Publications Department. of Tumor Biology

Publications published since 1971 from OUS - Department of Tumor Biology

1419 publications found (only first 1000 shown)

Publications 2024

1. Akdeniz BC, Frei O, Hagen E, Filiz TT, Karthikeyan S, Pasman J, Jangmo A, Bergstedt J, Shorter JR, Zetterberg R, Meijsen J, Sønderby IE, Buil A, Tesli M, Lu Y, Sullivan P, Andreassen OA, Hovig E (2024)
   COSGAP: COntainerized Statistical Genetics Analysis Pipelines
   Bioinform Adv, 4 (1), vbae067
   DOI 10.1093/bioadv/vbae067, PubMed 38808072
2. Akdeniz BC, Frei O, Shadrin A, Vetrov D, Kropotov D, Hovig E, Andreassen OA, Dale AM (2024)
   Finemap-MiXeR: A variational Bayesian approach for genetic finemapping
   PLoS Genet, 20 (8), e1011372
   DOI 10.1371/journal.pgen.1011372, PubMed 39146375
3. Akdeniz BC, Morris AH, Møller P, Andreassen O, Hovig E, Dominguez-Valentin M (2024)
   Evaluation of a combined model of Polygenic Risk Score and mismatch repair genes in the association of colorectal cancer for Norwegian cohort
   Tumori, 3008916241303648 (in press)
   DOI 10.1177/03008916241303648, PubMed 39654342
4. Angulo JC, Larrinaga G, Lecumberri D, Iturregui AM, Solano-Iturri JD, Lawrie CH, Armesto M, Dorado JF, Nunes-Xavier CE, Pulido R, Manini C, López JI (2024)
   Predicting Survival of Metastatic Clear Cell Renal Cell Cancer Treated with VEGFR-TKI-Based Sequential Therapy
   Cancers (Basel), 16 (16)
   DOI 10.3390/cancers16162786, PubMed 39199559
5. Bai B, Wise JF, Vodák D, Nakken S, Sharma A, Blaker YN, Brodtkorb M, Hilden V, Trøen G, Ren W, Lorenz S, Lawrence MS, Myklebost O, Kimby E, Pan-Hammarström Q, Steen CB, Meza-Zepeda LA, Beiske K, Smeland EB, Hovig E, Lingjærde OC, Holte H, Myklebust JH (2024)
   Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma
   Blood Cancer J, 14 (1), 147
   DOI 10.1038/s41408-024-01124-5, PubMed 39191762
6. Bischof K, Cremaschi A, Eroukhmanoff L, Landskron J, Flage-Larsen LL, Gade A, Bjørge L, Urbanucci A, Taskén K (2024)
   Patient-derived acellular ascites fluid affects drug responses in ovarian cancer cell lines through the activation of key signalling pathways
   Mol Oncol (in press)
   DOI 10.1002/1878-0261.13726, PubMed 39245677
7. Bucher-Johannessen C, Senthakumaran T, Avershina E, Birkeland E, Hoff G, Bemanian V, Tunsjø H, Rounge TB (2024)
   Species-level verification of Phascolarctobacterium association with colorectal cancer
   mSystems, 9 (10), e0073424
   DOI 10.1128/msystems.00734-24, PubMed 39287376
8. Cavanaugh D, Urbanucci A, Mohamed NE, Tewari AK, Figueiro M, Kyprianou N (2024)
   Link between circadian rhythm and benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS)
   Prostate, 84 (5), 417-425
   DOI 10.1002/pros.24656, PubMed 38193363
9. Clarke AW, Høye E, Hembrom AA, Paynter VM, Vinther J, Wyrożemski Ł, Biryukova I, Formaggioni A, Ovchinnikov V, Herlyn H, Pierce A, Wu C, Aslanzadeh M, Cheneby J, Martinez P, Friedländer MR, Hovig E, Hackenberg M, Umu SU, Johansen M, Peterson KJ, Fromm B (2024)
   MirGeneDB 3.0: improved taxonomic sampling, uniform nomenclature of novel conserved microRNA families and updated covariance models
   Nucleic Acids Res (in press)
   DOI 10.1093/nar/gkae1094, PubMed 39673268
10. Dagenborg VJ, Brudvik KW, Lund-Andersen C, Torgunrud A, Lund-Iversen M, Flatmark K, Larsen SG, Yaqub S (2024)
    Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy and Liver Resection is a Treatment Option for Patients With Peritoneal and Liver Metastases From Colorectal Cancer
    Ann Surg, 280 (5), 745-752
    DOI 10.1097/SLA.0000000000006492, PubMed 39185557
11. Davidson B, Holth A, Lindemann K, Zahl Eriksson AG, Nilsen TA, Torgunrud A (2024)
    Molecular characteristics of tubo-ovarian carcinosarcoma at different anatomic locations
    Virchows Arch, 485 (6), 1053-1061
    DOI 10.1007/s00428-024-03821-9, PubMed 38733380
12. Edsjö A, Russnes HG, Lehtiö J, Tamborero D, Hovig E, Stenzinger A, Rosenquist R, PCM4EU consortium (2024)
    High-throughput molecular assays for inclusion in personalised oncology trials - State-of-the-art and beyond
    J Intern Med, 295 (6), 785-803
    DOI 10.1111/joim.13785, PubMed 38698538
13. Egeland EV, Seip K, Skourti E, Øy GF, Pettersen SJ, Pandya AD, Dahle MA, Haugen MH, Kristian A, Nakken S, Engebraaten O, Mælandsmo GM, Prasmickaite L (2024)
    The SRC-family serves as a therapeutic target in triple negative breast cancer with acquired resistance to chemotherapy
    Br J Cancer, 131 (10), 1656-1667
    DOI 10.1038/s41416-024-02875-5, PubMed 39390250
14. Ellegaard MR, Ebenesersdóttir SS, Moore KHS, Petersén A, Vågene ÅJ, Bieker VC, Denham SD, Cavalleri GL, Gilbert E, Werge T, Hansen TF, Kockum I, Alfredsson L, Olsson T, Hovig E, Gilbert MTP, Stefánsson K, Stenøien HK, Helgason A, Martin MD (2024)
    Corroborating written history with ancient DNA: The case of the Well-man described in an Old Norse saga
    iScience, 27 (11), 111076
    DOI 10.1016/j.isci.2024.111076, PubMed 39620136
15. Emaldi M, Alamillo-Maeso P, Rey-Iborra E, Mosteiro L, Lecumberri D, Pulido R, López JI, Nunes-Xavier CE (2024)
    A functional role for glycosylated B7-H5/VISTA immune checkpoint protein in metastatic clear cell renal cell carcinoma
    iScience, 27 (9), 110587
    DOI 10.1016/j.isci.2024.110587, PubMed 39262813
16. Emaldi M, Rey-Iborra E, Marín Á, Mosteiro L, Lecumberri D, Øyjord T, Roncier N, Mælandsmo GM, Angulo JC, Errarte P, Larrinaga G, Pulido R, López JI, Nunes-Xavier CE (2024)
    Impact of B7-H3 expression on metastasis, immune exhaustion and JAK/STAT and PI3K/AKT pathways in clear cell renal cell carcinoma
    Oncoimmunology, 13 (1), 2419686
    DOI 10.1080/2162402X.2024.2419686, PubMed 39621555
17. Esperon P, Neffa F, Pavicic W, Spirandelli F, Alvarez K, Mullins MJ, Rossi BM, Góngora E Silva RF, Vaccaro C, Lopéz-Köstner F, Rugeles J, Valle AD, Dominguez-Valentin M (2024)
    A comprehensive characterization of the spectrum of MUTYH germline pathogenic variants in Latin America
    Fam Cancer, 23 (4), 507-513
    DOI 10.1007/s10689-024-00382-3, PubMed 38687439
18. Fleischer T, Haugen MH, Ankill J, Silwal-Pandit L, Børresen-Dale AL, Hedenfalk I, Hatschek T, Tost J, Engebraaten O, Kristensen VN (2024)
    An integrated omics approach highlights how epigenetic events can explain and predict response to neoadjuvant chemotherapy and bevacizumab in breast cancer
    Mol Oncol, 18 (8), 2042-2059
    DOI 10.1002/1878-0261.13656, PubMed 38671580
19. Foote JB, Mattox TE, Keeton AB, Chen X, Smith F, Berry KL, Holmes T, Wang J, Huang CH, Ward AB, Mitra AK, Ramirez-Alcantara V, Hardy C, Fleten KG, Flatmark K, Yoon KJ, Sarvesh S, Nagaraju GP, Bandi DSR, Maxuitenko YY, Valiyaveettil J, Carstens JL, Buchsbaum DJ, Yang J, Zhou G et al. (2024)
    A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer
    bioRxiv
    DOI 10.1101/2023.05.17.541233, PubMed 38328254
20. Foote JB, Mattox TE, Keeton AB, Chen X, Smith FT, Berry K, Holmes TW, Wang J, Huang CH, Ward A, Mitra AK, Ramirez-Alcantara V, Hardy C, Fleten KG, Flatmark K, Yoon KJ, Sarvesh S, Nagaraju GP, Bandi DSR, Maxuitenko YY, Valiyaveettil J, Carstens JL, Buchsbaum DJ, Yang J, Zhou G et al. (2024)
    A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer
    Cancer Res (in press)
    DOI 10.1158/0008-5472.CAN-24-0323, PubMed 39700396
21. Guldvik IJ, Ramberg H, Kristensen G, Røder A, Mills IG, Lilleby W, Taskén KA (2024)
    Systemic interrogation of immune-oncology-related proteins in patients with locally advanced prostate cancer undergoing androgen deprivation and intensity-modulated radiotherapy
    World J Urol, 42 (1), 95
    DOI 10.1007/s00345-024-04787-8, PubMed 38386171
22. Heinrich MC, Jones RL, George S, Gelderblom H, Schöffski P, von Mehren M, Zalcberg JR, Kang YK, Razak AA, Trent J, Attia S, Le Cesne A, Siontis BL, Goldstein D, Boye K, Sanchez C, Steeghs N, Rutkowski P, Druta M, Serrano C, Somaiah N, Chi P, Reichmann W, Sprott K, Achour H et al. (2024)
    Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial
    Nat Med, 30 (2), 498-506
    DOI 10.1038/s41591-023-02734-5, PubMed 38182785
23. Istvan P, Birkeland E, Avershina E, Kværner AS, Bemanian V, Pardini B, Tarallo S, de Vos WM, Rognes T, Berstad P, Rounge TB (2024)
    Exploring the gut DNA virome in fecal immunochemical test stool samples reveals associations with lifestyle in a large population-based study
    Nat Commun, 15 (1), 1791
    DOI 10.1038/s41467-024-46033-0, PubMed 38424056
24. Ivarsdottir EV, Gudmundsson J, Tragante V, Sveinbjornsson G, Kristmundsdottir S, Stacey SN, Halldorsson GH, Magnusson MI, Oddsson A, Walters GB, Sigurdsson A, Saevarsdottir S, Beyter D, Thorleifsson G, Halldorsson BV, Melsted P, Stefansson H, Jonsdottir I, Sørensen E, Pedersen OB, Erikstrup C, Bøgsted M, Pøhl M, Røder A, Stroomberg HV et al. (2024)
    Gene-based burden tests of rare germline variants identify six cancer susceptibility genes
    Nat Genet, 56 (11), 2422-2433
    DOI 10.1038/s41588-024-01966-6, PubMed 39472694
25. Kandathil SA, Akhondi A, Kadletz-Wanke L, Heiduschka G, Engedal N, Brkic FF (2024)
    The dual role of autophagy in HPV-positive head and neck squamous cell carcinoma: a systematic review
    J Cancer Res Clin Oncol, 150 (2), 56
    DOI 10.1007/s00432-023-05514-3, PubMed 38291202
26. Katona BW, Lubinski J, Pal T, Huzarski T, Foulkes WD, Moller P, Eisen A, Randall Armel S, Neuhausen SL, Raj R, Aeilts A, Singer CF, Bordeleau L, Karlan B, Olopade O, Tung N, Zakalik D, Kotsopoulos J, Fruscio R, Eng C, Sun P, Narod SA, Hereditary Breast Cancer Clinical Study Group (2024)
    The incidence of pancreatic cancer in women with a BRCA1 or BRCA2 mutation
    Cancer (in press)
    DOI 10.1002/cncr.35666, PubMed 39611336
27. Kiviaho A, Eerola SK, Kallio HML, Andersen MK, Hoikka M, Tiihonen AM, Salonen I, Spotbeen X, Giesen A, Parker CTA, Taavitsainen S, Hantula O, Marttinen M, Hermelo I, Ismail M, Midtbust E, Wess M, Devlies W, Sharma A, Krossa S, Häkkinen T, Afyounian E, Vandereyken K, Kint S, Kesseli J et al. (2024)
    Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer
    Nat Commun, 15 (1), 9949
    DOI 10.1038/s41467-024-54364-1, PubMed 39550375
28. Kotsopoulos J, Gronwald J, Huzarski T, Møller P, Pal T, McCuaig JM, Singer CF, Karlan BY, Aeilts A, Eng C, Eisen A, Bordeleau L, Foulkes WD, Tung N, Couch FJ, Fruscio R, Neuhausen SL, Zakalik D, Cybulski C, Metcalfe K, Olopade OI, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2024)
    Bilateral Oophorectomy and All-Cause Mortality in Women With BRCA1 and BRCA2 Sequence Variations
    JAMA Oncol, 10 (4), 484-492
    DOI 10.1001/jamaoncol.2023.6937, PubMed 38421677
29. Kotsopoulos J, Lubinski J, Huzarski T, Bychkovsky BL, Moller P, Kim RH, Tung N, Eisen A, Foulkes W, Singer CF, Aeilts A, Neuhausen SL, Bordeleau L, Karlan B, Fruscio R, Eng C, Olopade O, Zakalik D, Couch F, Y Cajal TR, Sun P, Gronwald J, Narod SA (2024)
    Incidence of endometrial cancer in BRCA mutation carriers
    Gynecol Oncol, 189, 148-155
    DOI 10.1016/j.ygyno.2024.07.687, PubMed 39173195
30. Kurganovs NJ, Engedal N (2024)
    To eat or not to eat: a critical review on the role of autophagy in prostate carcinogenesis and prostate cancer therapeutics
    Front Pharmacol, 15, 1419806
    DOI 10.3389/fphar.2024.1419806, PubMed 38910881
31. Lamsal A, Andersen SB, Johansson I, Desgarnier MD, Wolowczyk C, Engedal N, Vietri M, Bjørkøy G, Giambelluca MS, Pettersen K (2024)
    Elucidating the power of arginine restriction: taming type I interferon response in breast cancer via selective autophagy
    Cell Commun Signal, 22 (1), 481
    DOI 10.1186/s12964-024-01858-6, PubMed 39380098
32. Lubinski J, Kotsopoulos J, Moller P, Pal T, Eisen A, Peck L, Karlan BY, Aeilts A, Eng C, Bordeleau L, Foulkes WD, Tung N, Couch FJ, Fruscio R, Ramon Y Cajal T, Singer CF, Neuhausen SL, Zakalik D, Cybulski C, Gronwald J, Huzarski T, Stempa K, Dungan J, Cullinane C, Olopade OI et al. (2024)
    MRI Surveillance and Breast Cancer Mortality in Women With BRCA1 and BRCA2 Sequence Variations
    JAMA Oncol, 10 (4), 493-499
    DOI 10.1001/jamaoncol.2023.6944, PubMed 38421676
33. Lund-Andersen C, Torgunrud A, Kanduri C, Dagenborg VJ, Frøysnes IS, Larsen MM, Davidson B, Larsen SG, Flatmark K (2024)
    Novel drug resistance mechanisms and drug targets in BRAF-mutated peritoneal metastasis from colorectal cancer
    J Transl Med, 22 (1), 646
    DOI 10.1186/s12967-024-05467-2, PubMed 38982444
34. Mattavelli D, Wichmann G, Smussi D, Paderno A, Plana MS, Mesia RN, Compagnoni M, Medda A, Chiocca S, Calza S, Zhan Y, Rognoni C, Tarricone R, Stucchi E, Lorini L, Gurizzan C, Khelik K, Hovig E, Dietz A, Piazza C, Bossi P (2024)
    Is precision medicine the solution to improve organ preservation in laryngeal/hypopharyngeal cancer? A position paper by the Preserve Research Group
    Front Oncol, 14, 1433333
    DOI 10.3389/fonc.2024.1433333, PubMed 39165689
35. Møller P, Haupt S, Ahadova A, Kloor M, Sampson JR, Sunde L, Seppälä T, Burn J, Bernstein I, Capella G, Evans DG, Lindblom A, Winship I, Macrae F, Katz L, Laish I, Vainer E, Monahan K, Half E, Horisberger K, da Silva LA, Heuveline V, Therkildsen C, Lautrup C, Klarskov LL et al. (2024)
    Incidences of colorectal adenomas and cancers under colonoscopy surveillance suggest an accelerated "Big Bang" pathway to CRC in three of the four Lynch syndromes
    Hered Cancer Clin Pract, 22 (1), 6
    DOI 10.1186/s13053-024-00279-3, PubMed 38741120
36. Møller P, Hovig E (2024)
    Genetic testing for prevention and treatment of cancer
    Tidsskr Nor Laegeforen, 144 (13)
    DOI 10.4045/tidsskr.24.0434, PubMed 39498653
37. Møller P, Seppälä TT, Dominguez-Valentin M, Sampson J (2024)
    Commentary on Estimating cancer risk in carriers of Lynch syndrome variants in UK Biobank
    J Med Genet (in press)
    DOI 10.1136/jmg-2024-110385, PubMed 39375027
38. Narod SA, Gronwald J, Karlan B, Moller P, Huzarski T, Tung N, Aeilts A, Eisen A, Armel SR, Singer CF, Foulkes WD, Neuhausen SL, Olopade O, Pal T, Fruscio R, Metcalfe K, Raj R, Jacobson M, Sun P, Lubinski J, Kotsopoulos J (2024)
    Incidence of peritoneal cancer after oophorectomy among BRCA1 and BRCA2 mutation carriers
    J Natl Cancer Inst, 116 (11), 1753-1760
    DOI 10.1093/jnci/djae151, PubMed 38937272
39. Niehusmann P, Leske H, Nygaard V, Russnes HG, Zhao S, Latysheva A, Straume Wiig U, Stankuniene B, Ulvmoen A (2024)
    Desmoplastic non-infantile ganglioglioma mimicking diffuse leptomeningeal glioneuronal tumor: precision diagnostics and therapeutic implications
    Acta Oncol, 63, 392-394
    DOI 10.2340/1651-226X.2024.31720, PubMed 38779936
40. Nikolski M, Hovig E, Al-Shahrour F, Blomberg N, Scollen S, Valencia A, Saunders G (2024)
    Roadmap for a European cancer data management and precision medicine infrastructure
    Nat Cancer, 5 (3), 367-372
    DOI 10.1038/s43018-023-00717-6, PubMed 38321342
41. Nunes-Xavier CE (2024)
    Editorial: Co-inhibitory immune checkpoint proteins as biomarkers and therapeutic targets in cancer
    Transl Oncol, 47, 102005
    DOI 10.1016/j.tranon.2024.102005, PubMed 39034056
42. Patrick-Brown TDJH, Barratt-Due A, Trøseid M, Dyrhol-Riise AM, Nezvalova-Henriksen K, Kåsine T, Aukrust P, Olsen IC, NOR Solidarity consortium (2024)
    The effects of remdesivir on long-term symptoms in patients hospitalised for COVID-19: a pre-specified exploratory analysis
    Commun Med (Lond), 4 (1), 231
    DOI 10.1038/s43856-024-00650-4, PubMed 39533001
43. Patrick-Brown TDJH, Bourner J, Kali S, Trøseid M, Yazdanpanah Y, Olliaro P, Olsen IC (2024)
    Experiences and challenges with the new European Clinical Trials Regulation
    Trials, 25 (1), 3
    DOI 10.1186/s13063-023-07869-x, PubMed 38167484
44. Pulido R, López JI, Nunes-Xavier CE (2024)
    B7-H3: a robust target for immunotherapy in prostate cancer
    Trends Cancer, 10 (7), 584-587
    DOI 10.1016/j.trecan.2024.05.003, PubMed 38839545
45. Ranji P, Jonasson E, Andersson L, Filges S, Luna Santamaría M, Vannas C, Dolatabadi S, Gustafsson A, Myklebost O, Håkansson J, Fagman H, Landberg G, Åman P, Ståhlberg A (2024)
    Deciphering the role of FUS::DDIT3 expression and tumor microenvironment in myxoid liposarcoma development
    J Transl Med, 22 (1), 389
    DOI 10.1186/s12967-024-05211-w, PubMed 38671504
46. Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Chèneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A (2024)
    JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
    Nucleic Acids Res, 52 (D1), D174-D182
    DOI 10.1093/nar/gkad1059, PubMed 37962376
47. Ree AH, Høye E, Esbensen Y, Beitnes AR, Negård A, Bernklev L, Tetlie LK, Fretland ÅA, Hamre HM, Kersten C, Hofsli E, Guren MG, Sorbye H, Nilsen HL, Flatmark K, Meltzer S (2024)
    Complete response of metastatic microsatellite-stable BRAF V600E colorectal cancer to first-line oxaliplatin-based chemotherapy and immune checkpoint blockade
    Oncoimmunology, 13 (1), 2372886
    DOI 10.1080/2162402X.2024.2372886, PubMed 38952672
48. Ree AH, Šaltytė Benth J, Hamre HM, Kersten C, Hofsli E, Guren MG, Sorbye H, Johansen C, Negård A, Bjørnetrø T, Nilsen HL, Berg JP, Flatmark K, Meltzer S (2024)
    First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer-the randomised METIMMOX trial
    Br J Cancer, 130 (12), 1921-1928
    DOI 10.1038/s41416-024-02696-6, PubMed 38664577
49. Reppe S, Gundersen S, Sandve GK, Wang Y, Andreassen OA, Medina-Gomez C, Rivadeneira F, Utheim TP, Hovig E, Gautvik KM (2024)
    Identification of Transcripts with Shared Roles in the Pathogenesis of Postmenopausal Osteoporosis and Cardiovascular Disease
    Int J Mol Sci, 25 (10)
    DOI 10.3390/ijms25105554, PubMed 38791593
50. Schiffer PH, Natsidis P, Leite DJ, Robertson HE, Lapraz F, Marlétaz F, Fromm B, Baudry L, Simpson F, Høye E, Zakrzewski AC, Kapli P, Hoff KJ, Müller S, Marbouty M, Marlow H, Copley RR, Koszul R, Sarkies P, Telford MJ (2024)
    Insights into early animal evolution from the genome of the xenacoelomorph worm Xenoturbella bocki
    Elife, 13
    DOI 10.7554/eLife.94948, PubMed 39109482
51. Soarez J, Vaccaro CA, Dominguez-Valentin M, Pavicic WH (2024)
    Editorial: Advances in genetics and molecular diagnosis in colorectal, stomach, and pancreatic cancer vol II
    Front Oncol, 14, 1448183
    DOI 10.3389/fonc.2024.1448183, PubMed 39050580
52. Sveen A, Johannessen B, Klokkerud SM, Kraggerud SM, Meza-Zepeda LA, Bjørnslett M, Bischof K, Myklebost O, Taskén K, Skotheim RI, Dørum A, Davidson B, Lothe RA (2024)
    Evolutionary mode and timing of dissemination of high-grade serous carcinomas
    JCI Insight, 9 (3)
    DOI 10.1172/jci.insight.170423, PubMed 38175731
53. Torices L, Nunes-Xavier CE, Mingo J, Luna S, Erramuzpe A, Cortés JM, Pulido R (2024)
    Induction of Translational Readthrough on Protein Tyrosine Phosphatases Targeted by Premature Termination Codon Mutations in Human Disease
    Methods Mol Biol, 2743, 1-19
    DOI 10.1007/978-1-0716-3569-8_1, PubMed 38147205
54. Torices L, Nunes-Xavier CE, Pulido R (2024)
    Potentiation by Protein Synthesis Inducers of Translational Readthrough of Pathogenic Premature Termination Codons in PTEN Isoforms
    Cancers (Basel), 16 (16)
    DOI 10.3390/cancers16162836, PubMed 39199607
55. Valsalakumari R, Pandya AD, Prasmickaite L, Kvalvaag A, Myrann AG, Åslund AKO, Kjos MS, Fontecha-Cuenca C, Haroon HB, Ribeiro ARS, Horejs-Hoeck J, Moghimi SM, Mørch Ý, Skotland T, Sandvig K, Mælandsmo GM, Iversen TG (2024)
    Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants
    Int J Nanomedicine, 19, 3009-3029
    DOI 10.2147/IJN.S450283, PubMed 38562610
56. van der Werf-'t Lam AS, Rodriguez-Girondo M, Villasmil M, Tops CM, van Hest L, Gille HJP, Duijkers FAM, Wagner A, Eikenboom E, Letteboer TGW, de Jong MM, Bajwa-Ten Broeke SW, Bleeker F, Gomez Garcia EB, Dominguez-Valentin M, Møller P, Suerink M, Nielsen M (2024)
    Delineating genotype and parent-of-origin effect on the phenotype in MSH6-associated Lynch syndrome
    Genes Chromosomes Cancer, 63 (5), e23237
    DOI 10.1002/gcc.23237, PubMed 38722212
57. Wiig JN, Dagenborg VJ, Larsen SG (2024)
