Publications by Anne Gjøen Simonsen

140 publications found

  1. Wang HL, Siow R, Schmauck-Medina T, Zhang J, Sandset PM, Filshie C, Lund Ø, Partridge L, Bergersen LH, Juel Rasmussen L, Palikaras K, Sotiropoulos I, Storm-Mathisen J, Rubinsztein DC, Spillantini MG, De Zeeuw CI, Watne LO, Vyhnalek M, Veverova K, Liang KX, Tavernarakis N, Bohr VA, Yokote K, Saarela J, Nilsen H et al. (2024)
    Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies
    J Gerontol A Biol Sci Med Sci, 79 (4)
    DOI 10.1093/gerona/glae029, PubMed 38289789
  2. Theriot JA, Simonsen A, Tolić I, Leonetti MD, Mayor S, Bassereau P, Paluch EK, Han J, Covert MW, Mizushima N, Reck-Peterson S, Strasser A, Cheeseman I (2024)
    Cell biology is…
    Cell, 187 (2), 219-224
    DOI 10.1016/j.cell.2023.12.020, PubMed 38242078
  3. Reggiori F, Boya P, da Costa D, Elazar Z, Eskelinen EL, Farrés J, Guettler S, Kraft C, Jungbluth H, Martinez A, Morel E, Pless O, Proikas-Cezanne T, Simonsen A (2022)
    The mechanism of macroautophagy: The movie
    Autophagy Rep, 1 (1), 414-417
    DOI 10.1080/27694127.2022.2096115, PubMed 38106995
  4. Sporbeck K, Haas ML, Pastor-Maldonado CJ, Schüssele DS, Hunter C, Takacs Z, Diogo de Oliveira AL, Franz-Wachtel M, Charsou C, Pfisterer SG, Gubas A, Haller PK, Knorr RL, Kaulich M, Macek B, Eskelinen EL, Simonsen A, Proikas-Cezanne T (2023)
    The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension
    Commun Biol, 6 (1), 872
    DOI 10.1038/s42003-023-05236-9, PubMed 37620393
  5. Kaur N, de la Ballina LR, Haukaas HS, Torgersen ML, Radulovic M, Munson MJ, Sabirsh A, Stenmark H, Simonsen A, Carlsson SR, Lystad AH (2023)
    TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy
    EMBO J, 42 (17), e113105
    DOI 10.15252/embj.2022113105, PubMed 37409525
  6. Rahman MA, Engelsen AST, Sarowar S, Bindesbøll C, Birkeland E, Goplen D, Lotsberg ML, Knappskog S, Simonsen A, Chekenya M (2022)
    Bortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway
    Front Cell Dev Biol, 10, 1022191
    DOI 10.3389/fcell.2022.1022191, PubMed 36619857
  7. Ganley IG, Simonsen A (2022)
    Diversity of mitophagy pathways at a glance
    J Cell Sci, 135 (23)
    DOI 10.1242/jcs.259748, PubMed 36504076
  8. Charsou C, Ng MYW, Simonsen A (2022)
    Regulation of autophagosome biogenesis and mitochondrial bioenergetics by the cholesterol transport protein GRAMD1C
    Autophagy, 19 (7), 2159-2161
    DOI 10.1080/15548627.2022.2155020, PubMed 36469687
  9. Maestro I, de la Ballina LR, Porras G, Corrochano S, De Lago E, Simonsen A, Boya P, Martinez A (2022)
    Discovery of Mitophagy Inhibitors with Therapeutic Potential in Different Familial Amyotrophic Lateral Sclerosis Mutations
    Int J Mol Sci, 23 (20)
    DOI 10.3390/ijms232012676, PubMed 36293534
  10. Ng MYW, Charsou C, Lapao A, Singh S, Trachsel-Moncho L, Schultz SW, Nakken S, Munson MJ, Simonsen A (2022)
    The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
    Nat Commun, 13 (1), 6283
    DOI 10.1038/s41467-022-33933-2, PubMed 36270994
  11. Simonsen A, Wollert T (2022)
    Don't forget to be picky - selective autophagy of protein aggregates in neurodegenerative diseases
    Curr Opin Cell Biol, 75, 102064
    DOI 10.1016/j.ceb.2022.01.009, PubMed 35240373
  12. Xu J, Yang KC, Go NE, Colborne S, Ho CJ, Hosseini-Beheshti E, Lystad AH, Simonsen A, Guns ET, Morin GB, Gorski SM (2022)
    Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations
    Autophagy, 18 (11), 2547-2560
    DOI 10.1080/15548627.2022.2039535, PubMed 35220892
  13. Sikkeland J, Ng MYW, Nenseth HZ, Unal B, Qu S, Jin Y, Simonsen A, Saatcioglu F (2022)
    STAMP2 suppresses autophagy in prostate cancer cells by modulating the integrated stress response pathway
    Am J Cancer Res, 12 (1), 327-336
    PubMed 35141021
  14. Søreng K, Pankiv S, Bergsmark C, Haugsten EM, Dahl AK, de la Ballina LR, Yamamoto A, Lystad AH, Simonsen A (2022)
    ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration
    J Cell Sci, 135 (4)
    DOI 10.1242/jcs.259138, PubMed 35099014
  15. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Simonsen A (2022)
    GAK and PRKCD kinases regulate basal mitophagy
    Autophagy, 18 (2), 467-469
    DOI 10.1080/15548627.2021.2015154, PubMed 35001811
  16. Cable J, Weber-Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, Chang C, Ge L, Schulman BA, Deshaies RJ, Dikic I, Harper JW, Wertz IE, Thomä NH, Słabicki M, Frydman J et al. (2022)
    Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report
    Ann N Y Acad Sci, 1510 (1), 79-99
    DOI 10.1111/nyas.14745, PubMed 35000205
