Publications 2025

Andersen IL, Lukina P, Dyrli OT, Klaasen RA, Warren DJ, Bolstad N, Mjønes P, Rønne E, Iversen R, Sollid LM, Lundin KEA, Ness-Jensen E (2025)
Serological screening for coeliac disease in an adult general population: the HUNT study
Gut, 74 (6), 918-925
DOI 10.1136/gutjnl-2024-333886, PubMed 40011035

Iversen R, Heggelund JE, Das S, Høydahl LS, Sollid LM (2025)
Enzyme-activating B-cell receptors boost antigen presentation to pathogenic T cells in gluten-sensitive autoimmunity
Nat Commun, 16 (1), 2387
DOI 10.1038/s41467-025-57564-5, PubMed 40064932

Publications 2024

Das S, Stamnaes J, Høydahl LS, Skagen C, Lundin KEA, Jahnsen J, Sollid LM, Iversen R (2024)
Selective activation of naïve B cells with unique epitope specificity shapes autoantibody formation in celiac disease
J Autoimmun, 146, 103241
DOI 10.1016/j.jaut.2024.103241, PubMed 38754235

du Pre MF, Iversen R, Sollid LM (2024)
Coeliac disease: the paradox of diagnosing a food hypersensitivity disorder with autoantibodies
Gut, 73 (5), 844-853
DOI 10.1136/gutjnl-2023-331595, PubMed 38378252

Iversen R, Sollid LM (2024)
Dissecting autoimmune encephalitis through the lens of intrathecal B cells
Proc Natl Acad Sci U S A, 121 (9), e2401337121
DOI 10.1073/pnas.2401337121, PubMed 38354256

Lindeman I, Høydahl LS, Christophersen A, Risnes LF, Jahnsen J, Lundin KEA, Sollid LM, Iversen R (2024)
Generation of circulating autoreactive pre-plasma cells fueled by naive B cells in celiac disease
Cell Rep, 43 (4), 114045
DOI 10.1016/j.celrep.2024.114045, PubMed 38578826

Lukina P, Andersen IL, Eggen PT, Mjønes PG, Rønne E, Bolstad N, Klaasen RA, Warren DJ, Iversen R, Hveem K, Bernklev T, Jelsness-Jørgensen LP, Pedersen L, Jonkers I, Lagergren P, Sollid LM, Lundin K, Ness-Jensen E (2024)
Coeliac disease in the Trøndelag Health Study (HUNT), Norway, a population-based cohort of coeliac disease patients
BMJ Open, 14 (1), e077131
DOI 10.1136/bmjopen-2023-077131, PubMed 38195172

Lukina P, Andersen IL, Klaasen RA, Warren DJ, Bolstad N, Mjønes P, Rønne E, Iversen R, Sollid LM, Lundin KEA, Ness-Jensen E (2024)
The Prevalence and Rate of Undiagnosed Celiac Disease in an Adult General Population, the Trøndelag Health Study, Norway
Clin Gastroenterol Hepatol, 23 (7), 1143-1151
DOI 10.1016/j.cgh.2024.06.027, PubMed 38987013

Publications 2023

Das S, Stamnaes J, Kemppainen E, Hervonen K, Lundin KEA, Parmar N, Jahnsen FL, Jahnsen J, Lindfors K, Salmi T, Iversen R, Sollid LM (2023)
Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis
Adv Sci (Weinh), 10 (25), e2300401
DOI 10.1002/advs.202300401, PubMed 37424036

Heggelund JE, Das S, Stamnaes J, Iversen R, Sollid LM (2023)
Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3
Nat Commun, 14 (1), 6216
DOI 10.1038/s41467-023-42004-z, PubMed 37798283

Publications 2022

Iversen R, Sollid LM (2022)
The Immunobiology and Pathogenesis of Celiac Disease
Annu Rev Pathol, 18, 47-70
DOI 10.1146/annurev-pathmechdis-031521-032634, PubMed 36067801