    Ten-year survival and pattern of recurrence in patients with locally recurrent rectal or sigmoid cancer undergoing resection
    Colorectal Dis (in press)
    DOI 10.1111/codi.17226, PubMed 39635974
58. Zhou Y, Ray PS, Zhu J, Stein F, Rettel M, Sekaran T, Sahadevan S, Perez-Perri JI, Roth EK, Myklebost O, Meza-Zepeda LA, von Deimling A, Fu C, Brosig AN, Boye K, Nathrath M, Blattmann C, Lehner B, Hentze MW, Kulozik AE (2024)
    Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma
    Nat Commun, 15 (1), 2810
    DOI 10.1038/s41467-024-47031-y, PubMed 38561347

Publications 2023

1. Akdeniz BC, Mattingsdal M, Dominguez-Valentin M, Frei O, Shadrin A, Puustusmaa M, Saar R, Sõber S, Møller P, Andreassen OA, Padrik P, Hovig E (2023)
   A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population
   Cancers (Basel), 15 (16)
   DOI 10.3390/cancers15164124, PubMed 37627152
2. Anzar I, Malone B, Samarakoon P, Vardaxis I, Simovski B, Fontenelle H, Meza-Zepeda LA, Stratford R, Keung EZ, Burgess M, Tawbi HA, Myklebost O, Clancy T (2023)
   The interplay between neoantigens and immune cells in sarcomas treated with checkpoint inhibition
   Front Immunol, 14, 1226445
   DOI 10.3389/fimmu.2023.1226445, PubMed 37799721
3. Arjona-Sanchez A, Martinez-López A, Moreno-Montilla MT, Mulsow J, Lozano-Lominchar P, Martínez-Torres B, Rau B, Canbay E, Sommariva A, Milione M, Deraco M, Sgarbura O, Torgunrud A, Kepenekian V, Carr NJ, Hoorens A, Delhorme JB, Wernert R, Goere D, Martin-Roman L, Cosyns S, Flatmark K, Davidson B, Khellaf L, Pereira-Perez F et al. (2023)
   External multicentre validation of pseudomyxoma peritonei PSOGI-Ki67 classification
   Eur J Surg Oncol, 49 (8), 1481-1488
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4. Ballinger ML, Pattnaik S, Mundra PA, Zaheed M, Rath E, Priestley P, Baber J, Ray-Coquard I, Isambert N, Causeret S, van der Graaf WTA, Puri A, Duffaud F, Le Cesne A, Seddon B, Chandrasekar C, Schiffman JD, Brohl AS, James PA, Kurtz JE, Penel N, Myklebost O, Meza-Zepeda LA, Pickett H, Kansara M et al. (2023)
   Heritable defects in telomere and mitotic function selectively predispose to sarcomas
   Science, 379 (6629), 253-260
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5. Billingham L, Brown L, Framke T, Greystoke A, Hovig E, Mathur S, Page P, Pean E, Barjesteh van Waalwijk van Doorn-Khosrovani S, Vonk R, Wissink S, Zander H, Plummer R (2023)
   Histology independent drug development - Is this the future for cancer drugs?
   Cancer Treat Rev, 123, 102674
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6. Bucher-Johannessen C, Birkeland EE, Vinberg E, Bemanian V, Hoff G, Berstad P, Rounge TB (2023)
   Long-term follow-up of colorectal cancer screening attendees identifies differences in Phascolarctobacterium spp. using 16S rRNA and metagenome sequencing
   Front Oncol, 13, 1183039
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7. Dominguez-Valentin M, Haupt S, Seppälä TT, Sampson JR, Sunde L, Bernstein I, Jenkins MA, Engel C, Aretz S, Nielsen M, Capella G, Balaguer F, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Della Valle A et al. (2023)
   Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database
   EClinicalMedicine, 58, 101909
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8. Doutel D, Davidson B, Nitschke Pettersen IK, Torgunrud A (2023)
   Molecular characteristics of low-grade serous carcinoma in effusions
   Cytopathology, 34 (2), 99-105
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9. Ellingsen EB, O'Day S, Mezheyeuski A, Gromadka A, Clancy T, Kristedja TS, Milhem M, Zakharia Y (2023)
   Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial
   Clin Cancer Res, 29 (16), 3026-3036
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10. Figlioli G, Billaud A, Wang Q, Bolla MK, Dennis J, Lush M, Kvist A, Adank MA, Ahearn TU, Antonenkova NN, Auvinen P, Behrens S, Bermisheva M, Bogdanova NV, Bojesen SE, Bonanni B, Brüning T, Camp NJ, Campbell A, Castelao JE, Cessna MH, Nbcs Collaborators, Czene K, Devilee P, Dörk T et al. (2023)
    Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases
    Cancers (Basel), 15 (13)
    DOI 10.3390/cancers15133313, PubMed 37444426
11. Getu AA, Tigabu A, Zhou M, Lu J, Fodstad Ø, Tan M (2023)
    New frontiers in immune checkpoint B7-H3 (CD276) research and drug development
    Mol Cancer, 22 (1), 43
    DOI 10.1186/s12943-023-01751-9, PubMed 36859240
12. Ghannoum S, Fantini D, Zahoor M, Reiterer V, Phuyal S, Leoncio Netto W, Sørensen Ø, Iyer A, Sengupta D, Prasmickaite L, Mælandsmo GM, Köhn-Luque A, Farhan H (2023)
    A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression
    PLoS Comput Biol, 19 (4), e1010995
    DOI 10.1371/journal.pcbi.1010995, PubMed 37068117
13. Hanes R, Ayuda-Durán P, Rønneberg L, Nakken S, Hovig E, Zucknick M, Enserink JM (2023)
    screenwerk: a modular tool for the design and analysis of drug combination screens
    Bioinformatics, 39 (1)
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14. Haugen MH, von der Lippe Gythfeldt H, Egeland EV, Svartdal Normann L, Pandya AD, Vedin LL, Juell S, Tenstad E, Øy GF, Kristian A, Marangoni E, Sørlie T, Steffensen K, Maelandsmo GM, Engebraaten O (2023)
    Liver X receptors induce antiproliferative effects in basal-like breast cancer
    Mol Oncol, 17 (10), 2041-2055
    DOI 10.1002/1878-0261.13476, PubMed 37341140
15. Hodan R, Rodgers-Fouche L, Chittenden A, Dominguez-Valentin M, Ferriss J, Gima L, Hamnvik OR, Idos GE, Kline K, Koeller DR, Long JM, McKenna D, Muller C, Thoman M, Wintner A, Bedrick BS, Collaborative Group of the Americas on Inherited Gastrointestinal Cancer (2023)
    Cancer surveillance for transgender and gender diverse patients with Lynch syndrome: a practice resource of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
    Fam Cancer, 22 (4), 437-448
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16. Holme B, Bjørnerud B, Pedersen NM, de la Ballina LR, Wesche J, Haugsten EM (2023)
    Automated tracking of cell migration in phase contrast images with CellTraxx
    Sci Rep, 13 (1), 22982
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17. Hyldbakk A, Fleten KG, Snipstad S, Åslund AKO, Davies CL, Flatmark K, Mørch Y (2023)
    Intraperitoneal administration of cabazitaxel-loaded nanoparticles in peritoneal metastasis models
    Nanomedicine, 48, 102656
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18. Ibrahim EIK, Ellingsen EB, Mangsbo SM, Friberg LE (2023)
    Bridging responses to a human telomerase reverse transcriptase-based peptide cancer vaccine candidate in a mechanism-based model
    Int Immunopharmacol, 126, 111225
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19. Ito I, Yousef AM, Dickson PN, Naini ZA, White MG, Fleten KG, Flatmark K, Fournier KF, Fowlkes NW, Shen JP (2023)
    Antitumor activity of intraperitoneal paclitaxel in orthotopic patient-derived xenograft models of mucinous appendiceal adenocarcinoma
    bioRxiv
    DOI 10.1101/2023.02.01.526672, PubMed 36993681
20. Kalyanasundaram S, Lefol Y, Gundersen S, Rognes T, Alsøe L, Nilsen HL, Hovig E, Sandve GK, Domanska D (2023)
    hGSuite HyperBrowser: A web-based toolkit for hierarchical metadata-informed analysis of genomic tracks
    PLoS One, 18 (7), e0286330
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21. Knutsen E, Das Sajib S, Fiskaa T, Lorens J, Gudjonsson T, Mælandsmo GM, Johansen SD, Seternes OM, Perander M (2023)
    Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypes
    Front Oncol, 13, 1249895
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22. Lamsal A, Andersen SB, Johansson I, Vietri M, Bokil AA, Kurganovs NJ, Rylander F, Bjørkøy G, Pettersen K, Giambelluca MS (2023)
    Opposite and dynamic regulation of the interferon response in metastatic and non-metastatic breast cancer
    Cell Commun Signal, 21 (1), 50
    DOI 10.1186/s12964-023-01062-y, PubMed 36882786
23. López JI, Hogan MF, Sutton B, Church SE, Angulo JC, Nunes-Xavier CE (2023)
    Distinct spatial landscapes in clear-cell renal cell carcinoma as revealed by whole transcriptome analysis
    Immunooncol Technol, 21, 100690
    DOI 10.1016/j.iotech.2023.100690, PubMed 38292905
24. Mo T, Brandal SHB, Geier OM, Engebråten O, Nilsen LB, Kristensen VN, Hole KH, Hompland T, Fleischer T, Seierstad T (2023)
    MRI Assessment of Changes in Tumor Vascularization during Neoadjuvant Anti-Angiogenic Treatment in Locally Advanced Breast Cancer Patients
    Cancers (Basel), 15 (18)
    DOI 10.3390/cancers15184662, PubMed 37760629
25. Mraz KA, Hodan R, Rodgers-Fouche L, Arora S, Balaguer F, Guillem JG, Jeter JM, Kanth P, Li D, Liska D, Melson J, Perez K, Ricker C, Shirts BH, Vilar E, Katona BW, Dominguez-Valentin M (2023)
    Current chemoprevention approaches in Lynch syndrome and Familial adenomatous polyposis: a global clinical practice survey
    Front Oncol, 13, 1141810
    DOI 10.3389/fonc.2023.1141810, PubMed 37293588
26. Møller P, Seppälä TT, Ahadova A, Crosbie EJ, Holinski-Feder E, Scott R, Haupt S, Möslein G, Winship I, Broeke SWB, Kohut KE, Ryan N, Bauerfeind P, Thomas LE, Evans DG, Aretz S, Sijmons RH, Half E, Heinimann K, Horisberger K, Monahan K, Engel C, Cavestro GM, Fruscio R, Abu-Freha N et al. (2023)
    Dominantly inherited micro-satellite instable cancer - the four Lynch syndromes - an EHTG, PLSD position statement
    Hered Cancer Clin Pract, 21 (1), 19
    DOI 10.1186/s13053-023-00263-3, PubMed 37821984
27. Nakken S, Gundersen S, Bernal FLM, Polychronopoulos D, Hovig E, Wesche J (2023)
    Comprehensive interrogation of gene lists from genome-scale cancer screens with oncoEnrichR
    Int J Cancer, 153 (10), 1819-1828
    DOI 10.1002/ijc.34666, PubMed 37551617
28. Namløs HM, Khelik K, Nakken S, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2023)
    Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential
    Mol Oncol, 17 (11), 2432-2450
    DOI 10.1002/1878-0261.13514, PubMed 37622176
29. Normann LS, Haugen MH, Hongisto V, Aure MR, Leivonen SK, Kristensen VN, Tahiri A, Engebraaten O, Sahlberg KK, Mælandsmo GM (2023)
