Jens Pahnke
- Department of Neuro-/Pathology
- 23071466 / 47804637
Oslo University Hospital
Publications 2024
Apolar Extracts of St. John's Wort Alleviate the Effects of β-Amyloid Toxicity in Early Alzheimer's Disease
Int J Mol Sci, 25 (2)
DOI 10.3390/ijms25021301, PubMed 38279301
Evaluation of cerebrospinal fluid (CSF) and interstitial fluid (ISF) mouse proteomes for the validation and description of Alzheimer's disease biomarkers
J Neurosci Methods, 411, 110239
DOI 10.1016/j.jneumeth.2024.110239, PubMed 39102902
Performance and Sensitivity of [99mTc]Tc-sestamibi Compared with Positron Emission Tomography Radiotracers to Measure P-glycoprotein Function in the Kidneys and Liver
Mol Pharm, 21 (2), 932-943
DOI 10.1021/acs.molpharmaceut.3c01036, PubMed 38225758
Genome-wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors
Acta Neuropathol, 148 (1), 68
DOI 10.1007/s00401-024-02836-5, PubMed 39580368
ABCC1 Is a ΔNp63 Target Gene Overexpressed in Squamous Cell Carcinoma
Int J Mol Sci, 25 (16)
DOI 10.3390/ijms25168741, PubMed 39201428
The atorvastatin metabolite pattern in muscle tissue and blood plasma is associated with statin muscle side effects in patients with coronary heart disease; An exploratory case-control study
Atheroscler Plus, 55, 31-38
DOI 10.1016/j.athplu.2024.01.001, PubMed 38293288
25-Hydroxycholesterol attenuates tumor necrosis factor alpha-induced blood-brain barrier breakdown in vitro
Biochim Biophys Acta Mol Basis Dis, 1870 (8), 167479
DOI 10.1016/j.bbadis.2024.167479, PubMed 39181516
First-in-human evaluation of 6-bromo-7-[11C]methylpurine, a PET tracer for assessing the function of multidrug resistance-associated proteins in different tissues
Eur J Nucl Med Mol Imaging, 51 (13), 3900-3911
DOI 10.1007/s00259-024-06851-2, PubMed 39060376
Advancing 6-bromo-7-[11C]methylpurine to clinical use: improved regioselective radiosynthesis, non-clinical toxicity data and human dosimetry estimates
EJNMMI Radiopharm Chem, 9 (1), 34
DOI 10.1186/s41181-024-00265-z, PubMed 38683266
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition
Eur J Med Chem, 266, 116130
DOI 10.1016/j.ejmech.2024.116130, PubMed 38218127
Artificial intelligence in surgical pathology - Where do we stand, where do we go?
Eur J Surg Oncol, 109541 (in press)
DOI 10.1016/j.ejso.2024.109541, PubMed 39694737
Emerging Role of ABC Transporters in Glia Cells in Health and Diseases of the Central Nervous System
Cells, 13 (9)
DOI 10.3390/cells13090740, PubMed 38727275
Publications 2023
Time- and Sex-Dependent Effects of Fingolimod Treatment in a Mouse Model of Alzheimer's Disease
Biomolecules, 13 (2)
DOI 10.3390/biom13020331, PubMed 36830699
TNFα Activates the Liver X Receptor Signaling Pathway and Promotes Cholesterol Efflux from Human Brain Pericytes Independently of ABCA1
Int J Mol Sci, 24 (6)
DOI 10.3390/ijms24065992, PubMed 36983062
Physiological expression of mutated TAU impaired astrocyte activity and exacerbates β-amyloid pathology in 5xFAD mice
J Neuroinflammation, 20 (1), 174
DOI 10.1186/s12974-023-02823-9, PubMed 37496076
