Britt Nakken

  • Principal Investigator/Researcher; PhD
 

Publications 2021

Szabó K, Jámbor I, Szántó A, Horváth IF, Tarr T, Nakken B, Szodoray P, Papp G (2021)
The Imbalance of Circulating Follicular T Helper Cell Subsets in Primary Sjögren's Syndrome Associates With Serological Alterations and Abnormal B-Cell Distribution
Front Immunol, 12, 639975
DOI 10.3389/fimmu.2021.639975, PubMed 33815392

Publications 2019

Daws MR, Nakken B, Lobato-Pascual A, Josien R, Dissen E, Fossum S (2019)
Dendritic Cell Activating Receptor 1 (DCAR1) Associates With FcεRIγ and Is Expressed by Myeloid Cell Subsets in the Rat
Front Immunol, 10, 1060
DOI 10.3389/fimmu.2019.01060, PubMed 31134097

Publications 2017

Nakken B, Papp G, Bosnes V, Zeher M, Nagy G, Szodoray P (2017)
Biomarkers for rheumatoid arthritis: From molecular processes to diagnostic applications-current concepts and future perspectives
Immunol Lett, 189, 13-18
DOI 10.1016/j.imlet.2017.05.010, PubMed 28526580

Papp G, Boros P, Nakken B, Szodoray P, Zeher M (2017)
Regulatory immune cells and functions in autoimmunity and transplantation immunology
Autoimmun Rev, 16 (5), 435-444
DOI 10.1016/j.autrev.2017.03.011, PubMed 28286106

Zeher M, Papp G, Nakken B, Szodoray P (2017)
Hematopoietic stem cell transplantation in autoimmune disorders: From immune-regulatory processes to clinical implications
Autoimmun Rev, 16 (8), 817-825
DOI 10.1016/j.autrev.2017.05.020, PubMed 28572052

Publications 2016

Szodoray P, Stanford SM, Molberg Ø, Munthe LA, Bottini N, Nakken B (2016)
T-helper signals restore B-cell receptor signaling in autoreactive anergic B cells by upregulating CD45 phosphatase activity
J Allergy Clin Immunol, 138 (3), 839-851.e8
DOI 10.1016/j.jaci.2016.01.035, PubMed 27056269

Publications 2015

Nagy G, Huszthy PC, Fossum E, Konttinen Y, Nakken B, Szodoray P (2015)
Selected Aspects in the Pathogenesis of Autoimmune Diseases
Mediators Inflamm, 2015, 351732
DOI 10.1155/2015/351732, PubMed 26300591

Nakken B, Bodolay E, Szodoray P (2015)
Cytokine Milieu in Undifferentiated Connective Tissue Disease: a Comprehensive Review
Clin Rev Allergy Immunol, 49 (2), 152-62
DOI 10.1007/s12016-014-8452-9, PubMed 25274451

Nakken B, Nagy G, Huszthy PC, Fossum E, Konttinen Y, Szodoray P (2015)
Inflammatory Mediators in Autoimmunity and Systemic Autoimmune Diseases
Mediators Inflamm, 2015, 878712
DOI 10.1155/2015/878712, PubMed 26346773

Publications 2014

Bodolay E, Prohászka Z, Paragh G, Csipő I, Nagy G, Laczik R, Demeter N, Zöld E, Nakken B, Szegedi G, Szodoray P (2014)
Increased levels of anti-heat-shock protein 60 (anti-Hsp60) indicate endothelial dysfunction, atherosclerosis and cardiovascular diseases in patients with mixed connective tissue disease
Immunol Res, 60 (1), 50-9
DOI 10.1007/s12026-014-8552-x, PubMed 24838263

Szodoray P, Hajas A, Toth L, Szakall S, Nakken B, Soltesz P, Bodolay E (2014)
The beneficial effect of plasmapheresis in mixed connective tissue disease with coexisting antiphospholipid syndrome
Lupus, 23 (10), 1079-84
DOI 10.1177/0961203314533602, PubMed 24795068

Zold E, Bodolay E, Dezső B, Soos G, Nakken B, Szodoray P (2014)
Mixed connective tissue disease associated with autoimmune hepatitis and pulmonary fibrosis
Isr Med Assoc J, 16 (11), 733-4
PubMed 25558707

Publications 2013

Hajas A, Barath S, Szodoray P, Nakken B, Gogolak P, Szekanecz Z, Zold E, Zeher M, Szegedi G, Bodolay E (2013)
Derailed B cell homeostasis in patients with mixed connective tissue disease
Hum Immunol, 74 (7), 833-41
DOI 10.1016/j.humimm.2013.04.007, PubMed 23608739

