Developing Precision Medicine Approaches: To create personalized treatment plans for patients with Alzheimer's disease (AD), Parkinson's disease (PD), and Dementia with Lewy Bodies (DLB) by integrating genetic, biomarker, and clinical data.
Innovative Therapeutic Strategies: To identify new drug targets and therapeutic interventions aimed at enhancing cellular clearance mechanisms in neurodegenerative diseases.
Early Diagnosis and Prevention: To develop reliable biomarkers and advanced imaging techniques for early diagnosis and potential prevention strategies for neurodegenerative diseases.
Understanding Disease Mechanisms: To elucidate the molecular and cellular pathways involved in the onset and progression of neurodegenerative diseases, with an emphasis on translational research.
Enhancing Patient Outcomes: To improve the quality of life and clinical outcomes for patients through the development of novel diagnostic tools and therapeutic strategies.
Collaborative Research Networks: To establish and expand collaborative research networks between different institutions and disciplines, fostering a multidisciplinary approach to tackling neurodegeneration.
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Bahrami S, Nordengen K, Rokicki J, Shadrin AA, Rahman Z, Smeland OB, Jaholkowski PP, Parker N, Parekh P, O'Connell KS, Elvsåshagen T, Toft M, Djurovic S, Dale AM, Westlye LT, Kaufmann T, Andreassen OA(2024) The genetic landscape of basal ganglia and implications for common brain disorders Nat Commun, 15(1), 8476 DOI 10.1038/s41467-024-52583-0, PubMed 39353893
Jaholkowski P, Bahrami S, Fominykh V, Hindley GFL, Tesfaye M, Parekh P, Parker N, Filiz TT, Nordengen K, Hagen E, Koch E, Bakken NR, Frei E, Birkenæs V, Rahman Z, Frei O, Haavik J, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Shadrin AA, Andreassen OA(2024) Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development Neurobiol Dis, 203, 106750 DOI 10.1016/j.nbd.2024.106750, PubMed 39608471
