Akkouh IA, Osete JR, Szabo A, Andreassen OA, Djurovic S (2025)
Neurobiological Perturbations in Bipolar Disorder Compared With Schizophrenia: Evidence From Cell Cultures and Brain Organoids
98 (4), 322-332
DOI 10.1016/j.biopsych.2025.02.012, PubMed 39983953
Fominykh V, Shadrin AA, Jaholkowski P, Fuhrer J, Parker N, Wiström ED, Frei O, Smeland OB, Sanner H, Djurovic S, Andreassen OA (2025)
Mapping the genetic landscape of immune-mediated disorders: potential implications for classification and therapeutic strategies
16, 1543781
DOI 10.3389/fimmu.2025.1543781, PubMed 40406108
Höffler KD, Katrinli S, Halvorsen MW, Stavrum AK, O'Connell KS, Shadrin A, Djurovic S, Andreassen OA, Crowley JJ, Haavik J, Hagen K, Kvale G, Ressler K, Hansen B, Soares JC, Fries GR, Smith AK, Le Hellard S (2025)
Optimizing genetic ancestry adjustment in DNA methylation studies: a comparative analysis of approaches
18 (1), 69
DOI 10.1186/s13072-025-00627-0, PubMed 41088295
Icick R, Shadrin A, Holen B, Karadag N, Parker N, O'Connell KS, Frei O, Bahrami S, Høegh MC, Lagerberg TV, Cheng W, Seibert TM, Djurovic S, Dale AM, Zhou H, Edenberg HJ, Gelernter J, Smeland OB, Hindley G, Andreassen OA (2025)
Identification of risk variants and cross-disorder pleiotropy through multi-ancestry genome-wide analysis of alcohol use disorder
3 (2), 253-265
DOI 10.1038/s44220-024-00353-8, PubMed 40322774
Koch E, Shadrin AA, Parker N, Lock SK, Smith RL, Frei O, Dale AM, Djurovic S, Molden E, O Connell KS, Andreassen OA (2025)
Polygenic overlap with granulocyte counts identifies novel loci for clozapine metabolism and clozapine-induced agranulocytosis
50 (6), 947-955
DOI 10.1038/s41386-025-02054-x, PubMed 39827279
László MJ, Vigh JP, Kocsis AE, Porkoláb G, Hoyk Z, Polgár T, Walter FR, Szabó A, Djurovic S, Merkely B, Alpár A, Frecska E, Nagy Z, Deli MA, Nardai S (2025)
N,N-dimethyltryptamine mitigates experimental stroke by stabilizing the blood-brain barrier and reducing neuroinflammation
11 (33), eadx5958
DOI 10.1126/sciadv.adx5958, PubMed 40802766
O'Connell KS, Koromina M, van der Veen T, Boltz T, David FS, Yang JMK, Lin KH, Wang X, Coleman JRI, Mitchell BL, McGrouther CC, Rangan AV, Lind PA, Koch E, Harder A, Parker N, Bendl J, Adorjan K, Agerbo E, Albani D, Alemany S, Alliey-Rodriguez N, Als TD, Andlauer TFM, Antoniou A et al. (2025)
Genomics yields biological and phenotypic insights into bipolar disorder
639 (8056), 968-975
DOI 10.1038/s41586-024-08468-9, PubMed 39843750
Ormerod MBEG, Sheikh MA, Ueland T, Hjell G, Rødevand L, Sæther LS, Lunding SH, Johansen IT, Andreou D, Ueland T, Lagerberg TV, Melle I, Djurovic S, Andreassen OA, Steen NE (2025)
Minor immunomodulatory effects of psychotropics suggested in severe mental disorders: Associations of antipsychotics with beta defensin 2, antidepressants with C-reactive protein, and mood stabilizers with soluble interleukin 2 receptor
68 (1), e140
DOI 10.1192/j.eurpsy.2025.10104, PubMed 40936381
Ormerod MBEG, Ueland T, Aas M, Hjell G, Rødevand L, Sæther LS, Lunding SH, Johansen IT, Mlakar V, Andreou D, Ueland T, Lagerberg TV, Melle I, Djurovic S, Andreassen OA, Steen NE (2025)
Limited evidence of association between dysregulated immune marker levels and telomere length in severe mental disorders
37, e4
DOI 10.1017/neu.2024.62, PubMed 39844366
Shadrin AA, Hindley G, Hagen E, Parker N, Tesfaye M, Jaholkowski P, Rahman Z, Kutrolli G, Fominykh V, Djurovic S, Smeland OB, O'Connell KS, van der Meer D, Frei O, Andreassen OA, Dale AM (2025)
Distinct patterns of genetic overlap among multimorbidities revealed with trivariate MiXeR
17 (1), 106
DOI 10.1186/s13073-025-01528-3, PubMed 41023670
Strom NI, Gerring ZF, Galimberti M, Yu D, Halvorsen MW, Abdellaoui A, Rodriguez-Fontenla C, Sealock JM, Bigdeli T, Coleman JR, Mahjani B, Thorp JG, Bey K, Burton CL, Luykx JJ, Zai G, Alemany S, Andre C, Askland KD, Bäckman J, Banaj N, Barlassina C, Nissen JB, Bienvenu OJ, Black D et al. (2025)
Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder
57 (6), 1389-1401
DOI 10.1038/s41588-025-02189-z, PubMed 40360802
van der Meer D, Rahman Z, Ottas A, Parekh P, Kutrolli G, Stinson SE, Koromina M, Rokicki J, Sønderby IE, Parker N, Tesfaye M, Hindley G, Rødevand LN, Koch E, Estonian Biobank Research Team, Steen NE, Berg JP, O'Connell KS, Smeland OB, Frei O, Dale AM, Djurovic S, Lehto K, Alver M, Milani L et al. (2025)
Pleiotropic and sex-specific genetic mechanisms of circulating metabolic markers
16 (1), 4961
DOI 10.1038/s41467-025-60058-z, PubMed 40436851
Andreou D, Steen NE, Mørch-Johnsen L, Jørgensen KN, Wortinger LA, Barth C, Szabo A, O'Connell KS, Lekva T, Hjell G, Johansen IT, Ormerod MBEG, Haukvik UK, Aukrust P, Djurovic S, Yolken RH, Andreassen OA, Ueland T, Agartz I (2024)
Toxoplasma gondii infection associated with inflammasome activation and neuronal injury
14 (1), 5327
DOI 10.1038/s41598-024-55887-9, PubMed 38438515
Bahrami S, Nordengen K, Rokicki J, Shadrin AA, Rahman Z, Smeland OB, Jaholkowski PP, Parker N, Parekh P, O'Connell KS, Elvsåshagen T, Toft M, Djurovic S, Dale AM, Westlye LT, Kaufmann T, Andreassen OA (2024)
The genetic landscape of basal ganglia and implications for common brain disorders
15 (1), 8476
DOI 10.1038/s41467-024-52583-0, PubMed 39353893
Baune BT, Fromme SE, Aberg M, Adli M, Afantitis A, Akkouh I, Andreassen OA, Angulo C, Barlati S, Brasso C, Bucci P, Budde M, Buspavanich P, Cavone V, Demyttenaere K, Diaz-Caneja CM, Dierssen M, Djurovic S, Driessen M, Ebner-Priemer UW, Engelmann J, Englisch S, Fabbri C, Fossati P, Fröhlich H et al. (2024)
A stratified treatment algorithm in psychiatry: a program on stratified pharmacogenomics in severe mental illness (Psych-STRATA): concept, objectives and methodologies of a multidisciplinary project funded by Horizon Europe
275 (5), 1453-1464
DOI 10.1007/s00406-024-01944-3, PubMed 39729102
García-Marín LM, Campos AI, Diaz-Torres S, Rabinowitz JA, Ceja Z, Mitchell BL, Grasby KL, Thorp JG, Agartz I, Alhusaini S, Ames D, Amouyel P, Andreassen OA, Arfanakis K, Arias-Vasquez A, Armstrong NJ, Athanasiu L, Bastin ME, Beiser AS, Bennett DA, Bis JC, Boks MPM, Boomsma DI, Brodaty H, Brouwer RM et al. (2024)
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
56 (11), 2333-2344
DOI 10.1038/s41588-024-01951-z, PubMed 39433889
Hindley G, Drange OK, Lin A, Kutrolli G, Shadrin AA, Parker N, O'Connell KS, Rødevand L, Cheng W, Bahrami S, Karadag N, Holen B, Jaholkowski P, Woldeyohannes MT, Djurovic S, Dale AM, Frei O, Ueland T, Smeland OB, Andreassen OA (2024)
Corrigendum to "Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders" [Psychoneuroendocrinology 157 (2023) 106368]
162, 106980
DOI 10.1016/j.psyneuen.2024.106980, PubMed 38336601
Inova A, Birkenæs V, Quintana DS, Ormerod MBEG, Ueland T, Ueland T, Djurovic S, Andreassen O, Steen NE, Aas M (2024)
Cortisol and C-reactive protein (CRP) regulation in severe mental disorders
172, 107272
DOI 10.1016/j.psyneuen.2024.107272, PubMed 39740359
Ivarsdottir EV, Gudmundsson J, Tragante V, Sveinbjornsson G, Kristmundsdottir S, Stacey SN, Halldorsson GH, Magnusson MI, Oddsson A, Walters GB, Sigurdsson A, Saevarsdottir S, Beyter D, Thorleifsson G, Halldorsson BV, Melsted P, Stefansson H, Jonsdottir I, Sørensen E, Pedersen OB, Erikstrup C, Bøgsted M, Pøhl M, Røder A, Stroomberg HV et al. (2024)
Gene-based burden tests of rare germline variants identify six cancer susceptibility genes
56 (11), 2422-2433
DOI 10.1038/s41588-024-01966-6, PubMed 39472694
Jaholkowski P, Bahrami S, Fominykh V, Hindley GFL, Tesfaye M, Parekh P, Parker N, Filiz TT, Nordengen K, Hagen E, Koch E, Bakken NR, Frei E, Birkenæs V, Rahman Z, Frei O, Haavik J, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Shadrin AA, Andreassen OA (2024)
Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development
203, 106750
DOI 10.1016/j.nbd.2024.106750, PubMed 39608471
Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB (2024)
Dissecting the Shared Genetic Architecture of Common Epilepsies With Cortical Brain Morphology
10 (3), e200143
DOI 10.1212/NXG.0000000000200143, PubMed 38817246
Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Ueland T, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB (2024)
Unraveling the shared genetics of common epilepsies and general cognitive ability
122, 105-112
DOI 10.1016/j.seizure.2024.09.016, PubMed 39388989
Koch E, Kämpe A, Alver M, Sigurðarson S, Einarsson G, Partanen J, Smith RL, Jaholkowski P, Taipale H, Lähteenvuo M, Steen NE, Smeland OB, Djurovic S, Molden E, FinnGen, Estonian Biobank Research Team, Sigurdsson E, Stefánsson H, Stefánsson K, Palotie A, Milani L, O'Connell KS, Andreassen OA (2024)
Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study
49 (7), 1113-1119
DOI 10.1038/s41386-023-01792-0, PubMed 38184734
Koch E, Pardiñas AF, O'Connell KS, Selvaggi P, Camacho Collados J, Babic A, Marshall SE, Van der Eycken E, Angulo C, Lu Y, Sullivan PF, Dale AM, Molden E, Posthuma D, White N, Schubert A, Djurovic S, Heimer H, Stefánsson H, Stefánsson K, Werge T, Sønderby I, O'Donovan MC, Walters JTR, Milani L et al. (2024)
How Real-World Data Can Facilitate the Development of Precision Medicine Treatment in Psychiatry
96 (7), 543-551
DOI 10.1016/j.biopsych.2024.01.001, PubMed 38185234
Lenk HÇ, Koch E, O'Connell KS, Smith RL, Akkouh IA, Djurovic S, Andreassen OA, Molden E (2024)
Genome-wide association analysis of treatment resistant schizophrenia for variant discovery and polygenic assessment
18 (1), 108
DOI 10.1186/s40246-024-00673-x, PubMed 39334510
Mlakar V, Akkouh I, Halff EF, Srivastava DP, Birkenæs V, Ueland T, Quintana DS, Ormerod MBEG, Steen NE, Djurovic S, Andreassen OA, Aas M (2024)
Telomere biology and its maintenance in schizophrenia spectrum disorders: Exploring links to cognition
272, 89-95
DOI 10.1016/j.schres.2024.08.011, PubMed 39208769
Mäki-Marttunen T, Blackwell KT, Akkouh I, Shadrin A, Valstad M, Elvsåshagen T, Linne ML, Djurovic S, Einevoll GT, Andreassen OA (2024)
Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modeling
121 (34), e2312511121
DOI 10.1073/pnas.2312511121, PubMed 39141354
Stefansson H, Walters GB, Sveinbjornsson G, Tragante V, Einarsson G, Helgason H, Sigurðsson A, Beyter D, Snaebjarnarson AS, Ivarsdottir EV, Thorleifsson G, Halldorsson BV, Norddahl G, Styrkarsdottir U, Sturluson A, Holm H, Helgason A, Moore K, Eggertsson HP, Oddsson AH, Jonsdottir GA, Gunnarsson AF, Bjornsdottir G, Gisladottir RS, Thorgeirsson TE et al. (2024)
Homozygosity for R47H in TREM2 and the Risk of Alzheimer's Disease
390 (23), 2217-2219
DOI 10.1056/NEJMc2314334, PubMed 38899702
Szabo A, Akkouh I, Osete JR, de Assis DR, Kondratskaya E, Hughes T, Ueland T, Andreassen OA, Djurovic S (2024)
NLRP3 inflammasome mediates astroglial dysregulation of innate and adaptive immune responses in schizophrenia
124, 144-156
DOI 10.1016/j.bbi.2024.11.030, PubMed 39617069
Szabo A, O'Connell KS, Akkouh IA, Ueland T, Sønderby IE, Hope S, Røe AB, Dønnum MS, Sjaastad I, Steen NE, Ueland T, Sæther LS, Osete JR, Andreassen OA, Nærland T, Djurovic S (2024)
Elevated levels of peripheral and central nervous system immune markers reflect innate immune dysregulation in autism spectrum disorder
342, 116245
DOI 10.1016/j.psychres.2024.116245, PubMed 39481220
Sæther LS, Szabo A, Akkouh IA, Haatveit B, Mohn C, Vaskinn A, Aukrust P, Ormerod MBEG, Eiel Steen N, Melle I, Djurovic S, Andreassen OA, Ueland T, Ueland T (2024)
Cognitive and inflammatory heterogeneity in severe mental illness: Translating findings from blood to brain
118, 287-299
DOI 10.1016/j.bbi.2024.03.014, PubMed 38461955
Tesfaye M, Jaholkowski P, Shadrin AA, van der Meer D, Hindley GFL, Holen B, Parker N, Parekh P, Birkenæs V, Rahman Z, Bahrami S, Kutrolli G, Frei O, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Andreassen OA (2024)
Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders
78 (12), 783-791
DOI 10.1111/pcn.13742, PubMed 39301620
Tissink EP, Shadrin AA, van der Meer D, Parker N, Hindley G, Roelfs D, Frei O, Fan CC, Nagel M, Nærland T, Budisteanu M, Djurovic S, Westlye LT, van den Heuvel MP, Posthuma D, Kaufmann T, Dale AM, Andreassen OA (2024)
Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study
15 (1), 2655
DOI 10.1038/s41467-024-46817-4, PubMed 38531894
van der Meer D, Cheng W, Rokicki J, Fernandez-Cabello S, Shadrin A, Smeland OB, Ehrhart F, Gülöksüz S, Pries LK, Lin B, Rutten BPF, van Os J, O'Donovan M, Richards AL, Steen NE, Djurovic S, Westlye LT, Andreassen OA, Kaufmann T, Genetic Risk and Outcome of Psychosis investigators (GROUP), European Network of National Schizophrenia Networks Studying Gene-Environment Interactions Work Package 6 (EU-GEI WP6) (2024)
Clustering Schizophrenia Genes by Their Temporal Expression Patterns Aids Functional Interpretation
50 (2), 327-338
DOI 10.1093/schbul/sbad140, PubMed 37824720
Wortinger LA, Stavrum AK, Shadrin AA, Szabo A, Rukke SH, Nerland S, Smelror RE, Jørgensen KN, Barth C, Andreou D, Weibell MA, Djurovic S, Andreassen OA, Thoresen M, Ursini G, Agartz I, Le Hellard S (2024)
Divergent epigenetic responses to perinatal asphyxia in severe mental disorders
14 (1), 16
DOI 10.1038/s41398-023-02709-7, PubMed 38191519
Akkouh IA, Ueland T, Szabo A, Hughes T, Smeland OB, Andreassen OA, Osete JR, Djurovic S (2023)
Longitudinal Transcriptomic Analysis of Human Cortical Spheroids Identifies Axonal Dysregulation in the Prenatal Brain as a Mediator of Genetic Risk for Schizophrenia
95 (7), 687-698
DOI 10.1016/j.biopsych.2023.08.017, PubMed 37661009
Bang L, Bahrami S, Hindley G, Smeland OB, Rødevand L, Jaholkowski PP, Shadrin A, Connell KSO, Frei O, Lin A, Rahman Z, Cheng W, Parker N, Fan CC, Dale AM, Djurovic S, Bulik CM, Andreassen OA (2023)
Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia nervosa
13 (1), 291
DOI 10.1038/s41398-023-02585-1, PubMed 37658054
Boen R, Kaufmann T, Frei O, van der Meer D, Djurovic S, Andreassen OA, Selmer KK, Alnæs D, Sønderby IE (2023)
No signs of neurodegenerative effects in 15q11.2 BP1-BP2 copy number variant carriers in the UK Biobank
13 (1), 61
DOI 10.1038/s41398-023-02358-w, PubMed 36807331
Cheng W, Parker N, Karadag N, Koch E, Hindley G, Icick R, Shadrin A, O'Connell KS, Bjella T, Bahrami S, Rahman Z, Tesfaye M, Jaholkowski P, Rødevand L, Holen B, Lagerberg TV, Steen NE, Djurovic S, Dale AM, Frei O, Smeland OB, Andreassen OA (2023)
The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study
10 (6), 441-451
DOI 10.1016/S2215-0366(23)00143-8, PubMed 37208114
de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, Sims R, Bellenguez C, Quintela I, González-Perez A, Calero M, Franco-Macías E, Macías J, Blesa R, Cervera-Carles L, Menéndez-González M et al. (2023)
Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
14 (1), 716
DOI 10.1038/s41467-023-36192-x, PubMed 36759603
Docherty AR, Mullins N, Ashley-Koch AE, Qin X, Coleman JRI, Shabalin A, Kang J, Murnyak B, Wendt F, Adams M, Campos AI, DiBlasi E, Fullerton JM, Kranzler HR, Bakian AV, Monson ET, Rentería ME, Walss-Bass C, Andreassen OA, Behera C, Bulik CM, Edenberg HJ, Kessler RC, Mann JJ, Nurnberger JI et al. (2023)
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors
180 (10), 723-738
DOI 10.1176/appi.ajp.21121266, PubMed 37777856
Fominykh V, Shadrin AA, Jaholkowski PP, Bahrami S, Athanasiu L, Wightman DP, Uffelmann E, Posthuma D, Selbæk G, Dale AM, Djurovic S, Frei O, Andreassen OA (2023)
Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system
183, 106174
DOI 10.1016/j.nbd.2023.106174, PubMed 37286172
Hindley G, Drange OK, Lin A, Kutrolli G, Shadrin AA, Parker N, O'Connell KS, Rødevand L, Cheng W, Bahrami S, Karadag N, Holen B, Jaholkowski P, Woldeyohannes MT, Djurovic S, Dale AM, Frei O, Ueland T, Smeland OB, Andreassen OA (2023)
Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders
157, 106368
DOI 10.1016/j.psyneuen.2023.106368, PubMed 37659117
Hindley G, Shadrin AA, van der Meer D, Parker N, Cheng W, O'Connell KS, Bahrami S, Lin A, Karadag N, Holen B, Bjella T, Deary IJ, Davies G, Hill WD, Bressler J, Seshadri S, Fan CC, Ueland T, Djurovic S, Smeland OB, Frei O, Dale AM, Andreassen OA (2023)
Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy
7 (9), 1584-1600
DOI 10.1038/s41562-023-01630-9, PubMed 37365406
Hjell G, Rokicki J, Szabo A, Holst R, Tesli N, Bell C, Fischer-Vieler T, Werner MCF, Lunding SH, Ormerod MBEG, Johansen IT, Djurovic S, Ueland T, Andreassen OA, Melle I, Lagerberg TV, Mørch-Johnsen L, Steen NE, Haukvik UK (2023)
