Pål Aukrust
- Professor emeritus; MD, PhD
- +47-23 07 19 16
Publications 2024
Toxoplasma gondii infection associated with inflammasome activation and neuronal injury
Sci Rep, 14 (1), 5327
DOI 10.1038/s41598-024-55887-9, PubMed 38438515
Escalated complement activation during hospitalization is associated with higher risk of 60-day mortality in SARS-CoV-2-infected patients
J Intern Med, 296 (1), 80-92
DOI 10.1111/joim.13783, PubMed 38539241
Canonical notch activation in patients with scrub typhus: association with organ dysfunction and poor outcome
Infection, 52 (4), 1357-1365
DOI 10.1007/s15010-024-02192-2, PubMed 38502427
Diagnostics, treatment and outcomes of cardiac sarcoidosis in a Norwegian cohort
Int J Cardiol, 400, 131809
DOI 10.1016/j.ijcard.2024.131809, PubMed 38272129
Clinical profile, microbiology and outcomes in infective endocarditis treated with aortic valve replacement: a multicenter case-control study
BMC Infect Dis, 24 (1), 913
DOI 10.1186/s12879-024-09782-3, PubMed 39227795
Liraglutide and not lifestyle intervention reduces soluble CD163 after comparable weight loss in obese participants with prediabetes or type 2 diabetes mellitus
Cardiovasc Diabetol, 23 (1), 146
DOI 10.1186/s12933-024-02237-8, PubMed 38685051
T cells with increased responsiveness cause obesity in mice without diet intervention
iScience, 27 (4), 109471
DOI 10.1016/j.isci.2024.109471, PubMed 38551005
Plasma legumain in familial hypercholesterolemia: associations with statin use and cardiovascular risk markers
Scand J Clin Lab Invest, 84 (1), 24-29
DOI 10.1080/00365513.2024.2309617, PubMed 38319290
Elevated interleukin 8 and matrix metalloproteinase 9 levels are associated with myocardial pathology in users of anabolic-androgenic steroids
Eur J Prev Cardiol, 31 (12), 1469-1476
DOI 10.1093/eurjpc/zwae126, PubMed 38573232
IL-22 is increased in hospitalized patients with COVID-19 and associates with cardiac involvement
J Infect, 89 (1), 106176
DOI 10.1016/j.jinf.2024.106176, PubMed 38719108
Galectin-3-binding protein and future venous thromboembolism
Res Pract Thromb Haemost, 8 (1), 102311
DOI 10.1016/j.rpth.2023.102311, PubMed 38327613
Chronic HIV Infection Increases Monocyte NLRP3 Inflammasome-Dependent IL-1α and IL-1β Release
Int J Mol Sci, 25 (13)
DOI 10.3390/ijms25137141, PubMed 39000248
Human papilloma virus vaccine induced thrombocytopenia accompanied by a wide spectrum of reversible inflammatory responses - a case report
Scand J Clin Lab Invest, 1-3 (in press)
DOI 10.1080/00365513.2024.2400663, PubMed 39264796
Circular RNA Profile in Atherosclerotic Disease: Regulation during ST-Elevated Myocardial Infarction
Int J Mol Sci, 25 (16)
DOI 10.3390/ijms25169014, PubMed 39201700
Retraction Note: Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 14 (1), 3704
DOI 10.1038/s41598-024-54117-6, PubMed 38355714
Neutrophil Extracellular Traps in ST-Segment Elevation Myocardial Infarction: Reduced by Tocilizumab and Associated With Infarct Size
JACC Adv, 3 (9), 101193
DOI 10.1016/j.jacadv.2024.101193, PubMed 39247678
CD38 deficient mice are not protected from atherosclerosis
Biochem Biophys Res Commun, 705, 149734
DOI 10.1016/j.bbrc.2024.149734, PubMed 38430607
Gene expression profiling in elderly patients with familial hypercholesterolemia with and without coronary heart disease
Atherosclerosis, 392, 117507
DOI 10.1016/j.atherosclerosis.2024.117507, PubMed 38663317
Extracellular matrix remodelling pathway in peripheral blood mononuclear cells from severe COVID-19 patients: an explorative study
Front Immunol, 15, 1379570
DOI 10.3389/fimmu.2024.1379570, PubMed 38957465
α1-Antichymotrypsin Complex (SERPINA3) Is an Independent Predictor of All-Cause but Not Cardiovascular Mortality in Patients Hospitalized for Chest Pain of Suspected Coronary Origin
Cardiology, 149 (4), 338-346
DOI 10.1159/000537919, PubMed 38402860
Chemokine ligand 18 predicts all-cause mortality in patients hospitalized with chest pain of suspected coronary origin
Int J Cardiol Cardiovasc Risk Prev, 21, 200264
DOI 10.1016/j.ijcrp.2024.200264, PubMed 38596196
SLAMF1-derived peptide exhibits cardio protection after permanent left anterior descending artery ligation in mice
Front Immunol, 15, 1383505
DOI 10.3389/fimmu.2024.1383505, PubMed 38686379
Continuous infusion of resolvin D2 in combination with Angiotensin-II show contrary effects on blood pressure and intracardiac artery remodeling
Biochem Biophys Res Commun, 733, 150706
DOI 10.1016/j.bbrc.2024.150706, PubMed 39305571
Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity
Genome Med, 16 (1), 27
DOI 10.1186/s13073-024-01296-6, PubMed 38331891
Cognitive and inflammatory heterogeneity in severe mental illness: Translating findings from blood to brain
Brain Behav Immun, 118, 287-299
DOI 10.1016/j.bbi.2024.03.014, PubMed 38461955
Longitudinal course of inflammatory-cognitive subgroups across first treatment severe mental illness and healthy controls
Psychol Med, 1-11 (in press)
DOI 10.1017/S003329172400206X, PubMed 39354711
C-C Motif Ligand 7 (CCL7) and C-C Motif Chemokine Receptor 3 (CCR3) dysregulation in patients with scrub typhus and association with mortality
J Infect Dis (in press)
DOI 10.1093/infdis/jiae401, PubMed 39190223
High dose statin treatment reduces circulating Dickkopf-1 following acute myocardial infarction
Int J Cardiol, 406, 132035
DOI 10.1016/j.ijcard.2024.132035, PubMed 38604450
Markers of extracellular matrix degradation and inflammasome activation are associated with carotid plaques in virally suppressed people with HIV in Botswana
AIDS (in press)
DOI 10.1097/QAD.0000000000004014, PubMed 39283741
High viral loads combined with inflammatory markers predict disease severity in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 296 (3), 249-259
DOI 10.1111/joim.13820, PubMed 39011800
Effect of tocilizumab on endothelial and platelet-derived CXC-chemokines and their association with inflammation and myocardial injury in STEMI patients undergoing primary PCI
Int J Cardiol, 418, 132613 (in press)
DOI 10.1016/j.ijcard.2024.132613, PubMed 39374793
Altered Genome-Wide DNA Methylation in the Duodenum of Common Variable Immunodeficiency Patients
J Clin Immunol, 44 (6), 133
DOI 10.1007/s10875-024-01726-5, PubMed 38780872
Relationship between fibroblast growth factor in plasma and carotid plaque neovascularization: a pilot study
Front Immunol, 15, 1385377
DOI 10.3389/fimmu.2024.1385377, PubMed 38711510
Publications 2023
Cardiac Involvement in Systemic and Local Vasculitides: The Value of Noninvasive Multimodality Imaging
Curr Probl Cardiol, 48 (8), 101718
DOI 10.1016/j.cpcardiol.2023.101718, PubMed 37003450
Recurrent pericarditis
Tidsskr Nor Laegeforen, 143 (8)
DOI 10.4045/tidsskr.22.0580, PubMed 37254974
Long-term survival after liver transplantation in patients with common variable immunodeficiency
Liver Transpl, 29 (8), 894-899
DOI 10.1097/LVT.0000000000000130, PubMed 36932715
Procollagen type 1 N-terminal propeptide is associated with adverse outcome in acute chest pain of suspected coronary origin
Front Cardiovasc Med, 10, 1191055
DOI 10.3389/fcvm.2023.1191055, PubMed 37731526
Impact of the von Willebrand factor-ADAMTS-13 axis on the risk of future venous thromboembolism
J Thromb Haemost, 21 (5), 1227-1237
DOI 10.1016/j.jtha.2023.01.024, PubMed 36736832
Increased cardiovascular mortality during the COVID-19 pandemic: do not neglect causality
Eur Heart J Open, 3 (6), oead119
DOI 10.1093/ehjopen/oead119, PubMed 38089856
Combined effect of high factor VIII levels and high mean platelet volume on the risk of future incident venous thromboembolism
J Thromb Haemost, 21 (10), 2844-2853
DOI 10.1016/j.jtha.2023.06.022, PubMed 37393000
Systemic inflammation early after kidney transplantation is associated with long-term graft loss: a cohort study
Front Immunol, 14, 1253991
DOI 10.3389/fimmu.2023.1253991, PubMed 37849758
Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness
Schizophr Bull, 49 (3), 635-645
DOI 10.1093/schbul/sbac191, PubMed 36462169
Disturbed lipid profile in common variable immunodeficiency - a pathogenic loop of inflammation and metabolic disturbances
Front Immunol, 14, 1199727
DOI 10.3389/fimmu.2023.1199727, PubMed 37545531
Increased ferroptosis in leukocytes from preeclamptic women involving the long non-coding taurine upregulated gene 1 (TUG1)
J Intern Med, 295 (2), 181-195
DOI 10.1111/joim.13732, PubMed 37870937
Platelet and mitochondrial RNA is decreased in plasma-derived extracellular vesicles in women with preeclampsia-an exploratory study
BMC Med, 21 (1), 458
DOI 10.1186/s12916-023-03178-x, PubMed 37996819
Increased Plasma Levels of Triglyceride-Enriched Lipoproteins Associate with Systemic Inflammation, Lipopolysaccharides, and Gut Dysbiosis in Common Variable Immunodeficiency
J Clin Immunol, 43 (6), 1229-1240
DOI 10.1007/s10875-023-01475-x, PubMed 36995502
Circulating markers of extracellular matrix remodelling in severe COVID-19 patients
J Intern Med, 294 (6), 784-797
DOI 10.1111/joim.13725, PubMed 37718572
Genetic Overlap Between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts
Biol Psychiatry, 95 (1), 62-71
DOI 10.1016/j.biopsych.2023.06.008, PubMed 37348803
Proteogenomic integration reveals CXCL10 as a potentially downstream causal mediator for IL-6 signaling on atherosclerosis
medRxiv
DOI 10.1101/2023.03.24.23287543, PubMed 37034659
Proteogenomic Data Integration Reveals CXCL10 as a Potentially Downstream Causal Mediator for IL-6 Signaling on Atherosclerosis
Circulation, 149 (9), 669-683
DOI 10.1161/CIRCULATIONAHA.123.064974, PubMed 38152968
Severely ill COVID-19 patients have altered circulating levels of proteins controlling the epitranscriptome
J Infect, 86 (6), 593-595
DOI 10.1016/j.jinf.2023.03.002, PubMed 36889510
Increased levels of NT-proBNP and troponin T 2 years after coronary artery bypass grafting complicated by mediastinitis
Front Cardiovasc Med, 10, 1008825
DOI 10.3389/fcvm.2023.1008825, PubMed 36824453
Troponin T and N-Terminal Pro-Brain Natriuretic Peptide Are Associated with Long-Term All-Cause Mortality in Patients with Post-Sternotomy Mediastinitis following Coronary Artery Bypass Grafting: A 15-Year Follow-Up Study
Cardiology, 148 (6), 599-603
DOI 10.1159/000533631, PubMed 37586344
Microvascular function and inflammatory activation in Takotsubo cardiomyopathy
ESC Heart Fail, 10 (5), 3216-3222
DOI 10.1002/ehf2.14461, PubMed 37537779
Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities
Schizophr Bull, 49 (5), 1345-1354
DOI 10.1093/schbul/sbad082, PubMed 37319439
Increased plasma levels of non-sugar sweeteners in patients with symptomatic carotid atherosclerosis
Scand Cardiovasc J, 57 (1), 2205068
DOI 10.1080/14017431.2023.2205068, PubMed 37102258
Author Correction: Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
NPJ Vaccines, 8 (1), 4
DOI 10.1038/s41541-023-00600-6, PubMed 36697432
Coagulopathy and adverse outcomes in hospitalized patients with COVID-19: results from the NOR-Solidarity trial
Res Pract Thromb Haemost, 8 (1), 102289
DOI 10.1016/j.rpth.2023.102289, PubMed 38292350
Fatty Acids Composition and HIV Infection: Altered Levels of n-6 Polyunsaturated Fatty Acids Are Associated with Disease Progression
Viruses, 15 (7)
DOI 10.3390/v15071613, PubMed 37515299
Low-density lipoprotein particles carrying proinflammatory proteins with altered aggregation pattern detected in COVID-19 patients 3 months after hospitalization
J Infect, 86 (5), 489-492
DOI 10.1016/j.jinf.2023.02.024, PubMed 36822413
Cytokine pattern in patients with ST-elevation myocardial infarction treated with the interleukin-6 receptor antagonist tocilizumab
Open Heart, 10 (2)
DOI 10.1136/openhrt-2023-002301, PubMed 37591633
Publications 2022
Podocan and Adverse Clinical Outcome in Patients Admitted With Suspected Acute Coronary Syndromes
Front Cardiovasc Med, 9, 867944
DOI 10.3389/fcvm.2022.867944, PubMed 35669474
Circulating T Cell Activation and Exhaustion Markers Are Associated With Radiation Pneumonitis and Poor Survival in Non-Small-Cell Lung Cancer
Front Immunol, 13, 875152
DOI 10.3389/fimmu.2022.875152, PubMed 35911763
Corrigendum: Circulating T cell activation and exhaustion markers are associated with radiation pneumonitis and poor survival in non-small-cell lung cancer
Front Immunol, 13, 1051156
DOI 10.3389/fimmu.2022.1051156, PubMed 36263024
Iron homeostasis in heart transplant recipients randomized to ferric derisomaltose or placebo
Clin Transplant, 36 (7), e14695
DOI 10.1111/ctr.14695, PubMed 35532871
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
Schizophr Bull, 48 (1), 37-46
DOI 10.1093/schbul/sbab106, PubMed 34499169
Blood Milieu in Acute Myocardial Infarction Reprograms Human Macrophages for Trauma Repair
Adv Sci (Weinh), 10 (5), e2203053
DOI 10.1002/advs.202203053, PubMed 36526599
Raised Serum Markers of T Cell Activation and Exhaustion in Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency
J Clin Immunol, 42 (7), 1553-1563
DOI 10.1007/s10875-022-01318-1, PubMed 35789314
Elevated plasma levels of plasminogen activator inhibitor-1 are associated with risk of future incident venous thromboembolism
J Thromb Haemost, 20 (7), 1618-1626
DOI 10.1111/jth.15701, PubMed 35289062
Omicron Variant Generates a Higher and More Sustained Viral Load in Nasopharynx and Saliva Than the Delta Variant of SARS-CoV-2
Viruses, 14 (11)
DOI 10.3390/v14112420, PubMed 36366518
CXCL16 associates with adverse outcome and cardiac involvement in hospitalized patients with Covid-19
J Infect, 85 (6), 702-769
DOI 10.1016/j.jinf.2022.09.029, PubMed 36216188
Inflammation in the early phase after kidney transplantation is associated with increased long-term all-cause mortality
Am J Transplant, 22 (8), 2016-2027
DOI 10.1111/ajt.17047, PubMed 35352462
Interleukin-6 inhibition in ST-elevation myocardial infarction: Immune cell profile in the randomised ASSAIL-MI trial
EBioMedicine, 80, 104013
DOI 10.1016/j.ebiom.2022.104013, PubMed 35504178
NEIL3-deficient bone marrow displays decreased hematopoietic capacity and reduced telomere length
Biochem Biophys Rep, 29, 101211
DOI 10.1016/j.bbrep.2022.101211, PubMed 35079641
Duodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses
J Allergy Clin Immunol, 151 (3), 767-777
DOI 10.1016/j.jaci.2022.09.029, PubMed 36220400
Fetuin-A mediates the difference in adipose tissue insulin resistance between young adult pakistani and norwegian patients with type 2 diabetes
BMC Endocr Disord, 22 (1), 208
DOI 10.1186/s12902-022-01127-y, PubMed 35978354
Markers of cellular senescence is associated with persistent pulmonary pathology after COVID-19 infection
Infect Dis (Lond), 54 (12), 918-923
DOI 10.1080/23744235.2022.2113135, PubMed 35984738
Remdesivir modifies interferon response in hospitalized COVID-19 patients
J Infect, 85 (5), 573-607
DOI 10.1016/j.jinf.2022.07.021, PubMed 35914611
The Effect of Protease-Activated Receptor-1 (PAR-1) Inhibition on Endothelial-Related Biomarkers in Patients with Coronary Artery Disease
Thromb Haemost, 123 (5), 510-521
DOI 10.1055/s-0042-1760256, PubMed 36588289
DNA Repair Mechanisms are Activated in Circulating Lymphocytes of Hospitalized Covid-19 Patients
J Inflamm Res, 15, 6629-6644
DOI 10.2147/JIR.S379331, PubMed 36514358
Hepcidin predicts 5-year mortality after community-acquired pneumonia
Infect Dis (Lond), 54 (6), 403-409
DOI 10.1080/23744235.2021.2022194, PubMed 35057702