    High-throughput screen in vitro identifies dasatinib as a candidate for combinatorial treatment with HER2-targeting drugs in breast cancer
    PLoS One, 18 (1), e0280507
    DOI 10.1371/journal.pone.0280507, PubMed 36706086
30. Nunes-Xavier CE, Emaldi M, Mingo J, Øyjord T, Mælandsmo GM, Fodstad Ø, Errarte P, Larrinaga G, Llarena R, López JI, Pulido R (2023)
    The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma
    Sci Rep, 13 (1), 7339
    DOI 10.1038/s41598-023-34087-x, PubMed 37147361
31. Nunes-Xavier CE, Emaldi M, Mingo J, Øyjord T, Mælandsmo GM, Fodstad Ø, Errarte P, Larrinaga G, Llarena R, López JI, Pulido R (2023)
    Author Correction: The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma
    Sci Rep, 13 (1), 9186
    DOI 10.1038/s41598-023-36328-5, PubMed 37280349
32. Nygaard V, Ree AH, Dagenborg VJ, Børresen-Dale AL, Edwin B, Fretland ÅA, Grzyb K, Haugen MH, Mælandsmo GM, Flatmark K (2023)
    A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases
    Cancer Res Commun, 3 (2), 235-244
    DOI 10.1158/2767-9764.CRC-22-0295, PubMed 36968142
33. Parry MA, Grist E, Mendes L, Dutey-Magni P, Sachdeva A, Brawley C, Murphy L, Proudfoot J, Lall S, Liu Y, Friedrich S, Ismail M, Hoyle A, Ali A, Haran A, Wingate A, Zakka L, Wetterskog D, Amos CL, Atako NB, Wang V, Rush HL, Jones RJ, Leung H, Cross WR et al. (2023)
    Clinical testing of transcriptome-wide expression profiles in high-risk localized and metastatic prostate cancer starting androgen deprivation therapy: an ancillary study of the STAMPEDE abiraterone Phase 3 trial
    Res Sq
    DOI 10.21203/rs.3.rs-2488586/v1, PubMed 36798177
34. Patrick-Brown TDJH, Mohamed F, Thrower A, Torgunrud A, Cosyns S, Canbay E, Villeneuve L, Flatmark K, Brandl A (2023)
    Determining a minimum data set for reporting clinical and radiologic data for pseudomyxoma peritonei
    Pleura Peritoneum, 8 (1), 1-9
    DOI 10.1515/pp-2022-0200, PubMed 37020469
35. Pettersen S, Øy GF, Egeland EV, Juell S, Engebråten O, Mælandsmo GM, Prasmickaite L (2023)
    Breast cancer patient-derived explant cultures recapitulate in vivo drug responses
    Front Oncol, 13, 1040665
    DOI 10.3389/fonc.2023.1040665, PubMed 36910663
36. Połeć A, Ekstrøm PO, Fougner C, Sørlie T, Norum JH (2023)
    Rapid assessment of 3-dimensional intra-tumor heterogeneity through cycling temperature capillary electrophoresis
    BMC Res Notes, 16 (1), 167
    DOI 10.1186/s13104-023-06437-5, PubMed 37568187
37. Pulido R, Nunes-Xavier CE (2023)
    Editorial: Cell and Developmental Signalling in Neuroblastoma
    Front Cell Dev Biol, 10, 1126352
    DOI 10.3389/fcell.2022.1126352, PubMed 36684434
38. Rodgers-Fouche L, Arora S, Ricker C, Li D, Farooqi M, Balaguer F, Dominguez-Valentin M, Guillem JG, Kanth P, Liska D, Melson J, Mraz KA, Shirts BH, Vilar E, Katona BW, Hodan R (2023)
    Exploring Stakeholders' Perspectives on Implementing Universal Germline Testing for Colorectal Cancer: Findings From a Clinical Practice Survey
    JCO Precis Oncol, 7, e2300440
    DOI 10.1200/PO.23.00440, PubMed 37897815
39. Rodríguez-Varela R, Moore KHS, Ebenesersdóttir SS, Kilinc GM, Kjellström A, Papmehl-Dufay L, Alfsdotter C, Berglund B, Alrawi L, Kashuba N, Sobrado V, Lagerholm VK, Gilbert E, Cavalleri GL, Hovig E, Kockum I, Olsson T, Alfredsson L, Hansen TF, Werge T, Munters AR, Bernhardsson C, Skar B, Christophersen A, Turner-Walker G et al. (2023)
    The genetic history of Scandinavia from the Roman Iron Age to the present
    Cell, 186 (1), 32-46.e19
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    Enhancer profiling identifies epigenetic markers of endocrine resistance and reveals therapeutic options for metastatic castration-resistant prostate cancer patients
    medRxiv
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    ASO Author Reflections: Navigation-Assisted Surgery for Locally Advanced and Recurrent Rectal Cancer: The NAVI-LARRC Trial
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    Navigation-Assisted Surgery for Locally Advanced Primary and Recurrent Rectal Cancer
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    Analysis of ATG4C function in vivo
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    Short-term results after robot-assisted surgery for primary rectal cancers requiring beyond total mesorectal excision in multiple compartments
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Publications 2022

1. Ahadova A, Witt J, Haupt S, Gallon R, Hüneburg R, Nattermann J, Ten Broeke S, Bohaumilitzky L, Hernandez-Sanchez A, Santibanez-Koref M, Jackson MS, Ahtiainen M, Pylvänäinen K, Andini K, Grolmusz VK, Möslein G, Dominguez-Valentin M, Møller P, Fürst D, Sijmons R, Borthwick GM, Burn J, Mecklin JP, Heuveline V, von Knebel Doeberitz M et al. (2022)
   Is HLA type a possible cancer risk modifier in Lynch syndrome?
   Int J Cancer, 152 (10), 2024-2031
   DOI 10.1002/ijc.34312, PubMed 36214792
2. Alaña L, Nunes-Xavier CE, Zaldumbide L, Martin-Guerrero I, Mosteiro L, Alba-Pavón P, Villate O, García-Obregón S, González-García H, Herraiz R, Astigarraga I, Pulido R, García-Ariza M (2022)
   Identification and Functional Analysis of a Novel CTNNB1 Mutation in Pediatric Medulloblastoma
   Cancers (Basel), 14 (2)
   DOI 10.3390/cancers14020421, PubMed 35053583
3. Alver TN, Heintz KM, Hovig E, Bøe SL (2022)
   Cooperative induction of receptor tyrosine kinases contributes to adaptive MAPK drug resistance in melanoma through the PI3K pathway
   Cancer Rep (Hoboken), 6 (2), e1736
   DOI 10.1002/cnr2.1736, PubMed 36251678
4. Ambrosini M, Del Re M, Manca P, Hendifar A, Drilon A, Harada G, Ree AH, Klempner S, Mælandsmo GM, Flatmark K, Russnes HG, Cleary JM, Singh H, Sottotetti E, Martinetti A, Randon G, Sartore-Bianchi A, Capone I, Milione M, Di Bartolomeo M, Pietrantonio F (2022)
   ALK Inhibitors in Patients With ALK Fusion-Positive GI Cancers: An International Data Set and a Molecular Case Series
   JCO Precis Oncol, 6 (1), e2200015
   DOI 10.1200/PO.22.00015, PubMed 35476549
5. Bjørklund SS, Aure MR, Häkkinen J, Vallon-Christersson J, Kumar S, Evensen KB, Fleischer T, Tost J, OSBREAC, Sahlberg KK, Mathelier A, Bhanot G, Ganesan S, Tekpli X, Kristensen VN (2022)
   Subtype and cell type specific expression of lncRNAs provide insight into breast cancer
   Commun Biol, 5 (1), 834
   DOI 10.1038/s42003-022-03559-7, PubMed 35982125
6. Cao S, Wang JR, Ji S, Yang P, Dai Y, Guo S, Montierth MD, Shen JP, Zhao X, Chen J, Lee JJ, Guerrero PA, Spetsieris N, Engedal N, Taavitsainen S, Yu K, Livingstone J, Bhandari V, Hubert SM, Daw NC, Futreal PA, Efstathiou E, Lim B, Viale A, Zhang J et al. (2022)
   Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression
   Nat Biotechnol, 40 (11), 1624-1633
   DOI 10.1038/s41587-022-01342-x, PubMed 35697807
7. Cavestro GM, Mannucci A, Balaguer F, Hampel H, Kupfer SS, Repici A, Sartore-Bianchi A, Seppälä TT, Valentini V, Boland CR, Brand RE, Buffart TE, Burke CA, Caccialanza R, Cannizzaro R, Cascinu S, Cercek A, Crosbie EJ, Danese S, Dekker E, Daca-Alvarez M, Deni F, Dominguez-Valentin M, Eng C, Goel A et al. (2022)
   Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines
   Clin Gastroenterol Hepatol, 21 (3), 581-603.e33
   DOI 10.1016/j.cgh.2022.12.006, PubMed 36549470
8. Dominguez-Valentin M, Sampson JR, Seppälä TT, Møller P (2022)
   Response to Chambuso et al
   Genet Med, 24 (5), 1151
   DOI 10.1016/j.gim.2022.01.005, PubMed 35216900
9. Ellingsen EB, Bounova G, Kerzeli I, Anzar I, Simnica D, Aamdal E, Guren T, Clancy T, Mezheyeuski A, Inderberg EM, Mangsbo SM, Binder M, Hovig E, Gaudernack G (2022)
   Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination
   J Transl Med, 20 (1), 419
   DOI 10.1186/s12967-022-03624-z, PubMed 36089578
10. Ellingsen EB, Aamdal E, Guren T, Lilleby W, Brunsvig PF, Mangsbo SM, Aamdal S, Hovig E, Mensali N, Gaudernack G, Inderberg EM (2022)
    Durable and dynamic hTERT immune responses following vaccination with the long-peptide cancer vaccine UV1: long-term follow-up of three phase I clinical trials
    J Immunother Cancer, 10 (5)
    DOI 10.1136/jitc-2021-004345, PubMed 35613827
11. Emaldi M, Nunes-Xavier CE (2022)
    B7-H4 Immune Checkpoint Protein Affects Viability and Targeted Therapy of Renal Cancer Cells
    Cells, 11 (9)
    DOI 10.3390/cells11091448, PubMed 35563753
12. Engedal N, Proikas-Cezanne T, Albertini MC, Žerovnik E, Lane JD (2022)
    Transautophagy: Research and Translation of Autophagy Knowledge 2020
    Oxid Med Cell Longev, 2022, 9792132
    DOI 10.1155/2022/9792132, PubMed 35340207
13. Engedal N, Sønstevold T, Beese CJ, Selladurai S, Melcher T, Simensen JE, Frankel LB, Urbanucci A, Torgersen ML (2022)
    Measuring Autophagic Cargo Flux with Keima-Based Probes
    Methods Mol Biol, 2445, 99-115
    DOI 10.1007/978-1-0716-2071-7_7, PubMed 34972988
14. Fiorito E, Szybowska P, Haugsten EM, Kostas M, Øy GF, Wiedlocha A, Singh S, Nakken S, Mælandsmo GM, Fletcher JA, Meza-Zepeda LA, Wesche J (2022)
    Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
    Br J Cancer, 127 (11), 1939-1953
    DOI 10.1038/s41416-022-01973-6, PubMed 36097178
15. Fleten KG, Hyldbakk A, Einen C, Benjakul S, Strand BL, Davies CL, Mørch Ý, Flatmark K (2022)
    Alginate Microsphere Encapsulation of Drug-Loaded Nanoparticles: A Novel Strategy for Intraperitoneal Drug Delivery
    Mar Drugs, 20 (12)
    DOI 10.3390/md20120744, PubMed 36547891
16. Flobak Å, Skånland SS, Hovig E, Taskén K, Russnes HG (2022)
    Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
    Trends Pharmacol Sci, 43 (11), 973-985
    DOI 10.1016/j.tips.2022.08.009, PubMed 36163057
17. Fromm B, Høye E, Domanska D, Zhong X, Aparicio-Puerta E, Ovchinnikov V, Umu SU, Chabot PJ, Kang W, Aslanzadeh M, Tarbier M, Mármol-Sánchez E, Urgese G, Johansen M, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2022)
    MirGeneDB 2.1: toward a complete sampling of all major animal phyla
    Nucleic Acids Res, 50 (D1), D204-D210
    DOI 10.1093/nar/gkab1101, PubMed 34850127
18. Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2022)
    Corrigendum to "Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft", [Journal of Control Release, 293 (2019) 183-192]
    J Control Release, 349, 1
    DOI 10.1016/j.jconrel.2022.06.040, PubMed 35792388
19. Georgiesh T, Aggerholm-Pedersen N, Schöffski P, Zhang Y, Napolitano A, Bovée JVMG, Hjelle Å, Tang G, Spalek M, Nannini M, Swanson D, Baad-Hansen T, Sciot R, Hesla AC, Huang P, Dorleijn D, Haugland HK, Lacambra M, Skoczylas J, Pantaleo MA, Haas RL, Meza-Zepeda LA, Haller F, Czarnecka AM, Loong H et al. (2022)
    Validation of a novel risk score to predict early and late recurrence in solitary fibrous tumour
    Br J Cancer, 127 (10), 1793-1798
    DOI 10.1038/s41416-022-01959-4, PubMed 36030294
20. Giliberto M, Santana LM, Holien T, Misund K, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Coward E, Waage A, Taskén K, Skånland SS (2022)
    Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
    Front Oncol, 12, 1040730
    DOI 10.3389/fonc.2022.1040730, PubMed 36523963
21. Gopalakrishnan S, Ebenesersdóttir SS, Lundstrøm IKC, Turner-Walker G, Moore KHS, Luisi P, Margaryan A, Martin MD, Ellegaard MR, Magnússon ÓÞ, Sigurðsson Á, Snorradóttir S, Magnúsdóttir DN, Laffoon JE, van Dorp L, Liu X, Moltke I, Ávila-Arcos MC, Schraiber JG, Rasmussen S, Juan D, Gelabert P, de-Dios T, Fotakis AK, Iraeta-Orbegozo M et al. (2022)
    The population genomic legacy of the second plague pandemic
    Curr Biol, 32 (21), 4743-4751.e6
    DOI 10.1016/j.cub.2022.09.023, PubMed 36182700
22. Gorunova L, Boye K, Panagopoulos I, Berner JM, Bjerkehagen B, Hompland I, Lobmaier I, Hølmebakk T, Hveem TS, Heim S, Micci F (2022)
    Cytogenetic and molecular analyses of 291 gastrointestinal stromal tumors: site-specific cytogenetic evolution as evidence of pathogenetic heterogeneity
    Oncotarget, 13, 508-517
    DOI 10.18632/oncotarget.28209, PubMed 35284037
23. Guldvik IJ, Braadland PR, Sivanesan S, Ramberg H, Kristensen G, Tennstedt P, Røder A, Schlomm T, Berge V, Eri LM, Lilleby W, Mills IG, Taskén KA (2022)
    Low Blood Levels of LRG1 Before Radical Prostatectomy Identify Patients with High Risk of Progression to Castration-resistant Prostate Cancer
    Eur Urol Open Sci, 45, 68-75
    DOI 10.1016/j.euros.2022.09.002, PubMed 36353660
24. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
    Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
    J Transl Med, 20 (1), 225
    DOI 10.1186/s12967-022-03432-5, PubMed 35568909
25. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
    Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
    J Transl Med, 20 (1), 317
    DOI 10.1186/s12967-022-03518-0, PubMed 35841045
26. Hodan R, Rodgers-Fouche L, Arora S, Dominguez-Valentin M, Kanth P, Katona BW, Mraz KA, Roberts ME, Vilar E, Soto-Azghani CM, Brand RE, Esplin ED, Perez K (2022)
    Patterns of germline and somatic testing after universal tumor screening for Lynch syndrome: A clinical practice survey of active members of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
    J Genet Couns, 31 (4), 949-955
    DOI 10.1002/jgc4.1567, PubMed 35218578
27. Høye E, Dagenborg VJ, Torgunrud A, Lund-Andersen C, Fretland ÅA, Lorenz S, Edwin B, Hovig E, Fromm B, Inderberg EM, Greiff V, Ree AH, Flatmark K (2022)
    T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases
    Gigascience, 12
    DOI 10.1093/gigascience/giad032, PubMed 37161965
28. Høye E, Fromm B, Böttger PHM, Domanska D, Torgunrud A, Lund-Andersen C, Abrahamsen TW, Fretland ÅA, Dagenborg VJ, Lorenz S, Edwin B, Hovig E, Flatmark K (2022)
    A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer
    NAR Cancer, 4 (1), zcab051
    DOI 10.1093/narcan/zcab051, PubMed 35047825
29. Li H, Engel C, Hoya M, Peterlongo P, Yannoukakos D, Livraghi L, Radice P, Thomassen M, Hansen TVO, Gerdes AM, Nielsen HR, Caputo SM, Zambelli A, Borg A, Solano A, Thomas A, Parsons MT, Antoniou AC, Leslie G, Yang X, Chenevix-Trench G, Caldes T, Kwong A, Pedersen IS, Lautrup CK et al. (2022)
    Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
    Genet Med, 24 (10), 2208
    DOI 10.1016/j.gim.2022.08.005, PubMed 36205748
30. Meltzer S, Negård A, Bakke KM, Hamre HM, Kersten C, Hofsli E, Guren MG, Sorbye H, Flatmark K, Ree AH (2022)
    Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
    Br J Cancer, 127 (12), 2227-2233
    DOI 10.1038/s41416-022-02004-0, PubMed 36229579
31. Metcalfe KA, Gronwald J, Tung NM, McCuaig JM, Eisen A, Elser C, Foulkes WD, Neuhausen SL, Senter L, Moller P, Bordeleau L, Fruscio R, Velsher L, Zakalik D, Olopade OI, Eng C, Pal T, Cullinane CA, Couch FJ, Kotsopoulos J, Sun P, Lubinski J, Narod SA (2022)
    The risks of cancer in older women with BRCA pathogenic variants: How far have we come?
    Cancer, 129 (6), 901-907
    DOI 10.1002/cncr.34615, PubMed 36571512
32. Misund K, Hofste Op Bruinink D, Coward E, Hoogenboezem RM, Rustad EH, Sanders MA, Rye M, Sponaas AM, van der Holt B, Zweegman S, Hovig E, Meza-Zepeda LA, Sundan A, Myklebost O, Sonneveld P, Waage A (2022)
    Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence
    Leukemia, 36 (7), 1887-1897
    DOI 10.1038/s41375-022-01597-y, PubMed 35643867
33. Mo T, Brandal SHB, Köhn-Luque A, Engebraaten O, Kristensen VN, Fleischer T, Hompland T, Seierstad T (2022)
    Quantification of Tumor Hypoxia through Unsupervised Modelling of Consumption and Supply Hypoxia MR Imaging in Breast Cancer
    Cancers (Basel), 14 (5)
    DOI 10.3390/cancers14051326, PubMed 35267636
34. Møller P (2022)
    The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
    Hered Cancer Clin Pract, 20 (1), 37
    DOI 10.1186/s13053-022-00243-z, PubMed 36411472
35. Møller P, Evans DG (2022)
    Inherited Cancer Genetic Epidemiology to Improve Precision Medicine
    J Clin Med, 11 (3)
    DOI 10.3390/jcm11030879, PubMed 35160330
36. Møller P, Seppälä T, Dowty JG, Haupt S, Dominguez-Valentin M, Sunde L, Bernstein I, Engel C, Aretz S, Nielsen M, Capella G, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Valle AD, Heinimann K et al. (2022)
    Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
    Hered Cancer Clin Pract, 20 (1), 36
    DOI 10.1186/s13053-022-00241-1, PubMed 36182917
37. Namløs HM, Skårn M, Ahmed D, Grad I, Andresen K, Kresse SH, Munthe E, Serra M, Scotlandi K, Llombart-Bosch A, Myklebost O, Lind GE, Meza-Zepeda LA (2022)
    miR-486-5p expression is regulated by DNA methylation in osteosarcoma
    BMC Genomics, 23 (1), 142
    DOI 10.1186/s12864-022-08346-6, PubMed 35172717
38. Ng MYW, Charsou C, Lapao A, Singh S, Trachsel-Moncho L, Schultz SW, Nakken S, Munson MJ, Simonsen A (2022)
    The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
    Nat Commun, 13 (1), 6283
    DOI 10.1038/s41467-022-33933-2, PubMed 36270994
39. Normann LS, Haugen MH, Aure MR, Kristensen VN, Mælandsmo GM, Sahlberg KK (2022)
    miR-101-5p Acts as a Tumor Suppressor in HER2-Positive Breast Cancer Cells and Improves Targeted Therapy
    Breast Cancer (Dove Med Press), 14, 25-39
    DOI 10.2147/BCTT.S338404, PubMed 35256859
40. Nunes-Xavier CE, Emaldi M, Guldvik IJ, Ramberg H, Taskén KA, Mælandsmo GM, Fodstad Ø, Llarena R, Pulido R, López JI (2022)
    Correlation of expression of Major Vault Protein with androgen receptor and immune checkpoint protein B7-H3, and with poor prognosis in prostate cancer
    Pathol Res Pract, 241, 154243
    DOI 10.1016/j.prp.2022.154243, PubMed 36481650
41. Nunes-Xavier CE, Mingo J, Emaldi M, Flem-Karlsen K, Mælandsmo GM, Fodstad Ø, Llarena R, López JI, Pulido R (2022)
    Heterogeneous Expression and Subcellular Localization of Pyruvate Dehydrogenase Complex in Prostate Cancer
    Front Oncol, 12, 873516
    DOI 10.3389/fonc.2022.873516, PubMed 35692804
42. Nyakas M, Fleten KG, Haugen MH, Engedal N, Sveen C, Farstad IN, Flørenes VA, Prasmickaite L, Mælandsmo GM, Seip K (2022)
    AXL inhibition improves BRAF-targeted treatment in melanoma
    Sci Rep, 12 (1), 5076
    DOI 10.1038/s41598-022-09078-z, PubMed 35332208
43. Pinto R, Hauge T, Jeanmougin M, Pharo HD, Kresse SH, Honne H, Winge SB, Five MB, Kumar T, Mala T, Hauge T, Johnson E, Lind GE (2022)
    Targeted genetic and epigenetic profiling of esophageal adenocarcinomas and non-dysplastic Barrett's esophagus
    Clin Epigenetics, 14 (1), 77
    DOI 10.1186/s13148-022-01287-7, PubMed 35701814
44. Pulido R, Nunes-Xavier CE (2022)
    Hopes on immunotherapy targeting B7-H3 in neuroblastoma
    Transl Oncol, 27, 101580
    DOI 10.1016/j.tranon.2022.101580, PubMed 36327699
45. Ree AH, Mælandsmo GM, Flatmark K, Russnes HG, Gómez Castañeda M, Aas E (2022)
    Cost-effectiveness of molecularly matched off-label therapies for end-stage cancer - the MetAction precision medicine study
    Acta Oncol, 61 (8), 955-962
    DOI 10.1080/0284186X.2022.2098053, PubMed 35943168
46. Sivanesan S, Taskén KA, Grytli HH (2022)
    Association of β-Blocker Use at Time of Radical Prostatectomy With Rate of Treatment for Prostate Cancer Recurrence
    JAMA Netw Open, 5 (1), e2145230
    DOI 10.1001/jamanetworkopen.2021.45230, PubMed 35080602
47. Sohlberg E, Pfefferle A, Heggernes Ask E, Tschan-Plessl A, Jacobs B, Netskar H, Lorenz S, Kanaya M, Kosugi-Kanaya M, Meinke S, Mörtberg A, Höglund P, Sundin M, Carlsson G, Palmblad J, Malmberg KJ (2022)
    Perturbed NK-cell homeostasis associated with disease severity in chronic neutropenia
    Blood, 139 (5), 704-716
    DOI 10.1182/blood.2021013233, PubMed 34699594
48. Stacchiotti S, Dürr HR, Schaefer IM, Woertler K, Haas R, Trama A, Caraceni A, Bajpai J, Baldi GG, Bernthal N, Blay JY, Boye K, Broto JM, Chen WT, Dei Tos PA, Desai J, Emhofer S, Eriksson M, Gronchi A, Gelderblom H, Hardes J, Hartmann W, Healey J, Italiano A, Jones RL et al. (2022)
    Best clinical management of tenosynovial giant cell tumour (TGCT): A consensus paper from the community of experts
    Cancer Treat Rev, 112, 102491
    DOI 10.1016/j.ctrv.2022.102491, PubMed 36502615
49. Søreng K, Pankiv S, Bergsmark C, Haugsten EM, Dahl AK, de la Ballina LR, Yamamoto A, Lystad AH, Simonsen A (2022)
    ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration
    J Cell Sci, 135 (4)
    DOI 10.1242/jcs.259138, PubMed 35099014
50. Taskén K, Russnes HEG, Aas E, Bjørge L, Blix ES, CONNECT Public–Private Partnership Consortium, Enerly E, Fagereng GL, Flobak Å, Gilje B, Gjertsen BT, Guren TK, Heix J, Hovig E, Hovland R, InPreD-Norway and National Molecular Tumor Board Consortium, IMPRESS-Norway Consortium, Lønning PE, Meza-Zepeda LA, Mæhle PM, Nilsen HL, Thoresen SØ, Widerberg K, Smeland S, Helland Å (2022)
    A national precision cancer medicine implementation initiative for Norway
    Nat Med, 28 (5), 885-887
    DOI 10.1038/s41591-022-01777-4, PubMed 35513529
51. Tellez-Gabriel M, Tekpli X, Reine TM, Hegge B, Nielsen SR, Chen M, Moi L, Normann LS, Busund LR, Calin GA, Mælandsmo GM, Perander M, Theocharis AD, Kolset SO, Knutsen E (2022)
    Serglycin Is Involved in TGF-β Induced Epithelial-Mesenchymal Transition and Is Highly Expressed by Immune Cells in Breast Cancer Tissue
    Front Oncol, 12, 868868
    DOI 10.3389/fonc.2022.868868, PubMed 35494005
52. Thomassen M, Mesman RLS, Hansen TVO, Menendez M, Rossing M, Esteban-Sánchez A, Tudini E, Törngren T, Parsons MT, Pedersen IS, Teo SH, Kruse TA, Møller P, Borg Å, Jensen UB, Christensen LL, Singer CF, Muhr D, Santamarina M, Brandao R, Andresen BS, Feng BJ, Canson D, Richardson ME, Karam R et al. (2022)
    Clinical, splicing, and functional analysis to classify BRCA2 exon 3 variants: Application of a points-based ACMG/AMP approach
    Hum Mutat, 43 (12), 1921-1944
    DOI 10.1002/humu.24449, PubMed 35979650
53. Torices L, Mingo J, Rodríguez-Escudero I, Fernández-Acero T, Luna S, Nunes-Xavier CE, López JI, Mercadillo F, Currás M, Urioste M, Molina M, Cid VJ, Pulido R (2022)
    Functional analysis of PTEN variants of unknown significance from PHTS patients unveils complex patterns of PTEN biological activity in disease
    Eur J Hum Genet, 31 (5), 568-577
    DOI 10.1038/s41431-022-01265-w, PubMed 36543932
54. Vaccaro CA, Soarez J, Dominguez-Valentin M, Pavicic WH (2022)
    Editorial: Advances in genetics and molecular diagnosis in colorectal, stomach, and pancreatic cancer
    Front Oncol, 12, 1104671
    DOI 10.3389/fonc.2022.1104671, PubMed 36601476
55. Venizelos A, Engebrethsen C, Deng W, Geisler J, Geisler S, Iversen GT, Aas T, Aase HS, Seyedzadeh M, Steinskog ES, Myklebost O, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Lønning PE, Knappskog S, Eikesdal HP (2022)
    Clonal evolution in primary breast cancers under sequential epirubicin and docetaxel monotherapy
    Genome Med, 14 (1), 86
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56. Xia YY, Gronwald J, Karlan B, Lubinski J, McCuaig JM, Brooks J, Moller P, Eisen A, Sun S, Senter L, Bordeleau L, Neuhausen SL, Singer CF, Tung N, Foulkes WD, Sun P, Narod SA, Kotsopoulos J, Hereditary Ovarian Cancer Clinical Study Group (2022)
    Contraceptive use and the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation
    Gynecol Oncol, 164 (3), 514-521
    DOI 10.1016/j.ygyno.2022.01.014, PubMed 35063280
57. Zavaleta E, Solis N, Palacios MI, Zevallos-Escobar LE, Corales EV, Bazo-Alvarez JC, Dominguez-Barrera C, Campos A, Wernhoff P, Ekstrøm PO, Møller P, Visnovska T, Hovig E, Balazar-Palacios J, Alvarez-Valenzuela K, Nakken S, Dominguez-Valentin M (2022)
    Genetic Characterization in High-Risk Individuals from a Low-Resource City of Peru
    Cancers (Basel), 14 (22)
    DOI 10.3390/cancers14225603, PubMed 36428697

Publications 2021

1. Andersson Y, Fleten KG, Abrahamsen TW, Reed W, Davidson B, Flatmark K (2021)
   Anti-Angiogenic Treatment in Pseudomyxoma Peritonei-Still a Strong Preclinical Rationale
   Cancers (Basel), 13 (11)
   DOI 10.3390/cancers13112819, PubMed 34198773
2. Barkovskaya A, Goodwin CM, Seip K, Hilmarsdottir B, Pettersen S, Stalnecker C, Engebraaten O, Briem E, Der CJ, Moestue SA, Gudjonsson T, Maelandsmo GM, Prasmickaite L (2021)
   Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen
   Mol Oncol, 15 (8), 2026-2045
   DOI 10.1002/1878-0261.12951, PubMed 33759347
3. Baxter JS, Johnson N, Tomczyk K, Gillespie A, Maguire S, Brough R, Fachal L, Michailidou K, Bolla MK, Wang Q, Dennis J, Ahearn TU, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Augustinsson A, Becher H, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bogdanova NV, Bojesen SE et al. (2021)
   Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element
   Am J Hum Genet, 108 (7), 1190-1203
   DOI 10.1016/j.ajhg.2021.05.013, PubMed 34146516
4. Boye K, Longhi A, Guren T, Lorenz S, Næss S, Pierini M, Taksdal I, Lobmaier I, Cesari M, Paioli A, Løndalen AM, Setola E, Hompland I, Meza-Zepeda LA, Sundby Hall K, Palmerini E (2021)
   Pembrolizumab in advanced osteosarcoma: results of a single-arm, open-label, phase 2 trial
   Cancer Immunol Immunother, 70 (9), 2617-2624
   DOI 10.1007/s00262-021-02876-w, PubMed 33580363
5. Cangiano M, Grudniewska M, Salji MJ, Nykter M, Jenster G, Urbanucci A, Granchi Z, Janssen B, Hamilton G, Leung HY, Beumer IJ (2021)
   Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the JMJD6 Regulon in Clinical Prostate Cancer
   Cancers (Basel), 13 (9)
   DOI 10.3390/cancers13092094, PubMed 33925994
6. Christensen SB, Simonsen HT, Engedal N, Nissen P, Møller JV, Denmeade SR, Isaacs JT (2021)
   From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development
   Prog Chem Org Nat Prod, 115, 59-114
   DOI 10.1007/978-3-030-64853-4_2, PubMed 33797641
7. Dagenborg VJ, Marshall SE, Grzyb K, Fretland ÅA, Lund-Iversen M, Mælandsmo GM, Ree AH, Edwin B, Yaqub S, Flatmark K (2021)
   Low Concordance Between T-Cell Densities in Matched Primary Tumors and Liver Metastases in Microsatellite Stable Colorectal Cancer
   Front Oncol, 11, 671629
   DOI 10.3389/fonc.2021.671629, PubMed 34178659
8. Dominguez-Valentin M, Plazzer JP, Sampson JR, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Macrae F, Winship IM, Thomas H, Evans DG, Burn J, Greenblatt M, de Vos Tot Nederveen Cappel WH, Sijmons RH, Nielsen M, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Lindblom A, Valle AD et al. (2021)
   No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study
   J Clin Med, 10 (13)
   DOI 10.3390/jcm10132856, PubMed 34203177
9. Ellingsen EB, Mangsbo SM, Hovig E, Gaudernack G (2021)
   Telomerase as a Target for Therapeutic Cancer Vaccines and Considerations for Optimizing Their Clinical Potential
   Front Immunol, 12, 682492
   DOI 10.3389/fimmu.2021.682492, PubMed 34290704
10. Engebraaten O, Yau C, Berg K, Borgen E, Garred Ø, Berstad MEB, Fremstedal ASV, DeMichele A, Veer LV', Esserman L, Weyergang A (2021)
    RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer
    Nat Commun, 12 (1), 6427
    DOI 10.1038/s41467-021-26018-z, PubMed 34741021
11. Erdélyi K, Ditrói T, Johansson HJ, Czikora Á, Balog N, Silwal-Pandit L, Ida T, Olasz J, Hajdú D, Mátrai Z, Csuka O, Uchida K, Tóvári J, Engebraten O, Akaike T, Børresen Dale AL, Kásler M, Lehtiö J, Nagy P (2021)
    Reprogrammed transsulfuration promotes basal-like breast tumor progression via realigning cellular cysteine persulfidation
    Proc Natl Acad Sci U S A, 118 (45)
    DOI 10.1073/pnas.2100050118, PubMed 34737229
12. Flatmark K, Torgunrud A, Fleten KG, Davidson B, Juul HV, Mensali N, Lund-Andersen C, Inderberg EM (2021)
    Peptide vaccine targeting mutated GNAS: a potential novel treatment for pseudomyxoma peritonei
    J Immunother Cancer, 9 (10)
    DOI 10.1136/jitc-2021-003109, PubMed 34711663
13. Fleten KG, Eksteen JJ, Mauseth B, Camilio KA, Vasskog T, Sveinbjørnsson B, Rekdal Ø, Mælandsmo GM, Flatmark K (2021)
    Oncolytic peptides DTT-205 and DTT-304 induce complete regression and protective immune response in experimental murine colorectal cancer
    Sci Rep, 11 (1), 6731
    DOI 10.1038/s41598-021-86239-6, PubMed 33762676
14. Georgiesh T, Namløs HM, Sharma N, Lorenz S, Myklebost O, Bjerkehagen B, Meza-Zepeda LA, Boye K (2021)
    Clinical and molecular implications of NAB2-STAT6 fusion variants in solitary fibrous tumour
    Pathology, 53 (6), 713-719
    DOI 10.1016/j.pathol.2020.11.010, PubMed 33745702
15. Grad I, Hanes R, Ayuda-Durán P, Kuijjer ML, Enserink JM, Meza-Zepeda LA, Myklebost O (2021)
    Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening
    PLoS One, 16 (3), e0248140
    DOI 10.1371/journal.pone.0248140, PubMed 33690666
16. Guerriero I, Ramberg H, Sagini K, Ramirez-Garrastacho M, Taskén KA, Llorente A (2021)
    Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells
    PLoS One, 16 (6), e0253828
    DOI 10.1371/journal.pone.0253828, PubMed 34191854
17. Guldvik IJ, Ekseth L, Kishan AU, Stensvold A, Inderberg EM, Lilleby W (2021)
    Circulating Tumor Cell Persistence Associates with Long-Term Clinical Outcome to a Therapeutic Cancer Vaccine in Prostate Cancer
    J Pers Med, 11 (7)
    DOI 10.3390/jpm11070605, PubMed 34206815
18. Gundersen S, Boddu S, Capella-Gutierrez S, Drabløs F, Fernández JM, Kompova R, Taylor K, Titov D, Zerbino D, Hovig E (2021)
    Recommendations for the FAIRification of genomic track metadata
    F1000Res, 10
    DOI 10.12688/f1000research.28449.1, PubMed 34249331
19. Haugen MH, Lingjærde OC, Hedenfalk I, Garred Ø, Borgen E, Loman N, Hatschek T, Børresen-Dale AL, Naume B, Mills GB, Mælandsmo GM, Engebraaten O (2021)
    Protein Signature Predicts Response to Neoadjuvant Treatment With Chemotherapy and Bevacizumab in HER2-Negative Breast Cancers
    JCO Precis Oncol, 5
    DOI 10.1200/PO.20.00086, PubMed 34036235
20. Hovda T, Hoff SR, Larsen M, Romundstad L, Sahlberg KK, Hofvind S (2021)
    True and Missed Interval Cancer in Organized Mammographic Screening: A Retrospective Review Study of Diagnostic and Prior Screening Mammograms
    Acad Radiol, 29 Suppl 1, S180-S191
    DOI 10.1016/j.acra.2021.03.022, PubMed 33926794
21. Hølmebakk T, Boye K (2021)
    ASO Author Reflections: How to Identify Patients at Genuinely High Risk of Recurrence from Localized Gastrointestinal Stromal Tumor of the Stomach?