Impulsivity across severe mental disorders: a cross-sectional study of immune markers and psychopharmacotherapy
23 (1), 659
DOI 10.1186/s12888-023-05154-4, PubMed 37674162
Holen B, Kutrolli G, Shadrin AA, Icick R, Hindley G, Rødevand L, O'Connell KS, Frei O, Parker N, Tesfaye M, Deak JD, Jahołkowski P, Dale AM, Djurovic S, Andreassen OA, Smeland OB (2023)
Genome-wide analyses reveal shared genetic architecture and novel risk loci between opioid use disorder and general cognitive ability
256, 111058
DOI 10.1016/j.drugalcdep.2023.111058, PubMed 38244365
Holen B, Shadrin AA, Icick R, Filiz TT, Hindley G, Rødevand L, O'Connell KS, Hagen E, Frei O, Bahrami S, Cheng W, Parker N, Tesfaye M, Jahołkowski P, Karadag N, Dale AM, Djurovic S, Smeland OB, Andreassen OA (2023)
Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression
28 (6), e13282
DOI 10.1111/adb.13282, PubMed 37252880
Hope S, Shadrin AA, Lin A, Bahrami S, Rødevand L, Frei O, Hübenette SJ, Cheng W, Hindley G, Nag H, Ulstein L, Efrim-Budisteanu M, O'Connell K, Dale AM, Djurovic S, Nærland T, Andreassen OA (2023)
Bidirectional genetic overlap between autism spectrum disorder and cognitive traits
13 (1), 295
DOI 10.1038/s41398-023-02563-7, PubMed 37709755
Jaholkowski P, Hindley GFL, Shadrin AA, Tesfaye M, Bahrami S, Nerhus M, Rahman Z, O'Connell KS, Holen B, Parker N, Cheng W, Lin A, Rødevand L, Karadag N, Frei O, Djurovic S, Dale AM, Smeland OB, Andreassen OA (2023)
Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci
49 (6), 1654-1664
DOI 10.1093/schbul/sbad063, PubMed 37163672
Jaholkowski P, Shadrin AA, Jangmo A, Frei E, Tesfaye M, Hindley GFL, Haram M, Rahman Z, Athanasiu L, Bakken NR, Holen B, Fominykh V, Kutrolli G, Parekh P, Parker N, Rødevand L, Birkenæs V, Djurovic S, Frei O, O'Connell KS, Smeland OB, Tesli M, Andreassen OA (2023)
Associations Between Symptoms of Premenstrual Disorders and Polygenic Liability for Major Psychiatric Disorders
80 (7), 738-742
DOI 10.1001/jamapsychiatry.2023.1137, PubMed 37163253
Jensen SB, Sheikh MA, Akkouh IA, Szabo A, O'Connell KS, Lekva T, Engh JA, Agartz I, Elvsåshagen T, Ormerod MBEG, Weibell MA, Johnsen E, Kroken RA, Melle I, Drange OK, Nærland T, Vaaler AE, Westlye LT, Aukrust P, Djurovic S, Eiel Steen N, Andreassen OA, Ueland T (2023)
Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness
49 (3), 635-645
DOI 10.1093/schbul/sbac191, PubMed 36462169
Karadag N, Shadrin AA, O'Connell KS, Hindley GFL, Rahman Z, Parker N, Bahrami S, Fominykh V, Cheng W, Holen B, Alvestad S, Taubøll E, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB (2023)
Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders
146 (8), 3392-3403
DOI 10.1093/brain/awad038, PubMed 36757824
Mlakar V, Birkenæs V, Elvsaashagen T, Ormerod MBEG, Quintana DS, Ueland T, Melle I, Lagerberg TV, Djurovic S, Martin-Ruiz C, Steen NE, Andreassen OA, Aas M (2023)
Telomere length and verbal learning in bipolar disorders
339, 555-560
DOI 10.1016/j.jad.2023.07.087, PubMed 37459977
O'Connell KS, Koch E, Lenk HÇ, Akkouh IA, Hindley G, Jaholkowski P, Smith RL, Holen B, Shadrin AA, Frei O, Smeland OB, Steen NE, Dale AM, Molden E, Djurovic S, Andreassen OA (2023)
Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia
325, 115217
DOI 10.1016/j.psychres.2023.115217, PubMed 37146461
Oddsson A, Sulem P, Sveinbjornsson G, Arnadottir GA, Steinthorsdottir V, Halldorsson GH, Atlason BA, Oskarsson GR, Helgason H, Nielsen HS, Westergaard D, Karjalainen JM, Katrinardottir H, Fridriksdottir R, Jensson BO, Tragante V, Ferkingstad E, Jonsson H, Gudjonsson SA, Beyter D, Moore KHS, Thordardottir HB, Kristmundsdottir S, Stefansson OA, Rantapää-Dahlqvist S et al. (2023)
Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
14 (1), 3453
DOI 10.1038/s41467-023-38951-2, PubMed 37301908
Oddsson A, Sulem P, Sveinbjornsson G, Arnadottir GA, Steinthorsdottir V, Halldorsson GH, Atlason BA, Oskarsson GR, Helgason H, Nielsen HS, Westergaard D, Karjalainen JM, Katrinardottir H, Fridriksdottir R, Jensson BO, Tragante V, Ferkingstad E, Jonsson H, Gudjonsson SA, Beyter D, Moore KHS, Thordardottir HB, Kristmundsdottir S, Stefansson OA, Rantapää-Dahlqvist S et al. (2023)
Publisher Correction: Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
14 (1), 3923
DOI 10.1038/s41467-023-39492-4, PubMed 37400429
Osete JR, Akkouh IA, Ievglevskyi O, Vandenberghe M, de Assis DR, Ueland T, Kondratskaya E, Holen B, Szabo A, Hughes T, Smeland OB, Steen VM, Andreassen OA, Djurovic S (2023)
Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids
28 (7), 3033-3043
DOI 10.1038/s41380-023-01944-0, PubMed 36653674
Parker N, Cheng W, Hindley GFL, O'Connell KS, Karthikeyan S, Holen B, Shadrin AA, Rahman Z, Karadag N, Bahrami S, Lin A, Steen NE, Ueland T, Aukrust P, Djurovic S, Dale AM, Smeland OB, Frei O, Andreassen OA (2023)
Genetic Overlap Between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts
95 (1), 62-71
DOI 10.1016/j.biopsych.2023.06.008, PubMed 37348803
Parker N, Cheng W, Hindley GFL, Parekh P, Shadrin AA, Maximov II, Smeland OB, Djurovic S, Dale AM, Westlye LT, Frei O, Andreassen OA (2023)
Psychiatric disorders and brain white matter exhibit genetic overlap implicating developmental and neural cell biology
28 (11), 4924-4932
DOI 10.1038/s41380-023-02264-z, PubMed 37759039
Rødevand L, Rahman Z, Hindley GFL, Smeland OB, Frei O, Tekin TF, Kutrolli G, Bahrami S, Hoseth EZ, Shadrin A, Lin A, Djurovic S, Dale AM, Steen NE, Andreassen OA (2023)
Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors
180 (11), 815-826
DOI 10.1176/appi.ajp.20220660, PubMed 37752828
Steen NE, Rahman Z, Szabo A, Hindley GFL, Parker N, Cheng W, Lin A, O'Connell KS, Sheikh MA, Shadrin A, Bahrami S, Karthikeyan S, Hoseth EZ, Dale AM, Aukrust P, Smeland OB, Ueland T, Frei O, Djurovic S, Andreassen OA (2023)
Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities
49 (5), 1345-1354
DOI 10.1093/schbul/sbad082, PubMed 37319439
Tesfaye M, Jaholkowski P, Hindley GFL, Shadrin AA, Rahman Z, Bahrami S, Lin A, Holen B, Parker N, Cheng W, Rødevand L, Frei O, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Andreassen OA (2023)
Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis
15 (1), 60
DOI 10.1186/s13073-023-01212-4, PubMed 37528461
Torsvik A, Brattbakk HR, Trentani A, Holdhus R, Stansberg C, Bartz-Johannessen CA, Hughes T, Steen NE, Melle I, Djurovic S, Andreassen OA, Steen VM (2023)
Patients with schizophrenia and bipolar disorder display a similar global gene expression signature in whole blood that reflects elevated proportion of immature neutrophil cells with association to lipid changes
13 (1), 147
DOI 10.1038/s41398-023-02442-1, PubMed 37147304
Villar JD, Stavrum AK, Spindola LM, Torsvik A, Bjella T, Steen NE, Djurovic S, Andreassen OA, Steen VM, Le Hellard S (2023)
Differences in white blood cell proportions between schizophrenia cases and controls are influenced by medication and variations in time of day
13 (1), 211
DOI 10.1038/s41398-023-02507-1, PubMed 37330513
Wortinger LA, Shadrin AA, Szabo A, Nerland S, Smelror RE, Jørgensen KN, Barth C, Andreou D, Thoresen M, Andreassen OA, Djurovic S, Ursini G, Agartz I (2023)
The impact of placental genomic risk for schizophrenia and birth asphyxia on brain development
13 (1), 343
DOI 10.1038/s41398-023-02639-4, PubMed 37938559
Aas M, Andreassen OA, Gjerstad J, Rødevand L, Hjell G, Johansen IT, Lunding SH, Ormerod MBEG, Lagerverg TV, Steen NE, Djurovic S, Akkouh I (2023)
Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders
13 (1), 13845
DOI 10.1038/s41598-023-40310-6, PubMed 37620394
Akkouh IA, Hribkova H, Grabiec M, Budinska E, Szabo A, Kasparek T, Andreassen OA, Sun YM, Djurovic S (2022)
Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response
48 (1), 190-198
DOI 10.1093/schbul/sbab092, PubMed 34357384
Bahrami S, Hindley G, Winsvold BS, O'Connell KS, Frei O, Shadrin A, Cheng W, Bettella F, Rødevand L, Odegaard KJ, Fan CC, Pirinen MJ, Hautakangas HM, HUNT All-In Headache, Dale AM, Djurovic S, Smeland OB, Andreassen OA (2022)
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools
145 (1), 142-153
DOI 10.1093/brain/awab267, PubMed 34273149
Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D et al. (2022)
New insights into the genetic etiology of Alzheimer's disease and related dementias
54 (4), 412-436
DOI 10.1038/s41588-022-01024-z, PubMed 35379992
Birkenes V, Elvsahagen T, Westlye LT, Hoegh MC, Haram M, Werner MCF, Quintana DS, Lunding SH, Martin-Ruiz C, Agartz I, Djurovic S, Steen NE, Andreassen OA, Aas M (2022)
Telomeres are shorter and associated with number of suicide attempts in affective disorders
J. Affect. Disord., 297, 1032-1039
DOI 10.1016/j.jad.2021.08.135
Cheng W, van der Meer D, Parker N, Hindley G, O'Connell KS, Wang Y, Shadrin AA, Alnæs D, Bahrami S, Lin A, Karadag N, Holen B, Fernandez-Cabello S, Fan CC, Dale AM, Djurovic S, Westlye LT, Frei O, Smeland OB, Andreassen OA (2022)
Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood
27 (12), 5167-5176
DOI 10.1038/s41380-022-01751-z, PubMed 36100668
Elkjaer Greenwood Ormerod MB, Ueland T, Frogner Werner MC, Hjell G, Rødevand L, Sæther LS, Lunding SH, Johansen IT, Ueland T, Lagerberg TV, Melle I, Djurovic S, Andreassen OA, Steen NE (2022)
Composite immune marker scores associated with severe mental disorders and illness course
24, 100483
DOI 10.1016/j.bbih.2022.100483, PubMed 35856063
Engh JA, Ueland T, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Hope S, Høegh MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Wedervang-Resell K, Weibell MA, Westlye LT, Djurovic S et al. (2022)
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
48 (1), 37-46
DOI 10.1093/schbul/sbab106, PubMed 34499169
Hindley G, Frei O, Shadrin AA, Cheng W, O'Connell KS, Icick R, Parker N, Bahrami S, Karadag N, Roelfs D, Holen B, Lin A, Fan CC, Djurovic S, Dale AM, Smeland OB, Andreassen OA (2022)
Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation
179 (11), 833-843
DOI 10.1176/appi.ajp.21101051, PubMed 36069018
Hindley G, O'Connell KS, Rahman Z, Frei O, Bahrami S, Shadrin A, Høegh MC, Cheng W, Karadag N, Lin A, Rødevand L, Fan CC, Djurovic S, Lagerberg TV, Dale AM, Smeland OB, Andreassen OA (2022)
The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis
189 (6), 207-218
DOI 10.1002/ajmg.b.32907, PubMed 35841185
Hjell G, Szabo A, Mørch-Johnsen L, Holst R, Tesli N, Bell C, Fischer-Vieler T, Werner MCF, Lunding SH, Ormerod MBEG, Johansen IT, Dieset I, Djurovic S, Melle I, Ueland T, Andreassen OA, Steen NE, Haukvik UK (2022)
Interleukin-18 signaling system links to agitation in severe mental disorders
140, 105721
DOI 10.1016/j.psyneuen.2022.105721, PubMed 35301151
Holmgren A, Hansson L, Bjerkaas-Kjeldal K, Impellizzeri AAR, Gilfillan GD, Djurovic S, Hughes T (2022)
Mapping the expression of an ANK3 isoform associated with bipolar disorder in the human brain
12 (1), 45
DOI 10.1038/s41398-022-01784-6, PubMed 35091539
Icick R, Shadrin A, Holen B, Karadag N, Lin A, Hindley G, O'Connell K, Frei O, Bahrami S, Høegh MC, Cheng W, Fan CC, Djurovic S, Dale AM, Lagerberg TV, Smeland OB, Andreassen OA (2022)
Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings
47 (11), 1883-1891
DOI 10.1038/s41386-022-01401-6, PubMed 35953530
Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, Zettergren A, Mishra A, Ali M, Andrade V, Bellenguez C, Kleineidam L, Küçükali F, Sung YJ, Tesí N, Vromen EM, Wightman DP, Alcolea D, Alegret M, Alvarez I, Amouyel P, Athanasiu L, Bahrami S, Bailly H, Belbin O et al. (2022)
Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers
144 (5), 821-842
DOI 10.1007/s00401-022-02454-z, PubMed 36066633
Johannessen J, Nærland T, Hope S, Torske T, Kaale A, Wirgenes KV, Malt E, Djurovic S, Rietschel M, Andreassen OA (2022)
Correction to: Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health
30 (10), 1198
DOI 10.1038/s41431-021-01021-6, PubMed 34903869
Motazedi E, Cheng W, Thomassen JQ, Frei O, Rongve A, Athanasiu L, Bahrami S, Shadrin A, Ulstein I, Stordal E, Brækhus A, Saltvedt I, Sando SB, O'Connell KS, Hindley G, van der Meer D, Bergh S, Nordestgaard BG, Tybjærg-Hansen A, Bråthen G, Pihlstrøm L, Djurovic S, Frikke-Schmidt R, Fladby T, Aarsland D et al. (2022)
Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer's Disease in Nordic Populations
88 (4), 1533-1544
DOI 10.3233/JAD-220174, PubMed 35848024
Sheikh MA, O'Connell KS, Lekva T, Szabo A, Akkouh IA, Osete JR, Agartz I, Engh JA, Andreou D, Boye B, Bøen E, Elvsåshagen T, Hope S, Frogner Werner MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Melle I, Drange OK, Morken G, Nærland T, Sørensen K, Vaaler AE, Weibell MA et al. (2022)
Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
93 (2), 187-196
DOI 10.1016/j.biopsych.2022.06.029, PubMed 36182530
Sæther LS, Ueland T, Haatveit B, Maglanoc LA, Szabo A, Djurovic S, Aukrust P, Roelfs D, Mohn C, Ormerod MBEG, Lagerberg TV, Steen NE, Melle I, Andreassen OA, Ueland T (2022)
Inflammation and cognition in severe mental illness: patterns of covariation and subgroups
28 (3), 1284-1292
DOI 10.1038/s41380-022-01924-w, PubMed 36577840
Torgersen K, Rahman Z, Bahrami S, Hindley GFL, Parker N, Frei O, Shadrin A, O'Connell KS, Tesli M, Smeland OB, Munkhaugen J, Djurovic S, Dammen T, Andreassen OA (2022)
Shared genetic loci between depression and cardiometabolic traits
18 (5), e1010161
DOI 10.1371/journal.pgen.1010161, PubMed 35560157
Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G et al. (2022)
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
604 (7906), 502-508
DOI 10.1038/s41586-022-04434-5, PubMed 35396580
van der Meer D, Shadrin AA, O'Connell K, Bettella F, Djurovic S, Wolfers T, Alnæs D, Agartz I, Smeland OB, Melle I, Sánchez JM, Linden DEJ, Dale AM, Westlye LT, Andreassen OA, Frei O, Kaufmann T (2022)
Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology
92 (4), 291-298
DOI 10.1016/j.biopsych.2021.12.007, PubMed 35164939
Wang S, Rhijn JV, Akkouh I, Kogo N, Maas N, Bleeck A, Ortiz IS, Lewerissa E, Wu KM, Schoenmaker C, Djurovic S, van Bokhoven H, Kleefstra T, Nadif Kasri N, Schubert D (2022)
Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
39 (5), 110790
DOI 10.1016/j.celrep.2022.110790, PubMed 35508131
Werner MCF, Wirgenes KV, Shadrin A, Lunding SH, Rødevand L, Hjell G, Ormerod MBEG, Haram M, Agartz I, Djurovic S, Melle I, Aukrust P, Ueland T, Andreassen OA, Steen NE (2022)
Immune marker levels in severe mental disorders: associations with polygenic risk scores of related mental phenotypes and psoriasis
12 (1), 38
DOI 10.1038/s41398-022-01811-6, PubMed 35082268
Werner MCF, Wirgenes KV, Shadrin AA, Lunding SH, Rødevand L, Hjell G, Ormerod MBEG, Haram M, Agartz I, Djurovic S, Melle I, Aukrust P, Ueland T, Andreassen OA, Steen NE (2022)
Limited association between infections, autoimmune disease and genetic risk and immune activation in severe mental disorders
116, 110511
DOI 10.1016/j.pnpbp.2022.110511, PubMed 35063598
Wightman DP, Jansen IE, Savage JE, Shadrin AA, Bahrami S, Holland D, Rongve A, Børte S, Winsvold BS, Drange OK, Martinsen AE, Skogholt AH, Willer C, Bråthen G, Bosnes I, Nielsen JB, Fritsche LG, Thomas LF, Pedersen LM, Gabrielsen ME, Johnsen MB, Meisingset TW, Zhou W, Proitsi P, Hodges A et al. (2022)
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
54 (7), 1062
DOI 10.1038/s41588-022-01126-8, PubMed 35726068
Wilson MN, Thunemann M, Liu X, Lu Y, Puppo F, Adams JW, Kim JH, Ramezani M, Pizzo DP, Djurovic S, Andreassen OA, Mansour AA, Gage FH, Muotri AR, Devor A, Kuzum D (2022)
Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex
13 (1), 7945
DOI 10.1038/s41467-022-35536-3, PubMed 36572698
Akkouh IA, Hughes T, Steen VM, Glover JC, Andreassen OA, Djurovic S, Szabo A (2021)
Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia
94, 235-244
DOI 10.1016/j.bbi.2021.01.037, PubMed 33571628
Andreou D, Steen NE, Jørgensen KN, Smelror RE, Wedervang-Resell K, Nerland S, Westlye LT, Nærland T, Myhre AM, Joa I, Reitan SMK, Vaaler A, Morken G, Bøen E, Elvsåshagen T, Boye B, Malt UF, Aukrust P, Skrede S, Kroken RA, Johnsen E, Djurovic S, Andreassen OA, Ueland T, Agartz I (2021)
Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
53 (4), 1479-1488
DOI 10.1017/S0033291721003056, PubMed 35387700
