Kevin O'Connell

  • Postdoctoral fellow; PhD
 

Publications 2022

Icick R, Shadrin A, Holen B, Karadag N, Lin A, Hindley G, O'Connell K, Frei O, Bahrami S, Høegh MC, Cheng W, Fan CC, Djurovic S, Dale AM, Lagerberg TV, Smeland OB, Andreassen OA (2022)
Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings
Neuropsychopharmacology, 47 (11), 1883-1891
DOI 10.1038/s41386-022-01401-6, PubMed 35953530

Smith RL, Wollmann BM, Kausberg M, Mæland S, Tveito M, O'Connell K, Molden E, Kringen MK (2022)
Effects of a Novel UGT2B Haplotype and UGT1A4*3 Allele Variants on Glucuronidation of Clozapine In vivo
Curr Drug Metab, 23 (1), 66-72
DOI 10.2174/1389200223666220201152953, PubMed 35105285

van der Meer D, Shadrin AA, O'Connell K, Bettella F, Djurovic S, Wolfers T, Alnæs D, Agartz I, Smeland OB, Melle I, Sánchez JM, Linden DEJ, Dale AM, Westlye LT, Andreassen OA, Frei O, Kaufmann T (2022)
Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology
Biol Psychiatry, 92 (4), 291-298
DOI 10.1016/j.biopsych.2021.12.007, PubMed 35164939

Publications 2021

Monereo-Sánchez J, Schram MT, Frei O, O'Connell K, Shadrin AA, Smeland OB, Westlye LT, Andreassen OA, Kaufmann T, Linden DEJ, van der Meer D (2021)
Genetic Overlap Between Alzheimer's Disease and Depression Mapped Onto the Brain
Front Neurosci, 15, 653130
DOI 10.3389/fnins.2021.653130, PubMed 34290577

Publications 2020

Bahrami S, Steen NE, Shadrin A, O'Connell K, Frei O, Bettella F, Wirgenes KV, Krull F, Fan CC, Dale AM, Smeland OB, Djurovic S, Andreassen OA (2020)
Shared Genetic Loci Between Body Mass Index and Major Psychiatric Disorders: A Genome-wide Association Study
JAMA Psychiatry, 77 (5), 503-512
DOI 10.1001/jamapsychiatry.2019.4188, PubMed 31913414

Caddy SL, Vaysburd M, Papa G, Wing M, O'Connell K, Stoycheva D, Foss S, Terje Andersen J, Oxenius A, James LC (2020)
Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity
EMBO J, 40 (5), e106228
DOI 10.15252/embj.2020106228, PubMed 33258165

Caddy SL, Vaysburd M, Wing M, Foss S, Andersen JT, O'Connell K, Mayes K, Higginson K, Iturriza-Gómara M, Desselberger U, James LC (2020)
Intracellular neutralisation of rotavirus by VP6-specific IgG
PLoS Pathog, 16 (8), e1008732
DOI 10.1371/journal.ppat.1008732, PubMed 32750093

Smeland OB, Bahrami S, Frei O, Shadrin A, O'Connell K, Savage J, Watanabe K, Krull F, Bettella F, Steen NE, Ueland T, Posthuma D, Djurovic S, Dale AM, Andreassen OA (2020)
Correction: Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
Mol Psychiatry, 25 (4), 914
DOI 10.1038/s41380-019-0456-7, PubMed 31308466

Smith RL, O'Connell K, Athanasiu L, Djurovic S, Kringen MK, Andreassen OA, Molden E (2020)
Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits
Transl Psychiatry, 10 (1), 198
DOI 10.1038/s41398-020-00888-1, PubMed 32555152

Smith RL, O'Connell K, Athanasiu L, Djurovic S, Kringen MK, Andreassen OA, Molden E (2020)
Correction: Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits
Transl Psychiatry, 10 (1), 366
DOI 10.1038/s41398-020-01061-4, PubMed 33139722

Publications 2019

Bottermann M, Foss S, Caddy SL, Clift D, van Tienen LM, Vaysburd M, Cruickshank J, O'Connell K, Clark J, Mayes K, Higginson K, Lode HE, McAdam MB, Sandlie I, Andersen JT, James LC (2019)
Complement C4 Prevents Viral Infection through Capsid Inactivation
Cell Host Microbe, 25 (4), 617-629.e7
DOI 10.1016/j.chom.2019.02.016, PubMed 30926239

Smeland OB, Bahrami S, Frei O, Shadrin A, O'Connell K, Savage J, Watanabe K, Krull F, Bettella F, Steen NE, Ueland T, Posthuma D, Djurovic S, Dale AM, Andreassen OA (2019)
Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
Mol Psychiatry, 25 (4), 844-853
DOI 10.1038/s41380-018-0332-x, PubMed 30610197