Hajas A, Szodoray P, Nakken B, Gaal J, Zöld E, Laczik R, Demeter N, Nagy G, Szekanecz Z, Zeher M, Szegedi G, Bodolay E (2013)
Clinical course, prognosis, and causes of death in mixed connective tissue disease
J Rheumatol, 40 (7), 1134-42
DOI 10.3899/jrheum.121272, PubMed 23637328

Osnes LT, Nakken B, Bodolay E, Szodoray P (2013)
Assessment of intracellular cytokines and regulatory cells in patients with autoimmune diseases and primary immunodeficiencies - novel tool for diagnostics and patient follow-up
Autoimmun Rev, 12 (10), 967-71
DOI 10.1016/j.autrev.2013.02.003, PubMed 23541481

Szodoray P, Nakken B, Barath S, Csipo I, Nagy G, El-Hage F, Osnes LT, Szegedi G, Bodolay E (2013)
Altered Th17 cells and Th17/regulatory T-cell ratios indicate the subsequent conversion from undifferentiated connective tissue disease to definitive systemic autoimmune disorders
Hum Immunol, 74 (12), 1510-8
DOI 10.1016/j.humimm.2013.08.003, PubMed 23974054

Publications 2012

Nakken B, Alex P, Munthe L, Szekanecz Z, Szodoray P (2012)
Immune-regulatory mechanisms in systemic autoimmune and rheumatic diseases
Clin Dev Immunol, 2012, 957151
DOI 10.1155/2012/957151, PubMed 22474487

Szodoray P, Hajas A, Kardos L, Dezso B, Soos G, Zold E, Vegh J, Csipo I, Nakken B, Zeher M, Szegedi G, Bodolay E (2012)
Distinct phenotypes in mixed connective tissue disease: subgroups and survival
Lupus, 21 (13), 1412-22
DOI 10.1177/0961203312456751, PubMed 22864236

Publications 2011

Nakken B, Munthe LA, Konttinen YT, Sandberg AK, Szekanecz Z, Alex P, Szodoray P (2011)
B-cells and their targeting in rheumatoid arthritis--current concepts and future perspectives
Autoimmun Rev, 11 (1), 28-34
DOI 10.1016/j.autrev.2011.06.010, PubMed 21777703

Nakken B, Varga T, Szatmari I, Szeles L, Gyongyosi A, Illarionov PA, Dezso B, Gogolak P, Rajnavolgyi E, Nagy L (2011)
Peroxisome proliferator-activated receptor γ-regulated cathepsin D is required for lipid antigen presentation by dendritic cells
J Immunol, 187 (1), 240-7
DOI 10.4049/jimmunol.1002421, PubMed 21632707

Szodoray P, Varoczy L, Papp G, Barath S, Nakken B, Szegedi G, Zeher M (2011)
Immunological reconstitution after autologous stem cell transplantation in patients with refractory systemic autoimmune diseases
Scand J Rheumatol, 41 (2), 110-5
DOI 10.3109/03009742.2011.606788, PubMed 21936606

Publications 2010

Nakken B, Szodoray P (2010)
Accelerated atherosclerosis in rheumatoid arthritis: rationale for mannose-binding lectins?
J Rheumatol, 37 (3), 482-4
DOI 10.3899/jrheum.091364, PubMed 20197564

Szodoray P, Alex P, Knowlton N, Centola M, Dozmorov I, Csipo I, Nagy AT, Constantin T, Ponyi A, Nakken B, Danko K (2010)
Idiopathic inflammatory myopathies, signified by distinctive peripheral cytokines, chemokines and the TNF family members B-cell activating factor and a proliferation inducing ligand
Rheumatology (Oxford), 49 (10), 1867-77
DOI 10.1093/rheumatology/keq151, PubMed 20591831

Szodoray P, Papp G, Nakken B, Harangi M, Zeher M (2010)
The molecular and clinical rationale of extracorporeal photochemotherapy in autoimmune diseases, malignancies and transplantation
Autoimmun Rev, 9 (6), 459-64
DOI 10.1016/j.autrev.2009.12.011, PubMed 20044039

Zold E, Szodoray P, Nakken B, Barath S, Kappelmayer J, Csathy L, Hajas A, Sipka S, Gyimesi E, Gaal J, Barta Z, Hallay J, Szegedi G, Bodolay E (2010)
Alfacalcidol treatment restores derailed immune-regulation in patients with undifferentiated connective tissue disease
Autoimmun Rev, 10 (3), 155-62
DOI 10.1016/j.autrev.2010.09.018, PubMed 20868777

Publications 2009

Illes A, Varoczy L, Papp G, Wilson PC, Alex P, Jonsson R, Kovacs T, Konttinen YT, Zeher M, Nakken B, Szodoray P (2009)
Aspects of B-cell non-Hodgkin's lymphoma development: a transition from immune-reactivity to malignancy
Scand J Immunol, 69 (5), 387-400
DOI 10.1111/j.1365-3083.2009.02237.x, PubMed 19508370