Bahrami S, Shadrin A, Frei O, O'Connell KS, Bettella F, Krull F, Fan CC, Røssberg JI, Hindley G, Ueland T, Dale AM, Djurovic S, Steen NE, Smeland OB, Andreassen OA (2021)
Genetic loci shared between major depression and intelligence with mixed directions of effect
5 (6), 795-801
DOI 10.1038/s41562-020-01031-2, PubMed 33462475
Beck D, de Lange AG, Pedersen ML, Alnaes D, Maximov II, Voldsbekk I, Richard G, Sanders AM, Ulrichsen KM, Dørum ES, Kolskår KK, Høgestøl EA, Steen NE, Djurovic S, Andreassen OA, Nordvik JE, Kaufmann T, Westlye LT (2021)
Cardiometabolic risk factors associated with brain age and accelerate brain ageing
43 (2), 700-720
DOI 10.1002/hbm.25680, PubMed 34626047
Birkenæs V, Elvsåshagen T, Westlye LT, Høegh MC, Haram M, Werner MCF, Quintana DS, Lunding SH, Martin-Ruiz C, Agartz I, Djurovic S, Steen NE, Andreassen OA, Aas M (2021)
Telomeres are shorter and associated with number of suicide attempts in affective disorders
295, 1032-1039
DOI 10.1016/j.jad.2021.08.135, PubMed 34706411
Blokland GAM, Grove J, Chen CY, Cotsapas C, Tobet S, Handa R, Schizophrenia Working Group of the Psychiatric Genomics Consortium, St Clair D, Lencz T, Mowry BJ, Periyasamy S, Cairns MJ, Tooney PA, Wu JQ, Kelly B, Kirov G, Sullivan PF, Corvin A, Riley BP, Esko T, Milani L, Jönsson EG, Palotie A, Ehrenreich H, Begemann M et al. (2021)
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
91 (1), 102-117
DOI 10.1016/j.biopsych.2021.02.972, PubMed 34099189
Cheng W, Frei O, van der Meer D, Wang Y, O'Connell KS, Chu Y, Bahrami S, Shadrin AA, Alnæs D, Hindley GFL, Lin A, Karadag N, Fan CC, Westlye LT, Kaufmann T, Molden E, Dale AM, Djurovic S, Smeland OB, Andreassen OA (2021)
Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness
78 (9), 1020-1030
DOI 10.1001/jamapsychiatry.2021.1435, PubMed 34160554
de Assis DR, Szabo A, Osete JR, Puppo F, O'Connell KS, Akkouh IA, Hughes T, Frei E, Andreassen OA, Djurovic S (2021)
Using iPSC Models to Understand the Role of Estrogen in Neuron-Glia Interactions in Schizophrenia and Bipolar Disorder
Cells, 10 (2), 209
DOI 10.3390/cells10020209
de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, Sims R, Bellenguez C, Quintela I, González-Perez A, Calero M, Franco-Macías E, Macías J, Blesa R, Cervera-Carles L, Menéndez-González M et al. (2021)
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
12 (1), 3417
DOI 10.1038/s41467-021-22491-8, PubMed 34099642
DeMichele-Sweet MAA, Klei L, Creese B, Harwood JC, Weamer EA, McClain L, Sims R, Hernandez I, Moreno-Grau S, Tárraga L, Boada M, Alarcón-Martín E, Valero S, NIA-LOAD Family Based Study Consortium, Alzheimer’s Disease Genetics Consortium (ADGC), Liu Y, Hooli B, Aarsland D, Selbaek G, Bergh S, Rongve A, Saltvedt I, Skjellegrind HK, Engdahl B, Stordal E, Andreassen OA et al. (2021)
Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease
26 (10), 5797-5811
DOI 10.1038/s41380-021-01152-8, PubMed 34112972
Fjukstad KK, Athanasiu L, Bahrami S, O'Connell KS, van der Meer D, Bettella F, Dieset I, Steen NE, Djurovic S, Spigset O, Andreassen OA (2021)
Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study
21 (5), 574-585
DOI 10.1038/s41397-021-00234-8, PubMed 33824429
Hindley G, Bahrami S, Steen NE, O'Connell KS, Frei O, Shadrin A, Bettella F, Rødevand L, Fan CC, Dale AM, Djurovic S, Smeland OB, Andreassen OA (2021)
Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking
11 (1), 466
DOI 10.1038/s41398-021-01576-4, PubMed 34497263
Johannessen J, Nærland T, Hope S, Torske T, Kaale A, Wirgenes KV, Malt E, Djurovic S, Rietschel M, Andreassen OA (2021)
Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health
30 (10), 1138-1146
DOI 10.1038/s41431-021-00966-y, PubMed 34776508
Kalman JL, Olde Loohuis LM, Vreeker A, McQuillin A, Stahl EA, Ruderfer D, Grigoroiu-Serbanescu M, Panagiotaropoulou G, Ripke S, Bigdeli TB, Stein F, Meller T, Meinert S, Pelin H, Streit F, Papiol S, Adams MJ, Adolfsson R, Adorjan K, Agartz I, Aminoff SR, Anderson-Schmidt H, Andreassen OA, Ardau R, Aubry JM et al. (2021)
Characterisation of age and polarity at onset in bipolar disorder
219 (6), 659-669
DOI 10.1192/bjp.2021.102, PubMed 35048876
Krull F, Akkouh I, Hughes T, Bettella F, Athanasiu L, Smeland OB, O'Connell KS, Brattbakk HR, Steen VM, Steen NE, Djurovic S, Andreassen OA (2021)
Dose-dependent transcriptional effects of lithium and adverse effect burden in a psychiatric cohort
112, 110408
DOI 10.1016/j.pnpbp.2021.110408, PubMed 34320404
Lam M, Chen CY, Ge T, Xia Y, Hill DW, Trampush JW, Yu J, Knowles E, Davies G, Stahl EA, Huckins L, Liewald DC, Djurovic S, Melle I, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I et al. (2021)
Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics
46 (10), 1788-1801
DOI 10.1038/s41386-021-01023-4, PubMed 34035472
Mullins N, Forstner AJ, O'Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, Børte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, Kamitaki N, Kim M, Krebs K, Panagiotaropoulou G, Schilder BM, Sloofman LG, Steinberg S, Trubetskoy V, Winsvold BS, Won HH et al. (2021)
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
53 (6), 817-829
DOI 10.1038/s41588-021-00857-4, PubMed 34002096
Mullins N, Kang J, Campos AI, Coleman JRI, Edwards AC, Galfalvy H, Levey DF, Lori A, Shabalin A, Starnawska A, Su MH, Watson HJ, Adams M, Awasthi S, Gandal M, Hafferty JD, Hishimoto A, Kim M, Okazaki S, Otsuka I, Ripke S, Ware EB, Bergen AW, Berrettini WH, Bohus M et al. (2021)
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
91 (3), 313-327
DOI 10.1016/j.biopsych.2021.05.029, PubMed 34861974
O'Connell KS, Frei O, Bahrami S, Smeland OB, Bettella F, Cheng W, Chu Y, Hindley G, Lin A, Shadrin A, Barrett EA, Lagerberg TV, Steen NE, Dale AM, Djurovic S, Andreassen OA (2021)
Characterizing the Genetic Overlap Between Psychiatric Disorders and Sleep-Related Phenotypes
90 (9), 621-631
DOI 10.1016/j.biopsych.2021.07.007, PubMed 34482950
O'Connell KS, Sønderby IE, Frei O, van der Meer D, Athanasiu L, Smeland OB, Alnæs D, Kaufmann T, Westlye LT, Steen VM, Andreassen OA, Hughes T, Djurovic S (2021)
Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank
52 (15), 1-11 (in press)
DOI 10.1017/S0033291721000179, PubMed 33653435
Osete JR, Akkouh IA, de Assis DR, Szabo A, Frei E, Hughes T, Smeland OB, Steen NE, Andreassen OA, Djurovic S (2021)
Lithium increases mitochondrial respiration in iPSC-derived neural precursor cells from lithium responders
26 (11), 6789-6805
DOI 10.1038/s41380-021-01164-4, PubMed 34075196
Polushina T, Banerjee N, Giddaluru S, Bettella F, Espeseth T, Lundervold AJ, Djurovic S, Cichon S, Hoffmann P, Nöthen MM, Steen VM, Andreassen OA, Le Hellard S (2021)
Identification of pleiotropy at the gene level between psychiatric disorders and related traits
11 (1), 410
DOI 10.1038/s41398-021-01530-4, PubMed 34326310
Puppo F, Sadegh S, Trujillo CA, Thunemann M, Campbell EP, Vandenberghe M, Shan X, Akkouh IA, Miller EW, Bloodgood BL, Silva GA, Dale AM, Einevoll GT, Djurovic S, Andreassen OA, Muotri AR, Devor A (2021)
All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors
15, 671549
DOI 10.3389/fncel.2021.671549, PubMed 34122014
Rødevand L, Bahrami S, Frei O, Chu Y, Shadrin A, O'Connell KS, Smeland OB, Elvsåshagen T, Hindley GFL, Djurovic S, Dale AM, Lagerberg TV, Steen NE, Andreassen OA (2021)
Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes
11 (1), 407
DOI 10.1038/s41398-021-01527-z, PubMed 34301917
Rødevand L, Bahrami S, Frei O, Lin A, Gani O, Shadrin A, Smeland OB, Connell KSO, Elvsåshagen T, Winterton A, Quintana DS, Hindley GFL, Werner MCF, Djurovic S, Dale AM, Lagerberg TV, Steen NE, Andreassen OA (2021)
Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms
11 (1), 3
DOI 10.1038/s41398-020-01142-4, PubMed 33414458
Szabo A, Akkouh IA, Vandenberghe M, Osete JR, Hughes T, Heine V, Smeland OB, Glover JC, Andreassen OA, Djurovic S (2021)
A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia
11 (1), 554
DOI 10.1038/s41398-021-01681-4, PubMed 34716291
Szabo A, O'Connell KS, Ueland T, Sheikh MA, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Engh JA, Hope S, Collier Høegh M, Joa I, Johnsen E, Kroken RA, Vik Lagerberg T, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Sørensen K et al. (2021)
Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation
99, 299-306
DOI 10.1016/j.bbi.2021.10.017, PubMed 34758379
Sønderby IE, Ching CRK, Thomopoulos SI, van der Meer D, Sun D, Villalon-Reina JE, Agartz I, Amunts K, Arango C, Armstrong NJ, Ayesa-Arriola R, Bakker G, Bassett AS, Boomsma DI, Bülow R, Butcher NJ, Calhoun VD, Caspers S, Chow EWC, Cichon S, Ciufolini S, Craig MC, Crespo-Facorro B, Cunningham AC, Dale AM et al. (2021)
Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs
43 (1), 300-328
DOI 10.1002/hbm.25354, PubMed 33615640
Sønderby IE, van der Meer D, Moreau C, Kaufmann T, Walters GB, Ellegaard M, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn NB, Blangero J, Boomsma DI, Brodaty H, Brouwer RM, Bülow R, Bøen R, Cahn W, Calhoun VD, Caspers S, Ching CRK, Cichon S, Ciufolini S et al. (2021)
1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans
11 (1), 182
DOI 10.1038/s41398-021-01213-0, PubMed 33753722
Torgersen K, Bahrami S, Frei O, Shadrin A, Connell KSO, Smeland OB, Munkhaugen J, Djurovic S, Dammen T, Andreassen OA (2021)
Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors
11 (1), 368
DOI 10.1038/s41398-021-01466-9, PubMed 34226488
Watson HJ, Thornton LM, Yilmaz Z, Baker JH, Coleman JRI, Adan RAH, Alfredsson L, Andreassen OA, Ask H, Berrettini WH, Boehnke M, Boehm I, Boni C, Buehren K, Bulant J, Burghardt R, Chang X, Cichon S, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, de Zwaan M, Dedoussis G et al. (2021)
Common Genetic Variation and Age of Onset of Anorexia Nervosa
2 (4), 368-378
DOI 10.1016/j.bpsgos.2021.09.001, PubMed 36324647
Wightman DP, Jansen IE, Savage JE, Shadrin AA, Bahrami S, Holland D, Rongve A, Børte S, Winsvold BS, Drange OK, Martinsen AE, Skogholt AH, Willer C, Bråthen G, Bosnes I, Nielsen JB, Fritsche LG, Thomas LF, Pedersen LM, Gabrielsen ME, Johnsen MB, Meisingset TW, Zhou W, Proitsi P, Hodges A et al. (2021)
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
53 (9), 1276-1282
DOI 10.1038/s41588-021-00921-z, PubMed 34493870
Wightman DP, Jansen IE, Savage JE, Shadrin AA, Bahrami S, Holland D, Rongve A, Børte S, Winsvold BS, Drange OK, Martinsen AE, Skogholt AH, Willer C, Bråthen G, Bosnes I, Nielsen JB, Fritsche LG, Thomas LF, Pedersen LM, Gabrielsen ME, Johnsen MB, Meisingset TW, Zhou W, Proitsi P, Hodges A et al. (2021)
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
53 (12), 1722
DOI 10.1038/s41588-021-00977-x, PubMed 34773122
Wiström ED, O'Connell KS, Karadag N, Bahrami S, Hindley GFL, Lin A, Cheng W, Steen NE, Shadrin A, Frei O, Djurovic S, Dale AM, Andreassen OA, Smeland OB (2021)
Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci
117 (3), 600-610
DOI 10.1111/add.15680, PubMed 34472679
Akkouh IA, Ueland T, Hansson L, Inderhaug E, Hughes T, Steen NE, Aukrust P, Andreassen OA, Szabo A, Djurovic S (2020)
Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells
87, 634-644
DOI 10.1016/j.bbi.2020.02.008, PubMed 32109548
Bahrami S, Steen NE, Shadrin A, O'Connell K, Frei O, Bettella F, Wirgenes KV, Krull F, Fan CC, Dale AM, Smeland OB, Djurovic S, Andreassen OA (2020)
Shared Genetic Loci Between Body Mass Index and Major Psychiatric Disorders: A Genome-wide Association Study
77 (5), 503-512
DOI 10.1001/jamapsychiatry.2019.4188, PubMed 31913414
Córdova-Palomera A, van der Meer D, Kaufmann T, Bettella F, Wang Y, Alnæs D, Doan NT, Agartz I, Bertolino A, Buitelaar JK, Coynel D, Djurovic S, Dørum ES, Espeseth T, Fazio L, Franke B, Frei O, Håberg A, Le Hellard S, Jönsson EG, Kolskår KK, Lund MJ, Moberget T, Nordvik JE, Nyberg L et al. (2020)
Genetic control of variability in subcortical and intracranial volumes
26 (8), 3876-3883
DOI 10.1038/s41380-020-0664-1, PubMed 32047264
Drakulic D, Djurovic S, Syed YA, Trattaro S, Caporale N, Falk A, Ofir R, Heine VM, Chawner SJRA, Rodriguez-Moreno A, van den Bree MBM, Testa G, Petrakis S, Harwood AJ (2020)
Copy number variants (CNVs): a powerful tool for iPSC-based modelling of ASD
11 (1), 42
DOI 10.1186/s13229-020-00343-4, PubMed 32487215
Elvsåshagen T, Bahrami S, van der Meer D, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Beyer MK, Blasi G, Borgwardt S, Boye B, Buitelaar J, Bøen E, Celius EG, Cervenka S, Conzelmann A, Coynel D, Di Carlo P, Djurovic S, Eisenacher S, Espeseth T, Fatouros-Bergman H, Flyckt L, Franke B et al. (2020)
The genetic architecture of human brainstem structures and their involvement in common brain disorders
11 (1), 4016
DOI 10.1038/s41467-020-17376-1, PubMed 32782260
Engen MJ, Lyngstad SH, Ueland T, Simonsen CE, Vaskinn A, Smeland O, Bettella F, Lagerberg TV, Djurovic S, Andreassen OA, Melle I (2020)
Polygenic scores for schizophrenia and general cognitive ability: associations with six cognitive domains, premorbid intelligence, and cognitive composite score in individuals with a psychotic disorder and in healthy controls
10 (1), 416
DOI 10.1038/s41398-020-01094-9, PubMed 33257657
Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Ching CRK, McMahon MAB, Shatokhina N, Zsembik LCP, Thomopoulos SI, Zhu AH, Strike LT, Agartz I, Alhusaini S, Almeida MAA, Alnæs D, Amlien IK, Andersson M, Ard T, Armstrong NJ, Ashley-Koch A, Atkins JR et al. (2020)
The genetic architecture of the human cerebral cortex
367 (6484)
DOI 10.1126/science.aay6690, PubMed 32193296
Halle KK, Bakke O, Djurovic S, Bye A, Ryeng E, Wisloff U, Andreassen OA, Langaas M (2020)
Computationally efficient familywise error rate control in genome-wide association studies using score tests for generalized linear models
Scand. J. Stat., 47 (4), 1090-1113
DOI 10.1111/sjos.12451
Hughes T, Hansson L, Akkouh I, Hajdarevic R, Bringsli JS, Torsvik A, Inderhaug E, Steen VM, Djurovic S (2020)
Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations
10 (1), 9101
DOI 10.1038/s41598-020-65675-w, PubMed 32499510
Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, Almdahl IS, Andersen F, Bergh S, Bettella F, Bjornsson S, Brækhus A, Bråthen G, de Leeuw C, Desikan RS, Djurovic S et al. (2020)
Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
52 (3), 354
DOI 10.1038/s41588-019-0573-x, PubMed 32029921
Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, Buitelaar J, Celius EG, Cervenka S, Conzelmann A, Córdova-Palomera A, Dale AM, de Quervain DJF, Di Carlo P, Djurovic S, Dørum ES et al. (2020)
Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain
23 (2), 295
DOI 10.1038/s41593-019-0553-6, PubMed 31848485
Reponen EJ, Dieset I, Tesli M, Mørch RH, Aas M, Vedal TSJ, Haug E, Drange OK, Steen NE, Hope S, Szabo A, Gohar SM, Wedervang-Resell K, Djurovic S, Melle I, Aukrust P, Andreassen OA, Ueland T (2020)
Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders
11, 672
DOI 10.3389/fpsyt.2020.00672, PubMed 32754070
Richards AL, Pardiñas AF, Frizzati A, Tansey KE, Lynham AJ, Holmans P, Legge SE, Savage JE, Agartz I, Andreassen OA, Blokland GAM, Corvin A, Cosgrove D, Degenhardt F, Djurovic S, Espeseth T, Ferraro L, Gayer-Anderson C, Giegling I, van Haren NE, Hartmann AM, Hubert JJ, Jönsson EG, Konte B, Lennertz L et al. (2020)
The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia
46 (2), 336-344
DOI 10.1093/schbul/sbz061, PubMed 31206164
Shadrin AA, Frei O, Smeland OB, Bettella F, O'Connell KS, Gani O, Bahrami S, Uggen TKE, Djurovic S, Holland D, Andreassen OA, Dale AM (2020)
Phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories revealed by AI-MiXeR
36 (18), 4749-4756
DOI 10.1093/bioinformatics/btaa568, PubMed 32539089
Smeland OB, Bahrami S, Frei O, Shadrin A, O'Connell K, Savage J, Watanabe K, Krull F, Bettella F, Steen NE, Ueland T, Posthuma D, Djurovic S, Dale AM, Andreassen OA (2020)
Correction: Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
25 (4), 914
DOI 10.1038/s41380-019-0456-7, PubMed 31308466
Smeland OB, Shadrin A, Bahrami S, Broce I, Tesli M, Frei O, Wirgenes KV, O'Connell KS, Krull F, Bettella F, Steen NE, Sugrue L, Wang Y, Svenningsson P, Sharma M, Pihlstrøm L, Toft M, O'Donovan M, Djurovic S, Desikan R, Dale AM, Andreassen OA (2020)
Genome-wide Association Analysis of Parkinson's Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci
89 (3), 227-235
DOI 10.1016/j.biopsych.2020.01.026, PubMed 32201043
Smith RL, O'Connell K, Athanasiu L, Djurovic S, Kringen MK, Andreassen OA, Molden E (2020)
Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits
10 (1), 198
DOI 10.1038/s41398-020-00888-1, PubMed 32555152
Smith RL, O'Connell K, Athanasiu L, Djurovic S, Kringen MK, Andreassen OA, Molden E (2020)
Correction: Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits
10 (1), 366
DOI 10.1038/s41398-020-01061-4, PubMed 33139722
Szabo A, Akkouh IA, Ueland T, Lagerberg TV, Dieset I, Bjella T, Aukrust P, Le Hellard S, Stavrum AK, Melle I, Andreassen OA, Djurovic S (2020)
Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder
11, 642
DOI 10.3389/fpsyt.2020.00642, PubMed 32714224
Sønderby IE, Gústafsson Ó, Doan NT, Hibar DP, Martin-Brevet S, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn N, Blangero J, Boomsma DI, Bralten J, Brattbak HR, Brodaty H, Brouwer RM, Bülow R, Calhoun V, Caspers S, Cavalleri G, Chen CH, Cichon S, Ciufolini S et al. (2020)
Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
25 (3), 692-695
DOI 10.1038/s41380-019-0358-8, PubMed 30705424
Werner MCF, Wirgenes KV, Haram M, Bettella F, Lunding SH, Rødevand L, Hjell G, Agartz I, Djurovic S, Melle I, Andreassen OA, Steen NE (2020)
Indicated association between polygenic risk score and treatment-resistance in a naturalistic sample of patients with schizophrenia spectrum disorders
218, 55-62
DOI 10.1016/j.schres.2020.03.006, PubMed 32171635
Writing Committee for the ENIGMA-CNV Working Group, van der Meer D, Sønderby IE, Kaufmann T, Walters GB, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn NB, Blangero J, Boomsma DI, Brodaty H, Brouwer RM, Bülow R, Cahn W, Calhoun VD, Caspers S, Cavalleri GL, Ching CRK, Cichon S, Ciufolini S, Corvin A et al. (2020)
Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition
77 (4), 420-430
DOI 10.1001/jamapsychiatry.2019.3779, PubMed 31665216
Akkouh IA, Skrede S, Holmgren A, Ersland KM, Hansson L, Bahrami S, Andreassen OA, Steen VM, Djurovic S, Hughes T (2019)
Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study
45 (6), 947-955
DOI 10.1038/s41386-019-0556-8, PubMed 31652432
Alnæs D, Kaufmann T, van der Meer D, Córdova-Palomera A, Rokicki J, Moberget T, Bettella F, Agartz I, Barch DM, Bertolino A, Brandt CL, Cervenka S, Djurovic S, Doan NT, Eisenacher S, Fatouros-Bergman H, Flyckt L, Di Giorgio A, Haatveit B, Jönsson EG, Kirsch P, Lund MJ, Meyer-Lindenberg A, Pergola G, Schwarz E et al. (2019)
Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk
76 (7), 739-748
DOI 10.1001/jamapsychiatry.2019.0257, PubMed 30969333
Creese B, Vassos E, Bergh S, Athanasiu L, Johar I, Rongve A, Medbøen IT, Vasconcelos Da Silva M, Aakhus E, Andersen F, Bettella F, Braekhus A, Djurovic S, Paroni G, Proitsi P, Saltvedt I, Seripa D, Stordal E, Fladby T, Aarsland D, Andreassen OA, Ballard C, Selbaek G, AddNeuroMed consortium and the Alzheimer’s Disease Neuroimaging Initiative (2019)
Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease
9 (1), 273
DOI 10.1038/s41398-019-0592-5, PubMed 31641104
Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C et al. (2019)
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
10 (1), 2068
DOI 10.1038/s41467-019-10160-w, PubMed 31043617
Drange OK, Smeland OB, Shadrin AA, Finseth PI, Witoelar A, Frei O, Psychiatric Genomics Consortium Bipolar Disorder Working Group, Wang Y, Hassani S, Djurovic S, Dale AM, Andreassen OA (2019)
Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes
13, 220
DOI 10.3389/fnins.2019.00220, PubMed 30930738
Frei O, Holland D, Smeland OB, Shadrin AA, Fan CC, Maeland S, O'Connell KS, Wang Y, Djurovic S, Thompson WK, Andreassen OA, Dale AM (2019)
Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
10 (1), 2417
DOI 10.1038/s41467-019-10310-0, PubMed 31160569
Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S et al. (2019)
Identification of common genetic risk variants for autism spectrum disorder
51 (3), 431-444
DOI 10.1038/s41588-019-0344-8, PubMed 30804558
Gudmundsson OO, Walters GB, Ingason A, Johansson S, Zayats T, Athanasiu L, Sonderby IE, Gustafsson O, Nawaz MS, Jonsson GF, Jonsson L, Knappskog PM, Ingvarsdottir E, Davidsdottir K, Djurovic S, Knudsen GPS, Askeland RB, Haraldsdottir GS, Baldursson G, Magnusson P, Sigurdsson E, Gudbjartsson DF, Stefansson H, Andreassen OA, Haavik J et al. (2019)
Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder
9 (1), 258
DOI 10.1038/s41398-019-0599-y, PubMed 31624239
Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, Almdahl IS, Andersen F, Bergh S, Bettella F, Bjornsson S, Brækhus A, Bråthen G, de Leeuw C, Desikan RS, Djurovic S et al. (2019)
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
51 (3), 404-413
DOI 10.1038/s41588-018-0311-9, PubMed 30617256
Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, Buitelaar J, Celius EG, Cervenka S, Conzelmann A, Córdova-Palomera A, Dale AM, de Quervain DJF, Di Carlo P, Djurovic S, Dørum ES et al. (2019)
Common brain disorders are associated with heritable patterns of apparent aging of the brain
22 (10), 1617-1623
DOI 10.1038/s41593-019-0471-7, PubMed 31551603
Lam M, Hill WD, Trampush JW, Yu J, Knowles E, Davies G, Stahl E, Huckins L, Liewald DC, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Hartmann AM et al. (2019)
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways
105 (2), 334-350
DOI 10.1016/j.ajhg.2019.06.012, PubMed 31374203
McCarthy MJ, Wei H, Nievergelt CM, Stautland A, Maihofer AX, Welsh DK, Shilling P, Alda M, Alliey-Rodriguez N, Anand A, Andreasson OA, Balaraman Y, Berrettini WH, Bertram H, Brennand KJ, Calabrese JR, Calkin CV, Claasen A, Conroy C, Coryell WH, Craig DW, D'Arcangelo N, Demodena A, Djurovic S, Feeder S et al. (2019)
Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder
Neuropsychopharmacology, 44 (3), 620-628
DOI 10.1038/s41386-018-0273-8
Mullins N, Bigdeli TB, Børglum AD, Coleman JRI, Demontis D, Mehta D, Power RA, Ripke S, Stahl EA, Starnawska A, Anjorin A, M.R.C.Psych, Corvin A, Sanders AR, Forstner AJ, Reif A, Koller AC, Świątkowska B, Baune BT, Müller-Myhsok B, Penninx BWJH, Pato C, Zai C, Rujescu D, Hougaard DM et al. (2019)
GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores
176 (8), 651-660
DOI 10.1176/appi.ajp.2019.18080957, PubMed 31164008
Mäki-Marttunen T, Kaufmann T, Elvsåshagen T, Devor A, Djurovic S, Westlye LT, Linne ML, Rietschel M, Schubert D, Borgwardt S, Efrim-Budisteanu M, Bettella F, Halnes G, Hagen E, Næss S, Ness TV, Moberget T, Metzner C, Edwards AG, Fyhn M, Dale AM, Einevoll GT, Andreassen OA (2019)
Biophysical Psychiatry-How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders
10, 534
DOI 10.3389/fpsyt.2019.00534, PubMed 31440172
Mäki-Marttunen T, Krull F, Bettella F, Hagen E, Næss S, Ness TV, Moberget T, Elvsåshagen T, Metzner C, Devor A, Edwards AG, Fyhn M, Djurovic S, Dale AM, Andreassen OA, Einevoll GT (2019)
Alterations in Schizophrenia-Associated Genes Can Lead to Increased Power in Delta Oscillations
29 (2), 875-891
DOI 10.1093/cercor/bhy291, PubMed 30475994
Mørch RH, Dieset I, Færden A, Reponen EJ, Hope S, Hoseth EZ, Gardsjord ES, Aas M, Iversen T, Joa I, Morken G, Agartz I, Melle I, Aukrust P, Djurovic S, Ueland T, Andreassen OA (2019)
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors
49 (10), 1749-1757
DOI 10.1017/S0033291718004142, PubMed 30688187
Mørch RH, Dieset I, Færden A, Reponen EJ, Hope S, Hoseth EZ, Gardsjord ES, Aas M, Iversen T, Joa I, Morken G, Agartz I, Melle I, Aukrust P, Djurovic S, Ueland T, Andreassen OA (2019)
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors - ERRATUM
49 (10), 1758
DOI 10.1017/S0033291719000291, PubMed 30803457
O'Connell KS, Shadrin A, Bahrami S, Smeland OB, Bettella F, Frei O, Krull F, Askeland RB, Walters GB, Davíðsdóttir K, Haraldsdóttir GS, Guðmundsson ÓÓ, Stefánsson H, Fan CC, Steen NE, Reichborn-Kjennerud T, Dale AM, Stefánsson K, Djurovic S, Andreassen OA (2019)
Identification of genetic overlap and novel risk loci for attention-deficit/hyperactivity disorder and bipolar disorder
26 (8), 4055-4065
DOI 10.1038/s41380-019-0613-z, PubMed 31792363
O'Connell KS, Shadrin A, Smeland OB, Bahrami S, Frei O, Bettella F, Krull F, Fan CC, Askeland RB, Knudsen GPS, Halmøy A, Steen NE, Ueland T, Walters GB, Davíðsdóttir K, Haraldsdóttir GS, Guðmundsson ÓÓ, Stefánsson H, Reichborn-Kjennerud T, Haavik J, Dale AM, Stefánsson K, Djurovic S, Andreassen OA (2019)
Identification of Genetic Loci Shared Between Attention-Deficit/Hyperactivity Disorder, Intelligence, and Educational Attainment
87 (12), 1052-1062
DOI 10.1016/j.biopsych.2019.11.015, PubMed 32061372
Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, Carrera N, Legge SE, Bishop S, Cameron D, Hamshere ML, Han J, Hubbard L, Lynham A, Mantripragada K, Rees E, MacCabe JH, McCarroll SA, Baune BT, Breen G, Byrne EM, Dannlowski U, Eley TC, Hayward C, Martin NG, McIntosh AM et al. (2019)
Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
51 (7), 1193
DOI 10.1038/s41588-019-0450-7, PubMed 31160808
Rongve A, Witoelar A, Ruiz A, Athanasiu L, Abdelnour C, Clarimon J, Heilmann-Heimbach S, Hernández I, Moreno-Grau S, de Rojas I, Morenas-Rodríguez E, Fladby T, Sando SB, Bråthen G, Blanc F, Bousiges O, Lemstra AW, van Steenoven I, Londos E, Almdahl IS, Pålhaugen L, Eriksen JA, Djurovic S, Stordal E, Saltvedt I et al. (2019)
GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
9 (1), 7013
DOI 10.1038/s41598-019-43458-2, PubMed 31065058
Rongve A, Witoelar A, Ruiz A, Athanasiu L, Abdelnour C, Clarimon J, Heilmann-Heimbach S, Hernández I, Moreno-Grau S, de Rojas I, Morenas-Rodríguez E, Fladby T, Sando SB, Bråthen G, Blanc F, Bousiges O, Lemstra AW, van Steenoven I, Londos E, Almdahl IS, Pålhaugen L, Eriksen JA, Djurovic S, Stordal E, Saltvedt I et al. (2019)
Author Correction: GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
9 (1), 15168
DOI 10.1038/s41598-019-51827-0, PubMed 31619746
Sanyal N, Lo MT, Kauppi K, Djurovic S, Andreassen OA, Johnson VE, Chen CH (2019)
GWASinlps: non-local prior based iterative SNP selection tool for genome-wide association studies
35 (1), 1-11
DOI 10.1093/bioinformatics/bty472, PubMed 29931045
Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, Teumer A, van der Lee SJ, Yang J, Yanek LR, Lee TV, Li S, Hu Y, Koh JY, Eicher JD, Desrivières S et al. (2019)
Genetic architecture of subcortical brain structures in 38,851 individuals
51 (11), 1624-1636
DOI 10.1038/s41588-019-0511-y, PubMed 31636452
Smeland OB, Bahrami S, Frei O, Shadrin A, O'Connell K, Savage J, Watanabe K, Krull F, Bettella F, Steen NE, Ueland T, Posthuma D, Djurovic S, Dale AM, Andreassen OA (2019)
Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
25 (4), 844-853
DOI 10.1038/s41380-018-0332-x, PubMed 30610197
Smeland OB, Frei O, Shadrin A, O'Connell K, Fan CC, Bahrami S, Holland D, Djurovic S, Thompson WK, Dale AM, Andreassen OA (2019)
Discovery of shared genomic loci using the conditional false discovery rate approach
139 (1), 85-94
DOI 10.1007/s00439-019-02060-2, PubMed 31520123
Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin A et al. (2019)
Genome-wide association study identifies 30 loci associated with bipolar disorder
51 (5), 793-803
DOI 10.1038/s41588-019-0397-8, PubMed 31043756
Steen NE, Dieset I, Hope S, Vedal TSJ, Smeland OB, Matson W, Kaddurah-Daouk R, Agartz I, Melle I, Djurovic S, Jönsson EG, Bogdanov M, Andreassen OA (2019)
Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders
50 (4), 595-606
DOI 10.1017/S0033291719000400, PubMed 30867076
Aas M, Djurovic S, Ueland T, Mørch RH, Fjæra Laskemoen J, Reponen EJ, Cattaneo A, Eiel Steen N, Agartz I, Melle I, Andreassen OA (2019)
The relationship between physical activity, clinical and cognitive characteristics and BDNF mRNA levels in patients with severe mental disorders
20 (7), 567-576
DOI 10.1080/15622975.2018.1557345, PubMed 30560709
Aas M, Elvsåshagen T, Westlye LT, Kaufmann T, Athanasiu L, Djurovic S, Melle I, van der Meer D, Martin-Ruiz C, Steen NE, Agartz I, Andreassen OA (2019)
Telomere length is associated with childhood trauma in patients with severe mental disorders
9 (1), 97
DOI 10.1038/s41398-019-0432-7, PubMed 30898995
Akkouh IA, Ueland T, Andreassen OA, Brattbakk HR, Steen VM, Hughes T, Djurovic S (2018)
Expression of TCN1 in Blood is Negatively Associated with Verbal Declarative Memory Performance
8 (1), 12654
DOI 10.1038/s41598-018-30898-5, PubMed 30139959
Berg AO, Jørgensen KN, Nerhus M, Athanasiu L, Popejoy AB, Bettella F, Norbom LCB, Gurholt TP, Dahl SR, Andreassen OA, Djurovic S, Agartz I, Melle I (2018)
Vitamin D levels, brain volume, and genetic architecture in patients with psychosis
13 (8), e0200250
DOI 10.1371/journal.pone.0200250, PubMed 30142216
Bettella F, Brown AA, Smeland OB, Wang Y, Witoelar A, Buil Demur AA, Thompson WK, Zuber V, Dale AM, Djurovic S, Andreassen OA (2018)
Cross-tissue eQTL enrichment of associations in schizophrenia
13 (9), e0202812
DOI 10.1371/journal.pone.0202812, PubMed 30188921
Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C et al. (2018)
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
9 (1), 2098
DOI 10.1038/s41467-018-04362-x, PubMed 29844566
Dieset I, Mørch RH, Hope S, Hoseth EZ, Reponen EJ, Gran JM, Aas M, Michelsen AE, Reichborn-Kjennerud T, Nesvåg R, Agartz I, Melle I, Aukrust P, Djurovic S, Ueland T, Andreassen OA (2018)
An association between YKL-40 and type 2 diabetes in psychotic disorders
139 (1), 37-45
DOI 10.1111/acps.12971, PubMed 30328100
Dusanov S, Ruzzin J, Kiviranta H, Klemsdal TO, Retterstøl L, Rantakokko P, Airaksinen R, Djurovic S, Tonstad S (2018)
Associations between persistent organic pollutants and metabolic syndrome in morbidly obese individuals
28 (7), 735-742
DOI 10.1016/j.numecd.2018.03.004, PubMed 29699815
Hoseth EZ, Krull F, Dieset I, Mørch RH, Hope S, Gardsjord ES, Steen NE, Melle I, Brattbakk HR, Steen VM, Aukrust P, Djurovic S, Andreassen OA, Ueland T (2018)
Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder
8 (1), 55
DOI 10.1038/s41398-018-0102-1, PubMed 29507296
Hoseth EZ, Krull F, Dieset I, Mørch RH, Hope S, Gardsjord ES, Steen NE, Melle I, Brattbakk HR, Steen VM, Aukrust P, Djurovic S, Andreassen OA, Ueland T (2018)
Attenuated Notch signaling in schizophrenia and bipolar disorder
8 (1), 5349
DOI 10.1038/s41598-018-23703-w, PubMed 29593239
Hughes T, Sønderby IE, Polushina T, Hansson L, Holmgren A, Athanasiu L, Melbø-Jørgensen C, Hassani S, Hoeffding LK, Herms S, Bergen SE, Karlsson R, Song J, Rietschel M, Nöthen MM, Forstner AJ, Hoffmann P, Hultman CM, Landén M, Cichon S, Werge T, Andreassen OA, Le Hellard S, Djurovic S (2018)
Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder
8 (1), 210
DOI 10.1038/s41398-018-0175-x, PubMed 30297702
Kaufmann T, Alnæs D, Brandt CL, Bettella F, Djurovic S, Andreassen OA, Westlye LT (2018)
Stability of the Brain Functional Connectome Fingerprint in Individuals With Schizophrenia
75 (7), 749-751
DOI 10.1001/jamapsychiatry.2018.0844, PubMed 29799905
Kulkarni RU, Vandenberghe M, Thunemann M, James F, Andreassen OA, Djurovic S, Devor A, Miller EW (2018)
In Vivo Two-Photon Voltage Imaging with Sulfonated Rhodamine Dyes
4 (10), 1371-1378
DOI 10.1021/acscentsci.8b00422, PubMed 30410975
Lam M, Trampush JW, Yu J, Knowles E, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek O et al. (2018)
Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018)
21 (5), 394-397
DOI 10.1017/thg.2018.46, PubMed 30001766
Li W, Fan CC, Mäki-Marttunen T, Thompson WK, Schork AJ, Bettella F, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Djurovic S, Dale AM, Andreassen OA, Wang Y (2018)
A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia
177 (4), 454-467
DOI 10.1002/ajmg.b.32634, PubMed 29704319
Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, Carrera N, Legge SE, Bishop S, Cameron D, Hamshere ML, Han J, Hubbard L, Lynham A, Mantripragada K, Rees E, MacCabe JH, McCarroll SA, Baune BT, Breen G, Byrne EM, Dannlowski U, Eley TC, Hayward C, Martin NG, McIntosh AM et al. (2018)
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
50 (3), 381-389
DOI 10.1038/s41588-018-0059-2, PubMed 29483656