  17. Sharma K, Asp NT, Harrison S, Siller R, Baumgarten SF, Gupta S, Chollet ME, Andersen E, Sullivan GJ, Simonsen A (2021)
    Autophagy modulates cell fate decisions during lineage commitment
    Autophagy, 18 (8), 1915-1931
    DOI 10.1080/15548627.2021.2008691, PubMed 34923909
  18. Aman Y, Schmauck-Medina T, Hansen M, Morimoto RI, Simon AK, Bjedov I, Palikaras K, Simonsen A, Johansen T, Tavernarakis N, Rubinsztein DC, Partridge L, Kroemer G, Labbadia J, Fang EF (2021)
    Autophagy in healthy aging and disease
    Nat Aging, 1 (8), 634-650
    DOI 10.1038/s43587-021-00098-4, PubMed 34901876
  19. Maestro I, de la Ballina LR, Simonsen A, Boya P, Martinez A (2021)
    Phenotypic Assay Leads to Discovery of Mitophagy Inducers with Therapeutic Potential for Parkinson's Disease
    ACS Chem Neurosci, 12 (24), 4512-4523
    DOI 10.1021/acschemneuro.1c00529, PubMed 34846852
  20. Kumar S, Javed R, Mudd M, Pallikkuth S, Lidke KA, Jain A, Tangavelou K, Gudmundsson SR, Ye C, Rusten TE, Anonsen JH, Lystad AH, Claude-Taupin A, Simonsen A, Salemi M, Phinney B, Li J, Guo LW, Bradfute SB, Timmins GS, Eskelinen EL, Deretic V (2021)
    Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes
    Cell, 184 (24), 5950-5969.e22
    DOI 10.1016/j.cell.2021.10.017, PubMed 34741801
  21. Giovannucci TA, Salomons FA, Stoy H, Herzog LK, Xu S, Qian W, Merino LG, Gierisch ME, Haraldsson M, Lystad AH, Uvell H, Simonsen A, Gustavsson AL, Vallin M, Dantuma NP (2021)
    Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy
    Autophagy, 18 (7), 1486-1502
    DOI 10.1080/15548627.2021.1988359, PubMed 34740308
  22. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A (2021)
    GAK and PRKCD are positive regulators of PRKN-independent mitophagy
    Nat Commun, 12 (1), 6101
    DOI 10.1038/s41467-021-26331-7, PubMed 34671015
  23. Klionsky DJ, Petroni G, Amaravadi RK, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cadwell K, Cecconi F, Choi AMK, Choi ME, Chu CT, Codogno P, Colombo MI, Cuervo AM, Deretic V, Dikic I, Elazar Z, Eskelinen EL, Fimia GM, Gewirtz DA, Green DR, Hansen M, Jäättelä M, Johansen T et al. (2021)
    Autophagy in major human diseases
    EMBO J, 40 (19), e108863
    DOI 10.15252/embj.2021108863, PubMed 34459017
  24. Durgan J, Lystad AH, Sloan K, Carlsson SR, Wilson MI, Marcassa E, Ulferts R, Webster J, Lopez-Clavijo AF, Wakelam MJ, Beale R, Simonsen A, Oxley D, Florey O (2021)
    Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine
    Mol Cell, 81 (9), 2031-2040.e8
    DOI 10.1016/j.molcel.2021.03.020, PubMed 33909989
  25. Ng MYW, Wai T, Simonsen A (2021)
    Quality control of the mitochondrion
    Dev Cell, 56 (7), 881-905
    DOI 10.1016/j.devcel.2021.02.009, PubMed 33662258
  26. Terešak P, Lapao A, Subic N, Boya P, Elazar Z, Simonsen A (2021)
    Regulation of PRKN-independent mitophagy
    Autophagy, 18 (1), 24-39
    DOI 10.1080/15548627.2021.1888244, PubMed 33570005
  27. Corkery DP, Nadeem A, Aung KM, Hassan A, Liu T, Cervantes-Rivera R, Lystad AH, Wang H, Persson K, Puhar A, Simonsen A, Uhlin BE, Wai SN, Wu YW (2021)
    Vibrio cholerae cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy
    J Cell Sci, 134 (5)
    DOI 10.1242/jcs.252015, PubMed 33106317
  28. Melia TJ, Lystad AH, Simonsen A (2020)
    Autophagosome biogenesis: From membrane growth to closure
    J Cell Biol, 219 (6)
    DOI 10.1083/jcb.202002085, PubMed 32357219
  29. Bindesbøll C, Aas A, Ogmundsdottir MH, Pankiv S, Reine T, Zoncu R, Simonsen A (2020)
    NBEAL1 controls SREBP2 processing and cholesterol metabolism and is a susceptibility locus for coronary artery disease
    Sci Rep, 10 (1), 4528
    DOI 10.1038/s41598-020-61352-0, PubMed 32161285
  30. Lotsberg ML, Wnuk-Lipinska K, Terry S, Tan TZ, Lu N, Trachsel-Moncho L, Røsland GV, Siraji MI, Hellesøy M, Rayford A, Jacobsen K, Ditzel HJ, Vintermyr OK, Bivona TG, Minna J, Brekken RA, Baguley B, Micklem D, Akslen LA, Gausdal G, Simonsen A, Thiery JP, Chouaib S, Lorens JB, Engelsen AST (2020)
    AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells
    J Thorac Oncol, 15 (6), 973-999
    DOI 10.1016/j.jtho.2020.01.015, PubMed 32018052
  31. Gawel K, Turski WA, van der Ent W, Mathai BJ, Kirstein-Smardzewska KJ, Simonsen A, Esguerra CV (2019)
    Phenotypic Characterization of Larval Zebrafish (Danio rerio) with Partial Knockdown of the cacna1a Gene
    Mol Neurobiol, 57 (4), 1904-1916
    DOI 10.1007/s12035-019-01860-x, PubMed 31875924
  32. Simonsen A, Sánchez-Heredia JD, Saarinen SA, Ardenkjær-Larsen JH, Schliesser A, Polzik ES (2019)
    Magnetic resonance imaging with optical preamplification and detection
    Sci Rep, 9 (1), 18173
