PCI of antibody based therapeutics
Current therapeutic use of antibodies is limited to antigens expressed on the cell surface or released into the circulation due to a lack of an effective mechanisms to access the inside of the cell.
In this project we aim to use the PCI method to obtain efficient cytosolic/nuclear delivery of antibodies having intracellular targets.
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The project is founded by Radforsk with a 3 years fellowship provided Weyergang