Szodoray P, Horvath IF, Papp G, Barath S, Gyimesi E, Csathy L, Kappelmayer J, Sipka S, Duttaroy AK, Nakken B, Zeher M (2009)
The immunoregulatory role of vitamins A, D and E in patients with primary Sjogren's syndrome
Rheumatology (Oxford), 49 (2), 211-7
DOI 10.1093/rheumatology/kep374, PubMed 19946023

Szodoray P, Papp G, Horvath IF, Barath S, Sipka S, Nakken B, Zeher M (2009)
Cells with regulatory function of the innate and adaptive immune system in primary Sjögren's syndrome
Clin Exp Immunol, 157 (3), 343-9
DOI 10.1111/j.1365-2249.2009.03966.x, PubMed 19664141

Publications 2008

Duty JA, Szodoray P, Zheng NY, Koelsch KA, Zhang Q, Swiatkowski M, Mathias M, Garman L, Helms C, Nakken B, Smith K, Farris AD, Wilson PC (2008)
Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors
J Exp Med, 206 (1), 139-51
DOI 10.1084/jem.20080611, PubMed 19103878

Szodoray P, Gal I, Barath S, Aleksza M, Horvath IF, Gergely P, Szegedi G, Nakken B, Zeher M (2008)
Immunological alterations in newly diagnosed primary Sjögren's syndrome characterized by skewed peripheral T-cell subsets and inflammatory cytokines
Scand J Rheumatol, 37 (3), 205-12
DOI 10.1080/03009740801910361, PubMed 18465456

Szodoray P, Nakken B, Barath S, Gaal J, Aleksza M, Zeher M, Sipka S, Szilagyi A, Zold E, Szegedi G, Bodolay E (2008)
Progressive divergent shifts in natural and induced T-regulatory cells signify the transition from undifferentiated to definitive connective tissue disease
Int Immunol, 20 (8), 971-9
DOI 10.1093/intimm/dxn056, PubMed 18550583

Szodoray P, Nakken B, Gaal J, Jonsson R, Szegedi A, Zold E, Szegedi G, Brun JG, Gesztelyi R, Zeher M, Bodolay E (2008)
The complex role of vitamin D in autoimmune diseases
Scand J Immunol, 68 (3), 261-9
DOI 10.1111/j.1365-3083.2008.02127.x, PubMed 18510590

Publications 2007

Centola M, Szekanecz Z, Kiss E, Zeher M, Szegedi G, Nakken B, Szodoray P (2007)
Gene expression profiles of systemic lupus erythematosus and rheumatoid arthritis
Expert Rev Clin Immunol, 3 (5), 797-806
DOI 10.1586/1744666X.3.5.797, PubMed 20477029

Szodoray P, Koczok K, Szanto A, Horvath IF, Nakken B, Molnar I, Zeher M (2007)
Autoantibodies to novel membrane and cytosolic antigens of the lachrymal gland in primary Sjögren's syndrome
Clin Rheumatol, 27 (2), 195-9
DOI 10.1007/s10067-007-0678-y, PubMed 17713716

Teague BN, Pan Y, Mudd PA, Nakken B, Zhang Q, Szodoray P, Kim-Howard X, Wilson PC, Farris AD (2007)
Cutting edge: Transitional T3 B cells do not give rise to mature B cells, have undergone selection, and are reduced in murine lupus
J Immunol, 178 (12), 7511-5
DOI 10.4049/jimmunol.178.12.7511, PubMed 17548583

Publications 2006

Centola M, Frank MB, Bolstad AI, Alex P, Szanto A, Zeher M, Hjelmervik TO, Jonsson R, Nakken B, Szegedi G, Szodoray P (2006)
Genome-scale assessment of molecular pathology in systemic autoimmune diseases using microarray technology: a potential breakthrough diagnostic and individualized therapy-design tool
Scand J Immunol, 64 (3), 236-42
DOI 10.1111/j.1365-3083.2006.01802.x, PubMed 16918692

Szodoray P, Alex P, Chappell-Woodward CM, Madland TM, Knowlton N, Dozmorov I, Zeher M, Jarvis JN, Nakken B, Brun JG, Centola M (2006)
Circulating cytokines in Norwegian patients with psoriatic arthritis determined by a multiplex cytokine array system
Rheumatology (Oxford), 46 (3), 417-25
DOI 10.1093/rheumatology/kel306, PubMed 16936328

Szodoray P, Timar O, Veres K, Der H, Szomjak E, Lakos G, Aleksza M, Nakken B, Szegedi G, Soltesz P (2006)
TH1/TH2 imbalance, measured by circulating and intracytoplasmic inflammatory cytokines--immunological alterations in acute coronary syndrome and stable coronary artery disease
Scand J Immunol, 64 (3), 336-44
DOI 10.1111/j.1365-3083.2006.01816.x, PubMed 16918703

