Welcome to the home page of Anne Simonsen's group Autophagy

Dysfunctional autophagy is linked to several pathophysiological conditions, including cancer and neurodegenerative disorders.⁠ The main focus of the “Simonsen Lab” is to characterize of the molecular mechanisms involved in cargo sequestration and autophagosome biogenesis during non-selective and selective types of autophagy with a long-term goal to identify novel targets for diagnosis or treatment of human disease.

The Simonsen Research Group
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About the group
Work in our laboratory is currently focused on identification of novel lipid-binding proteins involved in different types of autophagy and elucidation of their function in autophagy and link to disease. To address these challenges, we use a combination of cell biological, biochemical, imaging, genomic and computational approaches, as well as disease-related model systems.

 

 

Research Projects

Our research is funded by

  • The University of Oslo
  • The Research Council of Norway
  • The Norwegian Cancer Society
  • H-2020 MSC COFUND and ITN actions

Contact information:
Department of Molecular Cell Biology, Institute for Cancer Research
The Norwegian Radium Hospital, Montebello, N-0379 Oslo, Norway
Telephone +47 22 78 19 30 (Simonsen), +47 22 78 12 70 (Dept. Secretary)
Email: a.g.simonsen@medisin.uio.no