Kaja Nordengen

  • Group leader, Consultant; MD, PhD
 

Publications 2024

Bahrami S, Nordengen K, Rokicki J, Shadrin AA, Rahman Z, Smeland OB, Jaholkowski PP, Parker N, Parekh P, O'Connell KS, Elvsåshagen T, Toft M, Djurovic S, Dale AM, Westlye LT, Kaufmann T, Andreassen OA (2024)
The genetic landscape of basal ganglia and implications for common brain disorders
Nat Commun, 15 (1), 8476
DOI 10.1038/s41467-024-52583-0, PubMed 39353893

Knudtzon SL, Nordengen K, Grøntvedt GR, Jarholm J, Eliassen IV, Selnes P, Pålhaugen L, Espenes J, Gísladóttir B, Waterloo K, Fladby T, Kirsebom BE (2024)
Age-adjusted CSF t-tau and NfL do not improve diagnostic accuracy for prodromal Alzheimer's disease
Neurobiol Aging, 141, 74-84
DOI 10.1016/j.neurobiolaging.2024.05.016, PubMed 38838442

Nordengen K, Cappelletti C, Bahrami S, Frei O, Pihlstrøm L, Henriksen SP, Geut H, Rozemuller AJM, van de Berg WDJ, Andreassen OA, Toft M (2024)
Pleiotropy with sex-specific traits reveals genetic aspects of sex differences in Parkinson's disease
Brain, 147 (3), 858-870
DOI 10.1093/brain/awad297, PubMed 37671566

Nordengen K, Morland C (2024)
From Synaptic Physiology to Synaptic Pathology: The Enigma of α-Synuclein
Int J Mol Sci, 25 (2)
DOI 10.3390/ijms25020986, PubMed 38256059

Seferi G, Mjønes HS, Havik M, Reiersen H, Dalen KT, Nordengen K, Morland C (2024)
Distribution of lipid droplets in hippocampal neurons and microglia: impact of diabetes and exercise
Life Sci Alliance, 7 (10)
DOI 10.26508/lsa.202302239, PubMed 39117458

Publications 2023

Jarholm JA, Bjørnerud A, Dalaker TO, Akhavi MS, Kirsebom BE, Pålhaugen L, Nordengen K, Grøntvedt GR, Nakling A, Kalheim LF, Almdahl IS, Tecelão S, Fladby T, Selnes P (2023)
Medial Temporal Lobe Atrophy in Predementia Alzheimer's Disease: A Longitudinal Multi-Site Study Comparing Staging and A/T/N in a Clinical Research Cohort
J Alzheimers Dis, 94 (1), 259-279
DOI 10.3233/JAD-221274, PubMed 37248900

Nordengen K, Kirsebom BE, Richter G, Pålhaugen L, Gísladóttir B, Siafarikas N, Nakling A, Rongve A, Bråthen G, Grøntvedt GR, Gonzalez F, Waterloo K, Sharma K, Karikari T, Vromen EM, Tijms BM, Visser PJ, Selnes P, Kramberger MG, Winblad B, Blennow K, Fladby T (2023)
Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer's disease
J Neuroinflammation, 20 (1), 298
DOI 10.1186/s12974-023-02973-w, PubMed 38093257

Publications 2022

Bahrami S, Nordengen K, Shadrin AA, Frei O, van der Meer D, Dale AM, Westlye LT, Andreassen OA, Kaufmann T (2022)
Distributed genetic architecture across the hippocampal formation implies common neuropathology across brain disorders
Nat Commun, 13 (1), 3436
DOI 10.1038/s41467-022-31086-w, PubMed 35705537

Kirsebom BE, Richter G, Nordengen K, Aarsland D, Bråthen G, Tijms BM, Visser PJ, Nilsson J, Selnes P, Kramberger MG, Winblad B, Waterloo K, Gísladóttir B, Blennow K, Fladby T (2022)
Stable cerebrospinal fluid neurogranin and β-site amyloid precursor protein cleaving enzyme 1 levels differentiate predementia Alzheimer's disease patients
Brain Commun, 4 (5), fcac244
DOI 10.1093/braincomms/fcac244, PubMed 36262371

Morland C, Nordengen K (2022)
N-Acetyl-Aspartyl-Glutamate in Brain Health and Disease
Int J Mol Sci, 23 (3)
DOI 10.3390/ijms23031268, PubMed 35163193

