Publications Department. of Tumor Biology

Publications published since 1971 from OUS - Department of Tumor Biology

1416 publications found (only first 1000 shown)

Publications 2024

  1. Akdeniz BC, Frei O, Hagen E, Filiz TT, Karthikeyan S, Pasman J, Jangmo A, Bergstedt J, Shorter JR, Zetterberg R, Meijsen J, Sønderby IE, Buil A, Tesli M, Lu Y, Sullivan P, Andreassen OA, Hovig E (2024)
    COSGAP: COntainerized Statistical Genetics Analysis Pipelines
    Bioinform Adv, 4 (1), vbae067
    DOI 10.1093/bioadv/vbae067, PubMed 38808072
  2. Akdeniz BC, Frei O, Shadrin A, Vetrov D, Kropotov D, Hovig E, Andreassen OA, Dale AM (2024)
    Finemap-MiXeR: A variational Bayesian approach for genetic finemapping
    PLoS Genet, 20 (8), e1011372
    DOI 10.1371/journal.pgen.1011372, PubMed 39146375
  3. Angulo JC, Larrinaga G, Lecumberri D, Iturregui AM, Solano-Iturri JD, Lawrie CH, Armesto M, Dorado JF, Nunes-Xavier CE, Pulido R, Manini C, López JI (2024)
    Predicting Survival of Metastatic Clear Cell Renal Cell Cancer Treated with VEGFR-TKI-Based Sequential Therapy
    Cancers (Basel), 16 (16)
    DOI 10.3390/cancers16162786, PubMed 39199559
  4. Bai B, Wise JF, Vodák D, Nakken S, Sharma A, Blaker YN, Brodtkorb M, Hilden V, Trøen G, Ren W, Lorenz S, Lawrence MS, Myklebost O, Kimby E, Pan-Hammarström Q, Steen CB, Meza-Zepeda LA, Beiske K, Smeland EB, Hovig E, Lingjærde OC, Holte H, Myklebust JH (2024)
    Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma
    Blood Cancer J, 14 (1), 147
    DOI 10.1038/s41408-024-01124-5, PubMed 39191762
  5. Bischof K, Cremaschi A, Eroukhmanoff L, Landskron J, Flage-Larsen LL, Gade A, Bjørge L, Urbanucci A, Taskén K (2024)
    Patient-derived acellular ascites fluid affects drug responses in ovarian cancer cell lines through the activation of key signalling pathways
    Mol Oncol (in press)
    DOI 10.1002/1878-0261.13726, PubMed 39245677
  6. Bucher-Johannessen C, Senthakumaran T, Avershina E, Birkeland E, Hoff G, Bemanian V, Tunsjø H, Rounge TB (2024)
    Species-level verification of Phascolarctobacterium association with colorectal cancer
    mSystems, 9 (10), e0073424
    DOI 10.1128/msystems.00734-24, PubMed 39287376
  7. Cavanaugh D, Urbanucci A, Mohamed NE, Tewari AK, Figueiro M, Kyprianou N (2024)
    Link between circadian rhythm and benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS)
    Prostate, 84 (5), 417-425
    DOI 10.1002/pros.24656, PubMed 38193363
  8. Dagenborg VJ, Brudvik KW, Lund-Andersen C, Torgunrud A, Lund-Iversen M, Flatmark K, Larsen SG, Yaqub S (2024)
    Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy and Liver Resection is a Treatment Option for Patients With Peritoneal and Liver Metastases From Colorectal Cancer
    Ann Surg, 280 (5), 745-752
    DOI 10.1097/SLA.0000000000006492, PubMed 39185557
  9. Davidson B, Holth A, Lindemann K, Zahl Eriksson AG, Nilsen TA, Torgunrud A (2024)
    Molecular characteristics of tubo-ovarian carcinosarcoma at different anatomic locations
    Virchows Arch (in press)
    DOI 10.1007/s00428-024-03821-9, PubMed 38733380
  10. Edsjö A, Russnes HG, Lehtiö J, Tamborero D, Hovig E, Stenzinger A, Rosenquist R, PCM4EU consortium (2024)
    High-throughput molecular assays for inclusion in personalised oncology trials - State-of-the-art and beyond
    J Intern Med, 295 (6), 785-803
    DOI 10.1111/joim.13785, PubMed 38698538
  11. Egeland EV, Seip K, Skourti E, Øy GF, Pettersen SJ, Pandya AD, Dahle MA, Haugen MH, Kristian A, Nakken S, Engebraaten O, Mælandsmo GM, Prasmickaite L (2024)
    The SRC-family serves as a therapeutic target in triple negative breast cancer with acquired resistance to chemotherapy
    Br J Cancer, 131 (10), 1656-1667
    DOI 10.1038/s41416-024-02875-5, PubMed 39390250
  12. Ellegaard MR, Ebenesersdóttir SS, Moore KHS, Petersén A, Vågene ÅJ, Bieker VC, Denham SD, Cavalleri GL, Gilbert E, Werge T, Hansen TF, Kockum I, Alfredsson L, Olsson T, Hovig E, Gilbert MTP, Stefánsson K, Stenøien HK, Helgason A, Martin MD (2024)
    Corroborating written history with ancient DNA: The case of the Well-man described in an Old Norse saga
    iScience, 27 (11), 111076
    DOI 10.1016/j.isci.2024.111076, PubMed 39620136
  13. Emaldi M, Alamillo-Maeso P, Rey-Iborra E, Mosteiro L, Lecumberri D, Pulido R, López JI, Nunes-Xavier CE (2024)
    A functional role for glycosylated B7-H5/VISTA immune checkpoint protein in metastatic clear cell renal cell carcinoma
    iScience, 27 (9), 110587
    DOI 10.1016/j.isci.2024.110587, PubMed 39262813
  14. Emaldi M, Rey-Iborra E, Marín Á, Mosteiro L, Lecumberri D, Øyjord T, Roncier N, Mælandsmo GM, Angulo JC, Errarte P, Larrinaga G, Pulido R, López JI, Nunes-Xavier CE (2024)
    Impact of B7-H3 expression on metastasis, immune exhaustion and JAK/STAT and PI3K/AKT pathways in clear cell renal cell carcinoma
    Oncoimmunology, 13 (1), 2419686
    DOI 10.1080/2162402X.2024.2419686, PubMed 39621555
  15. Esperon P, Neffa F, Pavicic W, Spirandelli F, Alvarez K, Mullins MJ, Rossi BM, Góngora E Silva RF, Vaccaro C, Lopéz-Köstner F, Rugeles J, Valle AD, Dominguez-Valentin M (2024)
    A comprehensive characterization of the spectrum of MUTYH germline pathogenic variants in Latin America
    Fam Cancer, 23 (4), 507-513
    DOI 10.1007/s10689-024-00382-3, PubMed 38687439
  16. Fleischer T, Haugen MH, Ankill J, Silwal-Pandit L, Børresen-Dale AL, Hedenfalk I, Hatschek T, Tost J, Engebraaten O, Kristensen VN (2024)
    An integrated omics approach highlights how epigenetic events can explain and predict response to neoadjuvant chemotherapy and bevacizumab in breast cancer
    Mol Oncol, 18 (8), 2042-2059
    DOI 10.1002/1878-0261.13656, PubMed 38671580
  17. Foote JB, Mattox TE, Keeton AB, Chen X, Smith F, Berry KL, Holmes T, Wang J, Huang CH, Ward AB, Mitra AK, Ramirez-Alcantara V, Hardy C, Fleten KG, Flatmark K, Yoon KJ, Sarvesh S, Nagaraju GP, Bandi DSR, Maxuitenko YY, Valiyaveettil J, Carstens JL, Buchsbaum DJ, Yang J, Zhou G et al. (2024)
    A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer
    bioRxiv
    DOI 10.1101/2023.05.17.541233, PubMed 38328254
  18. Guldvik IJ, Ramberg H, Kristensen G, Røder A, Mills IG, Lilleby W, Taskén KA (2024)
    Systemic interrogation of immune-oncology-related proteins in patients with locally advanced prostate cancer undergoing androgen deprivation and intensity-modulated radiotherapy
    World J Urol, 42 (1), 95
    DOI 10.1007/s00345-024-04787-8, PubMed 38386171
  19. Heinrich MC, Jones RL, George S, Gelderblom H, Schöffski P, von Mehren M, Zalcberg JR, Kang YK, Razak AA, Trent J, Attia S, Le Cesne A, Siontis BL, Goldstein D, Boye K, Sanchez C, Steeghs N, Rutkowski P, Druta M, Serrano C, Somaiah N, Chi P, Reichmann W, Sprott K, Achour H et al. (2024)
    Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial
    Nat Med, 30 (2), 498-506
    DOI 10.1038/s41591-023-02734-5, PubMed 38182785
  20. Istvan P, Birkeland E, Avershina E, Kværner AS, Bemanian V, Pardini B, Tarallo S, de Vos WM, Rognes T, Berstad P, Rounge TB (2024)
    Exploring the gut DNA virome in fecal immunochemical test stool samples reveals associations with lifestyle in a large population-based study
    Nat Commun, 15 (1), 1791
    DOI 10.1038/s41467-024-46033-0, PubMed 38424056
  21. Ivarsdottir EV, Gudmundsson J, Tragante V, Sveinbjornsson G, Kristmundsdottir S, Stacey SN, Halldorsson GH, Magnusson MI, Oddsson A, Walters GB, Sigurdsson A, Saevarsdottir S, Beyter D, Thorleifsson G, Halldorsson BV, Melsted P, Stefansson H, Jonsdottir I, Sørensen E, Pedersen OB, Erikstrup C, Bøgsted M, Pøhl M, Røder A, Stroomberg HV et al. (2024)
    Gene-based burden tests of rare germline variants identify six cancer susceptibility genes
    Nat Genet, 56 (11), 2422-2433
    DOI 10.1038/s41588-024-01966-6, PubMed 39472694
  22. Kandathil SA, Akhondi A, Kadletz-Wanke L, Heiduschka G, Engedal N, Brkic FF (2024)
    The dual role of autophagy in HPV-positive head and neck squamous cell carcinoma: a systematic review
    J Cancer Res Clin Oncol, 150 (2), 56
    DOI 10.1007/s00432-023-05514-3, PubMed 38291202
  23. Katona BW, Lubinski J, Pal T, Huzarski T, Foulkes WD, Moller P, Eisen A, Randall Armel S, Neuhausen SL, Raj R, Aeilts A, Singer CF, Bordeleau L, Karlan B, Olopade O, Tung N, Zakalik D, Kotsopoulos J, Fruscio R, Eng C, Sun P, Narod SA, Hereditary Breast Cancer Clinical Study Group (2024)
    The incidence of pancreatic cancer in women with a BRCA1 or BRCA2 mutation
    Cancer (in press)
    DOI 10.1002/cncr.35666, PubMed 39611336
  24. Kiviaho A, Eerola SK, Kallio HML, Andersen MK, Hoikka M, Tiihonen AM, Salonen I, Spotbeen X, Giesen A, Parker CTA, Taavitsainen S, Hantula O, Marttinen M, Hermelo I, Ismail M, Midtbust E, Wess M, Devlies W, Sharma A, Krossa S, Häkkinen T, Afyounian E, Vandereyken K, Kint S, Kesseli J et al. (2024)
    Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer
    Nat Commun, 15 (1), 9949
    DOI 10.1038/s41467-024-54364-1, PubMed 39550375
  25. Kotsopoulos J, Gronwald J, Huzarski T, Møller P, Pal T, McCuaig JM, Singer CF, Karlan BY, Aeilts A, Eng C, Eisen A, Bordeleau L, Foulkes WD, Tung N, Couch FJ, Fruscio R, Neuhausen SL, Zakalik D, Cybulski C, Metcalfe K, Olopade OI, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2024)
    Bilateral Oophorectomy and All-Cause Mortality in Women With BRCA1 and BRCA2 Sequence Variations
    JAMA Oncol, 10 (4), 484-492
    DOI 10.1001/jamaoncol.2023.6937, PubMed 38421677
  26. Kotsopoulos J, Lubinski J, Huzarski T, Bychkovsky BL, Moller P, Kim RH, Tung N, Eisen A, Foulkes W, Singer CF, Aeilts A, Neuhausen SL, Bordeleau L, Karlan B, Fruscio R, Eng C, Olopade O, Zakalik D, Couch F, Y Cajal TR, Sun P, Gronwald J, Narod SA (2024)
    Incidence of endometrial cancer in BRCA mutation carriers
    Gynecol Oncol, 189, 148-155
    DOI 10.1016/j.ygyno.2024.07.687, PubMed 39173195
  27. Kurganovs NJ, Engedal N (2024)
    To eat or not to eat: a critical review on the role of autophagy in prostate carcinogenesis and prostate cancer therapeutics
    Front Pharmacol, 15, 1419806
    DOI 10.3389/fphar.2024.1419806, PubMed 38910881
  28. Lamsal A, Andersen SB, Johansson I, Desgarnier MD, Wolowczyk C, Engedal N, Vietri M, Bjørkøy G, Giambelluca MS, Pettersen K (2024)
    Elucidating the power of arginine restriction: taming type I interferon response in breast cancer via selective autophagy
    Cell Commun Signal, 22 (1), 481
    DOI 10.1186/s12964-024-01858-6, PubMed 39380098
  29. Lubinski J, Kotsopoulos J, Moller P, Pal T, Eisen A, Peck L, Karlan BY, Aeilts A, Eng C, Bordeleau L, Foulkes WD, Tung N, Couch FJ, Fruscio R, Ramon Y Cajal T, Singer CF, Neuhausen SL, Zakalik D, Cybulski C, Gronwald J, Huzarski T, Stempa K, Dungan J, Cullinane C, Olopade OI et al. (2024)
    MRI Surveillance and Breast Cancer Mortality in Women With BRCA1 and BRCA2 Sequence Variations
    JAMA Oncol, 10 (4), 493-499
    DOI 10.1001/jamaoncol.2023.6944, PubMed 38421676
  30. Lund-Andersen C, Torgunrud A, Kanduri C, Dagenborg VJ, Frøysnes IS, Larsen MM, Davidson B, Larsen SG, Flatmark K (2024)
    Novel drug resistance mechanisms and drug targets in BRAF-mutated peritoneal metastasis from colorectal cancer
    J Transl Med, 22 (1), 646
    DOI 10.1186/s12967-024-05467-2, PubMed 38982444
  31. Mattavelli D, Wichmann G, Smussi D, Paderno A, Plana MS, Mesia RN, Compagnoni M, Medda A, Chiocca S, Calza S, Zhan Y, Rognoni C, Tarricone R, Stucchi E, Lorini L, Gurizzan C, Khelik K, Hovig E, Dietz A, Piazza C, Bossi P (2024)
    Is precision medicine the solution to improve organ preservation in laryngeal/hypopharyngeal cancer? A position paper by the Preserve Research Group
    Front Oncol, 14, 1433333
    DOI 10.3389/fonc.2024.1433333, PubMed 39165689
  32. Møller P, Haupt S, Ahadova A, Kloor M, Sampson JR, Sunde L, Seppälä T, Burn J, Bernstein I, Capella G, Evans DG, Lindblom A, Winship I, Macrae F, Katz L, Laish I, Vainer E, Monahan K, Half E, Horisberger K, da Silva LA, Heuveline V, Therkildsen C, Lautrup C, Klarskov LL et al. (2024)
    Incidences of colorectal adenomas and cancers under colonoscopy surveillance suggest an accelerated "Big Bang" pathway to CRC in three of the four Lynch syndromes
    Hered Cancer Clin Pract, 22 (1), 6
    DOI 10.1186/s13053-024-00279-3, PubMed 38741120
  33. Møller P, Hovig E (2024)
    Genetic testing for prevention and treatment of cancer
    Tidsskr Nor Laegeforen, 144 (13)
    DOI 10.4045/tidsskr.24.0434, PubMed 39498653
  34. Møller P, Seppälä TT, Dominguez-Valentin M, Sampson J (2024)
    Commentary on Estimating cancer risk in carriers of Lynch syndrome variants in UK Biobank
    J Med Genet (in press)
    DOI 10.1136/jmg-2024-110385, PubMed 39375027
  35. Narod SA, Gronwald J, Karlan B, Moller P, Huzarski T, Tung N, Aeilts A, Eisen A, Armel SR, Singer CF, Foulkes WD, Neuhausen SL, Olopade O, Pal T, Fruscio R, Metcalfe K, Raj R, Jacobson M, Sun P, Lubinski J, Kotsopoulos J (2024)
    Incidence of peritoneal cancer after oophorectomy among BRCA1 and BRCA2 mutation carriers
    J Natl Cancer Inst, 116 (11), 1753-1760
    DOI 10.1093/jnci/djae151, PubMed 38937272
  36. Niehusmann P, Leske H, Nygaard V, Russnes HG, Zhao S, Latysheva A, Straume Wiig U, Stankuniene B, Ulvmoen A (2024)
    Desmoplastic non-infantile ganglioglioma mimicking diffuse leptomeningeal glioneuronal tumor: precision diagnostics and therapeutic implications
    Acta Oncol, 63, 392-394
    DOI 10.2340/1651-226X.2024.31720, PubMed 38779936
  37. Nikolski M, Hovig E, Al-Shahrour F, Blomberg N, Scollen S, Valencia A, Saunders G (2024)
    Roadmap for a European cancer data management and precision medicine infrastructure
    Nat Cancer, 5 (3), 367-372
    DOI 10.1038/s43018-023-00717-6, PubMed 38321342
  38. Nunes-Xavier CE (2024)
    Editorial: Co-inhibitory immune checkpoint proteins as biomarkers and therapeutic targets in cancer
    Transl Oncol, 47, 102005
    DOI 10.1016/j.tranon.2024.102005, PubMed 39034056
  39. Patrick-Brown TDJH, Barratt-Due A, Trøseid M, Dyrhol-Riise AM, Nezvalova-Henriksen K, Kåsine T, Aukrust P, Olsen IC, NOR Solidarity consortium (2024)
    The effects of remdesivir on long-term symptoms in patients hospitalised for COVID-19: a pre-specified exploratory analysis
    Commun Med (Lond), 4 (1), 231
    DOI 10.1038/s43856-024-00650-4, PubMed 39533001
  40. Patrick-Brown TDJH, Bourner J, Kali S, Trøseid M, Yazdanpanah Y, Olliaro P, Olsen IC (2024)
    Experiences and challenges with the new European Clinical Trials Regulation
    Trials, 25 (1), 3
    DOI 10.1186/s13063-023-07869-x, PubMed 38167484
  41. Pulido R, López JI, Nunes-Xavier CE (2024)
    B7-H3: a robust target for immunotherapy in prostate cancer
    Trends Cancer, 10 (7), 584-587
    DOI 10.1016/j.trecan.2024.05.003, PubMed 38839545
  42. Ranji P, Jonasson E, Andersson L, Filges S, Luna Santamaría M, Vannas C, Dolatabadi S, Gustafsson A, Myklebost O, Håkansson J, Fagman H, Landberg G, Åman P, Ståhlberg A (2024)
    Deciphering the role of FUS::DDIT3 expression and tumor microenvironment in myxoid liposarcoma development
    J Transl Med, 22 (1), 389
    DOI 10.1186/s12967-024-05211-w, PubMed 38671504
  43. Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Chèneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A (2024)
    JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
    Nucleic Acids Res, 52 (D1), D174-D182
    DOI 10.1093/nar/gkad1059, PubMed 37962376
  44. Ree AH, Høye E, Esbensen Y, Beitnes AR, Negård A, Bernklev L, Tetlie LK, Fretland ÅA, Hamre HM, Kersten C, Hofsli E, Guren MG, Sorbye H, Nilsen HL, Flatmark K, Meltzer S (2024)
    Complete response of metastatic microsatellite-stable BRAF V600E colorectal cancer to first-line oxaliplatin-based chemotherapy and immune checkpoint blockade
    Oncoimmunology, 13 (1), 2372886
    DOI 10.1080/2162402X.2024.2372886, PubMed 38952672
  45. Ree AH, Šaltytė Benth J, Hamre HM, Kersten C, Hofsli E, Guren MG, Sorbye H, Johansen C, Negård A, Bjørnetrø T, Nilsen HL, Berg JP, Flatmark K, Meltzer S (2024)
    First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer-the randomised METIMMOX trial
    Br J Cancer, 130 (12), 1921-1928
    DOI 10.1038/s41416-024-02696-6, PubMed 38664577
  46. Reppe S, Gundersen S, Sandve GK, Wang Y, Andreassen OA, Medina-Gomez C, Rivadeneira F, Utheim TP, Hovig E, Gautvik KM (2024)
    Identification of Transcripts with Shared Roles in the Pathogenesis of Postmenopausal Osteoporosis and Cardiovascular Disease
    Int J Mol Sci, 25 (10)
    DOI 10.3390/ijms25105554, PubMed 38791593
  47. Schiffer PH, Natsidis P, Leite DJ, Robertson HE, Lapraz F, Marlétaz F, Fromm B, Baudry L, Simpson F, Høye E, Zakrzewski AC, Kapli P, Hoff KJ, Müller S, Marbouty M, Marlow H, Copley RR, Koszul R, Sarkies P, Telford MJ (2024)
    Insights into early animal evolution from the genome of the xenacoelomorph worm Xenoturbella bocki
    Elife, 13
    DOI 10.7554/eLife.94948, PubMed 39109482
  48. Soarez J, Vaccaro CA, Dominguez-Valentin M, Pavicic WH (2024)
    Editorial: Advances in genetics and molecular diagnosis in colorectal, stomach, and pancreatic cancer vol II
    Front Oncol, 14, 1448183
    DOI 10.3389/fonc.2024.1448183, PubMed 39050580
  49. Sveen A, Johannessen B, Klokkerud SM, Kraggerud SM, Meza-Zepeda LA, Bjørnslett M, Bischof K, Myklebost O, Taskén K, Skotheim RI, Dørum A, Davidson B, Lothe RA (2024)
    Evolutionary mode and timing of dissemination of high-grade serous carcinomas
    JCI Insight, 9 (3)
    DOI 10.1172/jci.insight.170423, PubMed 38175731
  50. Torices L, Nunes-Xavier CE, Mingo J, Luna S, Erramuzpe A, Cortés JM, Pulido R (2024)
    Induction of Translational Readthrough on Protein Tyrosine Phosphatases Targeted by Premature Termination Codon Mutations in Human Disease
    Methods Mol Biol, 2743, 1-19
    DOI 10.1007/978-1-0716-3569-8_1, PubMed 38147205
  51. Torices L, Nunes-Xavier CE, Pulido R (2024)
    Potentiation by Protein Synthesis Inducers of Translational Readthrough of Pathogenic Premature Termination Codons in PTEN Isoforms
    Cancers (Basel), 16 (16)
    DOI 10.3390/cancers16162836, PubMed 39199607
  52. Valsalakumari R, Pandya AD, Prasmickaite L, Kvalvaag A, Myrann AG, Åslund AKO, Kjos MS, Fontecha-Cuenca C, Haroon HB, Ribeiro ARS, Horejs-Hoeck J, Moghimi SM, Mørch Ý, Skotland T, Sandvig K, Mælandsmo GM, Iversen TG (2024)
    Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants
    Int J Nanomedicine, 19, 3009-3029
    DOI 10.2147/IJN.S450283, PubMed 38562610
  53. van der Werf-'t Lam AS, Rodriguez-Girondo M, Villasmil M, Tops CM, van Hest L, Gille HJP, Duijkers FAM, Wagner A, Eikenboom E, Letteboer TGW, de Jong MM, Bajwa-Ten Broeke SW, Bleeker F, Gomez Garcia EB, Dominguez-Valentin M, Møller P, Suerink M, Nielsen M (2024)
    Delineating genotype and parent-of-origin effect on the phenotype in MSH6-associated Lynch syndrome
    Genes Chromosomes Cancer, 63 (5), e23237
    DOI 10.1002/gcc.23237, PubMed 38722212
  54. Wiig JN, Dagenborg VJ, Larsen SG (2024)
    Ten-year survival and pattern of recurrence in patients with locally recurrent rectal or sigmoid cancer undergoing resection
    Colorectal Dis (in press)
    DOI 10.1111/codi.17226, PubMed 39635974
  55. Zhou Y, Ray PS, Zhu J, Stein F, Rettel M, Sekaran T, Sahadevan S, Perez-Perri JI, Roth EK, Myklebost O, Meza-Zepeda LA, von Deimling A, Fu C, Brosig AN, Boye K, Nathrath M, Blattmann C, Lehner B, Hentze MW, Kulozik AE (2024)
    Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma
    Nat Commun, 15 (1), 2810
    DOI 10.1038/s41467-024-47031-y, PubMed 38561347

