Einar Hopp

  • Consultant radiologist; MD, PhD

Einar Hopp, MD, PhD is the leader for the research group Non-invasive Cardiac Imaging.

Non-invasive cardiac imaging includes nuclear medicine techniques like SPECT and PET/CT, Computed tomography (CT) and magnetic resonance imaging (MRI). Measurement of metabolism, oxygen demand and perfusion is ever evolving in nuclear medicine, and novel pharmacological agents cause new possibilities and method refinement. Cardiac CT experiencex hardware advances increasing uptake speed and decreasing radiation.

Analytic advances include dynamic imaging with functional assessment, and more complex algorithms providing flow estimation. Trends in cardiac MRI include regional function with 4D motion and deformation analyses, and detailed tissue characterization through direct T1, T2 and T2* measurement.

Members of the group participate in different clinical projects, providing primary and secondary end points on ischemic heart disease, cardiomyopathies, valvular heart disease and severe heart failure.
Imaging studies focus on method development, validation and refinement.

 

Publications 2021

Broch K, Anstensrud AK, Woxholt S, Sharma K, Tollefsen IM, Bendz B, Aakhus S, Ueland T, Amundsen BH, Damas JK, Berg ES, Bjorkelund E, Bendz C, Hopp E, Kleveland O, Stensaeth KH, Opdahl A, Klow NE, Seljeflot I, Andersen GO, Wiseth R, Aukrust P, Gullestad L (2021)
Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction
J. Am. Coll. Cardiol., 77 (15), 1845-1855
DOI 10.1016/j.jacc.2021.02.049

Degtiarova G, Claus P, Duchenne J, Bogaert J, Nuyts J, Voros G, Willems R, Larsen CK, Aalen JM, Fjeld JG, Stokke C, Hopp E, Smiseth OA, Voigt JU, Gheysens O (2021)
Left ventricular regional glucose metabolism in combination with septal scar extent identifies CRT responders
Eur. J. Nucl. Med. Mol. Imaging, 48 (8), 2437-2446
DOI 10.1007/s00259-020-05161-7

Lie OH, Klaboe LG, Dejgaard LA, Skjolsvik ET, Grimsmo J, Bosse G, Hopp E, Edvardsen T, Haugaa KH (2021)
Cardiac Phenotypes and Markers of Adverse Outcome in Elite Athletes With Ventricular Arrhythmias
JACC-Cardiovasc. Imag., 14 (1), 148-158
DOI 10.1016/j.jcmg.2020.07.039

Sletten OJ, Aalen JM, Izci H, Duchenne J, Remme EW, Larsen CK, Hopp E, Galli E, Sirnes PA, Kongsgard E, Donal E, Voigt JU, Smiseth OA, Skulstad H (2021)
Lateral Wall Dysfunction Signals Onset of Progressive Heart Failure in Left Bundle Branch Block
JACC-Cardiovasc. Imag., 14 (11), 2059-2069
DOI 10.1016/j.jcmg.2021.04.017

Suther KR, de Lange C, Brun H, Svendsmark R, Nguyen B, Larsen S, Smevik B, Fiane AE, Lindbergh HL, Hopp E (2021)
3.0T MR Coronary Angiography after Arterial Switch Operation for Transposition of The Great Arteries-Gd-FLASH Versus Non-Enhanced SSFP. A Feasibility Study
Congenit. Heart Dis., 16 (2), 107-121
DOI 10.32604/CHD.2021.014164

Aabel EW, Chivulescu M, Dejgaard LA, Ribe M, Gjertsen E, Hopp E, Hunt TE, Lie OH, Haugaa KH (2021)
Tricuspid Annulus Disjunction Novel Findings by Cardiac Magnetic Resonance in Patients With Mitral Annulus Disjunction
JACC-Cardiovasc. Imag., 14 (8), 1535-1543
DOI 10.1016/j.jcmg.2021.01.028

Publications 2020

Aulokken TM, Parkar AP, Markussen TV, Ashraf H, Mynarek GK, Nes H, Muller F, Schubert M, Jorgensen A, Blomberg SM, Bjornerheim R, Klow NE, Hopp E (2020)
Imaging of patients with COVID-19
Tidsskr. Nor. Laegeforen., 140 (8), 756-760

