Publications 2019

Watson HJ, Yilmaz Z, Thornton LM, Hübel C, Coleman JRI, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Medland SE, Ripke S, Yao S, Giusti-Rodríguez P, Anorexia Nervosa Genetics Initiative, Hanscombe KB, Purves KL, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Baker JH, Berrettini WH, Boehm I et al. (2019)
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Nat Genet, 51 (8), 1207-1214
DOI 10.1038/s41588-019-0439-2, PubMed 31308545

Publications 2018

Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A et al. (2018)
Analysis of shared heritability in common disorders of the brain
Science, 360 (6395)
DOI 10.1126/science.aap8757, PubMed 29930110

Mattingsdal M, Jentoft S, Tørresen OK, Knutsen H, Hansen MM, Robalo JI, Zagrodzka Z, André C, Gonzalez EB (2018)
A continuous genome assembly of the corkwing wrasse (Symphodus melops)
Genomics, 110 (6), 399-403
DOI 10.1016/j.ygeno.2018.04.009, PubMed 29665418

Publications 2016

Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, Antaki D, Shetty A, Holmans PA, Pinto D, Gujral M, Brandler WM, Malhotra D, Wang Z, Fajarado KVF, Maile MS, Ripke S, Agartz I, Albus M, Alexander M, Amin F, Atkins J, Bacanu SA, Belliveau RA, Bergen SE et al. (2016)
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Nat Genet, 49 (1), 27-35
DOI 10.1038/ng.3725, PubMed 27869829

Publications 2015

Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM (2015)
Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms
PLoS One, 10 (5), e0128048
DOI 10.1371/journal.pone.0128048, PubMed 25978331

Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM (2015)
Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
PLoS One, 10 (4), e0123057
DOI 10.1371/journal.pone.0123057, PubMed 25853426

Andreassen OA, Thompson WK, Schork AJ, Ripke S, Mattingsdal M, Kelsoe JR, Kendler KS, O'Donovan MC, Rujescu D, Werge T, Sklar P, Psychiatric Genomics Consortium (PGC), Bipolar Disorder and Schizophrenia Working Groups, Roddey JC, Chen CH, McEvoy L, Desikan RS, Djurovic S, Dale AM (2015)
Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate
PLoS Genet, 11 (11), e1005544
DOI 10.1371/journal.pgen.1005544, PubMed 26540268

Goulart LF, Bettella F, Sønderby IE, Schork AJ, Thompson WK, Mattingsdal M, Steen VM, Zuber V, Wang Y, Dale AM, PRACTICAL/ELLIPSE consortium, Andreassen OA, Djurovic S (2015)
MicroRNAs enrichment in GWAS of complex human phenotypes
BMC Genomics, 16, 304
DOI 10.1186/s12864-015-1513-5, PubMed 25884492

Lee SH, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AA, Ripke S, Andreassen OA, Frisell T, Gusev A, Hu X, Karlsson R, Mantzioris VX, McGrath JJ, Mehta D, Stahl EA, Zhao Q, Kendler KS, Sullivan PF, Price AL, O'Donovan M, Okada Y, Mowry BJ, Raychaudhuri S, Wray NR, Schizophrenia Working Group of the Psychiatric Genomics Consortium and Rheumatoid Arthritis Consortium International et al. (2015)
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis
Int J Epidemiol, 44 (5), 1706-21
DOI 10.1093/ije/dyv136, PubMed 26286434

Srinivasan S, Bettella F, Mattingsdal M, Wang Y, Witoelar A, Schork AJ, Thompson WK, Zuber V, Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, Winsvold BS, Zwart JA, Collier DA, Desikan RS, Melle I, Werge T, Dale AM, Djurovic S, Andreassen OA (2015)
Genetic Markers of Human Evolution Are Enriched in Schizophrenia
Biol Psychiatry, 80 (4), 284-292
DOI 10.1016/j.biopsych.2015.10.009, PubMed 26681495

Tesli M, Kauppi K, Bettella F, Brandt CL, Kaufmann T, Espeseth T, Mattingsdal M, Agartz I, Melle I, Djurovic S, Westlye LT, Andreassen OA (2015)
Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder
PLoS One, 10 (7), e0134202
DOI 10.1371/journal.pone.0134202, PubMed 26222050

Publications 2014

Andreassen OA, Harbo HF, Wang Y, Thompson WK, Schork AJ, Mattingsdal M, Zuber V, Bettella F, Ripke S, Kelsoe JR, Kendler KS, O'Donovan MC, Sklar P, Psychiatric Genomics Consortium (PGC) Bipolar Disorder and Schizophrenia Work Groups, International Multiple Sclerosis Genetics Consortium (IMSGC), McEvoy LK, Desikan RS, Lie BA, Djurovic S, Dale AM (2014)
Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci
Mol Psychiatry, 20 (2), 207-14
DOI 10.1038/mp.2013.195, PubMed 24468824

