Bahrami S, Nordengen K, Rokicki J, Shadrin AA, Rahman Z, Smeland OB, Jaholkowski PP, Parker N, Parekh P, O'Connell KS, Elvsåshagen T, Toft M, Djurovic S, Dale AM, Westlye LT, Kaufmann T, Andreassen OA(2024) The genetic landscape of basal ganglia and implications for common brain disorders Nat Commun, 15(1), 8476 DOI 10.1038/s41467-024-52583-0, PubMed 39353893
García-Marín LM, Campos AI, Diaz-Torres S, Rabinowitz JA, Ceja Z, Mitchell BL, Grasby KL, Thorp JG, Agartz I, Alhusaini S, Ames D, Amouyel P, Andreassen OA, Arfanakis K, Arias-Vasquez A, Armstrong NJ, Athanasiu L, Bastin ME, Beiser AS, Bennett DA, Bis JC, Boks MPM, Boomsma DI, Brodaty H, Brouwer RMet al.(2024) Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries Nat Genet, 56(11), 2333-2344 DOI 10.1038/s41588-024-01951-z, PubMed 39433889
García-Marín LM, Campos AI, Diaz-Torres S, Rabinowitz JA, Ceja Z, Mitchell BL, Grasby KL, Thorp JG, Agartz I, Alhusaini S, Ames D, Amouyel P, Andreassen OA, Arfanakis K, Vasquez AA, Armstrong NJ, Athanasiu L, Bastin ME, Beiser AS, Bennett DA, Bis JC, Boks MP, Boomsma DI, Brodaty H, Brouwer RMet al.(2024) Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries medRxiv DOI 10.1101/2024.08.13.24311922, PubMed 39371125
Hindley G, Drange OK, Lin A, Kutrolli G, Shadrin AA, Parker N, O'Connell KS, Rødevand L, Cheng W, Bahrami S, Karadag N, Holen B, Jaholkowski P, Woldeyohannes MT, Djurovic S, Dale AM, Frei O, Ueland T, Smeland OB, Andreassen OA(2024) Corrigendum to "Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders" [Psychoneuroendocrinology 157 (2023) 106368] Psychoneuroendocrinology, 162, 106980 DOI 10.1016/j.psyneuen.2024.106980, PubMed 38336601
Holmgren A, Akkouh I, O'Connell KS, Osete JR, Bjørnstad PM, Djurovic S, Hughes T(2024) Bipolar patients display stoichiometric imbalance of gene expression in post-mortem brain samples Mol Psychiatry, 29(4), 1128-1138 DOI 10.1038/s41380-023-02398-0, PubMed 38351171
Ivarsdottir EV, Gudmundsson J, Tragante V, Sveinbjornsson G, Kristmundsdottir S, Stacey SN, Halldorsson GH, Magnusson MI, Oddsson A, Walters GB, Sigurdsson A, Saevarsdottir S, Beyter D, Thorleifsson G, Halldorsson BV, Melsted P, Stefansson H, Jonsdottir I, Sørensen E, Pedersen OB, Erikstrup C, Bøgsted M, Pøhl M, Røder A, Stroomberg HVet al.(2024) Gene-based burden tests of rare germline variants identify six cancer susceptibility genes Nat Genet, 56(11), 2422-2433 DOI 10.1038/s41588-024-01966-6, PubMed 39472694
Jaholkowski P, Bahrami S, Fominykh V, Hindley GFL, Tesfaye M, Parekh P, Parker N, Filiz TT, Nordengen K, Hagen E, Koch E, Bakken NR, Frei E, Birkenæs V, Rahman Z, Frei O, Haavik J, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Shadrin AA, Andreassen OA(2024) Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development Neurobiol Dis, 106750(in press) DOI 10.1016/j.nbd.2024.106750, PubMed 39608471
Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB(2024) Dissecting the Shared Genetic Architecture of Common Epilepsies With Cortical Brain Morphology Neurol Genet, 10(3), e200143 DOI 10.1212/NXG.0000000000200143, PubMed 38817246
Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Ueland T, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB(2024) Unraveling the shared genetics of common epilepsies and general cognitive ability medRxiv DOI 10.1101/2024.03.25.24304773, PubMed 38585944
Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Ueland T, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB(2024) Unraveling the shared genetics of common epilepsies and general cognitive ability Seizure, 122, 105-112 DOI 10.1016/j.seizure.2024.09.016, PubMed 39388989
Koch E, Kämpe A, Alver M, Sigurðarson S, Einarsson G, Partanen J, Smith RL, Jaholkowski P, Taipale H, Lähteenvuo M, Steen NE, Smeland OB, Djurovic S, Molden E, FinnGen, Estonian Biobank Research Team, Sigurdsson E, Stefánsson H, Stefánsson K, Palotie A, Milani L, O'Connell KS, Andreassen OA(2024) Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study Neuropsychopharmacology, 49(7), 1113-1119 DOI 10.1038/s41386-023-01792-0, PubMed 38184734
Koch E, Pardiñas AF, O'Connell KS, Selvaggi P, Camacho Collados J, Babic A, Marshall SE, Van der Eycken E, Angulo C, Lu Y, Sullivan PF, Dale AM, Molden E, Posthuma D, White N, Schubert A, Djurovic S, Heimer H, Stefánsson H, Stefánsson K, Werge T, Sønderby I, O'Donovan MC, Walters JTR, Milani Let al.(2024) How Real-World Data Can Facilitate the Development of Precision Medicine Treatment in Psychiatry Biol Psychiatry, 96(7), 543-551 DOI 10.1016/j.biopsych.2024.01.001, PubMed 38185234
Lenk HÇ, Koch E, O'Connell KS, Smith RL, Akkouh IA, Djurovic S, Andreassen OA, Molden E(2024) Genome-wide association analysis of treatment resistant schizophrenia for variant discovery and polygenic assessment Hum Genomics, 18(1), 108 DOI 10.1186/s40246-024-00673-x, PubMed 39334510
Mlakar V, Akkouh I, Halff EF, Srivastava DP, Birkenæs V, Ueland T, Quintana DS, Ormerod MBEG, Steen NE, Djurovic S, Andreassen OA, Aas M(2024) Telomere biology and its maintenance in schizophrenia spectrum disorders: Exploring links to cognition Schizophr Res, 272, 89-95 DOI 10.1016/j.schres.2024.08.011, PubMed 39208769
Mäki-Marttunen T, Blackwell KT, Akkouh I, Shadrin A, Valstad M, Elvsåshagen T, Linne ML, Djurovic S, Einevoll GT, Andreassen OA(2024) Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modeling Proc Natl Acad Sci U S A, 121(34), e2312511121 DOI 10.1073/pnas.2312511121, PubMed 39141354
Shadrin AA, Hindley G, Hagen E, Parker N, Tesfaye M, Jaholkowski P, Rahman Z, Kutrolli G, Fominykh V, Djurovic S, Smeland OB, O'Connell KS, van der Meer D, Frei O, Andreassen OA, Dale AM(2024) Dissecting the genetic overlap between three complex phenotypes with trivariate MiXeR medRxiv DOI 10.1101/2024.02.23.24303236, PubMed 38464132
Stefansson H, Walters GB, Sveinbjornsson G, Tragante V, Einarsson G, Helgason H, Sigurðsson A, Beyter D, Snaebjarnarson AS, Ivarsdottir EV, Thorleifsson G, Halldorsson BV, Norddahl G, Styrkarsdottir U, Sturluson A, Holm H, Helgason A, Moore K, Eggertsson HP, Oddsson AH, Jonsdottir GA, Gunnarsson AF, Bjornsdottir G, Gisladottir RS, Thorgeirsson TEet al.(2024) Homozygosity for R47H in TREM2 and the Risk of Alzheimer's Disease N Engl J Med, 390(23), 2217-2219 DOI 10.1056/NEJMc2314334, PubMed 38899702
Strom NI, Gerring ZF, Galimberti M, Yu D, Halvorsen MW, Abdellaoui A, Rodriguez-Fontenla C, Sealock JM, Bigdeli T, Coleman JR, Mahjani B, Thorp JG, Bey K, Burton CL, Luykx JJ, Zai G, Alemany S, Andre C, Askland KD, Banaj N, Barlassina C, Nissen JB, Bienvenu OJ, Black D, Bloch MHet al.(2024) Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci medRxiv DOI 10.1101/2024.03.13.24304161, PubMed 38712091
Szabo A, Akkouh I, Osete JR, de Assis DR, Kondratskaya E, Hughes T, Ueland T, Andreassen OA, Djurovic S(2024) NLRP3 inflammasome mediates astroglial dysregulation of innate and adaptive immune responses in schizophrenia Brain Behav Immun(in press) DOI 10.1016/j.bbi.2024.11.030, PubMed 39617069
Szabo A, O'Connell KS, Akkouh IA, Ueland T, Sønderby IE, Hope S, Røe AB, Dønnum MS, Sjaastad I, Steen NE, Ueland T, Sæther LS, Osete JR, Andreassen OA, Nærland T, Djurovic S(2024) Elevated levels of peripheral and central nervous system immune markers reflect innate immune dysregulation in autism spectrum disorder Psychiatry Res, 342, 116245(in press) DOI 10.1016/j.psychres.2024.116245, PubMed 39481220
Sæther LS, Szabo A, Akkouh IA, Haatveit B, Mohn C, Vaskinn A, Aukrust P, Ormerod MBEG, Eiel Steen N, Melle I, Djurovic S, Andreassen OA, Ueland T, Ueland T(2024) Cognitive and inflammatory heterogeneity in severe mental illness: Translating findings from blood to brain Brain Behav Immun, 118, 287-299 DOI 10.1016/j.bbi.2024.03.014, PubMed 38461955
Tesfaye M, Jaholkowski P, Shadrin AA, van der Meer D, Hindley GFL, Holen B, Parker N, Parekh P, Birkenæs V, Rahman Z, Bahrami S, Kutrolli G, Frei O, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Andreassen OA(2024) Identification of Novel Genomic Loci for Anxiety and Extensive Genetic Overlap with Psychiatric Disorders medRxiv DOI 10.1101/2023.09.01.23294920, PubMed 37693403
Tesfaye M, Jaholkowski P, Shadrin AA, van der Meer D, Hindley GFL, Holen B, Parker N, Parekh P, Birkenæs V, Rahman Z, Bahrami S, Kutrolli G, Frei O, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Andreassen OA(2024) Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders Psychiatry Clin Neurosci, 78(12), 783-791 DOI 10.1111/pcn.13742, PubMed 39301620
Tesfaye M, Shadrin A, Parker N, Jaholkowski P, Parekh P, Kutrolli G, Birkenæs V, Bakken NR, Ask H, Frei O, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Andreassen OA(2024) Comorbidity alters the genetic relationship between anxiety disorders and major depression medRxiv DOI 10.1101/2024.11.19.24317523, PubMed 39606413
Tissink EP, Shadrin AA, van der Meer D, Parker N, Hindley G, Roelfs D, Frei O, Fan CC, Nagel M, Nærland T, Budisteanu M, Djurovic S, Westlye LT, van den Heuvel MP, Posthuma D, Kaufmann T, Dale AM, Andreassen OA(2024) Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study Nat Commun, 15(1), 2655 DOI 10.1038/s41467-024-46817-4, PubMed 38531894
van der Meer D, Cheng W, Rokicki J, Fernandez-Cabello S, Shadrin A, Smeland OB, Ehrhart F, Gülöksüz S, Pries LK, Lin B, Rutten BPF, van Os J, O'Donovan M, Richards AL, Steen NE, Djurovic S, Westlye LT, Andreassen OA, Kaufmann T, , (2024) Clustering Schizophrenia Genes by Their Temporal Expression Patterns Aids Functional Interpretation Schizophr Bull, 50(2), 327-338 DOI 10.1093/schbul/sbad140, PubMed 37824720
Wortinger LA, Stavrum AK, Shadrin AA, Szabo A, Rukke SH, Nerland S, Smelror RE, Jørgensen KN, Barth C, Andreou D, Weibell MA, Djurovic S, Andreassen OA, Thoresen M, Ursini G, Agartz I, Le Hellard S(2024) Divergent epigenetic responses to perinatal asphyxia in severe mental disorders Transl Psychiatry, 14(1), 16 DOI 10.1038/s41398-023-02709-7, PubMed 38191519
Publications 2023
Akkouh IA, Ueland T, Szabo A, Hughes T, Smeland OB, Andreassen OA, Osete JR, Djurovic S(2023) Longitudinal Transcriptomic Analysis of Human Cortical Spheroids Identifies Axonal Dysregulation in the Prenatal Brain as a Mediator of Genetic Risk for Schizophrenia Biol Psychiatry, 95(7), 687-698 DOI 10.1016/j.biopsych.2023.08.017, PubMed 37661009
Bang L, Bahrami S, Hindley G, Smeland OB, Rødevand L, Jaholkowski PP, Shadrin A, Connell KSO, Frei O, Lin A, Rahman Z, Cheng W, Parker N, Fan CC, Dale AM, Djurovic S, Bulik CM, Andreassen OA(2023) Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia nervosa Transl Psychiatry, 13(1), 291 DOI 10.1038/s41398-023-02585-1, PubMed 37658054
Boen R, Kaufmann T, Frei O, van der Meer D, Djurovic S, Andreassen OA, Selmer KK, Alnæs D, Sønderby IE(2023) No signs of neurodegenerative effects in 15q11.2 BP1-BP2 copy number variant carriers in the UK Biobank Transl Psychiatry, 13(1), 61 DOI 10.1038/s41398-023-02358-w, PubMed 36807331
Cheng W, Parker N, Karadag N, Koch E, Hindley G, Icick R, Shadrin A, O'Connell KS, Bjella T, Bahrami S, Rahman Z, Tesfaye M, Jaholkowski P, Rødevand L, Holen B, Lagerberg TV, Steen NE, Djurovic S, Dale AM, Frei O, Smeland OB, Andreassen OA(2023) The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study Lancet Psychiatry, 10(6), 441-451 DOI 10.1016/S2215-0366(23)00143-8, PubMed 37208114
de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, Sims R, Bellenguez C, Quintela I, González-Perez A, Calero M, Franco-Macías E, Macías J, Blesa R, Cervera-Carles L, Menéndez-González Met al.(2023) Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores Nat Commun, 14(1), 716 DOI 10.1038/s41467-023-36192-x, PubMed 36759603
Docherty AR, Mullins N, Ashley-Koch AE, Qin X, Coleman JRI, Shabalin A, Kang J, Murnyak B, Wendt F, Adams M, Campos AI, DiBlasi E, Fullerton JM, Kranzler HR, Bakian AV, Monson ET, Rentería ME, Walss-Bass C, Andreassen OA, Behera C, Bulik CM, Edenberg HJ, Kessler RC, Mann JJ, Nurnberger JIet al.(2023) GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors Am J Psychiatry, 180(10), 723-738 DOI 10.1176/appi.ajp.21121266, PubMed 37777856
Fominykh V, Shadrin AA, Jaholkowski PP, Bahrami S, Athanasiu L, Wightman DP, Uffelmann E, Posthuma D, Selbæk G, Dale AM, Djurovic S, Frei O, Andreassen OA(2023) Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system Neurobiol Dis, 183, 106174 DOI 10.1016/j.nbd.2023.106174, PubMed 37286172
Hindley G, Drange OK, Lin A, Kutrolli G, Shadrin AA, Parker N, O'Connell KS, Rødevand L, Cheng W, Bahrami S, Karadag N, Holen B, Jaholkowski P, Woldeyohannes MT, Djurovic S, Dale AM, Frei O, Ueland T, Smeland OB, Andreassen OA(2023) Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders Psychoneuroendocrinology, 157, 106368 DOI 10.1016/j.psyneuen.2023.106368, PubMed 37659117
Hindley G, Shadrin AA, van der Meer D, Parker N, Cheng W, O'Connell KS, Bahrami S, Lin A, Karadag N, Holen B, Bjella T, Deary IJ, Davies G, Hill WD, Bressler J, Seshadri S, Fan CC, Ueland T, Djurovic S, Smeland OB, Frei O, Dale AM, Andreassen OA(2023) Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy Nat Hum Behav, 7(9), 1584-1600 DOI 10.1038/s41562-023-01630-9, PubMed 37365406
Hjell G, Rokicki J, Szabo A, Holst R, Tesli N, Bell C, Fischer-Vieler T, Werner MCF, Lunding SH, Ormerod MBEG, Johansen IT, Djurovic S, Ueland T, Andreassen OA, Melle I, Lagerberg TV, Mørch-Johnsen L, Steen NE, Haukvik UK(2023) Impulsivity across severe mental disorders: a cross-sectional study of immune markers and psychopharmacotherapy BMC Psychiatry, 23(1), 659 DOI 10.1186/s12888-023-05154-4, PubMed 37674162
Holen B, Kutrolli G, Shadrin AA, Icick R, Hindley G, Rødevand L, O'Connell KS, Frei O, Parker N, Tesfaye M, Deak JD, Jahołkowski P, Dale AM, Djurovic S, Andreassen OA, Smeland OB(2023) Genome-wide analyses reveal shared genetic architecture and novel risk loci between opioid use disorder and general cognitive ability Drug Alcohol Depend, 256, 111058 DOI 10.1016/j.drugalcdep.2023.111058, PubMed 38244365
Holen B, Shadrin AA, Icick R, Filiz TT, Hindley G, Rødevand L, O'Connell KS, Hagen E, Frei O, Bahrami S, Cheng W, Parker N, Tesfaye M, Jahołkowski P, Karadag N, Dale AM, Djurovic S, Smeland OB, Andreassen OA(2023) Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression Addict Biol, 28(6), e13282 DOI 10.1111/adb.13282, PubMed 37252880
Hope S, Shadrin AA, Lin A, Bahrami S, Rødevand L, Frei O, Hübenette SJ, Cheng W, Hindley G, Nag H, Ulstein L, Efrim-Budisteanu M, O'Connell K, Dale AM, Djurovic S, Nærland T, Andreassen OA(2023) Bidirectional genetic overlap between autism spectrum disorder and cognitive traits Transl Psychiatry, 13(1), 295 DOI 10.1038/s41398-023-02563-7, PubMed 37709755
Icick R, Shadrin A, Holen B, Karadag N, Parker N, O'Connell K, Frei O, Bahrami S, Høegh M, Lagerberg T, Cheng W, Seibert T, Djurovic S, Dale A, Zhou H, Edenberg H, Gelernter J, Smeland O, Hindley G, Andreassen O(2023) Identification of Novel Loci and Cross-Disorder Pleiotropy Through Multi-Ancestry Genome-Wide Analysis of Alcohol Use Disorder in Over One Million Individuals Res Sq DOI 10.21203/rs.3.rs-3755915/v1, PubMed 38196616
Jaholkowski P, Hindley GFL, Shadrin AA, Tesfaye M, Bahrami S, Nerhus M, Rahman Z, O'Connell KS, Holen B, Parker N, Cheng W, Lin A, Rødevand L, Karadag N, Frei O, Djurovic S, Dale AM, Smeland OB, Andreassen OA(2023) Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci Schizophr Bull, 49(6), 1654-1664 DOI 10.1093/schbul/sbad063, PubMed 37163672
Jaholkowski P, Shadrin AA, Jangmo A, Frei E, Tesfaye M, Hindley GFL, Haram M, Rahman Z, Athanasiu L, Bakken NR, Holen B, Fominykh V, Kutrolli G, Parekh P, Parker N, Rødevand L, Birkenæs V, Djurovic S, Frei O, O'Connell KS, Smeland OB, Tesli M, Andreassen OA(2023) Associations Between Symptoms of Premenstrual Disorders and Polygenic Liability for Major Psychiatric Disorders JAMA Psychiatry, 80(7), 738-742 DOI 10.1001/jamapsychiatry.2023.1137, PubMed 37163253
Jensen SB, Sheikh MA, Akkouh IA, Szabo A, O'Connell KS, Lekva T, Engh JA, Agartz I, Elvsåshagen T, Ormerod MBEG, Weibell MA, Johnsen E, Kroken RA, Melle I, Drange OK, Nærland T, Vaaler AE, Westlye LT, Aukrust P, Djurovic S, Eiel Steen N, Andreassen OA, Ueland T(2023) Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness Schizophr Bull, 49(3), 635-645 DOI 10.1093/schbul/sbac191, PubMed 36462169
Karadag N, Shadrin AA, O'Connell KS, Hindley GFL, Rahman Z, Parker N, Bahrami S, Fominykh V, Cheng W, Holen B, Alvestad S, Taubøll E, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB(2023) Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders Brain, 146(8), 3392-3403 DOI 10.1093/brain/awad038, PubMed 36757824
Mäki-Marttunen T, Blackwell KT, Akkouh I, Shadrin A, Valstad M, Elvsåshagen T, Linne ML, Djurovic S, Einevoll GT, Andreassen OA(2023) Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modelling bioRxiv DOI 10.1101/2023.06.14.544920, PubMed 37398070