Duchenne J, Aalen JM, Cvijic M, Larsen CK, Galli E, Bezy S, Beela AS, Unlu S, Pagourelias ED, Winter S, Hopp E, Kongsgard E, Donal E, Fehske W, Smiseth OA, Voigt JU (2020)
Acute redistribution of regional left ventricular work by cardiac resynchronization therapy determines long-term remodelling
Eur. Heart J.-Cardiovasc. Imaging, 21 (6), 619-628
DOI 10.1093/ehjci/jeaa003

Falkenberg-Jensen B, Jablonski GE, Silvola JT, Kristiansen JF, Hopp E (2020)
CT imaging of the Eustachian tube using focal contrast medium administration: a feasibility study in humans
Acta Radiol. Open, 9 (1), 2058460119900435
DOI 10.1177/2058460119900435

Larsen CK, Aalen JM, Stokke C, Fjeld JG, Kongsgaard E, Duchenne J, Degtiarova G, Gheysens O, Voigt JU, Smiseth OA, Hopp E (2020)
Regional myocardial work by cardiac magnetic resonance and non-invasive left ventricular pressure: a feasibility study in left bundle branch block
Eur. Heart J.-Cardiovasc. Imaging, 21 (2), 143-153
DOI 10.1093/ehjci/jez231

Ross S, Nestaas E, Kongsgaard E, Odland HH, Haland TF, Hopp E, Haugaa KH, Edvardsen T (2020)
Septal contraction predicts acute haemodynamic improvement and paced QRS width reduction in cardiac resynchronization therapy
Eur. Heart J.-Cardiovasc. Imaging, 21 (8), 845-852
DOI 10.1093/ehjci/jez315

Aalen JM, Donal E, Larsen CK, Duchenne J, Lederlin M, Cvijic M, Hubert A, Voros G, Leclercq C, Bogaert J, Hopp E, Fjeld JG, Penicka M, Linde C, Aalen OO, Kongsgard E, Galli E, Voigt JU, Smiseth OA (2020)
Imaging predictors of response to cardiac resynchronization therapy: left ventricular work asymmetry by echocardiography and septal viability by cardiac magnetic resonance
Eur. Heart J., 41 (39), 3813-3823
DOI 10.1093/eurheartj/ehaa603

Publications 2019

Anstensrud AK, Woxholt S, Sharma K, Broch K, Bendz B, Aakhus S, Ueland T, Amundsen BH, Damas JK, Hopp E, Kleveland O, Stensaeth KH, Opdahl A, Klow NE, Seljeflot I, Andersen GO, Wiseth R, Aukrust P, Gullestad L (2019)
Rationale for the ASSAIL-MI-trial: a randomised controlled trial designed to assess the effect of tocilizumab on myocardial salvage in patients with acute ST-elevation myocardial infarction (STEMI)
Open Heart, 6 (2), UNSP e001108
DOI 10.1136/openhrt-2019-001108

Babic A, Odland HH, Lyseggen E, Holm T, Ross S, Hopp E, Haugaa KH, Kongsgard E, Edvardsen T, Gerard O, Samset E (2019)
An image fusion tool for echo-guided left ventricular lead placement in cardiac resynchronization therapy: Performance and workflow integration analysis
Echocardiography-J. Cardiovasc. Ultrasound Allied Tech., 36 (10), 1834-1845
DOI 10.1111/echo.14483

Scheirlynck E, Dejgaard LA, Skjolsvik E, Lie OH, Motoc A, Hopp E, Tanaka K, Ueland T, Ribe M, Collet C, Edvardsen T, Droogmans S, Cosyns B, Haugaa KH (2019)
Increased levels of sST2 in patients with mitral annulus disjunction and ventricular arrhythmias
Open Heart, 6 (1), UNSP e001016
DOI 10.1136/openhrt-2019-001016

Suther KR, Hopp E, Geier O, Brun H, Nguyen B, Tomterstad AH, Smevik B, Fiane AE, Lindberg HL, de Lange C (2019)
Diffuse myocardial fibrosis in adolescents operated with arterial switch for transposition of the great arteries - A CMR study
Int. J. Cardiol., 276, 100-106
DOI 10.1016/j.ijcard.2018.11.107