    DOI 10.1038/s41598-019-54200-3, PubMed 31796770
  33. Herhaus L, Bhaskara RM, Lystad AH, Gestal-Mato U, Covarrubias-Pinto A, Bonn F, Simonsen A, Hummer G, Dikic I (2019)
    TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease
    EMBO Rep, 21 (1), e48317
    DOI 10.15252/embr.201948317, PubMed 31709703
  34. Herzog LK, Kevei É, Marchante R, Böttcher C, Bindesbøll C, Lystad AH, Pfeiffer A, Gierisch ME, Salomons FA, Simonsen A, Hoppe T, Dantuma NP (2019)
    The Machado-Joseph disease deubiquitylase ataxin-3 interacts with LC3C/GABARAP and promotes autophagy
    Aging Cell, 19 (1), e13051
    DOI 10.1111/acel.13051, PubMed 31625269
  35. Lystad AH, Simonsen A (2019)
    Mechanisms and Pathophysiological Roles of the ATG8 Conjugation Machinery
    Cells, 8 (9)
    DOI 10.3390/cells8090973, PubMed 31450711
  36. Rahman MA, Gras Navarro A, Brekke J, Engelsen A, Bindesbøll C, Sarowar S, Bahador M, Bifulco E, Goplen D, Waha A, Lie SA, Gjertsen BT, Selheim F, Enger PØ, Simonsen A, Chekenya M (2019)
    Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival
    Br J Cancer, 121 (7), 545-555
    DOI 10.1038/s41416-019-0551-1, PubMed 31413318
  37. Zhen Y, Spangenberg H, Munson MJ, Brech A, Schink KO, Tan KW, Sørensen V, Wenzel EM, Radulovic M, Engedal N, Simonsen A, Raiborg C, Stenmark H (2019)
    ESCRT-mediated phagophore sealing during mitophagy
    Autophagy, 16 (5), 826-841
    DOI 10.1080/15548627.2019.1639301, PubMed 31366282
  38. Gras Navarro A, Espedal H, Joseph JV, Trachsel-Moncho L, Bahador M, Gjertsen BT, Kristoffersen EK, Simonsen A, Miletic H, Enger PØ, Rahman MA, Chekenya M (2019)
    Pretreatment of Glioblastoma with Bortezomib Potentiates Natural Killer Cell Cytotoxicity through TRAIL/DR5 Mediated Apoptosis and Prolongs Animal Survival
    Cancers (Basel), 11 (7)
    DOI 10.3390/cancers11070996, PubMed 31319548
  39. Abudu YP, Pankiv S, Mathai BJ, Lamark T, Johansen T, Simonsen A (2019)
    NIPSNAP1 and NIPSNAP2 act as "eat me" signals to allow sustained recruitment of autophagy receptors during mitophagy
    Autophagy, 15 (10), 1845-1847
    DOI 10.1080/15548627.2019.1637642, PubMed 31251109
  40. Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Liu M, Hall P, Sklar LA, Allers L, Mariscal L, Garcia SA, Weaver J, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, Eskelinen EL, Fourie B, Gozuacik D, Hong W, Jo EK, Johansen T et al. (2019)
    Autophagy, Inflammation, and Metabolism (AIM) Center in its second year
    Autophagy, 15 (10), 1829-1833
    DOI 10.1080/15548627.2019.1634444, PubMed 31234750
  41. de la Ballina LR, Munson MJ, Simonsen A (2019)
    Lipids and Lipid-Binding Proteins in Selective Autophagy
    J Mol Biol, 432 (1), 135-159
    DOI 10.1016/j.jmb.2019.05.051, PubMed 31202884
  42. Lystad AH, Carlsson SR, Simonsen A (2019)
    Toward the function of mammalian ATG12-ATG5-ATG16L1 complex in autophagy and related processes
    Autophagy, 15 (8), 1485-1486
    DOI 10.1080/15548627.2019.1618100, PubMed 31122169
  43. Princely Abudu Y, Pankiv S, Mathai BJ, Håkon Lystad A, Bindesbøll C, Brenne HB, Yoke Wui Ng M, Thiede B, Yamamoto A, Mutugi Nthiga T, Lamark T, Esguerra CV, Johansen T, Simonsen A (2019)
    NIPSNAP1 and NIPSNAP2 Act as "Eat Me" Signals for Mitophagy
    Dev Cell, 49 (4), 509-525.e12
    DOI 10.1016/j.devcel.2019.03.013, PubMed 30982665
  44. Lystad AH, Carlsson SR, de la Ballina LR, Kauffman KJ, Nag S, Yoshimori T, Melia TJ, Simonsen A (2019)
    Distinct functions of ATG16L1 isoforms in membrane binding and LC3B lipidation in autophagy-related processes
    Nat Cell Biol, 21 (3), 372-383
    DOI 10.1038/s41556-019-0274-9, PubMed 30778222
  45. Chaurasia M, Gupta S, Das A, Dwarakanath BS, Simonsen A, Sharma K (2019)
    Radiation induces EIF2AK3/PERK and ERN1/IRE1 mediated pro-survival autophagy
    Autophagy, 15 (8), 1391-1406
    DOI 10.1080/15548627.2019.1582973, PubMed 30773986
  46. Möller K, Sigurbjornsdottir S, Arnthorsson AO, Pogenberg V, Dilshat R, Fock V, Brynjolfsdottir SH, Bindesboll C, Bessadottir M, Ogmundsdottir HM, Simonsen A, Larue L, Wilmanns M, Thorsson V, Steingrimsson E, Ogmundsdottir MH (2019)
    MITF has a central role in regulating starvation-induced autophagy in melanoma
    Sci Rep, 9 (1), 1055
    DOI 10.1038/s41598-018-37522-6, PubMed 30705290
  47. Ogmundsdottir MH, Fock V, Sooman L, Pogenberg V, Dilshat R, Bindesbøll C, Ogmundsdottir HM, Simonsen A, Wilmanns M, Steingrimsson E (2018)
    Publisher Correction: A short isoform of ATG7 fails to lipidate LC3/GABARAP
    Sci Rep, 8 (1), 17194
    DOI 10.1038/s41598-018-35540-y, PubMed 30446765