Publications 2023

  1. Akdeniz BC, Mattingsdal M, Dominguez-Valentin M, Frei O, Shadrin A, Puustusmaa M, Saar R, Sõber S, Møller P, Andreassen OA, Padrik P, Hovig E (2023)
    A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population
    Cancers (Basel), 15 (16)
    DOI 10.3390/cancers15164124, PubMed 37627152
  2. Anzar I, Malone B, Samarakoon P, Vardaxis I, Simovski B, Fontenelle H, Meza-Zepeda LA, Stratford R, Keung EZ, Burgess M, Tawbi HA, Myklebost O, Clancy T (2023)
    The interplay between neoantigens and immune cells in sarcomas treated with checkpoint inhibition
    Front Immunol, 14, 1226445
    DOI 10.3389/fimmu.2023.1226445, PubMed 37799721
  3. Arjona-Sanchez A, Martinez-López A, Moreno-Montilla MT, Mulsow J, Lozano-Lominchar P, Martínez-Torres B, Rau B, Canbay E, Sommariva A, Milione M, Deraco M, Sgarbura O, Torgunrud A, Kepenekian V, Carr NJ, Hoorens A, Delhorme JB, Wernert R, Goere D, Martin-Roman L, Cosyns S, Flatmark K, Davidson B, Khellaf L, Pereira-Perez F et al. (2023)
    External multicentre validation of pseudomyxoma peritonei PSOGI-Ki67 classification
    Eur J Surg Oncol, 49 (8), 1481-1488
    DOI 10.1016/j.ejso.2023.03.206, PubMed 36935222
  4. Ballinger ML, Pattnaik S, Mundra PA, Zaheed M, Rath E, Priestley P, Baber J, Ray-Coquard I, Isambert N, Causeret S, van der Graaf WTA, Puri A, Duffaud F, Le Cesne A, Seddon B, Chandrasekar C, Schiffman JD, Brohl AS, James PA, Kurtz JE, Penel N, Myklebost O, Meza-Zepeda LA, Pickett H, Kansara M et al. (2023)
    Heritable defects in telomere and mitotic function selectively predispose to sarcomas
    Science, 379 (6629), 253-260
    DOI 10.1126/science.abj4784, PubMed 36656928
  5. Billingham L, Brown L, Framke T, Greystoke A, Hovig E, Mathur S, Page P, Pean E, Barjesteh van Waalwijk van Doorn-Khosrovani S, Vonk R, Wissink S, Zander H, Plummer R (2023)
    Histology independent drug development - Is this the future for cancer drugs?
    Cancer Treat Rev, 123, 102674
    DOI 10.1016/j.ctrv.2023.102674, PubMed 38176220
  6. Bucher-Johannessen C, Birkeland EE, Vinberg E, Bemanian V, Hoff G, Berstad P, Rounge TB (2023)
    Long-term follow-up of colorectal cancer screening attendees identifies differences in Phascolarctobacterium spp. using 16S rRNA and metagenome sequencing
    Front Oncol, 13, 1183039
    DOI 10.3389/fonc.2023.1183039, PubMed 37182146
  7. Dominguez-Valentin M, Haupt S, Seppälä TT, Sampson JR, Sunde L, Bernstein I, Jenkins MA, Engel C, Aretz S, Nielsen M, Capella G, Balaguer F, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Della Valle A et al. (2023)
    Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database
    EClinicalMedicine, 58, 101909
    DOI 10.1016/j.eclinm.2023.101909, PubMed 37181409
  8. Doutel D, Davidson B, Nitschke Pettersen IK, Torgunrud A (2023)
    Molecular characteristics of low-grade serous carcinoma in effusions
    Cytopathology, 34 (2), 99-105
    DOI 10.1111/cyt.13207, PubMed 36609991
  9. Ellingsen EB, O'Day S, Mezheyeuski A, Gromadka A, Clancy T, Kristedja TS, Milhem M, Zakharia Y (2023)
    Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial
    Clin Cancer Res, 29 (16), 3026-3036
    DOI 10.1158/1078-0432.CCR-23-0416, PubMed 37378632
  10. Figlioli G, Billaud A, Wang Q, Bolla MK, Dennis J, Lush M, Kvist A, Adank MA, Ahearn TU, Antonenkova NN, Auvinen P, Behrens S, Bermisheva M, Bogdanova NV, Bojesen SE, Bonanni B, Brüning T, Camp NJ, Campbell A, Castelao JE, Cessna MH, Nbcs Collaborators, Czene K, Devilee P, Dörk T et al. (2023)
    Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases
    Cancers (Basel), 15 (13)
    DOI 10.3390/cancers15133313, PubMed 37444426
  11. Getu AA, Tigabu A, Zhou M, Lu J, Fodstad Ø, Tan M (2023)
    New frontiers in immune checkpoint B7-H3 (CD276) research and drug development
    Mol Cancer, 22 (1), 43
    DOI 10.1186/s12943-023-01751-9, PubMed 36859240
  12. Ghannoum S, Fantini D, Zahoor M, Reiterer V, Phuyal S, Leoncio Netto W, Sørensen Ø, Iyer A, Sengupta D, Prasmickaite L, Mælandsmo GM, Köhn-Luque A, Farhan H (2023)
    A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression
    PLoS Comput Biol, 19 (4), e1010995
    DOI 10.1371/journal.pcbi.1010995, PubMed 37068117
  13. Hanes R, Ayuda-Durán P, Rønneberg L, Nakken S, Hovig E, Zucknick M, Enserink JM (2023)
    screenwerk: a modular tool for the design and analysis of drug combination screens
    Bioinformatics, 39 (1)
    DOI 10.1093/bioinformatics/btac840, PubMed 36573326
  14. Haugen MH, von der Lippe Gythfeldt H, Egeland EV, Svartdal Normann L, Pandya AD, Vedin LL, Juell S, Tenstad E, Øy GF, Kristian A, Marangoni E, Sørlie T, Steffensen K, Maelandsmo GM, Engebraaten O (2023)
    Liver X receptors induce antiproliferative effects in basal-like breast cancer
    Mol Oncol, 17 (10), 2041-2055
    DOI 10.1002/1878-0261.13476, PubMed 37341140
  15. Hodan R, Rodgers-Fouche L, Chittenden A, Dominguez-Valentin M, Ferriss J, Gima L, Hamnvik OR, Idos GE, Kline K, Koeller DR, Long JM, McKenna D, Muller C, Thoman M, Wintner A, Bedrick BS, Collaborative Group of the Americas on Inherited Gastrointestinal Cancer (2023)
    Cancer surveillance for transgender and gender diverse patients with Lynch syndrome: a practice resource of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
    Fam Cancer, 22 (4), 437-448
    DOI 10.1007/s10689-023-00341-4, PubMed 37341816
  16. Holme B, Bjørnerud B, Pedersen NM, de la Ballina LR, Wesche J, Haugsten EM (2023)
    Automated tracking of cell migration in phase contrast images with CellTraxx
    Sci Rep, 13 (1), 22982
    DOI 10.1038/s41598-023-50227-9, PubMed 38151514
  17. Hyldbakk A, Fleten KG, Snipstad S, Åslund AKO, Davies CL, Flatmark K, Mørch Y (2023)
    Intraperitoneal administration of cabazitaxel-loaded nanoparticles in peritoneal metastasis models
    Nanomedicine, 48, 102656
    DOI 10.1016/j.nano.2023.102656, PubMed 36646195
  18. Ibrahim EIK, Ellingsen EB, Mangsbo SM, Friberg LE (2023)
    Bridging responses to a human telomerase reverse transcriptase-based peptide cancer vaccine candidate in a mechanism-based model
    Int Immunopharmacol, 126, 111225
    DOI 10.1016/j.intimp.2023.111225, PubMed 37988911
  19. Ito I, Yousef AM, Dickson PN, Naini ZA, White MG, Fleten KG, Flatmark K, Fournier KF, Fowlkes NW, Shen JP (2023)
    Antitumor activity of intraperitoneal paclitaxel in orthotopic patient-derived xenograft models of mucinous appendiceal adenocarcinoma
    bioRxiv
    DOI 10.1101/2023.02.01.526672, PubMed 36993681
  20. Kalyanasundaram S, Lefol Y, Gundersen S, Rognes T, Alsøe L, Nilsen HL, Hovig E, Sandve GK, Domanska D (2023)
    hGSuite HyperBrowser: A web-based toolkit for hierarchical metadata-informed analysis of genomic tracks
    PLoS One, 18 (7), e0286330
    DOI 10.1371/journal.pone.0286330, PubMed 37467208
  21. Knutsen E, Das Sajib S, Fiskaa T, Lorens J, Gudjonsson T, Mælandsmo GM, Johansen SD, Seternes OM, Perander M (2023)
    Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypes
    Front Oncol, 13, 1249895
    DOI 10.3389/fonc.2023.1249895, PubMed 38111531
  22. Lamsal A, Andersen SB, Johansson I, Vietri M, Bokil AA, Kurganovs NJ, Rylander F, Bjørkøy G, Pettersen K, Giambelluca MS (2023)
    Opposite and dynamic regulation of the interferon response in metastatic and non-metastatic breast cancer
    Cell Commun Signal, 21 (1), 50
    DOI 10.1186/s12964-023-01062-y, PubMed 36882786
  23. López JI, Hogan MF, Sutton B, Church SE, Angulo JC, Nunes-Xavier CE (2023)
    Distinct spatial landscapes in clear-cell renal cell carcinoma as revealed by whole transcriptome analysis
    Immunooncol Technol, 21, 100690
    DOI 10.1016/j.iotech.2023.100690, PubMed 38292905
  24. Mo T, Brandal SHB, Geier OM, Engebråten O, Nilsen LB, Kristensen VN, Hole KH, Hompland T, Fleischer T, Seierstad T (2023)
    MRI Assessment of Changes in Tumor Vascularization during Neoadjuvant Anti-Angiogenic Treatment in Locally Advanced Breast Cancer Patients
    Cancers (Basel), 15 (18)
    DOI 10.3390/cancers15184662, PubMed 37760629
  25. Mraz KA, Hodan R, Rodgers-Fouche L, Arora S, Balaguer F, Guillem JG, Jeter JM, Kanth P, Li D, Liska D, Melson J, Perez K, Ricker C, Shirts BH, Vilar E, Katona BW, Dominguez-Valentin M (2023)
    Current chemoprevention approaches in Lynch syndrome and Familial adenomatous polyposis: a global clinical practice survey
    Front Oncol, 13, 1141810
    DOI 10.3389/fonc.2023.1141810, PubMed 37293588
  26. Møller P, Seppälä TT, Ahadova A, Crosbie EJ, Holinski-Feder E, Scott R, Haupt S, Möslein G, Winship I, Broeke SWB, Kohut KE, Ryan N, Bauerfeind P, Thomas LE, Evans DG, Aretz S, Sijmons RH, Half E, Heinimann K, Horisberger K, Monahan K, Engel C, Cavestro GM, Fruscio R, Abu-Freha N et al. (2023)
    Dominantly inherited micro-satellite instable cancer - the four Lynch syndromes - an EHTG, PLSD position statement
    Hered Cancer Clin Pract, 21 (1), 19
    DOI 10.1186/s13053-023-00263-3, PubMed 37821984
  27. Nakken S, Gundersen S, Bernal FLM, Polychronopoulos D, Hovig E, Wesche J (2023)
    Comprehensive interrogation of gene lists from genome-scale cancer screens with oncoEnrichR
    Int J Cancer, 153 (10), 1819-1828
    DOI 10.1002/ijc.34666, PubMed 37551617
  28. Namløs HM, Khelik K, Nakken S, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2023)
    Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential
    Mol Oncol, 17 (11), 2432-2450
    DOI 10.1002/1878-0261.13514, PubMed 37622176
  29. Normann LS, Haugen MH, Hongisto V, Aure MR, Leivonen SK, Kristensen VN, Tahiri A, Engebraaten O, Sahlberg KK, Mælandsmo GM (2023)
    High-throughput screen in vitro identifies dasatinib as a candidate for combinatorial treatment with HER2-targeting drugs in breast cancer
    PLoS One, 18 (1), e0280507
    DOI 10.1371/journal.pone.0280507, PubMed 36706086
  30. Nunes-Xavier CE, Emaldi M, Mingo J, Øyjord T, Mælandsmo GM, Fodstad Ø, Errarte P, Larrinaga G, Llarena R, López JI, Pulido R (2023)
    The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma
    Sci Rep, 13 (1), 7339
    DOI 10.1038/s41598-023-34087-x, PubMed 37147361
  31. Nunes-Xavier CE, Emaldi M, Mingo J, Øyjord T, Mælandsmo GM, Fodstad Ø, Errarte P, Larrinaga G, Llarena R, López JI, Pulido R (2023)
    Author Correction: The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma
    Sci Rep, 13 (1), 9186
    DOI 10.1038/s41598-023-36328-5, PubMed 37280349
  32. Nygaard V, Ree AH, Dagenborg VJ, Børresen-Dale AL, Edwin B, Fretland ÅA, Grzyb K, Haugen MH, Mælandsmo GM, Flatmark K (2023)
    A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases
    Cancer Res Commun, 3 (2), 235-244
    DOI 10.1158/2767-9764.CRC-22-0295, PubMed 36968142
  33. Parry MA, Grist E, Mendes L, Dutey-Magni P, Sachdeva A, Brawley C, Murphy L, Proudfoot J, Lall S, Liu Y, Friedrich S, Ismail M, Hoyle A, Ali A, Haran A, Wingate A, Zakka L, Wetterskog D, Amos CL, Atako NB, Wang V, Rush HL, Jones RJ, Leung H, Cross WR et al. (2023)
    Clinical testing of transcriptome-wide expression profiles in high-risk localized and metastatic prostate cancer starting androgen deprivation therapy: an ancillary study of the STAMPEDE abiraterone Phase 3 trial
    Res Sq
    DOI 10.21203/rs.3.rs-2488586/v1, PubMed 36798177
  34. Patrick-Brown TDJH, Mohamed F, Thrower A, Torgunrud A, Cosyns S, Canbay E, Villeneuve L, Flatmark K, Brandl A (2023)
    Determining a minimum data set for reporting clinical and radiologic data for pseudomyxoma peritonei
    Pleura Peritoneum, 8 (1), 1-9
    DOI 10.1515/pp-2022-0200, PubMed 37020469
  35. Pettersen S, Øy GF, Egeland EV, Juell S, Engebråten O, Mælandsmo GM, Prasmickaite L (2023)
    Breast cancer patient-derived explant cultures recapitulate in vivo drug responses
    Front Oncol, 13, 1040665
    DOI 10.3389/fonc.2023.1040665, PubMed 36910663
  36. Połeć A, Ekstrøm PO, Fougner C, Sørlie T, Norum JH (2023)
    Rapid assessment of 3-dimensional intra-tumor heterogeneity through cycling temperature capillary electrophoresis
    BMC Res Notes, 16 (1), 167
    DOI 10.1186/s13104-023-06437-5, PubMed 37568187
  37. Pulido R, Nunes-Xavier CE (2023)
    Editorial: Cell and Developmental Signalling in Neuroblastoma
    Front Cell Dev Biol, 10, 1126352
    DOI 10.3389/fcell.2022.1126352, PubMed 36684434
  38. Rodgers-Fouche L, Arora S, Ricker C, Li D, Farooqi M, Balaguer F, Dominguez-Valentin M, Guillem JG, Kanth P, Liska D, Melson J, Mraz KA, Shirts BH, Vilar E, Katona BW, Hodan R (2023)
    Exploring Stakeholders' Perspectives on Implementing Universal Germline Testing for Colorectal Cancer: Findings From a Clinical Practice Survey
    JCO Precis Oncol, 7, e2300440
    DOI 10.1200/PO.23.00440, PubMed 37897815
  39. Rodríguez-Varela R, Moore KHS, Ebenesersdóttir SS, Kilinc GM, Kjellström A, Papmehl-Dufay L, Alfsdotter C, Berglund B, Alrawi L, Kashuba N, Sobrado V, Lagerholm VK, Gilbert E, Cavalleri GL, Hovig E, Kockum I, Olsson T, Alfredsson L, Hansen TF, Werge T, Munters AR, Bernhardsson C, Skar B, Christophersen A, Turner-Walker G et al. (2023)
    The genetic history of Scandinavia from the Roman Iron Age to the present
    Cell, 186 (1), 32-46.e19
    DOI 10.1016/j.cell.2022.11.024, PubMed 36608656
  40. Severson TM, Zhu Y, Prekovic S, Schuurman K, Nguyen HM, Brown LG, Hakkola S, Kim Y, Kneppers J, Linder S, Stelloo S, Lieftink C, van der Heijden M, Nykter M, van der Noort V, Sanders J, Morris B, Jenster G, van Leenders GJ, Pomerantz M, Freedman ML, Beijersbergen RL, Urbanucci A, Wessels L, Corey E et al. (2023)
    Enhancer profiling identifies epigenetic markers of endocrine resistance and reveals therapeutic options for metastatic castration-resistant prostate cancer patients
    medRxiv
    DOI 10.1101/2023.02.24.23286403, PubMed 36865297
  41. Solbakken AM, Flatmark K (2023)
    ASO Author Reflections: Navigation-Assisted Surgery for Locally Advanced and Recurrent Rectal Cancer: The NAVI-LARRC Trial
    Ann Surg Oncol, 30 (12), 7633-7634
    DOI 10.1245/s10434-023-14058-2, PubMed 37573284
  42. Solbakken AM, Sellevold S, Spasojevic M, Julsrud L, Emblemsvåg HL, Reims HM, Sørensen O, Thorgersen EB, Fauske L, Ågren JSM, Brennhovd B, Ryder T, Larsen SG, Flatmark K (2023)
    Navigation-Assisted Surgery for Locally Advanced Primary and Recurrent Rectal Cancer
    Ann Surg Oncol, 30 (12), 7602-7611
    DOI 10.1245/s10434-023-13964-9, PubMed 37481493
  43. Tamargo-Gómez I, Martínez-García GG, Suárez MF, Mayoral P, Bretones G, Astudillo A, Prieto-Lloret J, Sveen C, Fueyo A, Engedal N, López-Otín C, Mariño G (2023)
    Analysis of ATG4C function in vivo
    Autophagy, 19 (11), 2912-2933
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  44. Thorgersen EB, Solbakken AM, Strøm TK, Goscinski M, Spasojevic M, Larsen SG, Flatmark K (2023)
    Short-term results after robot-assisted surgery for primary rectal cancers requiring beyond total mesorectal excision in multiple compartments
    Scand J Surg, 113 (1), 3-12
    DOI 10.1177/14574969231200654, PubMed 37787437
  45. Torices L, Nunes-Xavier CE, López JI, Pulido R (2023)
    Novel anti-PTEN C2 domain monoclonal antibodies to analyse the expression and function of PTEN isoform variants
    PLoS One, 18 (8), e0289369
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Publications 2022

  1. Ahadova A, Witt J, Haupt S, Gallon R, Hüneburg R, Nattermann J, Ten Broeke S, Bohaumilitzky L, Hernandez-Sanchez A, Santibanez-Koref M, Jackson MS, Ahtiainen M, Pylvänäinen K, Andini K, Grolmusz VK, Möslein G, Dominguez-Valentin M, Møller P, Fürst D, Sijmons R, Borthwick GM, Burn J, Mecklin JP, Heuveline V, von Knebel Doeberitz M et al. (2022)
    Is HLA type a possible cancer risk modifier in Lynch syndrome?
    Int J Cancer, 152 (10), 2024-2031
    DOI 10.1002/ijc.34312, PubMed 36214792
  2. Alaña L, Nunes-Xavier CE, Zaldumbide L, Martin-Guerrero I, Mosteiro L, Alba-Pavón P, Villate O, García-Obregón S, González-García H, Herraiz R, Astigarraga I, Pulido R, García-Ariza M (2022)
    Identification and Functional Analysis of a Novel CTNNB1 Mutation in Pediatric Medulloblastoma
    Cancers (Basel), 14 (2)
    DOI 10.3390/cancers14020421, PubMed 35053583
  3. Alver TN, Heintz KM, Hovig E, Bøe SL (2022)
    Cooperative induction of receptor tyrosine kinases contributes to adaptive MAPK drug resistance in melanoma through the PI3K pathway
    Cancer Rep (Hoboken), 6 (2), e1736
    DOI 10.1002/cnr2.1736, PubMed 36251678
  4. Ambrosini M, Del Re M, Manca P, Hendifar A, Drilon A, Harada G, Ree AH, Klempner S, Mælandsmo GM, Flatmark K, Russnes HG, Cleary JM, Singh H, Sottotetti E, Martinetti A, Randon G, Sartore-Bianchi A, Capone I, Milione M, Di Bartolomeo M, Pietrantonio F (2022)
    ALK Inhibitors in Patients With ALK Fusion-Positive GI Cancers: An International Data Set and a Molecular Case Series
    JCO Precis Oncol, 6 (1), e2200015
    DOI 10.1200/PO.22.00015, PubMed 35476549
  5. Bjørklund SS, Aure MR, Häkkinen J, Vallon-Christersson J, Kumar S, Evensen KB, Fleischer T, Tost J, OSBREAC, Sahlberg KK, Mathelier A, Bhanot G, Ganesan S, Tekpli X, Kristensen VN (2022)
    Subtype and cell type specific expression of lncRNAs provide insight into breast cancer
    Commun Biol, 5 (1), 834
    DOI 10.1038/s42003-022-03559-7, PubMed 35982125
  6. Cao S, Wang JR, Ji S, Yang P, Dai Y, Guo S, Montierth MD, Shen JP, Zhao X, Chen J, Lee JJ, Guerrero PA, Spetsieris N, Engedal N, Taavitsainen S, Yu K, Livingstone J, Bhandari V, Hubert SM, Daw NC, Futreal PA, Efstathiou E, Lim B, Viale A, Zhang J et al. (2022)
    Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression
    Nat Biotechnol, 40 (11), 1624-1633
    DOI 10.1038/s41587-022-01342-x, PubMed 35697807
  7. Cavestro GM, Mannucci A, Balaguer F, Hampel H, Kupfer SS, Repici A, Sartore-Bianchi A, Seppälä TT, Valentini V, Boland CR, Brand RE, Buffart TE, Burke CA, Caccialanza R, Cannizzaro R, Cascinu S, Cercek A, Crosbie EJ, Danese S, Dekker E, Daca-Alvarez M, Deni F, Dominguez-Valentin M, Eng C, Goel A et al. (2022)
    Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines
    Clin Gastroenterol Hepatol, 21 (3), 581-603.e33
    DOI 10.1016/j.cgh.2022.12.006, PubMed 36549470
  8. Dominguez-Valentin M, Sampson JR, Seppälä TT, Møller P (2022)
    Response to Chambuso et al
    Genet Med, 24 (5), 1151
    DOI 10.1016/j.gim.2022.01.005, PubMed 35216900
  9. Ellingsen EB, Bounova G, Kerzeli I, Anzar I, Simnica D, Aamdal E, Guren T, Clancy T, Mezheyeuski A, Inderberg EM, Mangsbo SM, Binder M, Hovig E, Gaudernack G (2022)
    Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination
    J Transl Med, 20 (1), 419
    DOI 10.1186/s12967-022-03624-z, PubMed 36089578
  10. Ellingsen EB, Aamdal E, Guren T, Lilleby W, Brunsvig PF, Mangsbo SM, Aamdal S, Hovig E, Mensali N, Gaudernack G, Inderberg EM (2022)
    Durable and dynamic hTERT immune responses following vaccination with the long-peptide cancer vaccine UV1: long-term follow-up of three phase I clinical trials
    J Immunother Cancer, 10 (5)
    DOI 10.1136/jitc-2021-004345, PubMed 35613827
  11. Emaldi M, Nunes-Xavier CE (2022)
    B7-H4 Immune Checkpoint Protein Affects Viability and Targeted Therapy of Renal Cancer Cells
    Cells, 11 (9)
    DOI 10.3390/cells11091448, PubMed 35563753
  12. Engedal N, Proikas-Cezanne T, Albertini MC, Žerovnik E, Lane JD (2022)
    Transautophagy: Research and Translation of Autophagy Knowledge 2020
    Oxid Med Cell Longev, 2022, 9792132
    DOI 10.1155/2022/9792132, PubMed 35340207
  13. Engedal N, Sønstevold T, Beese CJ, Selladurai S, Melcher T, Simensen JE, Frankel LB, Urbanucci A, Torgersen ML (2022)
    Measuring Autophagic Cargo Flux with Keima-Based Probes
    Methods Mol Biol, 2445, 99-115
    DOI 10.1007/978-1-0716-2071-7_7, PubMed 34972988
  14. Fiorito E, Szybowska P, Haugsten EM, Kostas M, Øy GF, Wiedlocha A, Singh S, Nakken S, Mælandsmo GM, Fletcher JA, Meza-Zepeda LA, Wesche J (2022)
    Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
    Br J Cancer, 127 (11), 1939-1953
    DOI 10.1038/s41416-022-01973-6, PubMed 36097178
  15. Fleten KG, Hyldbakk A, Einen C, Benjakul S, Strand BL, Davies CL, Mørch Ý, Flatmark K (2022)
    Alginate Microsphere Encapsulation of Drug-Loaded Nanoparticles: A Novel Strategy for Intraperitoneal Drug Delivery
    Mar Drugs, 20 (12)
    DOI 10.3390/md20120744, PubMed 36547891
  16. Flobak Å, Skånland SS, Hovig E, Taskén K, Russnes HG (2022)
    Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
    Trends Pharmacol Sci, 43 (11), 973-985
    DOI 10.1016/j.tips.2022.08.009, PubMed 36163057
  17. Fromm B, Høye E, Domanska D, Zhong X, Aparicio-Puerta E, Ovchinnikov V, Umu SU, Chabot PJ, Kang W, Aslanzadeh M, Tarbier M, Mármol-Sánchez E, Urgese G, Johansen M, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2022)
    MirGeneDB 2.1: toward a complete sampling of all major animal phyla
    Nucleic Acids Res, 50 (D1), D204-D210
    DOI 10.1093/nar/gkab1101, PubMed 34850127
  18. Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2022)
    Corrigendum to "Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft", [Journal of Control Release, 293 (2019) 183-192]
    J Control Release, 349, 1
    DOI 10.1016/j.jconrel.2022.06.040, PubMed 35792388
  19. Georgiesh T, Aggerholm-Pedersen N, Schöffski P, Zhang Y, Napolitano A, Bovée JVMG, Hjelle Å, Tang G, Spalek M, Nannini M, Swanson D, Baad-Hansen T, Sciot R, Hesla AC, Huang P, Dorleijn D, Haugland HK, Lacambra M, Skoczylas J, Pantaleo MA, Haas RL, Meza-Zepeda LA, Haller F, Czarnecka AM, Loong H et al. (2022)
    Validation of a novel risk score to predict early and late recurrence in solitary fibrous tumour
    Br J Cancer, 127 (10), 1793-1798
    DOI 10.1038/s41416-022-01959-4, PubMed 36030294
  20. Giliberto M, Santana LM, Holien T, Misund K, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Coward E, Waage A, Taskén K, Skånland SS (2022)
    Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
    Front Oncol, 12, 1040730
    DOI 10.3389/fonc.2022.1040730, PubMed 36523963
  21. Gopalakrishnan S, Ebenesersdóttir SS, Lundstrøm IKC, Turner-Walker G, Moore KHS, Luisi P, Margaryan A, Martin MD, Ellegaard MR, Magnússon ÓÞ, Sigurðsson Á, Snorradóttir S, Magnúsdóttir DN, Laffoon JE, van Dorp L, Liu X, Moltke I, Ávila-Arcos MC, Schraiber JG, Rasmussen S, Juan D, Gelabert P, de-Dios T, Fotakis AK, Iraeta-Orbegozo M et al. (2022)
    The population genomic legacy of the second plague pandemic
    Curr Biol, 32 (21), 4743-4751.e6
    DOI 10.1016/j.cub.2022.09.023, PubMed 36182700
  22. Gorunova L, Boye K, Panagopoulos I, Berner JM, Bjerkehagen B, Hompland I, Lobmaier I, Hølmebakk T, Hveem TS, Heim S, Micci F (2022)
    Cytogenetic and molecular analyses of 291 gastrointestinal stromal tumors: site-specific cytogenetic evolution as evidence of pathogenetic heterogeneity
    Oncotarget, 13, 508-517
    DOI 10.18632/oncotarget.28209, PubMed 35284037
  23. Guldvik IJ, Braadland PR, Sivanesan S, Ramberg H, Kristensen G, Tennstedt P, Røder A, Schlomm T, Berge V, Eri LM, Lilleby W, Mills IG, Taskén KA (2022)
    Low Blood Levels of LRG1 Before Radical Prostatectomy Identify Patients with High Risk of Progression to Castration-resistant Prostate Cancer
    Eur Urol Open Sci, 45, 68-75
    DOI 10.1016/j.euros.2022.09.002, PubMed 36353660
  24. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
    Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
    J Transl Med, 20 (1), 225
    DOI 10.1186/s12967-022-03432-5, PubMed 35568909
  25. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
    Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
    J Transl Med, 20 (1), 317
    DOI 10.1186/s12967-022-03518-0, PubMed 35841045
  26. Hodan R, Rodgers-Fouche L, Arora S, Dominguez-Valentin M, Kanth P, Katona BW, Mraz KA, Roberts ME, Vilar E, Soto-Azghani CM, Brand RE, Esplin ED, Perez K (2022)
    Patterns of germline and somatic testing after universal tumor screening for Lynch syndrome: A clinical practice survey of active members of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
    J Genet Couns, 31 (4), 949-955
    DOI 10.1002/jgc4.1567, PubMed 35218578
  27. Høye E, Dagenborg VJ, Torgunrud A, Lund-Andersen C, Fretland ÅA, Lorenz S, Edwin B, Hovig E, Fromm B, Inderberg EM, Greiff V, Ree AH, Flatmark K (2022)
    T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases
    Gigascience, 12
    DOI 10.1093/gigascience/giad032, PubMed 37161965
  28. Høye E, Fromm B, Böttger PHM, Domanska D, Torgunrud A, Lund-Andersen C, Abrahamsen TW, Fretland ÅA, Dagenborg VJ, Lorenz S, Edwin B, Hovig E, Flatmark K (2022)
    A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer
    NAR Cancer, 4 (1), zcab051
    DOI 10.1093/narcan/zcab051, PubMed 35047825
  29. Li H, Engel C, Hoya M, Peterlongo P, Yannoukakos D, Livraghi L, Radice P, Thomassen M, Hansen TVO, Gerdes AM, Nielsen HR, Caputo SM, Zambelli A, Borg A, Solano A, Thomas A, Parsons MT, Antoniou AC, Leslie G, Yang X, Chenevix-Trench G, Caldes T, Kwong A, Pedersen IS, Lautrup CK et al. (2022)
    Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
    Genet Med, 24 (10), 2208
    DOI 10.1016/j.gim.2022.08.005, PubMed 36205748
  30. Meltzer S, Negård A, Bakke KM, Hamre HM, Kersten C, Hofsli E, Guren MG, Sorbye H, Flatmark K, Ree AH (2022)
    Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
    Br J Cancer, 127 (12), 2227-2233
    DOI 10.1038/s41416-022-02004-0, PubMed 36229579
  31. Metcalfe KA, Gronwald J, Tung NM, McCuaig JM, Eisen A, Elser C, Foulkes WD, Neuhausen SL, Senter L, Moller P, Bordeleau L, Fruscio R, Velsher L, Zakalik D, Olopade OI, Eng C, Pal T, Cullinane CA, Couch FJ, Kotsopoulos J, Sun P, Lubinski J, Narod SA (2022)
    The risks of cancer in older women with BRCA pathogenic variants: How far have we come?
    Cancer, 129 (6), 901-907
    DOI 10.1002/cncr.34615, PubMed 36571512
  32. Misund K, Hofste Op Bruinink D, Coward E, Hoogenboezem RM, Rustad EH, Sanders MA, Rye M, Sponaas AM, van der Holt B, Zweegman S, Hovig E, Meza-Zepeda LA, Sundan A, Myklebost O, Sonneveld P, Waage A (2022)
    Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence
    Leukemia, 36 (7), 1887-1897
    DOI 10.1038/s41375-022-01597-y, PubMed 35643867
  33. Mo T, Brandal SHB, Köhn-Luque A, Engebraaten O, Kristensen VN, Fleischer T, Hompland T, Seierstad T (2022)
    Quantification of Tumor Hypoxia through Unsupervised Modelling of Consumption and Supply Hypoxia MR Imaging in Breast Cancer
    Cancers (Basel), 14 (5)
    DOI 10.3390/cancers14051326, PubMed 35267636
  34. Møller P (2022)
    The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
    Hered Cancer Clin Pract, 20 (1), 37
    DOI 10.1186/s13053-022-00243-z, PubMed 36411472
  35. Møller P, Evans DG (2022)
    Inherited Cancer Genetic Epidemiology to Improve Precision Medicine
    J Clin Med, 11 (3)
    DOI 10.3390/jcm11030879, PubMed 35160330
  36. Møller P, Seppälä T, Dowty JG, Haupt S, Dominguez-Valentin M, Sunde L, Bernstein I, Engel C, Aretz S, Nielsen M, Capella G, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Valle AD, Heinimann K et al. (2022)
    Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
    Hered Cancer Clin Pract, 20 (1), 36
    DOI 10.1186/s13053-022-00241-1, PubMed 36182917
  37. Namløs HM, Skårn M, Ahmed D, Grad I, Andresen K, Kresse SH, Munthe E, Serra M, Scotlandi K, Llombart-Bosch A, Myklebost O, Lind GE, Meza-Zepeda LA (2022)
    miR-486-5p expression is regulated by DNA methylation in osteosarcoma
    BMC Genomics, 23 (1), 142
    DOI 10.1186/s12864-022-08346-6, PubMed 35172717
  38. Ng MYW, Charsou C, Lapao A, Singh S, Trachsel-Moncho L, Schultz SW, Nakken S, Munson MJ, Simonsen A (2022)
    The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
    Nat Commun, 13 (1), 6283
    DOI 10.1038/s41467-022-33933-2, PubMed 36270994
  39. Normann LS, Haugen MH, Aure MR, Kristensen VN, Mælandsmo GM, Sahlberg KK (2022)
    miR-101-5p Acts as a Tumor Suppressor in HER2-Positive Breast Cancer Cells and Improves Targeted Therapy
    Breast Cancer (Dove Med Press), 14, 25-39
    DOI 10.2147/BCTT.S338404, PubMed 35256859
  40. Nunes-Xavier CE, Emaldi M, Guldvik IJ, Ramberg H, Taskén KA, Mælandsmo GM, Fodstad Ø, Llarena R, Pulido R, López JI (2022)
    Correlation of expression of Major Vault Protein with androgen receptor and immune checkpoint protein B7-H3, and with poor prognosis in prostate cancer
    Pathol Res Pract, 241, 154243
    DOI 10.1016/j.prp.2022.154243, PubMed 36481650
  41. Nunes-Xavier CE, Mingo J, Emaldi M, Flem-Karlsen K, Mælandsmo GM, Fodstad Ø, Llarena R, López JI, Pulido R (2022)
    Heterogeneous Expression and Subcellular Localization of Pyruvate Dehydrogenase Complex in Prostate Cancer
    Front Oncol, 12, 873516
    DOI 10.3389/fonc.2022.873516, PubMed 35692804
  42. Nyakas M, Fleten KG, Haugen MH, Engedal N, Sveen C, Farstad IN, Flørenes VA, Prasmickaite L, Mælandsmo GM, Seip K (2022)
    AXL inhibition improves BRAF-targeted treatment in melanoma
    Sci Rep, 12 (1), 5076
    DOI 10.1038/s41598-022-09078-z, PubMed 35332208
  43. Pinto R, Hauge T, Jeanmougin M, Pharo HD, Kresse SH, Honne H, Winge SB, Five MB, Kumar T, Mala T, Hauge T, Johnson E, Lind GE (2022)
    Targeted genetic and epigenetic profiling of esophageal adenocarcinomas and non-dysplastic Barrett's esophagus
    Clin Epigenetics, 14 (1), 77
    DOI 10.1186/s13148-022-01287-7, PubMed 35701814
  44. Pulido R, Nunes-Xavier CE (2022)
    Hopes on immunotherapy targeting B7-H3 in neuroblastoma
    Transl Oncol, 27, 101580
    DOI 10.1016/j.tranon.2022.101580, PubMed 36327699
  45. Ree AH, Mælandsmo GM, Flatmark K, Russnes HG, Gómez Castañeda M, Aas E (2022)
    Cost-effectiveness of molecularly matched off-label therapies for end-stage cancer - the MetAction precision medicine study
    Acta Oncol, 61 (8), 955-962
    DOI 10.1080/0284186X.2022.2098053, PubMed 35943168
  46. Sivanesan S, Taskén KA, Grytli HH (2022)
    Association of β-Blocker Use at Time of Radical Prostatectomy With Rate of Treatment for Prostate Cancer Recurrence
    JAMA Netw Open, 5 (1), e2145230
    DOI 10.1001/jamanetworkopen.2021.45230, PubMed 35080602
  47. Sohlberg E, Pfefferle A, Heggernes Ask E, Tschan-Plessl A, Jacobs B, Netskar H, Lorenz S, Kanaya M, Kosugi-Kanaya M, Meinke S, Mörtberg A, Höglund P, Sundin M, Carlsson G, Palmblad J, Malmberg KJ (2022)
    Perturbed NK-cell homeostasis associated with disease severity in chronic neutropenia
    Blood, 139 (5), 704-716
    DOI 10.1182/blood.2021013233, PubMed 34699594
  48. Stacchiotti S, Dürr HR, Schaefer IM, Woertler K, Haas R, Trama A, Caraceni A, Bajpai J, Baldi GG, Bernthal N, Blay JY, Boye K, Broto JM, Chen WT, Dei Tos PA, Desai J, Emhofer S, Eriksson M, Gronchi A, Gelderblom H, Hardes J, Hartmann W, Healey J, Italiano A, Jones RL et al. (2022)
    Best clinical management of tenosynovial giant cell tumour (TGCT): A consensus paper from the community of experts
    Cancer Treat Rev, 112, 102491
    DOI 10.1016/j.ctrv.2022.102491, PubMed 36502615
  49. Søreng K, Pankiv S, Bergsmark C, Haugsten EM, Dahl AK, de la Ballina LR, Yamamoto A, Lystad AH, Simonsen A (2022)
    ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration
    J Cell Sci, 135 (4)
    DOI 10.1242/jcs.259138, PubMed 35099014
  50. Taskén K, Russnes HEG, Aas E, Bjørge L, Blix ES, CONNECT Public–Private Partnership Consortium, Enerly E, Fagereng GL, Flobak Å, Gilje B, Gjertsen BT, Guren TK, Heix J, Hovig E, Hovland R, InPreD-Norway and National Molecular Tumor Board Consortium, IMPRESS-Norway Consortium, Lønning PE, Meza-Zepeda LA, Mæhle PM, Nilsen HL, Thoresen SØ, Widerberg K, Smeland S, Helland Å (2022)
    A national precision cancer medicine implementation initiative for Norway
    Nat Med, 28 (5), 885-887
    DOI 10.1038/s41591-022-01777-4, PubMed 35513529
  51. Tellez-Gabriel M, Tekpli X, Reine TM, Hegge B, Nielsen SR, Chen M, Moi L, Normann LS, Busund LR, Calin GA, Mælandsmo GM, Perander M, Theocharis AD, Kolset SO, Knutsen E (2022)
    Serglycin Is Involved in TGF-β Induced Epithelial-Mesenchymal Transition and Is Highly Expressed by Immune Cells in Breast Cancer Tissue
    Front Oncol, 12, 868868
    DOI 10.3389/fonc.2022.868868, PubMed 35494005
  52. Thomassen M, Mesman RLS, Hansen TVO, Menendez M, Rossing M, Esteban-Sánchez A, Tudini E, Törngren T, Parsons MT, Pedersen IS, Teo SH, Kruse TA, Møller P, Borg Å, Jensen UB, Christensen LL, Singer CF, Muhr D, Santamarina M, Brandao R, Andresen BS, Feng BJ, Canson D, Richardson ME, Karam R et al. (2022)
    Clinical, splicing, and functional analysis to classify BRCA2 exon 3 variants: Application of a points-based ACMG/AMP approach
    Hum Mutat, 43 (12), 1921-1944
    DOI 10.1002/humu.24449, PubMed 35979650
  53. Torices L, Mingo J, Rodríguez-Escudero I, Fernández-Acero T, Luna S, Nunes-Xavier CE, López JI, Mercadillo F, Currás M, Urioste M, Molina M, Cid VJ, Pulido R (2022)
    Functional analysis of PTEN variants of unknown significance from PHTS patients unveils complex patterns of PTEN biological activity in disease
    Eur J Hum Genet, 31 (5), 568-577
    DOI 10.1038/s41431-022-01265-w, PubMed 36543932
  54. Vaccaro CA, Soarez J, Dominguez-Valentin M, Pavicic WH (2022)
    Editorial: Advances in genetics and molecular diagnosis in colorectal, stomach, and pancreatic cancer
    Front Oncol, 12, 1104671
    DOI 10.3389/fonc.2022.1104671, PubMed 36601476
  55. Venizelos A, Engebrethsen C, Deng W, Geisler J, Geisler S, Iversen GT, Aas T, Aase HS, Seyedzadeh M, Steinskog ES, Myklebost O, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Lønning PE, Knappskog S, Eikesdal HP (2022)
    Clonal evolution in primary breast cancers under sequential epirubicin and docetaxel monotherapy
    Genome Med, 14 (1), 86
    DOI 10.1186/s13073-022-01090-2, PubMed 35948919
  56. Xia YY, Gronwald J, Karlan B, Lubinski J, McCuaig JM, Brooks J, Moller P, Eisen A, Sun S, Senter L, Bordeleau L, Neuhausen SL, Singer CF, Tung N, Foulkes WD, Sun P, Narod SA, Kotsopoulos J, Hereditary Ovarian Cancer Clinical Study Group (2022)
    Contraceptive use and the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation
    Gynecol Oncol, 164 (3), 514-521
    DOI 10.1016/j.ygyno.2022.01.014, PubMed 35063280
  57. Zavaleta E, Solis N, Palacios MI, Zevallos-Escobar LE, Corales EV, Bazo-Alvarez JC, Dominguez-Barrera C, Campos A, Wernhoff P, Ekstrøm PO, Møller P, Visnovska T, Hovig E, Balazar-Palacios J, Alvarez-Valenzuela K, Nakken S, Dominguez-Valentin M (2022)
    Genetic Characterization in High-Risk Individuals from a Low-Resource City of Peru
    Cancers (Basel), 14 (22)
    DOI 10.3390/cancers14225603, PubMed 36428697