TGFBR3L is associated with gonadotropin production in non-functioning gonadotroph pituitary neuroendocrine tumours
Pituitary, 26 (2), 227-236
DOI 10.1007/s11102-023-01310-x, PubMed 36952069
[11C]metoclopramide is a sensitive radiotracer to measure moderate decreases in P-glycoprotein function at the blood-brain barrier
J Cereb Blood Flow Metab, 44 (1), 142-152
DOI 10.1177/0271678X231202336, PubMed 37728771
ABC Transporter C1 Prevents Dimethyl Fumarate from Targeting Alzheimer's Disease
Biology (Basel), 12 (7)
DOI 10.3390/biology12070932, PubMed 37508364
HD_BPMDS: a curated binary pattern multitarget dataset of Huntington's disease-targeting agents
J Cheminform, 15 (1), 109
DOI 10.1186/s13321-023-00775-z, PubMed 37978560
Publications 2022
Screening of Alzheimer's Disease With Multiwavelength Stokes Polarimetry in a Mouse Model
IEEE Trans Med Imaging, 41 (4), 977-982
DOI 10.1109/TMI.2021.3129700, PubMed 34807820
Isotope-labeled amyloid-β does not transmit to the brain in a prion-like manner after peripheral administration
EMBO Rep, 23 (7), e54405
DOI 10.15252/embr.202154405, PubMed 35620875
Physicochemistry shapes bioactivity landscape of pan-ABC transporter modulators: Anchor point for innovative Alzheimer's disease therapeutics
Int J Biol Macromol, 217, 775-791
DOI 10.1016/j.ijbiomac.2022.07.062, PubMed 35839956
Structural feature-driven pattern analysis for multitarget modulator landscapes
Bioinformatics, 38 (5), 1385-1392
DOI 10.1093/bioinformatics/btab832, PubMed 34888617
Indole Derivatives as New Structural Class of Potent and Antiproliferative Inhibitors of Monocarboxylate Transporter 1 (MCT1; SLC16A1)
J Med Chem, 66 (1), 657-676
DOI 10.1021/acs.jmedchem.2c01612, PubMed 36584238
A curated binary pattern multitarget dataset of focused ATP-binding cassette transporter inhibitors
Sci Data, 9 (1), 446
DOI 10.1038/s41597-022-01506-z, PubMed 35882865
A Novel Huntington's Disease Assessment Platform to Support Future Drug Discovery and Development
Int J Mol Sci, 23 (23)
DOI 10.3390/ijms232314763, PubMed 36499090
Use of PET Imaging to Assess the Efficacy of Thiethylperazine to Stimulate Cerebral MRP1 Transport Activity in Wild-Type and APP/PS1-21 Mice
Int J Mol Sci, 23 (12)
DOI 10.3390/ijms23126514, PubMed 35742960
Publications 2021
Machine Learning-Supported Analyses Improve Quantitative Histological Assessments of Amyloid-β Deposits and Activated Microglia
J Alzheimers Dis, 79 (2), 597-605
DOI 10.3233/JAD-201120, PubMed 33337377
Corticotroph Aggressive Pituitary Tumors and Carcinomas Frequently Harbor ATRX Mutations
J Clin Endocrinol Metab, 106 (4), 1183-1194
DOI 10.1210/clinem/dgaa749, PubMed 33106857
Role of ABCA7 in Human Health and in Alzheimer's Disease
Int J Mol Sci, 22 (9)
DOI 10.3390/ijms22094603, PubMed 33925691
Intraoperative DNA methylation classification of brain tumors impacts neurosurgical strategy
Neurooncol Adv, 3 (1), vdab149
DOI 10.1093/noajnl/vdab149, PubMed 34729487
[Approval first, research afterwards?]
Tidsskr Nor Laegeforen, 141
DOI 10.4045/tidsskr.21.0590, PubMed 34597005
Approval first, research afterwards?