  48. Johannessen TC, Hasan-Olive MM, Zhu H, Denisova O, Grudic A, Latif MA, Saed H, Varughese JK, Røsland GV, Yang N, Sundstrøm T, Nordal A, Tronstad KJ, Wang J, Lund-Johansen M, Simonsen A, Janji B, Westermarck J, Bjerkvig R, Prestegarden L (2018)
    Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide
    Int J Cancer, 144 (7), 1735-1745
    DOI 10.1002/ijc.31912, PubMed 30289977
  49. Ogmundsdottir MH, Fock V, Sooman L, Pogenberg V, Dilshat R, Bindesbøll C, Ogmundsdottir HM, Simonsen A, Wilmanns M, Steingrimsson E (2018)
    A short isoform of ATG7 fails to lipidate LC3/GABARAP
    Sci Rep, 8 (1), 14391
    DOI 10.1038/s41598-018-32694-7, PubMed 30258106
  50. Kraft C, Boya P, Codogno P, Elazar Z, Eskelinen EL, Farrés J, Kirkin V, Jungbluth H, Martinez A, Pless O, Primard C, Proikas-Cezanne T, Simonsen A, Reggiori F (2018)
    Driving next-generation autophagy researchers towards translation (DRIVE), an international PhD training program on autophagy
    Autophagy, 15 (2), 347-351
    DOI 10.1080/15548627.2018.1515532, PubMed 30176150
  51. Simonsen A (2018)
    Confidence to go the way science takes you
    Nat Cell Biol, 20 (9), 1009
    DOI 10.1038/s41556-018-0156-6, PubMed 30154563
  52. Skah S, Richartz N, Duthil E, Gilljam KM, Bindesbøll C, Naderi EH, Eriksen AB, Ruud E, Dirdal MM, Simonsen A, Blomhoff HK (2018)
    cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53
    Oncotarget, 9 (54), 30434-30449
    DOI 10.18632/oncotarget.25758, PubMed 30100998
  53. Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Sklar LA, Allers L, Garcia SA, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, Eskelinen EL, Fourie B, Gozuacik D, Hong W, Hotamisligi G, Jäättelä M, Jo EK, Johansen T, Juhász G, Kimchi A et al. (2018)
    Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations
    Autophagy, 14 (6), 925-929
    DOI 10.1080/15548627.2018.1465784, PubMed 29938597
  54. SenGupta T, Torgersen ML, Kassahun H, Vellai T, Simonsen A, Nilsen H (2018)
    Publisher Correction: Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy
    Nat Commun, 9, 16206
    DOI 10.1038/ncomms16206, PubMed 29595188
  55. Søreng K, Munson MJ, Lamb CA, Bjørndal GT, Pankiv S, Carlsson SR, Tooze SA, Simonsen A (2018)
    SNX18 regulates ATG9A trafficking from recycling endosomes by recruiting Dynamin-2
    EMBO Rep, 19 (4)
    DOI 10.15252/embr.201744837, PubMed 29437695
  56. Søreng K, Neufeld TP, Simonsen A (2017)
    Membrane Trafficking in Autophagy
    Int Rev Cell Mol Biol, 336, 1-92
    DOI 10.1016/bs.ircmb.2017.07.001, PubMed 29413888
  57. Schläfli AM, Isakson P, Garattini E, Simonsen A, Tschan MP (2017)
    The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells
    Sci Rep, 7 (1), 12980
    DOI 10.1038/s41598-017-12734-4, PubMed 29021535
  58. Kjos I, Borg Distefano M, Sætre F, Repnik U, Holland P, Jones AT, Engedal N, Simonsen A, Bakke O, Progida C (2017)
    Rab7b modulates autophagic flux by interacting with Atg4B
    EMBO Rep, 18 (10), 1727-1739
    DOI 10.15252/embr.201744069, PubMed 28835545
  59. Mathai BJ, Meijer AH, Simonsen A (2017)
    Studying Autophagy in Zebrafish
    Cells, 6 (3)
    DOI 10.3390/cells6030021, PubMed 28698482
  60. Galluzzi L, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cecconi F, Choi AM, Chu CT, Codogno P, Colombo MI, Cuervo AM, Debnath J, Deretic V, Dikic I, Eskelinen EL, Fimia GM, Fulda S, Gewirtz DA, Green DR, Hansen M, Harper JW, Jäättelä M, Johansen T, Juhasz G, Kimmelman AC et al. (2017)
    Molecular definitions of autophagy and related processes
    EMBO J, 36 (13), 1811-1836
    DOI 10.15252/embj.201796697, PubMed 28596378
  61. Søreng K, Knævelsrud H, Holland P, Simonsen A (2017)
    HS1BP3 inhibits autophagy by regulation of PLD1
    Autophagy, 13 (5), 985-986
    DOI 10.1080/15548627.2017.1291483, PubMed 28318354
  62. Aas A, Isakson P, Bindesbøll C, Alemu EA, Klungland A, Simonsen A (2017)
    Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy
    PLoS One, 12 (3), e0168182
    DOI 10.1371/journal.pone.0168182, PubMed 28288181
  63. Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A (2016)
    HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels
    Nat Commun, 7, 13889
    DOI 10.1038/ncomms13889, PubMed 28004827
  64. Simonsen A (2016)
    [Self-devouring prolongs life]
    Tidsskr Nor Laegeforen, 136 (22), 1873
    DOI 10.4045/tidsskr.16.0908, PubMed 27929545
  65. Dragich JM, Kuwajima T, Hirose-Ikeda M, Yoon MS, Eenjes E, Bosco JR, Fox LM, Lystad AH, Oo TF, Yarygina O, Mita T, Waguri S, Ichimura Y, Komatsu M, Simonsen A, Burke RE, Mason CA, Yamamoto A (2016)
    Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain
    Elife, 5
    DOI 10.7554/eLife.14810, PubMed 27648578
  66. Shatz O, Holland P, Elazar Z, Simonsen A (2016)
    Complex Relations Between Phospholipids, Autophagy, and Neutral Lipids
    Trends Biochem Sci, 41 (11), 907-923
    DOI 10.1016/j.tibs.2016.08.001, PubMed 27595473
  67. Lystad AH, Simonsen A (2016)
    Phosphoinositide-binding proteins in autophagy
    FEBS Lett, 590 (15), 2454-68
    DOI 10.1002/1873-3468.12286, PubMed 27391591
  68. Andersen AN, Landsverk OJ, Simonsen A, Bogen B, Corthay A, Øynebråten I (2016)
    Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity
    Front Immunol, 7, 167
    DOI 10.3389/fimmu.2016.00167, PubMed 27242780
  69. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM et al. (2016)
    Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
    Autophagy, 12 (1), 1-222
    DOI 10.1080/15548627.2015.1100356, PubMed 26799652
  70. Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M (2016)
    ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors
    Sci Signal, 9 (411), ra8
    DOI 10.1126/scisignal.aad0848, PubMed 26787452
  71. Ylä-Anttila P, Mikkonen E, Happonen KE, Holland P, Ueno T, Simonsen A, Eskelinen EL (2015)
    RAB24 facilitates clearance of autophagic compartments during basal conditions
    Autophagy, 11 (10), 1833-48
    DOI 10.1080/15548627.2015.1086522, PubMed 26325487
  72. Holland P, Simonsen A (2015)
    Actin shapes the autophagosome
    Nat Cell Biol, 17 (9), 1094-6
    DOI 10.1038/ncb3224, PubMed 26316454
  73. Hieke N, Löffler AS, Kaizuka T, Berleth N, Böhler P, Drießen S, Stuhldreier F, Friesen O, Assani K, Schmitz K, Peter C, Diedrich B, Dengjel J, Holland P, Simonsen A, Wesselborg S, Mizushima N, Stork B (2015)
    Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells
    Autophagy, 11 (9), 1471-83
    DOI 10.1080/15548627.2015.1068488, PubMed 26213203
  74. Drießen S, Berleth N, Friesen O, Löffler AS, Böhler P, Hieke N, Stuhldreier F, Peter C, Schink KO, Schultz SW, Stenmark H, Holland P, Simonsen A, Wesselborg S, Stork B (2015)
    Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy
    Autophagy, 11 (9), 1458-70
    DOI 10.1080/15548627.2015.1067359, PubMed 26207339
  75. Eriksen AB, Torgersen ML, Holm KL, Abrahamsen G, Spurkland A, Moskaug JØ, Simonsen A, Blomhoff HK (2015)
    Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy
    Autophagy, 11 (3), 460-71
    DOI 10.1080/15548627.2015.1009797, PubMed 25749095
  76. Galluzzi L, Pietrocola F, Bravo-San Pedro JM, Amaravadi RK, Baehrecke EH, Cecconi F, Codogno P, Debnath J, Gewirtz DA, Karantza V, Kimmelman A, Kumar S, Levine B, Maiuri MC, Martin SJ, Penninger J, Piacentini M, Rubinsztein DC, Simon HU, Simonsen A, Thorburn AM, Velasco G, Ryan KM, Kroemer G (2015)
    Autophagy in malignant transformation and cancer progression
    EMBO J, 34 (7), 856-80
    DOI 10.15252/embj.201490784, PubMed 25712477
  77. Carlsson SR, Simonsen A (2015)
    Membrane dynamics in autophagosome biogenesis
    J Cell Sci, 128 (2), 193-205
    DOI 10.1242/jcs.141036, PubMed 25568151
  78. Lystad AH, Simonsen A (2014)
    Assays to monitor aggrephagy
    Methods, 75, 112-9
    DOI 10.1016/j.ymeth.2014.12.019, PubMed 25555675
  79. Holland P, Torgersen ML, Sandvig K, Simonsen A (2014)
    LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis
    Traffic, 15 (12), 1390-405
    DOI 10.1111/tra.12227, PubMed 25216107
  80. Mandell MA, Jain A, Arko-Mensah J, Chauhan S, Kimura T, Dinkins C, Silvestri G, Münch J, Kirchhoff F, Simonsen A, Wei Y, Levine B, Johansen T, Deretic V (2014)
    TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition
    Dev Cell, 30 (4), 394-409
    DOI 10.1016/j.devcel.2014.06.013, PubMed 25127057
  81. Lystad AH, Ichimura Y, Takagi K, Yang Y, Pankiv S, Kanegae Y, Kageyama S, Suzuki M, Saito I, Mizushima T, Komatsu M, Simonsen A (2014)
    Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures
    EMBO Rep, 15 (5), 557-65
    DOI 10.1002/embr.201338003, PubMed 24668264
  82. Bagci T, Simonsen A, Schmid S, Villanueva LG, Zeuthen E, Appel J, Taylor JM, Sørensen A, Usami K, Schliesser A, Polzik ES (2014)
    Optical detection of radio waves through a nanomechanical transducer
    Nature, 507 (7490), 81-5
    DOI 10.1038/nature13029, PubMed 24598636
  83. SenGupta T, Torgersen ML, Kassahun H, Vellai T, Simonsen A, Nilsen H (2013)
    Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy
    Nat Commun, 4, 2674
    DOI 10.1038/ncomms3674, PubMed 24154628
  84. Torgersen ML, Simonsen A (2013)
    Autophagy: friend or foe in the treatment of fusion protein-associated leukemias?
