Institute for Cancer Research

 

Institute for Cancer Research has since its foundation in 1954 played a central role within the field of cancer research both in Norway and internationally. The Institute has seven research departments and more than 320 employees, master students included. About 70% of the employees and projects are externally funded.

The Institute has internationally strong research groups within biochemistry, cell and tumor biology, genetics, radiation biology, immunology and cancer prevention. For more than 30 years there has been a close interaction between researchers at the Institute and cancer surgeons, oncologists and pathologists. This emphasis on translational science has resulted in numerous clinical protocols based on in-house research, and the Institute is a key partner in the Comprehensive Cancer Center, organizationally under the Division of Surgery and Cancer Treatment at Oslo University Hospital.

Gunnar Sæter<br>Scientific director
Gunnar Sæter
Scientific director

Scientific production - Institute for Cancer Research

  Publications Doctoral theses
2015 so far  
2014 197  
2013 199 27
2012 175 18
2011 201 22
2010 221 11
2009 182 21
2008 152 11

Department overview

 

Latest news

Oslo University Hospital research seminar Monday April 20th 14:30-16

Proteomics: breakthroughs and cutting edge applications in immunology, microbiology, and cancer

 

Everyone is welcome to the next Oslo University Hospital research seminar, which is entitled "Personalized medicine". Speakers will be Gustavo de Souza, Siri Dørum, Wolfgang M. Egge-Jacobsen and Bernd Thiede. Meeting’s organizer and chairman is Nils Tore Vethe

Time: Monday, April 20th, 2015, at 14:30-16:00.
Place: Red Auditorium, Rikshospitalet, Sognsvannsveien 20, Oslo.

 
 

Nature article from Camilla Raiborg: Formation of cellular protrusions

 
Camilla Raiborg with last author Harald Stenmark
Camilla Raiborg with last author Harald Stenmark

In a recent paper in Nature (journal impact factor 42), project leader Camilla Raiborg and her co-workers in Harald Stenmark´s group at Institute for Cancer Research and Centre for Cancer Biomedicine show an unexpected connection between endosomes (organelles involved in protein import into cells) and the endoplasmic reticulum (ER, organelle involved in protein export) in formation of cellular protrusions.
EMBO journal has already published a commentary article about the findings, entitled "A grab to move on: ER–endosome contacts in membrane protrusion formation and neurite outgrowth".
The well visited Norwegian popular science website forskning.no has also published an article about the findings, entitled "The secrets of neurone protrusion formation revealed".

 
 

Oslo University Hospital has awarded 6 excellent articles for the second half-year of 2014

 
Award winners during ceremony
Award winners during ceremony

Oslo University Hospital has rewarded six research groups for their excellent papers published during the second half-year of 2014. Each group receives NOK 50.000 for use in further research. The prizes were distributed during the Friday meeting at Ullevål April 17th.
The award winners gave short presentations of the main findings in their respective articles. 

The six selected articles are of especially high quality, and they present important finding on both-short and long-term scales. The works reflect the good quality and the interdisciplinarity that characterises several research environments at Oslo University Hospital. The research is a fundamental condition for the institution to maintain and strenghten the quality in the patient treatment.

 
 

Article from Jorrit Enserink's group in "Genome research":

Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes

 
First author Chymkowitch (left) and Jorrit Enserink
First author Chymkowitch (left) and Jorrit Enserink

Sumo is a small protein that is attached to other proteins to regulate their function. A major class of Sumo targets are transcription factors. However, it is not well known which transcription factors are sumoylated, how sumoylation of these proteins is regulated, and how Sumo controls their function.

To begin unraveling the function of Sumo in transcription, Chymkowitch et al first determined at which genes Sumo can be detected. The results are recently published in the prestigious journal Genome research (impact factor 13.9) with Pierre Chymkowitch and Jorrit Enserink from the Department of Microbiology at the Department of Diagnostics and Invention as first and last authors respectively.

 
 

Fridtjof Nansen awards for excellent research to Anne-Lise Børresen-Dale and Jan Terje Andersen

 

The Fridtjof Nansen's award for excellent molecular cancer research goes to Anne-Lise Børresen-Dale from the Department of Genetics at the Institue for Cancer Research, OUH for the year of 2015.
The Fridtjof Nansen award for young researchers goes to Jan Terje Andersen from the Department of Immunology at the Division of Diagnostics and Intervention, OUH. He is also associated with the Centre for Immune Regulation (CIR).
The awards will be distributed during the annual meeting for  The Norwegian Academy of Science and Letters at Grand hotel Monday May 4th.

 
 

The Losby conference on personalized cancer treatment

 

The conference was organised March 11-12th by the National Priority Area of Cancer Research, a perennial initiative led by the Norwegian Radium Hospital, Oslo University Hospital. The chair for the conference was professor Ragnhild A. Lothe from the Department of Molecular Oncology, the Norwegian Radium Hospital, OUH, together with professor Per Eystein Lønning at Haukeland University Hospital.

The conference was organized for the second consecutive year and aims to make the path shorter from research to clinic. Young oncologists were especially invited to the conference this year. Presentation videos are now available (see More).