Tidsskr. Nor. Laegeforen., 141 (13), 1251-1252
The Norwegian childhood cancer biobank
Cancer Rep (Hoboken), 5 (8), e1555
DOI 10.1002/cnr2.1555, PubMed 34541832
Development of deep learning models for microglia analyses in brain tissue using DeePathology™ STUDIO
J Neurosci Methods, 364, 109371
DOI 10.1016/j.jneumeth.2021.109371, PubMed 34592173
Dimethyl fumarate does not mitigate cognitive decline and β-amyloidosis in female APPPS1 mice
Brain Res, 1768, 147579
DOI 10.1016/j.brainres.2021.147579, PubMed 34233173
Scaffold fragmentation and substructure hopping reveal potential, robustness, and limits of computer-aided pattern analysis (C@PA)
Comput Struct Biotechnol J, 19, 3269-3283
DOI 10.1016/j.csbj.2021.05.018, PubMed 34141145
C@PA: Computer-Aided Pattern Analysis to Predict Multitarget ABC Transporter Inhibitors
J Med Chem, 64 (6), 3350-3366
DOI 10.1021/acs.jmedchem.0c02199, PubMed 33724808
Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics
Comput Struct Biotechnol J, 19, 6490-6504
DOI 10.1016/j.csbj.2021.11.035, PubMed 34976306
Strategies to gain novel Alzheimer's disease diagnostics and therapeutics using modulators of ABCA transporters
Free Neuropathol, 2
DOI 10.17879/freeneuropathology-2021-3528, PubMed 34977908
Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin
Cancer Med, 10 (23), 8604-8613
DOI 10.1002/cam4.4334, PubMed 34612023
A New Tool for the Analysis of the Effect of Intracerebrally Injected Anti-Amyloid-β Compounds
J Alzheimers Dis, 84 (4), 1677-1690
DOI 10.3233/JAD-215180, PubMed 34719500
Publications 2020
High-yield Production of Amyloid-β Peptide Enabled by a Customized Spider Silk Domain
Sci Rep, 10 (1), 235
DOI 10.1038/s41598-019-57143-x, PubMed 31937841
Fingolimod as a Treatment in Neurologic Disorders Beyond Multiple Sclerosis
Drugs R D, 20 (3), 197-207
DOI 10.1007/s40268-020-00316-1, PubMed 32696271
Evaluating β-amyloidosis progression in Alzheimer's disease with Mueller polarimetry
Biomed Opt Express, 11 (8), 4509-4519
DOI 10.1364/BOE.396294, PubMed 32923060
The use of Stokes-Mueller polarimetry for assessment of amyloid-beta progression in a mouse model of Alzheimer's disease
PROC SPIE, 11234, 112340M
DOI 10.1117/12.2550795
Cut-off values for sufficient cortisol response to low dose Short Synacthen Test after surgery for non-functioning pituitary adenoma
Acta Neurochir (Wien), 162 (4), 845-852
DOI 10.1007/s00701-019-04068-z, PubMed 31907611
Using a qPCR device to screen for modulators of ABC transporter activity: A step-by-step protocol
J Pharmacol Toxicol Methods, 104, 106882
DOI 10.1016/j.vascn.2020.106882, PubMed 32474136
Detection and Prediction of Mild Cognitive Impairment in Alzheimer's Disease Mice
J Alzheimers Dis, 77 (3), 1209-1221
DOI 10.3233/JAD-200675, PubMed 32831204
Early Cognitive Training Rescues Remote Spatial Memory but Reduces Cognitive Flexibility in Alzheimer's Disease Mice
J Alzheimers Dis, 75 (4), 1301-1317
DOI 10.3233/JAD-200161, PubMed 32417783
Brain Distribution of Dual ABCB1/ABCG2 Substrates Is Unaltered in a Beta-Amyloidosis Mouse Model
Int J Mol Sci, 21 (21)
DOI 10.3390/ijms21218245, PubMed 33153231
Publications 2019
Generation and Characterization of an Abcc1 Humanized Mouse Model (hABCC1flx/flx ) with Knockout Capability
Mol Pharmacol, 96 (2), 138-147
DOI 10.1124/mol.119.115824, PubMed 31189668
Dynamic susceptibility contrast and diffusion MR imaging identify oligodendroglioma as defined by the 2016 WHO classification for brain tumors: histogram analysis approach
Neuroradiology, 61 (5), 545-555
DOI 10.1007/s00234-019-02173-5, PubMed 30712139
Imaging P-Glycoprotein Induction at the Blood-Brain Barrier of a β-Amyloidosis Mouse Model with 11C-Metoclopramide PET
J Nucl Med, 61 (7), 1050-1057
DOI 10.2967/jnumed.119.237198, PubMed 31806767