O'Connell KS, Koch E, Lenk HÇ, Akkouh IA, Hindley G, Jaholkowski P, Smith RL, Holen B, Shadrin AA, Frei O, Smeland OB, Steen NE, Dale AM, Molden E, Djurovic S, Andreassen OA(2023) Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia Psychiatry Res, 325, 115217 DOI 10.1016/j.psychres.2023.115217, PubMed 37146461
Oddsson A, Sulem P, Sveinbjornsson G, Arnadottir GA, Steinthorsdottir V, Halldorsson GH, Atlason BA, Oskarsson GR, Helgason H, Nielsen HS, Westergaard D, Karjalainen JM, Katrinardottir H, Fridriksdottir R, Jensson BO, Tragante V, Ferkingstad E, Jonsson H, Gudjonsson SA, Beyter D, Moore KHS, Thordardottir HB, Kristmundsdottir S, Stefansson OA, Rantapää-Dahlqvist Set al.(2023) Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality Nat Commun, 14(1), 3453 DOI 10.1038/s41467-023-38951-2, PubMed 37301908
Oddsson A, Sulem P, Sveinbjornsson G, Arnadottir GA, Steinthorsdottir V, Halldorsson GH, Atlason BA, Oskarsson GR, Helgason H, Nielsen HS, Westergaard D, Karjalainen JM, Katrinardottir H, Fridriksdottir R, Jensson BO, Tragante V, Ferkingstad E, Jonsson H, Gudjonsson SA, Beyter D, Moore KHS, Thordardottir HB, Kristmundsdottir S, Stefansson OA, Rantapää-Dahlqvist Set al.(2023) Publisher Correction: Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality Nat Commun, 14(1), 3923 DOI 10.1038/s41467-023-39492-4, PubMed 37400429
Osete JR, Akkouh IA, Ievglevskyi O, Vandenberghe M, de Assis DR, Ueland T, Kondratskaya E, Holen B, Szabo A, Hughes T, Smeland OB, Steen VM, Andreassen OA, Djurovic S(2023) Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids Mol Psychiatry, 28(7), 3033-3043 DOI 10.1038/s41380-023-01944-0, PubMed 36653674
Parker N, Cheng W, Hindley GFL, O'Connell KS, Karthikeyan S, Holen B, Shadrin AA, Rahman Z, Karadag N, Bahrami S, Lin A, Steen NE, Ueland T, Aukrust P, Djurovic S, Dale AM, Smeland OB, Frei O, Andreassen OA(2023) Genetic Overlap Between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts Biol Psychiatry, 95(1), 62-71 DOI 10.1016/j.biopsych.2023.06.008, PubMed 37348803
Parker N, Cheng W, Hindley GFL, Parekh P, Shadrin AA, Maximov II, Smeland OB, Djurovic S, Dale AM, Westlye LT, Frei O, Andreassen OA(2023) Psychiatric disorders and brain white matter exhibit genetic overlap implicating developmental and neural cell biology Mol Psychiatry, 28(11), 4924-4932 DOI 10.1038/s41380-023-02264-z, PubMed 37759039
Rødevand L, Rahman Z, Hindley GFL, Smeland OB, Frei O, Tekin TF, Kutrolli G, Bahrami S, Hoseth EZ, Shadrin A, Lin A, Djurovic S, Dale AM, Steen NE, Andreassen OA(2023) Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors Am J Psychiatry, 180(11), 815-826 DOI 10.1176/appi.ajp.20220660, PubMed 37752828
Smeland OB, Kutrolli G, Bahrami S, Fominykh V, Parker N, Hindley GFL, Rødevand L, Jaholkowski P, Tesfaye M, Parekh P, Elvsåshagen T, Grotzinger AD, International Multiple Sclerosis Genetics Consortium (IMSGC), International Headache Genetics Consortium (IHGC), Steen NE, van der Meer D, O'Connell KS, Djurovic S, Dale AM, Shadrin AA, Frei O, Andreassen OA(2023) The shared genetic risk architecture of neurological and psychiatric disorders: a genome-wide analysis medRxiv DOI 10.1101/2023.07.21.23292993, PubMed 37503175
Steen NE, Rahman Z, Szabo A, Hindley GFL, Parker N, Cheng W, Lin A, O'Connell KS, Sheikh MA, Shadrin A, Bahrami S, Karthikeyan S, Hoseth EZ, Dale AM, Aukrust P, Smeland OB, Ueland T, Frei O, Djurovic S, Andreassen OA(2023) Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities Schizophr Bull, 49(5), 1345-1354 DOI 10.1093/schbul/sbad082, PubMed 37319439
Tesfaye M, Jaholkowski P, Hindley GFL, Shadrin AA, Rahman Z, Bahrami S, Lin A, Holen B, Parker N, Cheng W, Rødevand L, Frei O, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Andreassen OA(2023) Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis Genome Med, 15(1), 60 DOI 10.1186/s13073-023-01212-4, PubMed 37528461
Torsvik A, Brattbakk HR, Trentani A, Holdhus R, Stansberg C, Bartz-Johannessen CA, Hughes T, Steen NE, Melle I, Djurovic S, Andreassen OA, Steen VM(2023) Patients with schizophrenia and bipolar disorder display a similar global gene expression signature in whole blood that reflects elevated proportion of immature neutrophil cells with association to lipid changes Transl Psychiatry, 13(1), 147 DOI 10.1038/s41398-023-02442-1, PubMed 37147304
Villar JD, Stavrum AK, Spindola LM, Torsvik A, Bjella T, Steen NE, Djurovic S, Andreassen OA, Steen VM, Le Hellard S(2023) Differences in white blood cell proportions between schizophrenia cases and controls are influenced by medication and variations in time of day Transl Psychiatry, 13(1), 211 DOI 10.1038/s41398-023-02507-1, PubMed 37330513
Wortinger LA, Shadrin AA, Szabo A, Nerland S, Smelror RE, Jørgensen KN, Barth C, Andreou D, Thoresen M, Andreassen OA, Djurovic S, Ursini G, Agartz I(2023) The impact of placental genomic risk for schizophrenia and birth asphyxia on brain development Transl Psychiatry, 13(1), 343 DOI 10.1038/s41398-023-02639-4, PubMed 37938559
Aas M, Andreassen OA, Gjerstad J, Rødevand L, Hjell G, Johansen IT, Lunding SH, Ormerod MBEG, Lagerverg TV, Steen NE, Djurovic S, Akkouh I(2023) Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders Sci Rep, 13(1), 13845 DOI 10.1038/s41598-023-40310-6, PubMed 37620394
Publications 2022
Akkouh IA, Hribkova H, Grabiec M, Budinska E, Szabo A, Kasparek T, Andreassen OA, Sun YM, Djurovic S(2022) Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response Schizophr Bull, 48(1), 190-198 DOI 10.1093/schbul/sbab092, PubMed 34357384
Bahrami S, Hindley G, Winsvold BS, O'Connell KS, Frei O, Shadrin A, Cheng W, Bettella F, Rødevand L, Odegaard KJ, Fan CC, Pirinen MJ, Hautakangas HM, HUNT All-In Headache, Dale AM, Djurovic S, Smeland OB, Andreassen OA(2022) Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools Brain, 145(1), 142-153 DOI 10.1093/brain/awab267, PubMed 34273149
Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland Det al.(2022) New insights into the genetic etiology of Alzheimer's disease and related dementias Nat Genet, 54(4), 412-436 DOI 10.1038/s41588-022-01024-z, PubMed 35379992
Birkenes V, Elvsahagen T, Westlye LT, Hoegh MC, Haram M, Werner MCF, Quintana DS, Lunding SH, Martin-Ruiz C, Agartz I, Djurovic S, Steen NE, Andreassen OA, Aas M(2022) Telomeres are shorter and associated with number of suicide attempts in affective disorders J. Affect. Disord., 297, 1032-1039 DOI 10.1016/j.jad.2021.08.135
Cheng W, van der Meer D, Parker N, Hindley G, O'Connell KS, Wang Y, Shadrin AA, Alnæs D, Bahrami S, Lin A, Karadag N, Holen B, Fernandez-Cabello S, Fan CC, Dale AM, Djurovic S, Westlye LT, Frei O, Smeland OB, Andreassen OA(2022) Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood Mol Psychiatry, 27(12), 5167-5176 DOI 10.1038/s41380-022-01751-z, PubMed 36100668
Elkjaer Greenwood Ormerod MB, Ueland T, Frogner Werner MC, Hjell G, Rødevand L, Sæther LS, Lunding SH, Johansen IT, Ueland T, Lagerberg TV, Melle I, Djurovic S, Andreassen OA, Steen NE(2022) Composite immune marker scores associated with severe mental disorders and illness course Brain Behav Immun Health, 24, 100483 DOI 10.1016/j.bbih.2022.100483, PubMed 35856063
Engh JA, Ueland T, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Hope S, Høegh MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Wedervang-Resell K, Weibell MA, Westlye LT, Djurovic Set al.(2022) Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study Schizophr Bull, 48(1), 37-46 DOI 10.1093/schbul/sbab106, PubMed 34499169
Hindley G, Frei O, Shadrin AA, Cheng W, O'Connell KS, Icick R, Parker N, Bahrami S, Karadag N, Roelfs D, Holen B, Lin A, Fan CC, Djurovic S, Dale AM, Smeland OB, Andreassen OA(2022) Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation Am J Psychiatry, 179(11), 833-843 DOI 10.1176/appi.ajp.21101051, PubMed 36069018
Hindley G, O'Connell KS, Rahman Z, Frei O, Bahrami S, Shadrin A, Høegh MC, Cheng W, Karadag N, Lin A, Rødevand L, Fan CC, Djurovic S, Lagerberg TV, Dale AM, Smeland OB, Andreassen OA(2022) The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis Am J Med Genet B Neuropsychiatr Genet, 189(6), 207-218 DOI 10.1002/ajmg.b.32907, PubMed 35841185
Hjell G, Szabo A, Mørch-Johnsen L, Holst R, Tesli N, Bell C, Fischer-Vieler T, Werner MCF, Lunding SH, Ormerod MBEG, Johansen IT, Dieset I, Djurovic S, Melle I, Ueland T, Andreassen OA, Steen NE, Haukvik UK(2022) Interleukin-18 signaling system links to agitation in severe mental disorders Psychoneuroendocrinology, 140, 105721 DOI 10.1016/j.psyneuen.2022.105721, PubMed 35301151
Holmgren A, Hansson L, Bjerkaas-Kjeldal K, Impellizzeri AAR, Gilfillan GD, Djurovic S, Hughes T(2022) Mapping the expression of an ANK3 isoform associated with bipolar disorder in the human brain Transl Psychiatry, 12(1), 45 DOI 10.1038/s41398-022-01784-6, PubMed 35091539
Icick R, Shadrin A, Holen B, Karadag N, Lin A, Hindley G, O'Connell K, Frei O, Bahrami S, Høegh MC, Cheng W, Fan CC, Djurovic S, Dale AM, Lagerberg TV, Smeland OB, Andreassen OA(2022) Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings Neuropsychopharmacology, 47(11), 1883-1891 DOI 10.1038/s41386-022-01401-6, PubMed 35953530
Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, Zettergren A, Mishra A, Ali M, Andrade V, Bellenguez C, Kleineidam L, Küçükali F, Sung YJ, Tesí N, Vromen EM, Wightman DP, Alcolea D, Alegret M, Alvarez I, Amouyel P, Athanasiu L, Bahrami S, Bailly H, Belbin Oet al.(2022) Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers Acta Neuropathol, 144(5), 821-842 DOI 10.1007/s00401-022-02454-z, PubMed 36066633
Johannessen J, Nærland T, Hope S, Torske T, Kaale A, Wirgenes KV, Malt E, Djurovic S, Rietschel M, Andreassen OA(2022) Correction to: Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health Eur J Hum Genet, 30(10), 1198 DOI 10.1038/s41431-021-01021-6, PubMed 34903869
Motazedi E, Cheng W, Thomassen JQ, Frei O, Rongve A, Athanasiu L, Bahrami S, Shadrin A, Ulstein I, Stordal E, Brækhus A, Saltvedt I, Sando SB, O'Connell KS, Hindley G, van der Meer D, Bergh S, Nordestgaard BG, Tybjærg-Hansen A, Bråthen G, Pihlstrøm L, Djurovic S, Frikke-Schmidt R, Fladby T, Aarsland Det al.(2022) Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer's Disease in Nordic Populations J Alzheimers Dis, 88(4), 1533-1544 DOI 10.3233/JAD-220174, PubMed 35848024
Sheikh MA, O'Connell KS, Lekva T, Szabo A, Akkouh IA, Osete JR, Agartz I, Engh JA, Andreou D, Boye B, Bøen E, Elvsåshagen T, Hope S, Frogner Werner MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Melle I, Drange OK, Morken G, Nærland T, Sørensen K, Vaaler AE, Weibell MAet al.(2022) Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation Biol Psychiatry, 93(2), 187-196 DOI 10.1016/j.biopsych.2022.06.029, PubMed 36182530
Sæther LS, Ueland T, Haatveit B, Maglanoc LA, Szabo A, Djurovic S, Aukrust P, Roelfs D, Mohn C, Ormerod MBEG, Lagerberg TV, Steen NE, Melle I, Andreassen OA, Ueland T(2022) Inflammation and cognition in severe mental illness: patterns of covariation and subgroups Mol Psychiatry, 28(3), 1284-1292 DOI 10.1038/s41380-022-01924-w, PubMed 36577840
Torgersen K, Rahman Z, Bahrami S, Hindley GFL, Parker N, Frei O, Shadrin A, O'Connell KS, Tesli M, Smeland OB, Munkhaugen J, Djurovic S, Dammen T, Andreassen OA(2022) Shared genetic loci between depression and cardiometabolic traits PLoS Genet, 18(5), e1010161 DOI 10.1371/journal.pgen.1010161, PubMed 35560157
Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis Get al.(2022) Mapping genomic loci implicates genes and synaptic biology in schizophrenia Nature, 604(7906), 502-508 DOI 10.1038/s41586-022-04434-5, PubMed 35396580
van der Meer D, Shadrin AA, O'Connell K, Bettella F, Djurovic S, Wolfers T, Alnæs D, Agartz I, Smeland OB, Melle I, Sánchez JM, Linden DEJ, Dale AM, Westlye LT, Andreassen OA, Frei O, Kaufmann T(2022) Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology Biol Psychiatry, 92(4), 291-298 DOI 10.1016/j.biopsych.2021.12.007, PubMed 35164939
Wang S, Rhijn JV, Akkouh I, Kogo N, Maas N, Bleeck A, Ortiz IS, Lewerissa E, Wu KM, Schoenmaker C, Djurovic S, van Bokhoven H, Kleefstra T, Nadif Kasri N, Schubert D(2022) Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway Cell Rep, 39(5), 110790 DOI 10.1016/j.celrep.2022.110790, PubMed 35508131
Werner MCF, Wirgenes KV, Shadrin A, Lunding SH, Rødevand L, Hjell G, Ormerod MBEG, Haram M, Agartz I, Djurovic S, Melle I, Aukrust P, Ueland T, Andreassen OA, Steen NE(2022) Immune marker levels in severe mental disorders: associations with polygenic risk scores of related mental phenotypes and psoriasis Transl Psychiatry, 12(1), 38 DOI 10.1038/s41398-022-01811-6, PubMed 35082268
Werner MCF, Wirgenes KV, Shadrin AA, Lunding SH, Rødevand L, Hjell G, Ormerod MBEG, Haram M, Agartz I, Djurovic S, Melle I, Aukrust P, Ueland T, Andreassen OA, Steen NE(2022) Limited association between infections, autoimmune disease and genetic risk and immune activation in severe mental disorders Prog Neuropsychopharmacol Biol Psychiatry, 116, 110511 DOI 10.1016/j.pnpbp.2022.110511, PubMed 35063598
Wightman DP, Jansen IE, Savage JE, Shadrin AA, Bahrami S, Holland D, Rongve A, Børte S, Winsvold BS, Drange OK, Martinsen AE, Skogholt AH, Willer C, Bråthen G, Bosnes I, Nielsen JB, Fritsche LG, Thomas LF, Pedersen LM, Gabrielsen ME, Johnsen MB, Meisingset TW, Zhou W, Proitsi P, Hodges Aet al.(2022) Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease Nat Genet, 54(7), 1062 DOI 10.1038/s41588-022-01126-8, PubMed 35726068
Wilson MN, Thunemann M, Liu X, Lu Y, Puppo F, Adams JW, Kim JH, Ramezani M, Pizzo DP, Djurovic S, Andreassen OA, Mansour AA, Gage FH, Muotri AR, Devor A, Kuzum D(2022) Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex Nat Commun, 13(1), 7945 DOI 10.1038/s41467-022-35536-3, PubMed 36572698
Publications 2021
Akkouh IA, Hughes T, Steen VM, Glover JC, Andreassen OA, Djurovic S, Szabo A(2021) Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia Brain Behav Immun, 94, 235-244 DOI 10.1016/j.bbi.2021.01.037, PubMed 33571628
Andreou D, Steen NE, Jørgensen KN, Smelror RE, Wedervang-Resell K, Nerland S, Westlye LT, Nærland T, Myhre AM, Joa I, Reitan SMK, Vaaler A, Morken G, Bøen E, Elvsåshagen T, Boye B, Malt UF, Aukrust P, Skrede S, Kroken RA, Johnsen E, Djurovic S, Andreassen OA, Ueland T, Agartz I(2021) Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness Psychol Med, 53(4), 1479-1488 DOI 10.1017/S0033291721003056, PubMed 35387700
Bahrami S, Shadrin A, Frei O, O'Connell KS, Bettella F, Krull F, Fan CC, Røssberg JI, Hindley G, Ueland T, Dale AM, Djurovic S, Steen NE, Smeland OB, Andreassen OA(2021) Genetic loci shared between major depression and intelligence with mixed directions of effect Nat Hum Behav, 5(6), 795-801 DOI 10.1038/s41562-020-01031-2, PubMed 33462475
Beck D, de Lange AG, Pedersen ML, Alnaes D, Maximov II, Voldsbekk I, Richard G, Sanders AM, Ulrichsen KM, Dørum ES, Kolskår KK, Høgestøl EA, Steen NE, Djurovic S, Andreassen OA, Nordvik JE, Kaufmann T, Westlye LT(2021) Cardiometabolic risk factors associated with brain age and accelerate brain ageing Hum Brain Mapp, 43(2), 700-720 DOI 10.1002/hbm.25680, PubMed 34626047
Birkenæs V, Elvsåshagen T, Westlye LT, Høegh MC, Haram M, Werner MCF, Quintana DS, Lunding SH, Martin-Ruiz C, Agartz I, Djurovic S, Steen NE, Andreassen OA, Aas M(2021) Telomeres are shorter and associated with number of suicide attempts in affective disorders J Affect Disord, 295, 1032-1039 DOI 10.1016/j.jad.2021.08.135, PubMed 34706411
Blokland GAM, Grove J, Chen CY, Cotsapas C, Tobet S, Handa R, Schizophrenia Working Group of the Psychiatric Genomics Consortium, St Clair D, Lencz T, Mowry BJ, Periyasamy S, Cairns MJ, Tooney PA, Wu JQ, Kelly B, Kirov G, Sullivan PF, Corvin A, Riley BP, Esko T, Milani L, Jönsson EG, Palotie A, Ehrenreich H, Begemann Met al.(2021) Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders Biol Psychiatry, 91(1), 102-117 DOI 10.1016/j.biopsych.2021.02.972, PubMed 34099189
Cheng W, Frei O, van der Meer D, Wang Y, O'Connell KS, Chu Y, Bahrami S, Shadrin AA, Alnæs D, Hindley GFL, Lin A, Karadag N, Fan CC, Westlye LT, Kaufmann T, Molden E, Dale AM, Djurovic S, Smeland OB, Andreassen OA(2021) Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness JAMA Psychiatry, 78(9), 1020-1030 DOI 10.1001/jamapsychiatry.2021.1435, PubMed 34160554
de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, Sims R, Bellenguez C, Quintela I, González-Perez A, Calero M, Franco-Macías E, Macías J, Blesa R, Cervera-Carles L, Menéndez-González Met al.(2021) Common variants in Alzheimer's disease and risk stratification by polygenic risk scores Nat Commun, 12(1), 3417 DOI 10.1038/s41467-021-22491-8, PubMed 34099642