Publications 2005

Lindqvist AK, Nakken B, Sundler M, Kjellén P, Jonsson R, Holmdahl R, Skarstein K (2005)
Influence on spontaneous tissue inflammation by the major histocompatibility complex region in the nonobese diabetic mouse
Scand J Immunol, 61 (2), 119-27
DOI 10.1111/j.0300-9475.2005.01550.x, PubMed 15683448

Szodoray P, Alex P, Jonsson MV, Knowlton N, Dozmorov I, Nakken B, Delaleu N, Jonsson R, Centola M (2005)
Distinct profiles of Sjögren's syndrome patients with ectopic salivary gland germinal centers revealed by serum cytokines and BAFF
Clin Immunol, 117 (2), 168-76
DOI 10.1016/j.clim.2005.06.016, PubMed 16126006

Publications 2004

Szodoray P, Alex P, Dandapani V, Nakken B, Pesina J, Kim X, Wallis GL, Wilson PC, Jonsson R, Centola M (2004)
Apoptotic effect of rituximab on peripheral blood B cells in rheumatoid arthritis
Scand J Immunol, 60 (1-2), 209-18
DOI 10.1111/j.0300-9475.2004.01441.x, PubMed 15238091

Publications 2003

Nakken B, Davis KE, Pan ZJ, Bachmann M, Farris AD (2003)
T-helper cell tolerance to ubiquitous nuclear antigens
Scand J Immunol, 58 (5), 478-92
DOI 10.1046/j.1365-3083.2003.01323.x, PubMed 14629620

Szodoray P, Jellestad S, Nakken B, Brun JG, Jonsson R (2003)
Programmed cell death in rheumatoid arthritis peripheral blood T-cell subpopulations determined by laser scanning cytometry
Lab Invest, 83 (12), 1839-48
DOI 10.1097/01.lab.0000101703.80133.99, PubMed 14691302

Publications 2002

Johansson AC, Nakken B, Sundler M, Lindqvist AK, Johannesson M, Alarcón-Riquelme M, Bolstad AI, Humphreys-Beher MG, Jonsson R, Skarstein K, Holmdahl R (2002)
The genetic control of sialadenitis versus arthritis in a NOD.QxB10.Q F2 cross
Eur J Immunol, 32 (1), 243-50
DOI 10.1002/1521-4141(200201)32:1<243::AID-IMMU243>3.0.CO;2-X, PubMed 11782015

Publications 2001

Johansson AC, Sundler M, Kjellén P, Johannesson M, Cook A, Lindqvist AK, Nakken B, Bolstad AI, Jonsson R, Alarcón-Riquelme M, Holmdahl R (2001)
Genetic control of collagen-induced arthritis in a cross with NOD and C57BL/10 mice is dependent on gene regions encoding complement factor 5 and FcgammaRIIb and is not associated with loci controlling diabetes
Eur J Immunol, 31 (6), 1847-56
DOI 10.1002/1521-4141(200106)31:6<1847::aid-immu1847>3.0.co;2-f, PubMed 11433381

Magnusson V, Nakken B, Bolstad AI, Alarcón-Riquelme ME (2001)
Cytokine polymorphisms in systemic lupus erythematosus and Sjögren's syndrome
Scand J Immunol, 54 (1-2), 55-61
DOI 10.1046/j.1365-3083.2001.00965.x, PubMed 11439148

Nakken B, Jonsson R, Bolstad AI (2001)
Polymorphisms of the Ro52 gene associated with anti-Ro 52-kd autoantibodies in patients with primary Sjögren's syndrome
Arthritis Rheum, 44 (3), 638-46
DOI 10.1002/1529-0131(200103)44:3<638::AID-ANR112>3.0.CO;2-J, PubMed 11263778

Nakken B, Jonsson R, Brokstad KA, Omholt K, Nerland AH, Haga HJ, Halse AK (2001)
Associations of MHC class II alleles in Norwegian primary Sjögren's syndrome patients: implications for development of autoantibodies to the Ro52 autoantigen
Scand J Immunol, 54 (4), 428-33
DOI 10.1046/j.1365-3083.2001.00993.x, PubMed 11555411

Publications 2000

Bolstad AI, Wargelius A, Nakken B, Haga HJ, Jonsson R (2000)
Fas and Fas ligand gene polymorphisms in primary Sjögren's syndrome
J Rheumatol, 27 (10), 2397-405
PubMed 11036836

Jonsson R, Nakken B, Halse AK, Skarstein K, Brokstad K, Haga HJ (2000)
[Heredity and immunology in Sjogren's syndrome]
Tidsskr Nor Laegeforen, 120 (7), 811-4
PubMed 10806905

Page visits: 21