Measurement of cerebral ABCC1 transport activity in wild-type and APP/PS1-21 mice with positron emission tomography
J Cereb Blood Flow Metab, 40 (5), 954-965
DOI 10.1177/0271678X19854541, PubMed 31195936
Influence of Multidrug Resistance-Associated Proteins on the Excretion of the ABCC1 Imaging Probe 6-Bromo-7-[11C]Methylpurine in Mice
Mol Imaging Biol, 21 (2), 306-316
DOI 10.1007/s11307-018-1230-y, PubMed 29942989
Publications 2018
Age-related ultrastructural changes of the basement membrane in the mouse blood-brain barrier
J Cell Mol Med, 23 (2), 819-827
DOI 10.1111/jcmm.13980, PubMed 30450815
Intrinsic Xenobiotic Resistance of the Intestinal Stem Cell Niche
Dev Cell, 46 (6), 681-695.e5
DOI 10.1016/j.devcel.2018.07.023, PubMed 30146480
Humanization of the Blood-Brain Barrier Transporter ABCB1 in Mice Disrupts Genomic Locus - Lessons from Three Unsuccessful Approaches
Eur J Microbiol Immunol (Bp), 8 (3), 78-86
DOI 10.1556/1886.2018.00008, PubMed 30345087
ABCA7 Downregulation Modifies Cellular Cholesterol Homeostasis and Decreases Amyloid-β Peptide Efflux in an in vitro Model of the Blood-Brain Barrier
J Alzheimers Dis, 64 (4), 1195-1211
DOI 10.3233/JAD-170883, PubMed 30010117
Survival Associations Using Perfusion and Diffusion Magnetic Resonance Imaging in Patients With Histologic and Genetic Defined Diffuse Glioma World Health Organization Grades II and III
J Comput Assist Tomogr, 42 (5), 807-815
DOI 10.1097/RCT.0000000000000742, PubMed 29901512
K27/G34 versus K28/G35 in histone H3-mutant gliomas: A note of caution
Acta Neuropathol, 136 (1), 175-176
DOI 10.1007/s00401-018-1867-2, PubMed 29766298
Influence of breast cancer resistance protein and P-glycoprotein on tissue distribution and excretion of Ko143 assessed with PET imaging in mice
Eur J Pharm Sci, 115, 212-222
DOI 10.1016/j.ejps.2018.01.034, PubMed 29360507
Short-Term Effects of Microglia-Specific Mitochondrial Dysfunction on Amyloidosis in Transgenic Models of Alzheimer's Disease
J Alzheimers Dis, 65 (2), 465-474
DOI 10.3233/JAD-180395, PubMed 30040730
The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM
Brain Behav Immun, 73, 21-33
DOI 10.1016/j.bbi.2018.07.017, PubMed 30041013
Age dependency of cerebral P-glycoprotein function in wild-type and APPPS1 mice measured with PET
J Cereb Blood Flow Metab, 40 (1), 150-162
DOI 10.1177/0271678X18806640, PubMed 30354871
Publications 2017
Structural studies of amyloid-β peptides: Unlocking the mechanism of aggregation and the associated toxicity
Biochimie, 140, 176-192
DOI 10.1016/j.biochi.2017.07.011, PubMed 28751216
Improved method for cannula fixation for long-term intracerebral brain infusion
J Neurosci Methods, 290, 145-150
DOI 10.1016/j.jneumeth.2017.07.026, PubMed 28754434
Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice
Acta Neuropathol Commun, 5 (1), 49
DOI 10.1186/s40478-017-0448-2, PubMed 28637503
Publications 2016
Morphometric analysis of the cerebral expression of ATP-binding cassette transporter protein ABCB1 in chronic schizophrenia: Circumscribed deficits in the habenula
Schizophr Res, 177 (1-3), 52-58
DOI 10.1016/j.schres.2016.02.036, PubMed 26948503
Sideritis spp. Extracts Enhance Memory and Learning in Alzheimer's β-Amyloidosis Mouse Models and Aged C57Bl/6 Mice
J Alzheimers Dis, 53 (3), 967-80
DOI 10.3233/JAD-160301, PubMed 27258424
The choroid plexus in health and in disease: dialogues into and out of the brain
Neurobiol Dis, 107, 32-40
DOI 10.1016/j.nbd.2016.08.011, PubMed 27546055
Chronic Toxoplasma gondii infection enhances β-amyloid phagocytosis and clearance by recruited monocytes
Acta Neuropathol Commun, 4, 25
DOI 10.1186/s40478-016-0293-8, PubMed 26984535
Revisiting rodent models: Octodon degus as Alzheimer's disease model?