DeMichele-Sweet MAA, Klei L, Creese B, Harwood JC, Weamer EA, McClain L, Sims R, Hernandez I, Moreno-Grau S, Tárraga L, Boada M, Alarcón-Martín E, Valero S, NIA-LOAD Family Based Study Consortium, Alzheimer’s Disease Genetics Consortium (ADGC), Liu Y, Hooli B, Aarsland D, Selbaek G, Bergh S, Rongve A, Saltvedt I, Skjellegrind HK, Engdahl B, Stordal E, Andreassen OAet al.(2021) Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease Mol Psychiatry, 26(10), 5797-5811 DOI 10.1038/s41380-021-01152-8, PubMed 34112972
Fjukstad KK, Athanasiu L, Bahrami S, O'Connell KS, van der Meer D, Bettella F, Dieset I, Steen NE, Djurovic S, Spigset O, Andreassen OA(2021) Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study Pharmacogenomics J, 21(5), 574-585 DOI 10.1038/s41397-021-00234-8, PubMed 33824429
Hindley G, Bahrami S, Steen NE, O'Connell KS, Frei O, Shadrin A, Bettella F, Rødevand L, Fan CC, Dale AM, Djurovic S, Smeland OB, Andreassen OA(2021) Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking Transl Psychiatry, 11(1), 466 DOI 10.1038/s41398-021-01576-4, PubMed 34497263
Johannessen J, Nærland T, Hope S, Torske T, Kaale A, Wirgenes KV, Malt E, Djurovic S, Rietschel M, Andreassen OA(2021) Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health Eur J Hum Genet, 30(10), 1138-1146 DOI 10.1038/s41431-021-00966-y, PubMed 34776508
Kalman JL, Olde Loohuis LM, Vreeker A, McQuillin A, Stahl EA, Ruderfer D, Grigoroiu-Serbanescu M, Panagiotaropoulou G, Ripke S, Bigdeli TB, Stein F, Meller T, Meinert S, Pelin H, Streit F, Papiol S, Adams MJ, Adolfsson R, Adorjan K, Agartz I, Aminoff SR, Anderson-Schmidt H, Andreassen OA, Ardau R, Aubry JMet al.(2021) Characterisation of age and polarity at onset in bipolar disorder Br J Psychiatry, 219(6), 659-669 DOI 10.1192/bjp.2021.102, PubMed 35048876
Krull F, Akkouh I, Hughes T, Bettella F, Athanasiu L, Smeland OB, O'Connell KS, Brattbakk HR, Steen VM, Steen NE, Djurovic S, Andreassen OA(2021) Dose-dependent transcriptional effects of lithium and adverse effect burden in a psychiatric cohort Prog Neuropsychopharmacol Biol Psychiatry, 112, 110408 DOI 10.1016/j.pnpbp.2021.110408, PubMed 34320404
Lam M, Chen CY, Ge T, Xia Y, Hill DW, Trampush JW, Yu J, Knowles E, Davies G, Stahl EA, Huckins L, Liewald DC, Djurovic S, Melle I, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling Iet al.(2021) Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics Neuropsychopharmacology, 46(10), 1788-1801 DOI 10.1038/s41386-021-01023-4, PubMed 34035472
Mullins N, Forstner AJ, O'Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, Børte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, Kamitaki N, Kim M, Krebs K, Panagiotaropoulou G, Schilder BM, Sloofman LG, Steinberg S, Trubetskoy V, Winsvold BS, Won HHet al.(2021) Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology Nat Genet, 53(6), 817-829 DOI 10.1038/s41588-021-00857-4, PubMed 34002096
Mullins N, Kang J, Campos AI, Coleman JRI, Edwards AC, Galfalvy H, Levey DF, Lori A, Shabalin A, Starnawska A, Su MH, Watson HJ, Adams M, Awasthi S, Gandal M, Hafferty JD, Hishimoto A, Kim M, Okazaki S, Otsuka I, Ripke S, Ware EB, Bergen AW, Berrettini WH, Bohus Met al.(2021) Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors Biol Psychiatry, 91(3), 313-327 DOI 10.1016/j.biopsych.2021.05.029, PubMed 34861974
O'Connell KS, Frei O, Bahrami S, Smeland OB, Bettella F, Cheng W, Chu Y, Hindley G, Lin A, Shadrin A, Barrett EA, Lagerberg TV, Steen NE, Dale AM, Djurovic S, Andreassen OA(2021) Characterizing the Genetic Overlap Between Psychiatric Disorders and Sleep-Related Phenotypes Biol Psychiatry, 90(9), 621-631 DOI 10.1016/j.biopsych.2021.07.007, PubMed 34482950
O'Connell KS, Sønderby IE, Frei O, van der Meer D, Athanasiu L, Smeland OB, Alnæs D, Kaufmann T, Westlye LT, Steen VM, Andreassen OA, Hughes T, Djurovic S(2021) Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank Psychol Med, 52(15), 1-11(in press) DOI 10.1017/S0033291721000179, PubMed 33653435
Osete JR, Akkouh IA, de Assis DR, Szabo A, Frei E, Hughes T, Smeland OB, Steen NE, Andreassen OA, Djurovic S(2021) Lithium increases mitochondrial respiration in iPSC-derived neural precursor cells from lithium responders Mol Psychiatry, 26(11), 6789-6805 DOI 10.1038/s41380-021-01164-4, PubMed 34075196
Polushina T, Banerjee N, Giddaluru S, Bettella F, Espeseth T, Lundervold AJ, Djurovic S, Cichon S, Hoffmann P, Nöthen MM, Steen VM, Andreassen OA, Le Hellard S(2021) Identification of pleiotropy at the gene level between psychiatric disorders and related traits Transl Psychiatry, 11(1), 410 DOI 10.1038/s41398-021-01530-4, PubMed 34326310
Puppo F, Sadegh S, Trujillo CA, Thunemann M, Campbell EP, Vandenberghe M, Shan X, Akkouh IA, Miller EW, Bloodgood BL, Silva GA, Dale AM, Einevoll GT, Djurovic S, Andreassen OA, Muotri AR, Devor A(2021) All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors Front Cell Neurosci, 15, 671549 DOI 10.3389/fncel.2021.671549, PubMed 34122014
Reis de Assis D, Szabo A, Requena Osete J, Puppo F, O'Connell KS, A Akkouh I, Hughes T, Frei E, A Andreassen O, Djurovic S(2021) Using iPSC Models to Understand the Role of Estrogen in Neuron-Glia Interactions in Schizophrenia and Bipolar Disorder Cells, 10(2) DOI 10.3390/cells10020209, PubMed 33494281
Rødevand L, Bahrami S, Frei O, Chu Y, Shadrin A, O'Connell KS, Smeland OB, Elvsåshagen T, Hindley GFL, Djurovic S, Dale AM, Lagerberg TV, Steen NE, Andreassen OA(2021) Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes Transl Psychiatry, 11(1), 407 DOI 10.1038/s41398-021-01527-z, PubMed 34301917
Rødevand L, Bahrami S, Frei O, Lin A, Gani O, Shadrin A, Smeland OB, Connell KSO, Elvsåshagen T, Winterton A, Quintana DS, Hindley GFL, Werner MCF, Djurovic S, Dale AM, Lagerberg TV, Steen NE, Andreassen OA(2021) Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms Transl Psychiatry, 11(1), 3 DOI 10.1038/s41398-020-01142-4, PubMed 33414458
Szabo A, Akkouh IA, Vandenberghe M, Osete JR, Hughes T, Heine V, Smeland OB, Glover JC, Andreassen OA, Djurovic S(2021) A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia Transl Psychiatry, 11(1), 554 DOI 10.1038/s41398-021-01681-4, PubMed 34716291
Szabo A, O'Connell KS, Ueland T, Sheikh MA, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Engh JA, Hope S, Collier Høegh M, Joa I, Johnsen E, Kroken RA, Vik Lagerberg T, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Sørensen Ket al.(2021) Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation Brain Behav Immun, 99, 299-306 DOI 10.1016/j.bbi.2021.10.017, PubMed 34758379
Sønderby IE, Ching CRK, Thomopoulos SI, van der Meer D, Sun D, Villalon-Reina JE, Agartz I, Amunts K, Arango C, Armstrong NJ, Ayesa-Arriola R, Bakker G, Bassett AS, Boomsma DI, Bülow R, Butcher NJ, Calhoun VD, Caspers S, Chow EWC, Cichon S, Ciufolini S, Craig MC, Crespo-Facorro B, Cunningham AC, Dale AMet al.(2021) Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs Hum Brain Mapp, 43(1), 300-328 DOI 10.1002/hbm.25354, PubMed 33615640
Sønderby IE, van der Meer D, Moreau C, Kaufmann T, Walters GB, Ellegaard M, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn NB, Blangero J, Boomsma DI, Brodaty H, Brouwer RM, Bülow R, Bøen R, Cahn W, Calhoun VD, Caspers S, Ching CRK, Cichon S, Ciufolini Set al.(2021) 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans Transl Psychiatry, 11(1), 182 DOI 10.1038/s41398-021-01213-0, PubMed 33753722
Torgersen K, Bahrami S, Frei O, Shadrin A, Connell KSO, Smeland OB, Munkhaugen J, Djurovic S, Dammen T, Andreassen OA(2021) Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors Transl Psychiatry, 11(1), 368 DOI 10.1038/s41398-021-01466-9, PubMed 34226488
Watson HJ, Thornton LM, Yilmaz Z, Baker JH, Coleman JRI, Adan RAH, Alfredsson L, Andreassen OA, Ask H, Berrettini WH, Boehnke M, Boehm I, Boni C, Buehren K, Bulant J, Burghardt R, Chang X, Cichon S, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, de Zwaan M, Dedoussis Get al.(2021) Common Genetic Variation and Age of Onset of Anorexia Nervosa Biol Psychiatry Glob Open Sci, 2(4), 368-378 DOI 10.1016/j.bpsgos.2021.09.001, PubMed 36324647
Wightman DP, Jansen IE, Savage JE, Shadrin AA, Bahrami S, Holland D, Rongve A, Børte S, Winsvold BS, Drange OK, Martinsen AE, Skogholt AH, Willer C, Bråthen G, Bosnes I, Nielsen JB, Fritsche LG, Thomas LF, Pedersen LM, Gabrielsen ME, Johnsen MB, Meisingset TW, Zhou W, Proitsi P, Hodges Aet al.(2021) A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease Nat Genet, 53(9), 1276-1282 DOI 10.1038/s41588-021-00921-z, PubMed 34493870
Wightman DP, Jansen IE, Savage JE, Shadrin AA, Bahrami S, Holland D, Rongve A, Børte S, Winsvold BS, Drange OK, Martinsen AE, Skogholt AH, Willer C, Bråthen G, Bosnes I, Nielsen JB, Fritsche LG, Thomas LF, Pedersen LM, Gabrielsen ME, Johnsen MB, Meisingset TW, Zhou W, Proitsi P, Hodges Aet al.(2021) Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease Nat Genet, 53(12), 1722 DOI 10.1038/s41588-021-00977-x, PubMed 34773122
Wiström ED, O'Connell KS, Karadag N, Bahrami S, Hindley GFL, Lin A, Cheng W, Steen NE, Shadrin A, Frei O, Djurovic S, Dale AM, Andreassen OA, Smeland OB(2021) Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci Addiction, 117(3), 600-610 DOI 10.1111/add.15680, PubMed 34472679
Publications 2020
Akkouh IA, Ueland T, Hansson L, Inderhaug E, Hughes T, Steen NE, Aukrust P, Andreassen OA, Szabo A, Djurovic S(2020) Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells Brain Behav Immun, 87, 634-644 DOI 10.1016/j.bbi.2020.02.008, PubMed 32109548
Bahrami S, Steen NE, Shadrin A, O'Connell K, Frei O, Bettella F, Wirgenes KV, Krull F, Fan CC, Dale AM, Smeland OB, Djurovic S, Andreassen OA(2020) Shared Genetic Loci Between Body Mass Index and Major Psychiatric Disorders: A Genome-wide Association Study JAMA Psychiatry, 77(5), 503-512 DOI 10.1001/jamapsychiatry.2019.4188, PubMed 31913414
Córdova-Palomera A, van der Meer D, Kaufmann T, Bettella F, Wang Y, Alnæs D, Doan NT, Agartz I, Bertolino A, Buitelaar JK, Coynel D, Djurovic S, Dørum ES, Espeseth T, Fazio L, Franke B, Frei O, Håberg A, Le Hellard S, Jönsson EG, Kolskår KK, Lund MJ, Moberget T, Nordvik JE, Nyberg Let al.(2020) Genetic control of variability in subcortical and intracranial volumes Mol Psychiatry, 26(8), 3876-3883 DOI 10.1038/s41380-020-0664-1, PubMed 32047264
Drakulic D, Djurovic S, Syed YA, Trattaro S, Caporale N, Falk A, Ofir R, Heine VM, Chawner SJRA, Rodriguez-Moreno A, van den Bree MBM, Testa G, Petrakis S, Harwood AJ(2020) Copy number variants (CNVs): a powerful tool for iPSC-based modelling of ASD Mol Autism, 11(1), 42 DOI 10.1186/s13229-020-00343-4, PubMed 32487215
Elvsåshagen T, Bahrami S, van der Meer D, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Beyer MK, Blasi G, Borgwardt S, Boye B, Buitelaar J, Bøen E, Celius EG, Cervenka S, Conzelmann A, Coynel D, Di Carlo P, Djurovic S, Eisenacher S, Espeseth T, Fatouros-Bergman H, Flyckt L, Franke Bet al.(2020) The genetic architecture of human brainstem structures and their involvement in common brain disorders Nat Commun, 11(1), 4016 DOI 10.1038/s41467-020-17376-1, PubMed 32782260
Engen MJ, Lyngstad SH, Ueland T, Simonsen CE, Vaskinn A, Smeland O, Bettella F, Lagerberg TV, Djurovic S, Andreassen OA, Melle I(2020) Polygenic scores for schizophrenia and general cognitive ability: associations with six cognitive domains, premorbid intelligence, and cognitive composite score in individuals with a psychotic disorder and in healthy controls Transl Psychiatry, 10(1), 416 DOI 10.1038/s41398-020-01094-9, PubMed 33257657
Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Ching CRK, McMahon MAB, Shatokhina N, Zsembik LCP, Thomopoulos SI, Zhu AH, Strike LT, Agartz I, Alhusaini S, Almeida MAA, Alnæs D, Amlien IK, Andersson M, Ard T, Armstrong NJ, Ashley-Koch A, Atkins JRet al.(2020) The genetic architecture of the human cerebral cortex Science, 367(6484) DOI 10.1126/science.aay6690, PubMed 32193296
Halle KK, Bakke O, Djurovic S, Bye A, Ryeng E, Wisloff U, Andreassen OA, Langaas M(2020) Computationally efficient familywise error rate control in genome-wide association studies using score tests for generalized linear models Scand. J. Stat., 47(4), 1090-1113 DOI 10.1111/sjos.12451
Hughes T, Hansson L, Akkouh I, Hajdarevic R, Bringsli JS, Torsvik A, Inderhaug E, Steen VM, Djurovic S(2020) Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations Sci Rep, 10(1), 9101 DOI 10.1038/s41598-020-65675-w, PubMed 32499510
Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, Almdahl IS, Andersen F, Bergh S, Bettella F, Bjornsson S, Brækhus A, Bråthen G, de Leeuw C, Desikan RS, Djurovic Set al.(2020) Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk Nat Genet, 52(3), 354 DOI 10.1038/s41588-019-0573-x, PubMed 32029921
Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, Buitelaar J, Celius EG, Cervenka S, Conzelmann A, Córdova-Palomera A, Dale AM, de Quervain DJF, Di Carlo P, Djurovic S, Dørum ESet al.(2020) Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain Nat Neurosci, 23(2), 295 DOI 10.1038/s41593-019-0553-6, PubMed 31848485
Reponen EJ, Dieset I, Tesli M, Mørch RH, Aas M, Vedal TSJ, Haug E, Drange OK, Steen NE, Hope S, Szabo A, Gohar SM, Wedervang-Resell K, Djurovic S, Melle I, Aukrust P, Andreassen OA, Ueland T(2020) Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders Front Psychiatry, 11, 672 DOI 10.3389/fpsyt.2020.00672, PubMed 32754070
Richards AL, Pardiñas AF, Frizzati A, Tansey KE, Lynham AJ, Holmans P, Legge SE, Savage JE, Agartz I, Andreassen OA, Blokland GAM, Corvin A, Cosgrove D, Degenhardt F, Djurovic S, Espeseth T, Ferraro L, Gayer-Anderson C, Giegling I, van Haren NE, Hartmann AM, Hubert JJ, Jönsson EG, Konte B, Lennertz Let al.(2020) The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia Schizophr Bull, 46(2), 336-344 DOI 10.1093/schbul/sbz061, PubMed 31206164
Shadrin AA, Frei O, Smeland OB, Bettella F, O'Connell KS, Gani O, Bahrami S, Uggen TKE, Djurovic S, Holland D, Andreassen OA, Dale AM(2020) Phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories revealed by AI-MiXeR Bioinformatics, 36(18), 4749-4756 DOI 10.1093/bioinformatics/btaa568, PubMed 32539089
Smeland OB, Bahrami S, Frei O, Shadrin A, O'Connell K, Savage J, Watanabe K, Krull F, Bettella F, Steen NE, Ueland T, Posthuma D, Djurovic S, Dale AM, Andreassen OA(2020) Correction: Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence Mol Psychiatry, 25(4), 914 DOI 10.1038/s41380-019-0456-7, PubMed 31308466
Smeland OB, Shadrin A, Bahrami S, Broce I, Tesli M, Frei O, Wirgenes KV, O'Connell KS, Krull F, Bettella F, Steen NE, Sugrue L, Wang Y, Svenningsson P, Sharma M, Pihlstrøm L, Toft M, O'Donovan M, Djurovic S, Desikan R, Dale AM, Andreassen OA(2020) Genome-wide Association Analysis of Parkinson's Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci Biol Psychiatry, 89(3), 227-235 DOI 10.1016/j.biopsych.2020.01.026, PubMed 32201043
Smith RL, O'Connell K, Athanasiu L, Djurovic S, Kringen MK, Andreassen OA, Molden E(2020) Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits Transl Psychiatry, 10(1), 198 DOI 10.1038/s41398-020-00888-1, PubMed 32555152
Smith RL, O'Connell K, Athanasiu L, Djurovic S, Kringen MK, Andreassen OA, Molden E(2020) Correction: Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits Transl Psychiatry, 10(1), 366 DOI 10.1038/s41398-020-01061-4, PubMed 33139722
Szabo A, Akkouh IA, Ueland T, Lagerberg TV, Dieset I, Bjella T, Aukrust P, Le Hellard S, Stavrum AK, Melle I, Andreassen OA, Djurovic S(2020) Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder Front Psychiatry, 11, 642 DOI 10.3389/fpsyt.2020.00642, PubMed 32714224
Sønderby IE, Gústafsson Ó, Doan NT, Hibar DP, Martin-Brevet S, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn N, Blangero J, Boomsma DI, Bralten J, Brattbak HR, Brodaty H, Brouwer RM, Bülow R, Calhoun V, Caspers S, Cavalleri G, Chen CH, Cichon S, Ciufolini Set al.(2020) Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia Mol Psychiatry, 25(3), 692-695 DOI 10.1038/s41380-019-0358-8, PubMed 30705424
Werner MCF, Wirgenes KV, Haram M, Bettella F, Lunding SH, Rødevand L, Hjell G, Agartz I, Djurovic S, Melle I, Andreassen OA, Steen NE(2020) Indicated association between polygenic risk score and treatment-resistance in a naturalistic sample of patients with schizophrenia spectrum disorders Schizophr Res, 218, 55-62 DOI 10.1016/j.schres.2020.03.006, PubMed 32171635
Writing Committee for the ENIGMA-CNV Working Group, van der Meer D, Sønderby IE, Kaufmann T, Walters GB, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn NB, Blangero J, Boomsma DI, Brodaty H, Brouwer RM, Bülow R, Cahn W, Calhoun VD, Caspers S, Cavalleri GL, Ching CRK, Cichon S, Ciufolini S, Corvin Aet al.(2020) Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition JAMA Psychiatry, 77(4), 420-430 DOI 10.1001/jamapsychiatry.2019.3779, PubMed 31665216
Publications 2019