Savage JE, Jansen PR, Stringer S, Watanabe K, Bryois J, de Leeuw CA, Nagel M, Awasthi S, Barr PB, Coleman JRI, Grasby KL, Hammerschlag AR, Kaminski JA, Karlsson R, Krapohl E, Lam M, Nygaard M, Reynolds CA, Trampush JW, Young H, Zabaneh D, Hägg S, Hansell NK, Karlsson IK, Linnarsson S et al. (2018)
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
50 (7), 912-919
DOI 10.1038/s41588-018-0152-6, PubMed 29942086
Smeland OB, Wang Y, Frei O, Li W, Hibar DP, Franke B, Bettella F, Witoelar A, Djurovic S, Chen CH, Thompson PM, Dale AM, Andreassen OA (2018)
Genetic Overlap Between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms
44 (4), 854-864
DOI 10.1093/schbul/sbx148, PubMed 29136250
Srinivasan S, Bettella F, Frei O, Hill WD, Wang Y, Witoelar A, Schork AJ, Thompson WK, Davies G, Desikan RS, Deary IJ, Melle I, Ueland T, Dale AM, Djurovic S, Smeland OB, Andreassen OA (2018)
Enrichment of genetic markers of recent human evolution in educational and cognitive traits
8 (1), 12585
DOI 10.1038/s41598-018-30387-9, PubMed 30135563
Stokowy T, Polushina T, Sønderby IE, Karlsson R, Giddaluru S, Le Hellard S, Bergen SE, Sullivan PF, Andreassen OA, Djurovic S, Hultman CM, Steen VM (2018)
Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes
8 (1), 6915
DOI 10.1038/s41598-018-25280-4, PubMed 29720671
Szabo A, Gogolak P, Koncz G, Foldvari Z, Pazmandi K, Miltner N, Poliska S, Bacsi A, Djurovic S, Rajnavolgyi E (2018)
Immunomodulatory capacity of the serotonin receptor 5-HT2B in a subset of human dendritic cells
8 (1), 1765
DOI 10.1038/s41598-018-20173-y, PubMed 29379077
Sønderby IE, Gústafsson Ó, Doan NT, Hibar DP, Martin-Brevet S, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn N, Blangero J, Boomsma DI, Bralten J, Brattbak HR, Brodaty H, Brouwer RM, Bülow R, Calhoun V, Caspers S, Cavalleri G, Chen CH, Cichon S, Ciufolini S et al. (2018)
Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
25 (3), 584-602
DOI 10.1038/s41380-018-0118-1, PubMed 30283035
Thunemann M, Lu Y, Liu X, Kılıç K, Desjardins M, Vandenberghe M, Sadegh S, Saisan PA, Cheng Q, Weldy KL, Lyu H, Djurovic S, Andreassen OA, Dale AM, Devor A, Kuzum D (2018)
Deep 2-photon imaging and artifact-free optogenetics through transparent graphene microelectrode arrays
9 (1), 2035
DOI 10.1038/s41467-018-04457-5, PubMed 29789548
van der Meer D, Rokicki J, Kaufmann T, Córdova-Palomera A, Moberget T, Alnæs D, Bettella F, Frei O, Doan NT, Sønderby IE, Smeland OB, Agartz I, Bertolino A, Bralten J, Brandt CL, Buitelaar JK, Djurovic S, van Donkelaar M, Dørum ES, Espeseth T, Faraone SV, Fernández G, Fisher SE, Franke B, Haatveit B et al. (2018)
Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes
25 (11), 3053-3065
DOI 10.1038/s41380-018-0262-7, PubMed 30279459
Witoelar A, Rongve A, Almdahl IS, Ulstein ID, Engvig A, White LR, Selbæk G, Stordal E, Andersen F, Brækhus A, Saltvedt I, Engedal K, Hughes T, Bergh S, Bråthen G, Bogdanovic N, Bettella F, Wang Y, Athanasiu L, Bahrami S, Le Hellard S, Giddaluru S, Dale AM, Sando SB, Steinberg S et al. (2018)
Meta-analysis of Alzheimer's disease on 9,751 samples from Norway and IGAP study identifies four risk loci
8 (1), 18088
DOI 10.1038/s41598-018-36429-6, PubMed 30591712
Zuber V, Jönsson EG, Frei O, Witoelar A, Thompson WK, Schork AJ, Bettella F, Wang Y, Djurovic S, Smeland OB, Dieset I, Fanous AH, Desikan RS, Küry S, Bézieau S, Dale AM, Mills IG, Andreassen OA (2018)
Identification of shared genetic variants between schizophrenia and lung cancer
8 (1), 674
DOI 10.1038/s41598-017-16481-4, PubMed 29330379
Chen CH, Wang Y, Lo MT, Schork A, Fan CC, Holland D, Kauppi K, Smeland OB, Djurovic S, Sanyal N, Hibar DP, Thompson PM, Thompson WK, Andreassen OA, Dale AM (2017)
Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure
7 (1), 15736
DOI 10.1038/s41598-017-15705-x, PubMed 29147026
Chen H, Ewing CM, Zheng S, Grindedaal EM, Cooney KA, Wiley K, Djurovic S, Andreassen OA, Axcrona K, Mills IG, Xu J, Maehle L, Fosså SD, Isaacs WB (2017)
Genetic factors influencing prostate cancer risk in Norwegian men
78 (3), 186-192
DOI 10.1002/pros.23453, PubMed 29181843
Devor A, Andreassen OA, Wang Y, Mäki-Marttunen T, Smeland OB, Fan CC, Schork AJ, Holland D, Thompson WK, Witoelar A, Chen CH, Desikan RS, McEvoy LK, Djurovic S, Greengard P, Svenningsson P, Einevoll GT, Dale AM (2017)
Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia
22 (6), 792-801
DOI 10.1038/mp.2017.33, PubMed 28348379
Doan NT, Kaufmann T, Bettella F, Jørgensen KN, Brandt CL, Moberget T, Alnæs D, Douaud G, Duff E, Djurovic S, Melle I, Ueland T, Agartz I, Andreassen OA, Westlye LT (2017)
Distinct multivariate brain morphological patterns and their added predictive value with cognitive and polygenic risk scores in mental disorders
15, 719-731
DOI 10.1016/j.nicl.2017.06.014, PubMed 28702349
Hibar DP, Adams HHH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beecham AH, Beiser A, Bernard M, Blanton SH et al. (2017)
Novel genetic loci associated with hippocampal volume
8, 13624
DOI 10.1038/ncomms13624, PubMed 28098162
Hoseth EZ, Ueland T, Dieset I, Birnbaum R, Shin JH, Kleinman JE, Hyde TM, Mørch RH, Hope S, Lekva T, Abraityte AJ, Michelsen AE, Melle I, Westlye LT, Ueland T, Djurovic S, Aukrust P, Weinberger DR, Andreassen OA (2017)
A Study of TNF Pathway Activation in Schizophrenia and Bipolar Disorder in Plasma and Brain Tissue
43 (4), 881-890
DOI 10.1093/schbul/sbw183, PubMed 28049760
Johannessen J, Nærland T, Hope S, Torske T, Høyland AL, Strohmaier J, Heiberg A, Rietschel M, Djurovic S, Andreassen OA (2017)
Parents' Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder-Data from a Norwegian Sample
18 (5)
DOI 10.3390/ijms18051078, PubMed 28524073
Lam M, Trampush JW, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KE et al. (2017)
Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets
21 (9), 2597-2613
DOI 10.1016/j.celrep.2017.11.028, PubMed 29186694
Le Hellard S, Wang Y, Witoelar A, Zuber V, Bettella F, Hugdahl K, Espeseth T, Steen VM, Melle I, Desikan R, Schork AJ, Thompson WK, Dale AM, Djurovic S, Andreassen OA, Schizophrenia Working Group of the Psychiatric Genomics Consortium (2017)
Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment
43 (3), 654-664
DOI 10.1093/schbul/sbw085, PubMed 27338279
Lu Y, Pouget JG, Andreassen OA, Djurovic S, Esko T, Hultman CM, Metspalu A, Milani L, Werge T, Sullivan PF (2017)
Genetic risk scores and family history as predictors of schizophrenia in Nordic registers
48 (7), 1201-1208
DOI 10.1017/S0033291717002665, PubMed 28942743
Mellerup E, Andreassen OA, Bennike B, Dam H, Djurovic S, Jorgensen MB, Kessing LV, Koefoed P, Melle I, Mors O, Moeller GL (2017)
Combinations of genetic variants associated with bipolar disorder
12 (12), e0189739
DOI 10.1371/journal.pone.0189739, PubMed 29267373
Mørch RH, Dieset I, Faerden A, Hope S, Aas M, Nerhus M, Gardsjord ES, Haram M, Falk RS, Joa I, Morken G, Agartz I, Aukrust P, Djurovic S, Melle I, Ueland T, Andreassen OA (2017)
Persistent increase in TNF and IL-1 markers in severe mental disorders suggests trait-related inflammation: a one year follow-up study
136 (4), 400-408
DOI 10.1111/acps.12783, PubMed 28815548
Olafsson S, Stridh P, Bos SD, Ingason A, Euesden J, Sulem P, Thorleifsson G, Gustafsson O, Johannesson A, Geirsson AJ, Thorsson AV, Sigurgeirsson B, Ludviksson BR, Olafsson E, Kristjansdottir H, Jonasson JG, Olafsson JH, Orvar KB, Benediktsson R, Bjarnason R, Kristjansdottir S, Gislason T, Valdimarsson T, Mikaelsdottir E, Sigurdsson S et al. (2017)
Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations
2, 24
DOI 10.1038/s41525-017-0027-2, PubMed 29263835
Polushina T, Giddaluru S, Bettella F, Espeseth T, Lundervold AJ, Djurovic S, Cichon S, Hoffmann P, Nöthen MM, Steen VM, Andreassen OA, Le Hellard S (2017)
Analysis of the joint effect of SNPs to identify independent loci and allelic heterogeneity in schizophrenia GWAS data
7 (12), 1289
DOI 10.1038/s41398-017-0033-2, PubMed 29249828
Shadrin AA, Smeland OB, Zayats T, Schork AJ, Frei O, Bettella F, Witoelar A, Li W, Eriksen JA, Krull F, Djurovic S, Faraone SV, Reichborn-Kjennerud T, Thompson WK, Johansson S, Haavik J, Dale AM, Wang Y, Andreassen OA (2017)
Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment
57 (2), 86-95
DOI 10.1016/j.jaac.2017.11.013, PubMed 29413154
Smeland OB, Frei O, Kauppi K, Hill WD, Li W, Wang Y, Krull F, Bettella F, Eriksen JA, Witoelar A, Davies G, Fan CC, Thompson WK, Lam M, Lencz T, Chen CH, Ueland T, Jönsson EG, Djurovic S, Deary IJ, Dale AM, Andreassen OA, NeuroCHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology) Cognitive Working Group (2017)
Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function
74 (10), 1065-1075
DOI 10.1001/jamapsychiatry.2017.1986, PubMed 28746715
Smeland OB, Wang Y, Lo MT, Li W, Frei O, Witoelar A, Tesli M, Hinds DA, Tung JY, Djurovic S, Chen CH, Dale AM, Andreassen OA (2017)
Identification of genetic loci shared between schizophrenia and the Big Five personality traits
7 (1), 2222
DOI 10.1038/s41598-017-02346-3, PubMed 28533504
Srinivasan S, Bettella F, Hassani S, Wang Y, Witoelar A, Schork AJ, Thompson WK, Collier DA, Desikan RS, Melle I, Dale AM, Djurovic S, Andreassen OA (2017)
Probing the Association between Early Evolutionary Markers and Schizophrenia
12 (1), e0169227
DOI 10.1371/journal.pone.0169227, PubMed 28081145
Trampush JW, Yang ML, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KE et al. (2017)
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
22 (3), 336-345
DOI 10.1038/mp.2016.244, PubMed 28093568
Trampush JW, Yang MLZ, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KE et al. (2017)
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
22 (11), 1651-1652
DOI 10.1038/mp.2017.197, PubMed 29068436
Witoelar A, Jansen IE, Wang Y, Desikan RS, Gibbs JR, Blauwendraat C, Thompson WK, Hernandez DG, Djurovic S, Schork AJ, Bettella F, Ellinghaus D, Franke A, Lie BA, McEvoy LK, Karlsen TH, Lesage S, Morris HR, Brice A, Wood NW, Heutink P, Hardy J, Singleton AB, Dale AM, Gasser T et al. (2017)
Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases
74 (7), 780-792
DOI 10.1001/jamaneurol.2017.0469, PubMed 28586827
Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, Treutlein J, Degenhardt F, Forstner AJ, Heilmann-Heimbach S, Dietl L, Schwarze CE, Schendel D, Strohmaier J, Abdellaoui A, Adolfsson R, Air TM, Akil H, Alda M, Alliey-Rodriguez N, Andreassen OA, Babadjanova G, Bass NJ, Bauer M, Baune BT et al. (2017)
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
7 (6), e1155
DOI 10.1038/tp.2017.115, PubMed 28632202
Aas M, Melle I, Bettella F, Djurovic S, Le Hellard S, Bjella T, Ringen PA, Lagerberg TV, Smeland OB, Agartz I, Andreassen OA, Tesli M (2017)
Psychotic patients who used cannabis frequently before illness onset have higher genetic predisposition to schizophrenia than those who did not
48 (1), 43-49
DOI 10.1017/S0033291717001209, PubMed 28967348
Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M et al. (2016)
Novel genetic loci underlying human intracranial volume identified through genome-wide association
19 (12), 1569-1582
DOI 10.1038/nn.4398, PubMed 27694991
Athanasiu L, Giddaluru S, Fernandes C, Christoforou A, Reinvang I, Lundervold AJ, Nilsson LG, Kauppi K, Adolfsson R, Eriksson E, Sundet K, Djurovic S, Espeseth T, Nyberg L, Steen VM, Andreassen OA, Le Hellard S (2016)
A genetic association study of CSMD1 and CSMD2 with cognitive function
61, 209-216
DOI 10.1016/j.bbi.2016.11.026, PubMed 27890662
Falk A, Heine VM, Harwood AJ, Sullivan PF, Peitz M, Brustle O, Shen S, Sun YM, Glover JC, Posthuma D, Djurovic S (2016)
Modeling psychiatric disorders: from genomic findings to cellular phenotypes (vol 21, pg 1167, 2016)
Mol. Psychiatr., 21 (9), 1321
DOI 10.1038/mp.2016.100
Falk A, Heine VM, Harwood AJ, Sullivan PF, Peitz M, Brüstle O, Shen S, Sun YM, Glover JC, Posthuma D, Djurovic S (2016)
Modeling psychiatric disorders: from genomic findings to cellular phenotypes
21 (9), 1167-79
DOI 10.1038/mp.2016.89, PubMed 27240529
Gunnarsson B, Jónsdóttir GA, Björnsdóttir G, Konte B, Sulem P, Kristmundsdóttir S, Kehr B, Gústafsson Ó, Helgason H, Iordache PD, Ólafsson S, Frigge ML, Þorleifsson G, Arnarsdóttir S, Stefánsdóttir B, Giegling I, Djurovic S, Sundet KS, Espeseth T, Melle I, Hartmann AM, Thorsteinsdottir U, Kong A, Guðbjartsson DF, Ettinger U et al. (2016)
A sequence variant associating with educational attainment also affects childhood cognition
6, 36189
DOI 10.1038/srep36189, PubMed 27811963
Haram M, Bettella F, Brandt CL, Quintana DS, Nerhus M, Bjella T, Djurovic S, Westlye LT, Andreassen OA, Melle I, Tesli M (2016)
Contribution of oxytocin receptor polymorphisms to amygdala activation in schizophrenia spectrum disorders
2 (6), 353-358
DOI 10.1192/bjpo.bp.116.003376, PubMed 27847593
Johannessen J, Nærland T, Bloss C, Rietschel M, Strohmaier J, Gjevik E, Heiberg A, Djurovic S, Andreassen OA (2016)
Parents' attitudes toward genetic research in autism spectrum disorder
26 (2), 74-80
DOI 10.1097/YPG.0000000000000121, PubMed 26867185
Kaufmann T, Alnæs D, Brandt CL, Doan NT, Kauppi K, Bettella F, Lagerberg TV, Berg AO, Djurovic S, Agartz I, Melle IS, Ueland T, Andreassen OA, Westlye LT (2016)
Task modulations and clinical manifestations in the brain functional connectome in 1615 fMRI datasets
147, 243-252
DOI 10.1016/j.neuroimage.2016.11.073, PubMed 27916665
Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, Antaki D, Shetty A, Holmans PA, Pinto D, Gujral M, Brandler WM, Malhotra D, Wang Z, Fajarado KVF, Maile MS, Ripke S, Agartz I, Albus M, Alexander M, Amin F, Atkins J, Bacanu SA, Belliveau RA, Bergen SE et al. (2016)
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
49 (1), 27-35
DOI 10.1038/ng.3725, PubMed 27869829
Mehta D, Tropf FC, Gratten J, Bakshi A, Zhu Z, Bacanu SA, Hemani G, Magnusson PK, Barban N, Esko T, Metspalu A, Snieder H, Mowry BJ, Kendler KS, Yang J, Visscher PM, McGrath JJ, Mills MC, Wray NR, Lee SH, Schizophrenia Working Group of the Psychiatric Genomics Consortium, LifeLines Cohort Study, and TwinsUK, Andreassen OA, Bramon E, Bruggeman R, Buxbaum JD et al. (2016)
Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women
73 (5), 497-505
DOI 10.1001/jamapsychiatry.2016.0129, PubMed 27007234
Mäki-Marttunen T, Halnes G, Devor A, Witoelar A, Bettella F, Djurovic S, Wang Y, Einevoll GT, Andreassen OA, Dale AM (2016)
Functional Effects of Schizophrenia-Linked Genetic Variants on Intrinsic Single-Neuron Excitability: A Modeling Study
1 (1), 49-59
DOI 10.1016/j.bpsc.2015.09.002, PubMed 26949748
Mørch RH, Dieset I, Færden A, Hope S, Aas M, Nerhus M, Gardsjord ES, Joa I, Morken G, Agartz I, Aukrust P, Djurovic S, Melle I, Ueland T, Andreassen OA (2016)
Inflammatory evidence for the psychosis continuum model
67, 189-97
DOI 10.1016/j.psyneuen.2016.02.011, PubMed 26923849
Peng Q, Schork A, Bartsch H, Lo MT, Panizzon MS, Pediatric Imaging, Neurocognition and Genetics Study, Alzheimer’s Disease Neuroimaging Initiative, Westlye LT, Kremen WS, Jernigan TL, Le Hellard S, Steen VM, Espeseth T, Huentelman M, Håberg AK, Agartz I, Djurovic S, Andreassen OA, Dale AM, Schork NJ, Chen CH (2016)
Conservation of Distinct Genetically-Mediated Human Cortical Pattern
12 (7), e1006143
DOI 10.1371/journal.pgen.1006143, PubMed 27459196
Szabo A, Kovacs A, Riba J, Djurovic S, Rajnavolgyi E, Frecska E (2016)
The Endogenous Hallucinogen and Trace Amine N,N-Dimethyltryptamine (DMT) Displays Potent Protective Effects against Hypoxia via Sigma-1 Receptor Activation in Human Primary iPSC-Derived Cortical Neurons and Microglia-Like Immune Cells
10, 423
DOI 10.3389/fnins.2016.00423, PubMed 27683542
Tesli M, Wirgenes KV, Hughes T, Bettella F, Athanasiu L, Hoseth ES, Nerhus M, Lagerberg TV, Steen NE, Agartz I, Melle I, Dieset I, Djurovic S, Andreassen OA (2016)
VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls
209 (2), 114-20
DOI 10.1192/bjp.bp.115.161950, PubMed 26941264
Uhlirova H, Kılıç K, Tian P, Sakadžić S, Gagnon L, Thunemann M, Desjardins M, Saisan PA, Nizar K, Yaseen MA, Hagler DJ, Vandenberghe M, Djurovic S, Andreassen OA, Silva GA, Masliah E, Kleinfeld D, Vinogradov S, Buxton RB, Einevoll GT, Boas DA, Dale AM, Devor A (2016)
The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements
371 (1705)
DOI 10.1098/rstb.2015.0356, PubMed 27574309