    Autophagy, 9 (12), 2175-7
    DOI 10.4161/auto.26559, PubMed 24145192
  85. Isakson P, Lystad AH, Breen K, Koster G, Stenmark H, Simonsen A (2013)
    TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy
    Autophagy, 9 (12), 1955-64
    DOI 10.4161/auto.26085, PubMed 24128730
  86. Knævelsrud H, Carlsson SR, Simonsen A (2013)
    SNX18 tubulates recycling endosomes for autophagosome biogenesis
    Autophagy, 9 (10), 1639-41
    DOI 10.4161/auto.26124, PubMed 24113029
  87. Torgersen ML, Engedal N, Bøe SO, Hokland P, Simonsen A (2013)
    Targeting autophagy potentiates the apoptotic effect of histone deacetylase inhibitors in t(8;21) AML cells
    Blood, 122 (14), 2467-76
    DOI 10.1182/blood-2013-05-500629, PubMed 23970379
  88. Engedal N, Torgersen ML, Guldvik IJ, Barfeld SJ, Bakula D, Sætre F, Hagen LK, Patterson JB, Proikas-Cezanne T, Seglen PO, Simonsen A, Mills IG (2013)
    Modulation of intracellular calcium homeostasis blocks autophagosome formation
    Autophagy, 9 (10), 1475-90
    DOI 10.4161/auto.25900, PubMed 23970164
  89. Knævelsrud H, Søreng K, Raiborg C, Håberg K, Rasmuson F, Brech A, Liestøl K, Rusten TE, Stenmark H, Neufeld TP, Carlsson SR, Simonsen A (2013)
    Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation
    J Cell Biol, 202 (2), 331-49
    DOI 10.1083/jcb.201205129, PubMed 23878278
  90. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A et al. (2012)
    Guidelines for the use and interpretation of assays for monitoring autophagy
    Autophagy, 8 (4), 445-544
    DOI 10.4161/auto.19496, PubMed 22966490
  91. Reggiori F, Komatsu M, Finley K, Simonsen A (2012)
    Selective types of autophagy
    Int J Cell Biol, 2012, 156272
    DOI 10.1155/2012/156272, PubMed 22956958
  92. Mijaljica D, Nazarko TY, Brumell JH, Huang WP, Komatsu M, Prescott M, Simonsen A, Yamamoto A, Zhang H, Klionsky DJ, Devenish RJ (2012)
    Receptor protein complexes are in control of autophagy
    Autophagy, 8 (11), 1701-5
    DOI 10.4161/auto.21332, PubMed 22874568
  93. Lång E, Grudic A, Pankiv S, Bruserud O, Simonsen A, Bjerkvig R, Bjørås M, Bøe SO (2012)
    The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling
    Blood, 120 (4), 847-57
    DOI 10.1182/blood-2011-10-388496, PubMed 22692509
  94. Reggiori F, Komatsu M, Finley K, Simonsen A (2012)
    Autophagy: more than a nonselective pathway
    Int J Cell Biol, 2012, 219625
    DOI 10.1155/2012/219625, PubMed 22666256
  95. Isakson P, Holland P, Simonsen A (2012)
    The role of ALFY in selective autophagy
    Cell Death Differ, 20 (1), 12-20
    DOI 10.1038/cdd.2012.66, PubMed 22653340
  96. Knævelsrud H, Simonsen A (2012)
    Lipids in autophagy: constituents, signaling molecules and cargo with relevance to disease
    Biochim Biophys Acta, 1821 (8), 1133-45
    DOI 10.1016/j.bbalip.2012.01.001, PubMed 22269166
  97. Klionsky DJ, Baehrecke EH, Brumell JH, Chu CT, Codogno P, Cuervo AM, Debnath J, Deretic V, Elazar Z, Eskelinen EL, Finkbeiner S, Fueyo-Margareto J, Gewirtz D, Jäättelä M, Kroemer G, Levine B, Melia TJ, Mizushima N, Rubinsztein DC, Simonsen A, Thorburn A, Thumm M, Tooze SA (2011)
    A comprehensive glossary of autophagy-related molecules and processes (2nd edition)
    Autophagy, 7 (11), 1273-94
    DOI 10.4161/auto.7.11.17661, PubMed 21997368
  98. Bartlett BJ, Isakson P, Lewerenz J, Sanchez H, Kotzebue RW, Cumming RC, Harris GL, Nezis IP, Schubert DR, Simonsen A, Finley KD (2011)
    p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects
    Autophagy, 7 (6), 572-83
    DOI 10.4161/auto.7.6.14943, PubMed 21325881
  99. Yamamoto A, Simonsen A (2011)
    Alfy-dependent elimination of aggregated proteins by macroautophagy: can there be too much of a good thing?