Klaasen RA, Warren DJ, Iversen R, Bolstad N, Andersen IL, Mjønes P, Rønne E, Lundin KEA, Sollid LM, Ness-Jensen E (2022)
The development and validation of a high-capacity serological assay for celiac disease
Clin Biochem, 107, 13-18
DOI 10.1016/j.clinbiochem.2022.05.010, PubMed 35660483

Sollid LM, Iversen R (2022)
Tango of B cells with T cells in the making of secretory antibodies to gut bacteria
Nat Rev Gastroenterol Hepatol, 20 (2), 120-128
DOI 10.1038/s41575-022-00674-y, PubMed 36056203

Zhou C, Østerbye T, Bach E, Dahal-Koirala S, Høydahl LS, Steinsbø Ø, Jahnsen J, Lundin KEA, Buus S, Sollid LM, Iversen R (2022)
Focused B cell response to recurring gluten motif with implications for epitope spreading in celiac disease
Cell Rep, 41 (4), 111541
DOI 10.1016/j.celrep.2022.111541, PubMed 36288703

Publications 2021

Lindeman I, Zhou C, Eggesbø LM, Miao Z, Polak J, Lundin KEA, Jahnsen J, Qiao SW, Iversen R, Sollid LM (2021)
Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells
J Exp Med, 218 (2)
DOI 10.1084/jem.20200852, PubMed 33095260

Publications 2020

Iversen R, Amundsen SF, Kleppa L, du Pré MF, Stamnaes J, Sollid LM (2020)
Evidence That Pathogenic Transglutaminase 2 in Celiac Disease Derives From Enterocytes
Gastroenterology, 159 (2), 788-790
DOI 10.1053/j.gastro.2020.04.018, PubMed 32302613

Iversen R, Sollid LM (2020)
Autoimmunity provoked by foreign antigens
Science, 368 (6487), 132-133
DOI 10.1126/science.aay3037, PubMed 32273455

Publications 2019

Iversen R, Roy B, Stamnaes J, Høydahl LS, Hnida K, Neumann RS, Korponay-Szabó IR, Lundin KEA, Sollid LM (2019)
Efficient T cell-B cell collaboration guides autoantibody epitope bias and onset of celiac disease
Proc Natl Acad Sci U S A, 116 (30), 15134-15139
DOI 10.1073/pnas.1901561116, PubMed 31285344

Publications 2018

Høydahl LS, Richter L, Frick R, Snir O, Gunnarsen KS, Landsverk OJB, Iversen R, Jeliazkov JR, Gray JJ, Bergseng E, Foss S, Qiao SW, Lundin KEA, Jahnsen J, Jahnsen FL, Sandlie I, Sollid LM, Løset GÅ (2018)
Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease
Gastroenterology, 156 (5), 1428-1439.e10
DOI 10.1053/j.gastro.2018.12.013, PubMed 30593798

Publications 2017

Iversen R, Snir O, Stensland M, Kroll JE, Steinsbø Ø, Korponay-Szabó IR, Lundin KEA, de Souza GA, Sollid LM (2017)
Strong Clonal Relatedness between Serum and Gut IgA despite Different Plasma Cell Origins
Cell Rep, 20 (10), 2357-2367
DOI 10.1016/j.celrep.2017.08.036, PubMed 28877470

Roy B, Neumann RS, Snir O, Iversen R, Sandve GK, Lundin KEA, Sollid LM (2017)
High-Throughput Single-Cell Analysis of B Cell Receptor Usage among Autoantigen-Specific Plasma Cells in Celiac Disease
J Immunol, 199 (2), 782-791
DOI 10.4049/jimmunol.1700169, PubMed 28600290

Publications 2016

Cardoso I, Østerlund EC, Stamnaes J, Iversen R, Andersen JT, Jørgensen TJ, Sollid LM (2016)
Dissecting the interaction between transglutaminase 2 and fibronectin
Amino Acids, 49 (3), 489-500
DOI 10.1007/s00726-016-2296-y, PubMed 27394141