Uhlirova H, Kılıç K, Tian P, Thunemann M, Desjardins M, Saisan PA, Sakadžić S, Ness TV, Mateo C, Cheng Q, Weldy KL, Razoux F, Vandenberghe M, Cremonesi JA, Ferri CG, Nizar K, Sridhar VB, Steed TC, Abashin M, Fainman Y, Masliah E, Djurovic S, Andreassen OA, Silva GA, Boas DA et al. (2016)
Cell type specificity of neurovascular coupling in cerebral cortex
5
DOI 10.7554/eLife.14315, PubMed 27244241
Wang Y, Bos SD, Harbo HF, Thompson WK, Schork AJ, Bettella F, Witoelar A, Lie BA, Li W, McEvoy LK, Djurovic S, Desikan RS, Dale AM, Andreassen OA (2016)
Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors
22 (14), 1783-1793
DOI 10.1177/1352458516635873, PubMed 26920376
Wang Y, Thompson WK, Schork AJ, Holland D, Chen CH, Bettella F, Desikan RS, Li W, Witoelar A, Zuber V, Devor A, Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium, Enhancing Neuro Imaging Genetics through Meta Analysis Consortium, Nöthen MM, Rietschel M, Chen Q, Werge T, Cichon S, Weinberger DR, Djurovic S, O'Donovan M, Visscher PM, Andreassen OA, Dale AM (2016)
Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS
12 (1), e1005803
DOI 10.1371/journal.pgen.1005803, PubMed 26808560
Zuber V, Marconett CN, Shi J, Hua X, Wheeler W, Yang C, Song L, Dale AM, Laplana M, Risch A, Witoelar A, Thompson WK, Schork AJ, Bettella F, Wang Y, Djurovic S, Zhou B, Borok Z, van der Heijden HF, de Graaf J, Swinkels D, Aben KK, McKay J, Hung RJ, Bikeböller H et al. (2016)
Pleiotropic Analysis of Lung Cancer and Blood Triglycerides
108 (12)
DOI 10.1093/jnci/djw167, PubMed 27565901
Aminoff SR, Tesli M, Bettella F, Aas M, Lagerberg TV, Djurovic S, Andreassen OA, Melle I (2015)
Polygenic risk scores in bipolar disorder subgroups
183, 310-4
DOI 10.1016/j.jad.2015.05.021, PubMed 26047958
Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM (2015)
Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
10 (4), e0123057
DOI 10.1371/journal.pone.0123057, PubMed 25853426
Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM (2015)
Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms
10 (5), e0128048
DOI 10.1371/journal.pone.0128048, PubMed 25978331
Andreassen OA, Thompson WK, Schork AJ, Ripke S, Mattingsdal M, Kelsoe JR, Kendler KS, O'Donovan MC, Rujescu D, Werge T, Sklar P, Psychiatric Genomics Consortium (PGC), Bipolar Disorder and Schizophrenia Working Groups, Roddey JC, Chen CH, McEvoy L, Desikan RS, Djurovic S, Dale AM (2015)
Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate
11 (11), e1005544
DOI 10.1371/journal.pgen.1005544, PubMed 26540268
Athanasiu L, Smorr LL, Tesli M, Røssberg JI, Sønderby IE, Spigset O, Djurovic S, Andreassen OA (2015)
Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs
29 (8), 884-91
DOI 10.1177/0269881115584469, PubMed 25944848
Chen CH, Peng Q, Schork AJ, Lo MT, Fan CC, Wang Y, Desikan RS, Bettella F, Hagler DJ, Pediatric Imaging, Neurocognition and Genetics Study, Alzheimer’s Disease Neuroimaging Initiative, Westlye LT, Kremen WS, Jernigan TL, Le Hellard S, Steen VM, Espeseth T, Huentelman M, Håberg AK, Agartz I, Djurovic S, Andreassen OA, Schork N, Dale AM, Pediatric Imaging Neurocognition and Genetics Study et al. (2015)
Large-scale genomics unveil polygenic architecture of human cortical surface area
6, 7549
DOI 10.1038/ncomms8549, PubMed 26189703
Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, Chasman DI, McEvoy LK, Holland D, Chen CH, Karow DS, Brewer JB, Hess CP, Williams J, Sims R, O'Donovan MC, Choi SH, Bis JC, Ikram MA, Gudnason V, DeStefano AL, van der Lee SJ, Psaty BM, van Duijn CM, Launer L et al. (2015)
Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease
131 (23), 2061-2069
DOI 10.1161/CIRCULATIONAHA.115.015489, PubMed 25862742
Desikan RS, Schork AJ, Wang Y, Witoelar A, Sharma M, McEvoy LK, Holland D, Brewer JB, Chen CH, Thompson WK, Harold D, Williams J, Owen MJ, O'Donovan MC, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Schellenberg GD, Heutink P, Singleton AB, Brice A, Wood NW, Hardy J, Martinez M et al. (2015)
Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus
20 (12), 1588-95
DOI 10.1038/mp.2015.6, PubMed 25687773
Goulart LF, Bettella F, Sønderby IE, Schork AJ, Thompson WK, Mattingsdal M, Steen VM, Zuber V, Wang Y, Dale AM, PRACTICAL/ELLIPSE consortium, Andreassen OA, Djurovic S (2015)
MicroRNAs enrichment in GWAS of complex human phenotypes
16 (1), 304
DOI 10.1186/s12864-015-1513-5, PubMed 25884492
Haram M, Tesli M, Bettella F, Djurovic S, Andreassen OA, Melle I (2015)
Association between Genetic Variation in the Oxytocin Receptor Gene and Emotional Withdrawal, but not between Oxytocin Pathway Genes and Diagnosis in Psychotic Disorders
9, 9
DOI 10.3389/fnhum.2015.00009, PubMed 25667571
Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivières S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, Bralten J, Brown AA, Chakravarty MM, Chen Q, Ching CR, Cuellar-Partida G, den Braber A, Giddaluru S, Goldman AL, Grimm O et al. (2015)
Common genetic variants influence human subcortical brain structures
520 (7546), 224-9
DOI 10.1038/nature14101, PubMed 25607358
Hoeffding LK, Duong LT, Ingason A, Rosengren A, Sorbanski E, Witt SH, Djurovic S, Andreassen OA, Hansen T, Werge T, Rasmussen HB (2015)
Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders
70 (4), 276-9
DOI 10.3109/08039488.2015.1095944, PubMed 26559242
Hope S, Hoseth E, Dieset I, Mørch RH, Aas M, Aukrust P, Djurovic S, Melle I, Ueland T, Agartz I, Ueland T, Westlye LT, Andreassen OA (2015)
Inflammatory markers are associated with general cognitive abilities in schizophrenia and bipolar disorder patients and healthy controls
165 (2-3), 188-94
DOI 10.1016/j.schres.2015.04.004, PubMed 25956633
Howrigan DP, Simonson MA, Davies G, Harris SE, Tenesa A, Starr JM, Liewald DC, Deary IJ, McRae A, Wright MJ, Montgomery GW, Hansell N, Martin NG, Payton A, Horan M, Ollier WE, Abdellaoui A, Boomsma DI, DeRosse P, Knowles EE, Glahn DC, Djurovic S, Melle I, Andreassen OA, Christoforou A et al. (2015)
Genome-wide autozygosity is associated with lower general cognitive ability
21 (6), 837-43
DOI 10.1038/mp.2015.120, PubMed 26390830
Hughes T, Hansson L, Sønderby IE, Athanasiu L, Zuber V, Tesli M, Song J, Hultman CM, Bergen SE, Landén M, Melle I, Andreassen OA, Djurovic S (2015)
A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia
80 (4), 323-330
DOI 10.1016/j.biopsych.2015.09.021, PubMed 26682468
Johansson MM, Van Geystelen A, Larmuseau MH, Djurovic S, Andreassen OA, Agartz I, Jazin E (2015)
Microarray Analysis of Copy Number Variants on the Human Y Chromosome Reveals Novel and Frequent Duplications Overrepresented in Specific Haplogroups
10 (8), e0137223
DOI 10.1371/journal.pone.0137223, PubMed 26322892
LeBlanc M, Zuber V, Andreassen BK, Witoelar A, Zeng L, Bettella F, Wang Y, McEvoy LK, Thompson WK, Schork AJ, Reppe S, Barrett-Connor E, Ligthart S, Dehghan A, Gautvik KM, Nelson CP, Schunkert H, Samani NJ, CARDIoGRAM Consortium, Ridker PM, Chasman DI, Aukrust P, Djurovic S, Frigessi A, Desikan RS et al. (2015)
Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors
118 (1), 83-94
DOI 10.1161/CIRCRESAHA.115.306629, PubMed 26487741
Lee SH, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AA, Ripke S, Andreassen OA, Frisell T, Gusev A, Hu X, Karlsson R, Mantzioris VX, McGrath JJ, Mehta D, Stahl EA, Zhao Q, Kendler KS, Sullivan PF, Price AL, O'Donovan M, Okada Y, Mowry BJ, Raychaudhuri S, Wray NR, Schizophrenia Working Group of the Psychiatric Genomics Consortium and Rheumatoid Arthritis Consortium International et al. (2015)
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis
44 (5), 1706-21
DOI 10.1093/ije/dyv136, PubMed 26286434
Mellerup E, Andreassen OA, Bennike B, Dam H, Djurovic S, Hansen T, Jorgensen MB, Kessing LV, Koefoed P, Melle I, Mors O, Werge T, Moeller GL (2015)
Combinations of Genetic Data Present in Bipolar Patients, but Absent in Control Persons
10 (11), e0143432
DOI 10.1371/journal.pone.0143432, PubMed 26587987
Reppe S, Wang Y, Thompson WK, McEvoy LK, Schork AJ, Zuber V, LeBlanc M, Bettella F, Mills IG, Desikan RS, Djurovic S, Gautvik KM, Dale AM, Andreassen OA, GEFOS Consortium (2015)
Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci
10 (12), e0144531
DOI 10.1371/journal.pone.0144531, PubMed 26695485
Srinivasan S, Bettella F, Mattingsdal M, Wang Y, Witoelar A, Schork AJ, Thompson WK, Zuber V, Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, Winsvold BS, Zwart JA, Collier DA, Desikan RS, Melle I, Werge T, Dale AM, Djurovic S, Andreassen OA (2015)
Genetic Markers of Human Evolution Are Enriched in Schizophrenia
80 (4), 284-292
DOI 10.1016/j.biopsych.2015.10.009, PubMed 26681495
Steinberg S, Stefansson H, Jonsson T, Johannsdottir H, Ingason A, Helgason H, Sulem P, Magnusson OT, Gudjonsson SA, Unnsteinsdottir U, Kong A, Helisalmi S, Soininen H, Lah JJ, DemGene, Aarsland D, Fladby T, Ulstein ID, Djurovic S, Sando SB, White LR, Knudsen GP, Westlye LT, Selbæk G, Giegling I et al. (2015)
Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease
47 (5), 445-7
DOI 10.1038/ng.3246, PubMed 25807283
Tesli M, Kauppi K, Bettella F, Brandt CL, Kaufmann T, Espeseth T, Mattingsdal M, Agartz I, Melle I, Djurovic S, Westlye LT, Andreassen OA (2015)
Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder
10 (7), e0134202
DOI 10.1371/journal.pone.0134202, PubMed 26222050
Trampush JW, Lencz T, Knowles E, Davies G, Guha S, Pe'er I, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, Mukherjee S, DeRosse P, Lundervold A, Steen VM, John M, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B et al. (2015)
Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment
168B (5), 363-73
DOI 10.1002/ajmg.b.32319, PubMed 25951819
Zayats T, Athanasiu L, Sonderby I, Djurovic S, Westlye LT, Tamnes CK, Fladby T, Aase H, Zeiner P, Reichborn-Kjennerud T, Knappskog PM, Knudsen GP, Andreassen OA, Johansson S, Haavik J (2015)
Genome-wide analysis of attention deficit hyperactivity disorder in Norway
10 (4), e0122501
DOI 10.1371/journal.pone.0122501, PubMed 25875332
Andreassen OA, Harbo HF, Wang Y, Thompson WK, Schork AJ, Mattingsdal M, Zuber V, Bettella F, Ripke S, Kelsoe JR, Kendler KS, O'Donovan MC, Sklar P, Psychiatric Genomics Consortium (PGC) Bipolar Disorder and Schizophrenia Work Groups, International Multiple Sclerosis Genetics Consortium (IMSGC), McEvoy LK, Desikan RS, Lie BA, Djurovic S, Dale AM (2014)
Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci
20 (2), 207-14
DOI 10.1038/mp.2013.195, PubMed 24468824
Andreassen OA, McEvoy LK, Thompson WK, Wang Y, Reppe S, Schork AJ, Zuber V, Barrett-Connor E, Gautvik K, Aukrust P, Karlsen TH, Djurovic S, Desikan RS, Dale AM, International Consortium for Blood Pressure Genome-Wide Association Studies, Genetic Factors for Osteoporosis Consortium (2014)
Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes
63 (4), 819-26
DOI 10.1161/HYPERTENSIONAHA.113.02077, PubMed 24396023
Andreassen OA, Zuber V, Thompson WK, Schork AJ, Bettella F, PRACTICAL Consortium, CRUK GWAS, Djurovic S, Desikan RS, Mills IG, Dale AM (2014)
Shared common variants in prostate cancer and blood lipids
43 (4), 1205-14
DOI 10.1093/ije/dyu090, PubMed 24786909
Christoforou A, Espeseth T, Davies G, Fernandes CPD, Giddaluru S, Mattheisen M, Tenesa A, Harris SE, Liewald DC, Payton A, Ollier W, Horan M, Pendleton N, Haggarty P, Djurovic S, Herms S, Hoffman P, Cichon S, Starr JM, Lundervold A, Reinvang I, Steen VM, Deary IJ, Le Hellard S (2014)
GWAS-based pathway analysis differentiates between fluid and crystallized intelligence
Genes Brain Behav., 13 (7), 663-674
DOI 10.1111/gbb.12152
Dieset I, Haukvik UK, Melle I, Røssberg JI, Ueland T, Hope S, Dale AM, Djurovic S, Aukrust P, Agartz I, Andreassen OA (2014)
Association between altered brain morphology and elevated peripheral endothelial markers--implications for psychotic disorders
161 (2-3), 222-8
DOI 10.1016/j.schres.2014.11.006, PubMed 25433965
Haram M, Tesli M, Dieset I, Steen NE, Røssberg JI, Djurovic S, Andreassen OA, Melle I (2014)
An attempt to identify single nucleotide polymorphisms contributing to possible relationships between personality traits and oxytocin-related genes
69 (1), 25-30
DOI 10.1159/000356965, PubMed 24458227
Kauppi K, Westlye LT, Tesli M, Bettella F, Brandt CL, Mattingsdal M, Ueland T, Espeseth T, Agartz I, Melle I, Djurovic S, Andreassen OA (2014)
Polygenic risk for schizophrenia associated with working memory-related prefrontal brain activation in patients with schizophrenia and healthy controls
41 (3), 736-43
DOI 10.1093/schbul/sbu152, PubMed 25392519
Tesli M, Espeseth T, Bettella F, Mattingsdal M, Aas M, Melle I, Djurovic S, Andreassen OA (2014)
Polygenic risk score and the psychosis continuum model
130 (4), 311-7
DOI 10.1111/acps.12307, PubMed 24961959
Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, Almasy L, Almeida J, Alpert K, Andreasen NC, Andreassen OA, Apostolova LG, Appel K, Armstrong NJ, Aribisala B, Bastin ME et al. (2014)
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
8 (2), 153-82
DOI 10.1007/s11682-013-9269-5, PubMed 24399358
Wirgenes KV, Tesli M, Inderhaug E, Athanasiu L, Agartz I, Melle I, Hughes T, Andreassen OA, Djurovic S (2014)
ANK3 gene expression in bipolar disorder and schizophrenia
205 (3), 244-5
DOI 10.1192/bjp.bp.114.145433, PubMed 24809399
Zai CC, Manchia M, Sønderby IE, Yilmaz Z, De Luca V, Tiwari AK, Squassina A, Zai GC, Shaikh SA, Strauss J, King N, Le Foll B, Kaplan AS, Finseth PI, Vaaler AE, Djurovic S, Andreassen OA, Vincent JB, Kennedy JL (2014)
Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders
16 (3), 171-9
DOI 10.3109/15622975.2014.953011, PubMed 25264289
Aas M, Haukvik UK, Djurovic S, Tesli M, Athanasiu L, Bjella T, Hansson L, Cattaneo A, Agartz I, Andreassen OA, Melle I (2014)
Interplay between childhood trauma and BDNF val66met variants on blood BDNF mRNA levels and on hippocampus subfields volumes in schizophrenia spectrum and bipolar disorders
59, 14-21
DOI 10.1016/j.jpsychires.2014.08.011, PubMed 25246365
Aberg KA, Liu Y, Bukszár J, McClay JL, Khachane AN, Andreassen OA, Blackwood D, Corvin A, Djurovic S, Gurling H, Ophoff R, Pato CN, Pato MT, Riley B, Webb T, Kendler K, O'Donovan M, Craddock N, Kirov G, Owen M, Rujescu D, St Clair D, Werge T, Hultman CM, Delisi LE et al. (2013)
A comprehensive family-based replication study of schizophrenia genes
70 (6), 573-81
DOI 10.1001/jamapsychiatry.2013.288, PubMed 23894747
Andreassen OA, Djurovic S, Thompson WK, Schork AJ, Kendler KS, O'Donovan MC, Rujescu D, Werge T, van de Bunt M, Morris AP, McCarthy MI, International Consortium for Blood Pressure GWAS, Diabetes Genetics Replication and Meta-analysis Consortium, Psychiatric Genomics Consortium Schizophrenia Working Group, Roddey JC, McEvoy LK, Desikan RS, Dale AM (2013)
Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors
92 (2), 197-209
DOI 10.1016/j.ajhg.2013.01.001, PubMed 23375658
Andreassen OA, Thompson WK, Schork AJ, Ripke S, Mattingsdal M, Kelsoe JR, Kendler KS, O'Donovan MC, Rujescu D, Werge T, Sklar P, Psychiatric Genomics Consortium (PGC), Bipolar Disorder and Schizophrenia Working Groups, Roddey JC, Chen CH, McEvoy L, Desikan RS, Djurovic S, Dale AM (2013)
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate
9 (4), e1003455
DOI 10.1371/journal.pgen.1003455, PubMed 23637625
Bergmann O, Haukvik UK, Brown AA, Rimol LM, Hartberg CB, Athanasiu L, Melle I, Djurovic S, Andreassen OA, Dale AM, Agartz I (2013)
ZNF804A and cortical thickness in schizophrenia and bipolar disorder
212 (2), 154-7
DOI 10.1016/j.pscychresns.2013.01.007, PubMed 23562677
Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, Andreassen OA, Anjorin A, Anney R, Anttila V, Arking DE, Asherson P, Azevedo MH, Backlund L, Badner JA, Bailey AJ et al. (2013)
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
45 (9), 984-94
DOI 10.1038/ng.2711, PubMed 23933821
Fernandes CP, Christoforou A, Giddaluru S, Ersland KM, Djurovic S, Mattheisen M, Lundervold AJ, Reinvang I, Nöthen MM, Rietschel M, Ophoff RA, Genetic Risk and Outcome of Psychosis (GROUP), Hofman A, Uitterlinden AG, Werge T, Cichon S, Espeseth T, Andreassen OA, Steen VM, Le Hellard S (2013)
A genetic deconstruction of neurocognitive traits in schizophrenia and bipolar disorder
8 (12), e81052
DOI 10.1371/journal.pone.0081052, PubMed 24349030
Finseth PI, Sønderby IE, Djurovic S, Agartz I, Malt UF, Melle I, Morken G, Andreassen OA, Vaaler AE, Tesli M (2013)
Association analysis between suicidal behaviour and candidate genes of bipolar disorder and schizophrenia