Publications 2021

  1. Andersson Y, Fleten KG, Abrahamsen TW, Reed W, Davidson B, Flatmark K (2021)
    Anti-Angiogenic Treatment in Pseudomyxoma Peritonei-Still a Strong Preclinical Rationale
    Cancers (Basel), 13 (11)
    DOI 10.3390/cancers13112819, PubMed 34198773
  2. Barkovskaya A, Goodwin CM, Seip K, Hilmarsdottir B, Pettersen S, Stalnecker C, Engebraaten O, Briem E, Der CJ, Moestue SA, Gudjonsson T, Maelandsmo GM, Prasmickaite L (2021)
    Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen
    Mol Oncol, 15 (8), 2026-2045
    DOI 10.1002/1878-0261.12951, PubMed 33759347
  3. Baxter JS, Johnson N, Tomczyk K, Gillespie A, Maguire S, Brough R, Fachal L, Michailidou K, Bolla MK, Wang Q, Dennis J, Ahearn TU, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Augustinsson A, Becher H, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bogdanova NV, Bojesen SE et al. (2021)
    Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element
    Am J Hum Genet, 108 (7), 1190-1203
    DOI 10.1016/j.ajhg.2021.05.013, PubMed 34146516
  4. Boye K, Longhi A, Guren T, Lorenz S, Næss S, Pierini M, Taksdal I, Lobmaier I, Cesari M, Paioli A, Løndalen AM, Setola E, Hompland I, Meza-Zepeda LA, Sundby Hall K, Palmerini E (2021)
    Pembrolizumab in advanced osteosarcoma: results of a single-arm, open-label, phase 2 trial
    Cancer Immunol Immunother, 70 (9), 2617-2624
    DOI 10.1007/s00262-021-02876-w, PubMed 33580363
  5. Cangiano M, Grudniewska M, Salji MJ, Nykter M, Jenster G, Urbanucci A, Granchi Z, Janssen B, Hamilton G, Leung HY, Beumer IJ (2021)
    Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the JMJD6 Regulon in Clinical Prostate Cancer
    Cancers (Basel), 13 (9)
    DOI 10.3390/cancers13092094, PubMed 33925994
  6. Christensen SB, Simonsen HT, Engedal N, Nissen P, Møller JV, Denmeade SR, Isaacs JT (2021)
    From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development
    Prog Chem Org Nat Prod, 115, 59-114
    DOI 10.1007/978-3-030-64853-4_2, PubMed 33797641
  7. Dagenborg VJ, Marshall SE, Grzyb K, Fretland ÅA, Lund-Iversen M, Mælandsmo GM, Ree AH, Edwin B, Yaqub S, Flatmark K (2021)
    Low Concordance Between T-Cell Densities in Matched Primary Tumors and Liver Metastases in Microsatellite Stable Colorectal Cancer
    Front Oncol, 11, 671629
    DOI 10.3389/fonc.2021.671629, PubMed 34178659
  8. Dominguez-Valentin M, Plazzer JP, Sampson JR, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Macrae F, Winship IM, Thomas H, Evans DG, Burn J, Greenblatt M, de Vos Tot Nederveen Cappel WH, Sijmons RH, Nielsen M, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Lindblom A, Valle AD et al. (2021)
    No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study
    J Clin Med, 10 (13)
    DOI 10.3390/jcm10132856, PubMed 34203177
  9. Ellingsen EB, Mangsbo SM, Hovig E, Gaudernack G (2021)
    Telomerase as a Target for Therapeutic Cancer Vaccines and Considerations for Optimizing Their Clinical Potential
    Front Immunol, 12, 682492
    DOI 10.3389/fimmu.2021.682492, PubMed 34290704
  10. Engebraaten O, Yau C, Berg K, Borgen E, Garred Ø, Berstad MEB, Fremstedal ASV, DeMichele A, Veer LV', Esserman L, Weyergang A (2021)
    RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer
    Nat Commun, 12 (1), 6427
    DOI 10.1038/s41467-021-26018-z, PubMed 34741021
  11. Erdélyi K, Ditrói T, Johansson HJ, Czikora Á, Balog N, Silwal-Pandit L, Ida T, Olasz J, Hajdú D, Mátrai Z, Csuka O, Uchida K, Tóvári J, Engebraten O, Akaike T, Børresen Dale AL, Kásler M, Lehtiö J, Nagy P (2021)
    Reprogrammed transsulfuration promotes basal-like breast tumor progression via realigning cellular cysteine persulfidation
    Proc Natl Acad Sci U S A, 118 (45)
    DOI 10.1073/pnas.2100050118, PubMed 34737229
  12. Flatmark K, Torgunrud A, Fleten KG, Davidson B, Juul HV, Mensali N, Lund-Andersen C, Inderberg EM (2021)
    Peptide vaccine targeting mutated GNAS: a potential novel treatment for pseudomyxoma peritonei
    J Immunother Cancer, 9 (10)
    DOI 10.1136/jitc-2021-003109, PubMed 34711663
  13. Fleten KG, Eksteen JJ, Mauseth B, Camilio KA, Vasskog T, Sveinbjørnsson B, Rekdal Ø, Mælandsmo GM, Flatmark K (2021)
    Oncolytic peptides DTT-205 and DTT-304 induce complete regression and protective immune response in experimental murine colorectal cancer
    Sci Rep, 11 (1), 6731
    DOI 10.1038/s41598-021-86239-6, PubMed 33762676
  14. Georgiesh T, Namløs HM, Sharma N, Lorenz S, Myklebost O, Bjerkehagen B, Meza-Zepeda LA, Boye K (2021)
    Clinical and molecular implications of NAB2-STAT6 fusion variants in solitary fibrous tumour
    Pathology, 53 (6), 713-719
    DOI 10.1016/j.pathol.2020.11.010, PubMed 33745702
  15. Grad I, Hanes R, Ayuda-Durán P, Kuijjer ML, Enserink JM, Meza-Zepeda LA, Myklebost O (2021)
    Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening
    PLoS One, 16 (3), e0248140
    DOI 10.1371/journal.pone.0248140, PubMed 33690666
  16. Guerriero I, Ramberg H, Sagini K, Ramirez-Garrastacho M, Taskén KA, Llorente A (2021)
    Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells
    PLoS One, 16 (6), e0253828
    DOI 10.1371/journal.pone.0253828, PubMed 34191854
  17. Guldvik IJ, Ekseth L, Kishan AU, Stensvold A, Inderberg EM, Lilleby W (2021)
    Circulating Tumor Cell Persistence Associates with Long-Term Clinical Outcome to a Therapeutic Cancer Vaccine in Prostate Cancer
    J Pers Med, 11 (7)
    DOI 10.3390/jpm11070605, PubMed 34206815
  18. Gundersen S, Boddu S, Capella-Gutierrez S, Drabløs F, Fernández JM, Kompova R, Taylor K, Titov D, Zerbino D, Hovig E (2021)
    Recommendations for the FAIRification of genomic track metadata
    F1000Res, 10
    DOI 10.12688/f1000research.28449.1, PubMed 34249331
  19. Haugen MH, Lingjærde OC, Hedenfalk I, Garred Ø, Borgen E, Loman N, Hatschek T, Børresen-Dale AL, Naume B, Mills GB, Mælandsmo GM, Engebraaten O (2021)
    Protein Signature Predicts Response to Neoadjuvant Treatment With Chemotherapy and Bevacizumab in HER2-Negative Breast Cancers
    JCO Precis Oncol, 5
    DOI 10.1200/PO.20.00086, PubMed 34036235
  20. Hovda T, Hoff SR, Larsen M, Romundstad L, Sahlberg KK, Hofvind S (2021)
    True and Missed Interval Cancer in Organized Mammographic Screening: A Retrospective Review Study of Diagnostic and Prior Screening Mammograms
    Acad Radiol, 29 Suppl 1, S180-S191
    DOI 10.1016/j.acra.2021.03.022, PubMed 33926794
  21. Hølmebakk T, Boye K (2021)
    ASO Author Reflections: How to Identify Patients at Genuinely High Risk of Recurrence from Localized Gastrointestinal Stromal Tumor of the Stomach?
    Ann Surg Oncol, 28 (11), 6846-6847
    DOI 10.1245/s10434-021-09608-5, PubMed 33687615
  22. Hølmebakk T, Boye K (2021)
    Correction to: ASO Author Reflections: How to Identify Patients at Genuinely High Risk of Recurrence from Localized Gastrointestinal Stromal Tumor of the Stomach?
    Ann Surg Oncol, 28 (Suppl 3), 873
    DOI 10.1245/s10434-021-09939-3, PubMed 33829360
  23. Hølmebakk T, Wiedswang AM, Meza-Zepeda LA, Hompland I, Lobmaier IVK, Berner JM, Stoldt S, Boye K (2021)
    Integrating Anatomical, Molecular and Clinical Risk Factors in Gastrointestinal Stromal Tumor of the Stomach
    Ann Surg Oncol, 28 (11), 6837-6845
    DOI 10.1245/s10434-021-09605-8, PubMed 33651216
  24. Haakensen VD, Nowak AK, Ellingsen EB, Farooqi SJ, Bjaanæs MM, Horndalsveen H, Mcculloch T, Grundberg O, Cedres SM, Helland Å (2021)
    NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma
    J Transl Med, 19 (1), 232
    DOI 10.1186/s12967-021-02905-3, PubMed 34059094
  25. Kanduri C, Sandve GK, Hovig E, De S, Layer RM (2021)
    Editorial: Genomic Colocalization and Enrichment Analyses
    Front Genet, 11, 617876
    DOI 10.3389/fgene.2020.617876, PubMed 33574832
  26. Kang W, Fromm B, Houben AJ, Høye E, Bezdan D, Arnan C, Thrane K, Asp M, Johnson R, Biryukova I, Friedländer MR (2021)
    MapToCleave: High-throughput profiling of microRNA biogenesis in living cells
    Cell Rep, 37 (7), 110015
    DOI 10.1016/j.celrep.2021.110015, PubMed 34788611
  27. Karvelsson ST, Sigurdsson A, Seip K, Grinde MT, Wang Q, Johannsson F, Mælandsmo GM, Moestue SA, Rolfsson O, Halldorsson S (2021)
    EMT-Derived Alterations in Glutamine Metabolism Sensitize Mesenchymal Breast Cells to mTOR Inhibition
    Mol Cancer Res, 19 (9), 1546-1558
    DOI 10.1158/1541-7786.MCR-20-0962, PubMed 34088869
  28. Karvelsson ST, Wang Q, Hilmarsdottir B, Sigurdsson A, Moestue SA, Mælandsmo GM, Halldorsson S, Gudmundsson S, Rolfsson O (2021)
    Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer
    NPJ Syst Biol Appl, 7 (1), 36
    DOI 10.1038/s41540-021-00195-5, PubMed 34535676
  29. Kim SJ, Lubinski J, Huzarski T, Møller P, Armel S, Karlan BY, Senter L, Eisen A, Foulkes WD, Singer CF, Tung N, Bordeleau L, Neuhausen SL, Olopade OI, Eng C, Weitzel JN, Fruscio R, Narod SA, Kotsopoulos J, Hereditary Ovarian Cancer Clinical Study Group (2021)
    Weight Gain and the Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers
    Cancer Epidemiol Biomarkers Prev, 30 (11), 2038-2043
    DOI 10.1158/1055-9965.EPI-21-0296, PubMed 34426412
  30. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
    Autophagy, 17 (1), 1-382
    DOI 10.1080/15548627.2020.1797280, PubMed 33634751
  31. Krzyscik MA, Zakrzewska M, Sørensen V, Øy GF, Brunheim S, Haugsten EM, Mælandsmo GM, Wiedlocha A, Otlewski J (2021)
    Fibroblast Growth Factor 2 Conjugated with Monomethyl Auristatin E Inhibits Tumor Growth in a Mouse Model
    Biomacromolecules, 22 (10), 4169-4180
    DOI 10.1021/acs.biomac.1c00662, PubMed 34542998
  32. Kukkonen K, Taavitsainen S, Huhtala L, Uusi-Makela J, Granberg KJ, Nykter M, Urbanucci A (2021)
    Chromatin and Epigenetic Dysregulation of Prostate Cancer Development, Progression, and Therapeutic Response
    Cancers (Basel), 13 (13)
    DOI 10.3390/cancers13133325, PubMed 34283056
  33. Kværner AS, Birkeland E, Bucher-Johannessen C, Vinberg E, Nordby JI, Kangas H, Bemanian V, Ellonen P, Botteri E, Natvig E, Rognes T, Hovig E, Lyle R, Ambur OH, de Vos WM, Bultman S, Hjartåker A, Landberg R, Song M, Blix HS, Ursin G, Randel KR, de Lange T, Hoff G, Holme Ø et al. (2021)
    The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants
    BMC Cancer, 21 (1), 930
    DOI 10.1186/s12885-021-08640-8, PubMed 34407780
  34. Larrinaga G, Calvete-Candenas J, Solano-Iturri JD, Martín AM, Pueyo A, Nunes-Xavier CE, Pulido R, Dorado JF, López JI, Angulo JC (2021)
    (Pro)renin Receptor Is a Novel Independent Prognostic Marker in Invasive Urothelial Carcinoma of the Bladder
    Cancers (Basel), 13 (22)
    DOI 10.3390/cancers13225642, PubMed 34830803
  35. Larsen SG, Goscinski MA, Dueland S, Steigen SE, Hofsli E, Torgunrud A, Lund-Iversen M, Dagenborg VJ, Flatmark K, Sorbye H (2021)
    Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients
    Br J Cancer, 126 (5), 726-735
    DOI 10.1038/s41416-021-01620-6, PubMed 34887523
  36. Lesueur F, Easton DF, Renault AL, Tavtigian SV, Bernstein JL, Kote-Jarai Z, Eeles RA, Plaseska-Karanfia D, Feliubadaló L, Spanish ATM working group, Arun B, Herold N, Versmold B, Schmutzler RK, GC-HBOC, Nguyen-Dumont T, Southey MC, Dorling L, Dunning AM, Ghiorzo P, Dalmasso BS, Cavaciuti E, Le Gal D, Roberts NJ, Dominguez-Valentin M et al. (2021)
    First international workshop of the ATM and cancer risk group (4-5 December 2019)
    Fam Cancer, 21 (2), 211-227
    DOI 10.1007/s10689-021-00248-y, PubMed 34125377
  37. Li H, Engel C, de la Hoya M, Peterlongo P, Yannoukakos D, Livraghi L, Radice P, Thomassen M, Hansen TVO, Gerdes AM, Nielsen HR, Caputo SM, Zambelli A, Borg A, Solano A, Thomas A, Parsons MT, Antoniou AC, Leslie G, Yang X, Chenevix-Trench G, Caldes T, Kwong A, Pedersen IS, Lautrup CK et al. (2021)
    Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
    Genet Med, 24 (1), 119-129
    DOI 10.1016/j.gim.2021.08.016, PubMed 34906479
  38. Luna S, Torices L, Mingo J, Amo L, Rodríguez-Escudero I, Ruiz-Ibarlucea P, Erramuzpe A, Cortés JM, Tejada MI, Molina M, Nunes-Xavier CE, López JI, Cid VJ, Pulido R (2021)
    A global analysis of the reconstitution of PTEN function by translational readthrough of PTEN pathogenic premature termination codons
    Hum Mutat, 42 (5), 551-566
    DOI 10.1002/humu.24186, PubMed 33600059
  39. Lund-Andersen C, Torgunrud A, Fleten KG, Flatmark K (2021)
    Omics analyses in peritoneal metastasis-utility in the management of peritoneal metastases from colorectal cancer and pseudomyxoma peritonei: a narrative review
    J Gastrointest Oncol, 12 (Suppl 1), S191-S203
    DOI 10.21037/jgo-20-136, PubMed 33968437
  40. Mariathasan AB, Boye K, Dueland S, Flatmark K, Larsen SG (2021)
    Metastases in locally advanced rectal cancer undergoing curatively intended treatment
    Eur J Surg Oncol, 47 (9), 2377-2383
    DOI 10.1016/j.ejso.2021.04.023, PubMed 34049768
  41. Mattingsdal M, Ebenesersdóttir SS, Moore KHS, Andreassen OA, Hansen TF, Werge T, Kockum I, Olsson T, Alfredsson L, Helgason A, Stefánsson K, Hovig E (2021)
    The genetic structure of Norway
    Eur J Hum Genet, 29 (11), 1710-1718
    DOI 10.1038/s41431-021-00899-6, PubMed 34002043
  42. Meltzer S, Torgunrud A, Abrahamsson H, Solbakken AM, Flatmark K, Dueland S, Bakke KM, Bousquet PA, Negård A, Johansen C, Lyckander LG, Larsen FO, Schou JV, Redalen KR, Ree AH (2021)
    The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer
    Br J Cancer, 125 (2), 240-246
    DOI 10.1038/s41416-021-01377-y, PubMed 33837301
  43. Moghaddam S, Jalali A, O'Neill A, Murphy L, Gorman L, Reilly AM, Heffernan Á, Lynch T, Power R, O'Malley KJ, Taskèn KA, Berge V, Solhaug VA, Klocker H, Murphy TB, Watson RW (2021)
    Integrating Serum Biomarkers into Prediction Models for Biochemical Recurrence Following Radical Prostatectomy
    Cancers (Basel), 13 (16)
    DOI 10.3390/cancers13164162, PubMed 34439316
  44. Moller P, Sampson JR, Dominguez-Valentin M, Seppala TT (2021)
    Towards evidence-based personalised precision medicine for Lynch syndrome
    Lancet Oncol., 22 (9), E383
  45. Morra A, Escala-Garcia M, Beesley J, Keeman R, Canisius S, Ahearn TU, Andrulis IL, Anton-Culver H, Arndt V, Auer PL, Augustinsson A, Beane Freeman LE, Becher H, Beckmann MW, Behrens S, Bojesen SE, Bolla MK, Brenner H, Brüning T, Buys SS, Caan B, Campa D, Canzian F, Castelao JE, Chang-Claude J et al. (2021)
    Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment
    Breast Cancer Res, 23 (1), 86
    DOI 10.1186/s13058-021-01450-7, PubMed 34407845
  46. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A (2021)
    GAK and PRKCD are positive regulators of PRKN-independent mitophagy
    Nat Commun, 12 (1), 6101
    DOI 10.1038/s41467-021-26331-7, PubMed 34671015
  47. Møller P, Sampson J, Dominguez-Valentin M, Burn J, Sunde L, Möslein G, Mecklin JP, Seppälä T (2021)
    Correction to: Letter to the Editor-Recent advances in Lynch syndrome
    Fam Cancer, 20 (2), 119
    DOI 10.1007/s10689-021-00246-0, PubMed 33792829
  48. Møller P, Sampson JR, Dominguez-Valentin M, Seppälä TT (2021)
    Towards evidence-based personalised precision medicine for Lynch syndrome
    Lancet Oncol, 22 (9), e383
    DOI 10.1016/S1470-2045(21)00400-9, PubMed 34478667
  49. Nakken S, Lilleby W, Switlyk MD, Knudsen KE, Lilleby O, Zhao S, Kaveh F, Ekstrøm PO, Urbanucci A, Hovig E (2021)
    The Quandary of DNA-Based Treatment Assessment in De Novo Metastatic Prostate Cancer in the Era of Precision Oncology
    J Pers Med, 11 (5)
    DOI 10.3390/jpm11050330, PubMed 33922147
  50. Nakken S, Saveliev V, Hofmann O, Møller P, Myklebost O, Hovig E (2021)
    Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer
    Int J Cancer, 149 (11), 1955-1960
    DOI 10.1002/ijc.33749, PubMed 34310709
  51. Normann LS, Aure MR, Leivonen SK, Haugen MH, Hongisto V, Kristensen VN, Mælandsmo GM, Sahlberg KK (2021)
    MicroRNA in combination with HER2-targeting drugs reduces breast cancer cell viability in vitro
    Sci Rep, 11 (1), 10893
    DOI 10.1038/s41598-021-90385-2, PubMed 34035375
  52. Nunes-Xavier CE, Kildal W, Kleppe A, Danielsen HE, Waehre H, Llarena R, Maelandsmo GM, Fodstad Ø, Pulido R, López JI (2021)
    Immune checkpoint B7-H3 protein expression is associated with poor outcome and androgen receptor status in prostate cancer
    Prostate, 81 (12), 838-848
    DOI 10.1002/pros.24180, PubMed 34125445
  53. Nunes-Xavier CE, Zaldumbide L, Mosteiro L, López-Almaraz R, García de Andoin N, Aguirre P, Emaldi M, Torices L, López JI, Pulido R (2021)
    Protein Tyrosine Phosphatases in Neuroblastoma: Emerging Roles as Biomarkers and Therapeutic Targets
    Front Cell Dev Biol, 9, 811297
    DOI 10.3389/fcell.2021.811297, PubMed 34957126
  54. Oksvold MP, Berglund UW, Gad H, Bai B, Stokke T, Rein ID, Pham T, Sanjiv K, Øy GF, Norum JH, Smeland EB, Myklebust JH, Helleday T, Våtsveen TK (2021)
    Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma
    Sci Rep, 11 (1), 6317
    DOI 10.1038/s41598-021-85613-8, PubMed 33737576
  55. Pandya AD, Iversen TG, Moestue S, Grinde MT, Mørch Ý, Snipstad S, Åslund AKO, Øy GF, Kildal W, Engebråten O, Sandvig K, Skotland T, Mælandsmo GM (2021)
    Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
    Nanomaterials (Basel), 11 (5)
    DOI 10.3390/nano11051140, PubMed 33924869
  56. Park J, Choi JY, Choi J, Chung S, Song N, Park SK, Han W, Noh DY, Ahn SH, Lee JW, Kim MK, Jee SH, Wen W, Bolla MK, Wang Q, Dennis J, Michailidou K, Shah M, Conroy DM, Harrington PA, Mayes R, Czene K, Hall P, Teras LR, Patel AV et al. (2021)
    Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?
    Cancers (Basel), 13 (10)
    DOI 10.3390/cancers13102370, PubMed 34069208
  57. Pavlović M, Scheffer L, Motwani K, Kanduri C, Kompova R, Vazov N, Waagan K, Bernal FLM, Costa AA, Corrie B, Akbar R, Al Hajj GS, Balaban G, Brusko TM, Chernigovskaya M, Christley S, Cowell LG, Frank R, Grytten I, Gundersen S, Haff IH, Hovig E, Hsieh PH, Klambauer G, Kuijjer ML et al. (2021)
    The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires
    Nat Mach Intell, 3 (11), 936-944
    DOI 10.1038/s42256-021-00413-z, PubMed 37396030
  58. Peneder P, Stütz AM, Surdez D, Krumbholz M, Semper S, Chicard M, Sheffield NC, Pierron G, Lapouble E, Tötzl M, Ergüner B, Barreca D, Rendeiro AF, Agaimy A, Boztug H, Engstler G, Dworzak M, Bernkopf M, Taschner-Mandl S, Ambros IM, Myklebost O, Marec-Bérard P, Burchill SA, Brennan B, Strauss SJ et al. (2021)
    Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden
    Nat Commun, 12 (1), 3230
    DOI 10.1038/s41467-021-23445-w, PubMed 34050156
  59. Ramberg H, Richardsen E, de Souza GA, Rakaee M, Stensland ME, Braadland PR, Nygård S, Ögren O, Guldvik IJ, Berge V, Svindland A, Taskén KA, Andersen S (2021)
    Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
    Carcinogenesis, 42 (5), 685-693
    DOI 10.1093/carcin/bgab015, PubMed 33609362
  60. Ramirez-Garrastacho M, Bajo-Santos C, Line A, Martens-Uzunova ES, de la Fuente JM, Moros M, Soekmadji C, Tasken KA, Llorente A (2021)
    Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: a decade of research
    Br J Cancer, 126 (3), 331-350
    DOI 10.1038/s41416-021-01610-8, PubMed 34811504
  61. Schläfli AM, Tokarchuk I, Parejo S, Jutzi S, Berezowska S, Engedal N, Tschan MP (2021)
    ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells
    Sci Rep, 11 (1), 9011
    DOI 10.1038/s41598-021-87966-6, PubMed 33907223
  62. Seppälä TT, Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2021)
    Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
    Eur J Cancer, 148, 124-133
    DOI 10.1016/j.ejca.2021.02.022, PubMed 33743481
  63. Seppälä TT, Latchford A, Negoi I, Sampaio Soares A, Jimenez-Rodriguez R, Sánchez-Guillén L, Evans DG, Ryan N, Crosbie EJ, Dominguez-Valentin M, Burn J, Kloor M, Knebel Doeberitz MV, Duijnhoven FJBV, Quirke P, Sampson JR, Møller P, Möslein G, European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP) (2021)
    European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender
    Br J Surg, 108 (5), 484-498
    DOI 10.1002/bjs.11902, PubMed 34043773
  64. Solis N, Zavaleta E, Wernhoff P, Dominguez-Barrera C, Dominguez-Valentin M (2021)
    Challenges to Bringing Personalized Medicine to a Low-Resource Setting in Peru
    Int J Environ Res Public Health, 18 (4)
    DOI 10.3390/ijerph18041470, PubMed 33557277
  65. Stabell M, Sæther T, Røhr ÅK, Gabrielsen OS, Myklebost O (2021)
    Methylation-dependent SUMOylation of the architectural transcription factor HMGA2
    Biochem Biophys Res Commun, 552, 91-97
    DOI 10.1016/j.bbrc.2021.02.099, PubMed 33744765
  66. Stjepanovic N, Lubinski J, Moller P, Randall Armel S, Foulkes WD, Tung N, Neuhausen SL, Kotsopoulos J, Sun P, Sun S, Eisen A, Narod SA, Hereditary Breast Cancer Clinical Study Group (2021)
    Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers
    Breast Cancer Res Treat, 187 (2), 515-523
    DOI 10.1007/s10549-020-06072-9, PubMed 33423179
  67. Sveen A, Johannessen B, Eilertsen IA, Røsok BI, Gulla M, Eide PW, Bruun J, Kryeziu K, Meza-Zepeda LA, Myklebost O, Bjørnbeth BA, Skotheim RI, Nesbakken A, Lothe RA (2021)
    The expressed mutational landscape of microsatellite stable colorectal cancers
    Genome Med, 13 (1), 142
    DOI 10.1186/s13073-021-00955-2, PubMed 34470667
  68. Svendsen HA, Meling TR, Nygaard V, Waagene S, Russnes H, Juell S, Rogne SG, Pahnke J, Helseth E, Fodstad Ø, Maelandsmo GM (2021)
    Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin
    Cancer Med, 10 (23), 8604-8613
    DOI 10.1002/cam4.4334, PubMed 34612023
  69. Szybowska P, Kostas M, Wesche J, Haugsten EM, Wiedlocha A (2021)
    Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling
    Cells, 10 (6)
    DOI 10.3390/cells10061342, PubMed 34071546
  70. Sønstevold T, Engedal N, Torgersen ML (2021)
    Perturbation of Cellular Redox Homeostasis Dictates Divergent Effects of Polybutyl Cyanoacrylate (PBCA) Nanoparticles on Autophagy
    Cells, 10 (12)
    DOI 10.3390/cells10123432, PubMed 34943939
  71. Sørensen O, Andersen AM, Larsen SG, Giercksky KE, Flatmark K (2021)
    Correction to: Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of highgrade pseudomyxoma peritonei
    Clin Exp Metastasis, 38 (2), 253
    DOI 10.1007/s10585-021-10084-0, PubMed 33649933
  72. Tamhane T, Njenga RW, Burden RE, Bueth H, Maelandsmo GM, Haugen MH, Scott CJ, Brix K (2021)
    Trafficking of Full-Length and N-Terminally Truncated Cathepsin B in Human Colorectal Carcinoma Cells
    Appl. Sci.-Basel, 11 (24), 11936
    DOI 10.3390/app112411936
  73. Thorgersen EB, Asvall J, Frøysnes IS, Schjalm C, Larsen SG, Dueland S, Andersson Y, Fodstad Ø, Mollnes TE, Flatmark K (2021)
    Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
    Ann Surg Oncol, 28 (9), 5252-5262
    DOI 10.1245/s10434-021-10022-0, PubMed 34019185
  74. Thorgersen EB, Flatmark K (2021)
    ASO Author Reflections: The Peritoneum is an Active Immunological Compartment
    Ann Surg Oncol, 28 (9), 5263-5264
    DOI 10.1245/s10434-021-10036-8, PubMed 33939046
  75. Torices L, de Las Heras J, Arango-Lasprilla JC, Cortés JM, Nunes-Xavier CE, Pulido R (2021)
    MMADHC premature termination codons in the pathogenesis of cobalamin D disorder: Potential of translational readthrough reconstitution
    Mol Genet Metab Rep, 26, 100710
    DOI 10.1016/j.ymgmr.2021.100710, PubMed 33552904
  76. Taavitsainen S, Engedal N, Cao S, Handle F, Erickson A, Prekovic S, Wetterskog D, Tolonen T, Vuorinen EM, Kiviaho A, Nätkin R, Häkkinen T, Devlies W, Henttinen S, Kaarijärvi R, Lahnalampi M, Kaljunen H, Nowakowska K, Syvälä H, Bläuer M, Cremaschi P, Claessens F, Visakorpi T, Tammela TLJ, Murtola T et al. (2021)
    Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
    Nat Commun, 12 (1), 5307
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  77. Valsalakumari R, Yadava SK, Szwed M, Pandya AD, Mælandsmo GM, Torgersen ML, Iversen TG, Skotland T, Sandvig K, Giri J (2021)
    Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
    Int J Pharm, 597, 120217
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  78. van der Zanden TM, Mooij MG, Vet NJ, Neubert A, Rascher W, Lagler FB, Male C, Grytli H, Halvorsen T, de Hoog M, de Wildt SN (2021)
    Benefit-Risk Assessment of Off-Label Drug Use in Children: The Bravo Framework
    Clin Pharmacol Ther, 110 (4), 952-965
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  79. Vikan AK, Kostas M, Haugsten EM, Selbo PK, Wesche J (2021)
    Efficacy and Selectivity of FGF2-Saporin Cytosolically Delivered by PCI in Cells Overexpressing FGFR1
    Cells, 10 (6)
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  80. Wang N, Bai D, Kristiansen E, Deng R, Zhang S (2021)
    AKIP1 promotes tumor progression by cancer-related pathways and predicts prognosis in tongue squamous cell carcinoma
    Am J Transl Res, 13 (11), 12338-12351
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    Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation
    Cells, 10 (9)
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    Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial
    Front Immunol, 12, 663865
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Publications 2020