Boraska V, Franklin CS, Floyd JA, Thornton LM, Huckins LM, Southam L, Rayner NW, Tachmazidou I, Klump KL, Treasure J, Lewis CM, Schmidt U, Tozzi F, Kiezebrink K, Hebebrand J, Gorwood P, Adan RA, Kas MJ, Favaro A, Santonastaso P, Fernández-Aranda F, Gratacos M, Rybakowski F, Dmitrzak-Weglarz M, Kaprio J et al. (2014)
A genome-wide association study of anorexia nervosa
Mol Psychiatry, 19 (10), 1085-94
DOI 10.1038/mp.2013.187, PubMed 24514567

Kauppi K, Westlye LT, Tesli M, Bettella F, Brandt CL, Mattingsdal M, Ueland T, Espeseth T, Agartz I, Melle I, Djurovic S, Andreassen OA (2014)
Polygenic risk for schizophrenia associated with working memory-related prefrontal brain activation in patients with schizophrenia and healthy controls
Schizophr Bull, 41 (3), 736-43
DOI 10.1093/schbul/sbu152, PubMed 25392519

Tesli M, Espeseth T, Bettella F, Mattingsdal M, Aas M, Melle I, Djurovic S, Andreassen OA (2014)
Polygenic risk score and the psychosis continuum model
Acta Psychiatr Scand, 130 (4), 311-7
DOI 10.1111/acps.12307, PubMed 24961959

Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, Almasy L, Almeida J, Alpert K, Andreasen NC, Andreassen OA, Apostolova LG, Appel K, Armstrong NJ, Aribisala B, Bastin ME et al. (2014)
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Brain Imaging Behav, 8 (2), 153-82
DOI 10.1007/s11682-013-9269-5, PubMed 24399358

Publications 2013

Andreassen OA, Thompson WK, Schork AJ, Ripke S, Mattingsdal M, Kelsoe JR, Kendler KS, O'Donovan MC, Rujescu D, Werge T, Sklar P, Psychiatric Genomics Consortium (PGC), Bipolar Disorder and Schizophrenia Working Groups, Roddey JC, Chen CH, McEvoy L, Desikan RS, Djurovic S, Dale AM (2013)
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate
PLoS Genet, 9 (4), e1003455
DOI 10.1371/journal.pgen.1003455, PubMed 23637625

Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, Andreassen OA, Anjorin A, Anney R, Anttila V, Arking DE, Asherson P, Azevedo MH, Backlund L, Badner JA, Bailey AJ et al. (2013)
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Nat Genet, 45 (9), 984-94
DOI 10.1038/ng.2711, PubMed 23933821

Publications 2012

Athanasiu L, Brown AA, Birkenaes AB, Mattingsdal M, Agartz I, Melle I, Steen VM, Andreassen OA, Djurovic S (2012)
Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study
Psychiatry Res, 197 (3), 327-36
DOI 10.1016/j.psychres.2011.12.036, PubMed 22417934

Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM, Alzheimer's Disease Neuroimaging Initiative et al. (2012)
Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans
Proc Natl Acad Sci U S A, 109 (10), 3985-90
DOI 10.1073/pnas.1105829109, PubMed 22343285

Brown AA, Jensen J, Nikolova YS, Djurovic S, Agartz I, Server A, Ferrell RE, Manuck SB, Mattingsdal M, Melle I, Hariri AR, Frigessi A, Andreassen OA (2012)
Genetic variants affecting the neural processing of human facial expressions: evidence using a genome-wide functional imaging approach
Transl Psychiatry, 2, e143
DOI 10.1038/tp.2012.67, PubMed 22828495

Christoforou A, Dondrup M, Mattingsdal M, Mattheisen M, Giddaluru S, Nöthen MM, Rietschel M, Cichon S, Djurovic S, Andreassen OA, Jonassen I, Steen VM, Puntervoll P, Le Hellard S (2012)
Linkage-disequilibrium-based binning affects the interpretation of GWASs
Am J Hum Genet, 90 (4), 727-33
DOI 10.1016/j.ajhg.2012.02.025, PubMed 22444669

Dieset I, Djurovic S, Tesli M, Hope S, Mattingsdal M, Michelsen A, Joa I, Larsen TK, Agartz I, Melle I, Røssberg JI, Aukrust P, Andreassen OA, Ueland T (2012)
Up-regulation of NOTCH4 gene expression in bipolar disorder
Am J Psychiatry, 169 (12), 1292-300
DOI 10.1176/appi.ajp.2012.11091431, PubMed 23212060