Akkouh IA, Skrede S, Holmgren A, Ersland KM, Hansson L, Bahrami S, Andreassen OA, Steen VM, Djurovic S, Hughes T(2019) Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study Neuropsychopharmacology, 45(6), 947-955 DOI 10.1038/s41386-019-0556-8, PubMed 31652432
Alnæs D, Kaufmann T, van der Meer D, Córdova-Palomera A, Rokicki J, Moberget T, Bettella F, Agartz I, Barch DM, Bertolino A, Brandt CL, Cervenka S, Djurovic S, Doan NT, Eisenacher S, Fatouros-Bergman H, Flyckt L, Di Giorgio A, Haatveit B, Jönsson EG, Kirsch P, Lund MJ, Meyer-Lindenberg A, Pergola G, Schwarz Eet al.(2019) Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk JAMA Psychiatry, 76(7), 739-748 DOI 10.1001/jamapsychiatry.2019.0257, PubMed 30969333
Creese B, Vassos E, Bergh S, Athanasiu L, Johar I, Rongve A, Medbøen IT, Vasconcelos Da Silva M, Aakhus E, Andersen F, Bettella F, Braekhus A, Djurovic S, Paroni G, Proitsi P, Saltvedt I, Seripa D, Stordal E, Fladby T, Aarsland D, Andreassen OA, Ballard C, Selbaek G, AddNeuroMed consortium and the Alzheimer’s Disease Neuroimaging Initiative(2019) Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease Transl Psychiatry, 9(1), 273 DOI 10.1038/s41398-019-0592-5, PubMed 31641104
Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward Cet al.(2019) Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function Nat Commun, 10(1), 2068 DOI 10.1038/s41467-019-10160-w, PubMed 31043617
Drange OK, Smeland OB, Shadrin AA, Finseth PI, Witoelar A, Frei O, Psychiatric Genomics Consortium Bipolar Disorder Working Group, Wang Y, Hassani S, Djurovic S, Dale AM, Andreassen OA(2019) Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes Front Neurosci, 13, 220 DOI 10.3389/fnins.2019.00220, PubMed 30930738
Frei O, Holland D, Smeland OB, Shadrin AA, Fan CC, Maeland S, O'Connell KS, Wang Y, Djurovic S, Thompson WK, Andreassen OA, Dale AM(2019) Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation Nat Commun, 10(1), 2417 DOI 10.1038/s41467-019-10310-0, PubMed 31160569
Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic Set al.(2019) Identification of common genetic risk variants for autism spectrum disorder Nat Genet, 51(3), 431-444 DOI 10.1038/s41588-019-0344-8, PubMed 30804558
Gudmundsson OO, Walters GB, Ingason A, Johansson S, Zayats T, Athanasiu L, Sonderby IE, Gustafsson O, Nawaz MS, Jonsson GF, Jonsson L, Knappskog PM, Ingvarsdottir E, Davidsdottir K, Djurovic S, Knudsen GPS, Askeland RB, Haraldsdottir GS, Baldursson G, Magnusson P, Sigurdsson E, Gudbjartsson DF, Stefansson H, Andreassen OA, Haavik Jet al.(2019) Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder Transl Psychiatry, 9(1), 258 DOI 10.1038/s41398-019-0599-y, PubMed 31624239
Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, Almdahl IS, Andersen F, Bergh S, Bettella F, Bjornsson S, Brækhus A, Bråthen G, de Leeuw C, Desikan RS, Djurovic Set al.(2019) Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk Nat Genet, 51(3), 404-413 DOI 10.1038/s41588-018-0311-9, PubMed 30617256
Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, Buitelaar J, Celius EG, Cervenka S, Conzelmann A, Córdova-Palomera A, Dale AM, de Quervain DJF, Di Carlo P, Djurovic S, Dørum ESet al.(2019) Common brain disorders are associated with heritable patterns of apparent aging of the brain Nat Neurosci, 22(10), 1617-1623 DOI 10.1038/s41593-019-0471-7, PubMed 31551603
Lam M, Hill WD, Trampush JW, Yu J, Knowles E, Davies G, Stahl E, Huckins L, Liewald DC, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Hartmann AMet al.(2019) Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways Am J Hum Genet, 105(2), 334-350 DOI 10.1016/j.ajhg.2019.06.012, PubMed 31374203
Mullins N, Bigdeli TB, Børglum AD, Coleman JRI, Demontis D, Mehta D, Power RA, Ripke S, Stahl EA, Starnawska A, Anjorin A, M.R.C.Psych, Corvin A, Sanders AR, Forstner AJ, Reif A, Koller AC, Świątkowska B, Baune BT, Müller-Myhsok B, Penninx BWJH, Pato C, Zai C, Rujescu D, Hougaard DMet al.(2019) GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores Am J Psychiatry, 176(8), 651-660 DOI 10.1176/appi.ajp.2019.18080957, PubMed 31164008
Mäki-Marttunen T, Kaufmann T, Elvsåshagen T, Devor A, Djurovic S, Westlye LT, Linne ML, Rietschel M, Schubert D, Borgwardt S, Efrim-Budisteanu M, Bettella F, Halnes G, Hagen E, Næss S, Ness TV, Moberget T, Metzner C, Edwards AG, Fyhn M, Dale AM, Einevoll GT, Andreassen OA(2019) Biophysical Psychiatry-How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders Front Psychiatry, 10, 534 DOI 10.3389/fpsyt.2019.00534, PubMed 31440172
Mäki-Marttunen T, Krull F, Bettella F, Hagen E, Næss S, Ness TV, Moberget T, Elvsåshagen T, Metzner C, Devor A, Edwards AG, Fyhn M, Djurovic S, Dale AM, Andreassen OA, Einevoll GT(2019) Alterations in Schizophrenia-Associated Genes Can Lead to Increased Power in Delta Oscillations Cereb Cortex, 29(2), 875-891 DOI 10.1093/cercor/bhy291, PubMed 30475994
Mørch RH, Dieset I, Færden A, Reponen EJ, Hope S, Hoseth EZ, Gardsjord ES, Aas M, Iversen T, Joa I, Morken G, Agartz I, Melle I, Aukrust P, Djurovic S, Ueland T, Andreassen OA(2019) Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors Psychol Med, 49(10), 1749-1757 DOI 10.1017/S0033291718004142, PubMed 30688187
Mørch RH, Dieset I, Færden A, Reponen EJ, Hope S, Hoseth EZ, Gardsjord ES, Aas M, Iversen T, Joa I, Morken G, Agartz I, Melle I, Aukrust P, Djurovic S, Ueland T, Andreassen OA(2019) Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors - ERRATUM Psychol Med, 49(10), 1758 DOI 10.1017/S0033291719000291, PubMed 30803457
O'Connell KS, Shadrin A, Bahrami S, Smeland OB, Bettella F, Frei O, Krull F, Askeland RB, Walters GB, Davíðsdóttir K, Haraldsdóttir GS, Guðmundsson ÓÓ, Stefánsson H, Fan CC, Steen NE, Reichborn-Kjennerud T, Dale AM, Stefánsson K, Djurovic S, Andreassen OA(2019) Identification of genetic overlap and novel risk loci for attention-deficit/hyperactivity disorder and bipolar disorder Mol Psychiatry, 26(8), 4055-4065 DOI 10.1038/s41380-019-0613-z, PubMed 31792363
O'Connell KS, Shadrin A, Smeland OB, Bahrami S, Frei O, Bettella F, Krull F, Fan CC, Askeland RB, Knudsen GPS, Halmøy A, Steen NE, Ueland T, Walters GB, Davíðsdóttir K, Haraldsdóttir GS, Guðmundsson ÓÓ, Stefánsson H, Reichborn-Kjennerud T, Haavik J, Dale AM, Stefánsson K, Djurovic S, Andreassen OA(2019) Identification of Genetic Loci Shared Between Attention-Deficit/Hyperactivity Disorder, Intelligence, and Educational Attainment Biol Psychiatry, 87(12), 1052-1062 DOI 10.1016/j.biopsych.2019.11.015, PubMed 32061372
Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, Carrera N, Legge SE, Bishop S, Cameron D, Hamshere ML, Han J, Hubbard L, Lynham A, Mantripragada K, Rees E, MacCabe JH, McCarroll SA, Baune BT, Breen G, Byrne EM, Dannlowski U, Eley TC, Hayward C, Martin NG, McIntosh AMet al.(2019) Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection Nat Genet, 51(7), 1193 DOI 10.1038/s41588-019-0450-7, PubMed 31160808
Rongve A, Witoelar A, Ruiz A, Athanasiu L, Abdelnour C, Clarimon J, Heilmann-Heimbach S, Hernández I, Moreno-Grau S, de Rojas I, Morenas-Rodríguez E, Fladby T, Sando SB, Bråthen G, Blanc F, Bousiges O, Lemstra AW, van Steenoven I, Londos E, Almdahl IS, Pålhaugen L, Eriksen JA, Djurovic S, Stordal E, Saltvedt Iet al.(2019) GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study Sci Rep, 9(1), 7013 DOI 10.1038/s41598-019-43458-2, PubMed 31065058
Rongve A, Witoelar A, Ruiz A, Athanasiu L, Abdelnour C, Clarimon J, Heilmann-Heimbach S, Hernández I, Moreno-Grau S, de Rojas I, Morenas-Rodríguez E, Fladby T, Sando SB, Bråthen G, Blanc F, Bousiges O, Lemstra AW, van Steenoven I, Londos E, Almdahl IS, Pålhaugen L, Eriksen JA, Djurovic S, Stordal E, Saltvedt Iet al.(2019) Author Correction: GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study Sci Rep, 9(1), 15168 DOI 10.1038/s41598-019-51827-0, PubMed 31619746
Sanyal N, Lo MT, Kauppi K, Djurovic S, Andreassen OA, Johnson VE, Chen CH(2019) GWASinlps: non-local prior based iterative SNP selection tool for genome-wide association studies Bioinformatics, 35(1), 1-11 DOI 10.1093/bioinformatics/bty472, PubMed 29931045
Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, Teumer A, van der Lee SJ, Yang J, Yanek LR, Lee TV, Li S, Hu Y, Koh JY, Eicher JD, Desrivières Set al.(2019) Genetic architecture of subcortical brain structures in 38,851 individuals Nat Genet, 51(11), 1624-1636 DOI 10.1038/s41588-019-0511-y, PubMed 31636452
Smeland OB, Bahrami S, Frei O, Shadrin A, O'Connell K, Savage J, Watanabe K, Krull F, Bettella F, Steen NE, Ueland T, Posthuma D, Djurovic S, Dale AM, Andreassen OA(2019) Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence Mol Psychiatry, 25(4), 844-853 DOI 10.1038/s41380-018-0332-x, PubMed 30610197
Smeland OB, Frei O, Shadrin A, O'Connell K, Fan CC, Bahrami S, Holland D, Djurovic S, Thompson WK, Dale AM, Andreassen OA(2019) Discovery of shared genomic loci using the conditional false discovery rate approach Hum Genet, 139(1), 85-94 DOI 10.1007/s00439-019-02060-2, PubMed 31520123
Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin Aet al.(2019) Genome-wide association study identifies 30 loci associated with bipolar disorder Nat Genet, 51(5), 793-803 DOI 10.1038/s41588-019-0397-8, PubMed 31043756
Steen NE, Dieset I, Hope S, Vedal TSJ, Smeland OB, Matson W, Kaddurah-Daouk R, Agartz I, Melle I, Djurovic S, Jönsson EG, Bogdanov M, Andreassen OA(2019) Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders Psychol Med, 50(4), 595-606 DOI 10.1017/S0033291719000400, PubMed 30867076
Aas M, Djurovic S, Ueland T, Mørch RH, Fjæra Laskemoen J, Reponen EJ, Cattaneo A, Eiel Steen N, Agartz I, Melle I, Andreassen OA(2019) The relationship between physical activity, clinical and cognitive characteristics and BDNF mRNA levels in patients with severe mental disorders World J Biol Psychiatry, 20(7), 567-576 DOI 10.1080/15622975.2018.1557345, PubMed 30560709
Aas M, Elvsåshagen T, Westlye LT, Kaufmann T, Athanasiu L, Djurovic S, Melle I, van der Meer D, Martin-Ruiz C, Steen NE, Agartz I, Andreassen OA(2019) Telomere length is associated with childhood trauma in patients with severe mental disorders Transl Psychiatry, 9(1), 97 DOI 10.1038/s41398-019-0432-7, PubMed 30898995
Publications 2018
Akkouh IA, Ueland T, Andreassen OA, Brattbakk HR, Steen VM, Hughes T, Djurovic S(2018) Expression of TCN1 in Blood is Negatively Associated with Verbal Declarative Memory Performance Sci Rep, 8(1), 12654 DOI 10.1038/s41598-018-30898-5, PubMed 30139959
Berg AO, Jørgensen KN, Nerhus M, Athanasiu L, Popejoy AB, Bettella F, Norbom LCB, Gurholt TP, Dahl SR, Andreassen OA, Djurovic S, Agartz I, Melle I(2018) Vitamin D levels, brain volume, and genetic architecture in patients with psychosis PLoS One, 13(8), e0200250 DOI 10.1371/journal.pone.0200250, PubMed 30142216
Bettella F, Brown AA, Smeland OB, Wang Y, Witoelar A, Buil Demur AA, Thompson WK, Zuber V, Dale AM, Djurovic S, Andreassen OA(2018) Cross-tissue eQTL enrichment of associations in schizophrenia PLoS One, 13(9), e0202812 DOI 10.1371/journal.pone.0202812, PubMed 30188921
Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward Cet al.(2018) Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function Nat Commun, 9(1), 2098 DOI 10.1038/s41467-018-04362-x, PubMed 29844566
Dieset I, Mørch RH, Hope S, Hoseth EZ, Reponen EJ, Gran JM, Aas M, Michelsen AE, Reichborn-Kjennerud T, Nesvåg R, Agartz I, Melle I, Aukrust P, Djurovic S, Ueland T, Andreassen OA(2018) An association between YKL-40 and type 2 diabetes in psychotic disorders Acta Psychiatr Scand, 139(1), 37-45 DOI 10.1111/acps.12971, PubMed 30328100
Dusanov S, Ruzzin J, Kiviranta H, Klemsdal TO, Retterstøl L, Rantakokko P, Airaksinen R, Djurovic S, Tonstad S(2018) Associations between persistent organic pollutants and metabolic syndrome in morbidly obese individuals Nutr Metab Cardiovasc Dis, 28(7), 735-742 DOI 10.1016/j.numecd.2018.03.004, PubMed 29699815
Hoseth EZ, Krull F, Dieset I, Mørch RH, Hope S, Gardsjord ES, Steen NE, Melle I, Brattbakk HR, Steen VM, Aukrust P, Djurovic S, Andreassen OA, Ueland T(2018) Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder Transl Psychiatry, 8(1), 55 DOI 10.1038/s41398-018-0102-1, PubMed 29507296
Hoseth EZ, Krull F, Dieset I, Mørch RH, Hope S, Gardsjord ES, Steen NE, Melle I, Brattbakk HR, Steen VM, Aukrust P, Djurovic S, Andreassen OA, Ueland T(2018) Attenuated Notch signaling in schizophrenia and bipolar disorder Sci Rep, 8(1), 5349 DOI 10.1038/s41598-018-23703-w, PubMed 29593239
Hughes T, Sønderby IE, Polushina T, Hansson L, Holmgren A, Athanasiu L, Melbø-Jørgensen C, Hassani S, Hoeffding LK, Herms S, Bergen SE, Karlsson R, Song J, Rietschel M, Nöthen MM, Forstner AJ, Hoffmann P, Hultman CM, Landén M, Cichon S, Werge T, Andreassen OA, Le Hellard S, Djurovic S(2018) Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder Transl Psychiatry, 8(1), 210 DOI 10.1038/s41398-018-0175-x, PubMed 30297702
Kaufmann T, Alnæs D, Brandt CL, Bettella F, Djurovic S, Andreassen OA, Westlye LT(2018) Stability of the Brain Functional Connectome Fingerprint in Individuals With Schizophrenia JAMA Psychiatry, 75(7), 749-751 DOI 10.1001/jamapsychiatry.2018.0844, PubMed 29799905
Kulkarni RU, Vandenberghe M, Thunemann M, James F, Andreassen OA, Djurovic S, Devor A, Miller EW(2018) In Vivo Two-Photon Voltage Imaging with Sulfonated Rhodamine Dyes ACS Cent Sci, 4(10), 1371-1378 DOI 10.1021/acscentsci.8b00422, PubMed 30410975
Lam M, Trampush JW, Yu J, Knowles E, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek Oet al.(2018) Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018) Twin Res Hum Genet, 21(5), 394-397 DOI 10.1017/thg.2018.46, PubMed 30001766
Li W, Fan CC, Mäki-Marttunen T, Thompson WK, Schork AJ, Bettella F, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Djurovic S, Dale AM, Andreassen OA, Wang Y(2018) A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia Am J Med Genet B Neuropsychiatr Genet, 177(4), 454-467 DOI 10.1002/ajmg.b.32634, PubMed 29704319
McCarthy MJ, Wei H, Nievergelt CM, Stautland A, Maihofer AX, Welsh DK, Shilling P, Alda M, Alliey-Rodriguez N, Anand A, Andreasson OA, Balaraman Y, Berrettini WH, Bertram H, Brennand KJ, Calabrese JR, Calkin CV, Claasen A, Conroy C, Coryell WH, Craig DW, D'Arcangelo N, Demodena A, Djurovic S, Feeder Set al.(2018) Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder Neuropsychopharmacology, 44(3), 620-628 DOI 10.1038/s41386-018-0273-8, PubMed 30487653
Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, Carrera N, Legge SE, Bishop S, Cameron D, Hamshere ML, Han J, Hubbard L, Lynham A, Mantripragada K, Rees E, MacCabe JH, McCarroll SA, Baune BT, Breen G, Byrne EM, Dannlowski U, Eley TC, Hayward C, Martin NG, McIntosh AMet al.(2018) Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection Nat Genet, 50(3), 381-389 DOI 10.1038/s41588-018-0059-2, PubMed 29483656
Savage JE, Jansen PR, Stringer S, Watanabe K, Bryois J, de Leeuw CA, Nagel M, Awasthi S, Barr PB, Coleman JRI, Grasby KL, Hammerschlag AR, Kaminski JA, Karlsson R, Krapohl E, Lam M, Nygaard M, Reynolds CA, Trampush JW, Young H, Zabaneh D, Hägg S, Hansell NK, Karlsson IK, Linnarsson Set al.(2018) Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence Nat Genet, 50(7), 912-919 DOI 10.1038/s41588-018-0152-6, PubMed 29942086
Smeland OB, Wang Y, Frei O, Li W, Hibar DP, Franke B, Bettella F, Witoelar A, Djurovic S, Chen CH, Thompson PM, Dale AM, Andreassen OA(2018) Genetic Overlap Between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms Schizophr Bull, 44(4), 854-864 DOI 10.1093/schbul/sbx148, PubMed 29136250
Srinivasan S, Bettella F, Frei O, Hill WD, Wang Y, Witoelar A, Schork AJ, Thompson WK, Davies G, Desikan RS, Deary IJ, Melle I, Ueland T, Dale AM, Djurovic S, Smeland OB, Andreassen OA(2018) Enrichment of genetic markers of recent human evolution in educational and cognitive traits Sci Rep, 8(1), 12585 DOI 10.1038/s41598-018-30387-9, PubMed 30135563
Stokowy T, Polushina T, Sønderby IE, Karlsson R, Giddaluru S, Le Hellard S, Bergen SE, Sullivan PF, Andreassen OA, Djurovic S, Hultman CM, Steen VM(2018) Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes Sci Rep, 8(1), 6915 DOI 10.1038/s41598-018-25280-4, PubMed 29720671
Szabo A, Gogolak P, Koncz G, Foldvari Z, Pazmandi K, Miltner N, Poliska S, Bacsi A, Djurovic S, Rajnavolgyi E(2018) Immunomodulatory capacity of the serotonin receptor 5-HT2B in a subset of human dendritic cells Sci Rep, 8(1), 1765 DOI 10.1038/s41598-018-20173-y, PubMed 29379077
Sønderby IE, Gústafsson Ó, Doan NT, Hibar DP, Martin-Brevet S, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn N, Blangero J, Boomsma DI, Bralten J, Brattbak HR, Brodaty H, Brouwer RM, Bülow R, Calhoun V, Caspers S, Cavalleri G, Chen CH, Cichon S, Ciufolini Set al.(2018) Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia Mol Psychiatry, 25(3), 584-602 DOI 10.1038/s41380-018-0118-1, PubMed 30283035