  1. Aghayan DL, Kazaryan AM, Dagenborg VJ, Røsok BI, Fagerland MW, Waaler Bjørnelv GM, Kristiansen R, Flatmark K, Fretland ÅA, Edwin B, OSLO-COMET Survival Study Collaborators (2020)
    Long-Term Oncologic Outcomes After Laparoscopic Versus Open Resection for Colorectal Liver Metastases : A Randomized Trial
    Ann Intern Med, 174 (2), 175-182
    DOI 10.7326/M20-4011, PubMed 33197213
  2. Ahadova A, Seppälä TT, Engel C, Gallon R, Burn J, Holinski-Feder E, Steinke-Lange V, Möslein G, Nielsen M, Ten Broeke SW, Laghi L, Dominguez-Valentin M, Capella G, Macrae F, Scott R, Hüneburg R, Nattermann J, Hoffmeister M, Brenner H, Bläker H, von Knebel Doeberitz M, Sampson JR, Vasen H, Mecklin JP, Møller P et al. (2020)
    The "unnatural" history of colorectal cancer in Lynch syndrome: Lessons from colonoscopy surveillance
    Int J Cancer, 148 (4), 800-811
    DOI 10.1002/ijc.33224, PubMed 32683684
  3. Álvarez K, Orellana P, De la Fuente M, Canales T, Pinto E, Heine C, Solar B, Hurtado C, Møller P, Kronberg U, Zarate AJ, Dominguez-Valentin M, López-Köstner F (2020)
    Spectrum and Frequency of Tumors, Cancer Risk and Survival in Chilean Families with Lynch Syndrome: Experience of the Implementation of a Registry
    J Clin Med, 9 (6)
    DOI 10.3390/jcm9061861, PubMed 32549215
  4. Arstad C, Taskén K, Refinetti P, Axcrona U, Giercksky KE, Ekstrøm PO (2020)
    Somatic Mitochondrial DNA Point Mutations Used as Biomarkers to Demonstrate Genomic Heterogeneity in Primary Prostate Cancer
    Prostate Cancer, 2020, 7673684
    DOI 10.1155/2020/7673684, PubMed 32908706
  5. Barkovskaya A, Seip K, Prasmickaite L, Mills IG, Moestue SA, Itkonen HM (2020)
    Inhibition of O-GlcNAc transferase activates tumor-suppressor gene expression in tamoxifen-resistant breast cancer cells
    Sci Rep, 10 (1), 16992
    DOI 10.1038/s41598-020-74083-z, PubMed 33046784
  6. Chen B, Dragomir MP, Fabris L, Bayraktar R, Knutsen E, Liu X, Tang C, Li Y, Shimura T, Ivkovic TC, De Los Santos MC, Anfossi S, Shimizu M, Shah MY, Ling H, Shen P, Multani AS, Pardini B, Burks JK, Katayama H, Reineke LC, Huo L, Syed M, Song S, Ferracin M et al. (2020)
    The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling
    Gastroenterology, 159 (6), 2146-2162.e33
    DOI 10.1053/j.gastro.2020.08.018, PubMed 32805281
  7. Dagenborg VJ, Marshall SE, Yaqub S, Grzyb K, Boye K, Lund-Iversen M, Høye E, Berstad AE, Fretland ÅA, Edwin B, Ree AH, Flatmark K (2020)
    Neoadjuvant chemotherapy is associated with a transient increase of intratumoral T-cell density in microsatellite stable colorectal liver metastases
    Cancer Biol Ther, 21 (5), 432-440
    DOI 10.1080/15384047.2020.1721252, PubMed 32098573
  8. De Las Heras J, Diez I, Jimenez-Marin A, Cabrera A, Ramos-Usuga D, Diaz-Fernandez MV, Torices L, Nunes-Xavier CE, Pulido R, Arango-Lasprilla JC, Cortes JM (2020)
    Brain Circuit Alterations and Cognitive Disability in Late-Onset Cobalamin D Disorder
    J Clin Med, 9 (4)
    DOI 10.3390/jcm9040990, PubMed 32252256
  9. Dillard P, Köksal H, Maggadottir SM, Winge-Main A, Pollmann S, Menard M, Myhre MR, Mælandsmo GM, Flørenes VA, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2020)
    Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
    Mol Ther, 29 (3), 1199-1213
    DOI 10.1016/j.ymthe.2020.11.019, PubMed 33212301
  10. Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Nakken S, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2020)
    Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
    Genet Med, 23 (4), 705-712
    DOI 10.1038/s41436-020-01029-1, PubMed 33257847
  11. Dominguez-Valentin M, Sampson JR, Møller P, Seppälä TT, PLSD Collaborators (2020)
    Analysis in the Prospective Lynch Syndrome Database identifies sarcoma as part of the Lynch syndrome tumor spectrum
    Int J Cancer, 148 (2), 512-513
    DOI 10.1002/ijc.33214, PubMed 32783184
  12. Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A et al. (2020)
    Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
    Genet Med, 22 (9), 1569
    DOI 10.1038/s41436-020-0892-4, PubMed 32690931
  13. Dominguez-Valentin M, Seppälä TT, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W, Vangala D et al. (2020)
    Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database
    J Clin Med, 9 (7)
    DOI 10.3390/jcm9072290, PubMed 32708519
  14. Flatmark K, Mohamed F (2020)
    ASO Author Reflections: Estimating the Prevalence of Pseudomyxoma Peritonei in Europe Using a Novel Statistical Method
    Ann Surg Oncol, 27 (Suppl 3), 771-772
    DOI 10.1245/s10434-020-08691-4, PubMed 32495284
  15. Flem-Karlsen K, Fodstad Ø, Nunes-Xavier CE (2020)
    B7-H3 Immune Checkpoint Protein in Human Cancer
    Curr Med Chem, 27 (24), 4062-4086
    DOI 10.2174/0929867326666190517115515, PubMed 31099317
  16. Flem-Karlsen K, Nyakas M, Farstad IN, McFadden E, Wernhoff P, Jacobsen KD, Flørenes VA, Mælandsmo GM (2020)
    Soluble AXL as a marker of disease progression and survival in melanoma
    PLoS One, 15 (1), e0227187
    DOI 10.1371/journal.pone.0227187, PubMed 31917795
  17. Fleten KG, Lund-Andersen C, Waagene S, Abrahamsen TW, Mørch Y, Boye K, Torgunrud A, Flatmark K (2020)
    Experimental Treatment of Mucinous Peritoneal Metastases Using Patient-Derived Xenograft Models
    Transl Oncol, 13 (8), 100793
    DOI 10.1016/j.tranon.2020.100793, PubMed 32447231
  18. Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2020)
    MirGeneDB 2.0: the metazoan microRNA complement
    Nucleic Acids Res, 48 (D1), D132-D141
    DOI 10.1093/nar/gkz885, PubMed 31598695
  19. Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2020)
    MirGeneDB 2.0: the metazoan microRNA complement
    Nucleic Acids Res, 48 (D1), D1172
    DOI 10.1093/nar/gkz1016, PubMed 31642479
  20. Georgiesh T, Boye K, Bjerkehagen B (2020)
    A novel risk score to predict early and late recurrence in solitary fibrous tumour
    Histopathology, 77 (1), 123-132
    DOI 10.1111/his.14078, PubMed 31991494
  21. Guldvik IJ, Zuber V, Braadland PR, Grytli HH, Ramberg H, Lilleby W, Thiede B, Zucknick M, Saatcioglu F, Gislefoss R, Kvåle R, George A, Grönberg H, Wiklund F, Neal DE, Gnanapragasam VJ, Taskén KA, Mills IG (2020)
    Identification and Validation of Leucine-rich α-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification
    Eur Urol Open Sci, 21, 51-60
    DOI 10.1016/j.euros.2020.08.007, PubMed 34337468
  22. Halvorsen AR, Haugen MH, Öjlert ÅK, Lund-Iversen M, Jørgensen L, Solberg S, Mælandsmo GM, Brustugun OT, Helland Å (2020)
    Protein Kinase C Isozymes Associated With Relapse Free Survival in Non-Small Cell Lung Cancer Patients
    Front Oncol, 10, 590755
    DOI 10.3389/fonc.2020.590755, PubMed 33324562
  23. Hernández-Sandoval JA, Gutiérrez-Angulo M, Magaña-Torres MT, Alvizo-Rodríguez CR, Ramírez-Plascencia HHF, Flores-López BA, Valenzuela-Pérez JA, Peregrina-Sandoval J, Moreno-Ortiz JM, Domínguez-Valentín M, Ayala-Madrigal ML (2020)
    Prevalence of the BRAF p.v600e variant in patients with colorectal cancer from Mexico and its estimated frequency in Latin American and Caribbean populations
    J Investig Med, 68 (5), 985-991
    DOI 10.1136/jim-2020-001301, PubMed 32184228
  24. Humbert M, Morán M, de la Cruz-Ojeda P, Muntané J, Wiedmer T, Apostolova N, McKenna SL, Velasco G, Balduini W, Eckhart L, Janji B, Sampaio-Marques B, Ludovico P, Žerovnik E, Langer R, Perren A, Engedal N, Tschan MP (2020)
    Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot
    Biology (Basel), 9 (3)
    DOI 10.3390/biology9030059, PubMed 32245178
  25. Itkonen HM, Poulose N, Steele RE, Martin SES, Levine ZG, Duveau DY, Carelli R, Singh R, Urbanucci A, Loda M, Thomas CJ, Mills IG, Walker S (2020)
    Inhibition of O-GlcNAc Transferase Renders Prostate Cancer Cells Dependent on CDK9
    Mol Cancer Res, 18 (10), 1512-1521
    DOI 10.1158/1541-7786.MCR-20-0339, PubMed 32611550
  26. Knutsen E, Lellahi SM, Aure MR, Nord S, Fismen S, Larsen KB, Gabriel MT, Hedberg A, Bjørklund SS, Oslo Breast Cancer Research Consortium (OSBREAC), Bofin AM, Mælandsmo GM, Sørlie T, Mortensen ES, Perander M (2020)
    The expression of the long NEAT1_2 isoform is associated with human epidermal growth factor receptor 2-positive breast cancers
    Sci Rep, 10 (1), 1277
    DOI 10.1038/s41598-020-57759-4, PubMed 31992741
  27. Kohvakka A, Sattari M, Shcherban A, Annala M, Urbanucci A, Kesseli J, Tammela TLJ, Kivinummi K, Latonen L, Nykter M, Visakorpi T (2020)
    AR and ERG drive the expression of prostate cancer specific long noncoding RNAs
    Oncogene, 39 (30), 5241-5251
    DOI 10.1038/s41388-020-1365-6, PubMed 32555329
  28. Kotsopoulos J, Karlan B, Gronwald J, Hall E, Moller P, Tung N, Zakalik D, Foulkes WD, Rosen B, Neuhausen SL, Sun P, Lubinksi J, Narod SA (2020)
    Long-term outcomes following a diagnosis of ovarian cancer at the time of preventive oophorectomy among BRCA1 and BRCA2 mutation carriers
    Int J Gynecol Cancer, 30 (6), 825-830
    DOI 10.1136/ijgc-2019-001141, PubMed 32354794
  29. Kramer I, Hooning MJ, Mavaddat N, Hauptmann M, Keeman R, Steyerberg EW, Giardiello D, Antoniou AC, Pharoah PDP, Canisius S, Abu-Ful Z, Andrulis IL, Anton-Culver H, Aronson KJ, Augustinsson A, Becher H, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bogdanova NV, Bojesen SE, Bolla MK, Bonanni B, Brauch H et al. (2020)
    Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk
    Am J Hum Genet, 107 (5), 837-848
    DOI 10.1016/j.ajhg.2020.09.001, PubMed 33022221
  30. Lavelle TJ, Alver TN, Heintz KM, Wernhoff P, Nygaard V, Nakken S, Øy GF, Bøe SL, Urbanucci A, Hovig E (2020)
    Dysregulation of MITF Leads to Transformation in MC1R-Defective Melanocytes
    Cancers (Basel), 12 (7)
    DOI 10.3390/cancers12071719, PubMed 32605315
  31. Lien VT, Kristiansen MK, Pettersen S, Haugen MH, Krauss S, Olberg DE, Waaler J, Klaveness J (2020)
    Correction: Towards dual inhibitors of the MET kinase and WNT signaling pathway; design, synthesis and biological evaluation
    RSC Adv, 10 (9), 4927
    DOI 10.1039/d0ra90007a, PubMed 35503286
  32. Meltzer S, Bjørnetrø T, Lyckander LG, Flatmark K, Dueland S, Samiappan R, Johansen C, Kalanxhi E, Ree AH, Redalen KR (2020)
    Corrigendum to "Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer" [Transl Oncol 12 (8) (2019) 1038-1044]
    Transl Oncol, 13 (1), 122-124
    DOI 10.1016/j.tranon.2019.09.005, PubMed 31843135
  33. Møller P (2020)
    The Prospective Lynch Syndrome Database reports enable evidence-based personal precision health care
    Hered Cancer Clin Pract, 18, 6
    DOI 10.1186/s13053-020-0138-0, PubMed 32190163
  34. Møller P, Dominguez-Valentin M, Rødland EA, Hovig E (2020)
    Correction: Møller, P.; et al. Causes for Frequent Pathogenic BRCA1 Variants Include Low Penetrance in Fertile Ages, Recurrent De-Novo Mutations and Genetic Drift. Cancers 2019, 11, 132
    Cancers (Basel), 12 (2)
    DOI 10.3390/cancers12020410, PubMed 32050665
  35. Møller P, Sampson J, Dominguez-Valentin M, Burn J, Sunde L, Möslein G, Mecklin JP, Seppälä T (2020)
    Letter to the Editor-Recent advances in Lynch syndrome
    Fam Cancer, 20 (2), 117-118
    DOI 10.1007/s10689-020-00200-6, PubMed 32770425
  36. Olafsdottir EJ, Borg A, Jensen MB, Gerdes AM, Johansson ALV, Barkardottir RB, Johannsson OT, Ejlertsen B, Sønderstrup IMH, Hovig E, Lænkholm AV, Hansen TVO, Olafsdottir GH, Rossing M, Jonasson JG, Sigurdsson S, Loman N, Nilsson MP, Narod SA, Tryggvadottir L (2020)
    Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status
    Br J Cancer, 123 (11), 1608-1615
    DOI 10.1038/s41416-020-01056-4, PubMed 32939053
  37. Pace M, Falappa M, Freschi A, Balzani E, Berteotti C, Lo Martire V, Kaveh F, Hovig E, Zoccoli G, Amici R, Cerri M, Urbanucci A, Tucci V (2020)
    Loss of Snord116 impacts lateral hypothalamus, sleep, and food-related behaviors
    JCI Insight, 5 (12)
    DOI 10.1172/jci.insight.137495, PubMed 32365348
  38. Pandya AD, Øverbye A, Sahariah P, Gaware VS, Høgset H, Masson M, Høgset A, Mælandsmo GM, Skotland T, Sandvig K, Iversen TG (2020)
    Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer
    Biomacromolecules, 21 (4), 1489-1498
    DOI 10.1021/acs.biomac.0c00061, PubMed 32092254
  39. Patrick-Brown TDJH, Carr NJ, Swanson DM, Larsen S, Mohamed F, Flatmark K (2020)
    Estimating the Prevalence of Pseudomyxoma Peritonei in Europe Using a Novel Statistical Method
    Ann Surg Oncol, 28 (1), 252-257
    DOI 10.1245/s10434-020-08655-8, PubMed 32488520
  40. Piñero TA, Soukarieh O, Rolain M, Alvarez K, López-Köstner F, Torrezan GT, Carraro DM, De Oliveira Nascimento IL, Bomfim TF, Machado-Lopes TMB, Freitas JC, Toralles MB, Sandes KA, Rossi BM, Junior SA, Meira J, Dominguez-Valentin M, Møller P, Vaccaro CA, Martins A, Pavicic WH (2020)
    MLH1 intronic variants mapping to + 5 position of splice donor sites lead to deleterious effects on RNA splicing
    Fam Cancer, 19 (4), 323-336
    DOI 10.1007/s10689-020-00182-5, PubMed 32363481
  41. Ree AH, Nygaard V, Boye K, Heinrich D, Dueland S, Bergheim IR, Johansen C, Beiske K, Negård A, Lund-Iversen M, Nygaard V, Hovig E, Nakken S, Nasser S, Julsrud L, Reisse CH, Ruud EA, Kristensen VN, Flørenes VA, Geitvik GA, Lingjærde OC, Børresen-Dale AL, Russnes HG, Mælandsmo GM, Flatmark K (2020)
    Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer - the MetAction study
    Acta Oncol, 59 (7), 733-740
    DOI 10.1080/0284186X.2020.1742377, PubMed 32208873
  42. Refinetti P, Morgenthaler S, Thilly WG, Arstad C, Ekstrøm PO (2020)
    Tracing of Human Tumor Cell Lineages by Mitochondrial Mutations
    Front Oncol, 10, 523860
    DOI 10.3389/fonc.2020.523860, PubMed 33344219
  43. Saeednejad Zanjani L, Madjd Z, Axcrona U, Abolhasani M, Rasti A, Asgari M, Fodstad Ø, Andersson Y (2020)
    Cytoplasmic expression of B7-H3 and membranous EpCAM expression are associated with higher grade and survival outcomes in patients with clear cell renal cell carcinoma
    Ann Diagn Pathol, 46, 151483
    DOI 10.1016/j.anndiagpath.2020.151483, PubMed 32143173
  44. Salgado D, Armean IM, Baudis M, Beltran S, Capella-Gutierrez S, Carvalho-Silva D, Dominguez Del Angel V, Dopazo J, Furlong LI, Gao B, Garcia L, Gerloff D, Gut I, Gyenesei A, Habermann N, Hancock JM, Hanauer M, Hovig E, Johansson LF, Keane T, Korbel J, Lauer KB, Laurie S, Leskošek B, Lloyd D et al. (2020)
    The ELIXIR Human Copy Number Variations Community: building bioinformatics infrastructure for research
    F1000Res, 9
    DOI 10.12688/f1000research.24887.1, PubMed 34367618
  45. Seppälä TT, Dominguez-Valentin M, Sampson JR, Møller P (2020)
    Prospective observational data informs understanding and future management of Lynch syndrome: insights from the Prospective Lynch Syndrome Database (PLSD)
    Fam Cancer, 20 (1), 35-39
    DOI 10.1007/s10689-020-00193-2, PubMed 32507935
  46. Serguienko A, Braadland P, Meza-Zepeda LA, Bjerkehagen B, Myklebost O (2020)
    Accurate 3-gene-signature for early diagnosis of liposarcoma progression
    Clin Sarcoma Res, 10, 4
    DOI 10.1186/s13569-020-0126-1, PubMed 32158531
  47. Steinhaeuser SS, Morera E, Budkova Z, Schepsky A, Wang Q, Rolfsson O, Riedel A, Krueger A, Hilmarsdottir B, Maelandsmo GM, Valdimarsdottir B, Sigurdardottir AK, Agnarsson BA, Jonasson JG, Ingthorsson S, Traustadottir GA, Oskarsson T, Gudjonsson T (2020)
    ECM1 secreted by HER2-overexpressing breast cancer cells promotes formation of a vascular niche accelerating cancer cell migration and invasion
    Lab Invest, 100 (7), 928-944
    DOI 10.1038/s41374-020-0415-6, PubMed 32203150
  48. Sønstevold T, Engedal N, Mørch Ý, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2020)
    Structural Variants of poly(alkylcyanoacrylate) Nanoparticles Differentially Affect LC3 and Autophagic Cargo Degradation
    J Biomed Nanotechnol, 16 (4), 432-445
    DOI 10.1166/jbn.2020.2906, PubMed 32970976
  49. Tadele DS, Robertson J, Crispin R, Herrera MC, Chlubnová M, Piechaczyk L, Ayuda-Durán P, Singh SK, Gedde-Dahl T, Fløisand Y, Skavland J, Wesche J, Gjertsen BT, Enserink JM (2020)
    A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
    J Biol Chem, 296, 100179
    DOI 10.1074/jbc.RA120.015285, PubMed 33303632
  50. Torgersen ML, Judge PJ, Bada Juarez JF, Pandya AD, Fusser M, Davies CW, Maciejewska MK, Yin DJ, Maelandsmo GM, Skotland T, Watts A, Sandvig K (2020)
    Physicochemical Characterization, Toxicity and In Vivo Biodistribution Studies of a Discoidal, Lipid-Based Drug Delivery Vehicle: Lipodisq Nanoparticles Containing Doxorubicin
    J Biomed Nanotechnol, 16 (4), 419-431
    DOI 10.1166/jbn.2020.2911, PubMed 32970975
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    Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
    Blood Adv, 4 (9), 1859-1866
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    Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models
    Commun Biol, 3 (1), 196
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    Accuracy and efficiency of germline variant calling pipelines for human genome data
    Sci Rep, 10 (1), 20222
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Publications 2019

  1. Abrahamsson H, Porojnicu AC, Lindstrøm JC, Dueland S, Flatmark K, Hole KH, Seierstad T, Moan J, Redalen KR, Meltzer S, Ree AH (2019)
    High level of circulating vitamin D during neoadjuvant therapy may lower risk of metastatic progression in high-risk rectal cancer
    BMC Cancer, 19 (1), 488
    DOI 10.1186/s12885-019-5724-z, PubMed 31122213
  2. Aghayan DL, Fretland ÅA, Kazaryan AM, Sahakyan MA, Dagenborg VJ, Bjørnbeth BA, Flatmark K, Kristiansen R, Edwin B (2019)
    Laparoscopic versus open liver resection in the posterosuperior segments: a sub-group analysis from the OSLO-COMET randomized controlled trial
    HPB (Oxford), 21 (11), 1485-1490
    DOI 10.1016/j.hpb.2019.03.358, PubMed 30962136
  3. Andersson Y, Inderberg EM, Kvalheim G, Herud TM, Engebraaten O, Flatmark K, Dueland S, Fodstad Ø (2019)
    Immune stimulatory effect of anti-EpCAM immunotoxin - improved overall survival of metastatic colorectal cancer patients
    Acta Oncol, 59 (4), 404-409
    DOI 10.1080/0284186X.2019.1704864, PubMed 31876430
  4. Bains SJ, Abrahamsson H, Flatmark K, Dueland S, Hole KH, Seierstad T, Redalen KR, Meltzer S, Ree AH (2019)
    Immunogenic cell death by neoadjuvant oxaliplatin and radiation protects against metastatic failure in high-risk rectal cancer
    Cancer Immunol Immunother, 69 (3), 355-364
    DOI 10.1007/s00262-019-02458-x, PubMed 31893287
  5. Barkovskaya A, Seip K, Hilmarsdottir B, Maelandsmo GM, Moestue SA, Itkonen HM (2019)
    O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes
    Sci Rep, 9 (1), 5670
    DOI 10.1038/s41598-019-42153-6, PubMed 30952976
  6. Briem E, Ingthorsson S, Traustadottir GA, Hilmarsdottir B, Gudjonsson T (2019)
    Application of the D492 Cell Lines to Explore Breast Morphogenesis, EMT and Cancer Progression in 3D Culture
    J Mammary Gland Biol Neoplasia, 24 (2), 139-147
    DOI 10.1007/s10911-018-09424-w, PubMed 30684066
  7. Brudvik KW, Jones RP, Giuliante F, Shindoh J, Passot G, Chung MH, Song J, Li L, Dagenborg VJ, Fretland ÅA, Røsok B, De Rose AM, Ardito F, Edwin B, Panettieri E, Larocca LM, Yamashita S, Conrad C, Aloia TA, Poston GJ, Bjørnbeth BA, Vauthey JN (2019)
    RAS Mutation Clinical Risk Score to Predict Survival After Resection of Colorectal Liver Metastases
    Ann Surg, 269 (1), 120-126
    DOI 10.1097/SLA.0000000000002319, PubMed 28549012
  8. Braadland PR, Ramberg H, Grytli HH, Urbanucci A, Nielsen HK, Guldvik IJ, Engedal A, Ketola K, Wang W, Svindland A, Mills IG, Bjartell A, Taskén KA (2019)
    The β2-Adrenergic Receptor Is a Molecular Switch for Neuroendocrine Transdifferentiation of Prostate Cancer Cells
    Mol Cancer Res, 17 (11), 2154-2168
    DOI 10.1158/1541-7786.MCR-18-0605, PubMed 31395667
  9. Braadland PR, Urbanucci A (2019)
    Chromatin reprogramming as an adaptation mechanism in advanced prostate cancer
    Endocr Relat Cancer, 26 (4), R211-R235
    DOI 10.1530/ERC-18-0579, PubMed 30844748
  10. Calvete J, Larrinaga G, Errarte P, Martín AM, Dotor A, Esquinas C, Nunes-Xavier CE, Pulido R, López JI, Angulo JC (2019)
    The coexpression of fibroblast activation protein (FAP) and basal-type markers (CK 5/6 and CD44) predicts prognosis in high-grade invasive urothelial carcinoma of the bladder
    Hum Pathol, 91, 61-68
    DOI 10.1016/j.humpath.2019.07.002, PubMed 31279874
  11. Camilio KA, Wang MY, Mauseth B, Waagene S, Kvalheim G, Rekdal Ø, Sveinbjørnsson B, Mælandsmo GM (2019)
    Combining the oncolytic peptide LTX-315 with doxorubicin demonstrates therapeutic potential in a triple-negative breast cancer model
    Breast Cancer Res, 21 (1), 9
    DOI 10.1186/s13058-018-1092-x, PubMed 30670061
  12. Crosbie EJ, Ryan NAJ, Arends MJ, Bosse T, Burn J, Cornes JM, Crawford R, Eccles D, Frayling IM, Ghaem-Maghami S, Hampel H, Kauff ND, Kitchener HC, Kitson SJ, Manchanda R, McMahon RFT, Monahan KJ, Menon U, Møller P, Möslein G, Rosenthal A, Sasieni P, Seif MW, Singh N, Skarrott P et al. (2019)
    The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome
    Genet Med, 21 (10), 2390-2400
    DOI 10.1038/s41436-019-0489-y, PubMed 30918358
  13. Debik J, Euceda LR, Lundgren S, Gythfeldt HVL, Garred Ø, Borgen E, Engebraaten O, Bathen TF, Giskeødegård GF (2019)
    Assessing Treatment Response and Prognosis by Serum and Tissue Metabolomics in Breast Cancer Patients
    J Proteome Res, 18 (10), 3649-3660
    DOI 10.1021/acs.jproteome.9b00316, PubMed 31483662
  14. Della Valle A, Rossi BM, Palmero EI, Antelo M, Vaccaro CA, López-Kostner F, Alvarez K, Cruz-Correa M, Bruno LI, Forones NM, Mindiola JAR, Buleje J, Spirandelli F, Bohorquez M, Cock-Rada AM, Sullcahuaman Y, Nascimento I, Abe-Sandes K, Lino-Silva LS, Petracchi F, Mampel A, Rodriguez Y, Rossi NT, Yañez CB, Rubio C et al. (2019)
    A snapshot of current genetic testing practice in Lynch syndrome: The results of a representative survey of 33 Latin American existing centres/registries
    Eur J Cancer, 119, 112-121
    DOI 10.1016/j.ejca.2019.07.017, PubMed 31442815
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    Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy
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    Precise Immunodetection of PTEN Protein in Human Neoplasia
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    DOI 10.3390/ijms20081826, PubMed 31013829

