❭ Research by medical division ❭ Cancer Medicine ❭ Institute for Cancer Research ❭ Dept. of Tumor Biology ❭ G. Mælandsmo's group ❭ Research interests ❭

Our major areas of interest are:

Treatment Resistance and Metastasis-Involved Mechanisms

  • Cellular plasticity 
    • Breast cancer and melanoma
    • Prostate cancer
  • Metastasis-associated proteins
  • Immune checkpoint protein B7-H3 as novel therapeutic target in cancer

Word cloud from articles published by the group the past 10 years

Experimental Cancer Therapy

  • Nanoparticle-based drug delivery
  • Breast cancer
  • Prostate cancer

Precision Cancer Medicine

  • Clinical studies in breast cancer
  • Clinical studies in melanoma
  • Metaction
  • Biomarker studies in clinical cohorts
    • Breast cancer biomarkers
    • Biomarkers in melanoma
    • Brain metastasis
    • Prostate cancer biomarkers
 
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Home Dept. of Tumor Biology G. Mælandsmo's group

  • Group members
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Recent publications

Trnkova L, Burikova M, Soltysova A, Ficek A, Plava J, Cumova A, Rojikova L, Jakic K, Sedlackova E, Tichy B, Bystry V, Busato F, Shen Y, Matuskova M, Kucerova L, Øy GF, Mælandsmo GM, Fleischer T, Tost J, Miklikova S, Cihova M, Buocikova V, Smolkova B (2026)
Molecular profiling of chemotherapy-resistant breast cancer reveals DNA methylation remodeling associated with the acquisition of paclitaxel resistance
Drug Resist Updat, 85, 101350 (in press)
DOI 10.1016/j.drup.2026.101350, PubMed 41529624

Riaza Montes M, Suárez B, Solano-Iturri JD, Lecumberri D, Iturregui AM, Lawrie CH, Armesto M, Nunes-Xavier CE, Pulido R, López JI, Angulo JC, Larrinaga G (2025)
Fibroblast Activation Protein Alpha (FAP) Expression Is Associated with Disease Recurrence and Poor Response to Tyrosine Kinase Inhibitors in Advanced Clear Cell Renal Cell Carcinoma
Int J Mol Sci, 26 (22)
DOI 10.3390/ijms262211112, PubMed 41303595

Wang S, Santacana-Font G, Kedra D, Gilfillan S, Tena-Chaves D, Bergholtz H, Engebraaten O, Lingjaerde OC, Gutiérrez-Fernández J, Norum JH, Sørlie T, López-Aviles S, Hurtado A (2025)
The harmonized activities of HER2-HER3 heterodimer and deacetylated FOXA1 evade hormone response by regulating FOXA1 chromatin binding
Nucleic Acids Res, 53 (20)
DOI 10.1093/nar/gkaf1086, PubMed 41224124



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