Markers of extracellular matrix remodeling and systemic inflammation in patients with heritable thoracic aortic diseases
Front Cardiovasc Med, 9, 1073069
DOI 10.3389/fcvm.2022.1073069, PubMed 36606286
Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
Biol Psychiatry, 93 (2), 187-196
DOI 10.1016/j.biopsych.2022.06.029, PubMed 36182530
Effects of liraglutide vs. lifestyle changes on soluble suppression of tumorigenesis-2 (sST2) and galectin-3 in obese subjects with prediabetes or type 2 diabetes after comparable weight loss
Cardiovasc Diabetol, 21 (1), 36
DOI 10.1186/s12933-022-01469-w, PubMed 35277168
A man in his fifties with recurrent urticaria, fever and joint pain
Tidsskr Nor Laegeforen, 142 (4)
DOI 10.4045/tidsskr.21.0028, PubMed 35239264
Inflammation and cognition in severe mental illness: patterns of covariation and subgroups
Mol Psychiatry, 28 (3), 1284-1292
DOI 10.1038/s41380-022-01924-w, PubMed 36577840
Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity
Front Immunol, 13, 964525
DOI 10.3389/fimmu.2022.964525, PubMed 36159859
Corticosteroids and superinfections in COVID-19 patients on invasive mechanical ventilation
J Infect, 85 (1), 57-63
DOI 10.1016/j.jinf.2022.05.015, PubMed 35605805
Serum markers of cardiac complications in a systemic sclerosis cohort
Sci Rep, 12 (1), 4661
DOI 10.1038/s41598-022-08815-8, PubMed 35304587
Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
NPJ Vaccines, 7 (1), 174
DOI 10.1038/s41541-022-00586-7, PubMed 36585405
Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies
J Intern Med, 292 (5), 816-828
DOI 10.1111/joim.13549, PubMed 35982589
High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19
J Infect Dis, 226 (12), 2150-2160
DOI 10.1093/infdis/jiac313, PubMed 35876699
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology
Platelets, 33 (4), 640-644
DOI 10.1080/09537104.2022.2042238, PubMed 35225150
Circulating levels and prognostic cut-offs of sST2, hs-cTnT, and NT-proBNP in women vs. men with chronic heart failure
ESC Heart Fail, 9 (4), 2084-2095
DOI 10.1002/ehf2.13883, PubMed 35510529
Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
J Intern Med, 291 (6), 801-812
DOI 10.1111/joim.13458, PubMed 35212063
Immune marker levels in severe mental disorders: associations with polygenic risk scores of related mental phenotypes and psoriasis
Transl Psychiatry, 12 (1), 38
DOI 10.1038/s41398-022-01811-6, PubMed 35082268
Limited association between infections, autoimmune disease and genetic risk and immune activation in severe mental disorders
Prog Neuropsychopharmacol Biol Psychiatry, 116, 110511
DOI 10.1016/j.pnpbp.2022.110511, PubMed 35063598
Publications 2021
Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
Psychol Med, 53 (4), 1479-1488
DOI 10.1017/S0033291721003056, PubMed 35387700
Targeting IL-6 Trans-Signaling: Amplifying the Benefits of IL-6 Inhibition in Myocardial Infarction
JACC Basic Transl Sci, 6 (5), 444-446
DOI 10.1016/j.jacbts.2021.01.007, PubMed 34102669
Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial
EBioMedicine, 70, 103511
DOI 10.1016/j.ebiom.2021.103511, PubMed 34329947
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
Ann Intern Med, 174 (9), 1261-1269
DOI 10.7326/M21-0653, PubMed 34251903
The use of eculizumab in Capnocytophaga canimorsus associated thrombotic microangiopathy: a case report
BMC Infect Dis, 21 (1), 137
DOI 10.1186/s12879-021-05789-2, PubMed 33526010
Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction
J Am Coll Cardiol, 77 (15), 1845-1855
DOI 10.1016/j.jacc.2021.02.049, PubMed 33858620
Combined effects of plasma von Willebrand factor and platelet measures on the risk of incident venous thromboembolism
Blood, 138 (22), 2269-2277
DOI 10.1182/blood.2021011494, PubMed 34161566
Plasma levels of von Willebrand factor and future risk of incident venous thromboembolism
Blood Adv, 5 (1), 224-232
DOI 10.1182/bloodadvances.2020003135, PubMed 33570640
Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency-Features of CT and 18F-FDG Positron Emission Tomography/CT in Clinically Progressive Disease
Front Immunol, 11, 617985
DOI 10.3389/fimmu.2020.617985, PubMed 33584710
Plasma Levels of Leptin and Risk of Future Incident Venous Thromboembolism
Thromb Haemost, 122 (4), 560-569
DOI 10.1055/s-0041-1732295, PubMed 34264516
Elevated plasma D-dimer levels are associated with risk of future incident venous thromboembolism
Thromb Res, 208, 121-126
DOI 10.1016/j.thromres.2021.10.020, PubMed 34763296
Tocilizumab increases citrullinated histone 3 in non-ST segment elevation myocardial infarction
Open Heart, 8 (1)
DOI 10.1136/openhrt-2020-001492, PubMed 33972404
Immune complexes, innate immunity, and NETosis in ChAdOx1 vaccine-induced thrombocytopenia
Eur Heart J, 42 (39), 4064-4072
DOI 10.1093/eurheartj/ehab506, PubMed 34405870
The Alternative Complement Pathway Is Activated Without a Corresponding Terminal Pathway Activation in Patients With Heart Failure
Front Immunol, 12, 800978
DOI 10.3389/fimmu.2021.800978, PubMed 35003128
Real-World Experiences With Facilitated Subcutaneous Immunoglobulin Substitution in Patients With Hypogammaglobulinemia, Using a Three-Step Ramp-Up Schedule
Front Immunol, 12, 670547
DOI 10.3389/fimmu.2021.670547, PubMed 34012453
Synergistic Interferon-Alpha-Based Combinations for Treatment of SARS-CoV-2 and Other Viral Infections
Viruses, 13 (12)
DOI 10.3390/v13122489, PubMed 34960758
A Nationwide Study of GATA2 Deficiency in Norway-the Majority of Patients Have Undergone Allo-HSCT
J Clin Immunol, 42 (2), 404-420
DOI 10.1007/s10875-021-01189-y, PubMed 34893945
NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype
Sci Rep, 11 (1), 19749
DOI 10.1038/s41598-021-98820-0, PubMed 34611194
Endonuclease V Regulates Atherosclerosis Through C-C Motif Chemokine Ligand 2-Mediated Monocyte Infiltration
J Am Heart Assoc, 10 (14), e020656
DOI 10.1161/JAHA.120.020656, PubMed 34259011
Neutrophil count predicts clinical outcome in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 291 (2), 241-243
DOI 10.1111/joim.13377, PubMed 34411368
Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication
Elife, 10
DOI 10.7554/eLife.59828, PubMed 34343089
Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence
Sci Rep, 11 (1), 19735
DOI 10.1038/s41598-021-99140-z, PubMed 34611223
Author Correction: Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence
Sci Rep, 11 (1), 22572
DOI 10.1038/s41598-021-00917-z, PubMed 34782619
Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9
Sci Rep, 11 (1), 23205
DOI 10.1038/s41598-021-02547-x, PubMed 34853380
Targeting the Inflammasome in Cardiovascular Disease
JACC Basic Transl Sci, 7 (1), 84-98
DOI 10.1016/j.jacbts.2021.08.006, PubMed 35128212
Hepcidin and Ferritin Predict Microbial Etiology in Community-Acquired Pneumonia
Open Forum Infect Dis, 8 (4), ofab082
DOI 10.1093/ofid/ofab082, PubMed 33880390
IL-18 and IL-18 binding protein are related to disease severity and parasitemia during falciparum malaria
BMC Infect Dis, 21 (1), 1073
DOI 10.1186/s12879-021-06751-y, PubMed 34663245
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
Atherosclerosis, 324, 123-132
DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552
Low CETP activity and unique composition of large VLDL and small HDL in women giving birth to small-for-gestational age infants
Sci Rep, 11 (1), 6213
DOI 10.1038/s41598-021-85777-3, PubMed 33737686
Lung CD4+ T-cells in patients with lung fibrosis produce pro-fibrotic interleukin-13 together with interferon-γ
Eur Respir J, 57 (3)
DOI 10.1183/13993003.00983-2020, PubMed 33154027
Altered Plasma Fatty Acids Associate with Gut Microbial Composition in Common Variable Immunodeficiency
J Clin Immunol, 42 (1), 146-157
DOI 10.1007/s10875-021-01146-9, PubMed 34669143
Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation
Brain Behav Immun, 99, 299-306
DOI 10.1016/j.bbi.2021.10.017, PubMed 34758379
Reduced Cardiac Function by Echocardiography in a Minority of COVID-19 Patients 3 Months after Hospitalization
J Am Soc Echocardiogr, 35 (2), 243-244
DOI 10.1016/j.echo.2021.10.014, PubMed 34758386
The relationship between Fibroblast Growth Factor 23 (FGF23) and cardiac MRI findings following primary PCI in patients with acute first time STEMI
Int J Cardiol Heart Vasc, 33, 100727
DOI 10.1016/j.ijcha.2021.100727, PubMed 33665349
Circulating regulators of the wingless pathway in precapillary pulmonary hypertension
Respirology, 26 (6), 574-581
DOI 10.1111/resp.14048, PubMed 33830565
Secreted Wnt antagonists in scrub typhus
PLoS Negl Trop Dis, 15 (4), e0009185
DOI 10.1371/journal.pntd.0009185, PubMed 33914733
Increased inflammatory markers reflecting fibrogenesis are independently associated with cardiac involvement in hospitalized COVID-19 patients
J Infect, 82 (5), 186-230
DOI 10.1016/j.jinf.2021.01.017, PubMed 33516748
Growth differentiation factor 15 predicts poor prognosis in patients with heart failure and reduced ejection fraction and anemia: results from RED-HF
Clin Res Cardiol, 111 (4), 440-450
DOI 10.1007/s00392-021-01944-6, PubMed 34611778
NT-proBNP for Risk Prediction in Heart Failure: Identification of Optimal Cutoffs Across Body Mass Index Categories
JACC Heart Fail, 9 (9), 653-663
DOI 10.1016/j.jchf.2021.05.014, PubMed 34246607
Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID-19
J Neurol, 268 (10), 3574-3583
DOI 10.1007/s00415-021-10517-6, PubMed 33743046
Angiopoietin-2 and angiopoietin-like 4 protein provide prognostic information in patients with suspected acute coronary syndrome
J Intern Med, 290 (4), 894-909
DOI 10.1111/joim.13339, PubMed 34237166
Complement component 7 is associated with total- and cardiac death in chest-pain patients with suspected acute coronary syndrome
BMC Cardiovasc Disord, 21 (1), 496
DOI 10.1186/s12872-021-02306-w, PubMed 34649504
Publications 2020
Circulating levels and prognostic value of soluble ST2 in heart failure are less influenced by age than N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin T
Eur J Heart Fail, 22 (11), 2078-2088
DOI 10.1002/ejhf.1701, PubMed 31919929
Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells
Brain Behav Immun, 87, 634-644
DOI 10.1016/j.bbi.2020.02.008, PubMed 32109548
YKL-40 (Chitinase-3-Like Protein 1) Serum Levels in Aortic Stenosis
Circ Heart Fail, 13 (10), e006643
DOI 10.1161/CIRCHEARTFAILURE.119.006643, PubMed 32962417
Plasma parasitemia as assessed by quantitative PCR in relation to clinical disease severity in African adults with falciparum malaria with and without HIV co-infection
Infection, 48 (3), 367-373
DOI 10.1007/s15010-020-01399-3, PubMed 32077073
Novel Insights Into the Effects of Interleukin 6 Antagonism in Non-ST-Segment-Elevation Myocardial Infarction Employing the SOMAscan Proteomics Platform
J Am Heart Assoc, 9 (12), e015628
DOI 10.1161/JAHA.119.015628, PubMed 32515246
Legumain in Acute Coronary Syndromes: A Substudy of the PLATO (Platelet Inhibition and Patient Outcomes) Trial
J Am Heart Assoc, 9 (17), e016360
DOI 10.1161/JAHA.120.016360, PubMed 32809893
Plasma levels of growth differentiation factor 15 are associated with future risk of venous thromboembolism
Blood, 136 (16), 1863-1870
DOI 10.1182/blood.2019004572, PubMed 32645137
Elevated markers of gut leakage and inflammasome activation in COVID-19 patients with cardiac involvement
J Intern Med, 289 (4), 523-531
DOI 10.1111/joim.13178, PubMed 32976665
Soluble T-Cell Immunoglobulin Mucin Domain-3 Is Associated With Hepatitis C Virus Coinfection and Low-Grade Inflammation During Chronic Human Immunodeficiency Virus Infection
Open Forum Infect Dis, 7 (2), ofaa033
DOI 10.1093/ofid/ofaa033, PubMed 32055642
Soluble Markers of Interleukin 1 Activation as Predictors of First-Time Myocardial Infarction in HIV-Infected Individuals
J Infect Dis, 221 (4), 506-509
DOI 10.1093/infdis/jiz253, PubMed 31077280
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538
Subjects with familial hypercholesterolemia have lower aortic valve area and higher levels of inflammatory biomarkers
J Clin Lipidol, 15 (1), 134-141
DOI 10.1016/j.jacl.2020.12.006, PubMed 33358307
Anti-inflammatory effects of non-statin low-density lipoprotein cholesterol-lowering drugs: an unused potential?
Scand Cardiovasc J, 54 (5), 274-279
DOI 10.1080/14017431.2020.1775878, PubMed 32500743
Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19
Sci Rep, 10 (1), 21697
DOI 10.1038/s41598-020-78710-7, PubMed 33303843
Commentary: Gut Antibody Deficiency in a Mouse Model of CVID Results in Spontaneous Development of a Gluten-Sensitive Enteropathy
Front Immunol, 11, 1921
DOI 10.3389/fimmu.2020.01921, PubMed 32983117
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma
Nucleic Acids Res, 48 (8), 4463-4479
DOI 10.1093/nar/gkaa115, PubMed 32083667
Rosuvastatin alters the genetic composition of the human gut microbiome
Sci Rep, 10 (1), 5397
DOI 10.1038/s41598-020-62261-y, PubMed 32214138
Distinct patterns of soluble leukocyte activation markers are associated with etiology and outcomes in precapillary pulmonary hypertension
Sci Rep, 10 (1), 18540
DOI 10.1038/s41598-020-75654-w, PubMed 33122779
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction
JACC Basic Transl Sci, 5 (12), 1210-1224
DOI 10.1016/j.jacbts.2020.09.013, PubMed 33426377
Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency
Front Immunol, 11, 574500
DOI 10.3389/fimmu.2020.574500, PubMed 33042155
Low fibre intake is associated with gut microbiota alterations in chronic heart failure
ESC Heart Fail, 7 (2), 456-466
DOI 10.1002/ehf2.12596, PubMed 31978943
Interleukin 18 (IL-18) and its binding protein (IL-18BP) are increased in patients with epilepsy suggesting low-grade systemic inflammation
Seizure, 80, 221-225
DOI 10.1016/j.seizure.2020.05.018, PubMed 32659652
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis
EBioMedicine, 60, 102985
DOI 10.1016/j.ebiom.2020.102985, PubMed 32927275
[Elevated serum ferritin is not only a sign of liver failure]
Tidsskr Nor Laegeforen, 140 (8)
DOI 10.4045/tidsskr.20.0376, PubMed 32463199
Plasma levels of interleukin 27 in falciparum malaria is increased independently of co-infection with HIV: potential immune-regulatory role during malaria
BMC Infect Dis, 20 (1), 65
DOI 10.1186/s12879-020-4783-8, PubMed 31964363
Exploring the potential effect of paricalcitol on markers of inflammation in de novo renal transplant recipients
PLoS One, 15 (12), e0243759
DOI 10.1371/journal.pone.0243759, PubMed 33326471
N6-methyladenosine in RNA of atherosclerotic plaques: An epitranscriptomic signature of human carotid atherosclerosis
Biochem Biophys Res Commun, 533 (4), 631-637
DOI 10.1016/j.bbrc.2020.09.057, PubMed 33004177
Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders
Front Psychiatry, 11, 672
DOI 10.3389/fpsyt.2020.00672, PubMed 32754070
Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling
Biochem Biophys Res Commun, 523 (4), 867-873
DOI 10.1016/j.bbrc.2020.01.018, PubMed 31955888
NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet
Sci Rep, 10 (1), 21006
DOI 10.1038/s41598-020-76497-1, PubMed 33273482
Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder
Front Psychiatry, 11, 642
DOI 10.3389/fpsyt.2020.00642, PubMed 32714224
Hemophagocytic lymphohistiocytosis in a patient with COVID-19 treated with tocilizumab: a case report
J Med Case Rep, 14 (1), 187
DOI 10.1186/s13256-020-02503-9, PubMed 33054818
Haemophagocytic lymphohistiocytosis in COVID-19 cases?