Publications 2018

  1. Aurtenetxe O, Zaldumbide L, Erramuzpe A, López R, López JI, Cortés JM, Pulido R, Nunes-Xavier CE (2018)
    DUSP5 expression associates with poor prognosis in human neuroblastoma
    Exp Mol Pathol, 105 (3), 272-278
    DOI 10.1016/j.yexmp.2018.08.008, PubMed 30171833
  2. Berg J, Halvorsen AR, Bengtson MB, Taskén KA, Mælandsmo GM, Yndestad A, Halvorsen B, Brustugun OT, Aukrust P, Ueland T, Helland Å (2018)
    Levels and prognostic impact of circulating markers of inflammation, endothelial activation and extracellular matrix remodelling in patients with lung cancer and chronic obstructive pulmonary disease
    BMC Cancer, 18 (1), 739
    DOI 10.1186/s12885-018-4659-0, PubMed 30005623
  3. Birkeland E, Zhang S, Poduval D, Geisler J, Nakken S, Vodak D, Meza-Zepeda LA, Hovig E, Myklebost O, Knappskog S, Lønning PE (2018)
    Patterns of genomic evolution in advanced melanoma
    Nat Commun, 9 (1), 2665
    DOI 10.1038/s41467-018-05063-1, PubMed 29991680
  4. Bousquet PA, Meltzer S, Sønstevold L, Esbensen Y, Dueland S, Flatmark K, Sitter B, Bathen TF, Seierstad T, Redalen KR, Eide L, Ree AH (2018)
    Markers of Mitochondrial Metabolism in Tumor Hypoxia, Systemic Inflammation, and Adverse Outcome of Rectal Cancer
    Transl Oncol, 12 (1), 76-83
    DOI 10.1016/j.tranon.2018.09.010, PubMed 30273860
  5. Boye K, Berner JM, Hompland I, Bruland ØS, Stoldt S, Sundby Hall K, Bjerkehagen B, Hølmebakk T (2018)
    Genotype and risk of tumour rupture in gastrointestinal stromal tumour
    Br J Surg, 105 (2), e169-e175
    DOI 10.1002/bjs.10743, PubMed 29341147
  6. Briem E, Budkova Z, Sigurdardottir AK, Hilmarsdottir B, Kricker J, Timp W, Magnusson MK, Traustadottir GA, Gudjonsson T (2018)
    MiR-203a is differentially expressed during branching morphogenesis and EMT in breast progenitor cells and is a repressor of peroxidasin
    Mech Dev, 155, 34-47
    DOI 10.1016/j.mod.2018.11.002, PubMed 30508578
  7. Braadland PR, Giskeødegård G, Sandsmark E, Bertilsson H, Euceda LR, Hansen AF, Guldvik IJ, Selnæs KM, Grytli HH, Katz B, Svindland A, Bathen TF, Eri LM, Nygård S, Berge V, Taskén KA, Tessem MB (2018)
    Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
    Br J Cancer, 118 (6), e11
    DOI 10.1038/bjc.2017.470, PubMed 29462127
  8. Bråte J, Neumann RS, Fromm B, Haraldsen AAB, Tarver JE, Suga H, Donoghue PCJ, Peterson KJ, Ruiz-Trillo I, Grini PE, Shalchian-Tabrizi K (2018)
    Unicellular Origin of the Animal MicroRNA Machinery
    Curr Biol, 28 (20), 3288-3295.e5
    DOI 10.1016/j.cub.2018.08.018, PubMed 30318349
  9. Dominguez-Valentin M, Evans DGR, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
    Genetic variants of prospectively demonstrated phenocopies in BRCA1/2 kindreds
    Hered Cancer Clin Pract, 16, 4
    DOI 10.1186/s13053-018-0086-0, PubMed 29371908
  10. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
    Potentially pathogenic germline CHEK2 c.319+2T>A among multiple early-onset cancer families
    Fam Cancer, 17 (1), 141-153
    DOI 10.1007/s10689-017-0011-0, PubMed 28608266
  11. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
    Identification of genetic variants for clinical management of familial colorectal tumors
    BMC Med Genet, 19 (1), 26
    DOI 10.1186/s12881-018-0533-9, PubMed 29458332
  12. Ebenesersdóttir SS, Sandoval-Velasco M, Gunnarsdóttir ED, Jagadeesan A, Guðmundsdóttir VB, Thordardóttir EL, Einarsdóttir MS, Moore KHS, Sigurðsson Á, Magnúsdóttir DN, Jónsson H, Snorradóttir S, Hovig E, Møller P, Kockum I, Olsson T, Alfredsson L, Hansen TF, Werge T, Cavalleri GL, Gilbert E, Lalueza-Fox C, Walser JW, Kristjánsdóttir S, Gopalakrishnan S et al. (2018)
    Ancient genomes from Iceland reveal the making of a human population
    Science, 360 (6392), 1028-1032
    DOI 10.1126/science.aar2625, PubMed 29853688
  13. Eng MS, Kaur J, Prasmickaite L, Engesæter BØ, Weyergang A, Skarpen E, Berg K, Rosenblum MG, Mælandsmo GM, Høgset A, Ferrone S, Selbo PK (2018)
    Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins
    Photochem Photobiol Sci, 17 (5), 539-551
    DOI 10.1039/C7PP00358G, PubMed 29565434
  14. Fafilek B, Balek L, Bosakova MK, Varecha M, Nita A, Gregor T, Gudernova I, Krenova J, Ghosh S, Piskacek M, Jonatova L, Cernohorsky NH, Zieba JT, Kostas M, Haugsten EM, Wesche J, Erneux C, Trantirek L, Krakow D, Krejci P (2018)
    The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases
    Sci Signal, 11 (548)
    DOI 10.1126/scisignal.aap8608, PubMed 30228226
  15. Flem-Karlsen K, Fodstad Ø, Tan M, Nunes-Xavier CE (2018)
    B7-H3 in Cancer - Beyond Immune Regulation
    Trends Cancer, 4 (6), 401-404
    DOI 10.1016/j.trecan.2018.03.010, PubMed 29860983
  16. Fretland ÅA, Dagenborg VJ, Bjørnelv GMW, Kazaryan AM, Kristiansen R, Fagerland MW, Hausken J, Tønnessen TI, Abildgaard A, Barkhatov L, Yaqub S, Røsok BI, Bjørnbeth BA, Andersen MH, Flatmark K, Aas E, Edwin B (2018)
    Laparoscopic Versus Open Resection for Colorectal Liver Metastases: The OSLO-COMET Randomized Controlled Trial
    Ann Surg, 267 (2), 199-207
    DOI 10.1097/SLA.0000000000002353, PubMed 28657937
  17. Fromm B, Kang W, Rovira C, Cayota A, Witwer K, Friedländer MR, Tosar JP (2018)
    Plant microRNAs in human sera are likely contaminants
    J Nutr Biochem, 65, 139-140
    DOI 10.1016/j.jnutbio.2018.07.019, PubMed 30266285
  18. Fromm B, Tosar JP, Lu Y, Halushka MK, Witwer KW (2018)
    Human and Cow Have Identical miR-21-5p and miR-30a-5p Sequences, Which Are Likely Unsuited to Study Dietary Uptake from Cow Milk
    J Nutr, 148 (9), 1506-1507
    DOI 10.1093/jn/nxy144, PubMed 30184228
  19. Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2018)
    Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft
    J Control Release, 293, 183-192
    DOI 10.1016/j.jconrel.2018.11.029, PubMed 30529259
  20. González ML, Causada-Calo N, Santino JP, Dominguez-Valentin M, Ferro FA, Sammartino I, Kalfayan PG, Verzura MA, Piñero TA, Cajal AR, Pavicic W, Vaccaro C (2018)
    Universal determination of microsatellite instability using BAT26 as a single marker in an Argentine colorectal cancer cohort
    Fam Cancer, 17 (3), 395-402
    DOI 10.1007/s10689-017-0052-4, PubMed 29128931
  21. Gouravan S, Meza-Zepeda LA, Myklebost O, Stratford EW, Munthe E (2018)
    Preclinical Evaluation of Vemurafenib as Therapy for BRAFV600E Mutated Sarcomas
    Int J Mol Sci, 19 (4)
    DOI 10.3390/ijms19040969, PubMed 29570692
  22. Halushka MK, Fromm B, Peterson KJ, McCall MN (2018)
    Big Strides in Cellular MicroRNA Expression
    Trends Genet, 34 (3), 165-167
    DOI 10.1016/j.tig.2017.12.015, PubMed 29361313
  23. Ibrahim I, Dominguez-Valentin M, Segal B, Zeitouni A, da Silva SD (2018)
    Mitochondrial mutations associated with hearing and balance disorders
    Mutat Res, 810, 39-44
    DOI 10.1016/j.mrfmmm.2018.03.003, PubMed 29615272
  24. Jacobs B, Pfefferle A, Clement D, Berg-Larsen A, Saetersmoen ML, Lorenz S, Wiiger MT, Goodridge JP, Malmberg KJ (2018)
    Induction of the BIM Short Splice Variant Sensitizes Proliferating NK Cells to IL-15 Withdrawal
    J Immunol, 202 (3), 736-746
    DOI 10.4049/jimmunol.1801146, PubMed 30578306
  25. Kalanxhi E, Meltzer S, Schou JV, Larsen FO, Dueland S, Flatmark K, Jensen BV, Hole KH, Seierstad T, Redalen KR, Nielsen DL, Ree AH (2018)
    Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer
    Br J Cancer, 118 (10), 1322-1328
    DOI 10.1038/s41416-018-0085-y, PubMed 29695770
  26. Kim SJ, Huzarski T, Gronwald J, Singer CF, Møller P, Lynch HT, Armel S, Karlan BY, Foulkes WD, Neuhausen SL, Senter L, Eisen A, Eng C, Panchal S, Pal T, Olopade O, Zakalik D, Lubinski J, Narod SA, Kotsopoulos J, (2018)
    Prospective evaluation of body size and breast cancer risk among BRCA1 and BRCA2 mutation carriers
    Int J Epidemiol, 47 (3), 987-997
    DOI 10.1093/ije/dyy039, PubMed 29547931
  27. Kostas M, Haugsten EM, Zhen Y, Sørensen V, Szybowska P, Fiorito E, Lorenz S, Jones N, de Souza GA, Wiedlocha A, Wesche J (2018)
    Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
    Mol Cell Proteomics, 17 (5), 850-870
    DOI 10.1074/mcp.RA117.000538, PubMed 29371290
  28. Kotsopoulos J, Gronwald J, Karlan B, Rosen B, Huzarski T, Moller P, Lynch HT, Singer CF, Senter L, Neuhausen SL, Tung N, Eisen A, Foulkes WD, Ainsworth P, Sun P, Lubinski J, Narod SA, Hereditary Ovarian Cancer Clinical Study Group (2018)
    Age-specific ovarian cancer risks among women with a BRCA1 or BRCA2 mutation
    Gynecol Oncol, 150 (1), 85-91
    DOI 10.1016/j.ygyno.2018.05.011, PubMed 29793803
  29. Kotsopoulos J, Gronwald J, Karlan BY, Huzarski T, Tung N, Moller P, Armel S, Lynch HT, Senter L, Eisen A, Singer CF, Foulkes WD, Jacobson MR, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2018)
    Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers
    JAMA Oncol, 4 (8), 1059-1065
    DOI 10.1001/jamaoncol.2018.0211, PubMed 29710224
  30. Kresse SH, Namløs HM, Lorenz S, Berner JM, Myklebost O, Bjerkehagen B, Meza-Zepeda LA (2018)
    Evaluation of commercial DNA and RNA extraction methods for high-throughput sequencing of FFPE samples
    PLoS One, 13 (5), e0197456
    DOI 10.1371/journal.pone.0197456, PubMed 29771965
  31. Köger N, Paulsen L, López-Kostner F, Della Valle A, Vaccaro CA, Palmero EI, Alvarez K, Sarroca C, Neffa F, Kalfayan PG, Gonzalez ML, Rossi BM, Reis RM, Brieger A, Zeuzem S, Hinrichsen I, Dominguez-Valentin M, Plotz G (2018)
    Evaluation of MLH1 variants of unclear significance
    Genes Chromosomes Cancer, 57 (7), 350-358
    DOI 10.1002/gcc.22536, PubMed 29520894
  32. Løvf M, Zhao S, Axcrona U, Johannessen B, Bakken AC, Carm KT, Hoff AM, Myklebost O, Meza-Zepeda LA, Lie AK, Axcrona K, Lothe RA, Skotheim RI (2018)
    Multifocal Primary Prostate Cancer Exhibits High Degree of Genomic Heterogeneity
    Eur Urol, 75 (3), 498-505
    DOI 10.1016/j.eururo.2018.08.009, PubMed 30181068
  33. Mariathasan AB, Boye K, Giercksky KE, Brennhovd B, Gullestad HP, Emblemsvåg HL, Grøholt KK, Dueland S, Flatmark K, Larsen SG (2018)
    Beyond total mesorectal excision in locally advanced rectal cancer with organ or pelvic side-wall involvement
    Eur J Surg Oncol, 44 (8), 1226-1232
    DOI 10.1016/j.ejso.2018.03.029, PubMed 29691115
  34. Mavaddat N, Michailidou K, Dennis J, Lush M, Fachal L, Lee A, Tyrer JP, Chen TH, Wang Q, Bolla MK, Yang X, Adank MA, Ahearn T, Aittomäki K, Allen J, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Auer PL, Auvinen P, Barrdahl M, Beane Freeman LE, Beckmann MW et al. (2018)
    Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
    Am J Hum Genet, 104 (1), 21-34
    DOI 10.1016/j.ajhg.2018.11.002, PubMed 30554720
  35. Mikalsen SG, Mikalsen LTG, Sandvik JA, Aarnes EK, Fenne S, Flatmark K, Lyng H, Edin NFJ, Pettersen EO (2018)
    Low dose-rate irradiation with [3H]-labelled valine to selectively target hypoxic cells in a human colorectal cancer xenograft model
    Acta Oncol, 57 (9), 1216-1224
    DOI 10.1080/0284186X.2018.1457223, PubMed 29630428
  36. Møller P, Hovig E (2018)
    Retraction Note to: The BRCA2 variant c.68-7 T > A is associated with breast cancer
    Hered Cancer Clin Pract, 16, 10
    DOI 10.1186/s13053-018-0093-1, PubMed 29745381
  37. Namløs HM, Boye K, Mishkin SJ, Barøy T, Lorenz S, Bjerkehagen B, Stratford EW, Munthe E, Kudlow BA, Myklebost O, Meza-Zepeda LA (2018)
    Noninvasive Detection of ctDNA Reveals Intratumor Heterogeneity and Is Associated with Tumor Burden in Gastrointestinal Stromal Tumor
    Mol Cancer Ther, 17 (11), 2473-2480
    DOI 10.1158/1535-7163.MCT-18-0174, PubMed 30097488
  38. Nunes-Xavier CE, Mingo J, López JI, Pulido R (2018)
    The role of protein tyrosine phosphatases in prostate cancer biology
    Biochim Biophys Acta Mol Cell Res, 1866 (1), 102-113
    DOI 10.1016/j.bbamcr.2018.06.016, PubMed 30401533
  39. Prasmickaite L, Tenstad EM, Pettersen S, Jabeen S, Egeland EV, Nord S, Pandya A, Haugen MH, Kristensen VN, Børresen-Dale AL, Oslo Breast Cancer Research Consortium (OSBREAC), Engebråten O, Maelandsmo GM (2018)
    Basal-like breast cancer engages tumor-supportive macrophages via secreted factors induced by extracellular S100A4
    Mol Oncol, 12 (9), 1540-1558
    DOI 10.1002/1878-0261.12319, PubMed 29741811
  40. Prencipe M, Fabre A, Murphy TB, Vargyas E, O'Neill A, Bjartell A, Tasken KA, Grytli HH, Svindland A, Berge V, Eri LM, Gallagher W, Watson RW (2018)
    Role of serum response factor expression in prostate cancer biochemical recurrence
    Prostate, 78 (10), 724-730
    DOI 10.1002/pros.23516, PubMed 29608018
  41. Saeednejad Zanjani L, Madjd Z, Abolhasani M, Rasti A, Shariftabrizi A, Mehrazma M, Fodstad Ø, Asgari M (2018)
    Human telomerase reverse transcriptase protein expression predicts tumour aggressiveness and survival in patients with clear cell renal cell carcinoma
    Pathology, 51 (1), 21-31
    DOI 10.1016/j.pathol.2018.08.019, PubMed 30466948
  42. Seip K, Jørgensen K, Haselager MV, Albrecht M, Haugen MH, Egeland EV, Lucarelli P, Engebraaten O, Sauter T, Mælandsmo GM, Prasmickaite L (2018)
    Stroma-induced phenotypic plasticity offers phenotype-specific targeting to improve melanoma treatment
    Cancer Lett, 439, 1-13
    DOI 10.1016/j.canlet.2018.09.023, PubMed 30240588
  43. Spasojevic M, Mariathasan AB, Goscinski M, Thorgersen EB, Solbakken AM, Gullestad HP, Ryder T, Flatmark K, Larsen SG (2018)
    Vertical Rectus Abdominis Musculocutaneous Flap Repair Improves Perineal Wound Healing after Abdominoperineal Resection for Irradiated Locally Advanced Rectal Cancer
    Ann Surg Oncol, 25 (5), 1357-1365
    DOI 10.1245/s10434-018-6363-3, PubMed 29497909
  44. Tarver JE, Taylor RS, Puttick MN, Lloyd GT, Pett W, Fromm B, Schirrmeister BE, Pisani D, Peterson KJ, Donoghue PCJ (2018)
    Well-Annotated microRNAomes Do Not Evidence Pervasive miRNA Loss
    Genome Biol Evol, 10 (6), 1457-1470
    DOI 10.1093/gbe/evy096, PubMed 29788279
  45. Ten Broeke SW, van der Klift HM, Tops CMJ, Aretz S, Bernstein I, Buchanan DD, de la Chapelle A, Capella G, Clendenning M, Engel C, Gallinger S, Gomez Garcia E, Figueiredo JC, Haile R, Hampel HL, Hopper JL, Hoogerbrugge N, von Knebel Doeberitz M, Le Marchand L, Letteboer TGW, Jenkins MA, Lindblom A, Lindor NM, Mensenkamp AR, Møller P et al. (2018)
    Cancer Risks for PMS2-Associated Lynch Syndrome
    J Clin Oncol, 36 (29), 2961-2968
    DOI 10.1200/JCO.2018.78.4777, PubMed 30161022
  46. Vaccaro CA, López-Kostner F, Adriana DV, Palmero EI, Rossi BM, Antelo M, Solano A, Carraro DM, Forones NM, Bohorquez M, Lino-Silva LS, Buleje J, Spirandelli F, Abe-Sandes K, Nascimento I, Sullcahuaman Y, Sarroca C, Gonzalez ML, Herrando AI, Alvarez K, Neffa F, Galvão HC, Esperon P, Golubicki M, Cisterna D et al. (2018)
    From colorectal cancer pattern to the characterization of individuals at risk: Picture for genetic research in Latin America
    Int J Cancer, 145 (2), 318-326
    DOI 10.1002/ijc.31920, PubMed 30303536
  47. Vodák D, Lorenz S, Nakken S, Aasheim LB, Holte H, Bai B, Myklebost O, Meza-Zepeda LA, Hovig E (2018)
    Sample-Index Misassignment Impacts Tumour Exome Sequencing
    Sci Rep, 8 (1), 5307
    DOI 10.1038/s41598-018-23563-4, PubMed 29593270
  48. Westrøm S, Bønsdorff TB, Bruland ØS, Larsen RH (2018)
    Therapeutic Effect of α-Emitting 224Ra-Labeled Calcium Carbonate Microparticles in Mice with Intraperitoneal Ovarian Cancer
    Transl Oncol, 11 (2), 259-267
    DOI 10.1016/j.tranon.2017.12.011, PubMed 29413758
  49. Westrøm S, Malenge M, Jorstad IS, Napoli E, Bruland ØS, Bønsdorff TB, Larsen RH (2018)
    Ra-224 labeling of calcium carbonate microparticles for internal α-therapy: Preparation, stability, and biodistribution in mice
    J Labelled Comp Radiopharm, 61 (6), 472-486
    DOI 10.1002/jlcr.3610, PubMed 29380410
  50. Zhen Y, Haugsten EM, Singh SK, Wesche J (2018)
    Proximity Labeling by a Recombinant APEX2-FGF1 Fusion Protein Reveals Interaction of FGF1 with the Proteoglycans CD44 and CSPG4
    Biochemistry, 57 (26), 3807-3816
    DOI 10.1021/acs.biochem.8b00120, PubMed 29812912

Publications 2017

  1. Andersson Y, Haavardtun SI, Davidson B, Dørum A, Fleten KG, Fodstad Ø, Flatmark K (2017)
    MOC31PE immunotoxin - targeting peritoneal metastasis from epithelial ovarian cancer
    Oncotarget, 8 (37), 61800-61809
    DOI 10.18632/oncotarget.18694, PubMed 28977905
  2. Arstad C, Refinetti P, Kristensen AT, Giercksky KE, Ekstrøm PO (2017)
    Is detection of intraperitoneal exfoliated tumor cells after surgical resection of rectal cancer a prognostic factor of survival?
    BMC Cancer, 17 (1), 406
    DOI 10.1186/s12885-017-3365-7, PubMed 28592327
  3. Aure MR, Vitelli V, Jernström S, Kumar S, Krohn M, Due EU, Haukaas TH, Leivonen SK, Vollan HK, Lüders T, Rødland E, Vaske CJ, Zhao W, Møller EK, Nord S, Giskeødegård GF, Bathen TF, Caldas C, Tramm T, Alsner J, Overgaard J, Geisler J, Bukholm IR, Naume B, Schlichting E et al. (2017)
    Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome
    Breast Cancer Res, 19 (1), 44
    DOI 10.1186/s13058-017-0812-y, PubMed 28356166
  4. Bakke KM, Hole KH, Dueland S, Grøholt KK, Flatmark K, Ree AH, Seierstad T, Redalen KR (2017)
    Diffusion-weighted magnetic resonance imaging of rectal cancer: tumour volume and perfusion fraction predict chemoradiotherapy response and survival
    Acta Oncol, 56 (6), 813-818
    DOI 10.1080/0284186X.2017.1287951, PubMed 28464745
  5. Behjati S, Tarpey PS, Haase K, Ye H, Young MD, Alexandrov LB, Farndon SJ, Collord G, Wedge DC, Martincorena I, Cooke SL, Davies H, Mifsud W, Lidgren M, Martin S, Latimer C, Maddison M, Butler AP, Teague JW, Pillay N, Shlien A, McDermott U, Futreal PA, Baumhoer D, Zaikova O et al. (2017)
    Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma
    Nat Commun, 8, 15936
    DOI 10.1038/ncomms15936, PubMed 28643781
  6. Berg KCG, Eide PW, Eilertsen IA, Johannessen B, Bruun J, Danielsen SA, Bjørnslett M, Meza-Zepeda LA, Eknæs M, Lind GE, Myklebost O, Skotheim RI, Sveen A, Lothe RA (2017)
    Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies
    Mol Cancer, 16 (1), 116
    DOI 10.1186/s12943-017-0691-y, PubMed 28683746
  7. Braadland PR, Giskeødegård G, Sandsmark E, Bertilsson H, Euceda LR, Hansen AF, Guldvik IJ, Selnæs KM, Grytli HH, Katz B, Svindland A, Bathen TF, Eri LM, Nygård S, Berge V, Taskén KA, Tessem MB (2017)
    Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
    Br J Cancer, 117 (11), 1656-1664
    DOI 10.1038/bjc.2017.346, PubMed 28972967
  8. Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E et al. (2017)
    Interrogating open issues in cancer precision medicine with patient-derived xenografts
    Nat Rev Cancer, 17 (4), 254-268
    DOI 10.1038/nrc.2016.140, PubMed 28104906
  9. Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E et al. (2017)
    Interrogating open issues in cancer medicine with patient-derived xenografts
    Nat Rev Cancer, 17 (10), 632 (in press)
    DOI 10.1038/nrc.2017.85, PubMed 28912576
  10. Clancy T, Dannenfelser R, Troyanskaya O, Malmberg KJ, Hovig E, Kristensen V (2017)
    Bioinformatics Approaches to Profile the Tumor Microenvironment for Immunotherapeutic Discovery
    Curr Pharm Des, 23 (32), 4716-4725
    DOI 10.2174/1381612823666170710154936, PubMed 28699527
  11. Domanska D, Vodák D, Lund-Andersen C, Salvatore S, Hovig E, Sandve GK (2017)
    The rainfall plot: its motivation, characteristics and pitfalls
    BMC Bioinformatics, 18 (1), 264
    DOI 10.1186/s12859-017-1679-8, PubMed 28521741
  12. Egeland EV, Boye K, Park D, Synnestvedt M, Sauer T, Oslo Breast Cancer Consortium (OSBREAC), Naume B, Borgen E, Mælandsmo GM (2017)
    Prognostic significance of S100A4-expression and subcellular localization in early-stage breast cancer
    Breast Cancer Res Treat, 162 (1), 127-137
    DOI 10.1007/s10549-016-4096-1, PubMed 28058579
  13. Egger B, Bachmann L, Fromm B (2017)
    Atp8 is in the ground pattern of flatworm mitochondrial genomes
    BMC Genomics, 18 (1), 414
    DOI 10.1186/s12864-017-3807-2, PubMed 28549457
  14. Eide N, Faye RS, Høifødt HK, Sandvik L, Qvale GA, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2017)
    The Results of Stricter Inclusion Criteria in an Immunomagnetic Detection Study of Micrometastatic Cells in Bone Marrow of Uveal Melanoma Patients - Relevance for Dormancy
    Pathol Oncol Res, 25 (1), 255-262
    DOI 10.1007/s12253-017-0355-7, PubMed 29098521
  15. Engkvist ME, Stratford EW, Lorenz S, Meza-Zepeda LA, Myklebost O, Munthe E (2017)
    Analysis of the miR-34 family functions in breast cancer reveals annotation error of miR-34b
    Sci Rep, 7 (1), 9655
    DOI 10.1038/s41598-017-10189-1, PubMed 28848235
  16. Euceda LR, Haukaas TH, Giskeodegard GF, Vettukattil R, Engel J, Silwal-Pandit L, Lundgren S, Borgen E, Garred O, Postma G, Buydens LMC, Borresen-Dale AL, Engebraaten O, Bathen TF (2017)
    Evaluation of metabolomic changes during neoadjuvant chemotherapy combined with bevacizumab in breast cancer using MR spectroscopy
    Metabolomics, 13 (4), 37
    DOI 10.1007/s11306-017-1168-0
  17. Flem-Karlsen K, Tekle C, Andersson Y, Flatmark K, Fodstad Ø, Nunes-Xavier CE (2017)
    Immunoregulatory protein B7-H3 promotes growth and decreases sensitivity to therapy in metastatic melanoma cells
    Pigment Cell Melanoma Res, 30 (5), 467-476
    DOI 10.1111/pcmr.12599, PubMed 28513992
  18. Fromm B, Ovchinnikov V, Høye E, Bernal D, Hackenberg M, Marcilla A (2017)
    On the presence and immunoregulatory functions of extracellular microRNAs in the trematode Fasciola hepatica
    Parasite Immunol, 39 (2)
    DOI 10.1111/pim.12399, PubMed 27809346
  19. Frøysnes IS, Andersson Y, Larsen SG, Davidson B, Øien JT, Olsen KH, Giercksky KE, Julsrud L, Fodstad Ø, Dueland S, Flatmark K (2017)
    Novel Treatment with Intraperitoneal MOC31PE Immunotoxin in Colorectal Peritoneal Metastasis: Results From the ImmunoPeCa Phase 1 Trial
    Ann Surg Oncol, 24 (7), 1916-1922
    DOI 10.1245/s10434-017-5814-6, PubMed 28224367
  20. Graudenzi A, Cava C, Bertoli G, Fromm B, Flatmark K, Mauri G, Castiglioni I (2017)
    Pathway-based classification of breast cancer subtypes
    Front Biosci (Landmark Ed), 22 (10), 1697-1712
    DOI 10.2741/4566, PubMed 28410140
  21. Halldorsson S, Rohatgi N, Magnusdottir M, Choudhary KS, Gudjonsson T, Knutsen E, Barkovskaya A, Hilmarsdottir B, Perander M, Mælandsmo GM, Gudmundsson S, Rolfsson Ó (2017)
    Metabolic re-wiring of isogenic breast epithelial cell lines following epithelial to mesenchymal transition
    Cancer Lett, 396, 117-129
    DOI 10.1016/j.canlet.2017.03.019, PubMed 28323032
  22. Helland Å, Brustugun OT, Nakken S, Halvorsen AR, Dønnem T, Bremnes R, Busund LT, Sun J, Lorenz S, Solberg SK, Jørgensen LH, Vodak D, Myklebost O, Hovig E, Meza-Zepeda LA (2017)
    High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival
    Int J Cancer, 141 (1), 184-190
    DOI 10.1002/ijc.30726, PubMed 28387924
  23. Hilmarsdottir B, Briem E, Halldorsson S, Kricker J, Ingthorsson S, Gustafsdottir S, Mælandsmo GM, Magnusson MK, Gudjonsson T (2017)
    Inhibition of PTP1B disrupts cell-cell adhesion and induces anoikis in breast epithelial cells
    Cell Death Dis, 8 (5), e2769
    DOI 10.1038/cddis.2017.177, PubMed 28492548
  24. Hompland I, Bruland ØS, Hølmebakk T, Poulsen JP, Stoldt S, Hall KS, Boye K (2017)
    Prediction of long-term survival in patients with metastatic gastrointestinal stromal tumor: analysis of a large, single-institution cohort
    Acta Oncol, 56 (10), 1317-1323
    DOI 10.1080/0284186X.2017.1330555, PubMed 28557540
  25. Jernström S, Hongisto V, Leivonen SK, Due EU, Tadele DS, Edgren H, Kallioniemi O, Perälä M, Mælandsmo GM, Sahlberg KK (2017)
    Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment response
    Breast Cancer (Dove Med Press), 9, 185-198
    DOI 10.2147/BCTT.S115600, PubMed 28356768
  26. Jiao X, Aravidis C, Marikkannu R, Rantala J, Picelli S, Adamovic T, Liu T, Maguire P, Kremeyer B, Luo L, von Holst S, Kontham V, Thutkawkorapin J, Margolin S, Du Q, Lundin J, Michailidou K, Bolla MK, Wang Q, Dennis J, Lush M, Ambrosone CB, Andrulis IL, Anton-Culver H, Antonenkova NN et al. (2017)
    PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1
    Oncotarget, 8 (61), 102769-102782
    DOI 10.18632/oncotarget.21800, PubMed 29262523
  27. Kanduri C, Domanska D, Hovig E, Sandve GK (2017)
    Genome build information is an essential part of genomic track files
    Genome Biol, 18 (1), 175
    DOI 10.1186/s13059-017-1312-1, PubMed 28911336
  28. Kivinummi K, Urbanucci A, Leinonen K, Tammela TLJ, Annala M, Isaacs WB, Bova GS, Nykter M, Visakorpi T (2017)
    The expression of AURKA is androgen regulated in castration-resistant prostate cancer
    Sci Rep, 7 (1), 17978
    DOI 10.1038/s41598-017-18210-3, PubMed 29269934
  29. Kristian A, Holtedahl JE, Torheim T, Futsaether C, Hernes E, Engebraaten O, Mælandsmo GM, Malinen E (2017)
    Dynamic 2-Deoxy-2-[18F]Fluoro-D-Glucose Positron Emission Tomography for Chemotherapy Response Monitoring of Breast Cancer Xenografts
    Mol Imaging Biol, 19 (2), 271-279
    DOI 10.1007/s11307-016-0998-x, PubMed 27541026
  30. Landfors M, Johansen J, Aronsen JM, Vågbø CB, Doré LC, He C, Sjaastad I, Sætrom P, Fedorcsák P, Dahl JA, Aanes H, Fußer M, Klungland A (2017)
    Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation
    Cell Discov, 3, 17013
    DOI 10.1038/celldisc.2017.13, PubMed 28529766
  31. Lim S, Phillips JB, Madeira da Silva L, Zhou M, Fodstad O, Owen LB, Tan M (2017)
    Interplay between Immune Checkpoint Proteins and Cellular Metabolism
    Cancer Res, 77 (6), 1245-1249
    DOI 10.1158/0008-5472.CAN-16-1647, PubMed 28246276
  32. Lunde NN, Haugen MH, Bodin Larsen KB, Damgaard I, Pettersen SJ, Kasem R, Rut W, Drag M, Poreba M, Johansen HT, Solberg R (2017)
    Glycosylation is important for legumain localization and processing to active forms but not for cystatin E/M inhibitory functions
    Biochimie, 139, 27-37
    DOI 10.1016/j.biochi.2017.05.009, PubMed 28528272
  33. Meisal R, Rounge TB, Christiansen IK, Eieland AK, Worren MM, Molden TF, Kommedal Ø, Hovig E, Leegaard TM, Ambur OH (2017)
    HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization
    PLoS One, 12 (1), e0169074
    DOI 10.1371/journal.pone.0169074, PubMed 28045981
  34. Møller P, Hovig E (2017)
    The BRCA2 variant c.68-7 T>A is associated with breast cancer
    Hered Cancer Clin Pract, 15, 20 (Retracted)
    DOI 10.1186/s13053-017-0080-y, PubMed 29158857
  35. Møller P, Seppälä TT, Bernstein I, Holinski-Feder E, Sala P, Gareth Evans D, Lindblom A, Macrae F, Blanco I, Sijmons RH, Jeffries J, Vasen HFA, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen JT, Jenkins MA, Green K, Lalloo F, Sunde L, Mints M et al. (2017)
    Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database
    Gut, 67 (7), 1306-1316
    DOI 10.1136/gutjnl-2017-314057, PubMed 28754778
  36. Namløs HM, Zaikova O, Bjerkehagen B, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2017)
    Use of liquid biopsies to monitor disease progression in a sarcoma patient: a case report
    BMC Cancer, 17 (1), 29
    DOI 10.1186/s12885-016-2992-8, PubMed 28061772
  37. Nestvold J, Wang MY, Camilio KA, Zinöcker S, Tjelle TE, Lindberg A, Haug BE, Kvalheim G, Sveinbjørnsson B, Rekdal Ø (2017)
    Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model
    Oncoimmunology, 6 (8), e1338236
    DOI 10.1080/2162402X.2017.1338236, PubMed 28920000
  38. Nygaard V, Rødland EA, Hovig E (2017)
    Reply to Towfic and others' letter to the editor
    Biostatistics, 18 (3), 586-587
    DOI 10.1093/biostatistics/kxx001, PubMed 28334081
  39. Ovchinnikov VY, Mordvinov VA, Fromm B (2017)
    Extreme conservation of miRNA complements in opisthorchiids
    Parasitol Int, 66 (6), 773-776
    DOI 10.1016/j.parint.2017.09.006, PubMed 28916307
  40. Ree AH, Russnes HG, Heinrich D, Dueland S, Boye K, Nygaard V, Silwal-Pandit L, Østrup O, Hovig E, Nygaard V, Rødland EA, Nakken S, Øien JT, Johansen C, Bergheim IR, Skarpeteig V, Sathermugathevan M, Sauer T, Lund-Iversen M, Beiske K, Nasser S, Julsrud L, Reisse CH, Ruud EA, Flørenes VA et al. (2017)
    Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate
    ESMO Open, 2 (2), e000158
    DOI 10.1136/esmoopen-2017-000158, PubMed 28761742
  41. Refinetti P, Arstad C, Thilly WG, Morgenthaler S, Ekstrøm PO (2017)
    Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and cycling temperature capillary electrophoresis
    BMC Clin Pathol, 17, 6
    DOI 10.1186/s12907-017-0042-3, PubMed 28405177
  42. Rossi BM, Palmero EI, López-Kostner F, Sarroca C, Vaccaro CA, Spirandelli F, Ashton-Prolla P, Rodriguez Y, de Campos Reis Galvão H, Reis RM, Escremim de Paula A, Capochin Romagnolo LG, Alvarez K, Della Valle A, Neffa F, Kalfayan PG, Spirandelli E, Chialina S, Gutiérrez Angulo M, Castro-Mujica MDC, Sanchez de Monte J, Quispe R, da Silva SD, Rossi NT, Barletta-Carrillo C et al. (2017)
    A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America
    BMC Cancer, 17 (1), 623
    DOI 10.1186/s12885-017-3599-4, PubMed 28874130
  43. Rustad EH, Coward E, Skytøen ER, Misund K, Holien T, Standal T, Børset M, Beisvag V, Myklebost O, Meza-Zepeda LA, Dai HY, Sundan A, Waage A (2017)
    Monitoring multiple myeloma by quantification of recurrent mutations in serum
    Haematologica, 102 (7), 1266-1272
    DOI 10.3324/haematol.2016.160564, PubMed 28385781
  44. Saeednejad Zanjani L, Madjd Z, Abolhasani M, Andersson Y, Rasti A, Shariftabrizi A, Asgari M (2017)
    Cytoplasmic expression of CD133 stemness marker is associated with tumor aggressiveness in clear cell renal cell carcinoma
    Exp Mol Pathol, 103 (2), 218-228
    DOI 10.1016/j.yexmp.2017.10.001, PubMed 29050853
  45. Saldova R, Haakensen VD, Rødland E, Walsh I, Stöckmann H, Engebraaten O, Børresen-Dale AL, Rudd PM (2017)
    Serum N-glycome alterations in breast cancer during multimodal treatment and follow-up
    Mol Oncol, 11 (10), 1361-1379
    DOI 10.1002/1878-0261.12105, PubMed 28657165
  46. Seppälä T, Pylvänäinen K, Evans DG, Järvinen H, Renkonen-Sinisalo L, Bernstein I, Holinski-Feder E, Sala P, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Jenkins M, Genuardi M, Green K et al. (2017)
    Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report
    Hered Cancer Clin Pract, 15, 18
    DOI 10.1186/s13053-017-0078-5, PubMed 29046738
  47. Serguienko A, Hanes R, Grad I, Wang MY, Myklebost O, Munthe E (2017)
    PP2A Regulatory Subunit B55γ is a Gatekeeper of Osteoblast Maturation and Lineage Maintenance
    Stem Cells Dev, 26 (19), 1375-1383
    DOI 10.1089/scd.2017.0129, PubMed 28805158
  48. Simovski B, Vodák D, Gundersen S, Domanska D, Azab A, Holden L, Holden M, Grytten I, Rand K, Drabløs F, Johansen M, Mora A, Lund-Andersen C, Fromm B, Eskeland R, Gabrielsen OS, Ferkingstad E, Nakken S, Bengtsen M, Nederbragt AJ, Thorarensen HS, Akse JA, Glad I, Hovig E, Sandve GK (2017)
    GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome
    Gigascience, 6 (7), 1-12
    DOI 10.1093/gigascience/gix032, PubMed 28459977
  49. Sveen A, Johannessen B, Tengs T, Danielsen SA, Eilertsen IA, Lind GE, Berg KCG, Leithe E, Meza-Zepeda LA, Domingo E, Myklebost O, Kerr D, Tomlinson I, Nesbakken A, Skotheim RI, Lothe RA (2017)
    Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1
    Genome Med, 9 (1), 46
    DOI 10.1186/s13073-017-0434-0, PubMed 28539123
  50. Sveinbjørnsson B, Camilio KA, Haug BE, Rekdal Ø (2017)
    LTX-315: a first-in-class oncolytic peptide that reprograms the tumor microenvironment
    Future Med Chem, 9 (12), 1339-1344
    DOI 10.4155/fmc-2017-0088, PubMed 28490192
  51. Umu SU, Langseth H, Bucher-Johannessen C, Fromm B, Keller A, Meese E, Lauritzen M, Leithaug M, Lyle R, Rounge TB (2017)
    A comprehensive profile of circulating RNAs in human serum
    RNA Biol, 15 (2), 242-250
    DOI 10.1080/15476286.2017.1403003, PubMed 29219730
  52. Urbanucci A, Barfeld SJ, Kytölä V, Itkonen HM, Coleman IM, Vodák D, Sjöblom L, Sheng X, Tolonen T, Minner S, Burdelski C, Kivinummi KK, Kohvakka A, Kregel S, Takhar M, Alshalalfa M, Davicioni E, Erho N, Lloyd P, Karnes RJ, Ross AE, Schaeffer EM, Vander Griend DJ, Knapp S, Corey E et al. (2017)
    Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer
    Cell Rep, 19 (10), 2045-2059
    DOI 10.1016/j.celrep.2017.05.049, PubMed 28591577
  53. Voisset E, Moravcsik E, Stratford EW, Jaye A, Palgrave CJ, Hills RK, Salomoni P, Kogan SC, Solomon E, Grimwade D (2017)
    Pml nuclear body disruption cooperates in APL pathogenesis and impairs DNA damage repair pathways in mice
    Blood, 131 (6), 636-648
    DOI 10.1182/blood-2017-07-794784, PubMed 29191918
  54. Wang MY, Nestvold J, Rekdal Ø, Kvalheim G, Fodstad Ø (2017)
    A novel rat fibrosarcoma cell line from transformed bone marrow-derived mesenchymal stem cells with maintained in vitro and in vivo stemness properties
    Exp Cell Res, 352 (2), 218-224
    DOI 10.1016/j.yexcr.2017.02.005, PubMed 28189639
  55. Westrøm S, Generalov R, Bønsdorff TB, Larsen RH (2017)
    Preparation of 212Pb-labeled monoclonal antibody using a novel 224Ra-based generator solution
    Nucl Med Biol, 51, 1-9
    DOI 10.1016/j.nucmedbio.2017.04.005, PubMed 28486098
  56. Zanjani LS, Madjd Z, Abolhasani M, Rasti A, Fodstad O, Andersson Y, Asgari M (2017)
    Increased expression of CD44 is associated with more aggressive behavior in clear cell renal cell carcinoma
    Biomark Med, 12 (1), 45-61
    DOI 10.2217/bmm-2017-0142, PubMed 29243496
  57. Østrup O, Dagenborg VJ, Rødland EA, Skarpeteig V, Silwal-Pandit L, Grzyb K, Berstad AE, Fretland ÅA, Mælandsmo GM, Børresen-Dale AL, Ree AH, Edwin B, Nygaard V, Flatmark K (2017)
    Molecular signatures reflecting microenvironmental metabolism and chemotherapy-induced immunogenic cell death in colorectal liver metastases
    Oncotarget, 8 (44), 76290-76304
    DOI 10.18632/oncotarget.19350, PubMed 29100312
  58. Øverbye A, Holsæter AM, Markus F, Škalko-Basnet N, Iversen TG, Torgersen ML, Sønstevold T, Engebraaten O, Flatmark K, Mælandsmo GM, Skotland T, Sandvig K (2017)
    Ceramide-containing liposomes with doxorubicin: time and cell-dependent effect of C6 and C12 ceramide
    Oncotarget, 8 (44), 76921-76934
    DOI 10.18632/oncotarget.20217, PubMed 29100358