Nordengen K, Pålhaugen L, Bettella F, Bahrami S, Selnes P, Jarholm J, Athanasiu L, Shadrin A, Andreassen OA, Fladby T (2022)
Phenotype-informed polygenic risk scores are associated with worse outcome in individuals at risk of Alzheimer's disease
Alzheimers Dement (Amst), 14 (1), e12350
DOI 10.1002/dad2.12350, PubMed 35991219

Roaldsen MB, Eltoft A, Wilsgaard T, Christensen H, Engelter ST, Indredavik B, Jatužis D, Karelis G, Kõrv J, Lundström E, Petersson J, Putaala J, Søyland MH, Tveiten A, Bivard A, Johnsen SH, Mazya MV, Werring DJ, Wu TY, De Marchis GM, Robinson TG, Mathiesen EB, TWIST Investigators (2022)
Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST): a multicentre, open-label, randomised controlled trial
Lancet Neurol, 22 (2), 117-126
DOI 10.1016/S1474-4422(22)00484-7, PubMed 36549308

Publications 2021

Sletteberg R, Nordengen K, Sorteberg W, Jacobsen EA (2021)
A woman in her seventies with acute onset of blindness
Tidsskr Nor Laegeforen, 141
DOI 10.4045/tidsskr.20.1034, PubMed 34597004

Sletteberg R, Nordengen K, Sorteberg W, Jacobsen EA (2021)
A woman in her 70s with acute blindness
Tidsskr. Nor. Laegeforen., 141 (13), 1281-1284

Publications 2020

Qureshi T, Bjørkmo M, Nordengen K, Gundersen V, Utheim TP, Watne LO, Storm-Mathisen J, Hassel B, Chaudhry FA (2020)
Slc38a1 Conveys Astroglia-Derived Glutamine into GABAergic Interneurons for Neurotransmitter GABA Synthesis
Cells, 9 (7)
DOI 10.3390/cells9071686, PubMed 32668809

Publications 2019

Nordengen K, Kirsebom BE, Henjum K, Selnes P, Gísladóttir B, Wettergreen M, Torsetnes SB, Grøntvedt GR, Waterloo KK, Aarsland D, Nilsson LNG, Fladby T (2019)
Glial activation and inflammation along the Alzheimer's disease continuum
J Neuroinflammation, 16 (1), 46
DOI 10.1186/s12974-019-1399-2, PubMed 30791945

Publications 2018

Kirsebom BE, Nordengen K, Selnes P, Waterloo K, Torsetnes SB, Gísladóttir B, Brix B, Vanmechelen E, Bråthen G, Hessen E, Aarsland D, Fladby T (2018)
Cerebrospinal fluid neurogranin/β-site APP-cleaving enzyme 1 predicts cognitive decline in preclinical Alzheimer's disease
Alzheimers Dement (N Y), 4, 617-627
DOI 10.1016/j.trci.2018.10.003, PubMed 30519627

Publications 2017

Nordengen K (2017)
[Not Available]
Tidsskr Nor Laegeforen, 137 (16)
DOI 10.4045/tidsskr.17.0311, PubMed 28871766

Nordengen K (2017)
Diving for seahorses
Tidsskr. Nor. Laegeforen., 137 (5), 384
DOI 10.4045/tidsskr.16.1122

Nordengen K (2017)
OUR INCREDIBLE BRAIN A nervous story about our dynamic and portable brain
Tidsskr. Nor. Laegeforen., 137 (16), 1229

Publications 2013

Nordengen K, Heuser C, Rinholm JE, Matalon R, Gundersen V (2013)
Localisation of N-acetylaspartate in oligodendrocytes/myelin
Brain Struct Funct, 220 (2), 899-917
DOI 10.1007/s00429-013-0691-7, PubMed 24379086

Publications 2012

Morland C, Nordengen K, Gundersen V (2012)
Valproate causes reduction of the excitatory amino acid aspartate in nerve terminals
Neurosci Lett, 527 (2), 100-4
DOI 10.1016/j.neulet.2012.08.042, PubMed 22963924

Morland C, Nordengen K, Larsson M, Prolo LM, Farzampour Z, Reimer RJ, Gundersen V (2012)
Vesicular uptake and exocytosis of L-aspartate is independent of sialin
FASEB J, 27 (3), 1264-74
DOI 10.1096/fj.12-206300, PubMed 23221336

Publications 2008

Holten AT, Morland C, Nordengen K, Gundersen V (2008)
Vesicular Release of L- and D-Aspartate from Hippocampal Nerve Termi- nals: Immunogold Evidence
The Open Neuroscience Journal, 2, 51-58
PublikaID 505

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