The research group focuses on research related to critical conditions for the brain and the heart, like cardiac arrest and traumatic brain injuries. We collaborate internationally and nationally and participate in multicenter RCTs. In addition, we do different clinical observation studies and register-based studies, where both short-and long-term outcome, and outcome with function, are being evaluated. Finally, we have an experimental pig model, where pigs after cardiac arrest, resuscitated with a Heart-Lung-Machine, are evaluated related to brain flow, ischaemic markers, and metabolism.

The research group aims to evaluate different aspects related to outcome and sequelae after critical conditions like cardiac arrest and severe traumatic brain injury. Both these life-threatening conditions require comprehensive intensive care treatment after initial resuscitation. We aim to investigate clinical factors impacting on outcome, and evaluate methods of prognostication among comatose, critically ill patients, both related to short- and long-term outcome. Long term cognitive function and quality of life among the survivors´ deservers also more attention, in addition to effects of early rehabilitation. With our experimental pig model, we aim to investigate and better understand the pathophysiology after cardiac arrest (both circulation and metabolism), and these studies are related to ongoing clinical studies or knowledge gaps around the same pathophysiological challenges
With this we hope to contribute to increased understanding, improved treatment and thereby better prognoses for these critically ill and vulnerable patient groups.

Link to Brain-Heart home page at UiO

Professor Kjetil Sunde, Dept of Anaesthesiology, Division of Emergencies and Critical Care, Oslo University Hospital
Mob 95224201   E.mail kjetil.sunde@medisin.uio.no