Ersland KM, Christoforou A, Stansberg C, Espeseth T, Mattheisen M, Mattingsdal M, Hardarson GA, Hansen T, Fernandes CP, Giddaluru S, Breuer R, Strohmaier J, Djurovic S, Nöthen MM, Rietschel M, Lundervold AJ, Werge T, Cichon S, Andreassen OA, Reinvang I, Steen VM, Le Hellard S (2012)
Gene-based analysis of regionally enriched cortical genes in GWAS data sets of cognitive traits and psychiatric disorders
PLoS One, 7 (2), e31687
DOI 10.1371/journal.pone.0031687, PubMed 22384057

Gervin K, Vigeland MD, Mattingsdal M, Hammerø M, Nygård H, Olsen AO, Brandt I, Harris JR, Undlien DE, Lyle R (2012)
DNA methylation and gene expression changes in monozygotic twins discordant for psoriasis: identification of epigenetically dysregulated genes
PLoS Genet, 8 (1), e1002454
DOI 10.1371/journal.pgen.1002454, PubMed 22291603

Mattingsdal M, Brown AA, Djurovic S, Sønderby IE, Server A, Melle I, Agartz I, Hovig E, Jensen J, Andreassen OA (2012)
Pathway analysis of genetic markers associated with a functional MRI faces paradigm implicates polymorphisms in calcium responsive pathways
Neuroimage, 70, 143-9
DOI 10.1016/j.neuroimage.2012.12.035, PubMed 23274185

Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS et al. (2012)
Identification of common variants associated with human hippocampal and intracranial volumes
Nat Genet, 44 (5), 552-61
DOI 10.1038/ng.2250, PubMed 22504417

Wirgenes KV, Sønderby IE, Haukvik UK, Mattingsdal M, Tesli M, Athanasiu L, Sundet K, Røssberg JI, Dale AM, Brown AA, Agartz I, Melle I, Djurovic S, Andreassen OA (2012)
TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders
Transl Psychiatry, 2, e112
DOI 10.1038/tp.2012.39, PubMed 22832956

Publications 2011

Humphreys K, Grankvist A, Leu M, Hall P, Liu J, Ripatti S, Rehnström K, Groop L, Klareskog L, Ding B, Grönberg H, Xu J, Pedersen NL, Lichtenstein P, Mattingsdal M, Andreassen OA, O'Dushlaine C, Purcell SM, Sklar P, Sullivan PF, Hultman CM, Palmgren J, Magnusson PK (2011)
The genetic structure of the Swedish population
PLoS One, 6 (8), e22547
DOI 10.1371/journal.pone.0022547, PubMed 21829632

Tesli M, Koefoed P, Athanasiu L, Mattingsdal M, Gustafsson O, Agartz I, Rimol LM, Brown A, Wirgenes KV, Smorr LL, Kähler AK, Werge T, Mors O, Mellerup E, Jönsson EG, Melle I, Morken G, Djurovic S, Andreassen OA (2011)
Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples
Am J Med Genet B Neuropsychiatr Genet, 156B (8), 969-74
DOI 10.1002/ajmg.b.31244, PubMed 21972176

Publications 2010

Athanasiu L, Mattingsdal M, Kähler AK, Brown A, Gustafsson O, Agartz I, Giegling I, Muglia P, Cichon S, Rietschel M, Pietiläinen OP, Peltonen L, Bramon E, Collier D, Clair DS, Sigurdsson E, Petursson H, Rujescu D, Melle I, Steen VM, Djurovic S, Andreassen OA (2010)
Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
J Psychiatr Res, 44 (12), 748-53
DOI 10.1016/j.jpsychires.2010.02.002, PubMed 20185149

Athanasiu L, Mattingsdal M, Melle I, Inderhaug E, Lien T, Agartz I, Lorentzen S, Morken G, Andreassen OA, Djurovic S (2010)
Intron 12 in NTRK3 is associated with bipolar disorder
Psychiatry Res, 185 (3), 358-62
DOI 10.1016/j.psychres.2010.05.011, PubMed 20554328

Djurovic S, Gustafsson O, Mattingsdal M, Athanasiu L, Bjella T, Tesli M, Agartz I, Lorentzen S, Melle I, Morken G, Andreassen OA (2010)
A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample
J Affect Disord, 126 (1-2), 312-6
DOI 10.1016/j.jad.2010.04.007, PubMed 20451256