163, 110-4
DOI 10.1016/j.jad.2013.12.018, PubMed 24461634
Hibar DP, Medland SE, Stein JL, Kim S, Shen L, Saykin AJ, de Zubicaray GI, McMahon KL, Montgomery GW, Martin NG, Wright MJ, Djurovic S, Agartz IA, Andreassen OA, Thompson PM (2013)
Genetic clustering on the hippocampal surface for genome-wide association studies
16 (Pt 2), 690-7
DOI 10.1007/978-3-642-40763-5_85, PubMed 24579201
Hibar DP, Medland SE, Stein JL, Kim S, Shen L, Saykin AJ, de Zubicaray GI, McMahon KL, Montgomery GW, Martin NG, Wright MJ, Djurovic S, Agartz IA, Andreassen OA, Thompson PM (2013)
Genetic Clustering on the Hippocampal Surface for Genome-Wide Association Studies
LECT NOTES COMPUT SC, 8150, 690-697
Lencz T, Knowles E, Davies G, Guha S, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, Mukherjee S, DeRosse P, Lundervold A, Steen VM, John M, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Ikeda M, Roussos P et al. (2013)
Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT)
19 (2), 168-74
DOI 10.1038/mp.2013.166, PubMed 24342994
Ruderfer DM, Fanous AH, Ripke S, McQuillin A, Amdur RL, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Gejman PV, O'Donovan MC, Andreassen OA, Djurovic S, Hultman CM, Kelsoe JR, Jamain S, Landén M, Leboyer M, Nimgaonkar V, Nurnberger J, Smoller JW, Craddock N, Corvin A, Sullivan PF, Holmans P, Sklar P et al. (2013)
Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia
19 (9), 1017-1024
DOI 10.1038/mp.2013.138, PubMed 24280982
Tesli M, Egeland R, Sønderby IE, Haukvik UK, Bettella F, Hibar DP, Thompson PM, Rimol LM, Melle I, Agartz I, Djurovic S, Andreassen OA (2013)
No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes
151 (1), 291-7
DOI 10.1016/j.jad.2013.06.008, PubMed 23820096
Tesli M, Skatun KC, Ousdal OT, Brown AA, Thoresen C, Agartz I, Melle I, Djurovic S, Jensen J, Andreassen OA (2013)
CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls
8 (2), e56970
DOI 10.1371/journal.pone.0056970, PubMed 23437284
Aas M, Haukvik UK, Djurovic S, Bergmann Ø, Athanasiu L, Tesli MS, Hellvin T, Steen NE, Agartz I, Lorentzen S, Sundet K, Andreassen OA, Melle I (2013)
BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses
46, 181-8
DOI 10.1016/j.pnpbp.2013.07.008, PubMed 23876786
Athanasiu L, Brown AA, Birkenaes AB, Mattingsdal M, Agartz I, Melle I, Steen VM, Andreassen OA, Djurovic S (2012)
Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study
197 (3), 327-36
DOI 10.1016/j.psychres.2011.12.036, PubMed 22417934
Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM, Alzheimer's Disease Neuroimaging Initiative et al. (2012)
Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans
109 (10), 3985-90
DOI 10.1073/pnas.1105829109, PubMed 22343285
Brown AA, Jensen J, Nikolova YS, Djurovic S, Agartz I, Server A, Ferrell RE, Manuck SB, Mattingsdal M, Melle I, Hariri AR, Frigessi A, Andreassen OA (2012)
Genetic variants affecting the neural processing of human facial expressions: evidence using a genome-wide functional imaging approach
2 (7), e143
DOI 10.1038/tp.2012.67, PubMed 22828495
Christoforou A, Dondrup M, Mattingsdal M, Mattheisen M, Giddaluru S, Nöthen MM, Rietschel M, Cichon S, Djurovic S, Andreassen OA, Jonassen I, Steen VM, Puntervoll P, Le Hellard S (2012)
Linkage-disequilibrium-based binning affects the interpretation of GWASs
90 (4), 727-33
DOI 10.1016/j.ajhg.2012.02.025, PubMed 22444669
Dieset I, Djurovic S, Tesli M, Hope S, Mattingsdal M, Michelsen A, Joa I, Larsen TK, Agartz I, Melle I, Røssberg JI, Aukrust P, Andreassen OA, Ueland T (2012)
Up-regulation of NOTCH4 gene expression in bipolar disorder
169 (12), 1292-300
DOI 10.1176/appi.ajp.2012.11091431, PubMed 23212060
Ersland KM, Christoforou A, Stansberg C, Espeseth T, Mattheisen M, Mattingsdal M, Hardarson GA, Hansen T, Fernandes CP, Giddaluru S, Breuer R, Strohmaier J, Djurovic S, Nöthen MM, Rietschel M, Lundervold AJ, Werge T, Cichon S, Andreassen OA, Reinvang I, Steen VM, Le Hellard S (2012)
Gene-based analysis of regionally enriched cortical genes in GWAS data sets of cognitive traits and psychiatric disorders
7 (2), e31687
DOI 10.1371/journal.pone.0031687, PubMed 22384057
Håvik B, Degenhardt FA, Johansson S, Fernandes CP, Hinney A, Scherag A, Lybæk H, Djurovic S, Christoforou A, Ersland KM, Giddaluru S, O'Donovan MC, Owen MJ, Craddock N, Mühleisen TW, Mattheisen M, Schimmelmann BG, Renner T, Warnke A, Herpertz-Dahlmann B, Sinzig J, Albayrak Ö, Rietschel M, Nöthen MM, Bramham CR et al. (2012)
DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder
7 (4), e35424
DOI 10.1371/journal.pone.0035424, PubMed 22539971
Jonsson T, Stefansson H, Steinberg S, Jonsdottir I, Jonsson PV, Snaedal J, Bjornsson S, Huttenlocher J, Levey AI, Lah JJ, Rujescu D, Hampel H, Giegling I, Andreassen OA, Engedal K, Ulstein I, Djurovic S, Ibrahim-Verbaas C, Hofman A, Ikram MA, van Duijn CM, Thorsteinsdottir U, Kong A, Stefansson K (2012)
Variant of TREM2 associated with the risk of Alzheimer's disease
368 (2), 107-16
DOI 10.1056/NEJMoa1211103, PubMed 23150908
Jönsson EG, Saetre P, Nyholm H, Djurovic S, Melle I, Andreassen OA, Skjødt C, Thygesen JH, Werge T, Hall H, Agartz I, Terenius L (2012)
Lack of association between the regulator of G-protein signaling 4 (RGS4) rs951436 polymorphism and schizophrenia
22 (5), 263-4
DOI 10.1097/YPG.0b013e32834f3558, PubMed 22157635
Kähler AK, Rimol LM, Brown AA, Djurovic S, Hartberg CB, Melle I, Dale AM, Andreassen OA, Agartz I (2012)
Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis
159B (6), 722-30
DOI 10.1002/ajmg.b.32076, PubMed 22815203
Lindholm Carlström E, Saetre P, Rosengren A, Thygesen JH, Djurovic S, Melle I, Andreassen OA, Werge T, Agartz I, Hall H, Terenius L, Jönsson EG (2012)
Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
8, 24
DOI 10.1186/1744-9081-8-24, PubMed 22594806
Mattingsdal M, Brown AA, Djurovic S, Sønderby IE, Server A, Melle I, Agartz I, Hovig E, Jensen J, Andreassen OA (2012)
Pathway analysis of genetic markers associated with a functional MRI faces paradigm implicates polymorphisms in calcium responsive pathways
70, 143-9
DOI 10.1016/j.neuroimage.2012.12.035, PubMed 23274185
Ousdal OT, Anand Brown A, Jensen J, Nakstad PH, Melle I, Agartz I, Djurovic S, Bogdan R, Hariri AR, Andreassen OA (2012)
Associations between variants near a monoaminergic pathways gene (PHOX2B) and amygdala reactivity: a genome-wide functional imaging study
15 (3), 273-85
DOI 10.1017/thg.2012.5, PubMed 22856363
Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS et al. (2012)
Identification of common variants associated with human hippocampal and intracranial volumes
44 (5), 552-61
DOI 10.1038/ng.2250, PubMed 22504417
Steinberg S, de Jong S, Mattheisen M, Costas J, Demontis D, Jamain S, Pietiläinen OP, Lin K, Papiol S, Huttenlocher J, Sigurdsson E, Vassos E, Giegling I, Breuer R, Fraser G, Walker N, Melle I, Djurovic S, Agartz I, Tuulio-Henriksson A, Suvisaari J, Lönnqvist J, Paunio T, Olsen L, Hansen T et al. (2012)
Common variant at 16p11.2 conferring risk of psychosis
19 (1), 108-14
DOI 10.1038/mp.2012.157, PubMed 23164818
Vassos E, Steinberg S, Cichon S, Breen G, Sigurdsson E, Andreassen OA, Djurovic S, Morken G, Grigoroiu-Serbanescu M, Diaconu CC, Czerski PM, Hauser J, Babadjanova G, Abramova LI, Mühleisen TW, Nöthen MM, Rietschel M, McGuffin P, St Clair D, Gustafsson O, Melle I, Pietiläinen OP, Ruggeri M, Tosato S, Werge T et al. (2012)
Replication study and meta-analysis in European samples supports association of the 3p21.1 locus with bipolar disorder
72 (8), 645-50
DOI 10.1016/j.biopsych.2012.02.040, PubMed 22560537
Wirgenes KV, Sønderby IE, Haukvik UK, Mattingsdal M, Tesli M, Athanasiu L, Sundet K, Røssberg JI, Dale AM, Brown AA, Agartz I, Melle I, Djurovic S, Andreassen OA (2012)
TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders
2 (5), e112
DOI 10.1038/tp.2012.39, PubMed 22832956
Agartz I, Brown AA, Rimol LM, Hartberg CB, Dale AM, Melle I, Djurovic S, Andreassen OA (2011)
Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia
70 (7), 696-8
DOI 10.1016/j.biopsych.2011.02.034, PubMed 21514568
Bakken TE, Bloss CS, Roddey JC, Joyner AH, Rimol LM, Djurovic S, Melle I, Sundet K, Agartz I, Andreassen OA, Dale AM, Schork NJ (2011)
Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia
68 (8), 781-90
DOI 10.1001/archgenpsychiatry.2011.81, PubMed 21810643
Caprini S, Saetre P, Melle I, Djurovic S, Andreassen OA, Skjødt C, Duong L, Werge T, Hall H, Agartz I, Terenius L, Jönsson EG (2011)
Lack of association between two dopamine D2 receptor gene polymorphisms and schizophrenia
21 (4), 214-5
DOI 10.1097/YPG.0b013e328341e020, PubMed 21712758
Cichon S, Muehleisen TW, Degenhardt FA, Mattheisen M, Miro X, Strohmaier J, Steffens M, Meesters C, Herms S, Weingarten M, Priebe L, Haenisch B, Alexander M, Vollmer J, Breuer R, Schmal C, Tessmann P, Moebus S, Wichmann HE, Schreiber S, Muller-Myhsok B, Lucae S, Jamain S, Leboyer M, Bellivier F et al. (2011)
Genome-wide Association Study Identifies Genetic Variation in Neurocan as a Susceptibility Factor for Bipolar Disorder (vol 88, pg 372, 2011)
Am. J. Hum. Genet., 88 (3), 396
DOI 10.1016/j.ajhg.2011.03.001
Cichon S, Mühleisen TW, Degenhardt FA, Mattheisen M, Miró X, Strohmaier J, Steffens M, Meesters C, Herms S, Weingarten M, Priebe L, Haenisch B, Alexander M, Vollmer J, Breuer R, Schmäl C, Tessmann P, Moebus S, Wichmann HE, Schreiber S, Müller-Myhsok B, Lucae S, Jamain S, Leboyer M, Bellivier F et al. (2011)
Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder
88 (3), 372-81
DOI 10.1016/j.ajhg.2011.01.017, PubMed 21353194
Finsen AV, Lunde IG, Sjaastad I, Østli EK, Lyngra M, Jarstadmarken HO, Hasic A, Nygård S, Wilcox-Adelman SA, Goetinck PF, Lyberg T, Skrbic B, Florholmen G, Tønnessen T, Louch WE, Djurovic S, Carlson CR, Christensen G (2011)
Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway
6 (12), e28302
DOI 10.1371/journal.pone.0028302, PubMed 22164265
Hansen T, Ingason A, Djurovic S, Melle I, Fenger M, Gustafsson O, Jakobsen KD, Rasmussen HB, Tosato S, Rietschel M, Frank J, Owen M, Bonetto C, Suvisaari J, Thygesen JH, Pétursson H, Lönnqvist J, Sigurdsson E, Giegling I, Craddock N, O'Donovan MC, Ruggeri M, Cichon S, Ophoff RA, Pietiläinen O et al. (2011)
At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia
70 (1), 59-63
DOI 10.1016/j.biopsych.2011.01.031, PubMed 21414605
Håvik B, Le Hellard S, Rietschel M, Lybæk H, Djurovic S, Mattheisen M, Mühleisen TW, Degenhardt F, Priebe L, Maier W, Breuer R, Schulze TG, Agartz I, Melle I, Hansen T, Bramham CR, Nöthen MM, Stevens B, Werge T, Andreassen OA, Cichon S, Steen VM (2011)
The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia
70 (1), 35-42
DOI 10.1016/j.biopsych.2011.01.030, PubMed 21439553
Ingason A, Kirov G, Giegling I, Hansen T, Isles AR, Jakobsen KD, Kristinsson KT, le Roux L, Gustafsson O, Craddock N, Möller HJ, McQuillin A, Muglia P, Cichon S, Rietschel M, Ophoff RA, Djurovic S, Andreassen OA, Pietiläinen OP, Peltonen L, Dempster E, Collier DA, St Clair D, Rasmussen HB, Glenthøj BY et al. (2011)
Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness
168 (4), 408-17
DOI 10.1176/appi.ajp.2010.09111660, PubMed 21324950
Koefoed P, Andreassen OA, Bennike B, Dam H, Djurovic S, Hansen T, Jorgensen MB, Kessing LV, Melle I, Møller GL, Mors O, Werge T, Mellerup E (2011)
Combinations of SNPs related to signal transduction in bipolar disorder
6 (8), e23812
DOI 10.1371/journal.pone.0023812, PubMed 21897858
LeBlanc M, Kulle B, Sundet K, Agartz I, Melle I, Djurovic S, Frigessi A, Andreassen OA (2011)
Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function
46 (2), 271-8
DOI 10.1016/j.jpsychires.2011.11.001, PubMed 22126837
Olsen L, Hansen T, Djurovic S, Haastrup E, Albrecthsen A, Hoeffding LK, Secher A, Gustafsson O, Jakobsen KD, Nielsen FC, Ullum H, Morken G, Agartz I, Melle I, Gether U, Andreassen OA, Werge T (2011)
Copy number variations in affective disorders and meta-analysis
21 (6), 319-22
DOI 10.1097/YPG.0b013e3283463deb, PubMed 21451435
Pers TH, Hansen NT, Lage K, Koefoed P, Dworzynski P, Miller ML, Flint TJ, Mellerup E, Dam H, Andreassen OA, Djurovic S, Melle I, Børglum AD, Werge T, Purcell S, Ferreira MA, Kouskoumvekaki I, Workman CT, Hansen T, Mors O, Brunak S (2011)
Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes
35 (5), 318-32
DOI 10.1002/gepi.20580, PubMed 21484861
Steinberg S, de Jong S, Irish Schizophrenia Genomics Consortium, Andreassen OA, Werge T, Børglum AD, Mors O, Mortensen PB, Gustafsson O, Costas J, Pietiläinen OP, Demontis D, Papiol S, Huttenlocher J, Mattheisen M, Breuer R, Vassos E, Giegling I, Fraser G, Walker N, Tuulio-Henriksson A, Suvisaari J, Lönnqvist J, Paunio T, Agartz I et al. (2011)
Common variants at VRK2 and TCF4 conferring risk of schizophrenia
20 (20), 4076-81
DOI 10.1093/hmg/ddr325, PubMed 21791550
Tesli M, Koefoed P, Athanasiu L, Mattingsdal M, Gustafsson O, Agartz I, Rimol LM, Brown A, Wirgenes KV, Smorr LL, Kähler AK, Werge T, Mors O, Mellerup E, Jönsson EG, Melle I, Morken G, Djurovic S, Andreassen OA (2011)
Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples
156B (8), 969-74
DOI 10.1002/ajmg.b.31244, PubMed 21972176
Van Schijndel JE, Van Zweeden M, Van Loo KM, Djurovic S, Andreassen OA, Hansen T, Werge T, Nyegaard M, Sørensen KM, Nordentoft M, Mortensen PB, Mors O, Børglum AD, Del-Favero J, Norrback KF, Adolfsson R, De Hert M, Claes S, Cichon S, Rietschel M, Nöthen MM, Kallunki P, Pedersen JT, Martens GJ (2011)
Dual association of a TRKA polymorphism with schizophrenia
21 (3), 125-31
DOI 10.1097/YPG.0b013e3283437194, PubMed 21317683
Aas M, Djurovic S, Athanasiu L, Steen NE, Agartz I, Lorentzen S, Sundet K, Andreassen OA, Melle I (2011)
Serotonin transporter gene polymorphism, childhood trauma, and cognition in patients with psychotic disorders
38 (1), 15-22
DOI 10.1093/schbul/sbr113, PubMed 21908796
Athanasiu L, Mattingsdal M, Kähler AK, Brown A, Gustafsson O, Agartz I, Giegling I, Muglia P, Cichon S, Rietschel M, Pietiläinen OP, Peltonen L, Bramon E, Collier D, Clair DS, Sigurdsson E, Petursson H, Rujescu D, Melle I, Steen VM, Djurovic S, Andreassen OA (2010)
Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
44 (12), 748-53
DOI 10.1016/j.jpsychires.2010.02.002, PubMed 20185149
Athanasiu L, Mattingsdal M, Melle I, Inderhaug E, Lien T, Agartz I, Lorentzen S, Morken G, Andreassen OA, Djurovic S (2010)
Intron 12 in NTRK3 is associated with bipolar disorder
185 (3), 358-62
DOI 10.1016/j.psychres.2010.05.011, PubMed 20554328
Chen X, Lee G, Maher BS, Fanous AH, Chen J, Zhao Z, Guo A, van den Oord E, Sullivan PF, Shi J, Levinson DF, Gejman PV, Sanders A, Duan J, Owen MJ, Craddock NJ, O'Donovan MC, Blackman J, Lewis D, Kirov GK, Qin W, Schwab S, Wildenauer D, Chowdari K, Nimgaonkar V et al. (2010)
GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia
16 (11), 1117-29
DOI 10.1038/mp.2010.96, PubMed 20838396
Djurovic S, Gustafsson O, Mattingsdal M, Athanasiu L, Bjella T, Tesli M, Agartz I, Lorentzen S, Melle I, Morken G, Andreassen OA (2010)
A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample
126 (1-2), 312-6
DOI 10.1016/j.jad.2010.04.007, PubMed 20451256
Holtze M, Saetre P, Erhardt S, Schwieler L, Werge T, Hansen T, Nielsen J, Djurovic S, Melle I, Andreassen OA, Hall H, Terenius L, Agartz I, Engberg G, Jönsson EG, Schalling M (2010)
Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: an association study
127 (1-3), 270-2
DOI 10.1016/j.schres.2010.10.002, PubMed 21030213
Hope S, Melle I, Aukrust P, Agartz I, Lorentzen S, Steen NE, Djurovic S, Ueland T, Andreassen OA (2010)
Osteoprotegerin levels in patients with severe mental disorders
35 (5), 304-10
DOI 10.1503/jpn.090088, PubMed 20569643
Ingason A, Giegling I, Cichon S, Hansen T, Rasmussen HB, Nielsen J, Jürgens G, Muglia P, Hartmann AM, Strengman E, Vasilescu C, Mühleisen TW, Djurovic S, Melle I, Lerer B, Möller HJ, Francks C, Pietiläinen OP, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Walshe M, Vassos E, Di Forti M, Murray R et al. (2010)
A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia
19 (7), 1379-86
DOI 10.1093/hmg/ddq009, PubMed 20071346
Kähler AK, Djurovic S, Rimol LM, Brown AA, Athanasiu L, Jönsson EG, Hansen T, Gústafsson O, Hall H, Giegling I, Muglia P, Cichon S, Rietschel M, Pietiläinen OP, Peltonen L, Bramon E, Collier D, St Clair D, Sigurdsson E, Petursson H, Rujescu D, Melle I, Werge T, Steen VM, Dale AM et al. (2010)
Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area
69 (1), 90-6
DOI 10.1016/j.biopsych.2010.07.035, PubMed 20950796
Kähler AK, Otnaess MK, Wirgenes KV, Hansen T, Jönsson EG, Agartz I, Hall H, Werge T, Morken G, Mors O, Mellerup E, Dam H, Koefod P, Melle I, Steen VM, Andreassen OA, Djurovic S (2010)
Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples
153B (1), 86-96
DOI 10.1002/ajmg.b.30958, PubMed 19350560
Saetre P, Lundmark P, Wang A, Hansen T, Rasmussen HB, Djurovic S, Melle I, Andreassen OA, Werge T, Agartz I, Hall H, Terenius L, Jönsson EG (2010)
The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis
153B (2), 387-396
DOI 10.1002/ajmg.b.30991, PubMed 19526457
Steen NE, Tesli M, Kähler AK, Methlie P, Hope S, Barrett EA, Larsson S, Mork E, Løvås K, Røssberg JI, Agartz I, Melle I, Djurovic S, Lorentzen S, Berg JP, Andreassen OA (2010)
SRD5A2 is associated with increased cortisol metabolism in schizophrenia spectrum disorders
34 (8), 1500-6
DOI 10.1016/j.pnpbp.2010.08.013, PubMed 20800085
Steinberg S, Mors O, Børglum AD, Gustafsson O, Werge T, Mortensen PB, Andreassen OA, Sigurdsson E, Thorgeirsson TE, Böttcher Y, Olason P, Ophoff RA, Cichon S, Gudjonsdottir IH, Pietiläinen OP, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Athanasiu L, Suvisaari J, Lonnqvist J, Paunio T, Hartmann A, Jürgens G et al. (2010)
Expanding the range of ZNF804A variants conferring risk of psychosis
16 (1), 59-66
DOI 10.1038/mp.2009.149, PubMed 20048749
Tesli M, Athanasiu L, Mattingsdal M, Kähler AK, Gustafsson O, Andreassen BK, Werge T, Hansen T, Mors O, Mellerup E, Koefoed P, Jönsson EG, Agartz I, Melle I, Morken G, Djurovic S, Andreassen OA (2010)
Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample
153B (7), 1276-82
DOI 10.1002/ajmg.b.31098, PubMed 20872766
Vares M, Saetre P, Deng H, Cai G, Liu X, Hansen T, Rasmussen HB, Werge T, Melle I, Djurovic S, Andreassen OA, Agartz I, Hall H, Terenius L, Jönsson EG (2010)
Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia
153B (2), 610-618
DOI 10.1002/ajmg.b.31030, PubMed 19746410
Wirgenes KV, Djurovic S, Sundet K, Agartz I, Mattingsdal M, Athanasiu L, Melle I, Andreassen OA (2010)
Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls
122 (1-3), 31-7
DOI 10.1016/j.schres.2010.05.007, PubMed 20605701
Andreou D, Saetre P, Lundmark P, Hansen T, Timm S, Melle I, Djurovic S, Andreassen OA, Werge T, Hall H, Agartz I, Terenius L, Jönsson EG (2009)
Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia
19 (5), 273-4
DOI 10.1097/YPG.0b013e32832a4fcd, PubMed 19491717
Djurovic S, Le Hellard S, Kähler AK, Jönsson EG, Agartz I, Steen VM, Hall H, Wang AG, Rasmussen HB, Melle I, Werge T, Andreassen OA (2009)
Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)
168 (3), 256-8
DOI 10.1016/j.psychres.2008.08.007, PubMed 19223264
Ingason A, Rujescu D, Cichon S, Sigurdsson E, Sigmundsson T, Pietiläinen OP, Buizer-Voskamp JE, Strengman E, Francks C, Muglia P, Gylfason A, Gustafsson O, Olason PI, Steinberg S, Hansen T, Jakobsen KD, Rasmussen HB, Giegling I, Möller HJ, Hartmann A, Crombie C, Fraser G, Walker N, Lonnqvist J, Suvisaari J et al. (2009)
Copy number variations of chromosome 16p13.1 region associated with schizophrenia
16 (1), 17-25
DOI 10.1038/mp.2009.101, PubMed 19786961
Joyner AH, J CR, Bloss CS, Bakken TE, Rimol LM, Melle I, Agartz I, Djurovic S, Topol EJ, Schork NJ, Andreassen OA, Dale AM (2009)
A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations
106 (36), 15483-8
DOI 10.1073/pnas.0901866106, PubMed 19717458
Jönsson EG, Saetre P, Vares M, Andreou D, Larsson K, Timm S, Rasmussen HB, Djurovic S, Melle I, Andreassen OA, Agartz I, Werge T, Hall H, Terenius L (2009)
DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study
59 (3), 142-50
DOI 10.1159/000218076, PubMed 19439994
Otnaess MK, Djurovic S, Rimol LM, Kulle B, Kähler AK, Jönsson EG, Agartz I, Sundet K, Hall H, Timm S, Hansen T, Callicott JH, Melle I, Werge T, Andreassen OA (2009)
Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia
34 (3), 518-24
DOI 10.1016/j.nbd.2009.03.011, PubMed 19344762
Rimol LM, Agartz I, Djurovic S, Brown AA, Roddey JC, Kähler AK, Mattingsdal M, Athanasiu L, Joyner AH, Schork NJ, Halgren E, Sundet K, Melle I, Dale AM, Andreassen OA, Alzheimer's Disease Neuroimaging Initiative (2009)
Sex-dependent association of common variants of microcephaly genes with brain structure
107 (1), 384-8
DOI 10.1073/pnas.0908454107, PubMed 20080800
Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietiläinen OP, Mors O, Mortensen PB, Sigurdsson E, Gustafsson O, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Suvisaari J, Lonnqvist J, Paunio T, Børglum AD, Hartmann A, Fink-Jensen A, Nordentoft M, Hougaard D, Norgaard-Pedersen B et al. (2009)
Common variants conferring risk of schizophrenia
460 (7256), 744-7
DOI 10.1038/nature08186, PubMed 19571808
Tesli M, Kähler AK, Andreassen BK, Werge T, Mors O, Mellerup E, Koefoed P, Melle I, Morken G, Wirgenes KV, Andreassen OA, Djurovic S (2009)
No association between DGKH and bipolar disorder in a Scandinavian case-control sample
19 (5), 269-72
DOI 10.1097/YPG.0b013e32832d302f, PubMed 19478689
van Schijndel JE, van Loo KM, van Zweeden M, Djurovic S, Andreassen OA, Hansen T, Werge T, Kallunki P, Pedersen JT, Martens GJ (2009)
Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia
43 (15), 1195-9
DOI 10.1016/j.jpsychires.2009.04.006, PubMed 19435634
Wirgenes KV, Djurovic S, Agartz I, Jonsson EG, Werge T, Melle I, Andreassen OA (2009)
Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia
60 (1), 31-6
DOI 10.1159/000235799, PubMed 19729970
Djurovic S, Kähler AK, Kulle B, Jönsson EG, Agartz I, Le Hellard S, Hall H, Jakobsen KD, Hansen T, Melle I, Werge T, Steen VM, Andreassen OA (2008)
A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE)
107 (2-3), 242-8
DOI 10.1016/j.schres.2008.10.010, PubMed 19022628
Jönsson EG, Larsson K, Vares M, Hansen T, Wang AG, Djurovic S, Rønningen KS, Andreassen OA, Agartz I, Werge T, Terenius L, Hall H (2008)
Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study
147B (6), 976-82
DOI 10.1002/ajmg.b.30671, PubMed 18165967
Kähler AK, Djurovic S, Kulle B, Jönsson EG, Agartz I, Hall H, Opjordsmoen S, Jakobsen KD, Hansen T, Melle I, Werge T, Steen VM, Andreassen OA (2008)
Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
147B (7), 1089-100
DOI 10.1002/ajmg.b.30726, PubMed 18384059
Le Hellard S, Mühleisen TW, Djurovic S, Fernø J, Ouriaghi Z, Mattheisen M, Vasilescu C, Raeder MB, Hansen T, Strohmaier J, Georgi A, Brockschmidt FF, Melle I, Nenadic I, Sauer H, Rietschel M, Nöthen MM, Werge T, Andreassen OA, Cichon S, Steen VM (2008)
Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples
15 (5), 463-72
DOI 10.1038/mp.2008.110, PubMed 18936756
Olsen L, Hansen T, Jakobsen KD, Djurovic S, Melle I, Agartz I, Hall H, Ullum H, Timm S, Wang AG, Jönsson EG, Andreassen OA, Werge T (2008)
The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
9, 39
DOI 10.1186/1471-2350-9-39, PubMed 18460190
Rujescu D, Ingason A, Cichon S, Pietiläinen OP, Barnes MR, Toulopoulou T, Picchioni M, Vassos E, Ettinger U, Bramon E, Murray R, Ruggeri M, Tosato S, Bonetto C, Steinberg S, Sigurdsson E, Sigmundsson T, Petursson H, Gylfason A, Olason PI, Hardarsson G, Jonsdottir GA, Gustafsson O, Fossdal R, Giegling I et al. (2008)
Disruption of the neurexin 1 gene is associated with schizophrenia
18 (5), 988-96
DOI 10.1093/hmg/ddn351, PubMed 18945720
Saetre P, Agartz I, De Franciscis A, Lundmark P, Djurovic S, Kähler A, Andreassen OA, Jakobsen KD, Rasmussen HB, Werge T, Hall H, Terenius L, Jönsson EG (2008)
Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample
106 (2-3), 237-41
DOI 10.1016/j.schres.2008.08.024, PubMed 18818052
Stefansson H, Rujescu D, Cichon S, Pietiläinen OP, Ingason A, Steinberg S, Fossdal R, Sigurdsson E, Sigmundsson T, Buizer-Voskamp JE, Hansen T, Jakobsen KD, Muglia P, Francks C, Matthews PM, Gylfason A, Halldorsson BV, Gudbjartsson D, Thorgeirsson TE, Sigurdsson A, Jonasdottir A, Jonasdottir A, Bjornsson A, Mattiasdottir S, Blondal T et al. (2008)
Large recurrent microdeletions associated with schizophrenia
455 (7210), 232-6
DOI 10.1038/nature07229, PubMed 18668039
Zacchigna S, Ostli EK, Arsic N, Pattarini L, Giacca M, Djurovic S (2008)
A novel myogenic cell line with phenotypic properties of muscle progenitors
J. Mol. Med., 86 (1), 105-115
DOI 10.1007/s00109-007-0268-0
Djurovic S, Berge KE, Birkenes B, Braaten Ø, Retterstøl L (2007)
The effect of red wine on plasma leptin levels and vasoactive factors from adipose tissue: a randomized crossover trial
42 (6), 525-8
DOI 10.1093/alcalc/agm056, PubMed 17670801
Hansen T, Olsen L, Lindow M, Jakobsen KD, Ullum H, Jonsson E, Andreassen OA, Djurovic S, Melle I, Agartz I, Hall H, Timm S, Wang AG, Werge T (2007)
Brain expressed microRNAs implicated in schizophrenia etiology
2 (9), e873
DOI 10.1371/journal.pone.0000873, PubMed 17849003
Pasalic D, Bilic-Zulle L, Stimac D, Krznaric Z, Ferencak G, Grskovic B, Djurovic S, Stavljenic-Rukavina A (2006)
Influence of different lipoprotein lipase gene polymorphisms on developing pancreatitis of different etiology in Croatian patients
Period. Biol., 108 (5), 581-586
Eliassen KA, Brodal BP, Svindland A, Osmundsen H, Rønning H, Djurovic S, Berg K (2005)
Activity of peroxisomal enzymes, and levels of polyamines in LPA-transgenic mice on two different diets
4, 23
DOI 10.1186/1476-511X-4-23, PubMed 16202171
Stanojevic NB, Ivanovic ZJ, Djurovic S, Kalimanovska VS, Spasic S, Ostric DK, Memon L (2005)
Lack of association between low HDL-cholesterol and elevated circulating cellular adhesion molecules in normolipidemic CAD patients and healthy subjects
Int. Heart J., 46 (4), 593-600
DOI 10.1536/ihj.46.593
Woldbaek PR, Sande JB, Strømme TA, Lunde PK, Djurovic S, Lyberg T, Christensen G, Tønnessen T (2005)
Daily administration of interleukin-18 causes myocardial dysfunction in healthy mice
289 (2), H708-14
DOI 10.1152/ajpheart.01179.2004, PubMed 15821032
Djurovic S, Iversen N, Jeansson S, Hoover F, Christensen G (2004)
Comparison of nonviral transfection and adeno-associated viral transduction on cardiomyocytes
28 (1), 21-32
DOI 10.1385/MB:28:1:21, PubMed 15456960
Djurovic S, Kristansen H, Sletten M, Halvorsen K, Berg K (2004)
Variations in transfection efficiency of VEGF(165) and VEGF(121)-cDNA - Its effects on proliferation and migration of human endothelial cells
Mol. Biotechnol., 26 (1), 7-16
DOI 10.1385/MB:26:1:7
Pasalić D, Jurcić Z, Stipancić G, Ferencak G, Leren TP, Djurovic S, Stavljenić-Rukavina A (2004)
Missense mutation W86R in exon 3 of the lipoprotein lipase gene in a boy with chylomicronemia
343 (1-2), 179-84
DOI 10.1016/j.cccn.2004.01.029, PubMed 15115692
Bogavac-Stanojevic N, Djurovic S, Jelic-Ivanovic Z, Spasojevic-Kalimanovska V, Kalimanovska-Ostric D (2003)
Circulating transforming growth factor-beta(1), lipoprotein(a) and cellular adhesion molecules in angiographically assessed coronary artery disease
Clin. Chem. Lab. Med., 41 (7), 893-898
DOI 10.1515/CCLM.2003.135
Os I, Høieggen A, Larsen A, Sandset PM, Djurovic S, Berg K, Os A, Birkeland K, Westheim A (2003)
Smoking and relation to other risk factors in postmenopausal women with coronary artery disease, with particular reference to whole blood viscosity and beta-cell function
253 (2), 232-9
DOI 10.1046/j.1365-2796.2003.01110.x, PubMed 12542565
Os I, Høieggen A, Larsen A, Sandset PM, Djurovic S, Berg K, Os A, Birkeland KI, Westheim A (2003)
Smoking and relation to other risk factors in postmenopausal women with coronary artery disease, with particular reference to whole blood viscosity and beta-cell function
In Journal of internal medicine, Blackwell Scientific Publ., Oxford, 253(2003)2, s.232-9
BIBSYS 041722221
Berg K, Svindland A, Smith AJ, Lawn RM, Djurovic S, Aleström A, Aleström P, Eliassen K (2002)
Spontaneous atherosclerosis in the proximal aorta of LPA transgenic mice on a normal diet
163 (1), 99-104
DOI 10.1016/s0021-9150(01)00772-9, PubMed 12048126
Clausen T, Djurovic S, Reseland JE, Berg K, Drevon CA, Henriksen T (2002)
Altered plasma concentrations of leptin, transforming growth factor-beta(1) and plasminogen activator inhibitor type 2 at 18 weeks of gestation in women destined to develop pre-eclampsia. Circulating markers of disturbed placentation?
23 (5), 380-5
DOI 10.1053/plac.2002.0828, PubMed 12061853
Djurovic S, Clausen T, Wergeland R, Brosstad F, Berg K, Henriksen T (2002)
Absence of enhanced systemic inflammatory response at 18 weeks of gestation in women with subsequent pre-eclampsia
109 (7), 759-64
DOI 10.1111/j.1471-0528.2002.01330.x, PubMed 12135211
Os I, Djurovic S, Seljeflot I, Berg K (2002)
Transforming growth factor (TGF)-beta(1) inversely related to vascular cell adhesion molecule-1 in postmenopausal women with coronary artery disease. A possible mechanism for the putative cardioprotective role of TGF-beta(1)?
J. Intern. Med., 251 (3), 223-227
DOI 10.1046/j.1365-2796.2002.00950.x
Os I, Os A, Sandset PM, Bølling S, Seljeflot I, Djurovic S, Westheim A (2002)
Hormone replacement therapy does not affect plasma homocysteine in postmenopausal women with coronary artery disease. Free tissue factor pathway inhibitor antigen, a circulating anticoagulant, is related to plasma homocysteine
98 (1-2), 6-12
DOI 10.1159/000064667, PubMed 12373040
Clausen T, Djurovic S, Henriksen T (2001)
Dyslipidemia in early second trimester is mainly a feature of women with early onset pre-eclampsia
108 (10), 1081-7
DOI 10.1111/j.1471-0528.2001.00247.x, PubMed 11702841
Retterstol L, Djurovic S, Bohn M, Bakken A, Erikssen J, Berg K (2001)
Plasma N-terminal pro-atrial natriuretic peptide predicts death after premature myocardial infarction, but not as well as radionuclide ejection fraction. A ten-year follow-up study
35 (6), 373-8
DOI 10.1080/14017430152754853, PubMed 11837516
Berg K, Djurovic S, Rainwater DL (2000)
Gene encoding the apo(a) protein in LPA
Atherosclerosis, 148 (1), 203
Clausen T, Djurovic S, Brosstad FR, Berg K, Henriksen T (2000)
Altered circulating levels of adhesion molecules at 18 weeks' gestation among women with eventual preeclampsia: indicators of disturbed placentation in absence of evidence of endothelial dysfunction?
182 (2), 321-5
DOI 10.1016/s0002-9378(00)70218-3, PubMed 10694331
Djurovic S, Os I, Hofstad AE, Abdelnoor M, Westheim A, Berg K (2000)
Increased plasma concentrations of TGF-beta1 after hormone replacement therapy
247 (2), 279-85
DOI 10.1046/j.1365-2796.2000.00648.x, PubMed 10692092
Svindland A, Berg K, Eliassen K, Lawn RM, Djurovic S, Aleström P, Noren T, Smith A (2000)
Histopathology of arterial lesions in LPA transgenic mice on cholesterol-enriched chow
153 (2), 349-54
DOI 10.1016/s0021-9150(00)00430-5, PubMed 11164423
Christensen B, Landaas S, Stensvold I, Djurovic S, Retterstol L, Ringstad J, Berg K, Thelle DS (1999)
Whole blood folate, homocysteine in serum, and risk of first acute myocardial infarction
Atherosclerosis, 147 (2), 317-326
DOI 10.1016/S0021-9150(99)00202-6
Djurovic S, Thelle DS, Ringstad J, Christensen B, Berg K (1999)
Altered serum concentrations of TGF-beta(1) and Lp(a) lipoprotein and their correlation in patients with first acute myocardial infarction
Nutr. Metab. Carbiovasc. Dis., 9 (5), 250-254
Berge KE, Djurovic S, Muller HJ, Alestrom P, Berg K (1997)
Studies on effects of Lp(a) lipoprotein on gene expression in endothelial cells in vitro
Clin. Genet., 52 (5), 314-325
Berge KE, Djurovic S, Muller HJ, Alestrøm P, Berg K (1997)
Studies on effects of Lp(a) lipoprotein on gene expression in endothelial cells in vitro
52 (5), 314-25
DOI 10.1111/j.1399-0004.1997.tb04349.x, PubMed 9520122
Djurovic S, Berg K (1997)
Epidemiology of Lp(a) lipoprotein: its role in atherosclerotic/thrombotic disease
Clin. Genet., 52 (5), 281-292
Djurovic S, Schjetlein R, Wisloff F, Haugen G, Berg K (1997)
Increased levels of intercellular adhesion molecules and vascular cell adhesion molecules in pre-eclampsia
Br. J. Obstet. Gynaecol., 104 (4), 466-470
DOI 10.1111/j.1471-0528.1997.tb11499.x
Djurovic S, Schjetlein R, Wisloff F, Haugen G, Husby H, Berg K (1997)
Plasma concentrations of Lp(a) lipoprotein and TGF-beta(1) are altered in preeclampsia
Clin. Genet., 52 (5), 371-376