Publications 2016

  1. Alonso A, Nunes-Xavier CE, Bayón Y, Pulido R (2016)
    The Extended Family of Protein Tyrosine Phosphatases
    Methods Mol Biol, 1447, 1-23
    DOI 10.1007/978-1-4939-3746-2_1, PubMed 27514797
  2. Alver TN, Lavelle TJ, Longva AS, Øy GF, Hovig E, Bøe SL (2016)
    MITF depletion elevates expression levels of ERBB3 receptor and its cognate ligand NRG1-beta in melanoma
    Oncotarget, 7 (34), 55128-55140
    DOI 10.18632/oncotarget.10422, PubMed 27391157
  3. Arstad C, Refinetti P, Warren D, Giercksky KE, Ekstrøm PO (2016)
    Scanning the mitochondrial genome for mutations by cycling temperature capillary electrophoresis
    Mitochondrial DNA A DNA Mapp Seq Anal, 29 (1), 19-30
    DOI 10.1080/24701394.2016.1233532, PubMed 27728990
  4. Bachmann L, Fromm B, Patella de Azambuja L, Boeger WA (2016)
    The mitochondrial genome of the egg-laying flatworm Aglaiogyrodactylus forficulatus (Platyhelminthes: Monogenoidea)
    Parasit Vectors, 9 (1), 285
    DOI 10.1186/s13071-016-1586-2, PubMed 27188228
  5. Ballinger ML, Goode DL, Ray-Coquard I, James PA, Mitchell G, Niedermayr E, Puri A, Schiffman JD, Dite GS, Cipponi A, Maki RG, Brohl AS, Myklebost O, Stratford EW, Lorenz S, Ahn SM, Ahn JH, Kim JE, Shanley S, Beshay V, Randall RL, Judson I, Seddon B, Campbell IG, Young MA et al. (2016)
    Monogenic and polygenic determinants of sarcoma risk: an international genetic study
    Lancet Oncol, 17 (9), 1261-71
    DOI 10.1016/S1470-2045(16)30147-4, PubMed 27498913
  6. Barøy T, Chilamakuri CS, Lorenz S, Sun J, Bruland ØS, Myklebost O, Meza-Zepeda LA (2016)
    Genome Analysis of Osteosarcoma Progression Samples Identifies FGFR1 Overexpression as a Potential Treatment Target and CHM as a Candidate Tumor Suppressor Gene
    PLoS One, 11 (9), e0163859
    DOI 10.1371/journal.pone.0163859, PubMed 27685995
  7. Björklund AT, Clancy T, Goodridge JP, Béziat V, Schaffer M, Hovig E, Ljunggren HG, Ljungman PT, Malmberg KJ (2016)
    Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
    J Immunol, 196 (3), 1400-11
    DOI 10.4049/jimmunol.1501434, PubMed 26746188
  8. Boye K, Jacob H, Frikstad KA, Nesland JM, Maelandsmo GM, Dahl O, Nesbakken A, Flatmark K (2016)
    Prognostic significance of S100A4 expression in stage II and III colorectal cancer: results from a population-based series and a randomized phase III study on adjuvant chemotherapy
    Cancer Med, 5 (8), 1840-9
    DOI 10.1002/cam4.766, PubMed 27273130
  9. Braadland PR, Grytli HH, Ramberg H, Katz B, Kellman R, Gauthier-Landry L, Fazli L, Krobert KA, Wang W, Levy FO, Bjartell A, Berge V, Rennie PS, Mellgren G, Mælandsmo GM, Svindland A, Barbier O, Taskén KA (2016)
    Low β₂-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism
    Oncotarget, 7 (2), 1878-94
    DOI 10.18632/oncotarget.6479, PubMed 26646591
  10. Børnich C, Grytten I, Hovig E, Paulsen J, Čech M, Sandve GK (2016)
    Galaxy Portal: interacting with the galaxy platform through mobile devices
    Bioinformatics, 32 (11), 1743-5
    DOI 10.1093/bioinformatics/btw042, PubMed 26819474
  11. Clancy T, Hovig E (2016)
    Profiling networks of distinct immune-cells in tumors
    BMC Bioinformatics, 17 (1), 263
    DOI 10.1186/s12859-016-1141-3, PubMed 27377892
  12. DA Silva FC, Wernhoff P, Dominguez-Barrera C, Dominguez-Valentin M (2016)
    Update on Hereditary Colorectal Cancer
    Anticancer Res, 36 (9), 4399-405
    DOI 10.21873/anticanres.10983, PubMed 27630275
  13. Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A (2016)
    Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
    Nature, 537 (7621), 548-552
    DOI 10.1038/nature19360, PubMed 27626377
  14. Di Stefano M, Paulsen J, Lien TG, Hovig E, Micheletti C (2016)
    Hi-C-constrained physical models of human chromosomes recover functionally-related properties of genome organization
    Sci Rep, 6, 35985
    DOI 10.1038/srep35985, PubMed 27786255
  15. Dominguez-Valentin M, Wernhoff P, Cajal AR, Kalfayan PG, Piñero TA, Gonzalez ML, Ferro A, Sammartino I, Causada Calo NS, Vaccaro CA (2016)
    MLH1 Ile219Val Polymorphism in Argentinean Families with Suspected Lynch Syndrome
    Front Oncol, 6, 189
    DOI 10.3389/fonc.2016.00189, PubMed 27606285
  16. Dueland S, Ree AH, Grøholt KK, Saelen MG, Folkvord S, Hole KH, Seierstad T, Larsen SG, Giercksky KE, Wiig JN, Boye K, Flatmark K (2016)
    Oxaliplatin-containing Preoperative Therapy in Locally Advanced Rectal Cancer: Local Response, Toxicity and Long-term Outcome
    Clin Oncol (R Coll Radiol), 28 (8), 532-9
    DOI 10.1016/j.clon.2016.01.014, PubMed 26888115
  17. Egeland EV, Flatmark K, Nesland JM, Flørenes VA, Mælandsmo GM, Boye K (2016)
    Expression and clinical significance of Wee1 in colorectal cancer
    Tumour Biol, 37 (9), 12133-12140
    DOI 10.1007/s13277-016-5081-3, PubMed 27220319
  18. Errarte P, Guarch R, Pulido R, Blanco L, Nunes-Xavier CE, Beitia M, Gil J, Angulo JC, López JI, Larrinaga G (2016)
    The Expression of Fibroblast Activation Protein in Clear Cell Renal Cell Carcinomas Is Associated with Synchronous Lymph Node Metastases
    PLoS One, 11 (12), e0169105
    DOI 10.1371/journal.pone.0169105, PubMed 28033421
  19. Evans DG, Harkness EF, Howell A, Wilson M, Hurley E, Holmen MM, Tharmaratnam KU, Hagen AI, Lim Y, Maxwell AJ, Moller P (2016)
    Intensive breast screening in BRCA2 mutation carriers is associated with reduced breast cancer specific and all cause mortality
    Hered Cancer Clin Pract, 14, 8
    DOI 10.1186/s13053-016-0048-3, PubMed 27087880
  20. Evensen L, Johansen PL, Koster G, Zhu K, Herfindal L, Speth M, Fenaroli F, Hildahl J, Bagherifam S, Tulotta C, Prasmickaite L, Mælandsmo GM, Snaar-Jagalska E, Griffiths G (2016)
    Zebrafish as a model system for characterization of nanoparticles against cancer
    Nanoscale, 8 (2), 862-77
    DOI 10.1039/c5nr07289a, PubMed 26648525
  21. Flatmark K, Høye E, Fromm B (2016)
    microRNAs as cancer biomarkers
    Scand J Clin Lab Invest Suppl, 245, S80-3
    DOI 10.1080/00365513.2016.1210330, PubMed 27542003
  22. Flatmark K, Saelen MG, Hole KH, Abrahamsen TW, Fleten KG, Hektoen HH, Redalen KR, Seierstad T, Dueland S, Ree AH (2016)
    Individual tumor volume responses to short-course oxaliplatin-containing induction chemotherapy in locally advanced rectal cancer - Targeting the tumor for radiation sensitivity?
    Radiother Oncol, 119 (3), 505-11
    DOI 10.1016/j.radonc.2016.02.020, PubMed 26968754
  23. Fleten KG, Bakke KM, Mælandsmo GM, Abildgaard A, Redalen KR, Flatmark K (2016)
    Use of non-invasive imaging to monitor response to aflibercept treatment in murine models of colorectal cancer liver metastases
    Clin Exp Metastasis, 34 (1), 51-62
    DOI 10.1007/s10585-016-9829-3, PubMed 27812769
  24. Fleten KG, Flørenes VA, Prasmickaite L, Hill O, Sykora J, Mælandsmo GM, Engesæter B (2016)
    hvTRA, a novel TRAIL receptor agonist, induces apoptosis and sustained growth retardation in melanoma
    Cell Death Discov, 2, 16081
    DOI 10.1038/cddiscovery.2016.81, PubMed 28028438
  25. Frøysnes IS, Larsen SG, Spasojevic M, Dueland S, Flatmark K (2016)
    Complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastasis in Norway: Prognostic factors and oncologic outcome in a national patient cohort
    J Surg Oncol, 114 (2), 222-7
    DOI 10.1002/jso.24290, PubMed 27173150
  26. Halvorsen AR, Silwal-Pandit L, Meza-Zepeda LA, Vodak D, Vu P, Sagerup C, Hovig E, Myklebost O, Børresen-Dale AL, Brustugun OT, Helland Å (2016)
    TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients
    Front Genet, 7, 85
    DOI 10.3389/fgene.2016.00085, PubMed 27242894
  27. Hanes R, Grad I, Lorenz S, Stratford EW, Munthe E, Reddy CC, Meza-Zepeda LA, Myklebost O (2016)
    Preclinical evaluation of potential therapeutic targets in dedifferentiated liposarcoma
    Oncotarget, 7 (34), 54583-54595
    DOI 10.18632/oncotarget.10518, PubMed 27409346
  28. Haugvik SP, Vodák D, Haugom L, Hovig E, Gladhaug IP, Heim S, Micci F (2016)
    Transcriptomic Profiling of Tumor Aggressiveness in Sporadic Nonfunctioning Pancreatic Neuroendocrine Neoplasms
    Pancreas, 45 (8), 1196-203
    DOI 10.1097/MPA.0000000000000610, PubMed 26918873
  29. Hetland G, Eide DM, Tangen JM, Haugen MH, Mirlashari MR, Paulsen JE (2016)
    The Agaricus blazei-Based Mushroom Extract, Andosan™, Protects against Intestinal Tumorigenesis in the A/J Min/+ Mouse
    PLoS One, 11 (12), e0167754
    DOI 10.1371/journal.pone.0167754, PubMed 28002446
  30. Hompland I, Bruland ØS, Ubhayasekhera K, Bergquist J, Boye K (2016)
    Clinical implications of repeated drug monitoring of imatinib in patients with metastatic gastrointestinal stromal tumour
    Clin Sarcoma Res, 6, 21
    DOI 10.1186/s13569-016-0062-2, PubMed 27999655
  31. Haakensen VD, Nygaard V, Greger L, Aure MR, Fromm B, Bukholm IR, Lüders T, Chin SF, Git A, Caldas C, Kristensen VN, Brazma A, Børresen-Dale AL, Hovig E, Helland Å (2016)
    Subtype-specific micro-RNA expression signatures in breast cancer progression
    Int J Cancer, 139 (5), 1117-28
    DOI 10.1002/ijc.30142, PubMed 27082076
  32. Itkonen HM, Gorad SS, Duveau DY, Martin SE, Barkovskaya A, Bathen TF, Moestue SA, Mills IG (2016)
    Inhibition of O-GlcNAc transferase activity reprograms prostate cancer cell metabolism
    Oncotarget, 7 (11), 12464-76
    DOI 10.18632/oncotarget.7039, PubMed 26824323
  33. Jonsson M, Ragnum HB, Julin CH, Yeramian A, Clancy T, Frikstad KM, Seierstad T, Stokke T, Matias-Guiu X, Ree AH, Flatmark K, Lyng H (2016)
    Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
    Br J Cancer, 115 (8), 929-939
    DOI 10.1038/bjc.2016.278, PubMed 27599042
  34. Joshi S, Schjølberg AR, Ekstrøm PO, De Angelis PM, Zucknick M, Andersen SN, Clausen OP (2016)
    Tp53/p53 status in keratoacanthomas
    J Cutan Pathol, 43 (7), 571-8
    DOI 10.1111/cup.12713, PubMed 27020606
  35. Kalanxhi E, Hektoen HH, Meltzer S, Dueland S, Flatmark K, Ree AH (2016)
    Circulating proteins in response to combined-modality therapy in rectal cancer identified by antibody array screening
    BMC Cancer, 16, 536
    DOI 10.1186/s12885-016-2601-x, PubMed 27461255
  36. Kalanxhi E, Risberg K, Barua IS, Dueland S, Waagene S, Andersen SN, Pettersen SJ, Lindvall JM, Redalen KR, Flatmark K, Ree AH (2016)
    Induction of Apoptosis in Intestinal Toxicity to a Histone Deacetylase Inhibitor in a Phase I Study with Pelvic Radiotherapy
    Cancer Res Treat, 49 (2), 374-386
    DOI 10.4143/crt.2016.080, PubMed 27488871
  37. Kim E, Kim J, Maelandsmo GM, Johansen B, Moestue SA (2016)
    Anti-angiogenic therapy affects the relationship between tumor vascular structure and function: A correlation study between micro-computed tomography angiography and dynamic contrast enhanced MRI
    Magn Reson Med, 78 (4), 1513-1522
    DOI 10.1002/mrm.26547, PubMed 27888545
  38. Kim E, Tunset HM, Cebulla J, Vettukattil R, Helgesen H, Feuerherm AJ, Engebråten O, Mælandsmo GM, Johansen B, Moestue SA (2016)
    Anti-vascular effects of the cytosolic phospholipase A2 inhibitor AVX235 in a patient-derived basal-like breast cancer model
    BMC Cancer, 16, 191
    DOI 10.1186/s12885-016-2225-1, PubMed 26951085
  39. Kongsgaard A, Boye K, Fodstad Ø, Juell S, Jørgensen LH, Solberg S, Helland Å, Brustugun OT, Mælandsmo GM (2016)
    Detection of disseminated tumor cells in lymph nodes from patients with early stage non-small cell lung cancer
    Diagn Pathol, 11 (1), 50
    DOI 10.1186/s13000-016-0504-4, PubMed 27316334
  40. Kotsopoulos J, Huzarski T, Gronwald J, Moller P, Lynch HT, Neuhausen SL, Senter L, Demsky R, Foulkes WD, Eng C, Karlan B, Tung N, Singer CF, Sun P, Lubinski J, Narod SA (2016)
    Hormone replacement therapy after menopause and risk of breast cancer in BRCA1 mutation carriers: a case-control study
    Breast Cancer Res Treat, 155 (2), 365-73
    DOI 10.1007/s10549-016-3685-3, PubMed 26780555
  41. Kotsopoulos J, Huzarski T, Gronwald J, Singer CF, Moller P, Lynch HT, Armel S, Karlan B, Foulkes WD, Neuhausen SL, Senter L, Tung N, Weitzel JN, Eisen A, Metcalfe K, Eng C, Pal T, Evans G, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2016)
    Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
    J Natl Cancer Inst, 109 (1)
    DOI 10.1093/jnci/djw177, PubMed 27601060
  42. Landfors M, Nakken S, Fusser M, Dahl JA, Klungland A, Fedorcsak P (2016)
    Sequencing of FTO and ALKBH5 in men undergoing infertility work-up identifies an infertility-associated variant and two missense mutations
    Fertil Steril, 105 (5), 1170-1179.e5
    DOI 10.1016/j.fertnstert.2016.01.002, PubMed 26820768
  43. Lim S, Liu H, Madeira da Silva L, Arora R, Liu Z, Phillips JB, Schmitt DC, Vu T, McClellan S, Lin Y, Lin W, Piazza GA, Fodstad O, Tan M (2016)
    Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1α
    Cancer Res, 76 (8), 2231-42
    DOI 10.1158/0008-5472.CAN-15-1538, PubMed 27197253
  44. Lindstad T, Qu S, Sikkeland J, Jin Y, Kristian A, Mælandsmo GM, Collas P, Saatcioglu F (2016)
    STAMP2 is required for human adipose-derived stem cell differentiation and adipocyte-facilitated prostate cancer growth in vivo
    Oncotarget, 8 (54), 91817-91827
    DOI 10.18632/oncotarget.11131, PubMed 29190878
  45. Lorenz S, Barøy T, Sun J, Nome T, Vodák D, Bryne JC, Håkelien AM, Fernandez-Cuesta L, Möhlendick B, Rieder H, Szuhai K, Zaikova O, Ahlquist TC, Thomassen GO, Skotheim RI, Lothe RA, Tarpey PS, Campbell P, Flanagan A, Myklebost O, Meza-Zepeda LA (2016)
    Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations
    Oncotarget, 7 (5), 5273-88
    DOI 10.18632/oncotarget.6567, PubMed 26672768
  46. Meltzer S, Kalanxhi E, Hektoen HH, Dueland S, Flatmark K, Redalen KR, Ree AH (2016)
    Systemic release of osteoprotegerin during oxaliplatin-containing induction chemotherapy and favorable systemic outcome of sequential radiotherapy in rectal cancer
    Oncotarget, 7 (23), 34907-17
    DOI 10.18632/oncotarget.8995, PubMed 27145458
  47. Moen LV, Ramberg H, Zhao S, Grytli HH, Sveen A, Berge V, Skotheim RI, Taskén KA, Skålhegg BS (2016)
    Observed correlation between the expression levels of catalytic subunit, Cβ2, of cyclic adenosine monophosphate-dependent protein kinase and prostate cancer aggressiveness
    Urol Oncol, 35 (3), 111.e1-111.e8
    DOI 10.1016/j.urolonc.2016.10.002, PubMed 27838142
  48. Munthe E, Riss PJ, Saga TA, Haraldsen I, Grad I, Bogsrud TV, Bach-Gansmo T (2016)
    FDG-based quantitative comparison of glucose metabolism in vitro, exemplified by a head-to-head comparison between a triple-negative breast cancer cell line and a non-malignant foetal cell line
    Clin Physiol Funct Imaging, 38 (1), 34-37
    DOI 10.1111/cpf.12378, PubMed 27297457
  49. Møller P, Seppälä T, Bernstein I, Holinski-Feder E, Sala P, Evans DG, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Jenkins M, Green K, Lalloo F, Sunde L, Mints M et al. (2016)
    Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database
    Gut, 66 (9), 1657-1664
    DOI 10.1136/gutjnl-2016-311403, PubMed 27261338
  50. Nunes-Xavier CE, Karlsen KF, Tekle C, Pedersen C, Øyjord T, Hongisto V, Nesland JM, Tan M, Sahlberg KK, Fodstad Ø (2016)
    Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors
    Oncotarget, 7 (6), 6891-901
    DOI 10.18632/oncotarget.6902, PubMed 26771843
  51. Nunes-Xavier CE, Pulido R (2016)
    Global RT-PCR and RT-qPCR Analysis of the mRNA Expression of the Human PTPome
    Methods Mol Biol, 1447, 25-37
    DOI 10.1007/978-1-4939-3746-2_2, PubMed 27514798
  52. Ramalho-Carvalho J, Fromm B, Henrique R, Jerónimo C (2016)
    Deciphering the function of non-coding RNAs in prostate cancer
    Cancer Metastasis Rev, 35 (2), 235-62
    DOI 10.1007/s10555-016-9628-y, PubMed 27221068
  53. Ramberg H, Grytli HH, Nygård S, Wang W, Ögren O, Zhao S, Løvf M, Katz B, Skotheim RI, Bjartell A, Eri LM, Berge V, Svindland A, Taskén KA (2016)
    PBX3 is a putative biomarker of aggressive prostate cancer
    Int J Cancer, 139 (8), 1810-20
    DOI 10.1002/ijc.30220, PubMed 27273830
  54. Refinetti P, Morgenthaler S, Ekstrøm PO (2016)
    Cycling temperature capillary electrophoresis: A quantitative, fast and inexpensive method to detect mutations in mixed populations of human mitochondrial DNA
    Mitochondrion, 29, 65-74
    DOI 10.1016/j.mito.2016.04.006, PubMed 27166160
  55. Safavi S, Järnum S, Vannas C, Udhane S, Jonasson E, Tomic TT, Grundevik P, Fagman H, Hansson M, Kalender Z, Jauhiainen A, Dolatabadi S, Stratford EW, Myklebost O, Eriksson M, Stenman G, Schneider-Stock R, Ståhlberg A, Åman P (2016)
    HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in vivo
    Oncotarget, 7 (1), 433-45
    DOI 10.18632/oncotarget.6336, PubMed 26595521
  56. Sandhu V, Wedge DC, Bowitz Lothe IM, Labori KJ, Dentro SC, Buanes T, Skrede ML, Dalsgaard AM, Munthe E, Myklebost O, Lingjærde OC, Børresen-Dale AL, Ikdahl T, Van Loo P, Nord S, Kure EH (2016)
    The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma
    Cancer Res, 76 (17), 5092-102
    DOI 10.1158/0008-5472.CAN-16-0658, PubMed 27488532
  57. Seip K, Fleten KG, Barkovskaya A, Nygaard V, Haugen MH, Engesæter BØ, Mælandsmo GM, Prasmickaite L (2016)
    Fibroblast-induced switching to the mesenchymal-like phenotype and PI3K/mTOR signaling protects melanoma cells from BRAF inhibitors
    Oncotarget, 7 (15), 19997-20015
    DOI 10.18632/oncotarget.7671, PubMed 26918352
  58. Späth F, Andersson U, Dahlin AM, Langseth H, Hovig E, Johannesen TB, Grankvist K, Björkblom B, Wibom C, Melin B (2016)
    Pre-diagnostic serum levels of EGFR and ErbB2 and genetic glioma risk variants: a nested case-control study
    Tumour Biol, 37 (8), 11065-72
    DOI 10.1007/s13277-015-4742-y, PubMed 26906551
  59. Thorgersen EB, Goscinski MA, Spasojevic M, Solbakken AM, Mariathasan AB, Boye K, Larsen SG, Flatmark K (2016)
    Deep Pelvic Surgical Site Infection After Radiotherapy and Surgery for Locally Advanced Rectal Cancer
    Ann Surg Oncol, 24 (3), 721-728
    DOI 10.1245/s10434-016-5621-5, PubMed 27766561
  60. Vaccaro CA, Sarroca C, Rossi B, Lopez-Kostner F, Dominguez M, Calo NC, Cutait R, Valle AD, Nuñez L, Neffa F, Alvarez K, Gonzalez ML, Kalfayan P, Lynch HT, Church J (2016)
    Lynch syndrome in South America: past, present and future
    Fam Cancer, 15 (3), 437-45
    DOI 10.1007/s10689-016-9903-7, PubMed 27007491
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    VOLIN and KJON-Two novel hyperdiploid myeloma cell lines
    Genes Chromosomes Cancer, 55 (11), 890-901
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  62. Westrøm S, Bønsdorff TB, Abbas N, Bruland ØS, Jonasdottir TJ, Mælandsmo GM, Larsen RH (2016)
    Evaluation of CD146 as Target for Radioimmunotherapy against Osteosarcoma
    PLoS One, 11 (10), e0165382
    DOI 10.1371/journal.pone.0165382, PubMed 27776176
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    The microRNA toolkit of insects
    Sci Rep, 6, 37736
    DOI 10.1038/srep37736, PubMed 27883064

