Katja Benedikte Prestø Elgstøen
- Group Leader; PhD
- +47 230 73 079
Education
2006-2010: PhD in Medical Chemistry, University of Oslo, Norway
1995-1997: MSc in Organic Analytical Chemistry, University of Oslo, Norway
Affiliation
- Metabolomics & Metabolic Molecular Biology Group, Department of Medical Biochemistry, Oslo University Hospital - Rikshospitalet, Norway
Research Summary
PLease reffer to the Welcome Page.
Work Experience
- 1997-to date: Oslo University Hospital, Norway
Dr. Elgstøen currently is:
1) Head of the research group "Metabolomics & Metabolic Molecular Biology"
2) Head of development at the “National Laboratory for Advanced Laboratory Diagnosis of Inborn Errors of Metabolism”
Links
NB: Visit our NEWS PAGE for the latest updates and our Gallery for group social events!
Publications 2025
Global Metabolomics Using LC-MS for Clinical Applications
Methods Mol Biol, 2855, 23-39
DOI 10.1007/978-1-0716-4116-3_2, PubMed 39354299
Publications 2024
Can endogenous ethylene glycol production occur in humans? A detailed investigation of adult monozygotic twin sisters
Clin Toxicol (Phila), 1-9 (in press)
DOI 10.1080/15563650.2024.2401076, PubMed 39327950
Method Development for Omics Analyses using Schirmer Strips
Curr Eye Res, 49 (7), 708-716
DOI 10.1080/02713683.2024.2335271, PubMed 38567868
A longitudinal study of the blood and urine metabolome of Vipera berus envenomated dogs
Res Vet Sci, 173, 105287
DOI 10.1016/j.rvsc.2024.105287, PubMed 38718545
A monoallelic UXS1 variant associated with short-limbed short stature
Mol Genet Genomic Med, 12 (6), e2472
DOI 10.1002/mgg3.2472, PubMed 38860481
Publications 2023
Tear and Saliva Metabolomics in Evaporative Dry Eye Disease in Females
Metabolites, 13 (11)
DOI 10.3390/metabo13111125, PubMed 37999221
Ex Vivo Pig Eye Model for Studying Diffusion of Acylcarnitines with Different Physicochemical Properties
J Ocul Pharmacol Ther, 39 (5), 324-331
DOI 10.1089/jop.2022.0159, PubMed 37219540
Increased Sphingomyelin and Free Sialic Acid in Cerebrospinal Fluid of Kearns-Sayre Syndrome: New Findings Using Untargeted Metabolomics
Pediatr Neurol, 143, 68-76
DOI 10.1016/j.pediatrneurol.2023.02.016, PubMed 37018879
Dried blood spot analysis with liquid chromatography and mass spectrometry: Trends in clinical chemistry
J Sep Sci, 46 (15), e2300210
DOI 10.1002/jssc.202300210, PubMed 37269205
A global metabolomics minefield: Confounding effects of preanalytical factors when studying rare disorders
Anal Sci Adv, 4 (7-8), 255-266
DOI 10.1002/ansa.202300010, PubMed 38716308
Publications 2022
Global Metabolomics Discovers Two Novel Biomarkers in Pyridoxine-Dependent Epilepsy Caused by ALDH7A1 Deficiency
Int J Mol Sci, 23 (24)
DOI 10.3390/ijms232416061, PubMed 36555701
Saliva Metabolomics in Dry Mouth Patients with Head and Neck Cancer or Sjögren's Syndrome
Cells, 11 (3)
DOI 10.3390/cells11030323, PubMed 35159133
High Plasma Oxalate Levels Early After Kidney Transplantation Are Associated With Impaired Long-Term Outcomes
Transpl Int, 35, 10240
DOI 10.3389/ti.2022.10240, PubMed 35368646
Metabolomics - a new biochemical golden age for personalised medicine
Tidsskr Nor Laegeforen, 142 (6)
DOI 10.4045/tidsskr.22.0034, PubMed 35383452
Development of quantitative assay for simultaneous measurement of purine metabolites and creatinine in biobanked urine by liquid chromatography-tandem mass spectrometry
Scand J Clin Lab Invest, 82 (1), 37-49
DOI 10.1080/00365513.2021.2015799, PubMed 35048747
