Ieva Ailte

  • Postdoc; PhD
  • +47 22 78 18 66

The metastatic melanoma project group aims to identify biomarkers that allow us to stratify patients into those who benefit from immunotherapy and those who do not. Immunotherapy is a highly effective treatment for a subset of patients, but there are also many who do not respond to this therapy. It is additionally associated with significant side effects and late effects, and it is costly. Identifying patients who are unlikely to benefit from immunotherapy will spare them unnecessary treatment and the burden of side effects.

The MelMet project: Biomarkers in melanoma

Read more about melanoma research and networking at OUS here (in Norwegian only):
Melanoma Meet & Greet | Melanomforeningen

 

Publications 2021

Weisheit S, Wegner CS, Ailte I, Radulovic M, Weyergang A, Selbo PK, Brech A (2021)
Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy
Biochem Pharmacol, 194, 114837
DOI 10.1016/j.bcp.2021.114837, PubMed 34780750

Publications 2019

Sioud M, Pettersen S, Ailte I, Fløisand Y (2019)
Targeted Killing of Monocytes/Macrophages and Myeloid Leukemia Cells with Pro-Apoptotic Peptides
Cancers (Basel), 11 (8)
DOI 10.3390/cancers11081088, PubMed 31370273

Publications 2017

Ailte I, Lingelem AB, Kvalvaag AS, Kavaliauskiene S, Brech A, Koster G, Dommersnes PG, Bergan J, Skotland T, Sandvig K (2017)
Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
Traffic, 18 (3), 176-191
DOI 10.1111/tra.12468, PubMed 28067430

Publications 2016

Ailte I, Lingelem AB, Kavaliauskiene S, Bergan J, Kvalvaag AS, Myrann AG, Skotland T, Sandvig K (2016)
Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding
Sci Rep, 6, 30336
DOI 10.1038/srep30336, PubMed 27458147

Publications 2015

Dyve Lingelem AB, Hjelseth IA, Simm R, Torgersen ML, Sandvig K (2015)
Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells
PLoS One, 10 (5), e0129214
DOI 10.1371/journal.pone.0129214, PubMed 26017782

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