Tidsskr Nor Laegeforen, 140 (6)
DOI 10.4045/tidsskr.20.0240, PubMed 32321221
A man in his forties with increasing shortness of breath
Tidsskr Nor Laegeforen, 140 (6)
DOI 10.4045/tidsskr.19.0692, PubMed 32321231
Elevated levels of the secreted wingless agonist R-spondin 3 in preeclamptic pregnancies
J Hypertens, 38 (7), 1347-1354
DOI 10.1097/HJH.0000000000002362, PubMed 31990902
Elevated plasma sTIM-3 levels in patients with severe COVID-19
J Allergy Clin Immunol, 147 (1), 92-98
DOI 10.1016/j.jaci.2020.09.007, PubMed 32971109
Distinct and early increase in circulating MMP-9 in COVID-19 patients with respiratory failure
J Infect, 81 (3), e41-e43
DOI 10.1016/j.jinf.2020.06.061, PubMed 32603675
Elevated Cholesteryl Ester Transfer Protein Activity Early in Pregnancy Predicts Prediabetes 5 Years Later
J Clin Endocrinol Metab, 105 (3)
DOI 10.1210/clinem/dgz119, PubMed 31665383
Reduced levels of circulating adhesion molecules in adolescents with early-onset psychosis
NPJ Schizophr, 6 (1), 20
DOI 10.1038/s41537-020-00112-5, PubMed 32811840
Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results
N Engl J Med, 384 (6), 497-511
DOI 10.1056/NEJMoa2023184, PubMed 33264556
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
Cell Rep, 30 (12), 4165-4178.e7
DOI 10.1016/j.celrep.2020.02.063, PubMed 32209476
[Not Available]
Tidsskr Nor Laegeforen, 140
DOI 10.4045/tidsskr.20.0390, PubMed 32378869
How does COVID-19 affect the brain?
Tidsskr Nor Laegeforen, 140 (10)
DOI 10.4045/tidsskr.20.0444, PubMed 32602331
Publications 2019
C-X-C Ligand 16 Is an Independent Predictor of Cardiovascular Death and Morbidity in Acute Coronary Syndromes
Arterioscler Thromb Vasc Biol, 39 (11), 2402-2410
DOI 10.1161/ATVBAHA.119.312633, PubMed 31554419
Rationale for the ASSAIL-MI-trial: a randomised controlled trial designed to assess the effect of tocilizumab on myocardial salvage in patients with acute ST-elevation myocardial infarction (STEMI)
Open Heart, 6 (2), e001108
DOI 10.1136/openhrt-2019-001108, PubMed 31673391
Variation in Serum PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9), Cardiovascular Disease Risk, and an Investigation of Potential Unanticipated Effects of PCSK9 Inhibition
Circ Genom Precis Med, 12 (1), e002335
DOI 10.1161/CIRCGEN.118.002335, PubMed 30645169
Homeostatic Chemokines and Prognosis in Patients With Acute Coronary Syndromes
J Am Coll Cardiol, 74 (6), 774-782
DOI 10.1016/j.jacc.2019.06.030, PubMed 31395128
Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children
Mol Nutr Food Res, 63 (7), e1800990
DOI 10.1002/mnfr.201800990, PubMed 30702198
Variant in ERAP1 promoter region is associated with low expression in a patient with a Behçet-like MHC-I-opathy
J Hum Genet, 65 (3), 325-335
DOI 10.1038/s10038-019-0709-y, PubMed 31873220
Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction
EBioMedicine, 46, 264-273
DOI 10.1016/j.ebiom.2019.07.024, PubMed 31345784
Effect of hormone replacement therapy on atherogenic lipid profile in postmenopausal women
Thromb Res, 184, 1-7
DOI 10.1016/j.thromres.2019.10.005, PubMed 31677448
Levels of Lipoprotein (a) in patients with coronary artery disease with and without inflammatory rheumatic disease: a cross-sectional study
BMJ Open, 9 (5), e030651
DOI 10.1136/bmjopen-2019-030651, PubMed 31079089
Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: a dysregulation with potential inflammatory effects
Open Heart, 6 (2), e001098
DOI 10.1136/openhrt-2019-001098, PubMed 31798913
Risk factors for lung cancer in COPD - results from the Bergen COPD cohort study
Respir Med, 152, 81-88
DOI 10.1016/j.rmed.2019.04.019, PubMed 31128615
Effects of interval training on inflammatory biomarkers in patients with ischemic heart failure
Scand Cardiovasc J, 53 (4), 213-219
DOI 10.1080/14017431.2019.1629004, PubMed 31169417
Selective IgA deficiency in humans is associated with reduced gut microbial diversity
J Allergy Clin Immunol, 143 (5), 1969-1971.e11
DOI 10.1016/j.jaci.2019.01.019, PubMed 30707969
Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 9 (1), 167 (Retracted)
DOI 10.1038/s41598-018-35367-7, PubMed 30655568
Pentraxin-3 vs C-reactive protein and other prognostic biomarkers in acute coronary syndrome: A substudy of the Platelet Inhibition and Patients Outcomes (PLATO) trial
Eur Heart J Acute Cardiovasc Care, 9 (4), 313-322
DOI 10.1177/2048872619846334, PubMed 31017470
Plasma tumour necrosis factor correlates with mRNA expression of tumour necrosis factor and mitochondrial transcription factors in skeletal muscle in patients with chronic heart failure treated with cardiac resynchronization therapy: potential role in myopathy
Eur J Prev Cardiol, 27 (19), 2362-2366
DOI 10.1177/2047487319855796, PubMed 31389718
Plasma levels of mannose-binding lectin and future risk of venous thromboembolism
J Thromb Haemost, 17 (10), 1661-1669
DOI 10.1111/jth.14539, PubMed 31220397
Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
Atherosclerosis, 296, 74-82
DOI 10.1016/j.atherosclerosis.2019.12.008, PubMed 31870625
Impaired HDL Function Amplifies Systemic Inflammation in Common Variable Immunodeficiency
Sci Rep, 9 (1), 9427
DOI 10.1038/s41598-019-45861-1, PubMed 31263122
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors
Psychol Med, 49 (10), 1749-1757
DOI 10.1017/S0033291718004142, PubMed 30688187
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors - ERRATUM
Psychol Med, 49 (10), 1758
DOI 10.1017/S0033291719000291, PubMed 30803457
Lipoprotein(a) concentration is associated with plasma arachidonic acid in subjects with familial hypercholesterolaemia
Br J Nutr, 122 (7), 790-799
DOI 10.1017/S0007114519001600, PubMed 31262370
Profiling of immune-related gene expression in children with familial hypercholesterolaemia
J Intern Med, 287 (3), 310-321
DOI 10.1111/joim.13001, PubMed 31631426
Serum levels of inflammation-related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers
Int J Cancer, 146 (1), 223-235
DOI 10.1002/ijc.32638, PubMed 31444972
Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma
Clin Exp Immunol, 197 (1), 74-82
DOI 10.1111/cei.13283, PubMed 30821848
Encephalitis and aseptic meningitis: short-term and long-term outcome, quality of life and neuropsychological functioning
Sci Rep, 9 (1), 16158
DOI 10.1038/s41598-019-52570-2, PubMed 31695095
Increased Complement Factor B and Bb Levels Are Associated with Mortality in Patients with Severe Aortic Stenosis
J Immunol, 203 (7), 1973-1980
DOI 10.4049/jimmunol.1801244, PubMed 31492744
Inflammatory biomarkers are associated with aetiology and predict outcomes in community-acquired pneumonia: results of a 5-year follow-up cohort study
ERJ Open Res, 5 (1)
DOI 10.1183/23120541.00014-2019, PubMed 30863773
NLRP3 Inflammasome: A Novel Player in Metabolically Induced Inflammation-Potential Influence on the Myocardium
J Cardiovasc Pharmacol, 74 (4), 276-284
DOI 10.1097/FJC.0000000000000704, PubMed 31584530
NLRP3 Inflammasome Promotes Myocardial Remodeling During Diet-Induced Obesity
Front Immunol, 10, 1621
DOI 10.3389/fimmu.2019.01621, PubMed 31379826
Index of microvascular resistance to assess the effect of rosuvastatin on microvascular function in women with chest pain and no obstructive coronary artery disease: A double-blind randomized study
Catheter Cardiovasc Interv, 94 (5), 660-668
DOI 10.1002/ccd.28157, PubMed 30790446
Mammalian Target of Rapamycin (mTOR) and the Proteasome Attenuates IL-1β Expression in Primary Mouse Cardiac Fibroblasts
Front Immunol, 10, 1285
DOI 10.3389/fimmu.2019.01285, PubMed 31244838
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection
J Heart Lung Transplant, 38 (10), 1097-1103
DOI 10.1016/j.healun.2019.06.003, PubMed 31301965
Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol, 316 (6), L999-L1012
DOI 10.1152/ajplung.00322.2018, PubMed 30908936
CCL21 and prognosis in acute coronary syndrome
Aging (Albany NY), 11 (21), 9225-9226
DOI 10.18632/aging.102443, PubMed 31694981
Adipokines and macrophage markers during pregnancy-Possible role for sCD163 in prediction and progression of gestational diabetes mellitus
Diabetes Metab Res Rev, 35 (3), e3114
DOI 10.1002/dmrr.3114, PubMed 30548982
ALCAM predicts future cardiovascular death in acute coronary syndromes: Insights from the PLATO trial
Atherosclerosis, 293, 35-41
DOI 10.1016/j.atherosclerosis.2019.11.031, PubMed 31835039
Admission Levels of DKK1 (Dickkopf-1) Are Associated With Future Cardiovascular Death in Patients With Acute Coronary Syndromes
Arterioscler Thromb Vasc Biol, 39 (2), 294-302
DOI 10.1161/ATVBAHA.118.311042, PubMed 30580572
Interruption of the CXCL13/CXCR5 Chemokine Axis Enhances Plasma IgM Levels and Attenuates Atherosclerosis Development
Thromb Haemost, 120 (2), 344-347
DOI 10.1055/s-0039-3400746, PubMed 31837653
Increased interleukin 18 activity in adolescents with early-onset psychosis is associated with cortisol and depressive symptoms
Psychoneuroendocrinology, 112, 104513
DOI 10.1016/j.psyneuen.2019.104513, PubMed 31761332
Low Cellular NAD+ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
J Immunol, 203 (6), 1598-1608
DOI 10.4049/jimmunol.1801382, PubMed 31427442
Publications 2018
Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT
J Mol Endocrinol, 60 (3), 171-183
DOI 10.1530/JME-17-0182, PubMed 29330151
T cell and monocyte/macrophage activation markers associate with adverse outcome, but give limited prognostic value in anemic patients with heart failure: results from RED-HF
Clin Res Cardiol, 108 (2), 133-141
DOI 10.1007/s00392-018-1331-2, PubMed 30051179
Effect of Everolimus Initiation and Calcineurin Inhibitor Elimination on Cardiac Allograft Vasculopathy in De Novo Heart Transplant Recipients
Circ Heart Fail, 11 (9), e004050
DOI 10.1161/CIRCHEARTFAILURE.117.004050, PubMed 30354362
Levels and prognostic impact of circulating markers of inflammation, endothelial activation and extracellular matrix remodelling in patients with lung cancer and chronic obstructive pulmonary disease
BMC Cancer, 18 (1), 739
DOI 10.1186/s12885-018-4659-0, PubMed 30005623
An association between YKL-40 and type 2 diabetes in psychotic disorders
Acta Psychiatr Scand, 139 (1), 37-45
DOI 10.1111/acps.12971, PubMed 30328100
Plasma hepcidin is associated with future risk of venous thromboembolism
Blood Adv, 2 (11), 1191-1197
DOI 10.1182/bloodadvances.2018018465, PubMed 29844204
Runaway Train: A Leaky Radiosensitive SCID with Skin Lesions and Multiple Lymphomas
Case Reports Immunol, 2018, 2053716
DOI 10.1155/2018/2053716, PubMed 29888014
Inflammatory and related biomarkers are associated with post-transplant diabetes mellitus in kidney recipients: a retrospective study
Transpl Int, 31 (5), 510-519
DOI 10.1111/tri.13116, PubMed 29341300
Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction
Sci Rep, 8 (1), 6725
DOI 10.1038/s41598-018-25168-3, PubMed 29712976
CCL21 as a Potential Serum Biomarker for Pulmonary Arterial Hypertension in Systemic Sclerosis
Arthritis Rheumatol, 70 (10), 1644-1653
DOI 10.1002/art.40534, PubMed 29687634
Augmented concentrations of CX3CL1 are associated with interstitial lung disease in systemic sclerosis
PLoS One, 13 (11), e0206545
DOI 10.1371/journal.pone.0206545, PubMed 30457999
Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder
Transl Psychiatry, 8 (1), 55
DOI 10.1038/s41398-018-0102-1, PubMed 29507296
Attenuated Notch signaling in schizophrenia and bipolar disorder
Sci Rep, 8 (1), 5349
DOI 10.1038/s41598-018-23703-w, PubMed 29593239
Autoimmunity and Inflammation in CVID: a Possible Crosstalk between Immune Activation, Gut Microbiota, and Epigenetic Modifications
J Clin Immunol, 39 (1), 30-36
DOI 10.1007/s10875-018-0574-z, PubMed 30465180
Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction
Int J Cardiol, 271, 1-7
DOI 10.1016/j.ijcard.2018.04.136, PubMed 29961572
Prevalence and prognostic implication of iron deficiency and anaemia in patients with severe aortic stenosis
Open Heart, 5 (2), e000901
DOI 10.1136/openhrt-2018-000901, PubMed 30613413
Prediction of Gestational Diabetes Mellitus and Pre-diabetes 5 Years Postpartum using 75 g Oral Glucose Tolerance Test at 14-16 Weeks' Gestation
Sci Rep, 8 (1), 13392
DOI 10.1038/s41598-018-31614-z, PubMed 30190548
Design of the GutHeart-targeting gut microbiota to treat heart failure-trial: a Phase II, randomized clinical trial
ESC Heart Fail, 5 (5), 977-984
DOI 10.1002/ehf2.12332, PubMed 30088346
Circulating delta-like Notch ligand 1 is correlated with cardiac allograft vasculopathy and suppressed in heart transplant recipients on everolimus-based immunosuppression
Am J Transplant, 19 (4), 1050-1060
DOI 10.1111/ajt.15141, PubMed 30312541
Serum neutrophil gelatinase-associated lipocalin (NGAL) concentration is independently associated with mortality in patients with acute coronary syndrome
Int J Cardiol, 262, 79-84
DOI 10.1016/j.ijcard.2018.03.028, PubMed 29622507
Differential expression of vitamin D associated genes in the aorta of coronary artery disease patients with and without rheumatoid arthritis
PLoS One, 13 (8), e0202346
DOI 10.1371/journal.pone.0202346, PubMed 30138371
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock
ESC Heart Fail, 5 (3), 292-301
DOI 10.1002/ehf2.12266, PubMed 29424484
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
Front Immunol, 9, 2035
DOI 10.3389/fimmu.2018.02035, PubMed 30258440
Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction
Int J Cardiol, 268, 187-192
DOI 10.1016/j.ijcard.2018.05.032, PubMed 29853279
Soluble markers of neutrophil, T-cell and monocyte activation are associated with disease severity and parasitemia in falciparum malaria
BMC Infect Dis, 18 (1), 670
DOI 10.1186/s12879-018-3593-8, PubMed 30563486
High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections
J Neuroinflammation, 15 (1), 327
DOI 10.1186/s12974-018-1366-3, PubMed 30470234
Systemic and Airway Inflammation after Exposure to Fumes from Military Small Arms
Am J Respir Crit Care Med, 197 (10), 1349-1353
DOI 10.1164/rccm.201709-1857LE, PubMed 29144885
Low Levels of Immunoglobulins and Mannose-Binding Lectin Are Not Associated With Etiology, Severity, or Outcome in Community-Acquired Pneumonia
Open Forum Infect Dis, 5 (2), ofy002
DOI 10.1093/ofid/ofy002, PubMed 29410975
Increased Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Ischemic Stroke and Transient Ischemic Attack
J Am Heart Assoc, 7 (2)
DOI 10.1161/JAHA.117.006479, PubMed 29330254
NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction
Am J Physiol Endocrinol Metab, 315 (5), E912-E923
DOI 10.1152/ajpendo.00461.2017, PubMed 30016155
Pentraxin 3 level is elevated in hereditary hemorrhagic telangiectasia and reflects the severity of disease-associated epistaxis
Laryngoscope, 129 (1), E44-E49
DOI 10.1002/lary.27548, PubMed 30329172
Tenders for HIV medicines are not academically justified
Tidsskr. Nor. Laegeforen., 138 (20), 1912-1913
[Tendering for HIV drugs is not clinically justified]
Tidsskr Nor Laegeforen, 138 (20)
DOI 10.4045/tidsskr.18.0808, PubMed 30539614
Treatment of sleep apnea in patients with paroxysmal atrial fibrillation: design and rationale of a randomized controlled trial
Scand Cardiovasc J, 52 (6), 372-377
DOI 10.1080/14017431.2019.1567933, PubMed 30638392
Pro-gastrin-releasing peptide and outcome in patients with heart failure and anaemia: results from the RED-HF study
ESC Heart Fail, 5 (6), 1052-1059
DOI 10.1002/ehf2.12312, PubMed 30145817
Serum PCSK9 is modified by interleukin-6 receptor antagonism in patients with hypercholesterolaemia following non-ST-elevation myocardial infarction
Open Heart, 5 (2), e000765
DOI 10.1136/openhrt-2017-000765, PubMed 30258647
Serum lipoprotein(a) is not modified by interleukin-6 receptor antagonism or associated with inflammation in non-ST-elevation myocardial infarction
Int J Cardiol, 274, 348-350
DOI 10.1016/j.ijcard.2018.06.093, PubMed 29961573
Osteoprotegerin Is Associated With Major Bleeding But Not With Cardiovascular Outcomes in Patients With Acute Coronary Syndromes: Insights From the PLATO (Platelet Inhibition and Patient Outcomes) Trial
J Am Heart Assoc, 7 (2)
DOI 10.1161/JAHA.117.007009, PubMed 29330256
Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders
Schizophr Res, 205, 45-50
DOI 10.1016/j.schres.2018.08.007, PubMed 30126813
Publications 2017
Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy
Sci Rep, 7 (1), 3490