Smeland OB, Frei O, Shadrin A, O'Connell K, Fan CC, Bahrami S, Holland D, Djurovic S, Thompson WK, Dale AM, Andreassen OA (2019)
Discovery of shared genomic loci using the conditional false discovery rate approach
Hum Genet, 139 (1), 85-94
DOI 10.1007/s00439-019-02060-2, PubMed 31520123

Publications 2018

Bottermann M, Foss S, van Tienen LM, Vaysburd M, Cruickshank J, O'Connell K, Clark J, Mayes K, Higginson K, Hirst JC, McAdam MB, Slodkowicz G, Hutchinson E, Kozik P, Andersen JT, James LC (2018)
TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination
Proc Natl Acad Sci U S A, 115 (41), 10440-10445
DOI 10.1073/pnas.1806314115, PubMed 30209217

Publications 2016

Dalvie S, Koen N, McGregor N, O'Connell K, Warnich L, Ramesar R, Nievergelt CM, Stein DJ (2016)
Toward a Global Roadmap for Precision Medicine in Psychiatry: Challenges and Opportunities
OMICS, 20 (10), 557-564
DOI 10.1089/omi.2016.0110, PubMed 27636104

Pritchett J, Mixon W, O'Connell K (2016)
Performance Improvement in 503A Compounding Pharmacies: A PLAN FOR ASSESSMENT, IMPLEMENTATION, AND SUSTAINED SUCCESS
Int J Pharm Compd, 20 (1), 29-36
PubMed 27125054

Publications 2014

O'Connell K, Knight H, Ficek K, Leonska-Duniec A, Maciejewska-Karlowska A, Sawczuk M, Stepien-Slodkowska M, O'Cuinneagain D, van der Merwe W, Posthumus M, Cieszczyk P, Collins M (2014)
Interactions between collagen gene variants and risk of anterior cruciate ligament rupture
Eur J Sport Sci, 15 (4), 341-50
DOI 10.1080/17461391.2014.936324, PubMed 25073002

Saunders CJ, Posthumus M, O'Connell K, September AV, Collins M (2014)
A variant within the AQP1 3'-untranslated region is associated with running performance, but not weight changes, during an Ironman Triathlon
J Sports Sci, 33 (13), 1342-8
DOI 10.1080/02640414.2014.989535, PubMed 25495276

Publications 2013

O'Connell K, Posthumus M, Schwellnus MP, Collins M (2013)
Collagen genes and exercise-associated muscle cramping
Clin J Sport Med, 23 (1), 64-9
DOI 10.1097/JSM.0b013e3182686aa7, PubMed 22894972

Vaysburd M, Watkinson RE, Cooper H, Reed M, O'Connell K, Smith J, Cruickshanks J, James LC (2013)
Intracellular antibody receptor TRIM21 prevents fatal viral infection
Proc Natl Acad Sci U S A, 110 (30), 12397-401
DOI 10.1073/pnas.1301918110, PubMed 23840060

Publications 2012

O'connell K, Posthumus M, Collins M (2012)
No association between COL3A1, COL6A1 or COL12A1 gene variants and range of motion
J Sports Sci, 31 (2), 181-7
DOI 10.1080/02640414.2012.723133, PubMed 23013106

Publications 2011

Boyd L, Hajjar C, O'Connell K (2011)
Time-lapse microscopy of early embryogenesis in Caenorhabditis elegans
J Vis Exp (54)
DOI 10.3791/2852, PubMed 21897352

September AV, Nell EM, O'Connell K, Cook J, Handley CJ, van der Merwe L, Schwellnus M, Collins M (2011)
A pathway-based approach investigating the genes encoding interleukin-1β, interleukin-6 and the interleukin-1 receptor antagonist provides new insight into the genetic susceptibility of Achilles tendinopathy
Br J Sports Med, 45 (13), 1040-7
DOI 10.1136/bjsm.2010.076760, PubMed 21558284

Publications 2008

O'Sullivan K, O'Ceallaigh B, O'Connell K, Shafat A (2008)
The relationship between previous hamstring injury and the concentric isokinetic knee muscle strength of Irish Gaelic footballers
BMC Musculoskelet Disord, 9, 30
DOI 10.1186/1471-2474-9-30, PubMed 18325107

Publications 2007

Kemp CA, Song MH, Addepalli MK, Hunter G, O'Connell K (2007)
Suppressors of zyg-1 define regulators of centrosome duplication and nuclear association in Caenorhabditis elegans
Genetics, 176 (1), 95-113
DOI 10.1534/genetics.107.071803, PubMed 17446307

Publications 2005

O'Connell K (2005)
There's no place like WormBase: an indispensable resource for Caenorhabditis elegans researchers
Biol Cell, 97 (11), 867-72
DOI 10.1042/BC20040155, PubMed 16232125

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