Publications 2021
A pioneer study on human 3-nitropropionic acid intoxication: Contributions from metabolomics
J Appl Toxicol, 42 (5), 818-829
DOI 10.1002/jat.4259, PubMed 34725838
Bridging the Polar and Hydrophobic Metabolome in Single-Run Untargeted Liquid Chromatography-Mass Spectrometry Dried Blood Spot Metabolomics for Clinical Purposes
J Proteome Res, 20 (8), 4010-4021
DOI 10.1021/acs.jproteome.1c00326, PubMed 34296888
Effects of nutrition therapy on growth, inflammation and metabolism in immature infants: a study protocol of a double-blind randomized controlled trial (ImNuT)
BMC Pediatr, 21 (1), 19
DOI 10.1186/s12887-020-02425-x, PubMed 33407269
Is oxidative stress an overlooked player in pyridoxine-dependent epilepsy? A focused review
Seizure, 91, 369-373
DOI 10.1016/j.seizure.2021.07.014, PubMed 34298455
Eye Make-up Products and Dry Eye Disease: A Mini Review
Curr Eye Res, 47 (1), 1-11
DOI 10.1080/02713683.2021.1966476, PubMed 34365876
Searching for a UV-filter in the eyes of high-flying birds
Sci Rep, 11 (1), 273
DOI 10.1038/s41598-020-79533-2, PubMed 33431985
Publications 2019
Tear Metabolomics in Dry Eye Disease: A Review
Int J Mol Sci, 20 (15)
DOI 10.3390/ijms20153755, PubMed 31374809
Publications 2016
Metabolic profiling of synovial tissue shows altered glucose and choline metabolism in rheumatoid arthritis samples
Scand J Rheumatol, 46 (2), 160-161
DOI 10.3109/03009742.2016.1164242, PubMed 27098118
Publications 2015
Susceptibility to infections, without concomitant hyper-IgE, reported in 1976, is caused by hypomorphic mutation in the phosphoglucomutase 3 (PGM3) gene
Clin Immunol, 161 (2), 366-72
DOI 10.1016/j.clim.2015.10.002, PubMed 26482871
Continuous age- and sex-adjusted reference intervals of urinary markers for cerebral creatine deficiency syndromes: a novel approach to the definition of reference intervals
Clin Chem, 61 (5), 760-8
DOI 10.1373/clinchem.2014.235564, PubMed 25759465
Publications 2014
Serum albumin and HCO3- regulate separate pools of ATP in human spermatozoa
Hum Reprod, 29 (5), 918-30
DOI 10.1093/humrep/deu028, PubMed 24578478
PGM3 mutations cause a congenital disorder of glycosylation with severe immunodeficiency and skeletal dysplasia
Am J Hum Genet, 95 (1), 96-107
DOI 10.1016/j.ajhg.2014.05.007, PubMed 24931394
Publications 2011
Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa
Hum Reprod, 26 (12), 3249-63
DOI 10.1093/humrep/der317, PubMed 21946930
Publications 2010
Plasma oxalate following kidney transplantation in patients without primary hyperoxaluria
Nephrol Dial Transplant, 25 (7), 2341-5
DOI 10.1093/ndt/gfq065, PubMed 20167571
Liquid chromatography-tandem mass spectrometry determination of oxalate in spot urine
Scand J Clin Lab Invest, 70 (3), 145-50
DOI 10.3109/00365510903578765, PubMed 20402602
Publications 2008
Liquid chromatography-tandem mass spectrometry method for routine measurement of oxalic acid in human plasma
J Chromatogr B Analyt Technol Biomed Life Sci, 873 (1), 31-6
DOI 10.1016/j.jchromb.2008.07.002, PubMed 18755640
Publications 2002
Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the transamidation versus deamidation process
J Biol Chem, 277 (37), 34109-16
DOI 10.1074/jbc.M204521200, PubMed 12093810
Publications 2001
Potential of capillary electrophoresis, tandem mass spectrometry and coupled capillary electrophoresis-tandem mass spectrometry as diagnostic tools
J Chromatogr A, 914 (1-2), 265-75
DOI 10.1016/s0021-9673(00)01117-1, PubMed 11358221