Publications 2015

  1. Alioto TS, Buchhalter I, Derdak S, Hutter B, Eldridge MD, Hovig E, Heisler LE, Beck TA, Simpson JT, Tonon L, Sertier AS, Patch AM, Jäger N, Ginsbach P, Drews R, Paramasivam N, Kabbe R, Chotewutmontri S, Diessl N, Previti C, Schmidt S, Brors B, Feuerbach L, Heinold M, Gröbner S et al. (2015)
    A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
    Nat Commun, 6, 10001
    DOI 10.1038/ncomms10001, PubMed 26647970
  2. Almåsbak H, Walseng E, Kristian A, Myhre MR, Suso EM, Munthe LA, Andersen JT, Wang MY, Kvalheim G, Gaudernack G, Kyte JA (2015)
    Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model
    Gene Ther, 22 (5), 391-403
    DOI 10.1038/gt.2015.4, PubMed 25652098
  3. Andersson Y, Engebraaten O, Juell S, Aamdal S, Brunsvig P, Fodstad Ø, Dueland S (2015)
    Phase I trial of EpCAM-targeting immunotoxin MOC31PE, alone and in combination with cyclosporin
    Br J Cancer, 113 (11), 1548-55
    DOI 10.1038/bjc.2015.380, PubMed 26554649
  4. Aure MR, Jernström S, Krohn M, Vollan HK, Due EU, Rødland E, Kåresen R, Oslo Breast Cancer Research Consortium (OSBREAC), Ram P, Lu Y, Mills GB, Sahlberg KK, Børresen-Dale AL, Lingjærde OC, Kristensen VN (2015)
    Integrated analysis reveals microRNA networks coordinately expressed with key proteins in breast cancer
    Genome Med, 7 (1), 21
    DOI 10.1186/s13073-015-0135-5, PubMed 25873999
  5. Bengtsen M, Klepper K, Gundersen S, Cuervo I, Drabløs F, Hovig E, Sandve GK, Gabrielsen OS, Eskeland R (2015)
    c-Myb Binding Sites in Haematopoietic Chromatin Landscapes
    PLoS One, 10 (7), e0133280
    DOI 10.1371/journal.pone.0133280, PubMed 26208222
  6. Bettum IJ, Gorad SS, Barkovskaya A, Pettersen S, Moestue SA, Vasiliauskaite K, Tenstad E, Øyjord T, Risa Ø, Nygaard V, Mælandsmo GM, Prasmickaite L (2015)
    Metabolic reprogramming supports the invasive phenotype in malignant melanoma
    Cancer Lett, 366 (1), 71-83
    DOI 10.1016/j.canlet.2015.06.006, PubMed 26095603
  7. Braadland PR, Ramberg H, Grytli HH, Taskén KA (2015)
    β-Adrenergic Receptor Signaling in Prostate Cancer
    Front Oncol, 4, 375
    DOI 10.3389/fonc.2014.00375, PubMed 25629002
  8. Christiansen IK, Sandve GK, Schmitz M, Dürst M, Hovig E (2015)
    Transcriptionally active regions are the preferred targets for chromosomal HPV integration in cervical carcinogenesis
    PLoS One, 10 (3), e0119566
    DOI 10.1371/journal.pone.0119566, PubMed 25793388
  9. Chymkowitch P, Nguéa AP, Aanes H, Koehler CJ, Thiede B, Lorenz S, Meza-Zepeda LA, Klungland A, Enserink JM (2015)
    Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes
    Genome Res, 25 (6), 897-906
    DOI 10.1101/gr.185793.114, PubMed 25800674
  10. Egeland EV, Boye K, Pettersen SJ, Haugen MH, Øyjord T, Malerød L, Flatmark K, Mælandsmo GM (2015)
    Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes
    Clin Exp Metastasis, 32 (8), 755-67
    DOI 10.1007/s10585-015-9742-1, PubMed 26349943
  11. Eide N, Faye RS, Høifødt HK, Sandstad B, Qvale G, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2015)
    Immunomagnetic detection of micrometastatic cells in bone marrow of uveal melanoma patients: a paradox
    Acta Ophthalmol, 93 (1), 59-66
    DOI 10.1111/aos.12462, PubMed 25613126
  12. Eide N, Garred Ø, Beiske K, Fodstad Ø (2015)
    Bilateral uveal melanomas with different gene expression detected with 7 years interval
    Acta Ophthalmol, 94 (1), 99-102
    DOI 10.1111/aos.12857, PubMed 26496992
  13. Ekstrøm PO, Nakken S, Johansen M, Hovig E (2015)
    Automated amplicon design suitable for analysis of DNA variants by melting techniques
    BMC Res Notes, 8, 667
    DOI 10.1186/s13104-015-1624-8, PubMed 26559640
  14. Fernandez-Cuesta L, Sun R, Menon R, George J, Lorenz S, Meza-Zepeda LA, Peifer M, Plenker D, Heuckmann JM, Leenders F, Zander T, Dahmen I, Koker M, Schöttle J, Ullrich RT, Altmüller J, Becker C, Nürnberg P, Seidel H, Böhm D, Göke F, Ansén S, Russell PA, Wright GM, Wainer Z et al. (2015)
    Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data
    Genome Biol, 16 (1), 7
    DOI 10.1186/s13059-014-0558-0, PubMed 25650807
  15. Fretland ÅA, Kazaryan AM, Bjørnbeth BA, Flatmark K, Andersen MH, Tønnessen TI, Bjørnelv GM, Fagerland MW, Kristiansen R, Øyri K, Edwin B (2015)
    Open versus laparoscopic liver resection for colorectal liver metastases (the Oslo-CoMet Study): study protocol for a randomized controlled trial
    Trials, 16, 73
    DOI 10.1186/s13063-015-0577-5, PubMed 25872027
  16. Fromm B, Billipp T, Peck LE, Johansen M, Tarver JE, King BL, Newcomb JM, Sempere LF, Flatmark K, Hovig E, Peterson KJ (2015)
    A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome
    Annu Rev Genet, 49, 213-42
    DOI 10.1146/annurev-genet-120213-092023, PubMed 26473382
  17. Fromm B, Trelis M, Hackenberg M, Cantalapiedra F, Bernal D, Marcilla A (2015)
    The revised microRNA complement of Fasciola hepatica reveals a plethora of overlooked microRNAs and evidence for enrichment of immuno-regulatory microRNAs in extracellular vesicles
    Int J Parasitol, 45 (11), 697-702
    DOI 10.1016/j.ijpara.2015.06.002, PubMed 26183562
  18. Hektoen HH, Flatmark K, Andersson Y, Dueland S, Redalen KR, Ree AH (2015)
    Early increase in circulating carbonic anhydrase IX during neoadjuvant treatment predicts favourable outcome in locally advanced rectal cancer
    BMC Cancer, 15, 543
    DOI 10.1186/s12885-015-1557-6, PubMed 26205955
  19. Hektoen HH, Ree AH, Redalen KR, Flatmark K (2015)
    Sulfamate inhibitor S4 influences carbonic anhydrase IX ectodomain shedding in colorectal carcinoma cells
    J Enzyme Inhib Med Chem, 31 (5), 779-86
    DOI 10.3109/14756366.2015.1069286, PubMed 26244271
  20. Heramb C, Ekstrøm PO, Tharmaratnam K, Hovig E, Møller P, Mæhle L (2015)
    Ten modifiers of BRCA1 penetrance validated in a Norwegian series
    Hered Cancer Clin Pract, 13 (1), 14
    DOI 10.1186/s13053-015-0035-0, PubMed 26052370
  21. Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, King T, Bojmar L, Davies AE, Ararso Y, Zhang T, Zhang H, Hernandez J, Weiss JM, Dumont-Cole VD, Kramer K et al. (2015)
    Tumour exosome integrins determine organotropic metastasis
    Nature, 527 (7578), 329-35
    DOI 10.1038/nature15756, PubMed 26524530
  22. Ingthorsson S, Andersen K, Hilmarsdottir B, Maelandsmo GM, Magnusson MK, Gudjonsson T (2015)
    HER2 induced EMT and tumorigenicity in breast epithelial progenitor cells is inhibited by coexpression of EGFR
    Oncogene, 35 (32), 4244-55
    DOI 10.1038/onc.2015.489, PubMed 26686087
  23. Ishibashi M, Manning E, Shoubridge C, Krecsmarik M, Hawkins TA, Giacomotto J, Zhao T, Mueller T, Bader PI, Cheung SW, Stankiewicz P, Bain NL, Hackett A, Reddy CC, Mechaly AS, Peers B, Wilson SW, Lenhard B, Bally-Cuif L, Gecz J, Becker TS, Rinkwitz S (2015)
    Copy number variants in patients with intellectual disability affect the regulation of ARX transcription factor gene
    Hum Genet, 134 (11-12), 1163-82
    DOI 10.1007/s00439-015-1594-x, PubMed 26337422
  24. Jin Y, Wang L, Qu S, Sheng X, Kristian A, Mælandsmo GM, Pällmann N, Yuca E, Tekedereli I, Gorgulu K, Alpay N, Sood A, Lopez-Berestein G, Fazli L, Rennie P, Risberg B, Wæhre H, Danielsen HE, Ozpolat B, Saatcioglu F (2015)
    STAMP2 increases oxidative stress and is critical for prostate cancer
    EMBO Mol Med, 7 (3), 315-31
    DOI 10.15252/emmm.201404181, PubMed 25680860
  25. Ju YS, Tubio JM, Mifsud W, Fu B, Davies HR, Ramakrishna M, Li Y, Yates L, Gundem G, Tarpey PS, Behjati S, Papaemmanuil E, Martin S, Fullam A, Gerstung M, ICGC Prostate Cancer Working Group, ICGC Bone Cancer Working Group, ICGC Breast Cancer Working Group, Nangalia J, Green AR, Caldas C, Borg Å, Tutt A, Lee MT, van't Veer LJ et al. (2015)
    Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
    Genome Res, 25 (6), 814-24
    DOI 10.1101/gr.190470.115, PubMed 25963125
  26. Kanojia D, Nagata Y, Garg M, Lee DH, Sato A, Yoshida K, Sato Y, Sanada M, Mayakonda A, Bartenhagen C, Klein HU, Doan NB, Said JW, Mohith S, Gunasekar S, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Myklebost O, Yang H, Dugas M, Meza-Zepeda LA, Silberman AW, Forscher C et al. (2015)
    Genomic landscape of liposarcoma
    Oncotarget, 6 (40), 42429-44
    DOI 10.18632/oncotarget.6464, PubMed 26643872
  27. Lau C, Nygård S, Fure H, Olstad OK, Holden M, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
    CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray
    PLoS One, 10 (2), e0117261
    DOI 10.1371/journal.pone.0117261, PubMed 25706641
  28. Lau C, Olstad OK, Holden M, Nygård S, Fure H, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
    Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response
    Genom Data, 5, 176-83
    DOI 10.1016/j.gdata.2015.05.019, PubMed 26484252
  29. Magnussen GI, Emilsen E, Giller Fleten K, Engesæter B, Nähse-Kumpf V, Fjær R, Slipicevic A, Flørenes VA (2015)
    Combined inhibition of the cell cycle related proteins Wee1 and Chk1/2 induces synergistic anti-cancer effect in melanoma
    BMC Cancer, 15, 462
    DOI 10.1186/s12885-015-1474-8, PubMed 26054341
  30. Myklebost O (2015)
    Personalized cancer therapy for soft tissue sarcomas: progress and pitfalls
    Per Med, 12 (6), 593-602
    DOI 10.2217/pme.15.20, PubMed 29750616
  31. Møller P, Seppälä T, Bernstein I, Holinski-Feder E, Sala P, Evans DG, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Green K, Lalloo F, Sunde L, Mints M, Bertario L et al. (2015)
    Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database
    Gut, 66 (3), 464-472
    DOI 10.1136/gutjnl-2015-309675, PubMed 26657901
  32. Naderi EH, Skah S, Ugland H, Myklebost O, Sandnes DL, Torgersen ML, Josefsen D, Ruud E, Naderi S, Blomhoff HK (2015)
    Bone marrow stroma-derived PGE2 protects BCP-ALL cells from DNA damage-induced p53 accumulation and cell death
    Mol Cancer, 14 (1), 14
    DOI 10.1186/s12943-014-0278-9, PubMed 25623255
  33. Naville M, Ishibashi M, Ferg M, Bengani H, Rinkwitz S, Krecsmarik M, Hawkins TA, Wilson SW, Manning E, Chilamakuri CS, Wilson DI, Louis A, Lucy Raymond F, Rastegar S, Strähle U, Lenhard B, Bally-Cuif L, van Heyningen V, FitzPatrick DR, Becker TS, Roest Crollius H (2015)
    Long-range evolutionary constraints reveal cis-regulatory interactions on the human X chromosome
    Nat Commun, 6, 6904
    DOI 10.1038/ncomms7904, PubMed 25908307
  34. Nygaard V, Rødland EA, Hovig E (2015)
    Methods that remove batch effects while retaining group differences may lead to exaggerated confidence in downstream analyses
    Biostatistics, 17 (1), 29-39
    DOI 10.1093/biostatistics/kxv027, PubMed 26272994
  35. Pitman KE, Rusten E, Kristian A, Malinen E (2015)
    Variability of dynamic 18F-FDG-PET data in breast cancer xenografts
    Acta Oncol, 54 (9), 1399-407
    DOI 10.3109/0284186X.2015.1062140, PubMed 26217987
  36. Prasmickaite L, Berge G, Bettum IJ, Aamdal S, Hansson J, Bastholt L, Øijordsbakken M, Boye K, Mælandsmo GM (2015)
    Evaluation of serum osteopontin level and gene polymorphism as biomarkers: analyses from the Nordic Adjuvant Interferon alpha Melanoma trial
    Cancer Immunol Immunother, 64 (6), 769-76
    DOI 10.1007/s00262-015-1686-4, PubMed 25832001
  37. Redalen KR, Sitter B, Bathen TF, Grøholt KK, Hole KH, Dueland S, Flatmark K, Ree AH, Seierstad T (2015)
    High tumor glycine concentration is an adverse prognostic factor in locally advanced rectal cancer
    Radiother Oncol, 118 (2), 393-8
    DOI 10.1016/j.radonc.2015.11.031, PubMed 26705680
  38. Ree AH, Flatmark K, Saelen MG, Folkvord S, Dueland S, Geisler J, Redalen KR (2015)
    Tumor phosphatidylinositol 3-kinase signaling in therapy resistance and metastatic dissemination of rectal cancer: opportunities for signaling-adapted therapies
    Crit Rev Oncol Hematol, 95 (1), 114-24
    DOI 10.1016/j.critrevonc.2015.01.003, PubMed 25624177
  39. Repetto-Llamazares AH, Larsen RH, Patzke S, Fleten KG, Didierlaurent D, Pichard A, Pouget JP, Dahle J (2015)
    Targeted Cancer Therapy with a Novel Anti-CD37 Beta-Particle Emitting Radioimmunoconjugate for Treatment of Non-Hodgkin Lymphoma
    PLoS One, 10 (6), e0128816
    DOI 10.1371/journal.pone.0128816, PubMed 26066655
  40. Rizos E, Siafakas N, Katsantoni E, Skourti E, Salpeas V, Rizos I, Tsoporis JN, Kastania A, Filippopoulou A, Xiros N, Margaritis D, Parker TG, Papageorgiou C, Zoumpourlis V (2015)
    Correction: Let-7, Mir-98 and Mir-181 as Biomarkers for Cancer and Schizophrenia
    PLoS One, 10 (8), e0135863
    DOI 10.1371/journal.pone.0135863, PubMed 26266816
  41. Rustad EH, Dai HY, Hov H, Coward E, Beisvag V, Myklebost O, Hovig E, Nakken S, Vodák D, Meza-Zepeda LA, Sandvik AK, Wader KF, Misund K, Sundan A, Aarset H, Waage A (2015)
    BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis
    Blood Cancer J, 5 (3), e299
    DOI 10.1038/bcj.2015.24, PubMed 25794135
  42. Rydbeck H, Sandve GK, Ferkingstad E, Simovski B, Rye M, Hovig E (2015)
    ClusTrack: feature extraction and similarity measures for clustering of genome-wide data sets
    PLoS One, 10 (4), e0123261
    DOI 10.1371/journal.pone.0123261, PubMed 25879845
  43. Seierstad T, Hole KH, Grøholt KK, Dueland S, Ree AH, Flatmark K, Redalen KR (2015)
    MRI volumetry for prediction of tumour response to neoadjuvant chemotherapy followed by chemoradiotherapy in locally advanced rectal cancer
    Br J Radiol, 88 (1051), 20150097
    DOI 10.1259/bjr.20150097, PubMed 25899892
  44. Serguienko A, Grad I, Wennerstrøm AB, Meza-Zepeda LA, Thiede B, Stratford EW, Myklebost O, Munthe E (2015)
    Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA
    Oncotarget, 6 (4), 2451-65
    DOI 10.18632/oncotarget.3235, PubMed 25669981
  45. Skrbo N, Tenstad E, Mælandsmo GM, Sørlie T, Andersen K (2015)
    From autonomy to community; new perspectives on tumorigenicity and therapy resistance
    Cancer Treat Rev, 41 (10), 809-13
    DOI 10.1016/j.ctrv.2015.10.004, PubMed 26519005
  46. Srivastava SK, Bhardwaj A, Arora S, Tyagi N, Singh AP, Carter JE, Scammell JG, Fodstad Ø, Singh S (2015)
    Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasis
    Br J Cancer, 112 (11), 1772-81
    DOI 10.1038/bjc.2015.154, PubMed 25942396
  47. Tamhane T, Lllukkumbura R, Lu S, Maelandsmo GM, Haugen MH, Brix K (2015)
    Nuclear cathepsin L activity is required for cell cycle progression of colorectal carcinoma cells
    Biochimie, 122, 208-18
    DOI 10.1016/j.biochi.2015.09.003, PubMed 26343556
  48. Tamhane T, Wolters BK, Illukkumbura R, Maelandsmo GM, Haugen MH, Brix K (2015)
    Construction of a plasmid coding for green fluorescent protein tagged cathepsin L and data on expression in colorectal carcinoma cells
    Data Brief, 5, 468-75
    DOI 10.1016/j.dib.2015.09.022, PubMed 26594658
  49. Tran D, Verma K, Ward K, Diaz D, Kataria E, Torabi A, Almeida A, Malfoy B, Stratford EW, Mitchell DC, Bryan BA (2015)
    Functional genomics analysis reveals a MYC signature associated with a poor clinical prognosis in liposarcomas
    Am J Pathol, 185 (3), 717-28
    DOI 10.1016/j.ajpath.2014.11.024, PubMed 25622542
  50. Wendel T, Zhen Y, Suo Z, Bruheim S, Wiedlocha A (2015)
    The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo
    Exp Cell Res, 340 (2), 220-6
    DOI 10.1016/j.yexcr.2015.12.017, PubMed 26748184
  51. Wibom C, Späth F, Dahlin AM, Langseth H, Hovig E, Rajaraman P, Johannesen TB, Andersson U, Melin B (2015)
    Investigation of established genetic risk variants for glioma in prediagnostic samples from a population-based nested case-control study
    Cancer Epidemiol Biomarkers Prev, 24 (5), 810-6
    DOI 10.1158/1055-9965.EPI-14-1106, PubMed 25713050
  52. Zhao X, Rødland EA, Tibshirani R, Plevritis S (2015)
    Molecular subtyping for clinically defined breast cancer subgroups
    Breast Cancer Res, 17 (1), 29
    DOI 10.1186/s13058-015-0520-4, PubMed 25849221
  53. Østrup O, Pedersen HS, Holm HM, Hyttel P (2015)
    Analysis of nucleolar morphology and protein localization as an indicator of nuclear reprogramming
    Methods Mol Biol, 1222, 161-74
    DOI 10.1007/978-1-4939-1594-1_12, PubMed 25287345

Publications 2014

  1. Anninga JK, Cleton-Jansen AM, Hassan B, Amary MF, Baumhoer D, Blay JY, Brugieres L, Ferrari S, Jurgens H, Kempf-Bielack B, Kovar H, Myklebost O, Nathrath M, Picci P, Riegman P, Schilham MW, Soliman R, Stark DP, Strauss S, Sydes M, Tarpey P, Thomas D, Whelan J, Wilhelm M, Zamzam M et al. (2014)
    Workshop report on the 2nd Joint ENCCA/EuroSARC European bone sarcoma network meeting: integration of clinical trials with tumour biology
    Clin. Sarcoma Res., 4, 4
    DOI 10.1186/2045-3329-4-4
  2. Bagherifam S, Griffiths GW, Mælandsmo GM, Nyström B, Hasirci V, Hasirci N (2014)
    Poly(sebacic anhydride) nanocapsules as carriers: effects of preparation parameters on properties and release of doxorubicin
    J Microencapsul, 32 (2), 166-74
    DOI 10.3109/02652048.2014.973073, PubMed 25323326
  3. Bagherifam S, Skjeldal FM, Griffiths G, Mælandsmo GM, Engebråten O, Nyström B, Hasirci V, Hasirci N (2014)
    pH-responsive nano carriers for doxorubicin delivery
    Pharm Res, 32 (4), 1249-63
    DOI 10.1007/s11095-014-1530-0, PubMed 25288014
  4. Barøy T, Kresse SH, Skårn M, Stabell M, Castro R, Lauvrak S, Llombart-Bosch A, Myklebost O, Meza-Zepeda LA (2014)
    Reexpression of LSAMP inhibits tumor growth in a preclinical osteosarcoma model
    Mol Cancer, 13, 93
    DOI 10.1186/1476-4598-13-93, PubMed 24885297
  5. Brix K, McInnes J, Al-Hashimi A, Rehders M, Tamhane T, Haugen MH (2014)
    Proteolysis mediated by cysteine cathepsins and legumain-recent advances and cell biological challenges
    Protoplasma, 252 (3), 755-74
    DOI 10.1007/s00709-014-0730-0, PubMed 25398648
  6. Chilamakuri CS, Lorenz S, Madoui MA, Vodák D, Sun J, Hovig E, Myklebost O, Meza-Zepeda LA (2014)
    Performance comparison of four exome capture systems for deep sequencing
    BMC Genomics, 15 (1), 449
    DOI 10.1186/1471-2164-15-449, PubMed 24912484
  7. Clancy T, Hovig E (2014)
    From proteomes to complexomes in the era of systems biology
    Proteomics, 14 (1), 24-41
    DOI 10.1002/pmic.201300230, PubMed 24243660
  8. Clancy T, Hovig E (2014)
    Differential protein network analysis of the immune cell lineage
    Biomed Res Int, 2014, 363408
    DOI 10.1155/2014/363408, PubMed 25309909
  9. Esmaeili M, Moestue SA, Hamans BC, Veltien A, Kristian A, Engebråten O, Maelandsmo GM, Gribbestad IS, Bathen TF, Heerschap A (2014)
    In vivo ³¹P magnetic resonance spectroscopic imaging (MRSI) for metabolic profiling of human breast cancer xenografts
    J Magn Reson Imaging, 41 (3), 601-9
    DOI 10.1002/jmri.24588, PubMed 24532410
  10. Friis-Ottessen M, Burum-Auensen E, Schjølberg AR, Ekstrøm PO, Andersen SN, Clausen OP, De Angelis PM (2014)
    TP53/p53 alterations and Aurora A expression in progressor and non-progressor colectomies from patients with longstanding ulcerative colitis
    Int J Mol Med, 35 (1), 24-30
    DOI 10.3892/ijmm.2014.1974, PubMed 25333414
  11. Garsed DW, Marshall OJ, Corbin VD, Hsu A, Di Stefano L, Schröder J, Li J, Feng ZP, Kim BW, Kowarsky M, Lansdell B, Brookwell R, Myklebost O, Meza-Zepeda L, Holloway AJ, Pedeutour F, Choo KH, Damore MA, Deans AJ, Papenfuss AT, Thomas DM (2014)
    The architecture and evolution of cancer neochromosomes
    Cancer Cell, 26 (5), 653-67
    DOI 10.1016/j.ccell.2014.09.010, PubMed 25517748
  12. Grinde MT, Skrbo N, Moestue SA, Rødland EA, Borgan E, Kristian A, Sitter B, Bathen TF, Børresen-Dale AL, Mælandsmo GM, Engebraaten O, Sørlie T, Marangoni E, Gribbestad IS (2014)
    Interplay of choline metabolites and genes in patient-derived breast cancer xenografts
    Breast Cancer Res, 16 (1), R5
    DOI 10.1186/bcr3597, PubMed 24447408
  13. Haugen MH, Boye K, Nesland JM, Pettersen SJ, Egeland EV, Tamhane T, Brix K, Maelandsmo GM, Flatmark K (2014)
    High expression of the cysteine proteinase legumain in colorectal cancer - implications for therapeutic targeting
    Eur J Cancer, 51 (1), 9-17
    DOI 10.1016/j.ejca.2014.10.020, PubMed 25466510
  14. Hidalgo M, Amant F, Biankin AV, Budinská E, Byrne AT, Caldas C, Clarke RB, de Jong S, Jonkers J, Mælandsmo GM, Roman-Roman S, Seoane J, Trusolino L, Villanueva A (2014)
    Patient-derived xenograft models: an emerging platform for translational cancer research
    Cancer Discov, 4 (9), 998-1013
    DOI 10.1158/2159-8290.CD-14-0001, PubMed 25185190
  15. Håkelien AM, Bryne JC, Harstad KG, Lorenz S, Paulsen J, Sun J, Mikkelsen TS, Myklebost O, Meza-Zepeda LA (2014)
    The regulatory landscape of osteogenic differentiation
    Stem Cells, 32 (10), 2780-93
    DOI 10.1002/stem.1759, PubMed 24898411
  16. Ingebrigtsen VA, Boye K, Nesland JM, Nesbakken A, Flatmark K, Fodstad Ø (2014)
    B7-H3 expression in colorectal cancer: associations with clinicopathological parameters and patient outcome
    BMC Cancer, 14, 602
    DOI 10.1186/1471-2407-14-602, PubMed 25139714
  17. Kristian A, Riss P, Qu H, Milde M, Schoultz BW, Engebraaten O, Mælandsmo GM, Malinen E (2014)
    Positron emission tomography and pharmacokinetics of 2-[18F]-fluoroethyl choline for metabolic studies in breast cancer xenografts
    Acta Oncol, 53 (8), 1086-92
    DOI 10.3109/0284186X.2014.934398, PubMed 25017377
  18. Metsu S, Rooms L, Rainger J, Taylor MS, Bengani H, Wilson DI, Chilamakuri CS, Morrison H, Vandeweyer G, Reyniers E, Douglas E, Thompson G, Haan E, Gecz J, Fitzpatrick DR, Kooy RF (2014)
    FRA2A is a CGG repeat expansion associated with silencing of AFF3
    PLoS Genet, 10 (4), e1004242
    DOI 10.1371/journal.pgen.1004242, PubMed 24763282
  19. Momtazi L, Bagherifam S, Singh G, Hofgaard A, Hakkarainen M, Glomm WR, Roos N, Mælandsmo GM, Griffiths G, Nyström B (2014)
    Synthesis, characterization, and cellular uptake of magnetic nanocarriers for cancer drug delivery
    J Colloid Interface Sci, 433, 76-85
    DOI 10.1016/j.jcis.2014.07.013, PubMed 25112915
  20. Nilsen LB, Fangberget A, Geier OM, Engebraaten O, Borgen E, Olsen DR, Seierstad T (2014)
    Associations between tumor vascularization assessed by in vivo DCE-MRI and the presence of disseminated tumor cells in bone marrow in breast cancer patients at the time of diagnosis
    J Magn Reson Imaging, 40 (6), 1382-91
    DOI 10.1002/jmri.24502, PubMed 24470360
  21. Norum JH, Andersen K, Sørlie T (2014)
    Lessons learned from the intrinsic subtypes of breast cancer in the quest for precision therapy
    Br J Surg, 101 (8), 925-38
    DOI 10.1002/bjs.9562, PubMed 24849143
  22. Nygren MK, Tekle C, Ingebrigtsen VA, Mäkelä R, Krohn M, Aure MR, Nunes-Xavier CE, Perälä M, Tramm T, Alsner J, Overgaard J, Nesland JM, Borgen E, Børresen-Dale AL, Fodstad Ø, Sahlberg KK, Leivonen SK (2014)
    Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c
    Br J Cancer, 110 (8), 2072-80
    DOI 10.1038/bjc.2014.113, PubMed 24577056
  23. Nygård S, Reitan T, Clancy T, Nygaard V, Bjørnstad J, Skrbic B, Tønnessen T, Christensen G, Hovig E (2014)
    Identifying pathogenic processes by integrating microarray data with prior knowledge
    BMC Bioinformatics, 15, 115
    DOI 10.1186/1471-2105-15-115, PubMed 24758699
  24. Nygaard V, Prasmickaite L, Vasiliauskaite K, Clancy T, Hovig E (2014)
    Melanoma brain colonization involves the emergence of a brain-adaptive phenotype
    Oncoscience, 1 (1), 82-94
    DOI 10.18632/oncoscience.11, PubMed 25593989
  25. Ostrup O, Reiner AH, Aleström P, Collas P (2014)
    The specific alteration of histone methylation profiles by DZNep during early zebrafish development
    Biochim Biophys Acta, 1839 (11), 1307-15
    DOI 10.1016/j.bbagrm.2014.09.013, PubMed 25260724
  26. Panagopoulos I, Bjerkehagen B, Gorunova L, Berner JM, Boye K, Heim S (2014)
    Several fusion genes identified by whole transcriptome sequencing in a spindle cell sarcoma with rearrangements of chromosome arm 12q and MDM2 amplification
    Int J Oncol, 45 (5), 1829-36
    DOI 10.3892/ijo.2014.2605, PubMed 25176350
  27. Panagopoulos I, Gorunova L, Bjerkehagen B, Boye K, Heim S (2014)
    Chromosome aberrations and HEY1-NCOA2 fusion gene in a mesenchymal chondrosarcoma
    Oncol Rep, 32 (1), 40-4
    DOI 10.3892/or.2014.3180, PubMed 24839999
  28. Paulsen J, Rødland EA, Holden L, Holden M, Hovig E (2014)
    A statistical model of ChIA-PET data for accurate detection of chromatin 3D interactions
    Nucleic Acids Res, 42 (18), e143
    DOI 10.1093/nar/gku738, PubMed 25114054
  29. Paulsen J, Sandve GK, Gundersen S, Lien TG, Trengereid K, Hovig E (2014)
    HiBrowse: multi-purpose statistical analysis of genome-wide chromatin 3D organization
    Bioinformatics, 30 (11), 1620-2
    DOI 10.1093/bioinformatics/btu082, PubMed 24511080
  30. Pettersen EO, Ebbesen P, Gieling RG, Williams KJ, Dubois L, Lambin P, Ward C, Meehan J, Kunkler IH, Langdon SP, Ree AH, Flatmark K, Lyng H, Calzada MJ, Peso LD, Landazuri MO, Görlach A, Flamm H, Kieninger J, Urban G, Weltin A, Singleton DC, Haider S, Buffa FM, Harris AL et al. (2014)
    Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium
    J Enzyme Inhib Med Chem, 30 (5), 689-721
    DOI 10.3109/14756366.2014.966704, PubMed 25347767
  31. Ree AH, Meltzer S, Flatmark K, Dueland S, Kalanxhi E (2014)
    Biomarkers of treatment toxicity in combined-modality cancer therapies with radiation and systemic drugs: study design, multiplex methods, molecular networks
    Int J Mol Sci, 15 (12), 22835-56
    DOI 10.3390/ijms151222835, PubMed 25501337
  32. Ree AH, Saelen MG, Kalanxhi E, Østensen IH, Schee K, Røe K, Abrahamsen TW, Dueland S, Flatmark K (2014)
    Biomarkers of histone deacetylase inhibitor activity in a phase 1 combined-modality study with radiotherapy
    PLoS One, 9 (2), e89750
    DOI 10.1371/journal.pone.0089750, PubMed 24587009
  33. Skrbo N, Hjortland GO, Kristian A, Holm R, Nord S, Prasmickaite L, Engebraaten O, Mælandsmo GM, Sørlie T, Andersen K (2014)
    Differential in vivo tumorigenicity of distinct subpopulations from a luminal-like breast cancer xenograft
    PLoS One, 9 (11), e113278
    DOI 10.1371/journal.pone.0113278, PubMed 25419568
  34. Skårn M, Noordhuis P, Wang MY, Veuger M, Kresse SH, Egeland EV, Micci F, Namløs HM, Håkelien AM, Olafsrud SM, Lorenz S, Haraldsen G, Kvalheim G, Meza-Zepeda LA, Myklebost O (2014)
    Generation and characterization of an immortalized human mesenchymal stromal cell line
    Stem Cells Dev, 23 (19), 2377-89
    DOI 10.1089/scd.2013.0599, PubMed 24857590
  35. Tubio JMC, Li Y, Ju YS, Martincorena I, Cooke SL, Tojo M, Gundem G, Pipinikas CP, Zamora J, Raine K, Menzies A, Roman-Garcia P, Fullam A, Gerstung M, Shlien A, Tarpey PS, Papaemmanuil E, Knappskog S, Van Loo P, Ramakrishna M, Davies HR, Marshall J, Wedge DC, Teague JW, Butler AP et al. (2014)
    Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
    Science, 345 (6196), 1251343
    DOI 10.1126/science.1251343, PubMed 25082706
  36. Wennerström AB, Lothe IM, Sandhu V, Kure EH, Myklebost O, Munthe E (2014)
    Generation and characterisation of novel pancreatic adenocarcinoma xenograft models and corresponding primary cell lines
    PLoS One, 9 (8), e103873
    DOI 10.1371/journal.pone.0103873, PubMed 25148029
  37. Wiiger MT, Bideli H, Fodstad O, Flatmark K, Andersson Y (2014)
    The MOC31PE immunotoxin reduces cell migration and induces gene expression and cell death in ovarian cancer cells
    J Ovarian Res, 7, 23
    DOI 10.1186/1757-2215-7-23, PubMed 24528603