DOI 10.1038/s41598-017-03625-9, PubMed 28615692
Wnt5a is elevated in heart failure and affects cardiac fibroblast function
J Mol Med (Berl), 95 (7), 767-777
DOI 10.1007/s00109-017-1529-1, PubMed 28357477
Associations of brain-natriuretic peptide, high-sensitive troponin T, and high-sensitive C-reactive protein with outcomes in severe aortic stenosis
PLoS One, 12 (6), e0179304
DOI 10.1371/journal.pone.0179304, PubMed 28604834
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation
J Immunol, 199 (8), 2910-2920
DOI 10.4049/jimmunol.1700302, PubMed 28855312
Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function
Arterioscler Thromb Vasc Biol, 37 (6), 1157-1167
DOI 10.1161/ATVBAHA.116.308187, PubMed 28408371
Comprehensive lipid and metabolite profiling of children with and without familial hypercholesterolemia: A cross-sectional study
Atherosclerosis, 266, 48-57
DOI 10.1016/j.atherosclerosis.2017.09.021, PubMed 28963918
Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice
Mediators Inflamm, 2017, 9450439
DOI 10.1155/2017/9450439, PubMed 28490840
Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation
PLoS One, 12 (11), e0188387
DOI 10.1371/journal.pone.0188387, PubMed 29176764
TLR9 stimulation of B-cells induces transcription of p53 and prevents spontaneous and irradiation-induced cell death independent of DNA damage responses. Implications for Common variable immunodeficiency
PLoS One, 12 (10), e0185708
DOI 10.1371/journal.pone.0185708, PubMed 28973009
Effect of interleukin-6 inhibition on coronary microvascular and endothelial function in myocardial infarction
Heart, 103 (19), 1521-1527
DOI 10.1136/heartjnl-2016-310875, PubMed 28432157
A Study of TNF Pathway Activation in Schizophrenia and Bipolar Disorder in Plasma and Brain Tissue
Schizophr Bull, 43 (4), 881-890
DOI 10.1093/schbul/sbw183, PubMed 28049760
Bariatric surgery reduces fasting total fatty acids and increases n-3 polyunsaturated fatty acids in morbidly obese individuals
Scand J Clin Lab Invest, 77 (8), 628-633
DOI 10.1080/00365513.2017.1393691, PubMed 29069988
CVID and Celiac Disease
Am J Gastroenterol, 112 (2), 393
DOI 10.1038/ajg.2016.551, PubMed 28154406
High physical fitness is associated with reduction in basal- and exercise-induced inflammation
Scand J Med Sci Sports, 28 (1), 172-179
DOI 10.1111/sms.12878, PubMed 28314078
Leptin and adiponectin as predictors of cardiovascular risk after gestational diabetes mellitus
Cardiovasc Diabetol, 16 (1), 5
DOI 10.1186/s12933-016-0492-4, PubMed 28068986
CXC chemokine ligand 16 is increased in gestational diabetes mellitus and preeclampsia and associated with lipoproteins in gestational diabetes mellitus at 5 years follow-up
Diab Vasc Dis Res, 14 (6), 525-533
DOI 10.1177/1479164117728011, PubMed 28856928
Large Reduction in Adiponectin During Pregnancy Is Associated With Large-for-Gestational-Age Newborns
J Clin Endocrinol Metab, 102 (7), 2552-2559
DOI 10.1210/jc.2017-00289, PubMed 28460045
Increased Secondary/Primary Bile Acid Ratio in Chronic Heart Failure
J Card Fail, 23 (9), 666-671
DOI 10.1016/j.cardfail.2017.06.007, PubMed 28688889
Persistent increase in TNF and IL-1 markers in severe mental disorders suggests trait-related inflammation: a one year follow-up study
Acta Psychiatr Scand, 136 (4), 400-408
DOI 10.1111/acps.12783, PubMed 28815548
The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy
J Cardiovasc Transl Res, 10 (4), 401-410
DOI 10.1007/s12265-017-9748-y, PubMed 28474304
Limited Added Value of Circulating Inflammatory Biomarkers in Chronic Heart Failure
JACC Heart Fail, 5 (4), 256-264
DOI 10.1016/j.jchf.2017.01.008, PubMed 28359413
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262
Severe hypertriglyceridemia in Norway: prevalence, clinical and genetic characteristics
Lipids Health Dis, 16 (1), 115
DOI 10.1186/s12944-017-0511-9, PubMed 28606150
Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells
Blood, 129 (14), 1927-1939
DOI 10.1182/blood-2016-08-734236, PubMed 28209719
The alternative complement pathway is dysregulated in patients with chronic heart failure
Sci Rep, 7, 42532
DOI 10.1038/srep42532, PubMed 28195242
Osteoprotegerin levels in ST-elevation myocardial infarction: Temporal profile and association with myocardial injury and left ventricular function
PLoS One, 12 (3), e0173034
DOI 10.1371/journal.pone.0173034, PubMed 28253327
Cytokine responses, microbial aetiology and short-term outcome in community-acquired pneumonia
Eur J Clin Invest, 48 (1)
DOI 10.1111/eci.12865, PubMed 29171871
Defective IL-4 signaling in T cells defines severe common variable immunodeficiency
J Autoimmun, 81, 110-119
DOI 10.1016/j.jaut.2017.04.004, PubMed 28476239
Extracellular matrix markers and risk of myocardial infarction: The HUNT Study in Norway
Eur J Prev Cardiol, 24 (11), 1161-1167
DOI 10.1177/2047487317703826, PubMed 28429960
Monocyte/macrophage and T cell activation markers are not independently associated with MI risk in healthy individuals - results from the HUNT Study
Int J Cardiol, 243, 502-504
DOI 10.1016/j.ijcard.2017.05.106, PubMed 28615143
A Young, Immunocompetent Woman with Small Bowel and Hepatic Mucormycosis Successfully Treated with Aggressive Surgical Debridements and Antifungal Therapy
Case Rep Infect Dis, 2017, 4173246
DOI 10.1155/2017/4173246, PubMed 29435377
Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study
Eur J Heart Fail, 20 (2), 268-277
DOI 10.1002/ejhf.988, PubMed 28960777
Immediate response in markers of inflammation and angiogenesis during exercise: a randomised cross-over study in heart transplant recipients
Open Heart, 4 (2), e000635
DOI 10.1136/openhrt-2017-000635, PubMed 29225901
Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses
Brain Behav Immun, 65, 342-349
DOI 10.1016/j.bbi.2017.06.005, PubMed 28619247
Publications 2016
Brief Report: Proatherogenic Cytokine Microenvironment in the Aortic Adventitia of Patients With Rheumatoid Arthritis
Arthritis Rheumatol, 68 (6), 1361-6
DOI 10.1002/art.39574, PubMed 26749303
Low YKL-40 in chronic heart failure may predict beneficial effects of statins: analysis from the controlled rosuvastatin multinational trial in heart failure (CORONA)
Biomarkers, 22 (3-4), 261-267
DOI 10.1080/1354750X.2016.1204003, PubMed 27325138
Data on circulating leukocyte subpopulations and inflammatory proteins in children with familial hypercholesterolemia and healthy children
Data Brief, 10, 587-592
DOI 10.1016/j.dib.2016.12.042, PubMed 28070551
Altered leukocyte distribution under hypercholesterolemia: A cross-sectional study in children with familial hypercholesterolemia
Atherosclerosis, 256, 67-74
DOI 10.1016/j.atherosclerosis.2016.11.031, PubMed 28024183
Low Circulating Levels of Mitochondrial and High Levels of Nuclear DNA Predict Mortality in Chronic Heart Failure
J Card Fail, 22 (10), 823-8
DOI 10.1016/j.cardfail.2016.06.013, PubMed 27349571
Plasma Levels of Marine n-3 Fatty Acids Are Inversely Correlated With Proinflammatory Markers sTNFR1 and IL-6 in Renal Transplant Recipients
J Ren Nutr, 27 (3), 161-168
DOI 10.1053/j.jrn.2016.09.008, PubMed 27838193
Microbiota-Dependent Marker TMAO Is Elevated in Silent Ischemia but Is Not Associated With First-Time Myocardial Infarction in HIV Infection
J Acquir Immune Defic Syndr, 71 (2), 130-6
DOI 10.1097/QAI.0000000000000843, PubMed 26413854
LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro
Diabetologia, 59 (10), 2134-44
DOI 10.1007/s00125-016-4036-y, PubMed 27421726
Patients with depression display cytokine levels in serum and cerebrospinal fluid similar to patients with diffuse neurological symptoms without a defined diagnosis
Neuropsychiatr Dis Treat, 12, 817-22
DOI 10.2147/NDT.S101925, PubMed 27110115
High Level of Chemokine CCL18 Is Associated With Pulmonary Function Deterioration, Lung Fibrosis Progression, and Reduced Survival in Systemic Sclerosis
Chest, 150 (2), 299-306
DOI 10.1016/j.chest.2016.03.004, PubMed 26997242
Risk Factors for Long-Term Mortality after Hospitalization for Community-Acquired Pneumonia: A 5-Year Prospective Follow-Up Study
PLoS One, 11 (2), e0148741
DOI 10.1371/journal.pone.0148741, PubMed 26849359
Vitamin D Status and Long-Term Mortality in Community-Acquired Pneumonia: Secondary Data Analysis from a Prospective Cohort
PLoS One, 11 (7), e0158536
DOI 10.1371/journal.pone.0158536, PubMed 27367810
Macrophage migration inhibitory factor, a role in COPD
Am J Physiol Lung Cell Mol Physiol, 311 (1), L1-7
DOI 10.1152/ajplung.00461.2015, PubMed 27190066
Liver transplantation in patients with primary antibody deficiency
J Allergy Clin Immunol, 139 (5), 1708-1710.e2
DOI 10.1016/j.jaci.2016.10.025, PubMed 27931972
A Cross-Sectional Study of the Prevalence of Gastrointestinal Symptoms and Pathology in Patients With Common Variable Immunodeficiency
Am J Gastroenterol, 111 (10), 1467-1475
DOI 10.1038/ajg.2016.329, PubMed 27527747
Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation
Mucosal Immunol, 9 (6), 1455-1465
DOI 10.1038/mi.2016.18, PubMed 26982597
Serum osteoprotegrin (OPG) in subclinical atherosclerosis in systemic lupus erythematosus
Lupus, 26 (8), 865-870
DOI 10.1177/0961203316682101, PubMed 27927880
Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial
Eur Heart J, 37 (30), 2406-13
DOI 10.1093/eurheartj/ehw171, PubMed 27161611
The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls
Gut, 66 (4), 611-619
DOI 10.1136/gutjnl-2015-310500, PubMed 26887816
Elevated trimethylamine-N-oxide (TMAO) is associated with poor prognosis in primary sclerosing cholangitis patients with normal liver function
United European Gastroenterol J, 5 (4), 532-541
DOI 10.1177/2050640616663453, PubMed 28588885
Circulating PCSK9 and Risk of Myocardial Infarction: The HUNT Study in Norway
JACC Basic Transl Sci, 1 (7), 568-575
DOI 10.1016/j.jacbts.2016.06.007, PubMed 30167541
Low circulating pentraxin 3 levels in pregnancy is associated with gestational diabetes and increased apoB/apoA ratio: a 5-year follow-up study
Cardiovasc Diabetol, 15, 23
DOI 10.1186/s12933-016-0345-1, PubMed 26842615
Impact of Systemic Inflammation on the Progression of Gestational Diabetes Mellitus
Curr Diab Rep, 16 (4), 26
DOI 10.1007/s11892-016-0715-9, PubMed 26879309
Inflammatory evidence for the psychosis continuum model
Psychoneuroendocrinology, 67, 189-97
DOI 10.1016/j.psyneuen.2016.02.011, PubMed 26923849
Complement activation by cholesterol crystals triggers a subsequent cytokine response
Mol Immunol, 84, 43-50
DOI 10.1016/j.molimm.2016.09.019, PubMed 27692470
Rhabdomyolysis and capillary leak syndrome in a patient treated with topical imiquimod
Int J Dermatol, 55 (9), 1030-2
DOI 10.1111/ijd.13255, PubMed 27061736
High serum CXCL10 in Rickettsia conorii infection is endothelial cell mediated subsequent to whole blood activation
Cytokine, 83, 269-274
DOI 10.1016/j.cyto.2016.05.006, PubMed 27180202
Rickettsia conorii is a potent complement activator in vivo and combined inhibition of complement and CD14 is required for attenuation of the cytokine response ex vivo
Clin Microbiol Infect, 22 (8), 734.e1-6
DOI 10.1016/j.cmi.2016.05.010, PubMed 27217049
Endostatin is higher and associated with pulmonary involvement in primary Sjögren's syndrome
Clin Exp Rheumatol, 34 (4), 690-3
PubMed 27214260
NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis
J Am Heart Assoc, 5 (5)
DOI 10.1161/JAHA.115.003031, PubMed 27207962
Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis
J Immunol, 196 (12), 5064-74
DOI 10.4049/jimmunol.1502595, PubMed 27183610
Increased circulating resistin is associated with insulin resistance, oxidative stress and platelet activation in type 2 diabetes mellitus
Thromb Haemost, 116 (6), 1089-1099
DOI 10.1160/TH16-06-0471, PubMed 27709225
Circulating cell-free DNA is elevated in community-acquired bacterial pneumonia and predicts short-term outcome
J Infect, 73 (4), 383-6
DOI 10.1016/j.jinf.2016.07.011, PubMed 27452197
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis
Atherosclerosis, 247, 64-9
DOI 10.1016/j.atherosclerosis.2016.01.033, PubMed 26868510
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA
Free Radic Biol Med, 97, 386-397
DOI 10.1016/j.freeradbiomed.2016.07.001, PubMed 27381496
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice
Sci Rep, 6, 28337
DOI 10.1038/srep28337, PubMed 27328939
Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts
Biochim Biophys Acta Mol Cell Biol Lipids, 1862 (2), 234-245
DOI 10.1016/j.bbalip.2016.11.003, PubMed 27845246
A potential founder variant in CARMIL2/RLTPR in three Norwegian families with warts, molluscum contagiosum, and T-cell dysfunction
Mol Genet Genomic Med, 4 (6), 604-616
DOI 10.1002/mgg3.237, PubMed 27896283
Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders
J Allergy Clin Immunol, 139 (1), 232-245
DOI 10.1016/j.jaci.2016.05.042, PubMed 27577878
Specific allergen immunotherapy: effect on IgE, IgG4 and chemokines in patients with allergic rhinitis
Scand J Clin Lab Invest, 76 (2), 118-27
DOI 10.3109/00365513.2015.1110856, PubMed 26878875
Patterns of constitutively phosphorylated kinases in B cells are associated with disease severity in common variable immunodeficiency
Clin Immunol, 175, 69-74
DOI 10.1016/j.clim.2016.11.014, PubMed 27919819
Low levels of short- and medium-chain acylcarnitines in HIV-infected patients
Eur J Clin Invest, 46 (5), 408-17
DOI 10.1111/eci.12609, PubMed 26913383
Response to letter from Toldo et al. on "NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotective"
Biochem Biophys Res Commun, 474 (2), 328-329
DOI 10.1016/j.bbrc.2016.04.096, PubMed 27109473
Lessons Learned From a Randomized Study of Oral Valganciclovir Versus Parenteral Ganciclovir Treatment of Cytomegalovirus Disease in Solid Organ Transplant Recipients: The VICTOR Trial
Clin Infect Dis, 62 (9), 1154-60
DOI 10.1093/cid/ciw084, PubMed 26908810
Publications 2015
Interleukin 23 levels are increased in carotid atherosclerosis: possible role for the interleukin 23/interleukin 17 axis
Stroke, 46 (3), 793-9
DOI 10.1161/STROKEAHA.114.006516, PubMed 25649806
Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
PLoS One, 10 (4), e0123057
DOI 10.1371/journal.pone.0123057, PubMed 25853426
Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms
PLoS One, 10 (5), e0128048
DOI 10.1371/journal.pone.0128048, PubMed 25978331
The Effect of Everolimus Initiation and Calcineurin Inhibitor Elimination on Cardiac Allograft Vasculopathy in De Novo Recipients: One-Year Results of a Scandinavian Randomized Trial
Am J Transplant, 15 (7), 1967-75
DOI 10.1111/ajt.13214, PubMed 25783974
Secreted Frizzled Related Protein 3 in Chronic Heart Failure: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)
PLoS One, 10 (8), e0133970
DOI 10.1371/journal.pone.0133970, PubMed 26288364
Complement Activation Correlates With Disease Severity and Contributes to Cytokine Responses in Plasmodium falciparum Malaria
J Infect Dis, 212 (11), 1835-40
DOI 10.1093/infdis/jiv283, PubMed 25980034
Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice
Am J Physiol Lung Cell Mol Physiol, 309 (4), L378-87
DOI 10.1152/ajplung.00342.2014, PubMed 26071556
Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice
PLoS One, 10 (10), e0139715
DOI 10.1371/journal.pone.0139715, PubMed 26461521
Elevated inflammatory markers in preeclamptic pregnancies, but no relation to systemic arterial stiffness
Pregnancy Hypertens, 5 (4), 325-9
DOI 10.1016/j.preghy.2015.09.003, PubMed 26597749
Altered Levels of Fatty Acids and Inflammatory and Metabolic Mediators in Epicardial Adipose Tissue in Patients With Systolic Heart Failure
J Card Fail, 21 (11), 916-23
DOI 10.1016/j.cardfail.2015.07.014, PubMed 26231517
A focus on inflammation as a major risk factor for atherosclerotic cardiovascular diseases
Expert Rev Cardiovasc Ther, 14 (3), 391-403
DOI 10.1586/14779072.2016.1128828, PubMed 26641944
Increased expression of NAMPT in PBMC from patients with acute coronary syndrome and in inflammatory M1 macrophages
Atherosclerosis, 243 (1), 204-10
DOI 10.1016/j.atherosclerosis.2015.09.010, PubMed 26402139
Etiology of community-acquired pneumonia and diagnostic yields of microbiological methods: a 3-year prospective study in Norway
BMC Infect Dis, 15, 64
DOI 10.1186/s12879-015-0803-5, PubMed 25887603
Inflammatory markers are associated with general cognitive abilities in schizophrenia and bipolar disorder patients and healthy controls