Aalen JM, Remme EW, Larsen CK, Andersen OS, Krogh M, Duchenne J, Hopp E, Ross S, Beela AS, Kongsgaard E, Bergsland J, Odland HH, Skulstad H, Opdahl A, Voigt JU, Smiseth OA (2019)
Mechanism of Abnormal Septal Motion in Left Bundle Branch Block Role of Left Ventricular Wall Interactions and Myocardial Scar
JACC-Cardiovasc. Imag., 12 (12), 2402-2413
DOI 10.1016/j.jcmg.2018.11.030

Publications 2018

Abildgaard A, Roterud H, Beyer M, Hopp E, Bjornerud A, Smith HJ, Sakinis T (2018)
Will radiologists be replaced by artificial intelligence?
Tidsskr. Nor. Laegeforen., 138 (17), 1610-1612

Balaban G, Finsberg H, Funke S, Haland TF, Hopp E, Sundnes J, Wall S, Rognes ME (2018)
In vivo estimation of elastic heterogeneity in an infarcted human heart
Biomech. Model. Mechanobiol., 17 (5), 1317-1329
DOI 10.1007/s10237-018-1028-5

Dejgaard LA, Skjolsvik ET, Lie OH, Ribe M, Stokke MK, Hegbom F, Scheirlynck ES, Gjertsen E, Andresen K, Helle-Valle TM, Hopp E, Edvardsen T, Haugaa KH (2018)
The Mitral Annulus Disjunction Arrhythmic Syndrome
J. Am. Coll. Cardiol., 72 (14), 1600-1609
DOI 10.1016/j.jacc.2018.07.070

Falkenberg-Jensen B, Heimdal KR, Hogevold HE, Jablonski GE, Due-Tonnessen BJ, Hopp E (2018)
Abnormally Wide Eustachian Tubes Involving the Sphenoid Bone: A Collection
Laryngoscope Investig. Otol., 3 (3), 214-217
DOI 10.1002/lio2.158

Falkenberg-Jensen B, Hopp E, Jablonski GE, Pripp AH, Silvola JT (2018)
The cartilaginous Eustachian tube: Reliable CT measurement and impact of the length
Am. J. Otolaryngol., 39 (4), 436-440
DOI 10.1016/j.amjoto.2018.04.010

Hopp E, Skretteberg PT, Landa M, Lyseggen E, Tomterstad AH, Pedersen HK (2018)
"It is important for the patient to carry with them the provided pacemaker card at any time"
Tidsskr. Nor. Laegeforen., 138 (1), 9-10

Ross S, Odland HH, Aranda A, Edvardsen T, Gammelsrud LO, Haland TF, Cornelussen R, Hopp E, Kongsgaard E (2018)
Cardiac resynchronization therapy when no lateral pacing option exists: vectorcardiographic guided non-lateral left ventricular lead placement predicts acute hemodynamic response
Europace, 20 (8), 1294-1302
DOI 10.1093/europace/eux249

Ross S, Odland HH, Fischer T, Edvardsen T, Gammelsrud LO, Haland TF, Cornelussen R, Hopp E, Kongsgaard E (2018)
Contractility surrogates derived from three-dimensional lead motion analysis and prediction of acute haemodynamic response to CRT
Open Heart, 5 (2), UNSP e000874
DOI 10.1136/openhrt-2018-000874

Suther KR, Hopp E, Smevik B, Fiane AE, Lindberg HL, Larsen S, Lange C (2018)
Can visual analogue scale be used in radiologic subjective image quality assessment?
Pediatr. Radiol., 48 (11), 1567-1575
DOI 10.1007/s00247-018-4187-8

Publications 2017

Hopp E, Skretteberg PT, Landa M, Lyseggen E, Tomterstad AH, Pedersen HK (2017)
MRI examination of patients with pacemaker or implanted cardiac arrest
Tidsskr. Nor. Laegeforen., 137 (21), 1668-1669

Nestaas E, Shih JY, Smedsrud MK, Gjesdal O, Hopp E, Haugaa KH, Edvardsen T (2017)
Comparison of Electrocardiography Markers and Speckle Tracking Echocardiography for Assessment of Left Ventricular Myocardial Scar Burden in Patients With Previous Myocardial Infarction
Am. J. Cardiol., 119 (9), 1307-1312
DOI 10.1016/j.amjcard.2017.01.020

