Human induced pluripotent stem cell (hiPSC) technologies in psychiatric molecular genetics
Neuro-immune interactions
Identifying the polygenic basis of the human brain and neurodevelopmental disorders
Understanding the function of ANK3 in psychotic disorders
Identifying mechanisms of rare variants in population level brain imaging genetics for clinical subtyping in neurodevelopmental disorders
Prediction of longitudinal outcome and brain phenotype by polygenic risk scores
Genetics of neuropsychopharmaceutics
Cooperation and biobanking with the national cohorts and further collaboration with other large-scale studies for validation and QC steps
Recent publications
Watson HJ, Thornton LM, Yilmaz Z, Baker JH, Coleman JRI, Adan RAH, Alfredsson L, Andreassen OA, Ask H, Berrettini WH, Boehnke M, Boehm I, Boni C, Buehren K, Bulant J, Burghardt R, Chang X, Cichon S, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, de Zwaan M, Dedoussis Get al.(2021) Common Genetic Variation and Age of Onset of Anorexia Nervosa Biol Psychiatry Glob Open Sci, 2(4), 368-378 DOI 10.1016/j.bpsgos.2021.09.001, PubMed 36324647
Sheikh MA, O'Connell KS, Lekva T, Szabo A, Akkouh IA, Osete JR, Agartz I, Engh JA, Andreou D, Boye B, Bøen E, Elvsåshagen T, Hope S, Frogner Werner MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Melle I, Drange OK, Morken G, Nærland T, Sørensen K, Vaaler AE, Weibell MAet al.(2022) Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation Biol Psychiatry(in press) DOI 10.1016/j.biopsych.2022.06.029, PubMed 36182530
Cheng W, van der Meer D, Parker N, Hindley G, O'Connell KS, Wang Y, Shadrin AA, Alnæs D, Bahrami S, Lin A, Karadag N, Holen B, Fernandez-Cabello S, Fan CC, Dale AM, Djurovic S, Westlye LT, Frei O, Smeland OB, Andreassen OA(2022) Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood Mol Psychiatry(in press) DOI 10.1038/s41380-022-01751-z, PubMed 36100668