Schizophr Res, 165 (2-3), 188-94
DOI 10.1016/j.schres.2015.04.004, PubMed 25956633
Association between cytokine levels, verbal memory and hippocampus volume in psychotic disorders and healthy controls
Acta Psychiatr Scand, 133 (1), 53-62
DOI 10.1111/acps.12467, PubMed 26189721
The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis
Atherosclerosis, 241 (2), 480-94
DOI 10.1016/j.atherosclerosis.2015.05.038, PubMed 26086357
IRF4 Is a Critical Gene in Retinoic Acid-Mediated Plasma Cell Formation and Is Deregulated in Common Variable Immunodeficiency-Derived B Cells
J Immunol, 195 (6), 2601-11
DOI 10.4049/jimmunol.1500250, PubMed 26276871
Body mass index influence interferon-beta treatment response in multiple sclerosis
J Neuroimmunol, 288, 92-7
DOI 10.1016/j.jneuroim.2015.09.008, PubMed 26531700
Soluble CXCL16 and risk of myocardial infarction: The HUNT study in Norway
Atherosclerosis, 244, 188-94
DOI 10.1016/j.atherosclerosis.2015.11.022, PubMed 26649903
Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors
Circ Res, 118 (1), 83-94
DOI 10.1161/CIRCRESAHA.115.306629, PubMed 26487741
Aortic Stiffness and Cardiovascular Risk in Women with Previous Gestational Diabetes Mellitus
PLoS One, 10 (8), e0136892
DOI 10.1371/journal.pone.0136892, PubMed 26309121
Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells
Nat Commun, 6, 6804
DOI 10.1038/ncomms7804, PubMed 25891430
Maternal inheritance does not predict cholesterol levels in children with familial hypercholesterolemia
Atherosclerosis, 243 (1), 155-60
DOI 10.1016/j.atherosclerosis.2015.09.014, PubMed 26386212
Serum brain-derived neurotrophic factor levels in relation to comorbid depression and cytokine levels in Nepalese men with alcohol-use disorders
Alcohol, 49 (5), 471-8
DOI 10.1016/j.alcohol.2015.01.012, PubMed 25873205
Increased Serum Levels of the Notch Ligand DLL1 are Associated with Diastolic Dysfunction, Reduced Exercise Capacity, and Adverse Outcome in Chronic Heart Failure
J Card Fail, 22 (3), 218-23
DOI 10.1016/j.cardfail.2015.07.012, PubMed 26211721
Circulating nucleosomes in chronic heart failure
Int J Cardiol, 203, 742-3
DOI 10.1016/j.ijcard.2015.10.219, PubMed 26595779
Increased Serum Levels of LIGHT/TNFSF14 in Nonalcoholic Fatty Liver Disease: Possible Role in Hepatic Inflammation
Clin Transl Gastroenterol, 6 (7), e95
DOI 10.1038/ctg.2015.23, PubMed 26133108
Vitamin D, vitamin D binding protein, and longitudinal outcomes in COPD
PLoS One, 10 (3), e0121622
DOI 10.1371/journal.pone.0121622, PubMed 25803709
High MIP-1β Levels in Plasma Predict Long-Term Immunological Nonresponse to Suppressive Antiretroviral Therapy in HIV Infection
J Acquir Immune Defic Syndr, 69 (4), 395-402
DOI 10.1097/QAI.0000000000000617, PubMed 26115437
Associations between circulating endostatin levels and vascular organ damage in systemic sclerosis and mixed connective tissue disease: an observational study
Arthritis Res Ther, 17 (1), 231
DOI 10.1186/s13075-015-0756-5, PubMed 26315510
Vitamin D status and effect of interferon-β1a treatment on MRI activity and serum inflammation markers in relapsing-remitting multiple sclerosis
J Neuroimmunol, 280, 21-8
DOI 10.1016/j.jneuroim.2015.02.001, PubMed 25773151
Vitamin D supplementation and systemic inflammation in relapsing-remitting multiple sclerosis
J Neurol, 262 (12), 2713-21
DOI 10.1007/s00415-015-7902-5, PubMed 26429571
NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotective
Biochem Biophys Res Commun, 469 (4), 1012-20
DOI 10.1016/j.bbrc.2015.12.051, PubMed 26706279
Circulating annexin A5 predicts mortality in patients with heart failure
J Intern Med, 279 (1), 89-97
DOI 10.1111/joim.12396, PubMed 26223343
Genetic variants in the DNA repair gene NEIL3 and the risk of myocardial infarction in a nested case-control study. The HUNT Study
DNA Repair (Amst), 28, 21-7
DOI 10.1016/j.dnarep.2015.01.013, PubMed 25703835
Circulating levels of inflammatory cytokines and cytokine receptors in patients with ankylosing spondylitis: a cross-sectional comparative study
Scand J Rheumatol, 44 (2), 118-24
DOI 10.3109/03009742.2014.956142, PubMed 25756521
Secreted Frizzled-Related Protein 3 (sFRP3) in acute coronary syndromes
Int J Cardiol, 190, 217-9
DOI 10.1016/j.ijcard.2015.03.401, PubMed 25920031
Increased osteoprotegerin predicts poor virological outcome during anticytomegalovirus therapy in solid organ transplant recipients
Transplantation, 99 (1), 100-5
DOI 10.1097/TP.0000000000000227, PubMed 24983306
IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy
J Infect, 70 (4), 381-91
DOI 10.1016/j.jinf.2014.12.019, PubMed 25597826
Myocardial Function by Two-Dimensional Speckle Tracking Echocardiography and Activin A May Predict Mortality in Patients with Carcinoid Intestinal Disease
Cardiology, 132 (2), 81-90
DOI 10.1159/000431076, PubMed 26111973
Publications 2014
Matrix metalloproteinase 7 is associated with symptomatic lesions and adverse events in patients with carotid atherosclerosis
PLoS One, 9 (1), e84935
DOI 10.1371/journal.pone.0084935, PubMed 24400123
The Notch ligand Delta-like 1 is elevated and associated with mortality in patients with symptomatic aortic stenosis
Int J Cardiol, 180, 18-20
DOI 10.1016/j.ijcard.2014.11.111, PubMed 25438200
Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes
Hypertension, 63 (4), 819-26
DOI 10.1161/HYPERTENSIONAHA.113.02077, PubMed 24396023
The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure
J Intern Med, 275 (6), 621-30
DOI 10.1111/joim.12175, PubMed 24330105
Interleukin-6 signaling, soluble glycoprotein 130, and inflammation in heart failure
Curr Heart Fail Rep, 11 (2), 146-55
DOI 10.1007/s11897-014-0185-9, PubMed 24477903
Cytokine network in scrub typhus: high levels of interleukin-8 are associated with disease severity and mortality
PLoS Negl Trop Dis, 8 (2), e2648
DOI 10.1371/journal.pntd.0002648, PubMed 24516677
Increased expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental Rickettsia conorii infection
BMC Infect Dis, 14, 70
DOI 10.1186/1471-2334-14-70, PubMed 24507453
Increased severity and mortality in adults co-infected with malaria and HIV in Maputo, Mozambique: a prospective cross-sectional study
PLoS One, 9 (2), e88257
DOI 10.1371/journal.pone.0088257, PubMed 24505451
Cytokine network in adults with falciparum Malaria and HIV-1: increased IL-8 and IP-10 levels are associated with disease severity
PLoS One, 9 (12), e114480
DOI 10.1371/journal.pone.0114480, PubMed 25503583
Soluble ST2 reflects hemodynamic stress in non-ischemic heart failure
Int J Cardiol, 179, 378-84
DOI 10.1016/j.ijcard.2014.11.003, PubMed 25464491
The effect of rosuvastatin on inflammation, matrix turnover and left ventricular remodeling in dilated cardiomyopathy: a randomized, controlled trial
PLoS One, 9 (2), e89732
DOI 10.1371/journal.pone.0089732, PubMed 24586994
Association between altered brain morphology and elevated peripheral endothelial markers--implications for psychotic disorders
Schizophr Res, 161 (2-3), 222-8
DOI 10.1016/j.schres.2014.11.006, PubMed 25433965
The homeostatic chemokine CCL21 predicts mortality in aortic stenosis patients and modulates left ventricular remodeling
PLoS One, 9 (11), e112172
DOI 10.1371/journal.pone.0112172, PubMed 25398010
Plasma NGAL and glomerular filtration rate in cardiac transplant recipients treated with standard or reduced calcineurin inhibitor levels
Biomark Med, 8 (2), 239-45
DOI 10.2217/bmm.13.95, PubMed 24521021
Increased levels of CCR7 ligands in carotid atherosclerosis: different effects in macrophages and smooth muscle cells
Cardiovasc Res, 102 (1), 148-56
DOI 10.1093/cvr/cvu036, PubMed 24518141
Interleukin-10 increases reverse cholesterol transport in macrophages through its bidirectional interaction with liver X receptor α
Biochem Biophys Res Commun, 450 (4), 1525-30
DOI 10.1016/j.bbrc.2014.07.036, PubMed 25035925
Activated platelets promote increased monocyte expression of CXCR5 through prostaglandin E2-related mechanisms and enhance the anti-inflammatory effects of CXCL13
Atherosclerosis, 234 (2), 352-9
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Novel extracellular matrix biomarkers as predictors of adverse outcome in chronic heart failure: association between biglycan and response to statin therapy in the CORONA trial
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Predictive value of endostatin in chronic heart failure patients with poor kidney function
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Prognostic value of CXCL16 in patients with left ventricular systolic dysfunction and heart failure
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Increased systemic and local interleukin 9 levels in patients with carotid and coronary atherosclerosis
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Lung disease, T-cells and inflammation in common variable immunodeficiency disorders
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Inflammation markers in multiple sclerosis: CXCL16 reflects and may also predict disease activity
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Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
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Interleukin 1 receptor antagonist and soluble tumor necrosis factor receptor 1 are associated with general severity and psychotic symptoms in schizophrenia and bipolar disorder
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Retinoic acid improves defective TLR9/RP105-induced immune responses in common variable immunodeficiency-derived B cells
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Single-nucleotide polymorphisms in Toll-like receptor (TLR)-2, TLR4 and heat shock protein 70 genes and susceptibility to scrub typhus
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Cardiac resynchronization therapy improves minute ventilation/carbon dioxide production slope and skeletal muscle capillary density without reversal of skeletal muscle pathology or inflammation
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Intestinal Kaposi sarcoma in a lung transplant recipient: therapy with mammalian target of rapamycin inhibitor and immunosuppression reduction
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The relationship between markers of extracellular cardiac matrix turnover: infarct healing and left ventricular remodelling following primary PCI in patients with first-time STEMI
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Low level of inflammatory marker in hyperhomocysteinemic patients on statin therapy
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Inflammatory cytokines in chronic heart failure: interleukin-8 is associated with adverse outcome. Results from CORONA
Eur J Heart Fail, 16 (1), 68-75
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Effect of high-intensity interval training on progression of cardiac allograft vasculopathy
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Interleukin-6 and activin A are independently associated with cardiovascular events and mortality in type 2 diabetes: the prospective Asker and Bærum Cardiovascular Diabetes (ABCD) cohort study
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Association of ficolin-3 with severity and outcome of chronic heart failure
PLoS One, 8 (4), e60976
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Characterization of cytomegalovirus disease in solid organ transplant recipients by markers of inflammation in plasma
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The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury
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CCL21 is associated with fatal outcomes in chronic heart failure: data from CORONA and GISSI-HF trials
Eur J Heart Fail, 15 (7), 747-55
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Secreted Wnt antagonists during eradication of cytomegalovirus infection in solid organ transplant recipients
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Prognostic value of changes in galectin-3 levels over time in patients with heart failure: data from CORONA and COACH
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An immunomodulating fatty acid analogue targeting mitochondria exerts anti-atherosclerotic effect beyond plasma cholesterol-lowering activity in apoe(-/-) mice
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De novo 19p13.2 microdeletion encompassing the insulin receptor and resistin genes in a patient with obesity and learning disability
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Differences in insulin sensitivity, lipid metabolism and inflammation between young adult Pakistani and Norwegian patients with type 2 diabetes: a cross sectional study
BMC Endocr Disord, 13, 49
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Publications 2012
High levels of S100A12 are associated with recent plaque symptomatology in patients with carotid atherosclerosis
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Virtual histology assessment of cardiac allograft vasculopathy following introduction of everolimus--results of a multicenter trial
Am J Transplant, 12 (10), 2700-9
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Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: the significance of baseline glomerular filtration rate
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DOI 10.1016/j.healun.2011.12.010, PubMed 22333403
Peak oxygen uptake during cardiopulmonary exercise testing determines response to cardiac resynchronization therapy
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Secreted Wnt modulators in symptomatic aortic stenosis
J Am Heart Assoc, 1 (6), e002261
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Soluble glycoprotein 130 predicts fatal outcomes in chronic heart failure: analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)
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A complex interaction between Rickettsia conorii and Dickkopf-1--potential role in immune evasion mechanisms in endothelial cells
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Increased circulating mitochondrial DNA after myocardial infarction
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NT-proBNP predicts myocardial recovery after non-ST-elevation acute coronary syndrome
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Soluble ST2 is associated with adverse outcome in patients with heart failure of ischaemic aetiology
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Heart failure biomarkers: focus on interleukin-1 receptor-like 1-based blood tests
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Unraveling the role of nicotinamide phosphoribosyltransferase on lipids in atherosclerosis
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Visfatin/NAMPT: a multifaceted molecule with diverse roles in physiology and pathophysiology
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Serum levels of neutrophil gelatinase-associated lipocalin are associated with microalbuminuria in HIV-infected patients
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Enhanced levels of CCL19 in patients with advanced acquired immune deficiency syndrome (AIDS)
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Up-regulation of NOTCH4 gene expression in bipolar disorder
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Cardiovascular risk factors during second generation antipsychotic treatment are associated with increased C-reactive protein
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Intravenous immunoglobulin does not reduce left ventricular remodeling in patients with myocardial dysfunction during hospitalization after acute myocardial infarction
Int J Cardiol, 168 (1), 212-8
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Galectin-3 predicts response to statin therapy in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)
Eur Heart J, 33 (18), 2290-6
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The predictive value of galectin-3 for mortality and cardiovascular events in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)
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Inflammatory cytokines in heart failure: mediators and markers
Cardiology, 122 (1), 23-35
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Visfatin/NAMPT - a hot spot in thrombosis?