Saberniak J, Leren IS, Haland TF, Beitnes JO, Hopp E, Borgquist R, Edvardsen T, Haugaa KH (2017)
Comparison of patients with early-phase arrhythmogenic right ventricular cardiomyopathy and right ventricular outflow tract ventricular tachycardia
Eur. Heart J.-Cardiovasc. Imaging, 18 (1), 62-69
DOI 10.1093/ehjci/jew014

Publications 2016

Broch K, Urheim S, Lonnebakken MT, Stueflotten W, Massey R, Fossa K, Hopp E, Aakhus S, Gullestad L (2016)
Controlled release metoprolol for aortic regurgitation: a randomised clinical trial
Heart, 102 (3), 191-197
DOI 10.1136/heartjnl-2015-308416

Broch K, Urheim S, Massey R, Stueflotten W, Fossa K, Hopp E, Aakhus S, Gullestad L (2016)
Exercise capacity and peak oxygen consumption in asymptomatic patients with chronic aortic regurgitation
Int. J. Cardiol., 223, 688-692
DOI 10.1016/j.ijcard.2016.08.237

Falkenberg-Jensen B, Silvola J, Laurvik H, Lervik A, Kristiansen JF, Jablonski G, Hopp E (2016)
CT Imaging of the Eustachian Tube Using Focal Contrast Medium Administration: A Feasibility Study
Larynscope Investig. Otol., 1 (4), 83-87
DOI 10.1002/lio2.24

Haland TF, Almaas VM, Hasselberg NE, Saberniak J, Leren IS, Hopp E, Edvardsen T, Haugaa KH (2016)
Strain echocardiography is related to fibrosis and ventricular arrhythmias in hypertrophic cardiomyopathy
Eur. Heart J.-Cardiovasc. Imaging, 17 (6), 613-621
DOI 10.1093/ehjci/jew005

Noonan KY, Russo J, Shen J, Rehm H, Halbach S, Hopp E, Noon S, Hoover J, Eskey C, Saunders JE (2016)
CDH23 Related Hearing Loss: A New Genetic Risk Factor for Semicircular Canal Dehiscence?
Otol. Neurotol., 37 (10), 1583-1588
DOI 10.1097/MAO.0000000000001210

Nordfalk KF, Rasmussen K, Hopp E, Bunne M, Silvola JT, Jablonski GE (2016)
Insertion Depth in Cochlear Implantation and Outcome in Residual Hearing and Vestibular Function
Ear Hear., 37 (2), e129-e137
DOI 10.1097/AUD.0000000000000241

Prescott TE, Kulseth MA, Heimdal KR, Stadheim B, Hopp E, Gambin T, Akdemir ZHC, Jhangiani SN, Muzny DM, Gibbs RA, Lupski JR, Stray-Pedersen A (2016)
Two male sibs with severe micrognathia and a missense variant in MED12
Eur. J. Med. Genet., 59 (8), 367-372
DOI 10.1016/j.ejmg.2016.06.001

Publications 2015

Broch K, Andreassen AK, Hopp E, Leren TP, Scott H, Muller F, Aakhus S, Gullestad L (2015)
Results of comprehensive diagnostic work-up in 'idiopathic' dilated cardiomyopathy
Open Heart, 2 (1), UNSP e000271
DOI 10.1136/openhrt-2015-000271

Broch K, Murbraech K, Andreassen AK, Hopp E, Aakhus S, Gullestad L (2015)
Contemporary Outcome in Patients With Idiopathic Dilated Cardiomyopathy
Am. J. Cardiol., 116 (6), 952-959
DOI 10.1016/j.amjcard.2015.06.022

Publications 2014

Gjesdal O, Almeida ALC, Hopp E, Beitnes JO, Lunde K, Smith HJR, Lima JAC, Edvardsen T (2014)
Long Axis Strain by MRI and Echocardiography in a Postmyocardial Infarct Population
J. Magn. Reson. Imaging, 40 (5), 1247-1251
DOI 10.1002/jmri.24485

Nordfalk KF, Rasmussen K, Hopp E, Greisiger R, Jablonski GE (2014)
Scalar position in cochlear implant surgery and outcome in residual hearing and the vestibular system
Int. J. Audiol., 53 (2), 121-127
DOI 10.3109/14992027.2013.854413