Tesli M, Athanasiu L, Mattingsdal M, Kähler AK, Gustafsson O, Andreassen BK, Werge T, Hansen T, Mors O, Mellerup E, Koefoed P, Jönsson EG, Agartz I, Melle I, Morken G, Djurovic S, Andreassen OA (2010)
Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample
Am J Med Genet B Neuropsychiatr Genet, 153B (7), 1276-82
DOI 10.1002/ajmg.b.31098, PubMed 20872766

Wirgenes KV, Djurovic S, Sundet K, Agartz I, Mattingsdal M, Athanasiu L, Melle I, Andreassen OA (2010)
Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls
Schizophr Res, 122 (1-3), 31-7
DOI 10.1016/j.schres.2010.05.007, PubMed 20605701

Publications 2009

Holla ØL, Nakken S, Mattingsdal M, Ranheim T, Berge KE, Defesche JC, Leren TP (2009)
Effects of intronic mutations in the LDLR gene on pre-mRNA splicing: Comparison of wet-lab and bioinformatics analyses
Mol Genet Metab, 96 (4), 245-52
DOI 10.1016/j.ymgme.2008.12.014, PubMed 19208450

Rimol LM, Agartz I, Djurovic S, Brown AA, Roddey JC, Kähler AK, Mattingsdal M, Athanasiu L, Joyner AH, Schork NJ, Halgren E, Sundet K, Melle I, Dale AM, Andreassen OA, Alzheimer's Disease Neuroimaging Initiative (2009)
Sex-dependent association of common variants of microcephaly genes with brain structure
Proc Natl Acad Sci U S A, 107 (1), 384-8
DOI 10.1073/pnas.0908454107, PubMed 20080800

Wangensteen T, Kolsgaard ML, Mattingsdal M, Joner G, Tonstad S, Undlien D, Retterstol L (2009)
Mutations in the melanocortin 4 receptor (MC4R) gene in obese patients in Norway
Exp Clin Endocrinol Diabetes, 117 (6), 266-73
DOI 10.1055/s-0028-1102942, PubMed 19301229

Publications 2008

Gilfillan GD, Selmer KK, Roxrud I, Smith R, Kyllerman M, Eiklid K, Kroken M, Mattingsdal M, Egeland T, Stenmark H, Sjøholm H, Server A, Samuelsson L, Christianson A, Tarpey P, Whibley A, Stratton MR, Futreal PA, Teague J, Edkins S, Gecz J, Turner G, Raymond FL, Schwartz C, Stevenson RE et al. (2008)
SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome
Am J Hum Genet, 82 (4), 1003-10
DOI 10.1016/j.ajhg.2008.01.013, PubMed 18342287

Ranheim T, Mattingsdal M, Lindvall JM, Holla OL, Berge KE, Kulseth MA, Leren TP (2008)
Genome-wide expression analysis of cells expressing gain of function mutant D374Y-PCSK9
J Cell Physiol, 217 (2), 459-67
DOI 10.1002/jcp.21519, PubMed 18570182

Rødland EK, Mattingsdal M, Olstad OK, Ovstebø R, Kierulf P, Muller F, Frøland SS (2008)
Expression of genes in normal human monocytes in response to Aspergillus fumigatus
Med Mycol, 46 (4), 327-36
DOI 10.1080/13693780701874507, PubMed 18415839

Publications 2007

Erichsen AK, Inderhaug E, Mattingsdal M, Eiklid K, Tallaksen CM (2007)
Seven novel mutations and four exon deletions in a collection of Norwegian patients with SPG4 hereditary spastic paraplegia
Eur J Neurol, 14 (7), 809-14
DOI 10.1111/j.1468-1331.2007.01861.x, PubMed 17594340

Publications 2006

Clausen OP, Aass HC, Beigi M, Purdie KJ, Proby CM, Brown VL, Mattingsdal M, Micci F, Kølvraa S, Bolund L, Deangelis PM (2006)
Are keratoacanthomas variants of squamous cell carcinomas? A comparison of chromosomal aberrations by comparative genomic hybridization
J Invest Dermatol, 126 (10), 2308-15
DOI 10.1038/sj.jid.5700375, PubMed 16728973

Publications 2003

Puntervoll P, Linding R, Gemünd C, Chabanis-Davidson S, Mattingsdal M, Cameron S, Martin DM, Ausiello G, Brannetti B, Costantini A, Ferrè F, Maselli V, Via A, Cesareni G, Diella F, Superti-Furga G, Wyrwicz L, Ramu C, McGuigan C, Gudavalli R, Letunic I, Bork P, Rychlewski L, Küster B, Helmer-Citterich M et al. (2003)
ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins
Nucleic Acids Res, 31 (13), 3625-30
DOI 10.1093/nar/gkg545, PubMed 12824381