Thromb Res, 130 (3), 289-90
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Statins affect the presentation of endothelial chemokines by targeting to multivesicular bodies
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Multimarker risk assessment including osteoprotegerin and CXCL16 in acute coronary syndromes
Arterioscler Thromb Vasc Biol, 32 (12), 3041-9
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Highly sensitive troponin T in patients with acute ischemic stroke
Eur Neurol, 68 (5), 287-93
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Pentraxin-3 in chronic heart failure: the CORONA and GISSI-HF trials
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Plasma levels of soluble CD36, platelet activation, inflammation, and oxidative stress are increased in type 2 diabetic patients
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Oxidized LDL level is related to gene expression of tumour necrosis factor super family members in children and young adults with familial hypercholesterolaemia
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Maternal familial hypercholesterolaemia (FH) confers altered haemostatic profile in offspring with and without FH
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LDL-apheresis affects markers of endothelial function in patients with homozygous familial hypercholesterolemia
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Cholesterol efflux mediators in homozygous familial hypercholesterolemia patients on low-density lipoprotein apheresis
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Elevated serum MMP-9/TIMP-1 ratio in patients with homozygous familial hypercholesterolemia: effects of LDL-apheresis
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The association between neutrophil gelatinase-associated lipocalin and clinical outcome in chronic heart failure: results from CORONA*
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High-intensity interval training improves peak oxygen uptake and muscular exercise capacity in heart transplant recipients
Am J Transplant, 12 (11), 3134-42
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Adipocytes as a source of increased circulating levels of nicotinamide phosphoribosyltransferase/visfatin in active acromegaly
J Clin Endocrinol Metab, 97 (4), 1355-62
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The prediction of adverse cardiac remodelling following myocardial infarction: defining the need for a dynamic multimarker approach
Heart, 98 (15), 1112-3
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Treatment of cytomegalovirus disease in solid organ transplant recipients: markers of inflammation as predictors of outcome
Transplantation, 94 (10), 1060-5
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Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis
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Increased levels of inflammatory cytokines and endothelin-1 in alveolar macrophages from patients with chronic heart failure
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Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis - Potential role in plaque stabilization
Atherosclerosis, 224 (1), 266-73
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High-sensitive troponin T and N-terminal-brain-natriuretic-peptide predict outcome in symptomatic aortic stenosis
Scand Cardiovasc J, 46 (5), 278-85
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Activin A and cardiovascular disease in type 2 diabetes mellitus
Diab Vasc Dis Res, 9 (3), 234-7
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Disturbed carnitine regulation in chronic heart failure--increased plasma levels of palmitoyl-carnitine are associated with poor prognosis
Int J Cardiol, 167 (5), 1892-9
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TNF revisited: osteoprotegerin and TNF-related molecules in heart failure
Curr Heart Fail Rep, 9 (2), 92-100
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Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
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Different COPD disease characteristics are related to different outcomes in the 6-minute walk test
COPD, 9 (3), 227-34
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The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure
PLoS One, 7 (3), e33038
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Tetradecylthioacetic acid increases fat metabolism and improves cardiac function in experimental heart failure
Lipids, 48 (2), 139-54
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Increased interleukin-1β levels are associated with left ventricular hypertrophy and remodelling following acute ST segment elevation myocardial infarction treated by primary percutaneous coronary intervention
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Publications 2011
Elevated serum osteoprotegerin levels measured early after acute ST-elevation myocardial infarction predict final infarct size
Heart, 97 (6), 460-5
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Activin A levels are associated with abnormal glucose regulation in patients with myocardial infarction: potential counteracting effects of activin A on inflammation
Diabetes, 60 (5), 1544-51
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Effect of everolimus introduction on cardiac allograft vasculopathy--results of a randomized, multicenter trial
Transplantation, 92 (2), 235-43
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Excessive innate immune response and mutant D222G/N in severe A (H1N1) pandemic influenza
J Infect, 63 (4), 308-16
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No inflammatory response related to pulmonary hemodynamics in children with systemic to pulmonary shunts
Congenit Heart Dis, 6 (4), 338-46
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Nicotinamide phosphoribosyltransferase and lipid accumulation in macrophages
Eur J Clin Invest, 41 (10), 1098-104
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Plasmacytoid dendritic cells protect against atherosclerosis by tuning T-cell proliferation and activity
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Krill oil attenuates left ventricular dilatation after myocardial infarction in rats
Lipids Health Dis, 10, 245
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Antibodies to common infectious agents in coronary artery disease patients with and without rheumatic conditions
Rheumatology (Oxford), 51 (4), 679-85
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Fetuin A in nonalcoholic fatty liver disease: in vivo and in vitro studies
Eur J Endocrinol, 166 (3), 503-10
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Fatty Acid binding protein 4 is associated with carotid atherosclerosis and outcome in patients with acute ischemic stroke
PLoS One, 6 (12), e28785
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Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia
J Psychiatr Res, 45 (12), 1608-16
DOI 10.1016/j.jpsychires.2011.08.003, PubMed 21889167
Persistently raised plasma levels of platelet-derived inflammatory mediators in HIV-infected patients during highly active anti-retroviral therapy
J Thromb Haemost, 9 (5), 1075-7
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Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation
Am J Physiol Lung Cell Mol Physiol, 301 (1), L50-9
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Clustering of 37 circulating biomarkers by exploratory factor analysis in patients following complicated acute myocardial infarction
Int J Cardiol, 166 (3), 729-35
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Anti-inflammatory and hypolipidemic effects of the modified fatty acid tetradecylthioacetic acid in psoriasis--a pilot study
Scand J Clin Lab Invest, 71 (4), 269-73
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Inflammatory response to percutaneous coronary intervention in stable coronary artery disease
J Thromb Thrombolysis, 31 (1), 92-8
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High intensity interval training reduces systemic inflammation in post-PCI patients
Eur J Cardiovasc Prev Rehabil, 18 (6), 850-7
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Higher levels of fatigue are associated with higher CRP levels in disease-free breast cancer survivors
J Psychosom Res, 71 (3), 136-41
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Explained variance for blood gases in a population with COPD
Clin Respir J, 6 (2), 72-80
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Activated leukocyte cell adhesion molecule and prognosis in acute ischemic stroke
Stroke, 42 (9), 2453-8
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Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis
Br J Dermatol, 164 (2), 344-55
DOI 10.1111/j.1365-2133.2010.10149.x, PubMed 21271993
Galectin-3 in heart failure: high levels are associated with all-cause mortality
Int J Cardiol, 150 (3), 361-4
DOI 10.1016/j.ijcard.2011.05.081, PubMed 21641051
Osteoprotegerin levels predict mortality in patients with symptomatic aortic stenosis
J Intern Med, 270 (5), 452-60
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Effect of eptifibatide on platelet-mediated inflammation in acute coronary syndromes
Int J Cardiol, 151 (3), 385-7
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Circulating levels of non-phosphorylated undercarboxylated matrix Gla protein are associated with disease severity in patients with chronic heart failure
Clin Sci (Lond), 121 (3), 119-27
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Osteoprotegerin predicts progression of chronic heart failure: results from CORONA
Circ Heart Fail, 4 (2), 145-52
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Interleukin 1 receptor antagonist is associated with changes in body composition during physiological GH substitution in patients with adult-onset growth hormone deficiency
Clin Endocrinol (Oxf), 74 (1), 60-6
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Increased serum and bone matrix levels of transforming growth factor {beta}1 in patients with GH deficiency in response to GH treatment
Eur J Endocrinol, 165 (3), 393-400
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Soluble CXCL16 and long-term outcome in acute ischemic stroke
Atherosclerosis, 220 (1), 244-9
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Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload
PLoS One, 6 (4), e18668
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Activin A in nonalcoholic fatty liver disease
Vitam Horm, 85, 323-42
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Fatty acid composition in chronic heart failure: low circulating levels of eicosatetraenoic acid and high levels of vaccenic acid are associated with disease severity and mortality
J Intern Med, 270 (3), 263-72
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Prognostic value of cardiac troponin T in patients with moderate to severe heart failure scheduled for cardiac resynchronization therapy
Am Heart J, 161 (6), 1031-7
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Publications 2010
Systemic markers of inflammation are associated with cardiac allograft vasculopathy and an increased intimal inflammatory component
Am J Transplant, 10 (6), 1428-36
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Activated platelets and atherosclerosis
Expert Rev Cardiovasc Ther, 8 (9), 1297-307
DOI 10.1586/erc.10.92, PubMed 20828352
Tumor necrosis factor superfamily molecules in acute coronary syndromes
Ann Med, 43 (2), 90-103
DOI 10.3109/07853890.2010.523711, PubMed 21039303
Inadequate Masking of Testosterone Reply
J. Am. Coll. Cardiol., 55 (20), 2291
DOI 10.1016/j.jacc.2009.10.083
Osteoprotegrin and soluble tumor necrosis factor receptor 1 are associated with microalbuminuria in nontreated HIV-infected patients
J Acquir Immune Defic Syndr, 53 (3), 419-20
DOI 10.1097/QAI.0b013e3181ba4101, PubMed 20190590
Activin A in carcinoid heart disease: a possible role in diagnosis and pathogenesis
Neuroendocrinology, 92 (3), 168-77
DOI 10.1159/000318014, PubMed 20720391
Plasma CCN2/connective tissue growth factor is associated with right ventricular dysfunction in patients with neuroendocrine tumors
BMC Cancer, 10, 6
DOI 10.1186/1471-2407-10-6, PubMed 20053285
Inflammatory markers in patients with coronary artery disease with and without inflammatory rheumatic disease
Rheumatology (Oxford), 49 (6), 1118-27
DOI 10.1093/rheumatology/keq005, PubMed 20231178
Raised MCP-4 levels in symptomatic carotid atherosclerosis: an inflammatory link between platelet and monocyte activation
Cardiovasc Res, 86 (2), 265-73
DOI 10.1093/cvr/cvq044, PubMed 20139115
Osteoprotegerin: a biomarker with many faces
Arterioscler Thromb Vasc Biol, 30 (9), 1684-6
DOI 10.1161/ATVBAHA.110.208843, PubMed 20720194
Intracellular nicotinamide phosphoribosyltransferase protects against hepatocyte apoptosis and is down-regulated in nonalcoholic fatty liver disease
J Clin Endocrinol Metab, 95 (6), 3039-47
DOI 10.1210/jc.2009-2148, PubMed 20392873
Systemic mannose-binding lectin is not associated with Chronic Obstructive Pulmonary Disease
Respir Med, 104 (2), 283-90
DOI 10.1016/j.rmed.2009.09.015, PubMed 19836222
Body composition and plasma levels of inflammatory biomarkers in COPD
Eur Respir J, 36 (5), 1027-33
DOI 10.1183/09031936.00194209, PubMed 20413541
Neutrophil gelatinase-associated lipocalin: a biomarker in COPD
Chest, 138 (4), 888-95
DOI 10.1378/chest.09-2718, PubMed 20495108
Treatment of Schnitzler's syndrome with anakinra: report of three cases and review of the literature
Scand J Rheumatol, 40 (1), 74-9
DOI 10.3109/03009742.2010.493894, PubMed 20936987
Development of pulmonary abnormalities in patients with common variable immunodeficiency: associations with clinical and immunologic factors
Ann Allergy Asthma Immunol, 104 (6), 503-10
DOI 10.1016/j.anai.2010.04.015, PubMed 20568383
The peripheral blood mononuclear cell microRNA signature of coronary artery disease
Biochem Biophys Res Commun, 394 (3), 792-7
DOI 10.1016/j.bbrc.2010.03.075, PubMed 20230787
Osteoprotegerin levels in patients with severe mental disorders
J Psychiatry Neurosci, 35 (5), 304-10
DOI 10.1503/jpn.090088, PubMed 20569643
Osteoprotegerin and acute ischaemic stroke: reply
J. Intern. Med., 267 (4), 437
DOI 10.1111/j.1365-2796.2009.02170.x
Increased YKL-40 expression in patients with carotid atherosclerosis
Atherosclerosis, 211 (2), 589-95
DOI 10.1016/j.atherosclerosis.2010.02.035, PubMed 20347092
Children with familial hypercholesterolemia are characterized by an inflammatory imbalance between the tumor necrosis factor α system and interleukin-10
Atherosclerosis, 214 (1), 163-8
DOI 10.1016/j.atherosclerosis.2010.10.002, PubMed 21040915
Serum osteoprotegerin levels and long-term prognosis in patients with stable angina pectoris
Atherosclerosis, 212 (2), 644-9
DOI 10.1016/j.atherosclerosis.2010.06.027, PubMed 20621297
Undercarboxylated matrix Gla protein is associated with indices of heart failure and mortality in symptomatic aortic stenosis
J Intern Med, 268 (5), 483-92
DOI 10.1111/j.1365-2796.2010.02264.x, PubMed 20804515
C-reactive protein; a potential marker of second cancer and cardiovascular disease in testicular cancer survivors?
Eur J Cancer, 46 (18), 3425-33
DOI 10.1016/j.ejca.2010.08.004, PubMed 20832295
Adrenomedullin is increased in alveolar macrophages and released from the lungs into the circulation in severe heart failure
Basic Res Cardiol, 105 (1), 89-98
DOI 10.1007/s00395-009-0070-y, PubMed 19823891
Activation of Notch signaling in cardiomyocytes during post-infarction remodeling
Scand Cardiovasc J, 44 (6), 359-66
DOI 10.3109/14017431.2010.511256, PubMed 20799913
Publications 2009
The prognostic importance of modifiable risk factors after heart transplantation
Am Heart J, 158 (3), 431-6
DOI 10.1016/j.ahj.2009.05.036, PubMed 19699867
Elevated serum uric acid levels following heart transplantation predict all-cause and cardiac mortality
Eur J Heart Fail, 11 (10), 1005-13
DOI 10.1093/eurjhf/hfp115, PubMed 19737803
Testosterone: a novel therapeutic approach in chronic heart failure?