Hnida K, Stamnaes J, du Pré MF, Mysling S, Jørgensen TJ, Sollid LM, Iversen R (2016)
Epitope-dependent Functional Effects of Celiac Disease Autoantibodies on Transglutaminase 2
J Biol Chem, 291 (49), 25542-25552
DOI 10.1074/jbc.M116.738161, PubMed 27784785

Høydahl LS, Nilssen NR, Gunnarsen KS, Pré MF, Iversen R, Roos N, Chen X, Michaelsen TE, Sollid LM, Sandlie I, Løset GÅ (2016)
Multivalent pIX phage display selects for distinct and improved antibody properties
Sci Rep, 6, 39066
DOI 10.1038/srep39066, PubMed 27966617

Stamnaes J, Cardoso I, Iversen R, Sollid LM (2016)
Transglutaminase 2 strongly binds to an extracellular matrix component other than fibronectin via its second C-terminal beta-barrel domain
FEBS J, 283 (21), 3994-4010
DOI 10.1111/febs.13907, PubMed 27685605

Publications 2015

Cardoso I, Stamnaes J, Andersen JT, Melino G, Iversen R, Sollid LM (2015)
Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies
FEBS J, 282 (11), 2063-75
DOI 10.1111/febs.13276, PubMed 25808416

Chen X, Hnida K, Graewert MA, Andersen JT, Iversen R, Tuukkanen A, Svergun D, Sollid LM (2015)
Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease
J Biol Chem, 290 (35), 21365-75
DOI 10.1074/jbc.M115.669895, PubMed 26160175

Iversen R, Fleur du Pré M, Di Niro R, Sollid LM (2015)
Igs as Substrates for Transglutaminase 2: Implications for Autoantibody Production in Celiac Disease
J Immunol, 195 (11), 5159-68
DOI 10.4049/jimmunol.1501363, PubMed 26503953

Sollid LM, Iversen R, Steinsbø Ø, Qiao SW, Bergseng E, Dørum S, du Pré MF, Stamnaes J, Christophersen A, Cardoso I, Hnida K, Chen X, Snir O, Lundin KEA (2015)
Small bowel, celiac disease and adaptive immunity
Dig Dis, 33 (2), 115-121
DOI 10.1159/000369512, PubMed 25925911

Stamnaes J, Iversen R, du Pré MF, Chen X, Sollid LM (2015)
Enhanced B-Cell Receptor Recognition of the Autoantigen Transglutaminase 2 by Efficient Catalytic Self-Multimerization
PLoS One, 10 (8), e0134922
DOI 10.1371/journal.pone.0134922, PubMed 26244572

Publications 2014

Iversen R, Mysling S, Hnida K, Jørgensen TJ, Sollid LM (2014)
Activity-regulating structural changes and autoantibody epitopes in transglutaminase 2 assessed by hydrogen/deuterium exchange
Proc Natl Acad Sci U S A, 111 (48), 17146-51
DOI 10.1073/pnas.1407457111, PubMed 25404341

Publications 2013

Iversen R, Di Niro R, Stamnaes J, Lundin KE, Wilson PC, Sollid LM (2013)
Transglutaminase 2-specific autoantibodies in celiac disease target clustered, N-terminal epitopes not displayed on the surface of cells
J Immunol, 190 (12), 5981-91
DOI 10.4049/jimmunol.1300183, PubMed 23690478

Publications 2012

Di Niro R, Mesin L, Zheng NY, Stamnaes J, Morrissey M, Lee JH, Huang M, Iversen R, du Pré MF, Qiao SW, Lundin KE, Wilson PC, Sollid LM (2012)
High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions
Nat Med, 18 (3), 441-5
DOI 10.1038/nm.2656, PubMed 22366952

Qiao SW, Iversen R, Ráki M, Sollid LM (2012)
The adaptive immune response in celiac disease
Semin Immunopathol, 34 (4), 523-40
DOI 10.1007/s00281-012-0314-z, PubMed 22535446