasc Dis, 28 (5), 1295-1301
DOI 10.1016/j.jstrokecerebrovasdis.2019.01.027, PubMed 30772156

Skjelland M, Zamani M, Hetlevik S, Lilleby V, Halvorsen B, Skagen K (2019)
Increased Endothelial Activation in Patients with Mixed Connective Tissue Disease
J Stroke Cerebrovasc Dis, 29 (2), 104563
DOI 10.1016/j.jstrokecerebrovasdis.2019.104563, PubMed 31831329

Zamani M, Skagen K, Russell D, Skjelland M (2019)
Response by Zamani et al to Letter Regarding Article, "Carotid Plaque Neovascularization Detected With Superb Microvascular Imaging Ultrasound Without Using Contrast Media"
Stroke, 51 (1), e12
DOI 10.1161/STROKEAHA.119.027944, PubMed 31813362

Zamani M, Skagen K, Scott H, Lindberg B, Russell D, Skjelland M (2019)
Carotid Plaque Neovascularization Detected With Superb Microvascular Imaging Ultrasound Without Using Contrast Media
Stroke, 50 (11), 3121-3127
DOI 10.1161/STROKEAHA.119.025496, PubMed 31510899

Publications 2018

Skarpengland T, Skjelland M, Kong XY, Skagen K, Holm S, Otterdal K, Dahl CP, Krohg-Sørensen K, Sagen EL, Bjerkeli V, Aamodt AH, Abbas A, Gregersen I, Aukrust P, Halvorsen B, Dahl TB (2018)
Increased Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Ischemic Stroke and Transient Ischemic Attack
J Am Heart Assoc, 7 (2)
DOI 10.1161/JAHA.117.006479, PubMed 29330254

Publications 2017

Johnsrud K, Skagen K, Seierstad T, Skjelland M, Russell D, Revheim ME (2017)
18F-FDG PET/CT for the quantification of inflammation in large carotid artery plaques
J Nucl Cardiol, 26 (3), 883-893
DOI 10.1007/s12350-017-1121-7, PubMed 29209949

Publications 2016

Jusufovic M, Sandset EC, Skagen K, Skjelland M (2016)
Blood Pressure Lowering Treatment in Patients with Carotid Artery Stenosis
Curr Hypertens Rev, 12 (2), 148-55
DOI 10.2174/157340211202160525010133, PubMed 27292176

Skagen K, Evensen K, Scott H, Krohg-Sørensen K, Vatnehol SA, Hol PK, Skjelland M, Russell D (2016)
Semiautomated Magnetic Resonance Imaging Assessment of Carotid Plaque Lipid Content
J Stroke Cerebrovasc Dis, 25 (8), 2004-10
DOI 10.1016/j.jstrokecerebrovasdis.2016.01.043, PubMed 27234919

Skagen K, Skjelland M, Zamani M, Russell D (2016)
Unstable carotid artery plaque: new insights and controversies in diagnostics and treatment
Croat Med J, 57 (4), 311-20
DOI 10.3325/cmj.2016.57.311, PubMed 27586546

Skagen K, Trøseid M, Ueland T, Holm S, Abbas A, Gregersen I, Kummen M, Bjerkeli V, Reier-Nilsen F, Russell D, Svardal A, Karlsen TH, Aukrust P, Berge RK, Hov JE, Halvorsen B, Skjelland M (2016)
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis
Atherosclerosis, 247, 64-9
DOI 10.1016/j.atherosclerosis.2016.01.033, PubMed 26868510

Skarpengland T, Dahl TB, Skjelland M, Scheffler K, de Sousa MML, Gregersen I, Kuśnierczyk A, Sharma A, Slupphaug G, Eide L, Segers FM, Skagen KR, Dahl CP, Russell D, Folkersen L, Krohg-Sørensen K, Holm S, Bjørås M, Aukrust P, Halvorsen B (2016)
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA
Free Radic Biol Med, 97, 386-397
DOI 10.1016/j.freeradbiomed.2016.07.001, PubMed 27381496

Publications 2015

Abbas A, Gregersen I, Holm S, Daissormont I, Bjerkeli V, Krohg-Sørensen K, Skagen KR, Dahl TB, Russell D, Almås T, Bundgaard D, Alteheld LH, Rashidi A, Dahl CP, Michelsen AE, Biessen EA, Aukrust P, Halvorsen B, Skjelland M (2015)
Interleukin 23 levels are increased in carotid atherosclerosis: possible role for the interleukin 23/interleukin 17 axis
Stroke, 46 (3), 793-9
DOI 10.1161/STROKEAHA.114.006516, PubMed 25649806

Halvorsen B, Espeland MZ, Andersen GØ, Yndestad A, Sagen EL, Rashidi A, Knudsen EC, Skjelland M, Skagen KR, Krohg-Sørensen K, Holm S, Ritschel V, Holven KB, Biessen EA, Aukrust P, Dahl TB (2015)
Increased expression of NAMPT in PBMC from patients with acute coronary syndrome and in inflammatory M1 macrophages
Atherosclerosis, 243 (1), 204-10
DOI 10.1016/j.atherosclerosis.2015.09.010, PubMed 26402139

Skagen K, Johnsrud K, Evensen K, Scott H, Krohg-Sørensen K, Reier-Nilsen F, Revheim ME, Fjeld JG, Skjelland M, Russell D (2015)
Carotid plaque inflammation assessed with (18)F-FDG PET/CT is higher in symptomatic compared with asymptomatic patients
Int J Stroke, 10 (5), 730-6
DOI 10.1111/ijs.12430, PubMed 25588553

Skagen K, Marthinsen PB, Skjelland M, Lund CG (2015)
[Fluctuating carotid tumor]
Tidsskr Nor Laegeforen, 135 (4), 337
DOI 10.4045/tidsskr.14.0898, PubMed 25707657

Skagen K, Skjelland M, Russell D, Jacobsen EA (2015)
Large-Vessel Occlusion Stroke: Effect of Recanalization on Outcome Depends on the National Institutes of Health Stroke Scale Score
J Stroke Cerebrovasc Dis, 24 (7), 1532-9
DOI 10.1016/j.jstrokecerebrovasdis.2015.03.020, PubMed 25922156

Publications 2014

Evensen K, Slevolden E, Skagen K, Rønning OM, Brunborg C, Krogstad AL, Russell D (2014)
Increased subclinical atherosclerosis in patients with chronic plaque psoriasis
Atherosclerosis, 237 (2), 499-503
DOI 10.1016/j.atherosclerosis.2014.10.008, PubMed 25463081

Publications 2006

Gill G, Huda B, Boyd A, Skagen K, Wile D, Watson I, van Heyningen C (2006)
Characteristics and mortality of severe hyponatraemia--a hospital-based study
Clin Endocrinol (Oxf), 65 (2), 246-9
DOI 10.1111/j.1365-2265.2006.02583.x, PubMed 16886968

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