Group members

Sowa ST, Kücükdisli M, Mostinski Y, Schaller DA, Vinagreiro CS, Cirillo D, Bosetti C, Brinch SA, van Laar K, Wegert A, Leenders RGG, Krauss S, Waaler J, Volkamer A, Lehtiö L, Nazaré M (2025)
Deconstruction of Dual-Site Tankyrase Inhibitors Provides Insights into Binding Energetics and Suggests Critical Hotspots for Ligand Optimization
J Med Chem (in press)
DOI 10.1021/acs.jmedchem.4c02845, PubMed 40134122

Bosetti C, Kampasis D, Brinch SA, Galera-Prat A, Karelou M, Dhakar SS, Alaviuhkola J, Waaler J, Lehtiö L, Kostakis IK (2025)
Substitutions at the C-8 position of quinazolin-4-ones improve the potency of nicotinamide site binding tankyrase inhibitors
Eur J Med Chem, 288, 117397
DOI 10.1016/j.ejmech.2025.117397, PubMed 39983556

Tse J, O'Keefe R, Rigopolous A, Carli ALE, Waaler J, Krauss S, Ernst M, Buchert M (2023)
A Mouse Model for the Rapid and Binomial Assessment of Putative WNT/β-Catenin Signalling Inhibitors
Biomedicines, 11 (10)
DOI 10.3390/biomedicines11102719, PubMed 37893093