Acta Neuropathol Commun, 4 (1), 91
DOI 10.1186/s40478-016-0363-y, PubMed 27566602
Publications 2015
Perfusion single photon emission computed tomography in a mouse model of neurofibromatosis type 1: towards a biomarker of neurologic deficits
J Cereb Blood Flow Metab, 35 (8), 1304-12
DOI 10.1038/jcbfm.2015.43, PubMed 25785829
Suppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington's Disease
PLoS Genet, 11 (8), e1005267
DOI 10.1371/journal.pgen.1005267, PubMed 26247199
Activation of Mitochondrial Complex II-Dependent Respiration Is Beneficial for α-Synucleinopathies
Mol Neurobiol, 53 (7), 4728-44
DOI 10.1007/s12035-015-9399-4, PubMed 26319560
Accumulation of murine amyloid-β mimics early Alzheimer's disease
Brain, 138 (Pt 8), 2370-82
DOI 10.1093/brain/awv137, PubMed 25991605
The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease
Alzheimers Dement, 11 (12), 1407-1416
DOI 10.1016/j.jalz.2014.12.009, PubMed 25936935
Factors Governing P-Glycoprotein-Mediated Drug-Drug Interactions at the Blood-Brain Barrier Measured with Positron Emission Tomography
Mol Pharm, 12 (9), 3214-25
DOI 10.1021/acs.molpharmaceut.5b00168, PubMed 26202880
Publications 2014
Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary
Mech Ageing Dev, 141-142, 12-21
DOI 10.1016/j.mad.2014.08.003, PubMed 25218792
Nerve conduction velocity is regulated by the inositol polyphosphate-4-phosphatase II gene
Am J Pathol, 184 (9), 2420-9
DOI 10.1016/j.ajpath.2014.05.021, PubMed 25129256
Cerebral ABC transporter-common mechanisms may modulate neurodegenerative diseases and depression in elderly subjects
Arch Med Res, 45 (8), 738-43
DOI 10.1016/j.arcmed.2014.10.010, PubMed 25446622
Alzheimer's and ABC transporters--new opportunities for diagnostics and treatment
Neurobiol Dis, 72 Pt A, 54-60
DOI 10.1016/j.nbd.2014.04.001, PubMed 24746857
Publications 2013
Genomic background-related activation of microglia and reduced β-amyloidosis in a mouse model of Alzheimer's disease
Eur J Microbiol Immunol (Bp), 3 (1), 21-27
DOI 10.1556/EuJMI.3.2013.1.3, PubMed 23814667
Reduced Alzheimer's disease pathology by St. John's Wort treatment is independent of hyperforin and facilitated by ABCC1 and microglia activation in mice
Curr Alzheimer Res, 10 (10), 1057-69
DOI 10.2174/15672050113106660171, PubMed 24156265
Impaired mitochondrial energy production and ABC transporter function-A crucial interconnection in dementing proteopathies of the brain
Mech Ageing Dev, 134 (10), 506-15
DOI 10.1016/j.mad.2013.08.007, PubMed 24012632
DNp73 exerts function in metastasis initiation by disconnecting the inhibitory role of EPLIN on IGF1R-AKT/STAT3 signaling
Cancer Cell, 24 (4), 512-27
DOI 10.1016/j.ccr.2013.08.023, PubMed 24135282
Publications 2012
Intrathecal large granular lymphocytes as an unusual presentation of a small cell T cell lymphoma
Clin Neurol Neurosurg, 114 (7), 1102-3
DOI 10.1016/j.clineuro.2012.02.029, PubMed 22421252
Mitochondrial DNA polymorphisms specifically modify cerebral β-amyloid proteostasis
Acta Neuropathol, 124 (2), 199-208
DOI 10.1007/s00401-012-0980-x, PubMed 22526016
A novel sialyl Le(X) expression score as a potential prognostic tool in colorectal cancer
World J Surg Oncol, 10, 95
DOI 10.1186/1477-7819-10-95, PubMed 22621806
Efficient near-infrared in vivo imaging of amyoid-β deposits in Alzheimer's disease mouse models
J Alzheimers Dis, 30 (3), 651-64
DOI 10.3233/JAD-2012-112168, PubMed 22460331
ABC transporters B1, C1 and G2 differentially regulate neuroregeneration in mice