Thunemann M, Lu Y, Liu X, Kılıç K, Desjardins M, Vandenberghe M, Sadegh S, Saisan PA, Cheng Q, Weldy KL, Lyu H, Djurovic S, Andreassen OA, Dale AM, Devor A, Kuzum D(2018) Deep 2-photon imaging and artifact-free optogenetics through transparent graphene microelectrode arrays Nat Commun, 9(1), 2035 DOI 10.1038/s41467-018-04457-5, PubMed 29789548
van der Meer D, Rokicki J, Kaufmann T, Córdova-Palomera A, Moberget T, Alnæs D, Bettella F, Frei O, Doan NT, Sønderby IE, Smeland OB, Agartz I, Bertolino A, Bralten J, Brandt CL, Buitelaar JK, Djurovic S, van Donkelaar M, Dørum ES, Espeseth T, Faraone SV, Fernández G, Fisher SE, Franke B, Haatveit Bet al.(2018) Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes Mol Psychiatry, 25(11), 3053-3065 DOI 10.1038/s41380-018-0262-7, PubMed 30279459
Witoelar A, Rongve A, Almdahl IS, Ulstein ID, Engvig A, White LR, Selbæk G, Stordal E, Andersen F, Brækhus A, Saltvedt I, Engedal K, Hughes T, Bergh S, Bråthen G, Bogdanovic N, Bettella F, Wang Y, Athanasiu L, Bahrami S, Le Hellard S, Giddaluru S, Dale AM, Sando SB, Steinberg Set al.(2018) Meta-analysis of Alzheimer's disease on 9,751 samples from Norway and IGAP study identifies four risk loci Sci Rep, 8(1), 18088 DOI 10.1038/s41598-018-36429-6, PubMed 30591712
Zuber V, Jönsson EG, Frei O, Witoelar A, Thompson WK, Schork AJ, Bettella F, Wang Y, Djurovic S, Smeland OB, Dieset I, Fanous AH, Desikan RS, Küry S, Bézieau S, Dale AM, Mills IG, Andreassen OA(2018) Identification of shared genetic variants between schizophrenia and lung cancer Sci Rep, 8(1), 674 DOI 10.1038/s41598-017-16481-4, PubMed 29330379
Publications 2017
Chen CH, Wang Y, Lo MT, Schork A, Fan CC, Holland D, Kauppi K, Smeland OB, Djurovic S, Sanyal N, Hibar DP, Thompson PM, Thompson WK, Andreassen OA, Dale AM(2017) Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure Sci Rep, 7(1), 15736 DOI 10.1038/s41598-017-15705-x, PubMed 29147026
Chen H, Ewing CM, Zheng S, Grindedaal EM, Cooney KA, Wiley K, Djurovic S, Andreassen OA, Axcrona K, Mills IG, Xu J, Maehle L, Fosså SD, Isaacs WB(2017) Genetic factors influencing prostate cancer risk in Norwegian men Prostate, 78(3), 186-192 DOI 10.1002/pros.23453, PubMed 29181843
Devor A, Andreassen OA, Wang Y, Mäki-Marttunen T, Smeland OB, Fan CC, Schork AJ, Holland D, Thompson WK, Witoelar A, Chen CH, Desikan RS, McEvoy LK, Djurovic S, Greengard P, Svenningsson P, Einevoll GT, Dale AM(2017) Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia Mol Psychiatry, 22(6), 792-801 DOI 10.1038/mp.2017.33, PubMed 28348379
Doan NT, Kaufmann T, Bettella F, Jørgensen KN, Brandt CL, Moberget T, Alnæs D, Douaud G, Duff E, Djurovic S, Melle I, Ueland T, Agartz I, Andreassen OA, Westlye LT(2017) Distinct multivariate brain morphological patterns and their added predictive value with cognitive and polygenic risk scores in mental disorders Neuroimage Clin, 15, 719-731 DOI 10.1016/j.nicl.2017.06.014, PubMed 28702349
Hibar DP, Adams HHH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beecham AH, Beiser A, Bernard M, Blanton SHet al.(2017) Novel genetic loci associated with hippocampal volume Nat Commun, 8, 13624 DOI 10.1038/ncomms13624, PubMed 28098162
Hoseth EZ, Ueland T, Dieset I, Birnbaum R, Shin JH, Kleinman JE, Hyde TM, Mørch RH, Hope S, Lekva T, Abraityte AJ, Michelsen AE, Melle I, Westlye LT, Ueland T, Djurovic S, Aukrust P, Weinberger DR, Andreassen OA(2017) A Study of TNF Pathway Activation in Schizophrenia and Bipolar Disorder in Plasma and Brain Tissue Schizophr Bull, 43(4), 881-890 DOI 10.1093/schbul/sbw183, PubMed 28049760
Johannessen J, Nærland T, Hope S, Torske T, Høyland AL, Strohmaier J, Heiberg A, Rietschel M, Djurovic S, Andreassen OA(2017) Parents' Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder-Data from a Norwegian Sample Int J Mol Sci, 18(5) DOI 10.3390/ijms18051078, PubMed 28524073
Lam M, Trampush JW, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KEet al.(2017) Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets Cell Rep, 21(9), 2597-2613 DOI 10.1016/j.celrep.2017.11.028, PubMed 29186694
Le Hellard S, Wang Y, Witoelar A, Zuber V, Bettella F, Hugdahl K, Espeseth T, Steen VM, Melle I, Desikan R, Schork AJ, Thompson WK, Dale AM, Djurovic S, Andreassen OA, Schizophrenia Working Group of the Psychiatric Genomics Consortium(2017) Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment Schizophr Bull, 43(3), 654-664 DOI 10.1093/schbul/sbw085, PubMed 27338279
Lu Y, Pouget JG, Andreassen OA, Djurovic S, Esko T, Hultman CM, Metspalu A, Milani L, Werge T, Sullivan PF(2017) Genetic risk scores and family history as predictors of schizophrenia in Nordic registers Psychol Med, 48(7), 1201-1208 DOI 10.1017/S0033291717002665, PubMed 28942743
Mellerup E, Andreassen OA, Bennike B, Dam H, Djurovic S, Jorgensen MB, Kessing LV, Koefoed P, Melle I, Mors O, Moeller GL(2017) Combinations of genetic variants associated with bipolar disorder PLoS One, 12(12), e0189739 DOI 10.1371/journal.pone.0189739, PubMed 29267373
Mørch RH, Dieset I, Faerden A, Hope S, Aas M, Nerhus M, Gardsjord ES, Haram M, Falk RS, Joa I, Morken G, Agartz I, Aukrust P, Djurovic S, Melle I, Ueland T, Andreassen OA(2017) Persistent increase in TNF and IL-1 markers in severe mental disorders suggests trait-related inflammation: a one year follow-up study Acta Psychiatr Scand, 136(4), 400-408 DOI 10.1111/acps.12783, PubMed 28815548
Olafsson S, Stridh P, Bos SD, Ingason A, Euesden J, Sulem P, Thorleifsson G, Gustafsson O, Johannesson A, Geirsson AJ, Thorsson AV, Sigurgeirsson B, Ludviksson BR, Olafsson E, Kristjansdottir H, Jonasson JG, Olafsson JH, Orvar KB, Benediktsson R, Bjarnason R, Kristjansdottir S, Gislason T, Valdimarsson T, Mikaelsdottir E, Sigurdsson Set al.(2017) Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations NPJ Genom Med, 2, 24 DOI 10.1038/s41525-017-0027-2, PubMed 29263835
Polushina T, Giddaluru S, Bettella F, Espeseth T, Lundervold AJ, Djurovic S, Cichon S, Hoffmann P, Nöthen MM, Steen VM, Andreassen OA, Le Hellard S(2017) Analysis of the joint effect of SNPs to identify independent loci and allelic heterogeneity in schizophrenia GWAS data Transl Psychiatry, 7(12), 1289 DOI 10.1038/s41398-017-0033-2, PubMed 29249828
Shadrin AA, Smeland OB, Zayats T, Schork AJ, Frei O, Bettella F, Witoelar A, Li W, Eriksen JA, Krull F, Djurovic S, Faraone SV, Reichborn-Kjennerud T, Thompson WK, Johansson S, Haavik J, Dale AM, Wang Y, Andreassen OA(2017) Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment J Am Acad Child Adolesc Psychiatry, 57(2), 86-95 DOI 10.1016/j.jaac.2017.11.013, PubMed 29413154
Smeland OB, Frei O, Kauppi K, Hill WD, Li W, Wang Y, Krull F, Bettella F, Eriksen JA, Witoelar A, Davies G, Fan CC, Thompson WK, Lam M, Lencz T, Chen CH, Ueland T, Jönsson EG, Djurovic S, Deary IJ, Dale AM, Andreassen OA, NeuroCHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology) Cognitive Working Group(2017) Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function JAMA Psychiatry, 74(10), 1065-1075 DOI 10.1001/jamapsychiatry.2017.1986, PubMed 28746715
Smeland OB, Wang Y, Lo MT, Li W, Frei O, Witoelar A, Tesli M, Hinds DA, Tung JY, Djurovic S, Chen CH, Dale AM, Andreassen OA(2017) Identification of genetic loci shared between schizophrenia and the Big Five personality traits Sci Rep, 7(1), 2222 DOI 10.1038/s41598-017-02346-3, PubMed 28533504
Srinivasan S, Bettella F, Hassani S, Wang Y, Witoelar A, Schork AJ, Thompson WK, Collier DA, Desikan RS, Melle I, Dale AM, Djurovic S, Andreassen OA(2017) Probing the Association between Early Evolutionary Markers and Schizophrenia PLoS One, 12(1), e0169227 DOI 10.1371/journal.pone.0169227, PubMed 28081145
Trampush JW, Yang ML, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KEet al.(2017) GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium Mol Psychiatry, 22(3), 336-345 DOI 10.1038/mp.2016.244, PubMed 28093568
Trampush JW, Yang MLZ, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KEet al.(2017) GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium Mol Psychiatry, 22(11), 1651-1652 DOI 10.1038/mp.2017.197, PubMed 29068436
Witoelar A, Jansen IE, Wang Y, Desikan RS, Gibbs JR, Blauwendraat C, Thompson WK, Hernandez DG, Djurovic S, Schork AJ, Bettella F, Ellinghaus D, Franke A, Lie BA, McEvoy LK, Karlsen TH, Lesage S, Morris HR, Brice A, Wood NW, Heutink P, Hardy J, Singleton AB, Dale AM, Gasser Tet al.(2017) Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases JAMA Neurol, 74(7), 780-792 DOI 10.1001/jamaneurol.2017.0469, PubMed 28586827
Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, Treutlein J, Degenhardt F, Forstner AJ, Heilmann-Heimbach S, Dietl L, Schwarze CE, Schendel D, Strohmaier J, Abdellaoui A, Adolfsson R, Air TM, Akil H, Alda M, Alliey-Rodriguez N, Andreassen OA, Babadjanova G, Bass NJ, Bauer M, Baune BTet al.(2017) Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia Transl Psychiatry, 7(6), e1155 DOI 10.1038/tp.2017.115, PubMed 28632202
Aas M, Melle I, Bettella F, Djurovic S, Le Hellard S, Bjella T, Ringen PA, Lagerberg TV, Smeland OB, Agartz I, Andreassen OA, Tesli M(2017) Psychotic patients who used cannabis frequently before illness onset have higher genetic predisposition to schizophrenia than those who did not Psychol Med, 48(1), 43-49 DOI 10.1017/S0033291717001209, PubMed 28967348
Publications 2016
Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard Met al.(2016) Novel genetic loci underlying human intracranial volume identified through genome-wide association Nat Neurosci, 19(12), 1569-1582 DOI 10.1038/nn.4398, PubMed 27694991
Athanasiu L, Giddaluru S, Fernandes C, Christoforou A, Reinvang I, Lundervold AJ, Nilsson LG, Kauppi K, Adolfsson R, Eriksson E, Sundet K, Djurovic S, Espeseth T, Nyberg L, Steen VM, Andreassen OA, Le Hellard S(2016) A genetic association study of CSMD1 and CSMD2 with cognitive function Brain Behav Immun, 61, 209-216 DOI 10.1016/j.bbi.2016.11.026, PubMed 27890662
Falk A, Heine VM, Harwood AJ, Sullivan PF, Peitz M, Brüstle O, Shen S, Sun YM, Glover JC, Posthuma D, Djurovic S(2016) Modeling psychiatric disorders: from genomic findings to cellular phenotypes Mol Psychiatry, 21(9), 1167-79 DOI 10.1038/mp.2016.89, PubMed 27240529
Falk A, Heine VM, Harwood AJ, Sullivan PF, Peitz M, Brüstle O, Shen S, Sun YM, Glover JC, Posthuma D, Djurovic S(2016) Modeling psychiatric disorders: from genomic findings to cellular phenotypes Mol Psychiatry, 21(9), 1321 DOI 10.1038/mp.2016.100, PubMed 27324182
Gunnarsson B, Jónsdóttir GA, Björnsdóttir G, Konte B, Sulem P, Kristmundsdóttir S, Kehr B, Gústafsson Ó, Helgason H, Iordache PD, Ólafsson S, Frigge ML, Þorleifsson G, Arnarsdóttir S, Stefánsdóttir B, Giegling I, Djurovic S, Sundet KS, Espeseth T, Melle I, Hartmann AM, Thorsteinsdottir U, Kong A, Guðbjartsson DF, Ettinger Uet al.(2016) A sequence variant associating with educational attainment also affects childhood cognition Sci Rep, 6, 36189 DOI 10.1038/srep36189, PubMed 27811963
Haram M, Bettella F, Brandt CL, Quintana DS, Nerhus M, Bjella T, Djurovic S, Westlye LT, Andreassen OA, Melle I, Tesli M(2016) Contribution of oxytocin receptor polymorphisms to amygdala activation in schizophrenia spectrum disorders BJPsych Open, 2(6), 353-358 DOI 10.1192/bjpo.bp.116.003376, PubMed 27847593
Johannessen J, Nærland T, Bloss C, Rietschel M, Strohmaier J, Gjevik E, Heiberg A, Djurovic S, Andreassen OA(2016) Parents' attitudes toward genetic research in autism spectrum disorder Psychiatr Genet, 26(2), 74-80 DOI 10.1097/YPG.0000000000000121, PubMed 26867185
Kaufmann T, Alnæs D, Brandt CL, Doan NT, Kauppi K, Bettella F, Lagerberg TV, Berg AO, Djurovic S, Agartz I, Melle IS, Ueland T, Andreassen OA, Westlye LT(2016) Task modulations and clinical manifestations in the brain functional connectome in 1615 fMRI datasets Neuroimage, 147, 243-252 DOI 10.1016/j.neuroimage.2016.11.073, PubMed 27916665
Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, Antaki D, Shetty A, Holmans PA, Pinto D, Gujral M, Brandler WM, Malhotra D, Wang Z, Fajarado KVF, Maile MS, Ripke S, Agartz I, Albus M, Alexander M, Amin F, Atkins J, Bacanu SA, Belliveau RA, Bergen SEet al.(2016) Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects Nat Genet, 49(1), 27-35 DOI 10.1038/ng.3725, PubMed 27869829
Mehta D, Tropf FC, Gratten J, Bakshi A, Zhu Z, Bacanu SA, Hemani G, Magnusson PK, Barban N, Esko T, Metspalu A, Snieder H, Mowry BJ, Kendler KS, Yang J, Visscher PM, McGrath JJ, Mills MC, Wray NR, Lee SH, Schizophrenia Working Group of the Psychiatric Genomics Consortium, LifeLines Cohort Study, and TwinsUK, Andreassen OA, Bramon E, Bruggeman R, Buxbaum JDet al.(2016) Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women JAMA Psychiatry, 73(5), 497-505 DOI 10.1001/jamapsychiatry.2016.0129, PubMed 27007234
Mäki-Marttunen T, Halnes G, Devor A, Witoelar A, Bettella F, Djurovic S, Wang Y, Einevoll GT, Andreassen OA, Dale AM(2016) Functional Effects of Schizophrenia-Linked Genetic Variants on Intrinsic Single-Neuron Excitability: A Modeling Study Biol Psychiatry Cogn Neurosci Neuroimaging, 1(1), 49-59 DOI 10.1016/j.bpsc.2015.09.002, PubMed 26949748
Mørch RH, Dieset I, Færden A, Hope S, Aas M, Nerhus M, Gardsjord ES, Joa I, Morken G, Agartz I, Aukrust P, Djurovic S, Melle I, Ueland T, Andreassen OA(2016) Inflammatory evidence for the psychosis continuum model Psychoneuroendocrinology, 67, 189-97 DOI 10.1016/j.psyneuen.2016.02.011, PubMed 26923849
Peng Q, Schork A, Bartsch H, Lo MT, Panizzon MS, Pediatric Imaging, Neurocognition and Genetics Study, Alzheimer’s Disease Neuroimaging Initiative, Westlye LT, Kremen WS, Jernigan TL, Le Hellard S, Steen VM, Espeseth T, Huentelman M, Håberg AK, Agartz I, Djurovic S, Andreassen OA, Dale AM, Schork NJ, Chen CH(2016) Conservation of Distinct Genetically-Mediated Human Cortical Pattern PLoS Genet, 12(7), e1006143 DOI 10.1371/journal.pgen.1006143, PubMed 27459196
Szabo A, Kovacs A, Riba J, Djurovic S, Rajnavolgyi E, Frecska E(2016) The Endogenous Hallucinogen and Trace Amine N,N-Dimethyltryptamine (DMT) Displays Potent Protective Effects against Hypoxia via Sigma-1 Receptor Activation in Human Primary iPSC-Derived Cortical Neurons and Microglia-Like Immune Cells Front Neurosci, 10, 423 DOI 10.3389/fnins.2016.00423, PubMed 27683542
Tesli M, Wirgenes KV, Hughes T, Bettella F, Athanasiu L, Hoseth ES, Nerhus M, Lagerberg TV, Steen NE, Agartz I, Melle I, Dieset I, Djurovic S, Andreassen OA(2016) VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls Br J Psychiatry, 209(2), 114-20 DOI 10.1192/bjp.bp.115.161950, PubMed 26941264
Uhlirova H, Kılıç K, Tian P, Sakadžić S, Gagnon L, Thunemann M, Desjardins M, Saisan PA, Nizar K, Yaseen MA, Hagler DJ, Vandenberghe M, Djurovic S, Andreassen OA, Silva GA, Masliah E, Kleinfeld D, Vinogradov S, Buxton RB, Einevoll GT, Boas DA, Dale AM, Devor A(2016) The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements Philos Trans R Soc Lond B Biol Sci, 371(1705) DOI 10.1098/rstb.2015.0356, PubMed 27574309
Uhlirova H, Kılıç K, Tian P, Thunemann M, Desjardins M, Saisan PA, Sakadžić S, Ness TV, Mateo C, Cheng Q, Weldy KL, Razoux F, Vandenberghe M, Cremonesi JA, Ferri CG, Nizar K, Sridhar VB, Steed TC, Abashin M, Fainman Y, Masliah E, Djurovic S, Andreassen OA, Silva GA, Boas DAet al.(2016) Cell type specificity of neurovascular coupling in cerebral cortex Elife, 5 DOI 10.7554/eLife.14315, PubMed 27244241
Wang Y, Bos SD, Harbo HF, Thompson WK, Schork AJ, Bettella F, Witoelar A, Lie BA, Li W, McEvoy LK, Djurovic S, Desikan RS, Dale AM, Andreassen OA(2016) Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors Mult Scler, 22(14), 1783-1793 DOI 10.1177/1352458516635873, PubMed 26920376
Wang Y, Thompson WK, Schork AJ, Holland D, Chen CH, Bettella F, Desikan RS, Li W, Witoelar A, Zuber V, Devor A, Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium, Enhancing Neuro Imaging Genetics through Meta Analysis Consortium, Nöthen MM, Rietschel M, Chen Q, Werge T, Cichon S, Weinberger DR, Djurovic S, O'Donovan M, Visscher PM, Andreassen OA, Dale AM(2016) Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS PLoS Genet, 12(1), e1005803 DOI 10.1371/journal.pgen.1005803, PubMed 26808560
Zuber V, Marconett CN, Shi J, Hua X, Wheeler W, Yang C, Song L, Dale AM, Laplana M, Risch A, Witoelar A, Thompson WK, Schork AJ, Bettella F, Wang Y, Djurovic S, Zhou B, Borok Z, van der Heijden HF, de Graaf J, Swinkels D, Aben KK, McKay J, Hung RJ, Bikeböller Het al.(2016) Pleiotropic Analysis of Lung Cancer and Blood Triglycerides J Natl Cancer Inst, 108(12) DOI 10.1093/jnci/djw167, PubMed 27565901
Publications 2015
Aminoff SR, Tesli M, Bettella F, Aas M, Lagerberg TV, Djurovic S, Andreassen OA, Melle I(2015) Polygenic risk scores in bipolar disorder subgroups J Affect Disord, 183, 310-4 DOI 10.1016/j.jad.2015.05.021, PubMed 26047958
Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM(2015) Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms PLoS One, 10(4), e0123057 DOI 10.1371/journal.pone.0123057, PubMed 25853426
Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM(2015) Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms PLoS One, 10(5), e0128048 DOI 10.1371/journal.pone.0128048, PubMed 25978331
Andreassen OA, Thompson WK, Schork AJ, Ripke S, Mattingsdal M, Kelsoe JR, Kendler KS, O'Donovan MC, Rujescu D, Werge T, Sklar P, Psychiatric Genomics Consortium (PGC), Bipolar Disorder and Schizophrenia Working Groups, Roddey JC, Chen CH, McEvoy L, Desikan RS, Djurovic S, Dale AM(2015) Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate PLoS Genet, 11(11), e1005544 DOI 10.1371/journal.pgen.1005544, PubMed 26540268
Athanasiu L, Smorr LL, Tesli M, Røssberg JI, Sønderby IE, Spigset O, Djurovic S, Andreassen OA(2015) Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs J Psychopharmacol, 29(8), 884-91 DOI 10.1177/0269881115584469, PubMed 25944848
Chen CH, Peng Q, Schork AJ, Lo MT, Fan CC, Wang Y, Desikan RS, Bettella F, Hagler DJ, Pediatric Imaging, Neurocognition and Genetics Study, Alzheimer’s Disease Neuroimaging Initiative, Westlye LT, Kremen WS, Jernigan TL, Le Hellard S, Steen VM, Espeseth T, Huentelman M, Håberg AK, Agartz I, Djurovic S, Andreassen OA, Schork N, Dale AM, Pediatric Imaging Neurocognition and Genetics Studyet al.(2015) Large-scale genomics unveil polygenic architecture of human cortical surface area Nat Commun, 6, 7549 DOI 10.1038/ncomms8549, PubMed 26189703
Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, Chasman DI, McEvoy LK, Holland D, Chen CH, Karow DS, Brewer JB, Hess CP, Williams J, Sims R, O'Donovan MC, Choi SH, Bis JC, Ikram MA, Gudnason V, DeStefano AL, van der Lee SJ, Psaty BM, van Duijn CM, Launer Let al.(2015) Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease Circulation, 131(23), 2061-2069 DOI 10.1161/CIRCULATIONAHA.115.015489, PubMed 25862742
Desikan RS, Schork AJ, Wang Y, Witoelar A, Sharma M, McEvoy LK, Holland D, Brewer JB, Chen CH, Thompson WK, Harold D, Williams J, Owen MJ, O'Donovan MC, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Schellenberg GD, Heutink P, Singleton AB, Brice A, Wood NW, Hardy J, Martinez Met al.(2015) Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus Mol Psychiatry, 20(12), 1588-95 DOI 10.1038/mp.2015.6, PubMed 25687773
Goulart LF, Bettella F, Sønderby IE, Schork AJ, Thompson WK, Mattingsdal M, Steen VM, Zuber V, Wang Y, Dale AM, PRACTICAL/ELLIPSE consortium, Andreassen OA, Djurovic S(2015) MicroRNAs enrichment in GWAS of complex human phenotypes BMC Genomics, 16(1), 304 DOI 10.1186/s12864-015-1513-5, PubMed 25884492
Haram M, Tesli M, Bettella F, Djurovic S, Andreassen OA, Melle I(2015) Association between Genetic Variation in the Oxytocin Receptor Gene and Emotional Withdrawal, but not between Oxytocin Pathway Genes and Diagnosis in Psychotic Disorders Front Hum Neurosci, 9, 9 DOI 10.3389/fnhum.2015.00009, PubMed 25667571
Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivières S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, Bralten J, Brown AA, Chakravarty MM, Chen Q, Ching CR, Cuellar-Partida G, den Braber A, Giddaluru S, Goldman AL, Grimm Oet al.(2015) Common genetic variants influence human subcortical brain structures Nature, 520(7546), 224-9 DOI 10.1038/nature14101, PubMed 25607358
Hoeffding LK, Duong LT, Ingason A, Rosengren A, Sorbanski E, Witt SH, Djurovic S, Andreassen OA, Hansen T, Werge T, Rasmussen HB(2015) Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders Nord J Psychiatry, 70(4), 276-9 DOI 10.3109/08039488.2015.1095944, PubMed 26559242
Hope S, Hoseth E, Dieset I, Mørch RH, Aas M, Aukrust P, Djurovic S, Melle I, Ueland T, Agartz I, Ueland T, Westlye LT, Andreassen OA(2015) Inflammatory markers are associated with general cognitive abilities in schizophrenia and bipolar disorder patients and healthy controls Schizophr Res, 165(2-3), 188-94 DOI 10.1016/j.schres.2015.04.004, PubMed 25956633
Howrigan DP, Simonson MA, Davies G, Harris SE, Tenesa A, Starr JM, Liewald DC, Deary IJ, McRae A, Wright MJ, Montgomery GW, Hansell N, Martin NG, Payton A, Horan M, Ollier WE, Abdellaoui A, Boomsma DI, DeRosse P, Knowles EE, Glahn DC, Djurovic S, Melle I, Andreassen OA, Christoforou Aet al.(2015) Genome-wide autozygosity is associated with lower general cognitive ability Mol Psychiatry, 21(6), 837-43 DOI 10.1038/mp.2015.120, PubMed 26390830
Hughes T, Hansson L, Sønderby IE, Athanasiu L, Zuber V, Tesli M, Song J, Hultman CM, Bergen SE, Landén M, Melle I, Andreassen OA, Djurovic S(2015) A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia Biol Psychiatry, 80(4), 323-330 DOI 10.1016/j.biopsych.2015.09.021, PubMed 26682468
Johansson MM, Van Geystelen A, Larmuseau MH, Djurovic S, Andreassen OA, Agartz I, Jazin E(2015) Microarray Analysis of Copy Number Variants on the Human Y Chromosome Reveals Novel and Frequent Duplications Overrepresented in Specific Haplogroups PLoS One, 10(8), e0137223 DOI 10.1371/journal.pone.0137223, PubMed 26322892
LeBlanc M, Zuber V, Andreassen BK, Witoelar A, Zeng L, Bettella F, Wang Y, McEvoy LK, Thompson WK, Schork AJ, Reppe S, Barrett-Connor E, Ligthart S, Dehghan A, Gautvik KM, Nelson CP, Schunkert H, Samani NJ, CARDIoGRAM Consortium, Ridker PM, Chasman DI, Aukrust P, Djurovic S, Frigessi A, Desikan RSet al.(2015) Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors Circ Res, 118(1), 83-94 DOI 10.1161/CIRCRESAHA.115.306629, PubMed 26487741
Lee SH, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AA, Ripke S, Andreassen OA, Frisell T, Gusev A, Hu X, Karlsson R, Mantzioris VX, McGrath JJ, Mehta D, Stahl EA, Zhao Q, Kendler KS, Sullivan PF, Price AL, O'Donovan M, Okada Y, Mowry BJ, Raychaudhuri S, Wray NR, Schizophrenia Working Group of the Psychiatric Genomics Consortium and Rheumatoid Arthritis Consortium Internationalet al.(2015) New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis Int J Epidemiol, 44(5), 1706-21 DOI 10.1093/ije/dyv136, PubMed 26286434
Mellerup E, Andreassen OA, Bennike B, Dam H, Djurovic S, Hansen T, Jorgensen MB, Kessing LV, Koefoed P, Melle I, Mors O, Werge T, Moeller GL(2015) Combinations of Genetic Data Present in Bipolar Patients, but Absent in Control Persons PLoS One, 10(11), e0143432 DOI 10.1371/journal.pone.0143432, PubMed 26587987
Reppe S, Wang Y, Thompson WK, McEvoy LK, Schork AJ, Zuber V, LeBlanc M, Bettella F, Mills IG, Desikan RS, Djurovic S, Gautvik KM, Dale AM, Andreassen OA, GEFOS Consortium(2015) Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci PLoS One, 10(12), e0144531 DOI 10.1371/journal.pone.0144531, PubMed 26695485
Srinivasan S, Bettella F, Mattingsdal M, Wang Y, Witoelar A, Schork AJ, Thompson WK, Zuber V, Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, Winsvold BS, Zwart JA, Collier DA, Desikan RS, Melle I, Werge T, Dale AM, Djurovic S, Andreassen OA(2015) Genetic Markers of Human Evolution Are Enriched in Schizophrenia Biol Psychiatry, 80(4), 284-292 DOI 10.1016/j.biopsych.2015.10.009, PubMed 26681495
Steinberg S, Stefansson H, Jonsson T, Johannsdottir H, Ingason A, Helgason H, Sulem P, Magnusson OT, Gudjonsson SA, Unnsteinsdottir U, Kong A, Helisalmi S, Soininen H, Lah JJ, DemGene, Aarsland D, Fladby T, Ulstein ID, Djurovic S, Sando SB, White LR, Knudsen GP, Westlye LT, Selbæk G, Giegling Iet al.(2015) Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease Nat Genet, 47(5), 445-7 DOI 10.1038/ng.3246, PubMed 25807283
Tesli M, Kauppi K, Bettella F, Brandt CL, Kaufmann T, Espeseth T, Mattingsdal M, Agartz I, Melle I, Djurovic S, Westlye LT, Andreassen OA(2015) Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder PLoS One, 10(7), e0134202 DOI 10.1371/journal.pone.0134202, PubMed 26222050
Trampush JW, Lencz T, Knowles E, Davies G, Guha S, Pe'er I, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, Mukherjee S, DeRosse P, Lundervold A, Steen VM, John M, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte Bet al.(2015) Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment Am J Med Genet B Neuropsychiatr Genet, 168B(5), 363-73 DOI 10.1002/ajmg.b.32319, PubMed 25951819
Zayats T, Athanasiu L, Sonderby I, Djurovic S, Westlye LT, Tamnes CK, Fladby T, Aase H, Zeiner P, Reichborn-Kjennerud T, Knappskog PM, Knudsen GP, Andreassen OA, Johansson S, Haavik J(2015) Genome-wide analysis of attention deficit hyperactivity disorder in Norway PLoS One, 10(4), e0122501 DOI 10.1371/journal.pone.0122501, PubMed 25875332
Publications 2014
Andreassen OA, Harbo HF, Wang Y, Thompson WK, Schork AJ, Mattingsdal M, Zuber V, Bettella F, Ripke S, Kelsoe JR, Kendler KS, O'Donovan MC, Sklar P, Psychiatric Genomics Consortium (PGC) Bipolar Disorder and Schizophrenia Work Groups, International Multiple Sclerosis Genetics Consortium (IMSGC), McEvoy LK, Desikan RS, Lie BA, Djurovic S, Dale AM(2014) Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci Mol Psychiatry, 20(2), 207-14 DOI 10.1038/mp.2013.195, PubMed 24468824
Andreassen OA, McEvoy LK, Thompson WK, Wang Y, Reppe S, Schork AJ, Zuber V, Barrett-Connor E, Gautvik K, Aukrust P, Karlsen TH, Djurovic S, Desikan RS, Dale AM, International Consortium for Blood Pressure Genome-Wide Association Studies, Genetic Factors for Osteoporosis Consortium(2014) Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes Hypertension, 63(4), 819-26 DOI 10.1161/HYPERTENSIONAHA.113.02077, PubMed 24396023
Andreassen OA, Zuber V, Thompson WK, Schork AJ, Bettella F, PRACTICAL Consortium, CRUK GWAS, Djurovic S, Desikan RS, Mills IG, Dale AM(2014) Shared common variants in prostate cancer and blood lipids Int J Epidemiol, 43(4), 1205-14 DOI 10.1093/ije/dyu090, PubMed 24786909
Christoforou A, Espeseth T, Davies G, Fernandes CP, Giddaluru S, Mattheisen M, Tenesa A, Harris SE, Liewald DC, Payton A, Ollier W, Horan M, Pendleton N, Haggarty P, Djurovic S, Herms S, Hoffman P, Cichon S, Starr JM, Lundervold A, Reinvang I, Steen VM, Deary IJ, Le Hellard S(2014) GWAS-based pathway analysis differentiates between fluid and crystallized intelligence Genes Brain Behav, 13(7), 663-74 DOI 10.1111/gbb.12152, PubMed 24975275
Dieset I, Haukvik UK, Melle I, Røssberg JI, Ueland T, Hope S, Dale AM, Djurovic S, Aukrust P, Agartz I, Andreassen OA(2014) Association between altered brain morphology and elevated peripheral endothelial markers--implications for psychotic disorders Schizophr Res, 161(2-3), 222-8 DOI 10.1016/j.schres.2014.11.006, PubMed 25433965
Haram M, Tesli M, Dieset I, Steen NE, Røssberg JI, Djurovic S, Andreassen OA, Melle I(2014) An attempt to identify single nucleotide polymorphisms contributing to possible relationships between personality traits and oxytocin-related genes Neuropsychobiology, 69(1), 25-30 DOI 10.1159/000356965, PubMed 24458227
Kauppi K, Westlye LT, Tesli M, Bettella F, Brandt CL, Mattingsdal M, Ueland T, Espeseth T, Agartz I, Melle I, Djurovic S, Andreassen OA(2014) Polygenic risk for schizophrenia associated with working memory-related prefrontal brain activation in patients with schizophrenia and healthy controls Schizophr Bull, 41(3), 736-43 DOI 10.1093/schbul/sbu152, PubMed 25392519
Tesli M, Espeseth T, Bettella F, Mattingsdal M, Aas M, Melle I, Djurovic S, Andreassen OA(2014) Polygenic risk score and the psychosis continuum model Acta Psychiatr Scand, 130(4), 311-7 DOI 10.1111/acps.12307, PubMed 24961959
Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, Almasy L, Almeida J, Alpert K, Andreasen NC, Andreassen OA, Apostolova LG, Appel K, Armstrong NJ, Aribisala B, Bastin MEet al.(2014) The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data Brain Imaging Behav, 8(2), 153-82 DOI 10.1007/s11682-013-9269-5, PubMed 24399358
Wirgenes KV, Tesli M, Inderhaug E, Athanasiu L, Agartz I, Melle I, Hughes T, Andreassen OA, Djurovic S(2014) ANK3 gene expression in bipolar disorder and schizophrenia Br J Psychiatry, 205(3), 244-5 DOI 10.1192/bjp.bp.114.145433, PubMed 24809399
Zai CC, Manchia M, Sønderby IE, Yilmaz Z, De Luca V, Tiwari AK, Squassina A, Zai GC, Shaikh SA, Strauss J, King N, Le Foll B, Kaplan AS, Finseth PI, Vaaler AE, Djurovic S, Andreassen OA, Vincent JB, Kennedy JL(2014) Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders World J Biol Psychiatry, 16(3), 171-9 DOI 10.3109/15622975.2014.953011, PubMed 25264289
Aas M, Haukvik UK, Djurovic S, Tesli M, Athanasiu L, Bjella T, Hansson L, Cattaneo A, Agartz I, Andreassen OA, Melle I(2014) Interplay between childhood trauma and BDNF val66met variants on blood BDNF mRNA levels and on hippocampus subfields volumes in schizophrenia spectrum and bipolar disorders J Psychiatr Res, 59, 14-21 DOI 10.1016/j.jpsychires.2014.08.011, PubMed 25246365
Publications 2013
Aberg KA, Liu Y, Bukszár J, McClay JL, Khachane AN, Andreassen OA, Blackwood D, Corvin A, Djurovic S, Gurling H, Ophoff R, Pato CN, Pato MT, Riley B, Webb T, Kendler K, O'Donovan M, Craddock N, Kirov G, Owen M, Rujescu D, St Clair D, Werge T, Hultman CM, Delisi LEet al.(2013) A comprehensive family-based replication study of schizophrenia genes JAMA Psychiatry, 70(6), 573-81 DOI 10.1001/jamapsychiatry.2013.288, PubMed 23894747
Andreassen OA, Djurovic S, Thompson WK, Schork AJ, Kendler KS, O'Donovan MC, Rujescu D, Werge T, van de Bunt M, Morris AP, McCarthy MI, International Consortium for Blood Pressure GWAS, Diabetes Genetics Replication and Meta-analysis Consortium, Psychiatric Genomics Consortium Schizophrenia Working Group, Roddey JC, McEvoy LK, Desikan RS, Dale AM(2013) Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors Am J Hum Genet, 92(2), 197-209 DOI 10.1016/j.ajhg.2013.01.001, PubMed 23375658
Andreassen OA, Thompson WK, Schork AJ, Ripke S, Mattingsdal M, Kelsoe JR, Kendler KS, O'Donovan MC, Rujescu D, Werge T, Sklar P, Psychiatric Genomics Consortium (PGC), Bipolar Disorder and Schizophrenia Working Groups, Roddey JC, Chen CH, McEvoy L, Desikan RS, Djurovic S, Dale AM(2013) Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate PLoS Genet, 9(4), e1003455 DOI 10.1371/journal.pgen.1003455, PubMed 23637625
Bergmann O, Haukvik UK, Brown AA, Rimol LM, Hartberg CB, Athanasiu L, Melle I, Djurovic S, Andreassen OA, Dale AM, Agartz I(2013) ZNF804A and cortical thickness in schizophrenia and bipolar disorder Psychiatry Res, 212(2), 154-7 DOI 10.1016/j.pscychresns.2013.01.007, PubMed 23562677
Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, Andreassen OA, Anjorin A, Anney R, Anttila V, Arking DE, Asherson P, Azevedo MH, Backlund L, Badner JA, Bailey AJet al.(2013) Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs Nat Genet, 45(9), 984-94 DOI 10.1038/ng.2711, PubMed 23933821
Fernandes CP, Christoforou A, Giddaluru S, Ersland KM, Djurovic S, Mattheisen M, Lundervold AJ, Reinvang I, Nöthen MM, Rietschel M, Ophoff RA, Genetic Risk and Outcome of Psychosis (GROUP), Hofman A, Uitterlinden AG, Werge T, Cichon S, Espeseth T, Andreassen OA, Steen VM, Le Hellard S(2013) A genetic deconstruction of neurocognitive traits in schizophrenia and bipolar disorder PLoS One, 8(12), e81052 DOI 10.1371/journal.pone.0081052, PubMed 24349030
Finseth PI, Sønderby IE, Djurovic S, Agartz I, Malt UF, Melle I, Morken G, Andreassen OA, Vaaler AE, Tesli M(2013) Association analysis between suicidal behaviour and candidate genes of bipolar disorder and schizophrenia J Affect Disord, 163, 110-4 DOI 10.1016/j.jad.2013.12.018, PubMed 24461634
Hibar DP, Medland SE, Stein JL, Kim S, Shen L, Saykin AJ, de Zubicaray GI, McMahon KL, Montgomery GW, Martin NG, Wright MJ, Djurovic S, Agartz IA, Andreassen OA, Thompson PM(2013) Genetic clustering on the hippocampal surface for genome-wide association studies Med Image Comput Comput Assist Interv, 16(Pt 2), 690-7 DOI 10.1007/978-3-642-40763-5_85, PubMed 24579201
Hibar DP, Medland SE, Stein JL, Kim S, Shen L, Saykin AJ, de Zubicaray GI, McMahon KL, Montgomery GW, Martin NG, Wright MJ, Djurovic S, Agartz IA, Andreassen OA, Thompson PM(2013) Genetic Clustering on the Hippocampal Surface for Genome-Wide Association Studies LECT NOTES COMPUT SC, 8150, 690-697
Lencz T, Knowles E, Davies G, Guha S, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, Mukherjee S, DeRosse P, Lundervold A, Steen VM, John M, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Ikeda M, Roussos Pet al.(2013) Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT) Mol Psychiatry, 19(2), 168-74 DOI 10.1038/mp.2013.166, PubMed 24342994
Ruderfer DM, Fanous AH, Ripke S, McQuillin A, Amdur RL, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Gejman PV, O'Donovan MC, Andreassen OA, Djurovic S, Hultman CM, Kelsoe JR, Jamain S, Landén M, Leboyer M, Nimgaonkar V, Nurnberger J, Smoller JW, Craddock N, Corvin A, Sullivan PF, Holmans P, Sklar Pet al.(2013) Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia Mol Psychiatry, 19(9), 1017-1024 DOI 10.1038/mp.2013.138, PubMed 24280982