    Autophagy, 7 (3), 346-50
    DOI 10.4161/auto.7.3.14234, PubMed 21150266
  100. Yamamoto A, Simonsen A (2010)
    The elimination of accumulated and aggregated proteins: a role for aggrephagy in neurodegeneration
    Neurobiol Dis, 43 (1), 17-28
    DOI 10.1016/j.nbd.2010.08.015, PubMed 20732422
  101. Knævelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA, Simonsen A (2010)
    UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
    Autophagy, 6 (7), 863-70
    DOI 10.4161/auto.6.7.13033, PubMed 20724836
  102. Bøe SO, Simonsen A (2010)
    Autophagic degradation of an oncoprotein
    Autophagy, 6 (7), 964-5
    DOI 10.4161/auto.6.7.13066, PubMed 20724820
  103. Isakson P, Bjørås M, Bøe SO, Simonsen A (2010)
    Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein
    Blood, 116 (13), 2324-31
    DOI 10.1182/blood-2010-01-261040, PubMed 20574048
  104. Filimonenko M, Isakson P, Finley KD, Anderson M, Jeong H, Melia TJ, Bartlett BJ, Myers KM, Birkeland HC, Lamark T, Krainc D, Brech A, Stenmark H, Simonsen A, Yamamoto A (2010)
    The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy
    Mol Cell, 38 (2), 265-79
    DOI 10.1016/j.molcel.2010.04.007, PubMed 20417604
  105. Knaevelsrud H, Simonsen A (2010)
    Fighting disease by selective autophagy of aggregate-prone proteins
    FEBS Lett, 584 (12), 2635-45
    DOI 10.1016/j.febslet.2010.04.041, PubMed 20412801
  106. Clausen TH, Lamark T, Isakson P, Finley K, Larsen KB, Brech A, Øvervatn A, Stenmark H, Bjørkøy G, Simonsen A, Johansen T (2010)
    p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
    Autophagy, 6 (3), 330-44
    DOI 10.4161/auto.6.3.11226, PubMed 20168092
  107. Simonsen A, Tooze SA (2009)
    Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
    J Cell Biol, 186 (6), 773-82
    DOI 10.1083/jcb.200907014, PubMed 19797076
  108. Cumming RC, Simonsen A, Finley KD (2008)
    Quantitative analysis of autophagic activity in Drosophila neural tissues by measuring the turnover rates of pathway substrates
    Methods Enzymol, 451, 639-51
    DOI 10.1016/S0076-6879(08)03235-7, PubMed 19185743
  109. Simonsen A, Stenmark H (2008)
    Self-eating from an ER-associated cup
    J Cell Biol, 182 (4), 621-2
    DOI 10.1083/jcb.200807061, PubMed 18725534
  110. Rusten TE, Simonsen A (2008)
    ESCRT functions in autophagy and associated disease
    Cell Cycle, 7 (9), 1166-72
    DOI 10.4161/cc.7.9.5784, PubMed 18418046
  111. Nezis IP, Simonsen A, Sagona AP, Finley K, Gaumer S, Contamine D, Rusten TE, Stenmark H, Brech A (2008)
    Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
    J Cell Biol, 180 (6), 1065-71
    DOI 10.1083/jcb.200711108, PubMed 18347073
  112. Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y et al. (2007)
    Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
    Autophagy, 4 (2), 151-75
    DOI 10.4161/auto.5338, PubMed 18188003
  113. Simonsen A, Cumming RC, Brech A, Isakson P, Schubert DR, Finley KD (2007)
    Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
    Autophagy, 4 (2), 176-84
    DOI 10.4161/auto.5269, PubMed 18059160
  114. Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher EM, Isaacs A, Brech A, Stenmark H, Simonsen A (2007)
    Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
    J Cell Biol, 179 (3), 485-500
    DOI 10.1083/jcb.200702115, PubMed 17984323
  115. Simonsen A, Cumming RC, Finley KD (2007)
    Linking lysosomal trafficking defects with changes in aging and stress response in Drosophila
    Autophagy, 3 (5), 499-501
    DOI 10.4161/auto.4604, PubMed 17617737
  116. Simonsen A, Stenmark H (2007)
    Stimulating the cell's appetite for itself
    Nat Chem Biol, 3 (6), 304-6
    DOI 10.1038/nchembio0607-304, PubMed 17510644
  117. Simonsen A, Cumming RC, Lindmo K, Galaviz V, Cheng S, Rusten TE, Finley KD (2007)
    Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles
    Genetics, 176 (2), 1283-97
    DOI 10.1534/genetics.106.065011, PubMed 17435236
  118. Norlén L, Gil IP, Simonsen A, Descouts P (2006)
    Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films
    J Struct Biol, 158 (3), 386-400
    DOI 10.1016/j.jsb.2006.12.006, PubMed 17287132
  119. Lindmo K, Simonsen A, Brech A, Finley K, Rusten TE, Stenmark H (2006)
    A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
    Exp Cell Res, 312 (11), 2018-27
    DOI 10.1016/j.yexcr.2006.03.002, PubMed 16600212
  120. Simonsen A, Birkeland HC, Gillooly DJ, Mizushima N, Kuma A, Yoshimori T, Slagsvold T, Brech A, Stenmark H (2004)
    Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