    Ann Surg Oncol, 28 (11), 6846-6847
    DOI 10.1245/s10434-021-09608-5, PubMed 33687615
22. Hølmebakk T, Boye K (2021)
    Correction to: ASO Author Reflections: How to Identify Patients at Genuinely High Risk of Recurrence from Localized Gastrointestinal Stromal Tumor of the Stomach?
    Ann Surg Oncol, 28 (Suppl 3), 873
    DOI 10.1245/s10434-021-09939-3, PubMed 33829360
23. Hølmebakk T, Wiedswang AM, Meza-Zepeda LA, Hompland I, Lobmaier IVK, Berner JM, Stoldt S, Boye K (2021)
    Integrating Anatomical, Molecular and Clinical Risk Factors in Gastrointestinal Stromal Tumor of the Stomach
    Ann Surg Oncol, 28 (11), 6837-6845
    DOI 10.1245/s10434-021-09605-8, PubMed 33651216
24. Haakensen VD, Nowak AK, Ellingsen EB, Farooqi SJ, Bjaanæs MM, Horndalsveen H, Mcculloch T, Grundberg O, Cedres SM, Helland Å (2021)
    NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma
    J Transl Med, 19 (1), 232
    DOI 10.1186/s12967-021-02905-3, PubMed 34059094
25. Kanduri C, Sandve GK, Hovig E, De S, Layer RM (2021)
    Editorial: Genomic Colocalization and Enrichment Analyses
    Front Genet, 11, 617876
    DOI 10.3389/fgene.2020.617876, PubMed 33574832
26. Kang W, Fromm B, Houben AJ, Høye E, Bezdan D, Arnan C, Thrane K, Asp M, Johnson R, Biryukova I, Friedländer MR (2021)
    MapToCleave: High-throughput profiling of microRNA biogenesis in living cells
    Cell Rep, 37 (7), 110015
    DOI 10.1016/j.celrep.2021.110015, PubMed 34788611
27. Karvelsson ST, Sigurdsson A, Seip K, Grinde MT, Wang Q, Johannsson F, Mælandsmo GM, Moestue SA, Rolfsson O, Halldorsson S (2021)
    EMT-Derived Alterations in Glutamine Metabolism Sensitize Mesenchymal Breast Cells to mTOR Inhibition
    Mol Cancer Res, 19 (9), 1546-1558
    DOI 10.1158/1541-7786.MCR-20-0962, PubMed 34088869
28. Karvelsson ST, Wang Q, Hilmarsdottir B, Sigurdsson A, Moestue SA, Mælandsmo GM, Halldorsson S, Gudmundsson S, Rolfsson O (2021)
    Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer
    NPJ Syst Biol Appl, 7 (1), 36
    DOI 10.1038/s41540-021-00195-5, PubMed 34535676
29. Kim SJ, Lubinski J, Huzarski T, Møller P, Armel S, Karlan BY, Senter L, Eisen A, Foulkes WD, Singer CF, Tung N, Bordeleau L, Neuhausen SL, Olopade OI, Eng C, Weitzel JN, Fruscio R, Narod SA, Kotsopoulos J, Hereditary Ovarian Cancer Clinical Study Group (2021)
    Weight Gain and the Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers
    Cancer Epidemiol Biomarkers Prev, 30 (11), 2038-2043
    DOI 10.1158/1055-9965.EPI-21-0296, PubMed 34426412
30. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹
    Autophagy, 17 (1), 1-382
    DOI 10.1080/15548627.2020.1797280, PubMed 33634751
31. Krzyscik MA, Zakrzewska M, Sørensen V, Øy GF, Brunheim S, Haugsten EM, Mælandsmo GM, Wiedlocha A, Otlewski J (2021)
    Fibroblast Growth Factor 2 Conjugated with Monomethyl Auristatin E Inhibits Tumor Growth in a Mouse Model
    Biomacromolecules, 22 (10), 4169-4180
    DOI 10.1021/acs.biomac.1c00662, PubMed 34542998
32. Kukkonen K, Taavitsainen S, Huhtala L, Uusi-Makela J, Granberg KJ, Nykter M, Urbanucci A (2021)
    Chromatin and Epigenetic Dysregulation of Prostate Cancer Development, Progression, and Therapeutic Response
    Cancers (Basel), 13 (13)
    DOI 10.3390/cancers13133325, PubMed 34283056
33. Kværner AS, Birkeland E, Bucher-Johannessen C, Vinberg E, Nordby JI, Kangas H, Bemanian V, Ellonen P, Botteri E, Natvig E, Rognes T, Hovig E, Lyle R, Ambur OH, de Vos WM, Bultman S, Hjartåker A, Landberg R, Song M, Blix HS, Ursin G, Randel KR, de Lange T, Hoff G, Holme Ø et al. (2021)
    The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants
    BMC Cancer, 21 (1), 930
    DOI 10.1186/s12885-021-08640-8, PubMed 34407780
34. Larrinaga G, Calvete-Candenas J, Solano-Iturri JD, Martín AM, Pueyo A, Nunes-Xavier CE, Pulido R, Dorado JF, López JI, Angulo JC (2021)
    (Pro)renin Receptor Is a Novel Independent Prognostic Marker in Invasive Urothelial Carcinoma of the Bladder
    Cancers (Basel), 13 (22)
    DOI 10.3390/cancers13225642, PubMed 34830803
35. Larsen SG, Goscinski MA, Dueland S, Steigen SE, Hofsli E, Torgunrud A, Lund-Iversen M, Dagenborg VJ, Flatmark K, Sorbye H (2021)
    Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients
    Br J Cancer, 126 (5), 726-735
    DOI 10.1038/s41416-021-01620-6, PubMed 34887523
36. Lesueur F, Easton DF, Renault AL, Tavtigian SV, Bernstein JL, Kote-Jarai Z, Eeles RA, Plaseska-Karanfia D, Feliubadaló L, Spanish ATM working group, Arun B, Herold N, Versmold B, Schmutzler RK, GC-HBOC, Nguyen-Dumont T, Southey MC, Dorling L, Dunning AM, Ghiorzo P, Dalmasso BS, Cavaciuti E, Le Gal D, Roberts NJ, Dominguez-Valentin M et al. (2021)
    First international workshop of the ATM and cancer risk group (4-5 December 2019)
    Fam Cancer, 21 (2), 211-227
    DOI 10.1007/s10689-021-00248-y, PubMed 34125377
37. Li H, Engel C, de la Hoya M, Peterlongo P, Yannoukakos D, Livraghi L, Radice P, Thomassen M, Hansen TVO, Gerdes AM, Nielsen HR, Caputo SM, Zambelli A, Borg A, Solano A, Thomas A, Parsons MT, Antoniou AC, Leslie G, Yang X, Chenevix-Trench G, Caldes T, Kwong A, Pedersen IS, Lautrup CK et al. (2021)
    Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
    Genet Med, 24 (1), 119-129
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38. Luna S, Torices L, Mingo J, Amo L, Rodríguez-Escudero I, Ruiz-Ibarlucea P, Erramuzpe A, Cortés JM, Tejada MI, Molina M, Nunes-Xavier CE, López JI, Cid VJ, Pulido R (2021)
    A global analysis of the reconstitution of PTEN function by translational readthrough of PTEN pathogenic premature termination codons
    Hum Mutat, 42 (5), 551-566
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39. Lund-Andersen C, Torgunrud A, Fleten KG, Flatmark K (2021)
    Omics analyses in peritoneal metastasis-utility in the management of peritoneal metastases from colorectal cancer and pseudomyxoma peritonei: a narrative review
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40. Mariathasan AB, Boye K, Dueland S, Flatmark K, Larsen SG (2021)
    Metastases in locally advanced rectal cancer undergoing curatively intended treatment
    Eur J Surg Oncol, 47 (9), 2377-2383
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41. Mattingsdal M, Ebenesersdóttir SS, Moore KHS, Andreassen OA, Hansen TF, Werge T, Kockum I, Olsson T, Alfredsson L, Helgason A, Stefánsson K, Hovig E (2021)
    The genetic structure of Norway
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42. Meltzer S, Torgunrud A, Abrahamsson H, Solbakken AM, Flatmark K, Dueland S, Bakke KM, Bousquet PA, Negård A, Johansen C, Lyckander LG, Larsen FO, Schou JV, Redalen KR, Ree AH (2021)
    The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer
    Br J Cancer, 125 (2), 240-246
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43. Moghaddam S, Jalali A, O'Neill A, Murphy L, Gorman L, Reilly AM, Heffernan Á, Lynch T, Power R, O'Malley KJ, Taskèn KA, Berge V, Solhaug VA, Klocker H, Murphy TB, Watson RW (2021)
    Integrating Serum Biomarkers into Prediction Models for Biochemical Recurrence Following Radical Prostatectomy
    Cancers (Basel), 13 (16)
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44. Moller P, Sampson JR, Dominguez-Valentin M, Seppala TT (2021)
    Towards evidence-based personalised precision medicine for Lynch syndrome
    Lancet Oncol., 22 (9), E383
45. Morra A, Escala-Garcia M, Beesley J, Keeman R, Canisius S, Ahearn TU, Andrulis IL, Anton-Culver H, Arndt V, Auer PL, Augustinsson A, Beane Freeman LE, Becher H, Beckmann MW, Behrens S, Bojesen SE, Bolla MK, Brenner H, Brüning T, Buys SS, Caan B, Campa D, Canzian F, Castelao JE, Chang-Claude J et al. (2021)
    Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment
    Breast Cancer Res, 23 (1), 86
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46. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A (2021)
    GAK and PRKCD are positive regulators of PRKN-independent mitophagy
    Nat Commun, 12 (1), 6101
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47. Møller P, Sampson J, Dominguez-Valentin M, Burn J, Sunde L, Möslein G, Mecklin JP, Seppälä T (2021)
    Correction to: Letter to the Editor-Recent advances in Lynch syndrome
    Fam Cancer, 20 (2), 119
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48. Møller P, Sampson JR, Dominguez-Valentin M, Seppälä TT (2021)
    Towards evidence-based personalised precision medicine for Lynch syndrome
    Lancet Oncol, 22 (9), e383
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49. Nakken S, Lilleby W, Switlyk MD, Knudsen KE, Lilleby O, Zhao S, Kaveh F, Ekstrøm PO, Urbanucci A, Hovig E (2021)
    The Quandary of DNA-Based Treatment Assessment in De Novo Metastatic Prostate Cancer in the Era of Precision Oncology
    J Pers Med, 11 (5)
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50. Nakken S, Saveliev V, Hofmann O, Møller P, Myklebost O, Hovig E (2021)
    Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer
    Int J Cancer, 149 (11), 1955-1960
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51. Normann LS, Aure MR, Leivonen SK, Haugen MH, Hongisto V, Kristensen VN, Mælandsmo GM, Sahlberg KK (2021)
    MicroRNA in combination with HER2-targeting drugs reduces breast cancer cell viability in vitro
    Sci Rep, 11 (1), 10893
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52. Nunes-Xavier CE, Kildal W, Kleppe A, Danielsen HE, Waehre H, Llarena R, Maelandsmo GM, Fodstad Ø, Pulido R, López JI (2021)
    Immune checkpoint B7-H3 protein expression is associated with poor outcome and androgen receptor status in prostate cancer
    Prostate, 81 (12), 838-848
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53. Nunes-Xavier CE, Zaldumbide L, Mosteiro L, López-Almaraz R, García de Andoin N, Aguirre P, Emaldi M, Torices L, López JI, Pulido R (2021)
    Protein Tyrosine Phosphatases in Neuroblastoma: Emerging Roles as Biomarkers and Therapeutic Targets
    Front Cell Dev Biol, 9, 811297
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54. Oksvold MP, Berglund UW, Gad H, Bai B, Stokke T, Rein ID, Pham T, Sanjiv K, Øy GF, Norum JH, Smeland EB, Myklebust JH, Helleday T, Våtsveen TK (2021)
    Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma
    Sci Rep, 11 (1), 6317
    DOI 10.1038/s41598-021-85613-8, PubMed 33737576
55. Pandya AD, Iversen TG, Moestue S, Grinde MT, Mørch Ý, Snipstad S, Åslund AKO, Øy GF, Kildal W, Engebråten O, Sandvig K, Skotland T, Mælandsmo GM (2021)
    Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
    Nanomaterials (Basel), 11 (5)
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56. Park J, Choi JY, Choi J, Chung S, Song N, Park SK, Han W, Noh DY, Ahn SH, Lee JW, Kim MK, Jee SH, Wen W, Bolla MK, Wang Q, Dennis J, Michailidou K, Shah M, Conroy DM, Harrington PA, Mayes R, Czene K, Hall P, Teras LR, Patel AV et al. (2021)
    Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?
