Light Meets Precision:
EIC Pathfinder Project SCALPEL Pioneering a Revolutionary Photoimmunotherapy for Cancer
Theo Theodossiou, Project coordinator
In a groundbreaking effort to revolutionise modern oncology, the SCALPEL project launches a Europe wide initiative aimed at redefining cancer treatment by using light to precisely ‘click’ tags to cancer cells, enabling the immune system to recognise and destroy them with unparalleled accuracy. Project coordinator is Theo Theodossiou, head of the Protonics project group at the Department of Radiation Biology at OUH.
The multidisciplinary initiative funded by the European Innovation Council Pathfinder programme under Horizon Europe with a total budget of more than EUR 4 million aims to revolutionise modern oncology offering new hope for millions worldwide.
Published in Level 2 journals, first or last author from Oslo University Hospital.
Kildal W, Pradhan M, Kristensen GB, Vlatkovic L, Tobin KAR, Hveem TS, Lindemann K, Askautrud HA, Kleppe A(2026) Prognostic role of estrogen receptor, L1 cell adhesion molecule, and tumor grade in patients with endometrial carcinoma of no specific molecular profile Int J Gynecol Cancer, 36(5), 104669(in press) DOI 10.1016/j.ijgc.2026.104669, PubMed 41990404
Myhre AE, Meyer-Myklestad MH, Gullaksen HH, Søgaard OS, Tolstrup M, Salgado M, Martinez-Picado J, Holberg-Petersen M, Juhl AK, Schleimann MH, Gunst JD, Thomsen A, Fisher K, Bhamra JS, Kran AB, Halvorsen B, Dyrhol-Riise AM, Reikvam DH, Aukrust P, Gedde-Dahl T, Oslo HIV Cure Study Group, Dahl TB, Kaarbø M, Trøseid M(2026) Long-term HIV-1 remission achieved through allogeneic haematopoietic stem cell transplant from a CCR5Δ32/Δ32 sibling donor Nat Microbiol(in press) DOI 10.1038/s41564-026-02304-8, PubMed 41975092
Noreng L, Øiestad ÅML, Hansen FA, Røberg-Larsen H, Wilson SR, Øiestad EL(2026) Toward Sustainable Clinical Analysis: Benchmarking Plastic Use in LC-MS Sample Preparation - Exemplified by Ketamine Analogues in Whole Blood Anal Chem(in press) DOI 10.1021/acs.analchem.5c08225, PubMed 41972595