Tesli M, Egeland R, Sønderby IE, Haukvik UK, Bettella F, Hibar DP, Thompson PM, Rimol LM, Melle I, Agartz I, Djurovic S, Andreassen OA(2013) No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes J Affect Disord, 151(1), 291-7 DOI 10.1016/j.jad.2013.06.008, PubMed 23820096
Tesli M, Skatun KC, Ousdal OT, Brown AA, Thoresen C, Agartz I, Melle I, Djurovic S, Jensen J, Andreassen OA(2013) CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls PLoS One, 8(2), e56970 DOI 10.1371/journal.pone.0056970, PubMed 23437284
Aas M, Haukvik UK, Djurovic S, Bergmann Ø, Athanasiu L, Tesli MS, Hellvin T, Steen NE, Agartz I, Lorentzen S, Sundet K, Andreassen OA, Melle I(2013) BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses Prog Neuropsychopharmacol Biol Psychiatry, 46, 181-8 DOI 10.1016/j.pnpbp.2013.07.008, PubMed 23876786
Publications 2012
Athanasiu L, Brown AA, Birkenaes AB, Mattingsdal M, Agartz I, Melle I, Steen VM, Andreassen OA, Djurovic S(2012) Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study Psychiatry Res, 197(3), 327-36 DOI 10.1016/j.psychres.2011.12.036, PubMed 22417934
Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM, Alzheimer's Disease Neuroimaging Initiativeet al.(2012) Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans Proc Natl Acad Sci U S A, 109(10), 3985-90 DOI 10.1073/pnas.1105829109, PubMed 22343285
Brown AA, Jensen J, Nikolova YS, Djurovic S, Agartz I, Server A, Ferrell RE, Manuck SB, Mattingsdal M, Melle I, Hariri AR, Frigessi A, Andreassen OA(2012) Genetic variants affecting the neural processing of human facial expressions: evidence using a genome-wide functional imaging approach Transl Psychiatry, 2(7), e143 DOI 10.1038/tp.2012.67, PubMed 22828495
Christoforou A, Dondrup M, Mattingsdal M, Mattheisen M, Giddaluru S, Nöthen MM, Rietschel M, Cichon S, Djurovic S, Andreassen OA, Jonassen I, Steen VM, Puntervoll P, Le Hellard S(2012) Linkage-disequilibrium-based binning affects the interpretation of GWASs Am J Hum Genet, 90(4), 727-33 DOI 10.1016/j.ajhg.2012.02.025, PubMed 22444669
Dieset I, Djurovic S, Tesli M, Hope S, Mattingsdal M, Michelsen A, Joa I, Larsen TK, Agartz I, Melle I, Røssberg JI, Aukrust P, Andreassen OA, Ueland T(2012) Up-regulation of NOTCH4 gene expression in bipolar disorder Am J Psychiatry, 169(12), 1292-300 DOI 10.1176/appi.ajp.2012.11091431, PubMed 23212060
Ersland KM, Christoforou A, Stansberg C, Espeseth T, Mattheisen M, Mattingsdal M, Hardarson GA, Hansen T, Fernandes CP, Giddaluru S, Breuer R, Strohmaier J, Djurovic S, Nöthen MM, Rietschel M, Lundervold AJ, Werge T, Cichon S, Andreassen OA, Reinvang I, Steen VM, Le Hellard S(2012) Gene-based analysis of regionally enriched cortical genes in GWAS data sets of cognitive traits and psychiatric disorders PLoS One, 7(2), e31687 DOI 10.1371/journal.pone.0031687, PubMed 22384057
Håvik B, Degenhardt FA, Johansson S, Fernandes CP, Hinney A, Scherag A, Lybæk H, Djurovic S, Christoforou A, Ersland KM, Giddaluru S, O'Donovan MC, Owen MJ, Craddock N, Mühleisen TW, Mattheisen M, Schimmelmann BG, Renner T, Warnke A, Herpertz-Dahlmann B, Sinzig J, Albayrak Ö, Rietschel M, Nöthen MM, Bramham CRet al.(2012) DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder PLoS One, 7(4), e35424 DOI 10.1371/journal.pone.0035424, PubMed 22539971
Jonsson T, Stefansson H, Steinberg S, Jonsdottir I, Jonsson PV, Snaedal J, Bjornsson S, Huttenlocher J, Levey AI, Lah JJ, Rujescu D, Hampel H, Giegling I, Andreassen OA, Engedal K, Ulstein I, Djurovic S, Ibrahim-Verbaas C, Hofman A, Ikram MA, van Duijn CM, Thorsteinsdottir U, Kong A, Stefansson K(2012) Variant of TREM2 associated with the risk of Alzheimer's disease N Engl J Med, 368(2), 107-16 DOI 10.1056/NEJMoa1211103, PubMed 23150908
Jönsson EG, Saetre P, Nyholm H, Djurovic S, Melle I, Andreassen OA, Skjødt C, Thygesen JH, Werge T, Hall H, Agartz I, Terenius L(2012) Lack of association between the regulator of G-protein signaling 4 (RGS4) rs951436 polymorphism and schizophrenia Psychiatr Genet, 22(5), 263-4 DOI 10.1097/YPG.0b013e32834f3558, PubMed 22157635
Kähler AK, Rimol LM, Brown AA, Djurovic S, Hartberg CB, Melle I, Dale AM, Andreassen OA, Agartz I(2012) Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis Am J Med Genet B Neuropsychiatr Genet, 159B(6), 722-30 DOI 10.1002/ajmg.b.32076, PubMed 22815203
Lindholm Carlström E, Saetre P, Rosengren A, Thygesen JH, Djurovic S, Melle I, Andreassen OA, Werge T, Agartz I, Hall H, Terenius L, Jönsson EG(2012) Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia Behav Brain Funct, 8, 24 DOI 10.1186/1744-9081-8-24, PubMed 22594806
Mattingsdal M, Brown AA, Djurovic S, Sønderby IE, Server A, Melle I, Agartz I, Hovig E, Jensen J, Andreassen OA(2012) Pathway analysis of genetic markers associated with a functional MRI faces paradigm implicates polymorphisms in calcium responsive pathways Neuroimage, 70, 143-9 DOI 10.1016/j.neuroimage.2012.12.035, PubMed 23274185
Mellerup E, Andreassen O, Bennike B, Dam H, Djurovic S, Hansen T, Melle I, Møller GL, Mors O, Koefoed P(2012) Connection between genetic and clinical data in bipolar disorder PLoS One, 7(9), e44623 DOI 10.1371/journal.pone.0044623, PubMed 23028568
Ousdal OT, Anand Brown A, Jensen J, Nakstad PH, Melle I, Agartz I, Djurovic S, Bogdan R, Hariri AR, Andreassen OA(2012) Associations between variants near a monoaminergic pathways gene (PHOX2B) and amygdala reactivity: a genome-wide functional imaging study Twin Res Hum Genet, 15(3), 273-85 DOI 10.1017/thg.2012.5, PubMed 22856363
Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KSet al.(2012) Identification of common variants associated with human hippocampal and intracranial volumes Nat Genet, 44(5), 552-61 DOI 10.1038/ng.2250, PubMed 22504417
Steinberg S, de Jong S, Mattheisen M, Costas J, Demontis D, Jamain S, Pietiläinen OP, Lin K, Papiol S, Huttenlocher J, Sigurdsson E, Vassos E, Giegling I, Breuer R, Fraser G, Walker N, Melle I, Djurovic S, Agartz I, Tuulio-Henriksson A, Suvisaari J, Lönnqvist J, Paunio T, Olsen L, Hansen Tet al.(2012) Common variant at 16p11.2 conferring risk of psychosis Mol Psychiatry, 19(1), 108-14 DOI 10.1038/mp.2012.157, PubMed 23164818
Vassos E, Steinberg S, Cichon S, Breen G, Sigurdsson E, Andreassen OA, Djurovic S, Morken G, Grigoroiu-Serbanescu M, Diaconu CC, Czerski PM, Hauser J, Babadjanova G, Abramova LI, Mühleisen TW, Nöthen MM, Rietschel M, McGuffin P, St Clair D, Gustafsson O, Melle I, Pietiläinen OP, Ruggeri M, Tosato S, Werge Tet al.(2012) Replication study and meta-analysis in European samples supports association of the 3p21.1 locus with bipolar disorder Biol Psychiatry, 72(8), 645-50 DOI 10.1016/j.biopsych.2012.02.040, PubMed 22560537
Wirgenes KV, Sønderby IE, Haukvik UK, Mattingsdal M, Tesli M, Athanasiu L, Sundet K, Røssberg JI, Dale AM, Brown AA, Agartz I, Melle I, Djurovic S, Andreassen OA(2012) TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders Transl Psychiatry, 2(5), e112 DOI 10.1038/tp.2012.39, PubMed 22832956
Publications 2011
Agartz I, Brown AA, Rimol LM, Hartberg CB, Dale AM, Melle I, Djurovic S, Andreassen OA(2011) Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia Biol Psychiatry, 70(7), 696-8 DOI 10.1016/j.biopsych.2011.02.034, PubMed 21514568
Bakken TE, Bloss CS, Roddey JC, Joyner AH, Rimol LM, Djurovic S, Melle I, Sundet K, Agartz I, Andreassen OA, Dale AM, Schork NJ(2011) Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia Arch Gen Psychiatry, 68(8), 781-90 DOI 10.1001/archgenpsychiatry.2011.81, PubMed 21810643
Caprini S, Saetre P, Melle I, Djurovic S, Andreassen OA, Skjødt C, Duong L, Werge T, Hall H, Agartz I, Terenius L, Jönsson EG(2011) Lack of association between two dopamine D2 receptor gene polymorphisms and schizophrenia Psychiatr Genet, 21(4), 214-5 DOI 10.1097/YPG.0b013e328341e020, PubMed 21712758
Cichon S, Muehleisen TW, Degenhardt FA, Mattheisen M, Miro X, Strohmaier J, Steffens M, Meesters C, Herms S, Weingarten M, Priebe L, Haenisch B, Alexander M, Vollmer J, Breuer R, Schmal C, Tessmann P, Moebus S, Wichmann HE, Schreiber S, Muller-Myhsok B, Lucae S, Jamain S, Leboyer M, Bellivier Fet al.(2011) Genome-wide Association Study Identifies Genetic Variation in Neurocan as a Susceptibility Factor for Bipolar Disorder (vol 88, pg 372, 2011) Am. J. Hum. Genet., 88(3), 396 DOI 10.1016/j.ajhg.2011.03.001
Cichon S, Mühleisen TW, Degenhardt FA, Mattheisen M, Miró X, Strohmaier J, Steffens M, Meesters C, Herms S, Weingarten M, Priebe L, Haenisch B, Alexander M, Vollmer J, Breuer R, Schmäl C, Tessmann P, Moebus S, Wichmann HE, Schreiber S, Müller-Myhsok B, Lucae S, Jamain S, Leboyer M, Bellivier Fet al.(2011) Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder Am J Hum Genet, 88(3), 372-81 DOI 10.1016/j.ajhg.2011.01.017, PubMed 21353194
Finsen AV, Lunde IG, Sjaastad I, Østli EK, Lyngra M, Jarstadmarken HO, Hasic A, Nygård S, Wilcox-Adelman SA, Goetinck PF, Lyberg T, Skrbic B, Florholmen G, Tønnessen T, Louch WE, Djurovic S, Carlson CR, Christensen G(2011) Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway PLoS One, 6(12), e28302 DOI 10.1371/journal.pone.0028302, PubMed 22164265
Hansen T, Ingason A, Djurovic S, Melle I, Fenger M, Gustafsson O, Jakobsen KD, Rasmussen HB, Tosato S, Rietschel M, Frank J, Owen M, Bonetto C, Suvisaari J, Thygesen JH, Pétursson H, Lönnqvist J, Sigurdsson E, Giegling I, Craddock N, O'Donovan MC, Ruggeri M, Cichon S, Ophoff RA, Pietiläinen Oet al.(2011) At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia Biol Psychiatry, 70(1), 59-63 DOI 10.1016/j.biopsych.2011.01.031, PubMed 21414605
Håvik B, Le Hellard S, Rietschel M, Lybæk H, Djurovic S, Mattheisen M, Mühleisen TW, Degenhardt F, Priebe L, Maier W, Breuer R, Schulze TG, Agartz I, Melle I, Hansen T, Bramham CR, Nöthen MM, Stevens B, Werge T, Andreassen OA, Cichon S, Steen VM(2011) The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia Biol Psychiatry, 70(1), 35-42 DOI 10.1016/j.biopsych.2011.01.030, PubMed 21439553
Ingason A, Kirov G, Giegling I, Hansen T, Isles AR, Jakobsen KD, Kristinsson KT, le Roux L, Gustafsson O, Craddock N, Möller HJ, McQuillin A, Muglia P, Cichon S, Rietschel M, Ophoff RA, Djurovic S, Andreassen OA, Pietiläinen OP, Peltonen L, Dempster E, Collier DA, St Clair D, Rasmussen HB, Glenthøj BYet al.(2011) Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness Am J Psychiatry, 168(4), 408-17 DOI 10.1176/appi.ajp.2010.09111660, PubMed 21324950
Koefoed P, Andreassen OA, Bennike B, Dam H, Djurovic S, Hansen T, Jorgensen MB, Kessing LV, Melle I, Møller GL, Mors O, Werge T, Mellerup E(2011) Combinations of SNPs related to signal transduction in bipolar disorder PLoS One, 6(8), e23812 DOI 10.1371/journal.pone.0023812, PubMed 21897858
LeBlanc M, Kulle B, Sundet K, Agartz I, Melle I, Djurovic S, Frigessi A, Andreassen OA(2011) Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function J Psychiatr Res, 46(2), 271-8 DOI 10.1016/j.jpsychires.2011.11.001, PubMed 22126837
Olsen L, Hansen T, Djurovic S, Haastrup E, Albrecthsen A, Hoeffding LK, Secher A, Gustafsson O, Jakobsen KD, Nielsen FC, Ullum H, Morken G, Agartz I, Melle I, Gether U, Andreassen OA, Werge T(2011) Copy number variations in affective disorders and meta-analysis Psychiatr Genet, 21(6), 319-22 DOI 10.1097/YPG.0b013e3283463deb, PubMed 21451435
Pers TH, Hansen NT, Lage K, Koefoed P, Dworzynski P, Miller ML, Flint TJ, Mellerup E, Dam H, Andreassen OA, Djurovic S, Melle I, Børglum AD, Werge T, Purcell S, Ferreira MA, Kouskoumvekaki I, Workman CT, Hansen T, Mors O, Brunak S(2011) Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes Genet Epidemiol, 35(5), 318-32 DOI 10.1002/gepi.20580, PubMed 21484861
Steinberg S, de Jong S, Irish Schizophrenia Genomics Consortium, Andreassen OA, Werge T, Børglum AD, Mors O, Mortensen PB, Gustafsson O, Costas J, Pietiläinen OP, Demontis D, Papiol S, Huttenlocher J, Mattheisen M, Breuer R, Vassos E, Giegling I, Fraser G, Walker N, Tuulio-Henriksson A, Suvisaari J, Lönnqvist J, Paunio T, Agartz Iet al.(2011) Common variants at VRK2 and TCF4 conferring risk of schizophrenia Hum Mol Genet, 20(20), 4076-81 DOI 10.1093/hmg/ddr325, PubMed 21791550
Tesli M, Koefoed P, Athanasiu L, Mattingsdal M, Gustafsson O, Agartz I, Rimol LM, Brown A, Wirgenes KV, Smorr LL, Kähler AK, Werge T, Mors O, Mellerup E, Jönsson EG, Melle I, Morken G, Djurovic S, Andreassen OA(2011) Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples Am J Med Genet B Neuropsychiatr Genet, 156B(8), 969-74 DOI 10.1002/ajmg.b.31244, PubMed 21972176
Van Schijndel JE, Van Zweeden M, Van Loo KM, Djurovic S, Andreassen OA, Hansen T, Werge T, Nyegaard M, Sørensen KM, Nordentoft M, Mortensen PB, Mors O, Børglum AD, Del-Favero J, Norrback KF, Adolfsson R, De Hert M, Claes S, Cichon S, Rietschel M, Nöthen MM, Kallunki P, Pedersen JT, Martens GJ(2011) Dual association of a TRKA polymorphism with schizophrenia Psychiatr Genet, 21(3), 125-31 DOI 10.1097/YPG.0b013e3283437194, PubMed 21317683
Aas M, Djurovic S, Athanasiu L, Steen NE, Agartz I, Lorentzen S, Sundet K, Andreassen OA, Melle I(2011) Serotonin transporter gene polymorphism, childhood trauma, and cognition in patients with psychotic disorders Schizophr Bull, 38(1), 15-22 DOI 10.1093/schbul/sbr113, PubMed 21908796
Publications 2010
Athanasiu L, Mattingsdal M, Kähler AK, Brown A, Gustafsson O, Agartz I, Giegling I, Muglia P, Cichon S, Rietschel M, Pietiläinen OP, Peltonen L, Bramon E, Collier D, Clair DS, Sigurdsson E, Petursson H, Rujescu D, Melle I, Steen VM, Djurovic S, Andreassen OA(2010) Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort J Psychiatr Res, 44(12), 748-53 DOI 10.1016/j.jpsychires.2010.02.002, PubMed 20185149
Athanasiu L, Mattingsdal M, Melle I, Inderhaug E, Lien T, Agartz I, Lorentzen S, Morken G, Andreassen OA, Djurovic S(2010) Intron 12 in NTRK3 is associated with bipolar disorder Psychiatry Res, 185(3), 358-62 DOI 10.1016/j.psychres.2010.05.011, PubMed 20554328
Chen X, Lee G, Maher BS, Fanous AH, Chen J, Zhao Z, Guo A, van den Oord E, Sullivan PF, Shi J, Levinson DF, Gejman PV, Sanders A, Duan J, Owen MJ, Craddock NJ, O'Donovan MC, Blackman J, Lewis D, Kirov GK, Qin W, Schwab S, Wildenauer D, Chowdari K, Nimgaonkar Vet al.(2010) GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia Mol Psychiatry, 16(11), 1117-29 DOI 10.1038/mp.2010.96, PubMed 20838396
Djurovic S, Gustafsson O, Mattingsdal M, Athanasiu L, Bjella T, Tesli M, Agartz I, Lorentzen S, Melle I, Morken G, Andreassen OA(2010) A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample J Affect Disord, 126(1-2), 312-6 DOI 10.1016/j.jad.2010.04.007, PubMed 20451256
Holtze M, Saetre P, Erhardt S, Schwieler L, Werge T, Hansen T, Nielsen J, Djurovic S, Melle I, Andreassen OA, Hall H, Terenius L, Agartz I, Engberg G, Jönsson EG, Schalling M(2010) Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: an association study Schizophr Res, 127(1-3), 270-2 DOI 10.1016/j.schres.2010.10.002, PubMed 21030213
Hope S, Melle I, Aukrust P, Agartz I, Lorentzen S, Steen NE, Djurovic S, Ueland T, Andreassen OA(2010) Osteoprotegerin levels in patients with severe mental disorders J Psychiatry Neurosci, 35(5), 304-10 DOI 10.1503/jpn.090088, PubMed 20569643
Ingason A, Giegling I, Cichon S, Hansen T, Rasmussen HB, Nielsen J, Jürgens G, Muglia P, Hartmann AM, Strengman E, Vasilescu C, Mühleisen TW, Djurovic S, Melle I, Lerer B, Möller HJ, Francks C, Pietiläinen OP, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Walshe M, Vassos E, Di Forti M, Murray Ret al.(2010) A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia Hum Mol Genet, 19(7), 1379-86 DOI 10.1093/hmg/ddq009, PubMed 20071346
Kähler AK, Djurovic S, Rimol LM, Brown AA, Athanasiu L, Jönsson EG, Hansen T, Gústafsson O, Hall H, Giegling I, Muglia P, Cichon S, Rietschel M, Pietiläinen OP, Peltonen L, Bramon E, Collier D, St Clair D, Sigurdsson E, Petursson H, Rujescu D, Melle I, Werge T, Steen VM, Dale AMet al.(2010) Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area Biol Psychiatry, 69(1), 90-6 DOI 10.1016/j.biopsych.2010.07.035, PubMed 20950796
Kähler AK, Otnaess MK, Wirgenes KV, Hansen T, Jönsson EG, Agartz I, Hall H, Werge T, Morken G, Mors O, Mellerup E, Dam H, Koefod P, Melle I, Steen VM, Andreassen OA, Djurovic S(2010) Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples Am J Med Genet B Neuropsychiatr Genet, 153B(1), 86-96 DOI 10.1002/ajmg.b.30958, PubMed 19350560
Saetre P, Lundmark P, Wang A, Hansen T, Rasmussen HB, Djurovic S, Melle I, Andreassen OA, Werge T, Agartz I, Hall H, Terenius L, Jönsson EG(2010) The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis Am J Med Genet B Neuropsychiatr Genet, 153B(2), 387-396 DOI 10.1002/ajmg.b.30991, PubMed 19526457