Publications 2013

  1. Behjati S, Tarpey PS, Presneau N, Scheipl S, Pillay N, Van Loo P, Wedge DC, Cooke SL, Gundem G, Davies H, Nik-Zainal S, Martin S, McLaren S, Goodie V, Robinson B, Butler A, Teague JW, Halai D, Khatri B, Myklebost O, Baumhoer D, Jundt G, Hamoudi R, Tirabosco R, Amary MF et al. (2013)
    Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone
    Nat Genet, 45 (12), 1479-82
    DOI 10.1038/ng.2814, PubMed 24162739
  2. Bettum IJ, Vasiliauskaite K, Nygaard V, Clancy T, Pettersen SJ, Tenstad E, Mælandsmo GM, Prasmickaite L (2013)
    Metastasis-associated protein S100A4 induces a network of inflammatory cytokines that activate stromal cells to acquire pro-tumorigenic properties
    Cancer Lett, 344 (1), 28-39
    DOI 10.1016/j.canlet.2013.10.036, PubMed 24215866
  3. Bianchini L, Birtwisle L, Saâda E, Bazin A, Long E, Roussel JF, Michiels JF, Forest F, Dani C, Myklebost O, Birtwisle-Peyrottes I, Pedeutour F (2013)
    Identification of PPAP2B as a novel recurrent translocation partner gene of HMGA2 in lipomas
    Genes Chromosomes Cancer, 52 (6), 580-90
    DOI 10.1002/gcc.22055, PubMed 23508853
  4. Bruheim S, Sandvold ML, Mælandsmo GM, Fodstad O (2013)
    Antitumor activity of elacytarabine combined with bevacizumab, cetuximab and trastuzumab in human NSCLC xenografts
    Anticancer Res, 33 (9), 3615-21
    PubMed 24023287
  5. Bøe SL, Hovig E (2013)
    Enhancing nucleic acid delivery by photochemical internalization
    Ther Deliv, 4 (9), 1125-40
    DOI 10.4155/tde.13.78, PubMed 24024512
  6. Bøe SL, Hovig E (2013)
    Light-induced mRNA transfection
    Methods Mol Biol, 969, 89-100
    DOI 10.1007/978-1-62703-260-5_6, PubMed 23296929
  7. Bøe SL, Jørgensen JA, Longva AS, Lavelle T, Sæbøe-Larssen S, Hovig E (2013)
    Light-controlled modulation of gene expression using polyamidoamine formulations
    Nucleic Acid Ther, 23 (2), 160-5
    DOI 10.1089/nat.2012.0413, PubMed 23530684
  8. Clancy T, Rødland EA, Nygard S, Hovig E (2013)
    Predicting physical interactions between protein complexes
    Mol Cell Proteomics, 12 (6), 1723-34
    DOI 10.1074/mcp.O112.019828, PubMed 23438732
  9. Desai S, Liu Z, Yao J, Patel N, Chen J, Wu Y, Ahn EE, Fodstad O, Tan M (2013)
    Heat shock factor 1 (HSF1) controls chemoresistance and autophagy through transcriptional regulation of autophagy-related protein 7 (ATG7)
    J Biol Chem, 288 (13), 9165-76
    DOI 10.1074/jbc.M112.422071, PubMed 23386620
  10. Doorn J, Fernandes HA, Le BQ, van de Peppel J, van Leeuwen JP, De Vries MR, Aref Z, Quax PH, Myklebost O, Saris DB, van Blitterswijk CA, de Boer J (2013)
    A small molecule approach to engineering vascularized tissue
    Biomaterials, 34 (12), 3053-63
    DOI 10.1016/j.biomaterials.2012.12.037, PubMed 23369216
  11. Eide T, Ramberg H, Glackin C, Tindall D, Taskén KA (2013)
    TWIST1, A novel androgen-regulated gene, is a target for NKX3-1 in prostate cancer cells
    Cancer Cell Int, 13 (1), 4
    DOI 10.1186/1475-2867-13-4, PubMed 23368843
  12. Engebraaten O, Vollan HKM, Børresen-Dale AL (2013)
    Triple-negative breast cancer and the need for new therapeutic targets
    Am J Pathol, 183 (4), 1064-1074
    DOI 10.1016/j.ajpath.2013.05.033, PubMed 23920327
  13. Esmaeili M, Bathen TF, Engebråten O, Mælandsmo GM, Gribbestad IS, Moestue SA (2013)
    Quantitative (31)P HR-MAS MR spectroscopy for detection of response to PI3K/mTOR inhibition in breast cancer xenografts
    Magn Reson Med, 71 (6), 1973-81
    DOI 10.1002/mrm.24869, PubMed 23878023
  14. Flatmark K, Guldvik IJ, Svensson H, Fleten KG, Flørenes VA, Reed W, Giercksky KE, Fodstad Ø, Andersson Y (2013)
    Immunotoxin targeting EpCAM effectively inhibits peritoneal tumor growth in experimental models of mucinous peritoneal surface malignancies
    Int J Cancer, 133 (6), 1497-506
    DOI 10.1002/ijc.28158, PubMed 23494569
  15. Friedman R, Boye K, Flatmark K (2013)
    Molecular modelling and simulations in cancer research
    Biochim Biophys Acta, 1836 (1), 1-14
    DOI 10.1016/j.bbcan.2013.02.001, PubMed 23416097
  16. Fromm B, Worren MM, Hahn C, Hovig E, Bachmann L (2013)
    Substantial loss of conserved and gain of novel MicroRNA families in flatworms
    Mol Biol Evol, 30 (12), 2619-28
    DOI 10.1093/molbev/mst155, PubMed 24025793
  17. Grytli HH, Fagerland MW, Fosså SD, Taskén KA (2013)
    Association between use of β-blockers and prostate cancer-specific survival: a cohort study of 3561 prostate cancer patients with high-risk or metastatic disease
    Eur Urol, 65 (3), 635-41
    DOI 10.1016/j.eururo.2013.01.007, PubMed 23351721
  18. Grytli HH, Fagerland MW, Fosså SD, Taskén KA (2013)
    Reply to Chris R. Cardwell, Samy Suissa and Liam J. Murray's letter to the editor re: Helene Hartvedt Grytli, Morten Wang Fagerland, Sophie D. Fosså, Kristin Austlid Taskén. Association between use of β-blockers and prostate cancer-specific survival: a cohort study of 3561 prostate cancer patients with high-risk or metastatic disease. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2013.01.007
    Eur Urol, 64 (1), e11-2
    DOI 10.1016/j.eururo.2013.03.045, PubMed 23602404
  19. Haugen MH, Johansen HT, Pettersen SJ, Solberg R, Brix K, Flatmark K, Maelandsmo GM (2013)
    Nuclear legumain activity in colorectal cancer
    PLoS One, 8 (1), e52980
    DOI 10.1371/journal.pone.0052980, PubMed 23326369
  20. Haugsten EM, Oppelt A, Wesche J (2013)
    Phosphatidylinositol 5-phosphate is a second messenger important for cell migration
    Commun Integr Biol, 6 (5), e25446
    DOI 10.4161/cib.25446, PubMed 24265857
  21. Herlofsen SR, Bryne JC, Høiby T, Wang L, Issner R, Zhang X, Coyne MJ, Boyle P, Gu H, Meza-Zepeda LA, Collas P, Mikkelsen TS, Brinchmann JE (2013)
    Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells
    BMC Genomics, 14, 105
    DOI 10.1186/1471-2164-14-105, PubMed 23414147
  22. Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
    High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
    PLoS One, 8 (10), e77232
    DOI 10.1371/journal.pone.0077232, PubMed 24194875
  23. Itkonen HM, Minner S, Guldvik IJ, Sandmann MJ, Tsourlakis MC, Berge V, Svindland A, Schlomm T, Mills IG (2013)
    O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer cells
    Cancer Res, 73 (16), 5277-87
    DOI 10.1158/0008-5472.CAN-13-0549, PubMed 23720054
  24. Jin Y, Qu S, Tesikova M, Wang L, Kristian A, Mælandsmo GM, Kong H, Zhang T, Jerónimo C, Teixeira MR, Yuca E, Tekedereli I, Gorgulu K, Alpay N, Sood AK, Lopez-Berestein G, Danielsen HE, Ozpolat B, Saatcioglu F (2013)
    Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer
    Proc Natl Acad Sci U S A, 110 (28), E2572-81
    DOI 10.1073/pnas.1304318110, PubMed 23798432
  25. Jørgensen JA, Longva AS, Hovig E, Bøe SL (2013)
    Evaluation of biodegradable peptide carriers for light-directed targeting
    Nucleic Acid Ther, 23 (2), 131-9
    DOI 10.1089/nat.2012.0403, PubMed 23405950
  26. Kongsgaard A, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
    Clinical significance of disseminated tumour cells in non-small cell lung cancer
    Br J Cancer, 109 (5), 1264-70
    DOI 10.1038/bjc.2013.450, PubMed 23942067
  27. Kongsgaard A, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
    Osteopontin is a prognostic biomarker in non-small cell lung cancer
    BMC Cancer, 13, 540
    DOI 10.1186/1471-2407-13-540, PubMed 24215488
  28. Kristian A, Nilsen LB, Røe K, Revheim ME, Engebråten O, Mælandsmo GM, Holm R, Malinen E, Seierstad T (2013)
    Dynamic (18) F-FDG PET for Assessment of Tumor Physiology in Two Breast Carcinoma Xenografts
    Nucl Med Mol Imaging, 47 (3), 173-80
    DOI 10.1007/s13139-013-0211-y, PubMed 24900104
  29. Kristian A, Revheim ME, Qu H, Mælandsmo GM, Engebråten O, Seierstad T, Malinen E (2013)
    Dynamic (18)F-FDG-PET for monitoring treatment effect following anti-angiogenic therapy in triple-negative breast cancer xenografts
    Acta Oncol, 52 (7), 1566-72
    DOI 10.3109/0284186X.2013.813634, PubMed 23984812
  30. Kuijjer ML, Peterse EF, van den Akker BE, Briaire-de Bruijn IH, Serra M, Meza-Zepeda LA, Myklebost O, Hassan AB, Hogendoorn PC, Cleton-Jansen AM (2013)
    IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma
    BMC Cancer, 13, 245
    DOI 10.1186/1471-2407-13-245, PubMed 23688189
  31. Lando M, Wilting SM, Snipstad K, Clancy T, Bierkens M, Aarnes EK, Holden M, Stokke T, Sundfør K, Holm R, Kristensen GB, Steenbergen RD, Lyng H (2013)
    Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling
    J Pathol, 230 (1), 59-69
    DOI 10.1002/path.4168, PubMed 23335387
  32. Lauvrak SU, Munthe E, Kresse SH, Stratford EW, Namløs HM, Meza-Zepeda LA, Myklebost O (2013)
    Functional characterisation of osteosarcoma cell lines and identification of mRNAs and miRNAs associated with aggressive cancer phenotypes
    Br J Cancer, 109 (8), 2228-36
    DOI 10.1038/bjc.2013.549, PubMed 24064976
  33. Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Mælandsmo GM, Engebraaten O (2013)
    Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
    Clin Cancer Res, 20 (2), 404-12
    DOI 10.1158/1078-0432.CCR-13-1865, PubMed 24192926
  34. Lorvik KB, Haabeth OA, Clancy T, Bogen B, Corthay A (2013)
    Molecular profiling of tumor-specific TH1 cells activated in vivo
    Oncoimmunology, 2 (5), e24383
    DOI 10.4161/onci.24383, PubMed 23762808
  35. Moestue SA, Dam CG, Gorad SS, Kristian A, Bofin A, Mælandsmo GM, Engebråten O, Gribbestad IS, Bjørkøy G (2013)
    Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer
    Breast Cancer Res, 15 (1), R16
    DOI 10.1186/bcr3391, PubMed 23448424
  36. Moestue SA, Huuse EM, Lindholm EM, Bofin A, Engebraaten O, Mælandsmo GM, Akslen LA, Gribbestad IS (2013)
    Low-molecular contrast agent dynamic contrast-enhanced (DCE)-MRI and diffusion-weighted (DW)-MRI in early assessment of bevacizumab treatment in breast cancer xenografts
    J Magn Reson Imaging, 38 (5), 1043-53
    DOI 10.1002/jmri.24079, PubMed 23908122
  37. Nome T, Thomassen GO, Bruun J, Ahlquist T, Bakken AC, Hoff AM, Rognum T, Nesbakken A, Lorenz S, Sun J, Barros-Silva JD, Lind GE, Myklebost O, Teixeira MR, Meza-Zepeda LA, Lothe RA, Skotheim RI (2013)
    Common fusion transcripts identified in colorectal cancer cell lines by high-throughput RNA sequencing
    Transl Oncol, 6 (5), 546-53
    DOI 10.1593/tlo.13457, PubMed 24151535
  38. Paulsen J, Lien TG, Sandve GK, Holden L, Borgan O, Glad IK, Hovig E (2013)
    Handling realistic assumptions in hypothesis testing of 3D co-localization of genomic elements
    Nucleic Acids Res, 41 (10), 5164-74
    DOI 10.1093/nar/gkt227, PubMed 23571755
  39. Qu S, Olafsrud SM, Meza-Zepeda LA, Saatcioglu F (2013)
    Rapid gene expression changes in peripheral blood lymphocytes upon practice of a comprehensive yoga program
    PLoS One, 8 (4), e61910
    DOI 10.1371/journal.pone.0061910, PubMed 23613970
  40. Ragnum HB, Røe K, Holm R, Vlatkovic L, Nesland JM, Aarnes EK, Ree AH, Flatmark K, Seierstad T, Lilleby W, Lyng H (2013)
    Hypoxia-independent downregulation of hypoxia-inducible factor 1 targets by androgen deprivation therapy in prostate cancer
    Int J Radiat Oncol Biol Phys, 87 (4), 753-60
    DOI 10.1016/j.ijrobp.2013.07.023, PubMed 24035332
  41. Revheim ME, Kristian A, Malinen E, Bruland ØS, Berner JM, Holm R, Joensuu H, Seierstad T (2013)
    Intermittent and continuous imatinib in a human GIST xenograft model carrying KIT exon 17 resistance mutation D816H
    Acta Oncol, 52 (4), 776-82
    DOI 10.3109/0284186X.2013.770920, PubMed 23480638
  42. Rødland EA (2013)
    Compact representation of k-mer de Bruijn graphs for genome read assembly
    BMC Bioinformatics, 14, 313
    DOI 10.1186/1471-2105-14-313, PubMed 24152242
  43. Røe K, Bratland Å, Vlatkovic L, Ragnum HB, Saelen MG, Olsen DR, Marignol L, Ree AH (2013)
    Hypoxic tumor kinase signaling mediated by STAT5A in development of castration-resistant prostate cancer
    PLoS One, 8 (5), e63723
    DOI 10.1371/journal.pone.0063723, PubMed 23675504
  44. Sandberg CJ, Altschuler G, Jeong J, Strømme KK, Stangeland B, Murrell W, Grasmo-Wendler UH, Myklebost O, Helseth E, Vik-Mo EO, Hide W, Langmoen IA (2013)
    Comparison of glioma stem cells to neural stem cells from the adult human brain identifies dysregulated Wnt- signaling and a fingerprint associated with clinical outcome
    Exp Cell Res, 319 (14), 2230-43
    DOI 10.1016/j.yexcr.2013.06.004, PubMed 23791939
  45. Sandve GK, Gundersen S, Johansen M, Glad IK, Gunathasan K, Holden L, Holden M, Liestøl K, Nygård S, Nygaard V, Paulsen J, Rydbeck H, Trengereid K, Clancy T, Drabløs F, Ferkingstad E, Kalas M, Lien T, Rye MB, Frigessi A, Hovig E (2013)
    The Genomic HyperBrowser: an analysis web server for genome-scale data
    Nucleic Acids Res, 41 (Web Server issue), W133-41
    DOI 10.1093/nar/gkt342, PubMed 23632163
  46. Sandve GK, Nekrutenko A, Taylor J, Hovig E (2013)
    Ten simple rules for reproducible computational research
    PLoS Comput Biol, 9 (10), e1003285
    DOI 10.1371/journal.pcbi.1003285, PubMed 24204232
  47. Schee K, Lorenz S, Worren MM, Günther CC, Holden M, Hovig E, Fodstad O, Meza-Zepeda LA, Flatmark K (2013)
    Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer
    PLoS One, 8 (6), e66165
    DOI 10.1371/journal.pone.0066165, PubMed 23824282
  48. Skårn M, Barøy T, Stratford EW, Myklebost O (2013)
    Epigenetic regulation and functional characterization of microRNA-142 in mesenchymal cells
    PLoS One, 8 (11), e79231
    DOI 10.1371/journal.pone.0079231, PubMed 24236112
  49. Stratford EW, Bostad M, Castro R, Skarpen E, Berg K, Høgset A, Myklebost O, Selbo PK (2013)
    Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity
    Biochim Biophys Acta, 1830 (8), 4235-43
    DOI 10.1016/j.bbagen.2013.04.033, PubMed 23643966
  50. Stratford EW, Daffinrud J, Munthe E, Castro R, Waaler J, Krauss S, Myklebost O (2013)
    The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines
    Cancer Med, 3 (1), 36-46
    DOI 10.1002/cam4.170, PubMed 24403055
  51. Sørensen O, Andersen AM, Kristian A, Giercksky KE, Flatmark K (2013)
    Impact of hyperthermia on pharmacokinetics of intraperitoneal mitomycin C in rats investigated by microdialysis
    J Surg Oncol, 109 (6), 521-6
    DOI 10.1002/jso.23527, PubMed 24347444
  52. Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
    Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
    Carcinogenesis, 35 (1), 76-85
    DOI 10.1093/carcin/bgt333, PubMed 24104550
  53. Wang P, Gao Q, Suo Z, Munthe E, Solberg S, Ma L, Wang M, Westerdaal NA, Kvalheim G, Gaudernack G (2013)
    Identification and characterization of cells with cancer stem cell properties in human primary lung cancer cell lines
    PLoS One, 8 (3), e57020 (Retracted)
    DOI 10.1371/journal.pone.0057020, PubMed 23469181
  54. Wang P, Suo Z, Wang M, Høifødt HK, Fodstad O, Gaudernack G, Kvalheim G (2013)
    In vitro and in vivo properties of CD133 expressing cells from human lung cancer cell lines
    Exp Hematol Oncol, 2 (1), 16
    DOI 10.1186/2162-3619-2-16, PubMed 23738757
  55. Yri OE, Ekstrøm PO, Hilden V, Gaudernack G, Liestøl K, Smeland EB, Holte H (2013)
    Influence of polymorphisms in genes encoding immunoregulatory proteins and metabolizing enzymes on susceptibility and outcome in patients with diffuse large B-cell lymphoma treated with rituximab
    Leuk Lymphoma, 54 (10), 2205-14
    DOI 10.3109/10428194.2013.774392, PubMed 23391141
  56. Zhai H, Fesler A, Schee K, Fodstad O, Flatmark K, Ju J (2013)
    Clinical significance of long intergenic noncoding RNA-p21 in colorectal cancer
    Clin Colorectal Cancer, 12 (4), 261-6
    DOI 10.1016/j.clcc.2013.06.003, PubMed 24012455

Publications 2012

  1. Bjørnstad LG, Meza TJ, Otterlei M, Olafsrud SM, Meza-Zepeda LA, Falnes PØ (2012)
    Human ALKBH4 interacts with proteins associated with transcription
    PLoS One, 7 (11), e49045
    DOI 10.1371/journal.pone.0049045, PubMed 23145062
  2. Borgan E, Lindholm EM, Moestue S, Mælandsmo GM, Lingjærde OC, Gribbestad IS, Børresen-Dale AL, Engebraaten O, Sørlie T (2012)
    Subtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts
    Mol Oncol, 7 (1), 130-42
    DOI 10.1016/j.molonc.2012.10.005, PubMed 23142657
  3. Boye K, Nesland JM, Sandstad B, Haugland Haugen M, Mælandsmo GM, Flatmark K (2012)
    EMMPRIN is associated with S100A4 and predicts patient outcome in colorectal cancer
    Br J Cancer, 107 (4), 667-74
    DOI 10.1038/bjc.2012.293, PubMed 22782346
  4. Brusegard K, Stavnes HT, Nymoen DA, Flatmark K, Trope CG, Davidson B (2012)
    Rab25 is overexpressed in Müllerian serous carcinoma compared to malignant mesothelioma
    Virchows Arch, 460 (2), 193-202
    DOI 10.1007/s00428-011-1191-x, PubMed 22249560
  5. Cejudo-Marín R, Tárrega C, Nunes-Xavier CE, Pulido R (2012)
    Caspase-3 cleavage of DUSP6/MKP3 at the interdomain region generates active MKP3 fragments that regulate ERK1/2 subcellular localization and function
    J Mol Biol, 420 (1-2), 128-38
    DOI 10.1016/j.jmb.2012.04.004, PubMed 22504224
  6. Chymkowitch P, Eldholm V, Lorenz S, Zimmermann C, Lindvall JM, Bjørås M, Meza-Zepeda LA, Enserink JM (2012)
    Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes
    Proc Natl Acad Sci U S A, 109 (26), 10450-5
    DOI 10.1073/pnas.1200067109, PubMed 22689984
  7. Ding Y, Liu Z, Desai S, Zhao Y, Liu H, Pannell LK, Yi H, Wright ER, Owen LB, Dean-Colomb W, Fodstad O, Lu J, LeDoux SP, Wilson GL, Tan M (2012)
    Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism
    Nat Commun, 3, 1271
    DOI 10.1038/ncomms2236, PubMed 23232401
  8. Eide N, Hoifødt HK, Nesland JM, Faye RS, Qvale GA, Faber RT, Jebsen P, Kvalheim G, Fodstad Ø (2012)
    Disseminated tumour cells in bone marrow of patients with uveal melanoma
    Acta Ophthalmol, 91 (4), 343-8
    DOI 10.1111/j.1755-3768.2012.02449.x, PubMed 22632270
  9. Ekstrøm PO, Warren DJ, Thilly WG (2012)
    Separation principles of cycling temperature capillary electrophoresis
    Electrophoresis, 33 (7), 1162-8
    DOI 10.1002/elps.201100550, PubMed 22539319
  10. Engesæter B, Engebraaten O, Flørenes VA, Mælandsmo GM (2012)
    Dacarbazine and the agonistic TRAIL receptor-2 antibody lexatumumab induce synergistic anticancer effects in melanoma
    PLoS One, 7 (9), e45492
    DOI 10.1371/journal.pone.0045492, PubMed 23029050
  11. Grytli HH, Fagerland MW, Fosså SD, Taskén KA, Håheim LL (2012)
    Use of β-blockers is associated with prostate cancer-specific survival in prostate cancer patients on androgen deprivation therapy
    Prostate, 73 (3), 250-60
    DOI 10.1002/pros.22564, PubMed 22821802
  12. Ingebrigtsen VA, Boye K, Tekle C, Nesland JM, Flatmark K, Fodstad O (2012)
    B7-H3 expression in colorectal cancer: nuclear localization strongly predicts poor outcome in colon cancer
    Int J Cancer, 131 (11), 2528-36
    DOI 10.1002/ijc.27566, PubMed 22473715
  13. Jørgensen JA, Hovig E, Bøe SL (2012)
    Potent gene silencing in vitro at physiological pH using chitosan polymers
    Nucleic Acid Ther, 22 (2), 96-102
    DOI 10.1089/nat.2011.0335, PubMed 22480314
  14. Kernstock S, Davydova E, Jakobsson M, Moen A, Pettersen S, Mælandsmo GM, Egge-Jacobsen W, Falnes PØ (2012)
    Lysine methylation of VCP by a member of a novel human protein methyltransferase family
    Nat Commun, 3, 1038
    DOI 10.1038/ncomms2041, PubMed 22948820
  15. Kongsgaard A, Lund-Iversen M, Berge G, Brustugun OT, Solberg SK, Mælandsmo GM, Boye K (2012)
    Expression of S100A4, ephrin-A1 and osteopontin in non-small cell lung cancer
    BMC Cancer, 12, 333
    DOI 10.1186/1471-2407-12-333, PubMed 22853000
  16. Kresse SH, Rydbeck H, Skårn M, Namløs HM, Barragan-Polania AH, Cleton-Jansen AM, Serra M, Liestøl K, Hogendoorn PC, Hovig E, Myklebost O, Meza-Zepeda LA (2012)
    Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma
    PLoS One, 7 (11), e48262
    DOI 10.1371/journal.pone.0048262, PubMed 23144859
  17. Kuijjer ML, Rydbeck H, Kresse SH, Buddingh EP, Lid AB, Roelofs H, Bürger H, Myklebost O, Hogendoorn PC, Meza-Zepeda LA, Cleton-Jansen AM (2012)
    Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data
    Genes Chromosomes Cancer, 51 (7), 696-706
    DOI 10.1002/gcc.21956, PubMed 22454324
  18. Lindholm EM, Kristian A, Nalwoga H, Krüger K, Nygård S, Akslen LA, Mælandsmo GM, Engebraaten O (2012)
    Effect of antiangiogenic therapy on tumor growth, vasculature and kinase activity in basal- and luminal-like breast cancer xenografts
    Mol Oncol, 6 (4), 418-27
    DOI 10.1016/j.molonc.2012.03.006, PubMed 22521242
  19. Liu F, Kuo WP, Jenssen TK, Hovig E (2012)
    Performance comparison of multiple microarray platforms for gene expression profiling
    Methods Mol Biol, 802, 141-55
    DOI 10.1007/978-1-61779-400-1_10, PubMed 22130879
  20. Liu Z, Liu H, Desai S, Schmitt DC, Zhou M, Khong HT, Klos KS, McClellan S, Fodstad O, Tan M (2012)
    miR-125b functions as a key mediator for snail-induced stem cell propagation and chemoresistance
    J Biol Chem, 288 (6), 4334-45
    DOI 10.1074/jbc.M112.419168, PubMed 23255607
  21. Magnussen GI, Ree Rosnes AK, Shahzidi S, Dong HP, Emilsen E, Engesæter B, Flørenes VA (2012)
    Synthetic retinoid CD437 induces apoptosis and acts synergistically with TRAIL receptor-2 agonist in malignant melanoma
    Biochem Biophys Res Commun, 420 (3), 516-22
    DOI 10.1016/j.bbrc.2012.03.023, PubMed 22446330
  22. Mattingsdal M, Brown AA, Djurovic S, Sønderby IE, Server A, Melle I, Agartz I, Hovig E, Jensen J, Andreassen OA (2012)
    Pathway analysis of genetic markers associated with a functional MRI faces paradigm implicates polymorphisms in calcium responsive pathways
    Neuroimage, 70, 143-9
    DOI 10.1016/j.neuroimage.2012.12.035, PubMed 23274185
  23. Nakken S, Johansen M, Fillebeen J, Berge OP, Kirkerød H, Jenssen TK, Hovig E (2012)
    CellLineMiner: a knowledge portal for human cell lines
    Bioinformation, 8 (22), 1119-22
    DOI 10.6026/97320630081119, PubMed 23251048
  24. Namløs HM, Kresse SH, Müller CR, Henriksen J, Holdhus R, Sæter G, Bruland OS, Bjerkehagen B, Steen VM, Myklebost O (2012)
    Global gene expression profiling of human osteosarcomas reveals metastasis-associated chemokine pattern
    Sarcoma, 2012, 639038
    DOI 10.1155/2012/639038, PubMed 22518090
  25. Namløs HM, Meza-Zepeda LA, Barøy T, Østensen IH, Kresse SH, Kuijjer ML, Serra M, Bürger H, Cleton-Jansen AM, Myklebost O (2012)
    Modulation of the osteosarcoma expression phenotype by microRNAs
    PLoS One, 7 (10), e48086
    DOI 10.1371/journal.pone.0048086, PubMed 23133552
  26. Ohnstad HO, Castro R, Sun J, Heintz KM, Vassilev LT, Bjerkehagen B, Kresse SH, Meza-Zepeda LA, Myklebost O (2012)
    Correlation of TP53 and MDM2 genotypes with response to therapy in sarcoma
    Cancer, 119 (5), 1013-22
    DOI 10.1002/cncr.27837, PubMed 23165797
  27. Ree AH (2012)
    Individualised treatment of metastatic cancer
    Tidsskr Nor Laegeforen, 132 (21), 2358-9
    DOI 10.4045/tidsskr.12.1130, PubMed 23160572
  28. Ree AH, Kristensen AT, Saelen MG, de Wijn R, Edvardsen H, Jovanovic J, Abrahamsen TW, Dueland S, Flatmark K (2012)
    Tumor phosphatidylinositol-3-kinase signaling and development of metastatic disease in locally advanced rectal cancer
    PLoS One, 7 (11), e50806
    DOI 10.1371/journal.pone.0050806, PubMed 23226389
  29. Reikvam DH, Derrien M, Islam R, Erofeev A, Grcic V, Sandvik A, Gaustad P, Meza-Zepeda LA, Jahnsen FL, Smidt H, Johansen FE (2012)
    Epithelial-microbial crosstalk in polymeric Ig receptor deficient mice
    Eur J Immunol, 42 (11), 2959-70
    DOI 10.1002/eji.201242543, PubMed 22865203
  30. Saelen MG, Ree AH, Kristian A, Fleten KG, Furre T, Hektoen HH, Flatmark K (2012)
    Radiosensitization by the histone deacetylase inhibitor vorinostat under hypoxia and with capecitabine in experimental colorectal carcinoma
    Radiat Oncol, 7, 165
    DOI 10.1186/1748-717X-7-165, PubMed 23017053
  31. Schee K, Boye K, Abrahamsen TW, Fodstad Ø, Flatmark K (2012)
    Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer
    BMC Cancer, 12, 505
    DOI 10.1186/1471-2407-12-505, PubMed 23121918
  32. Schee K, Flatmark K, Holm R, Boye K, Paus E (2012)
    Investigation of nonspecific cross-reacting antigen 2 as a prognostic biomarker in bone marrow plasma from colorectal cancer patients (vol 33, pg 73, 2012)
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