J Am Coll Cardiol, 54 (10), 928-9
DOI 10.1016/j.jacc.2009.05.039, PubMed 19712803
Patients with pulmonary hypertension related to congenital systemic-to-pulmonary shunts are characterized by inflammation involving endothelial cell activation and platelet-mediated inflammation
Congenit Heart Dis, 4 (3), 153-9
DOI 10.1111/j.1747-0803.2009.00297.x, PubMed 19489942
Increased production of CXCL16 in experimental and clinical heart failure: a possible role in extracellular matrix remodeling
Circ Heart Fail, 2 (6), 624-32
DOI 10.1161/CIRCHEARTFAILURE.108.821074, PubMed 19919988
Enhanced levels of the CCR7 ligands CCL19 and CCL21 in HIV infection: correlation with viral load, disease progression and response to highly active antiretroviral therapy
AIDS, 23 (1), 135-8
DOI 10.1097/QAD.0b013e32831cf595, PubMed 19050397
Homeostatic chemokines CCL19 and CCL21 promote inflammation in human immunodeficiency virus-infected patients with ongoing viral replication
Clin Exp Immunol, 157 (3), 400-7
DOI 10.1111/j.1365-2249.2009.03976.x, PubMed 19664149
Impaired effector memory T-cell regulation facilitates graft versus host disease in CCR7-deficient bone marrow transplant chimeras
Transplantation, 88 (5), 631-9
DOI 10.1097/TP.0b013e3181b241df, PubMed 19741459
Systemic inflammatory markers in COPD: results from the Bergen COPD Cohort Study
Eur Respir J, 35 (3), 540-8
DOI 10.1183/09031936.00088209, PubMed 19643942
Perfusion temperature, thyroid hormones and inflammation during pediatric cardiac surgery
Interact Cardiovasc Thorac Surg, 10 (1), 76-80
DOI 10.1510/icvts.2009.213876, PubMed 19822605
Enhanced levels of urokinase plasminogen activator and its soluble receptor in common variable immunodeficiency
Clin Immunol, 131 (3), 438-46
DOI 10.1016/j.clim.2009.01.007, PubMed 19232508
Chemokines and common variable immunodeficiency; possible contribution of CCL19, CCL21 and CCR7 to immune dysregulation
Clin Exp Immunol, 158 (2), 237-45
DOI 10.1111/j.1365-2249.2009.04013.x, PubMed 19747210
High resolution computed tomography and pulmonary function in common variable immunodeficiency
Respir Med, 103 (6), 873-80
DOI 10.1016/j.rmed.2008.12.015, PubMed 19181508
Treatment with the PPARgamma agonist rosiglitazone downregulates interleukin-1 receptor antagonist in individuals with metabolic syndrome
Eur J Endocrinol, 162 (2), 267-73
DOI 10.1530/EJE-09-0706, PubMed 19926782
Depression has a Strong Relationship to Alterations in the Immune, Endocrine and Neural System
Curr. Psychiatry Rev., 5 (4), 287-297
DOI 10.2174/157340009789542105
Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology
Eur J Heart Fail, 11 (2), 119-29
DOI 10.1093/eurjhf/hfn043, PubMed 19168509
Inflammatory mediators in morbidly obese subjects: associations with glucose abnormalities and changes after oral glucose
Eur J Endocrinol, 161 (3), 451-8
DOI 10.1530/EJE-09-0421, PubMed 19542241
Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor
Bipolar Disord, 11 (7), 726-34
DOI 10.1111/j.1399-5618.2009.00757.x, PubMed 19839997
Soluble CXCL16 predicts long-term mortality in acute coronary syndromes
Circulation, 119 (25), 3181-8
DOI 10.1161/CIRCULATIONAHA.108.806877, PubMed 19528340
Osteoprotegerin concentrations and prognosis in acute ischaemic stroke
J Intern Med, 267 (4), 410-7
DOI 10.1111/j.1365-2796.2009.02163.x, PubMed 19895657
Diabetic foot ulcer burden may be modified by high-dose atorvastatin: A 6-month randomized controlled pilot trial
J Diabetes, 1 (3), 182-7
DOI 10.1111/j.1753-0407.2009.00031.x, PubMed 20923537
Elevated visfatin levels in overweight and obese children and adolescents with metabolic syndrome
Scand J Clin Lab Invest, 69 (8), 858-64
DOI 10.3109/00365510903348677, PubMed 19929281
A helicopter flight does not induce significant changes in systemic biomarker profiles
Scand J Clin Lab Invest, 69 (4), 462-74
DOI 10.1080/00365510902745360, PubMed 19333819
CXCL16 in HIV infection - a link between inflammation and viral replication
Eur J Clin Invest, 39 (11), 1017-24
DOI 10.1111/j.1365-2362.2009.02207.x, PubMed 19674076
The chemokine network in relation to infarct size and left ventricular remodeling following acute myocardial infarction
Am J Cardiol, 104 (9), 1179-83
DOI 10.1016/j.amjcard.2009.06.028, PubMed 19840558
Levels of circulating interleukin-1 receptor antagonist and C-reactive protein in long-term survivors of testicular cancer with chronic cancer-related fatigue
Brain Behav Immun, 23 (6), 868-74
DOI 10.1016/j.bbi.2009.04.003, PubMed 19362138
Activation of platelets by Aspergillus fumigatus and potential role of platelets in the immunopathogenesis of Aspergillosis
Infect Immun, 78 (3), 1269-75
DOI 10.1128/IAI.01091-09, PubMed 20008537
IL-10 enhances MD-2 and CD14 expression in monocytes and the proteins are increased and correlated in HIV-infected patients
J Immunol, 182 (1), 588-95
DOI 10.4049/jimmunol.182.1.588, PubMed 19109192
The tumour necrosis factor superfamily ligand APRIL (TNFSF13) is released upon platelet activation and expressed in atherosclerosis
Thromb Haemost, 102 (4), 704-10
DOI 10.1160/TH08-10-0665, PubMed 19806256
Osteoprotegerin and soluble receptor activator of nuclear factor-kappaB ligand and risk for coronary events: a nested case-control approach in the prospective EPIC-Norfolk population study 1993-2003
Arterioscler Thromb Vasc Biol, 29 (6), 975-80
DOI 10.1161/ATVBAHA.109.184101, PubMed 19325145
Occupational exposure to bacterial single cell protein induces inflammation in lung and blood
Inhal Toxicol, 21 (8), 674-81
DOI 10.1080/08958370802491425, PubMed 19558225
Cystatin C levels in plasma and peripheral blood mononuclear cells among hyperhomocysteinaemic subjects: effect of treatment with B-vitamins
Br J Nutr, 102 (12), 1783-9
DOI 10.1017/S0007114509991048, PubMed 19682403
Associations between body composition, circulating interleukin-1 receptor antagonist, osteocalcin, and insulin metabolism in active acromegaly
J Clin Endocrinol Metab, 95 (1), 361-8
DOI 10.1210/jc.2009-0422, PubMed 19880791
Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis
Arterioscler Thromb Vasc Biol, 29 (8), 1228-34
DOI 10.1161/ATVBAHA.109.189761, PubMed 19498175
A complex role of activin A in non-alcoholic fatty liver disease
Am J Gastroenterol, 104 (9), 2196-205
DOI 10.1038/ajg.2009.318, PubMed 19532130
Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure
Eur Heart J, 30 (10), 1229-36
DOI 10.1093/eurheartj/ehp088, PubMed 19329498
Elevated levels of activin A in clinical and experimental pulmonary hypertension
J Appl Physiol (1985), 106 (4), 1356-64
DOI 10.1152/japplphysiol.90719.2008, PubMed 19196915
Up-regulation of myocardial DNA base excision repair activities in experimental heart failure
Mutat Res, 666 (1-2), 32-8
DOI 10.1016/j.mrfmmm.2009.03.008, PubMed 19481677
C-reactive protein, infarct size, microvascular obstruction, and left-ventricular remodelling following acute myocardial infarction
Eur Heart J, 30 (10), 1180-6
DOI 10.1093/eurheartj/ehp070, PubMed 19299430
Publications 2008
Chemokines and cardiovascular risk
Arterioscler Thromb Vasc Biol, 28 (11), 1909-19
DOI 10.1161/ATVBAHA.107.161240, PubMed 18669888
The complex role of T-cell-based immunity in atherosclerosis
Curr Atheroscler Rep, 10 (3), 236-43
DOI 10.1007/s11883-008-0037-8, PubMed 18489852
Exercise training decreases plasma levels of soluble CD40 ligand and P-selectin in patients with chronic heart failure
Eur J Cardiovasc Prev Rehabil, 15 (1), 43-8
DOI 10.1097/HJR.0b013e3281ca7023, PubMed 18277184
A potential role of the CXC chemokine GROalpha in atherosclerosis and plaque destabilization: downregulatory effects of statins
Arterioscler Thromb Vasc Biol, 28 (5), 1005-11
DOI 10.1161/ATVBAHA.108.162305, PubMed 18276907
Inhibition of protein kinase A improves effector function of monocytes from HIV-infected patients
AIDS Res Hum Retroviruses, 24 (7), 1013-5
DOI 10.1089/aid.2008.0071, PubMed 18593346
Increased expression of LIGHT/TNFSF14 and its receptors in experimental and clinical heart failure
Eur J Heart Fail, 10 (4), 352-9
DOI 10.1016/j.ejheart.2008.02.010, PubMed 18353719
Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever
J Infect, 58 (1), 68-75
DOI 10.1016/j.jinf.2008.11.008, PubMed 19091423
Effect of perfusion temperature on the inflammatory response during pediatric cardiac surgery
Ann Thorac Surg, 85 (2), 611-7
DOI 10.1016/j.athoracsur.2007.10.062, PubMed 18222275
Chemokines and common variable immunodeficiency; possible contribution of the fractalkine system (CX3CL1/CX3CR1) to chronic inflammation
Clin Immunol, 130 (2), 151-61
DOI 10.1016/j.clim.2008.09.002, PubMed 18938112
Atherosclerotic plaque stability--what determines the fate of a plaque?
Prog Cardiovasc Dis, 51 (3), 183-94
DOI 10.1016/j.pcad.2008.09.001, PubMed 19026853
Smoking and Inflammation: Their Synergistic Roles in Chronic Disease
Curr. Cardiovascu. Risk Rep., 2 (6), 446-451
DOI 10.1007/s12170-008-0079-z
Soluble CD36 in plasma is increased in patients with symptomatic atherosclerotic carotid plaques and is related to plaque instability
Stroke, 39 (11), 3092-5
DOI 10.1161/STROKEAHA.108.517128, PubMed 18723424
Early treatment of tetanus-induced trismus with botulinum toxin A
Anesth Analg, 106 (5), 1591
DOI 10.1213/ANE.0b013e31816a30f0, PubMed 18420892
The antiatherogenic function of HDL is impaired in hyperhomocysteinemic subjects
J Nutr, 138 (11), 2070-5
DOI 10.3945/jn.108.090704, PubMed 18936200
Cytokine expression profiling of the myocardium reveals a role for CX3CL1 (fractalkine) in heart failure
J Mol Cell Cardiol, 45 (2), 261-9
DOI 10.1016/j.yjmcc.2008.05.009, PubMed 18585734
Biochemical markers for cardiovascular risk following treatment in endogenous Cushing's syndrome
J Endocrinol Invest, 31 (5), 400-5
DOI 10.1007/BF03346383, PubMed 18560257
Decreased serum lipocalin-2 levels in human immunodeficiency virus-infected patients: increase during highly active anti-retroviral therapy
Clin Exp Immunol, 152 (1), 57-63
DOI 10.1111/j.1365-2249.2008.03592.x, PubMed 18241231
Dysregulated RANK ligand/RANK axis in hyperhomocysteinemic subjects: effect of treatment with B-vitamins
Stroke, 40 (1), 241-7
DOI 10.1161/STROKEAHA.108.522995, PubMed 19008470
CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice
Circulation, 117 (10), 1292-301
DOI 10.1161/CIRCULATIONAHA.107.699173, PubMed 18285570
Circulating osteoprotegerin levels and long-term prognosis in patients with acute coronary syndromes
J Am Coll Cardiol, 51 (6), 627-33
DOI 10.1016/j.jacc.2007.09.058, PubMed 18261681
Interleukin-6 may predict survival in extracorporeal membrane oxygenation treatment
Perfusion, 23 (3), 173-8
DOI 10.1177/0267659108097882, PubMed 19029268
Base excision repair activities in organotypic hippocampal slice cultures exposed to oxygen and glucose deprivation
DNA Repair (Amst), 7 (6), 869-78
DOI 10.1016/j.dnarep.2008.02.009, PubMed 18406215
Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis
Circ Res, 104 (1), 60-8
DOI 10.1161/CIRCRESAHA.108.188078, PubMed 19023130
High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins
Cardiovasc Res, 79 (1), 195-203
DOI 10.1093/cvr/cvn071, PubMed 18339644
Inflammatory responses after intracoronary injection of autologous mononuclear bone marrow cells in patients with acute myocardial infarction
Am Heart J, 155 (1), 55.e1-9
DOI 10.1016/j.ahj.2007.10.005, PubMed 18082489
Publications 2007
Pre-transplant Toxoplasma gondii seropositivity among heart transplant recipients is associated with an increased risk of all-cause and cardiac mortality
J Am Coll Cardiol, 50 (20), 1967-72
DOI 10.1016/j.jacc.2007.07.068, PubMed 17996562
Potential mechanisms of benefit with thalidomide in chronic heart failure
Am J Cardiovasc Drugs, 7 (2), 127-34
DOI 10.2165/00129784-200707020-00004, PubMed 17503883
T cells in coronary artery disease: different effects of different T-cell subsets
J Am Coll Cardiol, 50 (15), 1459-61
DOI 10.1016/j.jacc.2007.06.041, PubMed 17919565
Chemokines in cardiovascular risk prediction
Thromb Haemost, 97 (5), 748-54
DOI 10.1160/TH07-01-0029, PubMed 17479185
Increased expression of fractalkine (CX3CL1) and its receptor, CX3CR1, in Wegener's granulomatosis--possible role in vascular inflammation
Rheumatology (Oxford), 46 (9), 1422-7
DOI 10.1093/rheumatology/kem168, PubMed 17616549
Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: possible role in inflammation and plaque destabilization
Circulation, 115 (8), 972-80
DOI 10.1161/CIRCULATIONAHA.106.665893, PubMed 17283255
Low numbers of regulatory T cells in common variable immunodeficiency: association with chronic inflammation in vivo
Clin Exp Immunol, 147 (3), 521-5
DOI 10.1111/j.1365-2249.2006.03314.x, PubMed 17302902
The role of statins in heart failure
Fundam Clin Pharmacol, 21 Suppl 2, 35-40
DOI 10.1111/j.1472-8206.2007.00538.x, PubMed 18001320
Effect of smoking cessation on markers of inflammation and endothelial cell activation among individuals with high risk for cardiovascular disease
Scand J Clin Lab Invest, 67 (6), 604-11
DOI 10.1080/00365510701283878, PubMed 17852807
Inflammation and coronary angiography in asymptomatic type 2 diabetic subjects
Scand J Clin Lab Invest, 67 (3), 306-16
DOI 10.1080/00365510601045088, PubMed 17454845
Plasma osteoprotegerin levels in the general population: relation to indices of left ventricular structure and function
Hypertension, 49 (6), 1392-8
DOI 10.1161/HYPERTENSIONAHA.107.087742, PubMed 17470718
Raised LIGHT levels in pulmonary arterial hypertension: potential role in thrombus formation
Am J Respir Crit Care Med, 177 (2), 202-7
DOI 10.1164/rccm.200703-506OC, PubMed 17962639
Plasma levels of granzyme B are increased in patients with lipid-rich carotid plaques as determined by echogenicity
Atherosclerosis, 195 (2), e142-6
DOI 10.1016/j.atherosclerosis.2007.05.001, PubMed 17568588
Greater symptom duration predicts response to immunomodulatory therapy in dilated cardiomyopathy
Int J Cardiol, 128 (1), 38-41
DOI 10.1016/j.ijcard.2007.05.016, PubMed 17707091
Treatment-related differences in cardiovascular risk factors in long-term survivors of testicular cancer
J Cancer Surviv, 1 (1), 8-16
DOI 10.1007/s11764-007-0012-3, PubMed 18648940
Role of inflammation in the progression of heart failure
Curr Cardiol Rep, 9 (3), 236-41
DOI 10.1007/BF02938356, PubMed 17470337
Publications 2006
Relation of osteoprotegerin to coronary calcium and aortic plaque (from the Dallas Heart Study)
Am J Cardiol, 99 (4), 513-8
DOI 10.1016/j.amjcard.2006.08.064, PubMed 17293196
The role of intravenous immunoglobulin in the treatment of chronic heart failure
Int J Cardiol, 112 (1), 40-5
DOI 10.1016/j.ijcard.2006.05.015, PubMed 16893578
Anti-inflammatory trials in chronic heart failure
Heart Fail Monit, 5 (1), 2-9
PubMed 16547529
Systemic markers of inflammation--are they useful predictive tools in coronary artery disease?