PLoS One, 7 (4), e35613
DOI 10.1371/journal.pone.0035613, PubMed 22545122
Publications 2011
No evidence for THAP1/DYT6 variants as disease modifiers in DYT1 dystonia
Mov Disord, 26 (11), 2136-7
DOI 10.1002/mds.23777, PubMed 21638323
Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice
J Clin Invest, 121 (10), 3924-31
DOI 10.1172/JCI57867, PubMed 21881209
Determination of spatial and temporal distribution of microglia by 230nm-high-resolution, high-throughput automated analysis reveals different amyloid plaque populations in an APP/PS1 mouse model of Alzheimer's disease
Curr Alzheimer Res, 8 (7), 781-8
DOI 10.2174/156720511797633179, PubMed 21244350
Development of Alzheimer-disease neuroimaging-biomarkers using mouse models with amyloid-precursor protein-transgene expression
Prog Neurobiol, 95 (4), 547-56
DOI 10.1016/j.pneurobio.2011.05.004, PubMed 21601614
Automated detection of amyloid-β-related cortical and subcortical signal changes in a transgenic model of Alzheimer's disease using high-field MRI
J Alzheimers Dis, 23 (2), 221-37
DOI 10.3233/JAD-2010-101035, PubMed 20966552
Publications 2010
Periphilin is a novel interactor of synphilin-1, a protein implicated in Parkinson's disease
Neurogenetics, 11 (2), 203-15
DOI 10.1007/s10048-009-0215-z, PubMed 19730898
Publications 2009
E2F1 in melanoma progression and metastasis
J Natl Cancer Inst, 102 (2), 127-33
DOI 10.1093/jnci/djp458, PubMed 20026813
Functionally relevant domains of the prion protein identified in vivo
PLoS One, 4 (9), e6707
DOI 10.1371/journal.pone.0006707, PubMed 19738901
Alzheimer's disease and blood-brain barrier function-Why have anti-beta-amyloid therapies failed to prevent dementia progression?
Neurosci Biobehav Rev, 33 (7), 1099-108
DOI 10.1016/j.neubiorev.2009.05.006, PubMed 19481107
In vivo 1H-magnetic resonance spectroscopy can detect metabolic changes in APP/PS1 mice after donepezil treatment
BMC Neurosci, 10, 33
DOI 10.1186/1471-2202-10-33, PubMed 19351388
Publications 2008
Outcome of very low birthweight infants after introducing a new standard regime with the early use of nasal CPAP
Eur J Pediatr, 167 (8), 909-16
DOI 10.1007/s00431-007-0646-1, PubMed 18172681
Clinico-pathologic function of cerebral ABC transporters - implications for the pathogenesis of Alzheimer's disease
Curr Alzheimer Res, 5 (4), 396-405
DOI 10.2174/156720508785132262, PubMed 18690837
Publications 2007
Lethal recessive myelin toxicity of prion protein lacking its central domain
EMBO J, 26 (2), 538-47
DOI 10.1038/sj.emboj.7601510, PubMed 17245436
Cholestasis from malignant melanoma
J Clin Oncol, 25 (6), 725-6
DOI 10.1200/JCO.2006.09.6230, PubMed 17308277
Deep brain stimulation in a rat model modulates TH, CaMKIIa and Homer1 gene expression
Eur J Neurosci, 25 (1), 239-50
DOI 10.1111/j.1460-9568.2006.05264.x, PubMed 17241285
2-DE profiling of GDNF overexpression-related proteome changes in differentiating ST14A rat progenitor cells
Proteomics, 7 (1), 33-46
DOI 10.1002/pmic.200600614, PubMed 17146836
The proteasomal subunit S6 ATPase is a novel synphilin-1 interacting protein--implications for Parkinson's disease
FASEB J, 21 (8), 1759-67
DOI 10.1096/fj.06-6734com, PubMed 17327361
Uptake of 18F-Fluorocholine, 18F-FET, and 18F-FDG in C6 gliomas and correlation with 131I-SIP(L19), a marker of angiogenesis
J Nucl Med, 48 (4), 608-14
DOI 10.2967/jnumed.106.036251, PubMed 17401099
Publications 2006
2-DE proteome analysis of a proliferating and differentiating human neuronal stem cell line (ReNcell VM)