    J Cell Sci, 117 (Pt 18), 4239-51
    DOI 10.1242/jcs.01287, PubMed 15292400
  121. Kauppi M, Simonsen A, Bremnes B, Vieira A, Callaghan J, Stenmark H, Olkkonen VM (2002)
    The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking
    J Cell Sci, 115 (Pt 5), 899-911
    DOI 10.1242/jcs.115.5.899, PubMed 11870209
  122. Gillooly DJ, Simonsen A, Stenmark H (2001)
    Phosphoinositides and phagocytosis
    J Cell Biol, 155 (1), 15-7
    DOI 10.1083/jcb.200109001, PubMed 11581282
  123. Simonsen A, Stenmark H (2001)
    PX domains: attracted by phosphoinositides
    Nat Cell Biol, 3 (8), E179-82
    DOI 10.1038/35087112, PubMed 11483972
  124. Simonsen A, Wurmser AE, Emr SD, Stenmark H (2001)
    The role of phosphoinositides in membrane transport
    Curr Opin Cell Biol, 13 (4), 485-92
    DOI 10.1016/s0955-0674(00)00240-4, PubMed 11454456
  125. Gillooly DJ, Simonsen A, Stenmark H (2001)
    Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins
    Biochem J, 355 (Pt 2), 249-58
    DOI 10.1042/0264-6021:3550249, PubMed 11284710
  126. Gaullier JM, Gillooly D, Simonsen A, Stenmark H (1999)
    Regulation of endocytic membrane traffic by phosphatidylinositol 3-phosphate
    Biochem Soc Trans, 27 (4), 666-70
    DOI 10.1042/bst0270666, PubMed 10917663
  127. Simonsen A, Gaullier JM, D'Arrigo A, Stenmark H (1999)
    The Rab5 effector EEA1 interacts directly with syntaxin-6
    J Biol Chem, 274 (41), 28857-60
    DOI 10.1074/jbc.274.41.28857, PubMed 10506127
  128. Simonsen A, Pedersen KW, Nordeng TW, von der Lippe A, Stang E, Long EO, Bakke O (1999)
    Polarized transport of MHC class II molecules in Madin-Darby canine kidney cells is directed by a leucine-based signal in the cytoplasmic tail of the beta-chain
    J Immunol, 163 (5), 2540-8
    PubMed 10452991
  129. Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H (1999)
    FYVE finger proteins as effectors of phosphatidylinositol 3-phosphate
    Chem Phys Lipids, 98 (1-2), 87-94
    DOI 10.1016/s0009-3084(99)00021-3, PubMed 10358931
  130. Callaghan J, Simonsen A, Gaullier JM, Toh BH, Stenmark H (1999)
    The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer
    Biochem J, 338 ( Pt 2) (Pt 2), 539-43
    DOI 10.1042/0264-6021:3380539, PubMed 10024533
  131. Simonsen A, Lippé R, Christoforidis S, Gaullier JM, Brech A, Callaghan J, Toh BH, Murphy C, Zerial M, Stenmark H (1998)
    EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
    Nature, 394 (6692), 494-8
    DOI 10.1038/28879, PubMed 9697774
  132. Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H, Aasland R (1998)
    FYVE fingers bind PtdIns(3)P
    Nature, 394 (6692), 432-3
    DOI 10.1038/28767, PubMed 9697764
  133. Simonsen A, Bremnes B, Nordeng TW, Bakke O (1998)
    The leucine-based motif DDQxxLI is recognized both for internalization and basolateral sorting of invariant chain in MDCK cells
    Eur J Cell Biol, 76 (1), 25-32
    DOI 10.1016/S0171-9335(98)80014-9, PubMed 9650780
  134. Simonsen A, Bremnes B, Rønning E, Aasland R, Stenmark H (1998)
    Syntaxin-16, a putative Golgi t-SNARE
    Eur J Cell Biol, 75 (3), 223-31
    DOI 10.1016/S0171-9335(98)80116-7, PubMed 9587053
  135. Simonsen A, Stang E, Bremnes B, Røe M, Prydz K, Bakke O (1997)
    Sorting of MHC class II molecules and the associated invariant chain (Ii) in polarized MDCK cells
    J Cell Sci, 110 ( Pt 5), 597-609
    DOI 10.1242/jcs.110.5.597, PubMed 9092942
  136. Simonsen A, Momburg F, Drexler J, Hämmerling GJ, Bakke O (1993)
    Intracellular distribution of the MHC class II molecules and the associated invariant chain (Ii) in different cell lines
    Int Immunol, 5 (8), 903-17
    DOI 10.1093/intimm/5.8.903, PubMed 8398985
  137. Simonsen A, Voeltz GK (2012)
    Organelle biogenesis and autophagy
    Mol. Biol. Cell, 23 (6), 981
    DOI 10.1091/mbc.E11-12-0979
  138. Prosch-Danielsen L, Simonsen A (2000)
    Palaeoecological investigations towards the reconstruction of the history of forest clearances and coastal heathlands in south-western Norway
    Veg. Hist. Archaeobot., 9 (4), 189-204
    DOI 10.1007/BF01294634
  139. Storen T, Simonsen A, Royset AK, Lokberg OJ, Svaasand LO, Lindmo T (2003)
    Time resolved spectroscopic optical coherence tomography for diffusion measurements
    P SOC PHOTO-OPT INS, 4956, 197-204
    DOI 10.1117/12.477645
  140. Rusten TE, Filimonenko M, Rodahl LM, Stenmark H, Simonsen A (2008)
    ESCRTing autophagic clearance of aggregating proteins
    Autophagy, 4 (2), 233-236
    DOI 10.4161/auto.5396

 
Page visits: 1075