Scand Cardiovasc J, 40 (5), 262-6
DOI 10.1080/14017430600970645, PubMed 17012135
Increased levels of soluble CD40L in African tick bite fever: possible involvement of TLRs in the pathogenic interaction between Rickettsia africae, endothelial cells, and platelets
J Immunol, 177 (4), 2699-706
DOI 10.4049/jimmunol.177.4.2699, PubMed 16888032
Enhanced expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental atherosclerosis: possible pathogenic role in plaque destabilization
Arterioscler Thromb Vasc Biol, 27 (3), 614-20
DOI 10.1161/01.ATV.0000255581.38523.7c, PubMed 17170367
Tetradecylselenoacetic acid, a PPAR ligand with antioxidant, antiinflammatory, and hypolipidemic properties
Arterioscler Thromb Vasc Biol, 27 (3), 628-34
DOI 10.1161/01.ATV.0000255950.70774.d5, PubMed 17185614
Activin A inhibits organization of sarcomeric proteins in cardiomyocytes induced by leukemia inhibitory factor
J Mol Cell Cardiol, 41 (4), 689-97
DOI 10.1016/j.yjmcc.2006.07.009, PubMed 16926021
Role of interleukin-10 in atherogenesis and plaque stabilization
Future Cardiol, 2 (1), 75-83
DOI 10.2217/14796678.2.1.75, PubMed 19804134
Inflammatory interactions between nonalcoholic fatty liver disease and the metabolic syndrome
J. Hepatol., 45 (6), 881-882
DOI 10.1016/j.jhep.2006.09.006
Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2
J Hepatol, 44 (6), 1167-74
DOI 10.1016/j.jhep.2006.02.011, PubMed 16618517
Polyclonal expansion of large granular lymphocytes in common variable immunodeficiency - association with neutropenia
Clin Exp Immunol, 144 (3), 418-24
DOI 10.1111/j.1365-2249.2006.03086.x, PubMed 16734610
A protective anti-inflammatory phenotype in high-risk individuals who do not develop coronary artery disease
J Am Coll Cardiol, 47 (5), 1085-6
DOI 10.1016/j.jacc.2005.11.042, PubMed 16516099
Enhanced platelet activation in hyperhomocysteinemic individuals
J Thromb Haemost, 5 (1), 193-5
DOI 10.1111/j.1538-7836.2006.02275.x, PubMed 17059422
Increased levels of C-reactive protein and interleukin-6 in hyperhomocysteinemic subjects
Scand J Clin Lab Invest, 66 (1), 45-54
DOI 10.1080/00335510500429821, PubMed 16464786
Impaired inhibitory effect of interleukin-10 on the balance between matrix metalloproteinase-9 and its inhibitor in mononuclear cells from hyperhomocysteinemic subjects
Stroke, 37 (7), 1731-6
DOI 10.1161/01.STR.0000226465.84561.cb, PubMed 16728689
Undiagnosed dysglycaemia and inflammation in cardiovascular disease
Eur J Clin Invest, 36 (8), 544-51
DOI 10.1111/j.1365-2362.2006.01679.x, PubMed 16893376
Immune modulatory effects of cyclooxygenase type 2 inhibitors in HIV patients on combination antiretroviral treatment
AIDS, 20 (6), 813-20
DOI 10.1097/01.aids.0000218544.54586.f1, PubMed 16549964
Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes
Blood, 108 (3), 928-35
DOI 10.1182/blood-2005-09-010629, PubMed 16861346
Enhanced T-cell expression of RANK ligand in acute coronary syndrome: possible role in plaque destabilization
Arterioscler Thromb Vasc Biol, 26 (4), 857-63
DOI 10.1161/01.ATV.0000204334.48195.6a, PubMed 16424351
Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation
J Am Coll Cardiol, 48 (8), 1591-9
DOI 10.1016/j.jacc.2006.06.060, PubMed 17045893
The tumor necrosis factor superfamily in heart failure
Future Cardiol, 2 (1), 101-11
DOI 10.2217/14796678.2.1.101, PubMed 19804137
Mannose binding lectin and soluble Toll-like receptor 2 in heart failure following acute myocardial infarction
J Card Fail, 12 (8), 659-63
DOI 10.1016/j.cardfail.2006.07.002, PubMed 17045187
Decreased endomyocardial RANKL expression in transplant coronary artery disease
Transplantation, 81 (10), 1467-70
DOI 10.1097/01.tp.0000209413.45179.f6, PubMed 16732187
Increased inflammatory markers in children with familial hypercholesterolaemia
Eur J Clin Invest, 36 (3), 147-52
DOI 10.1111/j.1365-2362.2006.01613.x, PubMed 16506958
Clopidogrel increases expression of chemokines in peripheral blood mononuclear cells in patients with coronary artery disease: results of a double-blind placebo-controlled study
J Thromb Haemost, 4 (10), 2140-7
DOI 10.1111/j.1538-7836.2006.02131.x, PubMed 16856976
Systemic inflammation in heart failure--the whys and wherefores
Heart Fail Rev, 11 (1), 83-92
DOI 10.1007/s10741-006-9196-2, PubMed 16819581
Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats
Eur J Heart Fail, 8 (8), 790-6
DOI 10.1016/j.ejheart.2006.02.007, PubMed 16549389
Publications 2005
Inflammatory and anti-inflammatory cytokines in chronic heart failure: potential therapeutic implications
Ann Med, 37 (2), 74-85
DOI 10.1080/07853890510007232, PubMed 16026115
Impaired base excision repair and accumulation of oxidative base lesions in CD4+ T cells of HIV-infected patients
Blood, 105 (12), 4730-5
DOI 10.1182/blood-2004-11-4272, PubMed 15705786
Potential role for immunomodulatory therapy in atherosclerotic plaque stabilisation
Expert Opin Pharmacother, 6 (13), 2169-80
DOI 10.1517/14656566.6.13.2169, PubMed 16218879
Inflammation in coronary artery disease: potential role for immunomodulatory therapy
Expert Rev Cardiovasc Ther, 3 (6), 1111-24
DOI 10.1586/14779072.3.6.1111, PubMed 16293001
Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, is elevated in coronary artery disease and is reduced during statin therapy
Arterioscler Thromb Vasc Biol, 25 (12), 2567-72
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Early anti-thrombotic and anti-inflammatory actions of statins and fibrates--time for adjuvant therapy in acute coronary syndromes?
Thromb Haemost, 94 (1), 1-3
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Antiinflammatory effects of tetradecylthioacetic acid involve both peroxisome proliferator-activated receptor alpha-dependent and -independent pathways
Arterioscler Thromb Vasc Biol, 25 (7), 1364-9
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Common variable immunodeficiency and the complement system; low mannose-binding lectin levels are associated with bronchiectasis
Clin Exp Immunol, 142 (3), 576-84
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Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischaemia, and rejection after human heart transplantation
Eur Heart J, 26 (16), 1660-5
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Down-regulated expression of PPARalpha target genes, reduced fatty acid oxidation and altered fatty acid composition in the liver of mice transgenic for hTNFalpha
Biochim Biophys Acta, 1734 (3), 235-46
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Review of trials in chronic heart failure showing broad-spectrum anti-inflammatory approaches
Am J Cardiol, 95 (11A), 17C-23C; discussion 38C-40C
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Agents targeting inflammation in heart failure
Expert Opin Investig Drugs, 14 (5), 557-66
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Effect of thalidomide on cardiac remodeling in chronic heart failure: results of a double-blind, placebo-controlled study
Circulation, 112 (22), 3408-14
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Etanercept or intravenous immunoglobulin attenuates expression of genes involved in post-myocardial infarction remodeling
Cardiovasc Res, 67 (1), 106-15
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Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection
Eur J Clin Invest, 35 (12), 765-70
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Inflammation and depression: further studies are needed
J ECT, 21 (1), 52
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Inflammatory response and re-stenosis after percutaneous coronary intervention in heart transplant recipients and patients with native atherosclerosis
J Heart Lung Transplant, 24 (8), 1026-32
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Chemokines in children with heterozygous familiar hypercholesterolemia: selective upregulation of RANTES
Arterioscler Thromb Vasc Biol, 26 (1), 200-5
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Cytokine responses to fungal pathogens in Kupffer Cells are Toll-like receptor 4 independent and mediated by tyrosine kinases
Scand J Immunol, 62 (2), 148-54
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Enhanced plasma levels of LIGHT in unstable angina: possible pathogenic role in foam cell formation and thrombosis
Circulation, 112 (14), 2121-9
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Increased expression of chemokines in patients with Wegener's granulomatosis - modulating effects of methylprednisolone in vitro
Clin Exp Immunol, 140 (2), 376-83
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Soluble CD40 ligand in acute and chronic heart failure
Eur Heart J, 26 (11), 1101-7
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Plasma levels of soluble tumor necrosis factor receptor type I during the acute phase following complicated myocardial infarction predicts survival in high-risk patients
J Am Coll Cardiol, 46 (11), 2018-21
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Dysregulated osteoprotegerin/RANK ligand/RANK axis in clinical and experimental heart failure
Circulation, 111 (19), 2461-8
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Publications 2004
Soluble CD40 ligand and platelets: self-perpetuating pathogenic loop in thrombosis and inflammation?
J Am Coll Cardiol, 43 (12), 2326-8
DOI 10.1016/j.jacc.2004.03.023, PubMed 15193701
Inflammation and chronic heart failure-potential therapeutic role of intravenous immunoglobulin
Autoimmun Rev, 3 (3), 221-7
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Therapeutic potential of anticytokine therapy in congestive heart failure
Am J Cardiovasc Drugs, 4 (3), 169-77
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Expression of matrix metalloproteinases in patients with Wegener's granulomatosis
Ann Rheum Dis, 63 (12), 1659-63
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Soluble CD40 ligand in pulmonary arterial hypertension: possible pathogenic role of the interaction between platelets and endothelial cells
Circulation, 110 (8), 999-1005
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Lipid-lowering and anti-inflammatory effects of tetradecylthioacetic acid in HIV-infected patients on highly active antiretroviral therapy
Eur J Clin Invest, 34 (10), 709-15
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Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms
J Lipid Res, 46 (2), 211-9
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Stimulation of toll-like receptor 2 in mononuclear cells from HIV-infected patients induces chemokine responses: possible pathogenic consequences
Clin Exp Immunol, 138 (1), 116-21
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Soluble toll-like receptor 2 in HIV infection: association with disease progression
AIDS, 18 (18), 2437-9
PubMed 15622324
Increased expression of toll-like receptor 2 on monocytes in HIV infection: possible roles in inflammation and viral replication
Clin Infect Dis, 39 (2), 264-9
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Effects of conventional and aggressive statin treatment on markers of endothelial function and inflammation
Clin Cardiol, 27 (4), 199-203
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Platelet activation in heart transplant recipients
Clin Transplant, 18 (2), 142-7
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Abnormal interleukin-7 function in common variable immunodeficiency
Blood, 105 (7), 2887-90
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Gene expression analysis of peripheral T cells in a subgroup of common variable immunodeficiency shows predominance of CCR7(-) effector-memory T cells
Clin Exp Immunol, 138 (2), 278-89
DOI 10.1111/j.1365-2249.2004.02630.x, PubMed 15498038
Cytokine networks are pre-activated in T cells from HIV-infected patients on HAART and are under the control of cAMP
AIDS, 18 (2), 171-9
DOI 10.1097/00002030-200401230-00005, PubMed 15075533
Treatment with type-2 selective and non-selective cyclooxygenase inhibitors improves T-cell proliferation in HIV-infected patients on highly active antiretroviral therapy
AIDS, 18 (6), 951-2
DOI 10.1097/00002030-200404090-00015, PubMed 15060445
The epidermal growth factor-like growth factor amphiregulin is strongly induced by the adenosine 3',5'-monophosphate pathway in various cell types
Endocrinology, 145 (11), 5177-84
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Effect of exercise training in patients with heart failure: a pilot study on autonomic balance assessed by heart rate variability
Eur J Cardiovasc Prev Rehabil, 11 (2), 162-7
DOI 10.1097/01.hjr.0000124214.21584.bb, PubMed 15187821
Beneficial effect on cardiac function by intravenous immunoglobulin treatment in patients with dilated cardiomyopathy is not due to neutralization of anti-receptor autoantibody
Autoimmunity, 37 (6-7), 489-93
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[Should patients with severe sepsis be treated with activated protein C?]
Tidsskr Nor Laegeforen, 124 (6), 782-4
PubMed 15039808
8-isoprostane increases scavenger receptor A and matrix metalloproteinase activity in THP-1 macrophages, resulting in long-lived foam cells
Eur J Clin Invest, 34 (7), 451-8
DOI 10.1111/j.1365-2362.2004.01376.x, PubMed 15255781
Potential anti-inflammatory role of activin A in acute coronary syndromes
J Am Coll Cardiol, 44 (2), 369-75
DOI 10.1016/j.jacc.2004.03.069, PubMed 15261933
Prognostic value of osteoprotegerin in heart failure after acute myocardial infarction
J Am Coll Cardiol, 44 (10), 1970-6
DOI 10.1016/j.jacc.2004.06.076, PubMed 15542278
Effect of activated platelets on expression of cytokines in peripheral blood mononuclear cells - potential role of prostaglandin E2
Thromb Haemost, 92 (6), 1358-67
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Increased expression of interleukin-1 in coronary artery disease with downregulatory effects of HMG-CoA reductase inhibitors
Circulation, 109 (16), 1966-72
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Peptidoglycan of Staphylococcus aureus causes inflammation and organ injury in the rat
Crit Care Med, 32 (2), 546-52
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Elevated levels of activin A in heart failure: potential role in myocardial remodeling
Circulation, 109 (11), 1379-85
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Publications 2003
Immunomodulating therapy: new treatment modality in congestive heart failure
Congest Heart Fail, 9 (2), 64-9
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Disturbed glutathione metabolism and decreased antioxidant levels in human immunodeficiency virus-infected patients during highly active antiretroviral therapy--potential immunomodulatory effects of antioxidants
J Infect Dis, 188 (2), 232-8
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Immunomodulating effects of 3-thia fatty acids in activated peripheral blood mononuclear cells
Eur J Clin Invest, 33 (5), 426-33
DOI 10.1046/j.1365-2362.2003.01140.x, PubMed 12713457
Interleukin-7-mediated inflammation in unstable angina: possible role of chemokines and platelets
Circulation, 107 (21), 2670-6
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Mannose-binding lectin in HIV infection: relation to disease progression and highly active antiretroviral therapy
J Acquir Immune Defic Syndr, 32 (4), 354-61
DOI 10.1097/00126334-200304010-00002, PubMed 12640191
Raised plasma levels of tumor necrosis factor alpha in patients with depression: normalization during electroconvulsive therapy
J ECT, 19 (4), 183-8
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Impaired secretion of IL-10 by T cells from patients with common variable immunodeficiency--involvement of protein kinase A type I
J Immunol, 170 (11), 5772-7
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CXC-chemokines in coronary artery disease: possible pathogenic role of interactions between oxidized low-density lipoprotein, platelets and peripheral blood mononuclear cells
J Thromb Haemost, 1 (2), 257-62
DOI 10.1046/j.1538-7836.2003.00065.x, PubMed 12871498
Expression of matrix metalloproteinase-9 in mononuclear cells of hyperhomocysteinaemic subjects
Eur J Clin Invest, 33 (7), 555-60
DOI 10.1046/j.1365-2362.2003.01189.x, PubMed 12814391
Folic acid treatment reduces elevated plasma levels of asymmetric dimethylarginine in hyperhomocysteinaemic subjects
Br J Nutr, 89 (3), 359-63
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Patients with familial hypercholesterolaemia show enhanced spontaneous chemokine release from peripheral blood mononuclear cells ex vivo. Dependency of xanthomas/xanthelasms, smoking and gender
Eur Heart J, 24 (19), 1756-62
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Hyperhomocysteinemic subjects have enhanced expression of lectin-like oxidized LDL receptor-1 in mononuclear cells
J Nutr, 133 (11), 3588-91
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Systemic inflammatory responses in African tick-bite fever
J Infect Dis, 187 (8), 1332-6
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Systematic inflammatory responses in African tick-bite fever
In Journal of infectious diseases, University of Chicago Press, Chicago, 187(2003)8, s.1332-6
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Prognostic usefulness of an increase of N-terminal proatrial natriuretic peptide during exercise in patients with chronic heart failure
Am J Cardiol, 92 (1), 91-4
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Circulating antioxidants and lipid peroxidation products in untreated tuberculosis patients in Ethiopia
Am J Clin Nutr, 78 (1), 117-22
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Cytomegalovirus infection induces production of human interleukin-10 in macrophages
Eur J Clin Microbiol Infect Dis, 22 (12), 737-41
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Complement activation and cytokine and chemokines release during mediastinitis
Ann Thorac Surg, 75 (3), 981-5
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Changes in the cytokine network and complement parameters during open heart surgery
Interact Cardiovasc Thorac Surg, 2 (1), 19-24
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8-isoprostane increases expression of interleukin-8 in human macrophages through activation of mitogen-activated protein kinases
Cardiovasc Res, 59 (4), 945-54
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Raised serum levels of soluble CD40 ligand in patients with familial hypercholesterolemia: downregulatory effect of statin therapy
J Am Coll Cardiol, 41 (2), 275-9
DOI 10.1016/s0735-1097(02)02718-3, PubMed 12535822
Raised serum levels of soluble CD40 ligand in patients with familial hypercholesterolemia: downregulatory effect of statin therapy
In Journal of the American College of Cardiology, Elsevier, New York, 41(2003)2, s.275-9
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Raised serum levels of interleukin-18 is associated with disease progression and may contribute to virological treatment failure in HIV-1-infected patients
Clin Exp Immunol, 132 (3), 462-6
DOI 10.1046/j.1365-2249.2003.02179.x, PubMed 12780693
Interleukin-1 receptor antagonist is associated with fat distribution in endogenous Cushing's syndrome: a longitudinal study
J Clin Endocrinol Metab, 88 (4), 1492-6
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Myocardial gene expression of inflammatory cytokines after heart transplantation in relation to the development of transplant coronary artery disease
Am J Cardiol, 92 (6), 715-7
DOI 10.1016/s0002-9149(03)00836-1, PubMed 12972116
Hydroxymethylglutaryl coenzyme a reductase inhibitors down-regulate chemokines and chemokine receptors in patients with coronary artery disease
J Am Coll Cardiol, 41 (9), 1460-7
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