Steen NE, Tesli M, Kähler AK, Methlie P, Hope S, Barrett EA, Larsson S, Mork E, Løvås K, Røssberg JI, Agartz I, Melle I, Djurovic S, Lorentzen S, Berg JP, Andreassen OA(2010) SRD5A2 is associated with increased cortisol metabolism in schizophrenia spectrum disorders Prog Neuropsychopharmacol Biol Psychiatry, 34(8), 1500-6 DOI 10.1016/j.pnpbp.2010.08.013, PubMed 20800085
Steinberg S, Mors O, Børglum AD, Gustafsson O, Werge T, Mortensen PB, Andreassen OA, Sigurdsson E, Thorgeirsson TE, Böttcher Y, Olason P, Ophoff RA, Cichon S, Gudjonsdottir IH, Pietiläinen OP, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Athanasiu L, Suvisaari J, Lonnqvist J, Paunio T, Hartmann A, Jürgens Get al.(2010) Expanding the range of ZNF804A variants conferring risk of psychosis Mol Psychiatry, 16(1), 59-66 DOI 10.1038/mp.2009.149, PubMed 20048749
Tesli M, Athanasiu L, Mattingsdal M, Kähler AK, Gustafsson O, Andreassen BK, Werge T, Hansen T, Mors O, Mellerup E, Koefoed P, Jönsson EG, Agartz I, Melle I, Morken G, Djurovic S, Andreassen OA(2010) Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample Am J Med Genet B Neuropsychiatr Genet, 153B(7), 1276-82 DOI 10.1002/ajmg.b.31098, PubMed 20872766
Vares M, Saetre P, Deng H, Cai G, Liu X, Hansen T, Rasmussen HB, Werge T, Melle I, Djurovic S, Andreassen OA, Agartz I, Hall H, Terenius L, Jönsson EG(2010) Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia Am J Med Genet B Neuropsychiatr Genet, 153B(2), 610-618 DOI 10.1002/ajmg.b.31030, PubMed 19746410
Wirgenes KV, Djurovic S, Sundet K, Agartz I, Mattingsdal M, Athanasiu L, Melle I, Andreassen OA(2010) Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls Schizophr Res, 122(1-3), 31-7 DOI 10.1016/j.schres.2010.05.007, PubMed 20605701
Publications 2009
Andreou D, Saetre P, Lundmark P, Hansen T, Timm S, Melle I, Djurovic S, Andreassen OA, Werge T, Hall H, Agartz I, Terenius L, Jönsson EG(2009) Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia Psychiatr Genet, 19(5), 273-4 DOI 10.1097/YPG.0b013e32832a4fcd, PubMed 19491717
Djurović S, Cirisan M, Demura AV, Demchenko GV, Nikolić D, Gigosos MA, González MA(2009) Measurements of Hbeta Stark central asymmetry and its analysis through standard theory and computer simulations Phys Rev E Stat Nonlin Soft Matter Phys, 79(4 Pt 2), 046402 DOI 10.1103/PhysRevE.79.046402, PubMed 19518354
Djurovic S, Le Hellard S, Kähler AK, Jönsson EG, Agartz I, Steen VM, Hall H, Wang AG, Rasmussen HB, Melle I, Werge T, Andreassen OA(2009) Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE) Psychiatry Res, 168(3), 256-8 DOI 10.1016/j.psychres.2008.08.007, PubMed 19223264
Ingason A, Rujescu D, Cichon S, Sigurdsson E, Sigmundsson T, Pietiläinen OP, Buizer-Voskamp JE, Strengman E, Francks C, Muglia P, Gylfason A, Gustafsson O, Olason PI, Steinberg S, Hansen T, Jakobsen KD, Rasmussen HB, Giegling I, Möller HJ, Hartmann A, Crombie C, Fraser G, Walker N, Lonnqvist J, Suvisaari Jet al.(2009) Copy number variations of chromosome 16p13.1 region associated with schizophrenia Mol Psychiatry, 16(1), 17-25 DOI 10.1038/mp.2009.101, PubMed 19786961
Joyner AH, J CR, Bloss CS, Bakken TE, Rimol LM, Melle I, Agartz I, Djurovic S, Topol EJ, Schork NJ, Andreassen OA, Dale AM(2009) A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations Proc Natl Acad Sci U S A, 106(36), 15483-8 DOI 10.1073/pnas.0901866106, PubMed 19717458
Jönsson EG, Saetre P, Vares M, Andreou D, Larsson K, Timm S, Rasmussen HB, Djurovic S, Melle I, Andreassen OA, Agartz I, Werge T, Hall H, Terenius L(2009) DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study Neuropsychobiology, 59(3), 142-50 DOI 10.1159/000218076, PubMed 19439994
Otnaess MK, Djurovic S, Rimol LM, Kulle B, Kähler AK, Jönsson EG, Agartz I, Sundet K, Hall H, Timm S, Hansen T, Callicott JH, Melle I, Werge T, Andreassen OA(2009) Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia Neurobiol Dis, 34(3), 518-24 DOI 10.1016/j.nbd.2009.03.011, PubMed 19344762
Rimol LM, Agartz I, Djurovic S, Brown AA, Roddey JC, Kähler AK, Mattingsdal M, Athanasiu L, Joyner AH, Schork NJ, Halgren E, Sundet K, Melle I, Dale AM, Andreassen OA, Alzheimer's Disease Neuroimaging Initiative(2009) Sex-dependent association of common variants of microcephaly genes with brain structure Proc Natl Acad Sci U S A, 107(1), 384-8 DOI 10.1073/pnas.0908454107, PubMed 20080800
Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietiläinen OP, Mors O, Mortensen PB, Sigurdsson E, Gustafsson O, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Suvisaari J, Lonnqvist J, Paunio T, Børglum AD, Hartmann A, Fink-Jensen A, Nordentoft M, Hougaard D, Norgaard-Pedersen Bet al.(2009) Common variants conferring risk of schizophrenia Nature, 460(7256), 744-7 DOI 10.1038/nature08186, PubMed 19571808
Tesli M, Kähler AK, Andreassen BK, Werge T, Mors O, Mellerup E, Koefoed P, Melle I, Morken G, Wirgenes KV, Andreassen OA, Djurovic S(2009) No association between DGKH and bipolar disorder in a Scandinavian case-control sample Psychiatr Genet, 19(5), 269-72 DOI 10.1097/YPG.0b013e32832d302f, PubMed 19478689
van Schijndel JE, van Loo KM, van Zweeden M, Djurovic S, Andreassen OA, Hansen T, Werge T, Kallunki P, Pedersen JT, Martens GJ(2009) Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia J Psychiatr Res, 43(15), 1195-9 DOI 10.1016/j.jpsychires.2009.04.006, PubMed 19435634
Wirgenes KV, Djurovic S, Agartz I, Jonsson EG, Werge T, Melle I, Andreassen OA(2009) Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia Neuropsychobiology, 60(1), 31-6 DOI 10.1159/000235799, PubMed 19729970
Publications 2008
Djurovic S, Kähler AK, Kulle B, Jönsson EG, Agartz I, Le Hellard S, Hall H, Jakobsen KD, Hansen T, Melle I, Werge T, Steen VM, Andreassen OA(2008) A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE) Schizophr Res, 107(2-3), 242-8 DOI 10.1016/j.schres.2008.10.010, PubMed 19022628
Jönsson EG, Larsson K, Vares M, Hansen T, Wang AG, Djurovic S, Rønningen KS, Andreassen OA, Agartz I, Werge T, Terenius L, Hall H(2008) Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study Am J Med Genet B Neuropsychiatr Genet, 147B(6), 976-82 DOI 10.1002/ajmg.b.30671, PubMed 18165967
Kähler AK, Djurovic S, Kulle B, Jönsson EG, Agartz I, Hall H, Opjordsmoen S, Jakobsen KD, Hansen T, Melle I, Werge T, Steen VM, Andreassen OA(2008) Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene Am J Med Genet B Neuropsychiatr Genet, 147B(7), 1089-100 DOI 10.1002/ajmg.b.30726, PubMed 18384059
Le Hellard S, Mühleisen TW, Djurovic S, Fernø J, Ouriaghi Z, Mattheisen M, Vasilescu C, Raeder MB, Hansen T, Strohmaier J, Georgi A, Brockschmidt FF, Melle I, Nenadic I, Sauer H, Rietschel M, Nöthen MM, Werge T, Andreassen OA, Cichon S, Steen VM(2008) Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples Mol Psychiatry, 15(5), 463-72 DOI 10.1038/mp.2008.110, PubMed 18936756
Olsen L, Hansen T, Jakobsen KD, Djurovic S, Melle I, Agartz I, Hall H, Ullum H, Timm S, Wang AG, Jönsson EG, Andreassen OA, Werge T(2008) The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples BMC Med Genet, 9, 39 DOI 10.1186/1471-2350-9-39, PubMed 18460190
Rujescu D, Ingason A, Cichon S, Pietiläinen OP, Barnes MR, Toulopoulou T, Picchioni M, Vassos E, Ettinger U, Bramon E, Murray R, Ruggeri M, Tosato S, Bonetto C, Steinberg S, Sigurdsson E, Sigmundsson T, Petursson H, Gylfason A, Olason PI, Hardarsson G, Jonsdottir GA, Gustafsson O, Fossdal R, Giegling Iet al.(2008) Disruption of the neurexin 1 gene is associated with schizophrenia Hum Mol Genet, 18(5), 988-96 DOI 10.1093/hmg/ddn351, PubMed 18945720
Saetre P, Agartz I, De Franciscis A, Lundmark P, Djurovic S, Kähler A, Andreassen OA, Jakobsen KD, Rasmussen HB, Werge T, Hall H, Terenius L, Jönsson EG(2008) Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample Schizophr Res, 106(2-3), 237-41 DOI 10.1016/j.schres.2008.08.024, PubMed 18818052
Stefansson H, Rujescu D, Cichon S, Pietiläinen OP, Ingason A, Steinberg S, Fossdal R, Sigurdsson E, Sigmundsson T, Buizer-Voskamp JE, Hansen T, Jakobsen KD, Muglia P, Francks C, Matthews PM, Gylfason A, Halldorsson BV, Gudbjartsson D, Thorgeirsson TE, Sigurdsson A, Jonasdottir A, Jonasdottir A, Bjornsson A, Mattiasdottir S, Blondal Tet al.(2008) Large recurrent microdeletions associated with schizophrenia Nature, 455(7210), 232-6 DOI 10.1038/nature07229, PubMed 18668039
Publications 2007
Djurovic S, Berge KE, Birkenes B, Braaten Ø, Retterstøl L(2007) The effect of red wine on plasma leptin levels and vasoactive factors from adipose tissue: a randomized crossover trial Alcohol Alcohol, 42(6), 525-8 DOI 10.1093/alcalc/agm056, PubMed 17670801
Hansen T, Olsen L, Lindow M, Jakobsen KD, Ullum H, Jonsson E, Andreassen OA, Djurovic S, Melle I, Agartz I, Hall H, Timm S, Wang AG, Werge T(2007) Brain expressed microRNAs implicated in schizophrenia etiology PLoS One, 2(9), e873 DOI 10.1371/journal.pone.0000873, PubMed 17849003
Zacchigna S, Østli EK, Arsic N, Pattarini L, Giacca M, Djurovic S(2007) A novel myogenic cell line with phenotypic properties of muscle progenitors J Mol Med (Berl), 86(1), 105-15 DOI 10.1007/s00109-007-0268-0, PubMed 17957349
Publications 2006
Pasalic D, Bilic-Zulle L, Stimac D, Krznaric Z, Ferencak G, Grskovic B, Djurovic S, Stavljenic-Rukavina A(2006) Influence of different lipoprotein lipase gene polymorphisms on developing pancreatitis of different etiology in Croatian patients Period. Biol., 108(5), 581-586
Publications 2005
Djurović S, Nikolić D, Savić I, Sörge S, Demura AV(2005) Asymmetry of Hbeta Stark profiles in T-tube hydrogen plasma Phys Rev E Stat Nonlin Soft Matter Phys, 71(3 Pt 2B), 036407 DOI 10.1103/PhysRevE.71.036407, PubMed 15903588
Eliassen KA, Brodal BP, Svindland A, Osmundsen H, Rønning H, Djurovic S, Berg K(2005) Activity of peroxisomal enzymes, and levels of polyamines in LPA-transgenic mice on two different diets Lipids Health Dis, 4, 23 DOI 10.1186/1476-511X-4-23, PubMed 16202171
Iversen N, Birkenes B, Torsdalen K, Djurovic S(2005) Electroporation by nucleofector is the best nonviral transfection technique in human endothelial and smooth muscle cells Genet Vaccines Ther, 3(1), 2 DOI 10.1186/1479-0556-3-2, PubMed 15836781
Stanojević NB, Ivanović ZJ, Djurovic S, Kalimanovska VS, Spasić S, Ostrić DK, Memon L(2005) Lack of association between low HDL-cholesterol and elevated circulating cellular adhesion molecules in normolipidemic CAD patients and healthy subjects Int Heart J, 46(4), 593-600 DOI 10.1536/ihj.46.593, PubMed 16157950
Woldbaek PR, Sande JB, Strømme TA, Lunde PK, Djurovic S, Lyberg T, Christensen G, Tønnessen T(2005) Daily administration of interleukin-18 causes myocardial dysfunction in healthy mice Am J Physiol Heart Circ Physiol, 289(2), H708-14 DOI 10.1152/ajpheart.01179.2004, PubMed 15821032
Publications 2004
Djurovic S, Iversen N, Jeansson S, Hoover F, Christensen G(2004) Comparison of nonviral transfection and adeno-associated viral transduction on cardiomyocytes Mol Biotechnol, 28(1), 21-32 DOI 10.1385/MB:28:1:21, PubMed 15456960
Djurovic S, Kristansen H, Sletten M, Halvorsen K, Berg K(2004) Variations in transfection efficiency of VEGF165 and VEGF121-cDNA: its effects on proliferation and migration of human endothelial cells Mol Biotechnol, 26(1), 7-16 DOI 10.1385/MB:26:1:7, PubMed 14734819
Pasalić D, Jurcić Z, Stipancić G, Ferencak G, Leren TP, Djurovic S, Stavljenić-Rukavina A(2004) Missense mutation W86R in exon 3 of the lipoprotein lipase gene in a boy with chylomicronemia Clin Chim Acta, 343(1-2), 179-84 DOI 10.1016/j.cccn.2004.01.029, PubMed 15115692
Teivainen PA, Eliassen KA, Rubin EM, Djurovic S, Berg K(2004) Human apoB contributes to increased serum total apo(a) level in LPA transgenic mice Lipids Health Dis, 3, 8 DOI 10.1186/1476-511X-3-8, PubMed 15134578
Publications 2003
Bogavac-Stanojevic N, Djurovic S, Jelic-Ivanovic Z, Spasojevic-Kalimanovska V, Kalimanovska-Ostric D(2003) Circulating transforming growth factor-beta1, lipoprotein(a) and cellular adhesion molecules in angiographically assessed coronary artery disease Clin Chem Lab Med, 41(7), 893-8 DOI 10.1515/CCLM.2003.135, PubMed 12940514
Nikolić D, Djurović S, Mijatović Z, Kobilarov R(2003) Comment on "Atomic spectral line-free parameter deconvolution procedure" Phys Rev E Stat Nonlin Soft Matter Phys, 67(5 Pt 2), 058401; author reply 058402 DOI 10.1103/PhysRevE.67.058401, PubMed 12786332
Os I, Høieggen A, Larsen A, Sandset PM, Djurovic S, Berg K, Os A, Birkeland K, Westheim A(2003) Smoking and relation to other risk factors in postmenopausal women with coronary artery disease, with particular reference to whole blood viscosity and beta-cell function J Intern Med, 253(2), 232-9 DOI 10.1046/j.1365-2796.2003.01110.x, PubMed 12542565
Publications 2002
Berg K, Svindland A, Smith AJ, Lawn RM, Djurovic S, Aleström A, Aleström P, Eliassen K(2002) Spontaneous atherosclerosis in the proximal aorta of LPA transgenic mice on a normal diet Atherosclerosis, 163(1), 99-104 DOI 10.1016/s0021-9150(01)00772-9, PubMed 12048126
Clausen T, Djurovic S, Reseland JE, Berg K, Drevon CA, Henriksen T(2002) Altered plasma concentrations of leptin, transforming growth factor-beta(1) and plasminogen activator inhibitor type 2 at 18 weeks of gestation in women destined to develop pre-eclampsia. Circulating markers of disturbed placentation? Placenta, 23(5), 380-5 DOI 10.1053/plac.2002.0828, PubMed 12061853
Djurovic S, Clausen T, Wergeland R, Brosstad F, Berg K, Henriksen T(2002) Absence of enhanced systemic inflammatory response at 18 weeks of gestation in women with subsequent pre-eclampsia BJOG, 109(7), 759-64 DOI 10.1111/j.1471-0528.2002.01330.x, PubMed 12135211
Os I, Djurovic S, Seljeflot I, Berg K(2002) Transforming growth factor (TGF)-beta1 inversely related to vascular cell adhesion molecule-1 in postmenopausal women with coronary artery disease. A possible mechanism for the putative cardioprotective role of TGF-beta1? J Intern Med, 251(3), 223-7 DOI 10.1046/j.1365-2796.2002.00950.x, PubMed 11886481
Os I, Os A, Sandset PM, Bølling S, Seljeflot I, Djurovic S, Westheim A(2002) Hormone replacement therapy does not affect plasma homocysteine in postmenopausal women with coronary artery disease. Free tissue factor pathway inhibitor antigen, a circulating anticoagulant, is related to plasma homocysteine Cardiology, 98(1-2), 6-12 DOI 10.1159/000064667, PubMed 12373040
Publications 2001
Clausen T, Djurovic S, Henriksen T(2001) Dyslipidemia in early second trimester is mainly a feature of women with early onset pre-eclampsia BJOG, 108(10), 1081-7 DOI 10.1111/j.1471-0528.2001.00247.x, PubMed 11702841
Retterstol L, Djurovic S, Bohn M, Bakken A, Erikssen J, Berg K(2001) Plasma N-terminal pro-atrial natriuretic peptide predicts death after premature myocardial infarction, but not as well as radionuclide ejection fraction. A ten-year follow-up study Scand Cardiovasc J, 35(6), 373-8 DOI 10.1080/14017430152754853, PubMed 11837516
Publications 2000
Berg K, Djurovic S, Rainwater DL(2000) Gene encoding the apo(a) protein in LPA Atherosclerosis, 148(1), 203 DOI 10.1016/s0021-9150(99)00348-2, PubMed 10644289
Clausen T, Djurovic S, Brosstad FR, Berg K, Henriksen T(2000) Altered circulating levels of adhesion molecules at 18 weeks' gestation among women with eventual preeclampsia: indicators of disturbed placentation in absence of evidence of endothelial dysfunction? Am J Obstet Gynecol, 182(2), 321-5 DOI 10.1016/s0002-9378(00)70218-3, PubMed 10694331
Djurovic S, Os I, Hofstad AE, Abdelnoor M, Westheim A, Berg K(2000) Increased plasma concentrations of TGF-beta1 after hormone replacement therapy J Intern Med, 247(2), 279-85 DOI 10.1046/j.1365-2796.2000.00648.x, PubMed 10692092
Svindland A, Berg K, Eliassen K, Lawn RM, Djurovic S, Aleström P, Noren T, Smith A(2000) Histopathology of arterial lesions in LPA transgenic mice on cholesterol-enriched chow Atherosclerosis, 153(2), 349-54 DOI 10.1016/s0021-9150(00)00430-5, PubMed 11164423
Szabo A, Akkouh I, Osete JR, de Assis DR, Kondratskaya E, Hughes T, Ueland T, Andreassen OA, Djurovic S(2024) NLRP3 inflammasome mediates astroglial dysregulation of innate and adaptive immune responses in schizophrenia Brain Behav Immun(in press) DOI 10.1016/j.bbi.2024.11.030, PubMed 39617069
Jaholkowski P, Bahrami S, Fominykh V, Hindley GFL, Tesfaye M, Parekh P, Parker N, Filiz TT, Nordengen K, Hagen E, Koch E, Bakken NR, Frei E, Birkenæs V, Rahman Z, Frei O, Haavik J, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Shadrin AA, Andreassen OA(2024) Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development Neurobiol Dis, 106750(in press) DOI 10.1016/j.nbd.2024.106750, PubMed 39608471
Tesfaye M, Shadrin A, Parker N, Jaholkowski P, Parekh P, Kutrolli G, Birkenæs V, Bakken NR, Ask H, Frei O, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Andreassen OA(2024) Comorbidity alters the genetic relationship between anxiety disorders and major depression medRxiv DOI 10.1101/2024.11.19.24317523, PubMed 39606413