Proteomics, 6 (6), 1833-47
DOI 10.1002/pmic.200500556, PubMed 16475233
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor Atorvastatin mediated effects depend on the activation status of target cells in PLP-EAE
J Autoimmun, 27 (4), 251-65
DOI 10.1016/j.jaut.2006.09.006, PubMed 17085013
Uptake of 18F-fluorocholine, 18F-fluoro-ethyl-L: -tyrosine and 18F-fluoro-2-deoxyglucose in F98 gliomas in the rat
Eur J Nucl Med Mol Imaging, 33 (6), 673-82
DOI 10.1007/s00259-005-0045-7, PubMed 16538503
Radioimmunotherapy targeting the extra domain B of fibronectin in C6 rat gliomas: a preliminary study about the therapeutic efficacy of iodine-131-labeled SIP(L19)
Nucl Med Biol, 33 (5), 661-6
DOI 10.1016/j.nucmedbio.2006.05.001, PubMed 16843841
Uncoupling protein 2 has protective function during experimental autoimmune encephalomyelitis
Am J Pathol, 168 (5), 1570-5
DOI 10.2353/ajpath.2006.051069, PubMed 16651623
Publications 2005
Identification of quantitative trait loci controlling cortical motor evoked potentials in experimental autoimmune encephalomyelitis: correlation with incidence, onset and severity of disease
Hum Mol Genet, 14 (14), 1977-89
DOI 10.1093/hmg/ddi203, PubMed 15917267
Collection of soluble variants of membrane proteins for transcriptomics and proteomics
In Silico Biol, 5 (3), 295-311
PubMed 15984938
Prevalence of Fabry disease in patients with cryptogenic stroke: a prospective study
Lancet, 366 (9499), 1794-6
DOI 10.1016/S0140-6736(05)67635-0, PubMed 16298216
Publications 2004
Gene-expression profiling of the early stages of MOG-induced EAE proves EAE-resistance as an active process
J Neuroimmunol, 151 (1-2), 158-70
DOI 10.1016/j.jneuroim.2004.03.007, PubMed 15145614
Overexpression of glial cell line-derived neurotrophic factor induces genes regulating migration and differentiation of neuronal progenitor cells
Exp Cell Res, 297 (2), 484-94
DOI 10.1016/j.yexcr.2004.03.037, PubMed 15212950
Wnt-5a expression in the rat neuronal progenitor cell line ST14A
Exp Brain Res, 158 (2), 189-95
DOI 10.1007/s00221-004-1887-0, PubMed 15309358
Uptake of 18F-fluorocholine, 18F-fluoroethyl-L-tyrosine, and 18F-FDG in acute cerebral radiation injury in the rat: implications for separation of radiation necrosis from tumor recurrence
J Nucl Med, 45 (11), 1931-8
PubMed 15534065
An impaired neocortical Ih is associated with enhanced excitability and absence epilepsy
Eur J Neurosci, 19 (11), 3048-58
DOI 10.1111/j.0953-816X.2004.03392.x, PubMed 15182313
The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease
Curr Alzheimer Res, 1 (2), 121-5
DOI 10.2174/1567205043332225, PubMed 15975076
Publications 2003
Gene expression profiling of ciliary neurotrophic factor-overexpressing rat striatal progenitor cells (ST14A) indicates improved stress response during the early stage of differentiation
J Neurosci Res, 73 (1), 42-53
DOI 10.1002/jnr.10624, PubMed 12815707
Expressionview: visualization of quantitative trait loci and gene-expression data in Ensembl
Genome Biol, 4 (11), R77
DOI 10.1186/gb-2003-4-11-r77, PubMed 14611663
McLeod phenotype associated with a XK missense mutation without hematologic, neuromuscular, or cerebral involvement
Transfusion, 43 (7), 928-38
DOI 10.1046/j.1537-2995.2003.t01-1-00434.x, PubMed 12823753
Publications 2002
Gene-expression profiling of experimental autoimmune encephalomyelitis
Neurochem Res, 27 (10), 1157-63
DOI 10.1023/a:1020925425780, PubMed 12462414
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