Institute for Cancer Research
Institute for Cancer Research has since its foundation in 1954 played a central role within the field of cancer research both in Norway and internationally. The Institute has seven research departments and more than 320 employees, master students included. About 70% of the employees and projects are externally funded.
The Institute has internationally strong research groups within biochemistry, cell and tumor biology, genetics, radiation biology, immunology and cancer prevention. For more than 30 years there has been a close interaction between researchers at the Institute and cancer surgeons, oncologists and pathologists. This emphasis on translational science has resulted in numerous clinical protocols based on in-house research, and the Institute is a key partner in the Comprehensive Cancer Center, organizationally under the Division of Surgery and Cancer Treatment at Oslo University Hospital.
Scientific production - Institute for Cancer Research
Annual report 2015 (pdf format)
The classical view of tissue macrophages is that they are continuously replaced by blood monocytes, but a paper first-authored by Ibon Eguiluz-Gracia (photo) from Frode Jahnsen's group at the Department of Pathology at OUH and the Centre for Immune Regulation at UiO, recently published in Thorax (journal impact factor 8.3), show that human alveolar macrophages are self-maintained within the lungs for many years. This may be important for development of chronic graft rejection, which is a common complication after lung transplantation and remains the major obstacle to better long-term outcomes.
Furthermore, as pointed out in the accompanying Editorial in Thorax, this study has potential implications for treatment of patients with alveolar proteinosis and COPD.
The board of the Norwegian Cancer Society will October 24th decide which research projects that will be funded. All applications have been peer reviewed internationally. Those receiving funding will be contacted prior to the event.
The announcement event take place on Friday October 28th at 10-10 AM in the "Professorboligen" at the University of Oslo. There will be talks held by a scientist, a fund-raiser, and a personal story will be told. There will also be an artistic peformance, and refreshments will be served.
Final date for registration: October 25th
Mouldy Sioud (photo) from the Department of Immunology at the Instiute for Cancer Research is senior author on an article recently published in Oncotarget (journal impact factor 6.36), entitled "Cancer cell-binding peptide fused Fc domain activates immune effector cells and blocks tumor growth".
Lina Prasmickaite from the Department of Tumor Biology at the Institute for Cancer Research has spent several years studying why certain cancer cells become immune against treatment. Her research on this subject is presented in a popular science article (in Norwegian) recently published by the Norwegian Cancer Society.
Welcome to the next Oslo University Hospital (OUH) research seminar entitled "Medical imaging in cardiac research".
Time: Monday, October 10th, 2016, at 14:30 – 16:00.
Place: Green Auditorium, Rikshospitalet, Sognsvannsveien 20, Oslo.
Speakers: Ivar Sjaastad, Emil Espe, Einar Hopp, Thor Edvardsen and Espen Remme.
The Norwegian Cancer Society have recently published a popular science article (in Norwegian) presenting the work of Gunhild Mælandsmo and Kjersti Flatmark, both from the Department of Tumor Biology at the Institute for Cancer Research. The scientists explains how their research on colorectal cancer may improve the methods of personalized medicine, and how the MetAction study, which is supported by the Norwegian Cancer Society, may contribute to the development of more precise cancer treatments in the future.
Oct 26, 2016
Oct 26, 2016
Oct 26, 2016
Announcement of research funding from the Norwegian Cancer Society
Oct 20, 2016
Inst. for Cancer Research
Evaluation of CD146 as Target for Radioimmunotherapy against Osteosarcoma
PLoS One, 11 (10), e0165382
Deep Pelvic Surgical Site Infection After Radiotherapy and Surgery for Locally Advanced Rectal Cancer
Ann Surg Oncol (in press)
Data including GROMACS input files for atomistic molecular dynamics simulations of mixed, asymmetric bilayers including molecular topologies, equilibrated structures, and force field for lipids compatible with OPLS-AA parameters
Data Brief, 7, 1171-1174
Journal Impact Factor > 5, first or last author from the Institute for Cancer Research