    Cancers (Basel), 13 (10)
    DOI 10.3390/cancers13102370, PubMed 34069208
57. Pavlović M, Scheffer L, Motwani K, Kanduri C, Kompova R, Vazov N, Waagan K, Bernal FLM, Costa AA, Corrie B, Akbar R, Al Hajj GS, Balaban G, Brusko TM, Chernigovskaya M, Christley S, Cowell LG, Frank R, Grytten I, Gundersen S, Haff IH, Hovig E, Hsieh PH, Klambauer G, Kuijjer ML et al. (2021)
    The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires
    Nat Mach Intell, 3 (11), 936-944
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58. Peneder P, Stütz AM, Surdez D, Krumbholz M, Semper S, Chicard M, Sheffield NC, Pierron G, Lapouble E, Tötzl M, Ergüner B, Barreca D, Rendeiro AF, Agaimy A, Boztug H, Engstler G, Dworzak M, Bernkopf M, Taschner-Mandl S, Ambros IM, Myklebost O, Marec-Bérard P, Burchill SA, Brennan B, Strauss SJ et al. (2021)
    Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden
    Nat Commun, 12 (1), 3230
    DOI 10.1038/s41467-021-23445-w, PubMed 34050156
59. Ramberg H, Richardsen E, de Souza GA, Rakaee M, Stensland ME, Braadland PR, Nygård S, Ögren O, Guldvik IJ, Berge V, Svindland A, Taskén KA, Andersen S (2021)
    Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
    Carcinogenesis, 42 (5), 685-693
    DOI 10.1093/carcin/bgab015, PubMed 33609362
60. Ramirez-Garrastacho M, Bajo-Santos C, Line A, Martens-Uzunova ES, de la Fuente JM, Moros M, Soekmadji C, Tasken KA, Llorente A (2021)
    Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: a decade of research
    Br J Cancer, 126 (3), 331-350
    DOI 10.1038/s41416-021-01610-8, PubMed 34811504
61. Schläfli AM, Tokarchuk I, Parejo S, Jutzi S, Berezowska S, Engedal N, Tschan MP (2021)
    ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells
    Sci Rep, 11 (1), 9011
    DOI 10.1038/s41598-021-87966-6, PubMed 33907223
62. Seppälä TT, Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2021)
    Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
    Eur J Cancer, 148, 124-133
    DOI 10.1016/j.ejca.2021.02.022, PubMed 33743481
63. Seppälä TT, Latchford A, Negoi I, Sampaio Soares A, Jimenez-Rodriguez R, Sánchez-Guillén L, Evans DG, Ryan N, Crosbie EJ, Dominguez-Valentin M, Burn J, Kloor M, Knebel Doeberitz MV, Duijnhoven FJBV, Quirke P, Sampson JR, Møller P, Möslein G, European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP) (2021)
    European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender
    Br J Surg, 108 (5), 484-498
    DOI 10.1002/bjs.11902, PubMed 34043773
64. Solis N, Zavaleta E, Wernhoff P, Dominguez-Barrera C, Dominguez-Valentin M (2021)
    Challenges to Bringing Personalized Medicine to a Low-Resource Setting in Peru
    Int J Environ Res Public Health, 18 (4)
    DOI 10.3390/ijerph18041470, PubMed 33557277
65. Stabell M, Sæther T, Røhr ÅK, Gabrielsen OS, Myklebost O (2021)
    Methylation-dependent SUMOylation of the architectural transcription factor HMGA2
    Biochem Biophys Res Commun, 552, 91-97
    DOI 10.1016/j.bbrc.2021.02.099, PubMed 33744765
66. Stjepanovic N, Lubinski J, Moller P, Randall Armel S, Foulkes WD, Tung N, Neuhausen SL, Kotsopoulos J, Sun P, Sun S, Eisen A, Narod SA, Hereditary Breast Cancer Clinical Study Group (2021)
    Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers
    Breast Cancer Res Treat, 187 (2), 515-523
    DOI 10.1007/s10549-020-06072-9, PubMed 33423179
67. Sveen A, Johannessen B, Eilertsen IA, Røsok BI, Gulla M, Eide PW, Bruun J, Kryeziu K, Meza-Zepeda LA, Myklebost O, Bjørnbeth BA, Skotheim RI, Nesbakken A, Lothe RA (2021)
    The expressed mutational landscape of microsatellite stable colorectal cancers
    Genome Med, 13 (1), 142
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68. Svendsen HA, Meling TR, Nygaard V, Waagene S, Russnes H, Juell S, Rogne SG, Pahnke J, Helseth E, Fodstad Ø, Maelandsmo GM (2021)
    Novel human melanoma brain metastasis models in athymic nude fox1^nu mice: Site-specific metastasis patterns reflecting their clinical origin
    Cancer Med, 10 (23), 8604-8613
    DOI 10.1002/cam4.4334, PubMed 34612023
69. Szybowska P, Kostas M, Wesche J, Haugsten EM, Wiedlocha A (2021)
    Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling
    Cells, 10 (6)
    DOI 10.3390/cells10061342, PubMed 34071546
70. Sønstevold T, Engedal N, Torgersen ML (2021)
    Perturbation of Cellular Redox Homeostasis Dictates Divergent Effects of Polybutyl Cyanoacrylate (PBCA) Nanoparticles on Autophagy
    Cells, 10 (12)
    DOI 10.3390/cells10123432, PubMed 34943939
71. Sørensen O, Andersen AM, Larsen SG, Giercksky KE, Flatmark K (2021)
    Correction to: Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of highgrade pseudomyxoma peritonei
    Clin Exp Metastasis, 38 (2), 253
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72. Tamhane T, Njenga RW, Burden RE, Bueth H, Maelandsmo GM, Haugen MH, Scott CJ, Brix K (2021)
    Trafficking of Full-Length and N-Terminally Truncated Cathepsin B in Human Colorectal Carcinoma Cells
    Appl. Sci.-Basel, 11 (24), 11936
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73. Thorgersen EB, Asvall J, Frøysnes IS, Schjalm C, Larsen SG, Dueland S, Andersson Y, Fodstad Ø, Mollnes TE, Flatmark K (2021)
    Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
    Ann Surg Oncol, 28 (9), 5252-5262
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74. Thorgersen EB, Flatmark K (2021)
    ASO Author Reflections: The Peritoneum is an Active Immunological Compartment
    Ann Surg Oncol, 28 (9), 5263-5264
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75. Torices L, de Las Heras J, Arango-Lasprilla JC, Cortés JM, Nunes-Xavier CE, Pulido R (2021)
    MMADHC premature termination codons in the pathogenesis of cobalamin D disorder: Potential of translational readthrough reconstitution
    Mol Genet Metab Rep, 26, 100710
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76. Taavitsainen S, Engedal N, Cao S, Handle F, Erickson A, Prekovic S, Wetterskog D, Tolonen T, Vuorinen EM, Kiviaho A, Nätkin R, Häkkinen T, Devlies W, Henttinen S, Kaarijärvi R, Lahnalampi M, Kaljunen H, Nowakowska K, Syvälä H, Bläuer M, Cremaschi P, Claessens F, Visakorpi T, Tammela TLJ, Murtola T et al. (2021)
    Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
    Nat Commun, 12 (1), 5307
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77. Valsalakumari R, Yadava SK, Szwed M, Pandya AD, Mælandsmo GM, Torgersen ML, Iversen TG, Skotland T, Sandvig K, Giri J (2021)
    Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
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78. van der Zanden TM, Mooij MG, Vet NJ, Neubert A, Rascher W, Lagler FB, Male C, Grytli H, Halvorsen T, de Hoog M, de Wildt SN (2021)
    Benefit-Risk Assessment of Off-Label Drug Use in Children: The Bravo Framework
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79. Vikan AK, Kostas M, Haugsten EM, Selbo PK, Wesche J (2021)
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80. Wang N, Bai D, Kristiansen E, Deng R, Zhang S (2021)
    AKIP1 promotes tumor progression by cancer-related pathways and predicts prognosis in tongue squamous cell carcinoma
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    Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation
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    Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial
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Publications 2020

1. Aghayan DL, Kazaryan AM, Dagenborg VJ, Røsok BI, Fagerland MW, Waaler Bjørnelv GM, Kristiansen R, Flatmark K, Fretland ÅA, Edwin B, OSLO-COMET Survival Study Collaborators (2020)
   Long-Term Oncologic Outcomes After Laparoscopic Versus Open Resection for Colorectal Liver Metastases : A Randomized Trial
   Ann Intern Med, 174 (2), 175-182
   DOI 10.7326/M20-4011, PubMed 33197213
2. Ahadova A, Seppälä TT, Engel C, Gallon R, Burn J, Holinski-Feder E, Steinke-Lange V, Möslein G, Nielsen M, Ten Broeke SW, Laghi L, Dominguez-Valentin M, Capella G, Macrae F, Scott R, Hüneburg R, Nattermann J, Hoffmeister M, Brenner H, Bläker H, von Knebel Doeberitz M, Sampson JR, Vasen H, Mecklin JP, Møller P et al. (2020)
   The "unnatural" history of colorectal cancer in Lynch syndrome: Lessons from colonoscopy surveillance
   Int J Cancer, 148 (4), 800-811
   DOI 10.1002/ijc.33224, PubMed 32683684
3. Álvarez K, Orellana P, De la Fuente M, Canales T, Pinto E, Heine C, Solar B, Hurtado C, Møller P, Kronberg U, Zarate AJ, Dominguez-Valentin M, López-Köstner F (2020)
   Spectrum and Frequency of Tumors, Cancer Risk and Survival in Chilean Families with Lynch Syndrome: Experience of the Implementation of a Registry
   J Clin Med, 9 (6)
   DOI 10.3390/jcm9061861, PubMed 32549215
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