Publications 2013

Hopp E, Bjornerud A, Lunde K, Solheim S, Aakhus S, Arnesen H, Forfang K, Edvardsen T, Smith HJ (2013)
Perfusion MRI at rest in subacute and chronic myocardial infarct
Acta Radiol., 54 (4), 401-411
DOI 10.1177/0284185113475605

Publications 2011

Hopp E, Lunde K, Solheim S, Aakhus S, Arnesen H, Forfang K, Edvardsen T, Smith HJ (2011)
Regional myocardial function after intracoronary bone marrow cell injection in reperfused anterior wall infarction - a cardiovascular magnetic resonance tagging study
J. Cardiov. Magn. Reson., 13, 22
DOI 10.1186/1532-429X-13-22

Publications 2009

Beitnes JO, Hopp E, Lunde K, Solheim S, Arnesen H, Brinchmann JE, Forfang K, Aakhus S (2009)
Long-term results after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: the ASTAMI randomised, controlled study
Heart, 95 (24), 1983-1989
DOI 10.1136/hrt.2009.178913

Gjesdal O, Vartdal T, Hopp E, Lunde K, Brunvand H, Smith HJ, Edvardsen T (2009)
Left Ventricle Longitudinal Deformation Assessment by Mitral Annulus Displacement or Global Longitudinal Strain in Chronic Ischemic Heart Disease: Are They Interchangeable?
J. Am. Soc. Echocardiogr., 22 (7), 823-830
DOI 10.1016/j.echo.2009.04.023

Publications 2008

Gjesdal O, Helle-Valle T, Hopp E, Lunde K, Vandal T, Aakhus S, Smith HJ, Ihlen H, Edvardsen T (2008)
Noninvasive Separation of Large, Medium, and Small Myocardial Infarcts in Survivors of Reperfused ST-Elevation Myocardial Infarction A Comprehensive Tissue Doppler and Speckle-Tracking Echocardiography Study
Circ.-Cardiovasc. Imaging, 1 (3), 189-196
DOI 10.1161/CIRCIMAGING.108.784900

Wyller VB, Saul JP, Barbieri R, de Lange C, Hopp E, Norum IB, Thaulow E (2008)
Autonomic Heart Rate Control at Rest and During Unloading of the Right Ventricle in Repaired Tetralogy of Fallot in Adolescents
Am. J. Cardiol., 102 (8), 1085-1089
DOI 10.1016/j.amjcard.2008.05.065

Publications 2007

Gjesdal O, Hopp E, Vartdal T, Lunde K, Helle-Valle T, Aakhus S, Smith HJ, Ihlen H, Edvardsen T (2007)
Global longitudinal strain measured by two-dimensional speckle tracking echocardiography is closely related to myocardial infarct size in chronic ischaemic heart disease
Clin. Sci., 113 (5-6), 287-296
DOI 10.1042/CS20070066

Publications 2006

Lunde K, Solheim S, Aakhus S, Arnesen H, Abdelnoor M, Egeland T, Endresen K, Ilebekk A, Mangschau A, Fjeld JG, Smith HJ, Taraldsrud E, Grogaard HK, Bjornerheim R, Brekke M, Muller C, Hopp E, Ragnarsson A, Brinchmann JE, Forfang K (2006)
Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction
N. Engl. J. Med., 355 (12), 1199-1209
DOI 10.1056/NEJMoa055706

Ruud E, Holmstrom H, Hopp E, Wesenberg F (2006)
Central line-associated venous late effects in children without prior history of thrombosis
Acta Paediatr., 95 (9), 1060-1065
DOI 10.1080/08035250500499457

Publications 2005

Rosseland LA, Bentsen G, Hopp E, Refsum S, Breivik H (2005)
Monitoring urinary bladder volume and detecting post-operative urinary retention in children with an ultrasound scanner
Acta Anaesthesiol. Scand., 49 (10), 1456-1459
DOI 10.1111/j.1399-6576.2005.00817.x

Publications 2004

Hopp E, Mortensen B, Kolbenstvedt A (2004)
Mylohyoid herniation of the sublingual gland diagnosed by magnetic resonance imaging
Dentomaxillofac. Radiol., 33 (5), 351-353
DOI 10.1259/dmfr/31454077